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Pain Management

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https://www.readbyqxmd.com/read/28805147/a-comparison-of-transdermal-over-the-counter-lidocaine-3-6-menthol-1-25-rx-lidocaine-5-and-placebo-for-back-pain-and-arthritis
#1
Eric Castro, David Dent
AIM: Transdermal lidocaine therapy has become a gold standard as part of a treatment regimen for patients who suffer from localized pain. We compared transdermal patches: over-the-counter (OTC) lidocaine 3.6% combined with menthol 1.25%, prescription lidocaine 5% (Rx) and placebo. METHODS: In a double-blind, placebo-controlled trial, 87 patients were randomized to: OTC, Rx or placebo. RESULTS: OTC met primary end points of noninferiority compared with Rx for efficacy, side effects and quality of life...
August 14, 2017: Pain Management
https://www.readbyqxmd.com/read/28793825/controlling-acute-pain-to-improve-the-quality-of-postoperative-pain-management-an-update-from-the-european-society-of-regional-anesthesia-meeting-held-in-maastricht-september-2016
#2
Jose De Andrés, Esther Pogatzki-Zahn, Frank Huygen, Edmund Neugebauer, William Fawcett
Improvement in postoperative pain management remains a global concern with a significant unmet need for patients. This was the focus of a 'Change Pain' session at the 35th European Society of Regional Anesthesia meeting (Maastricht, September 2016). Awareness of the size and nature of the problem is important to improve postoperative pain management strategies. Optimal treatment of acute pain should aim to avoid long-term sequelae such as the development of chronic pain disorders (e.g., phantom limb pain)...
August 10, 2017: Pain Management
https://www.readbyqxmd.com/read/28762282/ketamine-miracle-drug-or-latest-fad
#3
Aneesh P Goel, Dermot P Maher, Steven P Cohen
No abstract text is available yet for this article.
August 1, 2017: Pain Management
https://www.readbyqxmd.com/read/28747087/safety-and-effectiveness-of-once-daily-hysingla-extended-release-tablets-in-patients-with-baseline-depression-or-anxiety
#4
Louise Taber, Ellie He, Steven R Ripa
AIM: Long-term safety and effectiveness of a once daily, single-entity, extended-release formulation of hydrocodone bitartrate (HYD) for the treatment of moderate to severe noncancer and nonneuropathic pain among patients with and without concurrent depression/anxiety at baseline. MATERIALS & METHODS: Post hoc analysis. RESULTS: HYD demonstrated a safety profile consistent with μ-opioid agonists: Serious adverse events in 12% patients with depression/anxiety including four deaths; 6% without depression/anxiety including one death...
July 27, 2017: Pain Management
https://www.readbyqxmd.com/read/28741429/rapid-systemic-delivery-of-zolmitriptan-using-an-adhesive-dermally-applied-microarray
#5
Donald J Kellerman, Mahmoud Ameri, Stewart J Tepper
Adhesive Dermally-Applied Microarray (ADAM) is a device for intracutaneous drug administration consisting of a 3 cm(2) disposable array of drug-coated titanium microprojections on an adhesive backing. It is applied using a low cost, reusable, handheld applicator. Microprojections penetrate the stratum corneum, delivering drug proximal to capillaries with limited likelihood of pain. The pharmacokinetics of zolmitriptan delivery using ADAM was evaluated in 20 healthy volunteers. Median tmax was <20 min, comparable to subcutaneous sumatriptan...
July 25, 2017: Pain Management
https://www.readbyqxmd.com/read/28726577/will-optogenetics-be-used-to-treat-chronic-pain-patients
#6
Hélène Beaudry, Ihab Daou, Alfredo Ribeiro-da-Silva, Philippe Séguéla
Chronic pain affects a third of the population and current treatments produce limited relief and severe side effects. An alternative strategy to decrease pain would be to directly modulate somatosensory pathways using optogenetics. Optogenetics involves the use of genetically encoded and optically active proteins, namely opsins, to control neuronal circuits. In preclinical animal models, optical silencing of peripheral nociceptors has been shown to alleviate both inflammatory and neuropathic pain. An opsin-based gene therapy to treat chronic pain patients is not ready yet, but encouraging advances have been made in optical and viral technology...
July 20, 2017: Pain Management
https://www.readbyqxmd.com/read/28699421/global-cancer-pain-management-a-systematic-review-comparing-trials-in-africa-europe-and-north-america
#7
Charles A Odonkor, Gabriel Kim, Michael Erdek
AIM: Despite the rise in cancer survivorship, few reviews have examined the quality of studies of cancer pain management and practices around the globe. With a void in trials spanning multiple geographical settings, this review evaluates the quality of cancer trials across three continents. MATERIALS & METHODS: A literature review and search of established databases was conducted to identify eligible studies. The Cochrane method, the Jadad Score and a cancer pain-specific ad hoc tool were used to evaluate quality of studies...
July 12, 2017: Pain Management
https://www.readbyqxmd.com/read/28699416/interview-with-david-tauben-university-of-washington-chief-of-the-division-of-pain-medicine
#8
David Tauben
Dr Tauben is Clinical Professor jointly appointed in the Departments of Medicine and Anesthesia & Pain Medicine, and is the Hughes M & Katherine G Blake Endowed Professor, board certified in both Internal Medicine and Pain Medicine. He is also University of Washington (UW) Director of Medical Student and Resident Education in Pain Medicine, and Medical Director of UW TelePain, a tele-video-conferencing program intended to provide innovative pain education and consultative support to a five-state northwest regional primary care providers...
July 12, 2017: Pain Management
https://www.readbyqxmd.com/read/28699410/a-patient-s-perspective-of-chronic-pain
#9
Sara G Nadler
Sara Gilbert Nadler speaks to Jade Parker, Commissioning Editor: Sara has obtained a Bachelor's Degree and Master's in social work. Her field of practice in social work has been in the field of medical social work. Sara has worked in the field of medical social work for over 20 years; her work has spanned from acute care hospitals to skilled nursing facilities. Her professional responsibilities include case management, discharge planning, financial management, counselling patients and their families in regard to their medical conditions as well as making referrals to home care agencies and other care providers if necessary...
July 12, 2017: Pain Management
https://www.readbyqxmd.com/read/28699379/what-dilemmas-do-healthcare-workers-face-looking-after-children-with-acute-pain
#10
Glyn Williams
There have been significant advances in the treatment of acute pain in children alongside increased academic interest in the field. This has led to improvements in both efficacy and safety alongside the development of multidisciplinary pain services. Despite this, however, there are still high rates of acute pain reported in children in both inpatient and outpatient settings. In this article, we discuss some of the challenges faced by healthcare workers in designing effective multidisciplinary treatment regimens, understanding the implications for long-term pain and pain processing of acute pain and analgesic interventions as well as ongoing issues around research, education and resource...
July 12, 2017: Pain Management
https://www.readbyqxmd.com/read/28699374/shared-medical-appointments-for-managing-pain-in-primary-care-settings
#11
Jonathan Coates, Fraser Gething, Mark I Johnson
No abstract text is available yet for this article.
July 12, 2017: Pain Management
https://www.readbyqxmd.com/read/28589749/safety-of-parecoxib-when-used-for-more-than-3-days-for-the-management-of-postoperative-pain
#12
Margaret Noyes Essex, Raymond Cheung, Chunming Li, Li Xie
AIM: To assess parecoxib safety when used for >3 days for postoperative pain management. METHODS: Treatment-emergent adverse event (TEAE) occurrence after day 3 was examined in a pooled analysis of three placebo-controlled trials of parecoxib following general or gynecologic surgery, or total hip arthroplasty. A total of 358 patients received parecoxib, and 318 placebo. RESULTS: Mean treatment duration was similar between treatment groups...
June 7, 2017: Pain Management
https://www.readbyqxmd.com/read/28699380/addressing-the-barriers-related-with-opioid-therapy-for-management-of-chronic-pain-in-india
#13
Gur Prasad Dureja, Paramanand N Jain, Muralidhar Joshi, Ashok Saxena, Gautam Das, Jaishid Ahdal, Prashant Narang
India has a high prevalence of chronic disorders which may be associated with persistent pain. Despite the availability of multiple treatment options, chronic pain is largely untreated and contributes to disability and mortality. Medical consumption of opioids remains low due to various barriers that prevent access to opioids for patients and healthcare practitioners. Stringent regulatory provisions outlined in the Narcotic Drugs and Psychotropic Substances Act (1985) have been major deterrents to adequate opioid use...
July 2017: Pain Management
https://www.readbyqxmd.com/read/28326950/efficacy-of-the-topical-5-lidocaine-medicated-plaster-in-the-treatment-of-chronic-post-thoracotomy-neuropathic-pain
#14
Pasquale Sansone, Maria Beatrice Passavanti, Alfonso Fiorelli, Caterina Aurilio, Umberto Colella, Lorenzo De Nardis, Valerio Donatiello, Vincenzo Pota, Maria Caterina Pace
AIM: To assess the efficacy of the topical 5% lidocaine medicated plaster (Versatis(®), Grünenthal GmbH, Aachen, Germany) in patients with post-thoracotomy neuropathic pain. PATIENTS & METHODS: Patients were randomized to receive the topical 5% lidocaine medicated plaster (n = 33) or non-medicated placebo plasters (n = 30) for 12 h every day for 8 weeks. Laser-evoked potentials (LEPs) were measured, and various questionnaires/scales completed. RESULTS: Numeric Rating Scale pain scores improved significantly (p < 0...
May 2017: Pain Management
https://www.readbyqxmd.com/read/28152647/exercise-interventions-for-juvenile-fibromyalgia-current-state-and-recent-advancements
#15
William R Black, Susmita Kashikar-Zuck
No abstract text is available yet for this article.
May 2017: Pain Management
https://www.readbyqxmd.com/read/28147900/reflective-practice-providing-safe-quality-patient-centered-pain-management
#16
Gwen Sherwood, Jeanette McNeill
Effective pain management continues to baffle clinicians in spite of numerous evidence-based guidelines and standards, focused clinical interventions and standardized assessments. Reflective practice is a mindful approach to practice that grounds clinicians in the moment with the individual patient to ask questions and then to listen to the patient's message about their pain experience. Reflective practice helps meld theoretical knowledge with lessons from experience to rethink mechanistic responses to patient pain...
May 2017: Pain Management
https://www.readbyqxmd.com/read/28135936/toward-an-etiology-based-management-of-trigeminal-neuralgia
#17
Turo J Nurmikko
No abstract text is available yet for this article.
May 2017: Pain Management
https://www.readbyqxmd.com/read/28103764/multimodal-pediatric-pain-management-part-2
#18
Stefan J Friedrichsdorf
Dr Stefan Friedrichsdorf speaks to Commissioning Editor Jade Parker: Stefan Friedrichsdorf, MD, is medical director of the Department of Pain Medicine, Palliative Care and Integrative Medicine at Children's Hospitals and Clinics of Minnesota in Minneapolis/St Paul, MN, USA, home to one of the largest and most comprehensive programs of its kind in the country. The pain and palliative care program is devoted to control acute, chronic/complex and procedural pain for inpatients and outpatients in close collaboration with all pediatric subspecialties at Children's Minnesota...
May 2017: Pain Management
https://www.readbyqxmd.com/read/28073312/female-chronic-pelvic-pain-the-journey-to-diagnosis-and-beyond
#19
Hannah Twiddy, Alison Bradshaw, Rajiv Chawla, Selina Johnson, Natalie Lane
No abstract text is available yet for this article.
May 2017: Pain Management
https://www.readbyqxmd.com/read/27882843/somatic-symptom-disorder-treated-with-electroconvulsive-therapy
#20
Anna Borisovskaya, Jay Alan Augsburger
Somatic symptom disorder (SSD) is a challenging condition to treat with chronic pain, a common and disabling symptom. We present a patient who received electroconvulsive therapy (ECT) for SSD with significant improvement in pain and gastrointestinal symptoms. We also present a brief literature review of similar cases treated with ECT. Preliminary evidence suggests that ECT should be considered for treatment of SSD comorbid with major depressive disorder, when standard treatments fail. Further research is needed to clarify whether ECT can be used for SSD without associated depression...
May 2017: Pain Management
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