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Diabetes & Metabolism Journal

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https://www.readbyqxmd.com/read/29199410/non-alcoholic-fatty-liver-disease-the-emerging-burden-in-cardiometabolic-and-renal-diseases
#1
REVIEW
Eugene Han, Yong Ho Lee
As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 diabetes mellitus, metabolic syndrome, dyslipidemia, hypertension, cardiovascular or cerebrovascular diseases, and chronic kidney disease. Non-alcoholic steatohepatitis, an advanced type of NAFLD, can aggravate these inter-organ relationships and lead to poorer outcomes...
November 17, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199409/depressive-symptoms-are-negatively-associated-with-glucose-testing-and-eating-meals-on-time-among-individuals-with-diabetes-in-zambia
#2
Given Hapunda, Amina Abubakar, Frans Pouwer, Fons van de Vijver
BACKGROUND: Depression is an established risk factor for cardiovascular diseases and mortality among individuals living with diabetes, and impaired self-care behaviors may play a mediating role. In Africa, this association is not very well known. In this study, we examined the associations between depressive symptoms and different aspects of diabetes self-care in Zambian individuals with diabetes mellitus. METHODS: A total of 157 individuals with diabetes mellitus participated...
November 17, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199408/beneficial-effects-of-aerobic-exercise-training-combined-with-rosiglitazone-on-glucose-metabolism-in-otsuka-long-evans-tokushima-fatty-rats
#3
Shan Ji Piao, So Hun Kim, Young Ju Suh, Seong Bin Hong, Seong Hee Ahn, Da Hae Seo, In Sun Park, Moonsuk Nam
BACKGROUND: Regular aerobic exercise is essential for the prevention and management of type 2 diabetes mellitus and may be particularly beneficial for those treated with thiazolidinediones, since it may prevent associated weight gain. This study aimed to evaluate the effect of combined exercise and rosiglitazone treatment on body composition and glucose metabolism in obese diabetes-prone animals. METHODS: We analyzed metabolic parameters, body composition, and islet profiles in Otsuka Long Evans Tokushima Fatty rats after 28 weeks of aerobic exercise, rosiglitazone treatment, and combined exercise and rosiglitazone treatment...
November 15, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199407/adipokines-and-insulin-resistance-according-to-characteristics-of-pregnant-women-with-gestational-diabetes-mellitus
#4
Eon Ju Jeon, Seong Yeon Hong, Ji Hyun Lee
BACKGROUND: The aim of this study was to evaluate adipokines concentration and insulin resistance according to maternal age or obesity at pregnancy and weight change at diagnosed gestational diabetes mellitus (GDM) in pregnant women with GDM. METHODS: This study included 57 pregnant women who were diagnosed with GDM at 24 to 28 weeks of gestation. The subjects were classified into two or three groups according to pre-pregnancy body mass index (BMI, <25 kg/m² vs...
November 15, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199406/the-role-of-negative-affect-in-the-assessment-of-quality-of-life-among-women-with-type-1-diabetes-mellitus
#5
Nicola R Gawlik, Malcolm J Bond
BACKGROUND: The purpose of this study is to determine the impact of negative affect (defined in terms of lack of optimism, depressogenic attributional style, and hopelessness depression) on the quality of life of women with type 1 diabetes mellitus. METHODS: Participants (n=177) completed either an online or paper questionnaire made available to members of Australian diabetes support groups. Measures of optimism, attributional style, hopelessness depression, disease-specific data, and diabetes-related quality of life were sought...
November 7, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199405/serum-betatrophin-concentrations-and-the-risk-of-incident-diabetes-a-nested-case-control-study-from-chungju-metabolic-disease-cohort
#6
Seung Hwan Lee, Marie Rhee, Hyuk Sang Kwon, Yong Moon Park, Kun Ho Yoon
BACKGROUND: Betatrophin is a newly identified hormone derived from the liver and adipose tissue, which has been suggested to regulate glucose and lipid metabolism. Circulating levels of betatrophin are altered in various metabolic diseases, although the results are inconsistent. We aimed to examine whether betatrophin is a useful biomarker in predicting the development of diabetes. METHODS: A nested case-control study was performed using a prospective Chungju Metabolic disease Cohort Study...
November 3, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29272085/response-features-of-long-standing-korean-type-2-diabetes-mellitus-patients-with-diabetic-retinopathy-a-study-based-on-standardized-clinical-data-diabetes-metab-j-2017-41-393-404
#7
LETTER
Sang Youl Rhee, Jeong Taek Woo
No abstract text is available yet for this article.
December 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29272084/letter-features-of-long-standing-korean-type-2-diabetes-mellitus-patients-with-diabetic-retinopathy-a-study-based-on-standardized-clinical-data-diabetes-metab-j-2017-41-393-404
#8
LETTER
https://www.readbyqxmd.com/read/29272083/association-of-self-care-behaviors-and-quality-of-life-among-patients-with-type-2-diabetes-mellitus-chaldoran-county-iran
#9
Towhid Babazadeh, Mostafa Dianatinasab, Amin Daemi, Hossein Ali Nikbakht, Fatemeh Moradi, Saber Ghaffari-Fam
BACKGROUND: Self-care of diabetes is an essential part for controlling the disease and improvement of quality of life in type 2 diabetes mellitus (T2DM) patients. This study aimed to analyze the associated factors of quality of life in patients with T2DM in order to design effective interventions. METHODS: This cross-sectional study was conducted on 120 T2DM patients referred to health centers of Chaldoran, West Azerbaijan Province, Iran. The quality of life's questionnaires from World Health Organization and the self-care behaviors' questionnaires were used for data collection...
December 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29272082/simple-screening-using-ultrasonography-for-prediction-of-gestational-diabetes-mellitus
#10
EDITORIAL
Seung Min Chung, Jun Sung Moon
No abstract text is available yet for this article.
December 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29272081/glucagon-like-peptide-1-receptor-agonists-for-the-treatment-of-type-2-diabetes-mellitus-a-position-statement-of-the-korean-diabetes-association
#11
REVIEW
Hyun Jin Kim, Seok O Park, Seung Hyun Ko, Sang Youl Rhee, Kyu Yeon Hur, Nan Hee Kim, Min Kyong Moon, Byung Wan Lee, Jin Hwa Kim, Kyung Mook Choi
The glucagon-like peptide-1 receptor agonists (GLP-1RAs) were recommended as a monotherapy or combination therapy with oral hypoglycemic agents or basal insulin in the position statement of the Korean Diabetes Association 2017 for pharmacological therapy. Many randomized clinical trials and systematic reviews report that GLP-1RAs have considerable glucose-lowering effect and lead to weight reduction and low risk of hypoglycemia when used as a monotherapy or combination therapy. The cardiovascular safety of GLP-1RAs has been assessed in several randomized clinical trials and systematic reviews...
December 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29199411/the-phospholipid-linoleoylglycerophosphocholine-as-a-biomarker-of-directly-measured-insulin-resistance
#12
Maria Camila Pérez-Matos, Martha Catalina Morales-Álvarez, Freddy Jean Karlo Toloza, Maria Laura Ricardo-Silgado, Jose Oscar Mantilla-Rivas, Jairo Arturo Pinzón-Cortes, Maritza Perez-Mayorga, Elizabeth Jiménez, Edwin Guevara, Carlos O Mendivil
BACKGROUND: Plasma concentrations of some lysophospholipids correlate with metabolic alterations in humans, but their potential as biomarkers of insulin resistance (IR) is insufficiently known. We aimed to explore the association between plasma linoleoylglycerophosphocholine (LGPC) and objective measures of IR in adults with different metabolic profiles. METHODS: We studied 62 men and women, ages 30 to 69 years, (29% normal weight, 59% overweight, 12% obese). Participants underwent a 5-point oral glucose tolerance test (5p-OGTT) from which we calculated multiple indices of IR and insulin secretion...
December 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086542/corrigendum-author-s-name-and-affiliation-correction-the-effect-of-12-weeks-aerobic-resistance-and-combined-exercises-on-omentin-1-levels-and-insulin-resistance-among-type-2-diabetic-middle-aged-women
#13
Zeinab AminiLari, Mohammad Fararouei, Sasan Amanat, Ehsan Sinaei, Aria Dianatinasab, Mahmood AminiLari, Nima Daneshi, Mostafa Dianatinasab
This corrects the article on p. 205 in vol. 41, PMID: 28537059.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086541/response-effects-of-high-dose-%C3%AE-lipoic-acid-on-heart-rate-variability-of-type-2-diabetes-mellitus-patients-with-cardiac-autonomic-neuropathy-in-korea-diabetes-metab-j-2017-41-275-83
#14
LETTER
Chong Hwa Kim, Sol Jae Lee, Bong Yun Cha
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086540/letter-effects-of-high-dose-%C3%AE-lipoic-acid-on-heart-rate-variability-of-type-2-diabetes-mellitus-patients-with-cardiac-autonomic-neuropathy-in-korea-diabetes-metab-j-2017-41-275-83
#15
LETTER
Jeongmin Lee, Jae Hyoung Cho
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086539/generation-of-insulin-expressing-cells-in-mouse-small-intestine-by-pdx1-mafa-and-beta2-neurod
#16
So Hyun Lee, Marie Rhee, Ji Won Kim, Kun Ho Yoon
BACKGROUND: To develop surrogate insulin-producing cells for diabetes therapy, adult stem cells have been identified in various tissues and studied for their conversion into β-cells. Pancreatic progenitor cells are derived from the endodermal epithelium and formed in a manner similar to gut progenitor cells. Here, we generated insulin-producing cells from the intestinal epithelial cells that induced many of the specific pancreatic transcription factors using adenoviral vectors carrying three genes: PMB (pancreatic and duodenal homeobox 1 [Pdx1], V-maf musculoaponeurotic fibrosarcoma oncogene homolog A [MafA], and BETA2/NeuroD)...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086538/features-of-long-standing-korean-type-2-diabetes-mellitus-patients-with-diabetic-retinopathy-a-study-based-on-standardized-clinical-data
#17
Sejeong Park, Sang Youl Rhee, Su Jin Jeong, Kiyoung Kim, Suk Chon, Seung Young Yu, Jeong Taek Woo
BACKGROUND: This is part of a prospective study carried out as a national project to secure standardized public resources for type 2 diabetes mellitus (T2DM) patients in Korea. We compared various characteristics of long-standing T2DM patients with diabetic retinopathy (DR) and macular edema (ME). METHODS: From September 2014 to July 2015, T2DM patients with disease duration of at least 15 years were recruited at a single university hospital. Clinical data and samples were collected according to the common data elements and standards of procedure developed by the Korean Diabetes Association Research Council...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086537/performance-of-the-achutha-menon-centre-diabetes-risk-score-in-identifying-prevalent-diabetes-in-tamil-nadu-india
#18
Anu Mary Oommen, Vinod Joseph Abraham, Thirunavukkarasu Sathish, V Jacob Jose, Kuryan George
BACKGROUND: The Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu, and compared it with other diabetes risk scores developed from India. METHODS: We used the data from 4,896 participants (30 to 64 years) of a cross-sectional study conducted in Vellore (2010 to 2012), to calculate the AMCDRS scores using age, family history, and waist circumference...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086536/effects-of-lobeglitazone-a-novel-thiazolidinedione-on-bone-mineral-density-in-patients-with-type-2-diabetes-mellitus-over-52-weeks
#19
Soo Lim, Kyoung Min Kim, Sin Gon Kim, Doo Man Kim, Jeong Taek Woo, Choon Hee Chung, Kyung Soo Ko, Jeong Hyun Park, Yongsoo Park, Sang Jin Kim, Hak Chul Jang, Dong Seop Choi
BACKGROUND: The aim of this multicenter, randomized, double-blind study was to examine the effect of lobeglitazone, a novel thiazolidinedione, on the changes in bone mineral density (BMD) in patients with type 2 diabetes mellitus. METHODS: A 24-week, double-blinded phase was followed by a 28-week, open-label phase, in which the placebo group also started to receive lobeglitazone. A total of 170 patients aged 34 to 76 years were randomly assigned in a 2:1 ratio to receive lobeglitazone 0...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086535/changes-in-the-bone-mineral-density-of-femur-neck-and-total-hip-over-a-52-week-treatment-with-lobeglitazone
#20
EDITORIAL
Da Young Lee, Ji A Seo
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
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