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Journal of Evidence-based Complementary & Alternative Medicine

Aparna Singh, Girish Singh, Kishor Patwardhan, Sangeeta Gehlot
According to Ayurveda, the traditional system of healthcare of Indian origin, Agni is the factor responsible for digestion and metabolism. Four functional states (Agnibala) of Agni have been recognized: regular, irregular, intense, and weak. The objective of the present study was to develop and validate a self-assessment tool to estimate Agnibala The developed tool was evaluated for its reliability and validity by administering it to 300 healthy volunteers of either gender belonging to 18 to 40-year age group...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Ali Fattahi, Fatemeh Niyazi, Behzad Shahbazi, Mohammad Hosein Farzaei, Gholamreza Bahrami
Rosa canina fruits have been used traditionally for the treatment of diabetes mellitus and its complications. The aim of current study was to evaluate the in vitro mechanism of action of R canina in managing diabetes mellitus. Cell proliferation and cytotoxicity assay were performed on pancreatic β-cells, βTC6. The protective activity of the extract on streptozotocin-induced death in βTC6 cells was studied. The effect of R canina on the metabolism of glucose in HepG2, a hepatocellular carcinoma cell line, was evaluated...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Mahbobeh Shirazi, Safieh Mohebitabar, Sodabeh Bioos, Mir Saeed Yekaninejad, Roja Rahimi, Zahra Shahpiri, Farhad Malekshahi, Fatemeh Nejatbakhsh
The study aimed to assess the efficacy of topical rose oil in women with pregnancy-related low back pain. A randomized controlled clinical trial was conducted on 120 women with pregnancy-related low back pain. Patients were allocated to 3 parallel groups to receive topical rose oil (in the carrier of almond oil), placebo (carrier oil), or no intervention. All groups were followed for 4 weeks. All participants were evaluated by Visual Analog Scale and the Roland-Morris Disability Questionnaires to assess the pain intensity and its impact on daily activities before and after the intervention...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Sareh Doustfatemeh, Mohammad Hadi Imanieh, Abdolali Mohagheghzade, Mohammad M Zarshenas, Zahra Torkamani, Gholamhossein Yousefi, Saman Farahangiz, Alireza Salehi
We aimed to evaluate the antidiarrheal effect of black tea in pediatric patients with acute nonbacterial diarrhea. This single-blind randomized clinical trial study was performed on 2 to 12-year-old patients, with acceptable criteria for acute nonbacterial diarrhea in Shiraz, Iran. In total, 120 patients took part in this study. Blocked randomization method was used to allocate them into 2 groups of intervention (black tea tablet + standard treatment) and control group (standard treatment; 60 patients in each)...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Dyan Wigati, Khoerul Anwar, Sudarsono, Agung Endro Nugroho
The effect of ethanolic extract of Morinda citrifolia leaves and fruit on blood pressure in dexamethasone-induced hypertension rat was evaluated. Total phenolic content of Morinda citrifolia leaves ethanolic extract (MCLEE) and Morinda citrifolia leaves ethanolic extract (MCFEE) was 1.789 ± 0.116 and 1.677 ± 0.051 mg of gallic acid equivalents per gram sample, respectively. Rutin level in MCLEE was 0.92 ± 0.19%, and scopoletin level in MCFEE was 0.46 ± 0.05%. MCLEE, MCFEE, and its extract combination significantly decreased the blood pressure of hypertensive rats...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Fatemeh Bina, Roja Rahimi
Origanum majorana L. commonly known as sweet marjoram has been used for variety of diseases in traditional and folklore medicines, including gastrointestinal, ocular, nasopharyngeal, respiratory, cardiac, rheumatologic, and neurological disorders. Essential oil containing monoterpene hydrocarbons and oxygenated monoterpenes as well as phenolic compounds are chemical constituents isolated and detected in O majorana Wide range of pharmacological activities including antioxidant, hepatoprotective, cardioprotective, anti-platelet, gastroprotective, antibacterial and antifungal, antiprotozoal, antiatherosclerosis, anti-inflammatory, antimetastatic, antitumor, antiulcer, and anticholinesterase inhibitory activities have been reported from this plant in modern medicine...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Jennifer Matthews, Jennifer L Huberty, Jenn A Leiferman, Darya McClain, Linda K Larkey
Depression affects up to 23% of pregnant women and is associated with adverse physical/mental health outcomes for both the mother and baby. Depressed pregnant women may be more likely to engage in unhealthy lifestyle behaviors that contribute to an increased risk for chronic disease. Little is known regarding depressed pregnant women's perceptions, uses of, and interests in complementary health approaches. Study participants (mean age 28.7 ± 6.8; n = 1032) included pregnant women ≥8 weeks gestation who responded to a survey assessing physical and mental health and wellness practices...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Dnyanraj Choudhary, Sauvik Bhattacharyya, Kedar Joshi
Chronic stress has been associated with a number of illnesses, including obesity. Ashwagandha is a well-known adaptogen and known for reducing stress and anxiety in humans. The objective of this study was to evaluate the safety and efficacy of a standardized root extract of Ashwagandha through a double-blind, randomized, placebo-controlled trial. A total of 52 subjects under chronic stress received either Ashwagandha (300 mg) or placebo twice daily. Primary efficacy measures were Perceived Stress Scale and Food Cravings Questionnaire...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Haider Abdul-Lateef Mousa
In recent years viral respiratory tract infections, especially influenza viruses, have had a major impact on communities worldwide as a result of unavailability of effective treatment or vaccine. The frequent alterations in the antigenic structures of respiratory viruses, particularly for RNA viruses, pose difficulties in production of effective vaccines. The unavailability of optimal medication and shortage of effective vaccines suggests the requirement for alternative natural therapies. Several herbal remedies were used for prevention and treatment viral respiratory illnesses...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Kathi J Kemper
BACKGROUND: Online training is feasible, but the impact of brief mindfulness training on health professionals needs to be better understood. METHODS: We analyzed data from health professionals and trainees who completed self-reflection exercises embedded in online mindfulness training between May 2014 and September, 2015; their changes in mindfulness were measured using standardized scales. RESULTS: Participants included nurses (34%), physicians (24%), social workers and psychologists (10%), dietitians (8%), and others (25%); 85% were women, and 20% were trainees...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Gary Null, Luanne Pennesi, Martin Feldman
This group study explored how an intervention of diet and lifestyle, including a vegan diet, fruit and vegetable juicing, nutritional supplements, regular exercise, and destressing techniques, would affect 27 subjects with anxiety, depression, poor memory, dementia, Alzheimer's disease, Parkinson's disease, history of stroke, or multiple sclerosis. Several subjects had overlapping conditions. Videotaped testimonials were obtained describing subjective results. Testimonials stated multiple benefits across all conditions addressed by the study, with subjects often reporting substantial benefits...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Kimberly Perkins, William Sahy, Robert D Beckett
The objective of this review is to identify, summarize, and evaluate clinical trials to determine the efficacy of curcuma in the treatment of osteoarthritis. A literature search for interventional studies assessing efficacy of curcuma was performed, resulting in 8 clinical trials. Studies have investigated the effect of curcuma on pain, stiffness, and functionality in patients with knee osteoarthritis. Curcuma-containing products consistently demonstrated statistically significant improvement in osteoarthritis-related endpoints compared with placebo, with one exception...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Massih Sedigh-Rahimabadi, Mohammadmehdi Fani, Mahsa Rostami-Chijan, Mohammad M Zarshenas, Mesbah Shams
This study evaluates the safety and efficacy of Punica granatum var pleniflora mouthwash in treatment of diabetic gingivitis. In a double-blind randomized clinical trial 80 patients with diabetes mellitus and gingivitis were assigned to Golnaar and chlorhexidine 0.2% groups. After using mouthwashes for 2 weeks; participants underwent tooth scaling and the last visit was 2 weeks after scaling. The primary outcome measures were plaque, modified gingival and gingival bleeding indices, and pocket depth. Both interventions had significant improvement on all of the gingival and plaque indices (P < ...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Nisha Rao, Kathi J Kemper
This study evaluated the feasibility and impact of brief online guided imagery training (up to 3 hours) for health professionals. Paired t tests were used to measure pre-to-post-training changes in stress (Perceived Stress Scale,), anxiety (Patient Reported Outcomes Measurement Information System-Anxiety Scale), empathy (Empathic Concern Scale, and Perspective-taking Scale), and self-efficacy (Self-Efficacy in providing Non-Drug Therapies Scale). Online guided imagery training attracted diverse health professionals and trainees (n = 273; 14% trainees; 34% registered nurses, 20% physicians, 14% social workers, 5% registered dititians, and 27% others)...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Maryam Mosaffa-Jahromi, Ali-Mohammad Tamaddon, Suleiman Afsharypuor, Alireza Salehi, Seyed Hassan Seradj, Mehdi Pasalar, Peyman Jafari, Kamran Bagheri Lankarani
Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. In a randomized double-blinded active and placebo controlled clinical trial, 120 participants with mild to moderate depression according to the Beck Depression Inventory-II total scores were categorized into 3 equal groups and received anise oil, Colpermin, and placebo...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Shevach Friedler, Saralee Glasser, Gila Levitan, Dana Hadar, Bat-El Sasi, Liat Lerner-Geva
This study compared responses to an in-person clown visit and a humorous film following in vitro fertilization and embryo transfer. Intervention was a 10-minute clown visit (n = 101) or 10-minute humorous video clip (n = 99). Demographic and fertility-related data and preintervention anxiety scores were collected. Participants completed an Evaluation of Intervention form postintervention. There were no group differences on demographic or fertility-related data or anxiety scores. Findings indicate while participants viewed the intervention positively, the clown visit offered a higher degree of satisfaction in more patients than did the film...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Haleh Tajadini, Nasser Zangiabadi, Kouros Divsalar, Hossein Safizadeh, Zahra Esmaili, Hossein Rafiei
BACKGROUND AND AIM: Migraine is a common form of headache that affects patients quality of life negatively. In addition to pharmacologic treatment, there are a variety of nonpharmacologic treatments for migraine headache. In present study, we examined the effect of prayer on intensity of migraine pain. METHODS: In a prospective, randomized, controlled trial from October 2013 to June 2014, this study has been conducted in Kerman, Iran. We randomly assigned 92 patients in 2 groups to receive either 40 mg of propranolol twice a day for 2 month (group "A") or 40 mg of propranolol twice a day for 2 months with prayer (group "B")...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Mahmoodreza Moein, Gholamreza Hatam, Razieh Taghavi-Moghadam, Mohammad M Zarshenas
Petroleum ether, chloroform, ethyl acetate, and n-butanol fractions of Greek juniper (Juniperus excelsa M.Bieb. from the family Cupressaceae) were evaluated for antileishmanial activities against Leishmania major promastigotes compared to meglumine antimoniate (Glucantime). In vitro toxicity assay was performed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and microplate ELISA reader. Extracts were prepared in ethanol/dimethyl sulfoxide (80/20) at 10 to 0.62 mg/mL. The standard was prepared in phosphate-buffered saline at 500 to 15...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Masoud Foroutan-Rad, Khosrow Hazrati Tappeh, Shahram Khademvatan
Leishmaniasis is caused by an obligate intracellular protozoa belonging to Leishmania genus. The current drugs for treatment of leishmaniasis possess many disadvantages; therefore, researchers are continuously looking for the more effective and safer drugs. The aim of this study is to review the effectiveness, toxicities, and possible mechanisms of pharmaceutical actions of different garlic extracts and organosulfur compounds isolated from garlic against Leishmania spp. in a variety of in vitro, in vivo and clinical trials reports...
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
Yu-Hsin Lin, Tzong-Shiun Li
Far-infrared (FIR) radiation therapy has been used for soothing effect in wound treatment. Studies have shown that FIR could enhance wound healing processes in rat models. Although these research results supported that FIR may play an important for wound healing, it had no consensus in clinical practices. It is suggested that more persuasive systemic clinical researches are needed to explore the effectiveness of FIR therapy for wound healing.
January 2017: Journal of Evidence-based Complementary & Alternative Medicine
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