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Pain Management

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https://www.readbyqxmd.com/read/29774774/undertreatment-of-pain-and-low-use-of-opioids-in-latin-america
#1
César Amescua García, Joao Batista Santos Garcia, María Del Rosario Berenguel Cook, Frantz Colimon, José Alberto Flores Cantisani, Carlos Guerrero, María Del Rocío Guillén Núnez, John Jairo Hernández Castro, Durval Campos Kraychete, Argelia Lara-Solares, Osvandré Lech, María Antonieta Rico Pazos, Manuel Sempértegui Gallegos, Lizandra Pattaro Marcondes
Pain is highly prevalent among the adult Latin American population. However, many patients with moderate to severe pain do not have access to effective pain management with opioids due to limited access to healthcare, overuse of nonopioid analgesics, regulatory barriers and lack of appropriate information about opioids. There is scarce training on use of opioids among physicians and other healthcare providers, which leads to misconceptions, mainly related to a fear of prescribing opioids. Although opioids are safe and effective drugs for the treatment of moderate to severe chronic pain, the use of opioids in Latin American nations is clearly below standards compared with developed countries...
May 18, 2018: Pain Management
https://www.readbyqxmd.com/read/29722608/lysergic-acid-diethylamide-and-psilocybin-for-the-management-of-patients-with-persistent-pain-a-potential-role
#2
Andy Whelan, Mark I Johnson
Recently, there has been interest in lysergic acid diethylamide (LSD) and psilocybin for depression, anxiety and fear of death in terminal illness. The aim of this review is to discuss the potential use of LSD and psilocybin for patients with persistent pain. LSD and psilocybin are 5-hydroxytryptamine receptor agonists and may interact with nociceptive and antinociceptive processing. Tentative evidence from a systematic review suggests that LSD (7 studies, 323 participants) and psilocybin (3 studies, 92 participants) may be beneficial for depression and anxiety associated with distress in life-threatening diseases...
May 3, 2018: Pain Management
https://www.readbyqxmd.com/read/29722606/effect-of-virtual-reality-headset-for-pediatric-fear-and-pain-distraction-during-immunization
#3
Rudnick Chad, Sulaiman Emaan, Orden Jillian
AIM: Fear of needles is a well-known phobia among children and adults. This study presents the rationale, feasibility and results of a pilot study applying a virtual reality (VR) headset as a fear reduction and pain distraction during immunizations. PATIENTS & METHODS: 17 subjects and 17 parents rated their fear and pain level pre- and postimmunization using Wong-Baker pain scale and McMurtry children's fear scale. Immunization was provided, while subject was wearing a VR headset...
May 3, 2018: Pain Management
https://www.readbyqxmd.com/read/29722603/a-keynesian-demand-reduction-approach-to-the-opioid-epidemic
#4
Heath McAnally
No abstract text is available yet for this article.
May 3, 2018: Pain Management
https://www.readbyqxmd.com/read/29722602/low-level-laser-therapy-and-interferential-current-in-patients-with-knee-osteoarthritis-a-randomized-controlled-trial-protocol
#5
Renata Alqualo-Costa, Gustavo R Thomé, Mônica R Perracini, Richard E Liebano
The aim of this study is to investigate the effects of low-level laser therapy and interferential current (IFC) on pain intensity, central sensitization, muscle strength and functional capacity in patients with knee osteoarthritis. Participants will be patients aged between 50 and 80 years, with knee osteoarthritis, pain intensity ranging from 3 to 8 points (0-10 scale), Lequesne Algofunctional Index ranging from 5 to 15 points, and Kellgren & Lawrence grade ≥2. A total of 168 patients will be randomly allocated into four groups as follows: active IFC + laser sham (G1), IFC sham + active laser (G2), active IFC + laser (G3) and IFC + laser sham (G4)...
May 3, 2018: Pain Management
https://www.readbyqxmd.com/read/29683378/pharmacokinetic-properties-of-intranasal-and-injectable-formulations-of-naloxone-for-community-use-a-systematic-review
#6
Shawn A Ryan, Robert B Dunne
AIM: To assess the pharmacokinetic properties of community-use formulations of naloxone for emergency treatment of opioid overdose. METHODS: Systematic literature review based on searches of established databases and congress archives. RESULTS: Seven studies met inclusion criteria: two of US FDA-approved intramuscular (im.)/subcutaneous (sc.) auto-injectors, one of an FDA-approved intranasal spray, two of unapproved intranasal kits (syringe with atomizer attachment) and two of intranasal products in development...
April 23, 2018: Pain Management
https://www.readbyqxmd.com/read/29671676/effects-of-gabapentin-pregabalin-and-gastroretentive-gabapentin-on-simulated-driving-daytime-sedation-and-cognition
#7
Peter Schmidt, Srinivas Rao
AIM: Randomized Phase I study examining the effects of gabapentinoids gabapentin, pregabalin and gastroretentive gabapentin on simulated driving performance, sedation and cognitive function in healthy volunteers (n = 32). METHODS: Driving attentiveness, sleepiness and cognition were evaluated prior to subjects receiving study doses. Blood samples were collected during each treatment. RESULTS: Subjects receiving gastroretentive gabapentin showed less change in variation in lateral lane position (p = 0...
April 19, 2018: Pain Management
https://www.readbyqxmd.com/read/29667869/evaluation-of-an-innovative-spinal-cord-stimulator-platform-for-the-treatment-of-chronic-pain
#8
Christopher Davies, Carlee Komoroski, Lance Roy
Spinal cord stimulation (SCS) is an ever-evolving therapy for the treatment of chronic pain. Currently, there are four main companies offering a variety of options for SCS. The Intellis™ system is the latest offering from Medtronic (MN, USA). Intellis offers the smallest implantable SCS pulse generator available and is capable of multiple different modes of stimulation, some of which can be run simultaneously. With an intrinsic accelerometer, the device is capable of sensing various patient positions and can automatically adjust stimulation intensity...
April 18, 2018: Pain Management
https://www.readbyqxmd.com/read/29667859/prescribing-naloxone-for-opioid-overdose-intervention
#9
Robert B Dunne
To provide an update on prescription of naloxone as a harm-reduction strategy, PubMed was searched to identify publications relevant to naloxone prescribing for reversal of opioid overdose. Opportunities now exist to expand naloxone use, although evidence suggests these are often missed or underexploited. The US FDA has approved an intranasal naloxone spray and an autoinjector naloxone formulation for community use. Effective use of naloxone in community settings requires screening to identify patients at risk of opioid overdose, discussing naloxone use with patients and their relatives, and providing appropriate training...
April 18, 2018: Pain Management
https://www.readbyqxmd.com/read/29468939/objectively-measuring-pain-using-facial-expression-is-the-technology-finally-ready
#10
Thomas Richard Dawes, Ben Eden-Green, Claire Rosten, Julian Giles, Ricardo Governo, Francesca Marcelline, Charles Nduka
Currently, clinicians observe pain-related behaviors and use patient self-report measures in order to determine pain severity. This paper reviews the evidence when facial expression is used as a measure of pain. We review the literature reporting the relevance of facial expression as a diagnostic measure, which facial movements are indicative of pain, and whether such movements can be reliably used to measure pain. We conclude that although the technology for objective pain measurement is not yet ready for use in clinical settings, the potential benefits to patients in improved pain management, combined with the advances being made in sensor technology and artificial intelligence, provide opportunities for research and innovation...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29468928/the-work-of-childhood-understanding-school-functioning-in-youth-with-chronic-pain
#11
Kailyn Jones, David Nordstokke, Gabrielle Wilcox, Meadow Schroeder, Melanie Noel
School is often cited as the 'work of childhood' and serves as an important site for child and adolescent development. Frequent school absences in children and adolescents with chronic pain are well documented; however, variables that may explain school impairment are not understood. The potential consequences of school impairment are extensive, as these children and adolescents are at great risk for achieving poor grades and sometimes require full-time homebound instruction. This, in turn, can have adverse effects on occupational and social functioning well into adulthood...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29451431/study-protocol-of-hypoalgesic-effects-of-low-frequency-and-burst-modulated-alternating-currents-on-healthy-individuals
#12
Érika Patrícia Rampazo da Silva, Viviane Ribeiro da Silva, Anabelly Sato Bernardes, Fabio Massao Matuzawa, Richard Eloin Liebano
The aim of the study will be to compare different types of analgesic electrical currents in relation to the pressure pain threshold and sensory comfort in healthy individuals. A total of 100 individuals will be randomly assigned to four groups: transcutaneous electrical nerve stimulation, interferential current, Aussie current or placebo. The electrical stimulation will be administered with a strong level for 30 min and to the placebo group, the electrodes will be positioned while the equipment will remain switched off...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29451429/perceived-injustice-in-chronic-pain-an-examination-through-the-lens-of-predictive-processing
#13
Daniel A Bissell, Maisa S Ziadni, John A Sturgeon
Chronic pain conditions have been shown to be exacerbated by psychological factors, and a better understanding of these factors can inform clinical practice and improve the efficacy of interventions. The current paper investigates perceived injustice, a novel psychosocial construct, within a framework influenced by the tenets of predictive processing. The proposed conceptual model derived from tenets of predictive processing yields a single hierarchical self-reconfiguring system driven by prediction, which accounts for a wide range of human experiences such as perception, behavior, learning and emotion...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29451426/prioritizing-pediatric-chronic-pain-and-comprehensive-pain-treatment-in-the-context-of-the-opioid-epidemic
#14
Sarah R Martin, Lonnie K Zeltzer
No abstract text is available yet for this article.
March 2018: Pain Management
https://www.readbyqxmd.com/read/29451418/patient-narratives-in-yelp-reviews-offer-insight-into-opioid-experiences-and-the-challenges-of-pain-management
#15
Rachel L Graves, Jesse Goldshear, Jeanmarie Perrone, Lyle Ungar, Elissa Klinger, Zachary F Meisel, Raina M Merchant
AIM: To characterize Yelp reviews about pain management and opioids. METHODS: We manually coded and applied natural language processing to 836 Yelp reviews of US hospitals mentioning an opioid medication. RESULTS: Yelp reviews by patients and caregivers describing experiences with pain management and opioids had lower ratings compared with other reviews. Negative descriptions of pain management and opioid-related experiences were more commonly described than positive experiences, and the number of themes they reflected was more diverse...
March 1, 2018: Pain Management
https://www.readbyqxmd.com/read/29381110/qualities-of-sore-throat-index-quasti-measuring-descriptors-of-sore-throat-in-a-randomized-placebo-controlled-trial
#16
Bernard Schachtel, Adrian Shephard, Emily Schachtel, Mary Beth Lorton, Tim Shea, Sue Aspley
AIM: Patients with pharyngitis often describe various sensory, affective and evaluative pain qualities. Using an 11-word/phrase index, the Qualities of Sore Throat Index (QuaSTI), we characterized throat symptoms and evaluated changes in a randomized controlled trial (NCT01986361). MATERIALS & METHODS: Patients received a single flurbiprofen 8.75 mg (n = 101) or placebo (n = 21) lozenge and rated throat soreness at baseline and regular intervals over 3 h, and the QuaSTI at baseline, 1, 2 and 3 h post-treatment...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29376761/meaningful-relief-with-flurbiprofen-8-75-mg-spray-in-patients-with-sore-throat-due-to-upper-respiratory-tract-infection
#17
Ferdinandus de Looze, Marc Russo, Mark Bloch, Barney Montgomery, Adrian Shephard, Robert DeVito
AIM: Evaluate the efficacy of flurbiprofen 8.75 mg spray for sore throat relief. PATIENTS & METHODS: Randomized, double-blind study in adults with sore throat due to upper respiratory tract infection who took flurbiprofen (n = 249) or placebo spray (n = 256). Pain relief was assessed using the Sore Throat Relief Rating Scale. RESULTS: Flurbiprofen spray provided significantly greater relief versus placebo from 20 min to 6 h (p < 0...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29251544/consensus-recommendations-for-managing-osteoarthritic-pain-with-topical-nsaids-in-asia-pacific
#18
Bonifacio S Rafanan, Benedict F Valdecañas, Boon Ping Lim, Anan Malairungsakul, Warat Tassanawipas, Chen Shiyi, Lung Fung Tse, Tuan Khanh Luong
Osteoarthritis prevalence is expected to increase markedly in the Asia-Pacific region due to rapid population aging. Identifying effective and safe therapeutic options to manage osteoarthritic pain is viewed as a priority. The Asia-Pacific Experts on Topical Analgesics Advisory Board developed consensus statements for use of topical NSAIDs in musculoskeletal pain. Evidence supporting these statements in osteoarthritic pain was reviewed. Best available evidence indicates that topical NSAIDs have a moderate effect on relief of osteoarthritic pain, comparable to that of oral NSAIDs but with a better risk-to-benefit ratio...
March 2018: Pain Management
https://www.readbyqxmd.com/read/29210330/subcutaneous-local-anesthetic-infusion-could-eliminate-use-of-epidural-analgesia-after-the-nuss-procedure
#19
Sandra K Kabagambe, Laura F Goodman, Y Julia Chen, Benjamin A Keller, James C Becker, Gary W Raff, Rebecca A Stark, Jacob T Stephenson, Amy Rahm, Diana L Farmer, Shinjiro Hirose
AIM: To compare outcomes of continuous subcutaneous infusion of local anesthetic and epidural analgesia following the Nuss procedure. PATIENTS & METHODS: A retrospective chart review compared patients managed with subcutaneous local anesthetic infusion (n = 12) versus thoracic epidural (n = 19) following the Nuss procedure from March 2013 to June 2015. RESULTS: There was no difference in hospital length of stay or days on intravenous narcotics...
January 2018: Pain Management
https://www.readbyqxmd.com/read/29199542/medication-use-among-pediatric-patients-with-chronic-musculoskeletal-pain-syndromes-at-initial-pain-clinic-evaluation
#20
Jessica W Guite, David D Sherry, Esther W Jarvis, Margaret O Lewen, Sarosh Khan, Francis Wickham Kraemer
AIM: To characterize medication use by adolescents with chronic musculoskeletal pain syndromes before an initial multidisciplinary clinic visit. PATIENTS & METHODS: A cross-sectional sample of 120 adolescents and parents reported on standardized assessment measures, with medication use data extracted from the medical chart and categorized. RESULTS: On average, 3.2 medications were reported; 70% used more than one pain-specific medication including opioids (17%), nonopioids (31%), psychotropics/neuropathics (45%) and other medications (13%)...
January 2018: Pain Management
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