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Journal of Evidence-based Complementary & Alternative Medicine

Ali Karimi, Mahmoud Rafieian-Kopaei, Mohammad-Taghi Moradi, Somayeh Alidadi
This research was aimed to evaluate anti-herpes simplex virus type-1 (anti-HSV-1) activity of crude ethanol extract and 4 corresponding fractions of Quercus brantii acorn in vitro. Crude ethanol extract was prepared and subjected to fractionation with different polarity. Anti-HSV-1 activity was evaluated on baby hamster kidney cell line using MTT assay. The inhibitory effect of the plant materials on adsorption and/or post-adsorption stages of HSV-1 replication cycle were determined. Regression analysis was used to determine 50% inhibitory concentration and 50% cytotoxicity concentration, from which selective index was calculated...
November 29, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Akbar Sheikhrabori, Mahlagha Dehghan, Fateme Ghaedi, Gholam Reza Khademi
Although modern treatments have achieved much progress in blood sugar control in recent decades, evidences indicate that complementary and alternative treatments are very common in diabetic patients. The present study aims to investigate application of complementary and traditional medicines among diabetic patients in Iran in 2016. This was a cross-sectional study done on 294 diabetic patients who were referred to the diabetes clinic and were chosen using convenient sampling. Data were gathered using a demographic characteristics form and a researcher-made questionnaire (for studying application and satisfaction of using some of the complementary and alternative medicines)...
November 6, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Romesh Kumar Bhat, Guru Deo, Ramesh Mavathur, Thaiyar Madabusi Srinivasan
INTRODUCTION: Electrophotonic imaging (EPI), also known as gas discharge visualization, is a technique of capturing images of phenomena not quantifiable by the naked eye. Different sectors at the tip of fingers represent various organs and systems as per the Chinese system of acupuncture. The images from these fingertips can be used to determine the state of health. This is done with the help of a CCD camera fitted in the EPI equipment and the specific software relevant for analysis. AIM: To observe the correlation between EPI parameters and fasting blood sugar (FBS) levels in normal, prediabetic, and diabetic study participants...
November 6, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Vita Murniati Tarawan, Kemala Isnainiasih Mantilidewi, Ika Miqra Dhini, Putri Teesa Radhiyanti, Endang Sutedja
The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound-induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups (P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups (P < ...
November 6, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Syal Kumar, Gustav J Dobos, Thomas Rampp
Traditional Indian medicine (ayurveda) is becoming increasingly popular, with many chronic conditions responding to it well. Most patients begin to take conventional medications as soon as their diagnoses are made, so ayurvedic treatments are usually undergone alongside and/or after conventional medical approaches. A detailed knowledge of the action of food, spices, and medicinal plants is needed in order to understand their potential influence fully. While societal use of ayurvedic plants and Indian spices is commonplace, without ill effect, the use of more concentrated products made from single plants, often in the form of teas or tablets, is of more concern...
October 5, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Shilpa Babbar, Karen B Williams, Dev Maulik
The use of complementary and alternative medicine during pregnancy is currently on the rise. A validated survey was conducted at the Central Association of Obstetrician and Gynecologists annual meeting to evaluate the knowledge, attitude, and practice of general obstetricians and gynecologists and maternal-fetal medicine specialists in America. We obtained 128 responses: 73 electronically (57%) and 55 via the paper survey (43%). Forty-five percent reported personally using complementary and alternative medicine and 9% of women respondents used complementary and alternative medicine during pregnancy...
October 5, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Sara Khaleghi, Mitra Bakhtiari, Atefeh Asadmobini, Farzane Esmaeili
OBJECTIVE: The object of present study was to investigate the effects of direct addition of Tribulus terrestris extract on human sperm parameters. DESIGN: Semen specimens from 40 healthy men volunteers were divided into 4 groups: one group received no treatment (control group) while the others were incubated with 20, 40, and 50 µg/mL of T terrestris extract (experimental groups). Motility, viability, and DNA fragmentation were assessed in all groups. RESULTS: The incubation of human semen with 40 and 50 μg/mL of T terrestris extract significantly enhanced total sperm motility, number of progressive motile spermatozoa, and curvilinear velocity over 60 to 120 minutes' holding time (P < ...
September 30, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Tamara L Goldsby, Michael E Goldsby, Mary McWalters, Paul J Mills
Poor mood and elevated anxiety are linked to increased incidence of disease. This study examined the effects of sound meditation, specifically Tibetan singing bowl meditation, on mood, anxiety, pain, and spiritual well-being. Sixty-two women and men (mean age 49.7 years) participated. As compared with pre-meditation, following the sound meditation participants reported significantly less tension, anger, fatigue, and depressed mood (all Ps <.001). Additionally, participants who were previously naïve to this type of meditation experienced a significantly greater reduction in tension compared with participants experienced in this meditation (P < ...
September 30, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Surasak Saokaew, Preyanate Wilairat, Paranya Raktanyakan, Piyameth Dilokthornsakul, Teerapon Dhippayom, Chuenjid Kongkaew, Rosarin Sruamsiri, Anchalee Chuthaputti, Nathorn Chaiyakunapruk
Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included...
September 30, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Sepide Miraj, Rafieian-Kopaei, Sara Kiani
Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail...
September 11, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Ishtdeep Kaur, Nancy Suthar, Jasmeen Kaur, Yogita Bansal, Gulshan Bansal
Regulatory guidelines recommend systematic stability studies on a herbal product to establish its shelf life. In the present study, commercial extracts (Types I and II) and freshly prepared extract (Type III) of Centella asiatica were subjected to accelerated stability testing for 6 months. Control and stability samples were evaluated for organoleptics, pH, moisture, total phenolic content (TPC), asiatic acid, kaempherol, and high-performance thin layer chromatography fingerprints, and for antioxidant and acetylcholinesterase inhibitory activities...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Tamara Mihic, Daniel Rainkie, Kyle John Wilby, Shane Ashley Pawluk
The clinical effectiveness and value of camel milk as a therapeutic agent is currently unclear. MEDLINE (1946 to March 2016), EMBASE (1974 to March 2016), and Google Scholar were searched using the following terms: milk, bodily secretions, camels, camelus, camelini, camelidae, dromedary, bactrian camel, body fluid, and bodily secretions. Articles identified were reviewed if the study was investigating the use of camel milk for the potential treatment of diseases affecting humans. Of 430 studies, 24 were included after assessment...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Matthew Hicks, Douglas Hanes, Helané Wahbeh
Expectancy, arguably the prime component of the placebo effect, has been shown to significantly modify the effects of many treatments. Furthermore, various forms of mind-body interventions have demonstrated effective improvements in outcomes. The aim of this study was to examine the relationship between pretreatment expectations and symptom reduction in a secondary analysis of 3 mind-body intervention programs. An adjusted correlation and regression analysis compared data from a 6-question expectancy questionnaire to a self-reported clinical impression of change score...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Nasrin Babadaei Samani, Azam Jokar, Mahmood Soveid, Mojtaba Heydari, Seyed Hamdollah Mosavat
AIM: Considering traditional use of Tribulus terrestris in diabetes and proven antihyperglycemic and antihyperlipidemic effects of T terrestris in animal studies, we aimed to evaluate the efficacy of the hydroalcoholic extract of T terrestris on the serum glucose and lipid profile of women with non-insulin-dependent diabetes mellitus. METHODS: Ninety-eight women with diabetes mellitus type 2 were randomly allocated to receive the T terrestris (1000 mg/d) or placebo for 3 months...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Sedighe Albakhit, Shahram Khademvatan, Monir Doudi, Masoud Foroutan-Rad
Leishmaniasis is considered as a major public health problem worldwide. Current drugs in treatment of leishmaniasis have some limitations; thus, the current study was aimed to assess the methanolic extracts of pit and fruit of Phoenix dactylifera against Leishmania major promastigotes. L major promastigotes were cultured in RPMI 1640 and incubated at 25°C ± 1°C for 24, 48, and 72 hours. For obtaining the IC50 (half maximal inhibitory concentration) value, MTT assay was employed. Furthermore, promastigotes were examined in terms of morphology under light microscope...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Mosayeb Noori Ahmad Abadi, Mohsen Mortazavi, Navid Kalani, Hadi Zare Marzouni, Wesam Kooti, Sara Ali-Akbari
In today's stressful world, psychopathy (especially anxiety) is receiving increased importance. Most of the drugs used to treat this disease have several side effects. Medicinal plants derived from natural products have fewer side effects and can be used in the treatment of this disease. The aim of this study was to evaluate the effect of the hydroalcoholic extract of Rosmarinus officinalis L. on anxiety in mice. In this experimental study, 50 male mice were randomly divided into 5 groups. To evaluate anxiety, the Elevated Plus Maze test was performed...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Agung Endro Nugroho, Agustin Wijayanti, Mutmainah Mutmainah, Rina Susilowati, Nuning Rahmawati
Licorice (Glycyrrhiza glabra), Pulasari stem bark (Alyxia reinwardtii) and Sembung leaf (Blumea balsamifera) are traditionally used to treat gastrointestinal disorders. The aim of the study was to investigate gastroprotective effect of hot water extracts combination of those herbal against aspirin-induced gastric ulcer model in rats. The combination consisted of fixed doses of Licorice 273 mg/kg BW and Sembung leaf 457.5 mg/kg BW, and also consisted of Pulasari stem in various doses i.e. 100 mg/kg BW (first group), 200 mg/kg BW (second and sixth group) and 300 mg/kg BW (third group)...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Mohammad Reza Saidi, Mohammad Hosein Farzaei, Shahram Miraghaee, Atefeh Babaei, Bahareh Mohammadi, Mohammad Taher Bahrami, Gholamreza Bahrami
Prosopis farcta root has been proposed as an efficacious natural drug for cardiovascular disorders in traditional medicine. The present study evaluates the efficacy of aqueous extract of Prosopis farcta root on experimental atherosclerosis development in rabbits with high cholesterol diet-induced hypercholesterolemia. Serum lipid parameters were significantly increased in the high cholesterol diet groups in comparison with the normal control group (P < .050). Histopathological findings revealed that atheromatous plaques were formed in both thoracic and abdominal aorta of hypercholestrolemic rabbits...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Habib Ghaznavi, Saeed Mehrzadi, Banafshe Dormanesh, Seyyed Mohammad Taghi Hosseini Tabatabaei, Habib Vahedi, Azam Hosseinzadeh, HamidReza Pazoki-Toroudi, Amir Rashidian
This study compared the possible protective effects of silymarin and melatonin against gentamicin (GEN)-induced nephrotoxicity in rats. Rats were allocated to 6 groups: Group I, control group; Groups II and III, administered with silymarin or melatonin; Group IV, injected with GEN; and Groups V and VI, administered with silymarin or melatonin, and then injected with GEN. Compared with the rats in the control group, all rats injected with GEN significantly presented elevated levels of serum creatinine and urea that was accompanied by an increase in relative kidney weight, increase in renal reactive oxygen species (ROS) and malondialdehyde (MDA) levels, and reduction in renal glutathione (GSH) level and superoxide dismutase (SOD) activity...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
Stephen A Adefegha, Olasunkanmi S Omojokun, Ganiyu Oboh, Olasunkanmi Fasakin, Opeyemi Ogunsuyi
Studies have shown the pharmacological relevance of phenolics like ferulic acid (FA) in promoting health. This study sought to investigate the modulatory effects of FA on cadmium-induced brain damage in rats. Brain damage was induced in Wistar strain rats by oral administration of cadmium (5 mg/kg body weight) for 21 days. Assays for malondialdehyde (MDA) content, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), monoamine oxidase (MAO), and Na(+)/K(+)-ATPase activities were carried out. The study revealed significant (P < ...
October 2016: Journal of Evidence-based Complementary & Alternative Medicine
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