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Diabetes & Metabolism Journal

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https://www.readbyqxmd.com/read/29086542/corrigendum-author-s-name-and-affiliation-correction-the-effect-of-12-weeks-aerobic-resistance-and-combined-exercises-on-omentin-1-levels-and-insulin-resistance-among-type-2-diabetic-middle-aged-women
#1
Zeinab AminiLari, Mohammad Fararouei, Sasan Amanat, Ehsan Sinaei, Aria Dianatinasab, Mahmood AminiLari, Nima Daneshi, Mostafa Dianatinasab
This corrects the article on p. 205 in vol. 41, PMID: 28537059.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086541/response-effects-of-high-dose-%C3%AE-lipoic-acid-on-heart-rate-variability-of-type-2-diabetes-mellitus-patients-with-cardiac-autonomic-neuropathy-in-korea-diabetes-metab-j-2017-41-275-83
#2
LETTER
Chong Hwa Kim, Sol Jae Lee, Bong Yun Cha
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086540/letter-effects-of-high-dose-%C3%AE-lipoic-acid-on-heart-rate-variability-of-type-2-diabetes-mellitus-patients-with-cardiac-autonomic-neuropathy-in-korea-diabetes-metab-j-2017-41-275-83
#3
LETTER
Jeongmin Lee, Jae Hyoung Cho
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086539/generation-of-insulin-expressing-cells-in-mouse-small-intestine-by-pdx1-mafa-and-beta2-neurod
#4
So Hyun Lee, Marie Rhee, Ji Won Kim, Kun Ho Yoon
BACKGROUND: To develop surrogate insulin-producing cells for diabetes therapy, adult stem cells have been identified in various tissues and studied for their conversion into β-cells. Pancreatic progenitor cells are derived from the endodermal epithelium and formed in a manner similar to gut progenitor cells. Here, we generated insulin-producing cells from the intestinal epithelial cells that induced many of the specific pancreatic transcription factors using adenoviral vectors carrying three genes: PMB (pancreatic and duodenal homeobox 1 [Pdx1], V-maf musculoaponeurotic fibrosarcoma oncogene homolog A [MafA], and BETA2/NeuroD)...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086538/features-of-long-standing-korean-type-2-diabetes-mellitus-patients-with-diabetic-retinopathy-a-study-based-on-standardized-clinical-data
#5
Sejeong Park, Sang Youl Rhee, Su Jin Jeong, Kiyoung Kim, Suk Chon, Seung Young Yu, Jeong Taek Woo
BACKGROUND: This is part of a prospective study carried out as a national project to secure standardized public resources for type 2 diabetes mellitus (T2DM) patients in Korea. We compared various characteristics of long-standing T2DM patients with diabetic retinopathy (DR) and macular edema (ME). METHODS: From September 2014 to July 2015, T2DM patients with disease duration of at least 15 years were recruited at a single university hospital. Clinical data and samples were collected according to the common data elements and standards of procedure developed by the Korean Diabetes Association Research Council...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086537/performance-of-the-achutha-menon-centre-diabetes-risk-score-in-identifying-prevalent-diabetes-in-tamil-nadu-india
#6
Anu Mary Oommen, Vinod Joseph Abraham, Thirunavukkarasu Sathish, V Jacob Jose, Kuryan George
BACKGROUND: The Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu, and compared it with other diabetes risk scores developed from India. METHODS: We used the data from 4,896 participants (30 to 64 years) of a cross-sectional study conducted in Vellore (2010 to 2012), to calculate the AMCDRS scores using age, family history, and waist circumference...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086536/effects-of-lobeglitazone-a-novel-thiazolidinedione-on-bone-mineral-density-in-patients-with-type-2-diabetes-mellitus-over-52-weeks
#7
Soo Lim, Kyoung Min Kim, Sin Gon Kim, Doo Man Kim, Jeong Taek Woo, Choon Hee Chung, Kyung Soo Ko, Jeong Hyun Park, Yongsoo Park, Sang Jin Kim, Hak Chul Jang, Dong Seop Choi
BACKGROUND: The aim of this multicenter, randomized, double-blind study was to examine the effect of lobeglitazone, a novel thiazolidinedione, on the changes in bone mineral density (BMD) in patients with type 2 diabetes mellitus. METHODS: A 24-week, double-blinded phase was followed by a 28-week, open-label phase, in which the placebo group also started to receive lobeglitazone. A total of 170 patients aged 34 to 76 years were randomly assigned in a 2:1 ratio to receive lobeglitazone 0...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086535/changes-in-the-bone-mineral-density-of-femur-neck-and-total-hip-over-a-52-week-treatment-with-lobeglitazone
#8
EDITORIAL
Da Young Lee, Ji A Seo
No abstract text is available yet for this article.
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086534/insulin-therapy-for-adult-patients-with-type-2-diabetes-mellitus-a-position-statement-of-the-korean-diabetes-association-2017
#9
REVIEW
Byung Wan Lee, Jin Hwa Kim, Seung Hyun Ko, Kyu Yeon Hur, Nan Hee Kim, Sang Youl Rhee, Hyun Jin Kim, Min Kyong Moon, Seok O Park, Kyung Mook Choi
The Korean Diabetes Association (KDA) has regularly updated its Clinical Practice Guidelines. In 2017, the KDA published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). Growing evidence from new multinational clinical trials using novel and traditional insulin analogues has also been accumulated. Following global trends, many results of clinical trials, especially concerning the clinical efficacy and safety of insulin therapy, have been published about Korean patients with T2DM...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086533/combination-therapy-of-oral-hypoglycemic-agents-in-patients-with-type-2-diabetes-mellitus
#10
REVIEW
Min Kyong Moon, Kyu Yeon Hur, Seung Hyun Ko, Seok O Park, Byung Wan Lee, Jin Hwa Kim, Sang Youl Rhee, Hyun Jin Kim, Kyung Mook Choi, Nan Hee Kim
The Korean Diabetes Association (KDA) recently updated the Clinical Practice Guidelines on antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus (T2DM). In combination therapy of oral hypoglycemic agents (OHAs), general recommendations were not changed from those of the 2015 KDA guidelines. The Committee on Clinical Practice Guidelines of the KDA has extensively reviewed and discussed the results of meta-analyses and systematic reviews of effectiveness and safety of OHAs and many clinical trials on Korean patients with T2DM for the update of guidelines...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086532/monotherapy-in-patients-with-type-2-diabetes-mellitus
#11
REVIEW
Sang Youl Rhee, Hyun Jin Kim, Seung Hyun Ko, Kyu Yeon Hur, Nan Hee Kim, Min Kyong Moon, Seok O Park, Byung Wan Lee, Kyung Mook Choi, Jin Hwa Kim
In order to improve the quality of life and to prevent chronic complications related to diabetes mellitus, intensive lifestyle modification and proper medication are needed from the early stage of diagnosis of type 2 diabetes mellitus (T2DM). When using the first medication for diabetic patients, the appropriate treatment should be selected considering the clinical characteristics of the patient, efficacy of the drug, side effects, and cost. In general, the use of metformin as the first treatment for oral hypoglycemic monotherapy is recommended because of its excellent blood glucose-lowering effect, relatively low side effects, long-term proven safety, low risk of hypoglycemia, and low weight gain...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086531/antihyperglycemic-agent-therapy-for-adult-patients-with-type-2-diabetes-mellitus-2017-a-position-statement-of-the-korean-diabetes-association
#12
REVIEW
Seung Hyun Ko, Kyu Yeon Hur, Sang Youl Rhee, Nan Hee Kim, Min Kyong Moon, Seok O Park, Byung Wan Lee, Hyun Jin Kim, Kyung Mook Choi, Jin Hwa Kim
In 2017, the Korean Diabetes Association (KDA) published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). The KDA regularly updates its Clinical Practice Guidelines, but since the last update in 2015, many results from clinical trials have been introduced, and domestic data from studies performed in Korean patients with T2DM have been published. Recently, evidence from large clinical studies assessing cardiovascular outcomes following the use of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in patients with T2DM were incorporated into the recommendations...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29086530/skeletal-muscle-thermogenesis-and-its-role-in-whole-body-energy-metabolism
#13
REVIEW
Muthu Periasamy, Jose Luis Herrera, Felipe C G Reis
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both are difficult to enforce. There has been renewed interest in exploiting pathways such as uncoupling protein 1 (UCP1)-mediated uncoupling in brown adipose tissue (BAT) and white adipose tissue to increase energy expenditure to control weight gain. However, relying on UCP1-based thermogenesis alone may not be sufficient to control obesity in humans...
October 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868831/response-the-effect-of-12-weeks-aerobic-resistance-and-combined-exercises-on-omentin-1-levels-and-insulin-resistance-among-type-2-diabetic-middle-aged-women-diabetes-metab-j-2017-41-205-12
#14
LETTER
Sasan Amanat, Mohammad Fararouei, Mostafa Dianatinasab
No abstract text is available yet for this article.
August 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868830/letter-the-effect-of-12-weeks-aerobic-resistance-and-combined-exercises-on-omentin-1-levels-and-insulin-resistance-among-type-2-diabetic-middle-aged-women-diabetes-metab-j-2017-41-205-12
#15
LETTER
https://www.readbyqxmd.com/read/28868829/factors-associated-with-improved-glycemic-control-by-direct-acting-antiviral-agent-treatment-in-egyptian-type-2-diabetes-mellitus-patients-with-chronic-hepatitis-c-genotype-4
#16
Alaaeldin Abdelsalam Dawood, Mohamed Zakarya Nooh, Ayman Abdelhaleem Elgamal
BACKGROUND: The association of chronic hepatitis C virus (HCV) infection with type 2 diabetes mellitus (T2DM) was first reported in 1994. Little is known about the effect of direct-acting antiviral agents (DAAs) on glycemic control in T2DM patients. The aim of the present study was to evaluate the factors associated with improved glycemic control (IGC) by DAA treatment in Egyptian T2DM patients with chronic HCV genotype 4 infection. METHODS: This study included 460 T2DM patients with chronic HCV genotype 4 infection...
August 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868828/in-vitro-effect-of-fatty-acids-identified-in-the-plasma-of-obese-adolescents-on-the-function-of-pancreatic-%C3%AE-cells
#17
Claudia Velasquez, Juan Sebastian Vasquez, Norman Balcazar
BACKGROUND: The increase in circulating free fatty acid (FFA) levels is a major factor that induces malfunction in pancreatic β-cells. We evaluated the effect of FFAs reconstituted according to the profile of circulating fatty acids found in obese adolescents on the viability and function of the murine insulinoma cell line (mouse insulinoma [MIN6]). METHODS: From fatty acids obtained commercially, plasma-FFA profiles of three different youth populations were reconstituted: obese with metabolic syndrome; obese without metabolic syndrome; and normal weight without metabolic syndrome...
August 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868827/depression-and-mortality-in-people-with-type-2-diabetes-mellitus-2003-to-2013-a-nationwide-population-based-cohort-study
#18
Jong Hyun Jeong, Yoo Hyun Um, Seung Hyun Ko, Jong Heon Park, Joong Yeol Park, Kyungdo Han, Kyung Soo Ko
BACKGROUND: Previous reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity of data on the mortality of depressed DM patients in Korea. METHODS: Retrospective data from January 2003 to December 2013 were collected for adult type 2 diabetes mellitus (T2DM) patients older than 30 years using the National Health Information database maintained by the Korean National Health Insurance Service (NHIS)...
August 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868826/determinants-of-long-term-durable-glycemic-control-in-new-onset-type-2-diabetes-mellitus
#19
Kyoung Jin Kim, Ju Hee Choi, Kyeong Jin Kim, Jee Hyun An, Hee Young Kim, Sin Gon Kim, Nam Hoon Kim
BACKGROUND: Long-term durable glycemic control is a difficult goal in the management of type 2 diabetes mellitus (T2DM). We evaluated the factors associated with durable glycemic control in a real clinical setting. METHODS: We retrospectively reviewed the medical records of 194 new-onset, drug-naïve patients with T2DM who were diagnosed between January 2011 and March 2013, and were followed up for >2 years. Glycemic durability was defined as the maintenance of optimal glycemic control (glycosylated hemoglobin [HbA1c] <7...
August 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28868825/effects-of-high-dose-%C3%AE-lipoic-acid-on-heart-rate-variability-of-type-2-diabetes-mellitus-patients-with-cardiac-autonomic-neuropathy-in-korea
#20
Sol Jae Lee, Su Jin Jeong, Yu Chang Lee, Yong Hoon Lee, Jung Eun Lee, Chong Hwa Kim, Kyung Wan Min, Bong Yun Cha
BACKGROUND: Diabetic cardiac autonomic neuropathy (CAN) is one of the important complications of diabetes. It is characterized by reduced heart rate variability (HRV). METHODS: In this randomized, double-blind, placebo-controlled, multicenter trial, 75 patients were randomly assigned to one of two groups. One group (n=41) received α-lipoic acid (ALA) at an oral dose of 600 mg/day for the first 12 weeks and then 1,200 mg/day for the next 12 weeks. The other group (n=34) received placebo treatment for 24 weeks...
August 2017: Diabetes & Metabolism Journal
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