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Diabetes & Metabolism Journal

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https://www.readbyqxmd.com/read/28447443/response-efficacy-of-moderate-intensity-statins-in-the-treatment-of-dyslipidemia-in-korean-patients-with-type-2-diabetes-mellitus-diabetes-metab-j-2017-41-23-30
#1
LETTER
Sung Hye Kong, Bo Kyung Koo, Min Kyong Moon
No abstract text is available yet for this article.
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447442/letter-efficacy-of-moderate-intensity-statins-in-the-treatment-of-dyslipidemia-in-korean-patients-with-type-2-diabetes-mellitus-diabetes-metab-j-2017-41-23-30
#2
LETTER
https://www.readbyqxmd.com/read/28447441/a-cutoff-for-age-at-menarche-predicting-metabolic-syndrome-in-egyptian-overweight-obese-premenopausal-women
#3
Ibrahim Elsehely, Hala Abdel Hafez, Mohammed Ghonem, Ali Fathi, Rasha Elzehery
Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff for age at menarche discriminating presence or absence of metabolic syndrome in overweight/obese premenopausal women. This study included 204 overweight/obese women. Metabolic syndrome was defined according to NCEP-ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447440/addition-of-ipragliflozin-to-metformin-treatment-in-korean-patients-with-type-2-diabetes-mellitus-subgroup-analysis-of-a-phase-3-trial
#4
Kyung Wan Min, Bon Jeong Ku, Ji Hyun Lee, Min Seon Kim, Kyu Jeung Ahn, Moon Kyu Lee, Satoshi Kokubo, Satoshi Yoshida, Hyun Ji Cho, Bong Soo Cha
BACKGROUND: This is a subgroup analysis of Korean patients from a phase 3 clinical trial investigating the efficacy and safety of ipragliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin. METHODS: This multicenter, placebo-controlled, double-blind, parallel-group study was carried out between November 2011 and January 2013. Patients entered a 2-week placebo pretreatment period, followed by a 24-week treatment period with either ipragliflozin (50 mg/day) or placebo, while continuing metformin...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447439/lipid-abnormalities-in-type-2-diabetes-mellitus-patients-with-overt-nephropathy
#5
Sabitha Palazhy, Vijay Viswanathan
BACKGROUND: Diabetic nephropathy is a major complication of diabetes and an established risk factor for cardiovascular events. Lipid abnormalities occur in patients with diabetic nephropathy, which further increase their risk for cardiovascular events. We compared the degree of dyslipidemia among type 2 diabetes mellitus (T2DM) subjects with and without nephropathy and analyzed the factors associated with nephropathy among them. METHODS: In this retrospective study, T2DM patients with overt nephropathy were enrolled in the study group (n=89) and without nephropathy were enrolled in the control group (n=92)...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447438/diabetes-camp-as-continuing-education-for-diabetes-self-management-in-middle-aged-and-elderly-people-with-type-2-diabetes-mellitus
#6
So Young Park, Sun Young Kim, Hye Mi Lee, Kyu Yeon Hur, Jae Hyeon Kim, Moon Kyu Lee, Kang Hee Sim, Sang Man Jin
BACKGROUND: Despite the established benefits of diabetes camps for the continuing education of children with type 1 diabetes mellitus, little is known about the long-term metabolic benefits of diabetes camps for middle-aged and elderly people with type 2 diabetes mellitus (T2DM), especially in terms of glycosylated hemoglobin (HbA1c) variability. METHODS: The 1-year mean and variability of HbA1c before and after the diabetes camp was compared between the participants of the diabetes camp (n=57; median age 65 years [range, 50 to 86 years]; median diabetes duration 14 years [range, 1 to 48 years])...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447437/association-between-blood-mercury-level-and-visceral-adiposity-in-adults
#7
EDITORIAL
Seong Su Moon
No abstract text is available yet for this article.
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447436/role-of-no-vasp-signaling-pathway-against-obesity-related-inflammation-and-insulin-resistance
#8
REVIEW
Yu Mi Kang, Francis Kim, Woo Je Lee
Obesity has quickly become a worldwide pandemic, causing major adverse health outcomes such as dyslipidemia, type 2 diabetes mellitus, cardiovascular disease and cancers. Obesity-induced insulin resistance is the key for developing these metabolic disorders, and investigation to understand the molecular mechanisms involved has been vibrant for the past few decades. Of these, low-grade chronic inflammation is suggested as a critical concept in the development of obesity-induced insulin resistance, and the anti-inflammatory effect of nitric oxide (NO) signaling has been reported to be linked to improvement of insulin resistance in multiple organs involved in glucose metabolism...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28447435/a-clinical-practice-guideline-to-guide-a-system-approach-to-diabetes-care-in-hong-kong
#9
REVIEW
Ip Tim Lau
The Hospital Authority of Hong Kong is a statutory body that manages all the public medical care institutions in Hong Kong. There are currently around 400,000 diabetic patients under its care at 17 hospitals (providing secondary care for 40%) and 73 General Outpatient Clinics (providing primary care for 60%). The patient population has been growing at 6% to 8% per year over the past 5 years, estimated to include over 95% of all diagnosed patients in Hong Kong. In order to provide equitable and a minimal level of care within resources and local system factors constraints, a Clinical Practice Guideline on the management of type 2 diabetes mellitus was drawn in 2013 to guide a system approach to providing diabetes care...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28029015/association-between-blood-mercury-level-and-visceral-adiposity-in-adults
#10
Jong Suk Park, Kyoung Hwa Ha, Ka He, Dae Jung Kim
BACKGROUND: Few studies have examined the association between mercury exposure and obesity. The aim of this study is to investigate the association between blood mercury concentrations and indices of obesity in adults. METHODS: A total of 200 healthy subjects, aged 30 to 64 years, who had no history of cardiovascular or malignant disease, were examined. Anthropometric and various biochemical profiles were measured. Visceral adipose tissue (VAT) was measured using dual-energy X-ray absorptiometry (DXA)...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28029014/regulating-hypothalamus-gene-expression-in-food-intake-dietary-composition-or-calorie-density
#11
Mi Jang, So Young Park, Yong Woon Kim, Seung Pil Jung, Jong Yeon Kim
BACKGROUND: The proportion of saturated fatty acids/unsaturated fatty acids in the diet seems to act as a physiological regulation on obesity, cardiovascular diseases, and diabetes. Differently composed fatty acid diets may induce satiety of the hypothalamus in different ways. However, the direct effect of the different fatty acid diets on satiety in the hypothalamus is not clear. METHODS: Three experiments in mice were conducted to determine whether: different compositions of fatty acids affects gene mRNA expression of the hypothalamus over time; different types of fatty acids administered into the stomach directly affect gene mRNA expression of the hypothalamus; and fat composition changes in the diet affects gene mRNA expression of the hypothalamus...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236386/corrigendum-author-orcid-number-correction-dietary-sodium-intake-in-patients-with-type-2-diabetes-mellitus
#12
Mi Kyung Kim
This corrects the article on p. 280 in vol. 40, PMID: 27550209.
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236385/response-clinical-course-and-risk-factors-of-diabetic-retinopathy-in-patients-with-type-2-diabetes-mellitus-in-korea-diabetes-metab-j-2016-40-482-93
#13
LETTER
Jae Seung Yun, Seung Hyun Ko
No abstract text is available yet for this article.
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236384/letter-clinical-course-and-risk-factors-of-diabetic-retinopathy-in-patients-with-type-2-diabetes-mellitus-in-korea-diabetes-metab-j-2016-40-482-93
#14
LETTER
Nam Hoon Kim
No abstract text is available yet for this article.
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236383/practical-focus-on-american-diabetes-association-european-association-for-the-study-of-diabetes-consensus-algorithm-in-patients-with-type-2-diabetes-mellitus-timely-insulin-initiation-and-titration-iran-afect
#15
Mohammad Ebrahim Khamseh, Gholamreza Yousefzadeh, Zahra Banazadeh, Sahar Ghareh
BACKGROUND: The aim of this study was to evaluate the safety and effectiveness of insulin glargine in a large population from a variety of clinical care in Iranian people with type 2 diabetes mellitus (T2DM) and to measure the percentage of patients achieving glycosylated hemoglobin (HbA1c) <7% by the end of 24 weeks of treatment in routine clinical practice. METHODS: This study was a 24 week, observational study of patients with T2DM, for whom the physician had decided to initiate or to switch to insulin glargine...
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236382/re-evaluation-of-efficacy-of-moderate-intensity-statins-in-korean-patients-with-type-2-diabetes-mellitus
#16
EDITORIAL
Soo Kyoung Kim
No abstract text is available yet for this article.
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236381/nuclear-receptors-resolve-endoplasmic-reticulum-stress-to-improve-hepatic-insulin-resistance
#17
REVIEW
Jae Man Lee
Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resistance. The mechanistic basis for these antidiabetic effects has primarily been attributed to multiple metabolic and inflammatory functions. Here we review recent advances in our understanding of the association of ER stress with insulin resistance and the role of nuclear receptors in promoting ER stress resolution and improving insulin resistance in the liver...
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28236380/my-sweetheart-is-broken-role-of-glucose-in-diabetic-cardiomyopathy
#18
REVIEW
Manoja K Brahma, Mark E Pepin, Adam R Wende
Despite overall reductions in heart disease prevalence, the risk of developing heart failure has remained 2-fold greater among people with diabetes. Growing evidence has supported that fluctuations in glucose level and uptake contribute to cardiovascular disease (CVD) by modifying proteins, DNA, and gene expression. In the case of glucose, clinical studies have shown that increased dietary sugars for healthy individuals or poor glycemic control in diabetic patients further increased CVD risk. Furthermore, even after decades of maintaining tight glycemic control, susceptibility to disease progression can persist following a period of poor glycemic control through a process termed "glycemic memory...
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28029018/exenatide-versus-insulin-lispro-added-to-basal-insulin-in-a-subgroup-of-korean-patients-with-type-2-diabetes-mellitus
#19
Kun Ho Yoon, Elise Hardy, Jenny Han
BACKGROUND: The prevalence of type 2 diabetes mellitus (T2DM) and obesity is increasing in Korea. Clinical studies in patients with T2DM have shown that combining the glucagon-like peptide-1 receptor agonist exenatide twice daily with basal insulin is an effective glucose-lowering strategy. However, these studies were predominantly conducted in non-Asian populations. METHODS: We conducted a subgroup analysis of data from a multinational, 30-week, randomized, open-label trial to compare the effects of exenatide twice daily (n=10) or three times daily mealtime insulin lispro (n=13) among Korean patients with T2DM inadequately controlled (glycosylated hemoglobin [HbA1c] >7...
February 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28029017/serum-calcium-and-the-risk-of-incident-metabolic-syndrome-a-4-3-year-retrospective-longitudinal-study
#20
Jong Ha Baek, Sang Man Jin, Ji Cheol Bae, Jae Hwan Jee, Tae Yang Yu, Soo Kyoung Kim, Kyu Yeon Hur, Moon Kyu Lee, Jae Hyeon Kim
BACKGROUND: An association between serum calcium level and risk of metabolic syndrome (MetS) has been suggested in cross-sectional studies. This study aimed to evaluate the association between baseline serum calcium level and risk of incident MetS in a longitudinal study. METHODS: We conducted a retrospective longitudinal study of 12,706 participants without MetS who participated in a health screening program, had normal range serum calcium level at baseline (mean age, 51 years), and were followed up for 4...
February 2017: Diabetes & Metabolism Journal
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