journal
MENU ▼
Read by QxMD icon Read
search

Frontiers in Endocrinology

journal
https://www.readbyqxmd.com/read/28919880/non-mammalian-vertebrates-distinct-models-to-assess-the-role-of-ion-gradients-in-energy-expenditure
#1
REVIEW
Caroline E Geisler, Kyle P Kentch, Benjamin J Renquist
Animals store metabolic energy as electrochemical gradients. At least 50% of mammalian energy is expended to maintain electrochemical gradients across the inner mitochondrial membrane (H(+)), the sarcoplasmic reticulum (Ca(++)), and the plasma membrane (Na(+)/K(+)). The potential energy of these gradients can be used to perform work (e.g., transport molecules, stimulate contraction, and release hormones) or can be released as heat. Because ectothermic species adapt their body temperature to the environment, they are not constrained by energetic demands that are required to maintain a constant body temperature...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28912754/the-gambian-bone-and-muscle-ageing-study-baseline-data-from-a-prospective-observational-african-sub-saharan-study
#2
Ayse Zengin, Anthony J Fulford, Yankuba Sawo, Landing M Jarjou, Inez Schoenmakers, Gail Goldberg, Ann Prentice, Kate A Ward
The Gambian Bone and Muscle Ageing Study is a prospective observational study investigating bone and muscle ageing in men and women from a poor, subsistence farming community of The Gambia, West Africa. Musculoskeletal diseases, including osteoporosis and sarcopenia, form a major part of the current global non-communicable disease burden. By 2050, the vast majority of the world's ageing population will live in low- and middle-income countries with an estimated two-fold rise in osteoporotic fracture. The study design was to characterise change in bone and muscle outcomes and to identify possible preventative strategies for fracture and sarcopenia in the increasing ageing population...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28912753/food-addiction-in-patients-with-newly-diagnosed-type-2-diabetes-in-northeast-china
#3
Fan Yang, Aihua Liu, Yongze Li, Yaxin Lai, Guixia Wang, Chenglin Sun, Guang Sun, Zhongyan Shan, Weiping Teng
AIM: The aim of the study was to explore the prevalence of food addiction (FA) in individuals with newly diagnosed type 2 diabetes mellitus (T2DM) in China and to analyze risk factors of FA. METHODS: A total of 624 subjects [312 individuals with newly diagnosed T2DM, 312 age-matched and body mass index (BMI)-matched healthy participants] were recruited. All participants were asked to complete the Yale Food Addiction Scale (YFAS) and received physical and lab examinations...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28912752/disparities-in-cardiovascular-disease-and-type-2-diabetes-risk-factors-in-blacks-and-whites-dissecting-racial-paradox-of-metabolic-syndrome
#4
REVIEW
Kwame Osei, Trudy Gaillard
Cardiovascular diseases (CVD) remain as the leading cause of mortality in the western world and have become a major health threat for developing countries. There are several risk factors that account for the CVD and the associated mortality. These include genetics, type 2 diabetes (T2DM), obesity, physical inactivity, hypertension, and abnormal lipids and lipoproteins. The constellation of these risk factors has been termed metabolic syndrome (MetS). MetS varies among racial and ethnic populations. Thus, race and ethnicity account for some of the differences in the MetS and the associated CVD and T2DM...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28900415/perinatal-western-diet-consumption-leads-to-profound-plasticity-and-gabaergic-phenotype-changes-within-hypothalamus-and-reward-pathway-from-birth-to-sexual-maturity-in-rat
#5
Julie Paradis, Pierre Boureau, Thomas Moyon, Sophie Nicklaus, Patricia Parnet, Vincent Paillé
Perinatal maternal consumption of energy dense food increases the risk of obesity in children. This is associated with an overconsumption of palatable food that is consumed for its hedonic property. The underlying mechanism that links perinatal maternal diet and offspring preference for fat is still poorly understood. In this study, we aim at studying the influence of maternal high-fat/high-sugar diet feeding [western diet (WD)] during gestation and lactation on the reward pathways controlling feeding in the rat offspring from birth to sexual maturity...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28894436/serum-thyroid-hormone-antibodies-are-frequent-in-patients-with-polyglandular-autoimmune-syndrome-type-3-particularly-in-those-who-require-thyroxine-treatment
#6
Roberto Vita, Maria Giulia Santaguida, Camilla Virili, Maria Segni, Marina Galletti, Mattia Mandolfino, Flavia Di Bari, Marco Centanni, Salvatore Benvenga
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison's disease and hypoparathyroidism. We evaluated the prevalence and repertoire of thyroid hormones antibodies (THAb) in PAS-3 patients. Using a radioimmunoprecipation technique, we measured THAb (T3IgM, T3IgG, T4IgM, and T4IgG) in 107 PAS-3 patients and 88 controls (patients with AITD without any NTAID). Based on the selective coexistence of AITD with one NTAID (chronic autoimmune gastritis, non-segmental vitiligo or celiac disease), patients were divided into group 1 (chronic autoimmune gastritis positive, n = 64), group 2 (non-segmental vitiligo positive, n = 24), and group 3 (celiac disease positive, n = 15)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28890710/commentary-thyrotropin-stimulates-differentiation-not-proliferation-of-normal-human-thyrocytes-in-culture
#7
COMMENT
Aglaia Kyrilli, Sabine Paternot, Françoise Miot, Bernard Corvilain, Gilbert Vassart, Pierre P Roger, Jacques E Dumont
No abstract text is available yet for this article.
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28890709/editorial-neuropeptides-and-behavior-from-motivation-to-psychopathology
#8
EDITORIAL
Deborah Suchecki, Carol F Elias
No abstract text is available yet for this article.
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28883808/grass-carp-follisatin-molecular-cloning-functional-characterization-dopamine-d1-regulation-at-pituitary-level-and-implication-in-growth-hormone-regulation
#9
Roger S K Fung, Bai Jin, Mulan He, Karen W Y Yuen, Anderson O L Wong
Activin is involved in pituitary hormone regulation and its pituitary actions can be nullified by local production of its binding protein follistatin. In our recent study with grass carp, local release of growth hormone (GH) was shown to induce activin expression at pituitary level, which in turn could exert an intrapituitary feedback to inhibit GH synthesis and secretion. To further examine the activin/follistatin system in the carp pituitary, grass carp follistatin was cloned and confirmed to be single-copy gene widely expressed at tissue level...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28878739/precocious-puberty-or-premature-thelarche-analysis-of-a-large-patient-series-in-a-single-tertiary-center-with-special-emphasis-on-6-to-8-year-old-girls
#10
Tero Varimo, Heta Huttunen, Päivi Johanna Miettinen, Laura Kariola, Johanna Hietamäki, Annika Tarkkanen, Matti Hero, Taneli Raivio
INTRODUCTION: We describe the etiology, MRI findings, and growth patterns in girls who had presented with signs of precocious puberty (PP), i.e., premature breast development or early menarche. Special attention was paid to the diagnostic findings in 6- to 8-year-olds. MATERIALS AND METHODS: We reviewed the medical records of 149 girls (aged 0.7-10.3 years) who had been evaluated for PP in the Helsinki University Hospital between 2001 and 2014. RESULTS: In 6- to 8-year-old girls, PP was most frequently caused by idiopathic gonadotropin-releasing hormone (GnRH)-dependent PP (60%) and premature thelarche (PT; 39%)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28878738/overlooked-mechanisms-in-type-1-diabetes-etiology-how-unique-costimulatory-molecules-contribute-to-diabetogenesis
#11
REVIEW
David H Wagner
Type 1 Diabetes (T1D) develops when immune cells invade the pancreatic islets resulting in loss of insulin production in beta cells. T cells have been proven to be central players in that process. What is surprising, however, is that classic mechanisms of tolerance cannot explain diabetogenesis; alternate mechanisms must now be considered. T cell receptor (TCR) revision is the process whereby T cells in the periphery alter TCR expression, outside the safety-net of thymic selection pressures. This process results in an expanded T cell repertoire, capable of responding to a universe of pathogens, but limitations are that increased risk for autoimmune disease development occurs...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28878737/conservation-of-three-dimensional-helix-loop-helix-structure-through-the-vertebrate-lineage-reopens-the-cold-case-of-gonadotropin-releasing-hormone-associated-peptide
#12
Daniela I Pérez Sirkin, Anne-Gaëlle Lafont, Nédia Kamech, Gustavo M Somoza, Paula G Vissio, Sylvie Dufour
GnRH-associated peptide (GAP) is the C-terminal portion of the gonadotropin-releasing hormone (GnRH) preprohormone. Although it was reported in mammals that GAP may act as a prolactin-inhibiting factor and can be co-secreted with GnRH into the hypophyseal portal blood, GAP has been practically out of the research circuit for about 20 years. Comparative studies highlighted the low conservation of GAP primary amino acid sequences among vertebrates, contributing to consider that this peptide only participates in the folding or carrying process of GnRH...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28878736/commentary-torpor-the-rise-and-fall-of-3-monoiodothyronamine-from-brain-to-gut-from-gut-to-brain
#13
COMMENT
Annunziatina Laurino, Laura Raimondi
No abstract text is available yet for this article.
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28878735/microrna-regulation-of-brown-adipogenesis-and-thermogenic-energy-expenditure
#14
REVIEW
Farnaz Shamsi, Hongbin Zhang, Yu-Hua Tseng
Obesity, diabetes, and associated metabolic diseases have become global epidemics. Obesity results from excess accumulation of white fat, while brown and its related beige fat function to dissipate energy as heat, thus counteracting obesity and its related metabolic disorders. Understanding the regulatory mechanisms for both white and brown adipogenesis provides new insights for prevention and treatment of these metabolic diseases. In addition to traditional gene transcription and translation, microRNA (miRNA) represents a new layer of regulatory mechanism in many biological processes and has attracted a great deal of research interests in exploring their roles in physiological and pathophysiological conditions...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28871240/in-vivo-and-in-vitro-analysis-in-coronary-artery-disease-related-to-type-2-diabetes
#15
Teresa Infante, Ernesto Forte, Marco Aiello, Marco Salvatore, Carlo Cavaliere
AIM: The leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (DM) is coronary artery disease (CAD), a condition often asymptomatic but severe in these patients. Although glucose metabolism impairment and oxidative stress are known actors in the endothelial dysfunction/remodeling that occurs in diabetic patients, the relationship between cardiovascular disorders and DM is not fully understood. We have performed both an in vivo imaging and in vitro molecular analysis to investigate diabetic-specific CAD alterations...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28871239/arginine-vasopressin-effects-on-subjective-judgments-and-neural-responses-to-same-and-other-sex-faces-in-men-and-women
#16
James K Rilling, Ting Li, Xiangchuan Chen, Pritam Gautam, Ebrahim Haroon, Richmond R Thompson
Arginine vasopressin (AVP) influences social and emotional behaviors across a wide range of species. In humans, intranasal AVP has been previously shown to alter physiological responses to and subjective judgments of same-sex faces in both men and women. The present study attempted to elucidate the neural mechanism for these effects by randomizing 40 healthy men and 40 healthy women to treatment with either 40 IU intranasal AVP or a saline placebo approximately 30 min before imaging their brain function with fMRI as they viewed same and other-sex faces...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28868048/extracellular-vesicles-from-adipose-tissue-a-potential-role-in-obesity-and-type-2-diabetes
#17
REVIEW
Xuan Gao, Carlos Salomon, Dilys J Freeman
Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae, such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride can lead to adipose tissue inflammation and spillover of fatty acids from this tissue and accumulation of fatty acids as lipid droplets in ectopic sites, such as liver and muscle. Extracellular vesicles (EVs) are released from adipocytes and have been proposed to be involved in adipocyte/macrophage cross talk and to affect insulin signaling and transforming growth factor β expression in liver cells leading to metabolic disease...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28861044/diabetic-neuropathy-evaluated-by-a-novel-device-sural-nerve-conduction-is-associated-with-glycemic-control-and-ankle-brachial-pressure-index-in-japanese-patients-with-diabetes
#18
Hidetaka Hamasaki, Yasuteru Hamasaki
BACKGROUND: Currently, no international diagnostic criteria for diabetic neuropathy (DN) have been established. Recently, a novel point-of-care sural nerve conduction device has been developed. We aimed to investigate associations between DN and clinical parameters related to the development and progression of DN by using this novel device. METHODS: We conducted a retrospective observational study in patients with diabetes whose sural nerve functions were measured using DPN Check between January 2015 and October 2016...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28861043/editorial-circadian-rhythms-and-metabolism
#19
EDITORIAL
Etienne Challet, Andries Kalsbeek
No abstract text is available yet for this article.
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28861042/3-iodothyronamine-a-novel-endogenous-modulator-of-transient-receptor-potential-melastatin-8
#20
REVIEW
Noushafarin Khajavi, Stefan Mergler, Heike Biebermann
The decarboxylated and deiodinated thyroid hormone (TH) derivative, 3-iodothyronamine (3-T1AM), is suggested to be involved in energy metabolism and thermoregulation. G protein-coupled receptors (GPCRs) are known as the main targets for 3-T1AM; however, transient receptor potential channels (TRPs) were also recently identified as new targets of 3-T1AM. This article reviews the current knowledge of a putative novel role of 3-T1AM in the modulation of TRPs. Specifically, the TRP melastatin 8 (TRPM8) was identified as a target of 3-T1AM in different cell types including neoplastic cells, whereby 3-T1AM significantly increased cytosolic Ca(2+) through TRPM8 activation...
2017: Frontiers in Endocrinology
journal
journal
43491
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"