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Indian Journal of Endocrinology and Metabolism

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https://www.readbyqxmd.com/read/29285466/gestational-diabetes-mellitus-training-a-well-grounded-approach-for-safeguarding-two-generations
#1
Ranjit Unnikrishnan, Suganthi Jaganathan, Pallavi Wadhwani, Sandeep Bhalla, Pushkar Kumar, Sourabh Sinha, Neerja Bhatla, Padmalatha Venkatram, Kusagradhi Ghosh, Ambrish Mittal, Dorairaj Prabhakaran, Nikhil Tandon, Viswanathan Mohan, Uma Ram
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285465/primary-antiphospholipid-antibody-syndrome-presenting-as-unilateral-adrenal-hemorrhage
#2
Shruti Khare, Hardik Patel, Gargey Sutaria, Reena Sharma
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285464/preservation-of-thyrotroph-function-in-sheehan-s-syndrome
#3
Bashir Ahmad Laway, Sajad Sumji
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285463/karma-and-diabetes-mellitus
#4
Jan Brož
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285462/leptin-receptors-can-be-an-alternative-target-for-new-anti-hypertensive-drug-development
#5
Mridula Ramkumar, S K Kanthlal
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285461/sulfonylureas-scoring-beyond-start-study
#6
Altamash Shaikh
No abstract text is available yet for this article.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285460/prevalence-of-pharamcologically-treated-diabetes-in-term-pregnancies-in-haryana-india
#7
Bharti Kalra, Sanjay Kalra, Meenu Choudhary, Meenakshi Thakral
Gestational diabetes mellitus (GDM) is common in pregnancy. Epidemiological studies have described the prevalence of GDM in the antenatal period, but do not assess the number of women who require pharmacological therapy at term. This information is important for obstetric care providers and health planners. We reviewed indoor charts of all women admitted for delivery at a maternity center in Karnal, Haryana, India. Of the 569 participants, 0.87% had preexisting diabetes, while 1.93% were being treated with drugs for GDM (0...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285459/the-heart-of-the-matter-cardiac-manifestations-of-endocrine-disease
#8
REVIEW
Aditya John Binu, Kripa Elizabeth Cherian, Nitin Kapoor, Sujith Thomas Chacko, Oommen George, Thomas Vizhalil Paul
Endocrine disorders manifest as a disturbance in the milieu of multiple organ systems. The cardiovascular system may be directly affected or alter its function to maintain the state of homeostasis. In this article, we aim to review the pathophysiology, diagnosis, clinical features and management of cardiac manifestations of various endocrine disorders.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285458/sodium-glucose-cotransporter-2-inhibitors-moving-beyond-the-glycemic-treatment-goal
#9
REVIEW
Vishal Gupta, William Canovatchel, B N Lokesh, Ravi Santani, Nishant Garodia
Revelations of the multifactorial pathogenesis of type 2 diabetes mellitus (T2DM) that extend beyond the role of insulin and glucose utilization have been crucial in redefining the treatment paradigm. The focus of treatment is currently directed towards achieving wide-ranging targets encompassing the management of cardiovascular comorbidities that have been evidenced as indispensable aspects of T2DM. While most currently prescribed antihyperglycemic agents have little or no effect on reducing cardiovascular risks, some have been associated with undesirable effects on common risk factors such as weight gain and cardiovascular sequelae...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285457/osteogenesis-imperfecta
#10
REVIEW
Justin Easow Sam, Mala Dharmalingam
Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI-XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts. The mainstay of treatment is bisphosphonate therapy. The prognosis is variable.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285456/gemigliptin-newer-promising-gliptin-for-type-2-diabetes-mellitus
#11
REVIEW
Manish Gutch, Abhay Joshi, Sukriti Kumar, Avinash Agarwal, Rajendra Kumar Pahan, Syed Mohd Razi
The dipeptidyl peptidase-4 (DPP-4) inhibitors have facilitated the management of type 2 diabetes mellitus (T2DM) owing to their superior efficacy and safety with low incidence of adverse effects. Gemigliptin is a new member of this family of drugs, and studies have revealed certain advantages of gemigliptin use compared to its previous congeners. Besides, this drug has also been studied for the treatment of T2DM as monotherapy, in combination with metformin or other oral antidiabetic drugs and in T2DM with moderate-to-severe renal failure...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285455/bhagavad-gita-for-the-physician
#12
REVIEW
Sanjay Kalra, Ameya Joshi, Bharti Kalra, Vivekanand G Shanbhag, Rajib Bhattacharya, Komal Verma, Manash P Baruah, Rakesh Sahay, Sarita Bajaj, Navneet Agrawal, Ashim Chakraborty, Yatan Pal Singh Balhara, Sandeep Chaudhary, Deepak Khandelwal, Sameer Aggarwal, Nanik Ram, Jubbin Jacob, Sandeep Julka, Gagan Priya, Shelley Bhattacharya, Komal Dalal
This communication presents verses from the Bhagavad Gita which help define a good clinician's skills and behavior. Using the teachings of Lord Krishna, these curated verses suggest three essential skills that a physician must possess: Excellent knowledge, equanimity, and emotional attributes. Three good behaviors are listed (Pro-work ethics, Patient-centered care, and Preceptive leadership) and supported by thoughts written in the Gita.
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285454/hypothyroidism-and-depression-are-cytokines-the-link
#13
Parimal S Tayde, Nikhil M Bhagwat, Pragya Sharma, Bharat Sharma, Pradip P Dalwadi, Ashutosh Sonawane, Alka Subramanyam, Manoj Chadha, Premlata K Varthakavi
Context: Primary hypothyroidism has been thought of as an inflammatory condition characterized by raised levels of cytokines such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α). Depression is also well known to occur in hypothyroidism. Depression is also characterized by elevated inflammatory cytokines. We planned to study whether cytokines play an important part in linking these two conditions. Objectives: (1) To know the prevalence of depression in overt hypothyroidism due to autoimmune thyroid disease...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285453/predisposition-of-angiotensin-converting-enzyme-deletion-deletion-genotype-to-coronary-artery-disease-with-type-2-diabetes-mellitus-in-south-india
#14
Dhivakar Mani, Rathika Chinniah, Padmamalini Ravi, Krishnan Swaminathan, R A Janarthanan, Murali Vijayan, Kamaraj Raju, Balakrishnan Karuppiah
Background: Worldwide, South Asians contribute to a high proportion of coronary artery disease (CAD) burden, mainly attributed to a high prevalence of diabetes. Early identification of such high-risk individuals would enable aggressive disease modification and prevention of complications. Definition of susceptible genotypes early in the course of disease may be one such avenue for reduction in morbidity and mortality from CAD. Aim: Our study was aimed to investigate the insertion/deletion polymorphism of angiotensin-converting enzyme (ACE I/D) gene and susceptibility to CAD in patients with type 2 diabetes mellitus (T2DM) in a South Indian population...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285452/validity-of-madras-diabetes-research-foundation-indian-diabetes-risk-score-for-screening-of-diabetes-mellitus-among-adult-population-of-urban-field-practice-area-indira-gandhi-medical-college-shimla-himachal-pradesh-india
#15
Kanica Kaushal, Anjali Mahajan, Anupam Parashar, Dineshwar Singh Dhadwal, V M S Jaswal, Pramod Jaret, Salig Ram Mazta
Introduction: IDRS is based on four simple parameters derived from known risk factors for diabetes; two modifiable risk factors (waist circumference and physical inactivity) and two non-modifiable risk factors (age and family history of diabetes), which may be amenable to intervention. The present study has been planned as the region specific validation is important before it can be used for screening in this part of the country. Aims: The aim of the present study was to validate MDRF-IDRS for screening of diabetes mellitus among adult population of urban field practice area, IGMC, Shimla, Himachal Pradesh, India...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285451/the-prevalence-of-new-onset-diabetes-mellitus-after-renal-transplantation-in-patients-with-immediate-posttransplant-hyperglycemia-in-a-tertiary-care-centre
#16
Saba Samad Memon, Nikhil Tandon, Sandeep Mahajan, V K Bansal, Asuri Krishna, Arunkumar Subbiah
Objectives: This study aimed to determine the prevalence of immediate posttransplant hyperglycemia and new onset diabetes after renal transplantation (NODAT). It also aims at answering whether posttransplant hyperglycemia per se is a risk factor for future development of NODAT. Methods: A retrospective study was conducted among patients undergoing kidney transplantation under a single surgical unit in a tertiary care hospital in the past 5 years. All known patients with diabetes were excluded from the study...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285450/neutrophil-lymphocyte-ratio-is-a-novel-reliable-predictor-of-nephropathy-retinopathy-and-coronary-artery-disease-in-indians-with-type-2-diabetes
#17
Sachin Chittawar, Deep Dutta, Zahran Qureshi, Vineet Surana, Sagar Khandare, Tribhuvan Nath Dubey
Background and Aims: Neutrophil-lymphocyte ratio (NLR) has been suggested to be a predictor of coronary artery disease (CAD), and end-organ damage in type-2 diabetes mellitus (T2DM). Similar data are lacking from Indians with T2DM. Hence, this study aimed to evaluate the role of NLR as a predictor of microvascular complications and CAD in T2DM. Subjects and Methods: Consecutive T2DM patients attending the outpatient services of 2 different hospitals, who gave consent, underwent clinical, anthropometric evaluation, and evaluation for the occurrence of retinopathy, nephropathy, neuropathy, and CAD...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285449/carotid-intima-medial-thickness-and-glucose-homeostasis-in-indian-obese-children-and-adolescents
#18
Aashima Dabas, Thushanth Thomas, Monita Gahlot, Nandita Gupta, K Devasenathipathy, Rajesh Khadgawat
Objective: To evaluate for subclinical atherosclerosis and its risk factors in Indian obese children. Materials and Methods: A cross-sectional, case-control study was conducted to recruit 80 children aged 6-17 years with constitutional obesity as cases and 23 age- and gender-matched controls with normal body mass index (BMI). Anthropometric and clinical evaluation was followed by biochemical analysis and body fat estimation by dual-energy X-ray absorptiometry in cases...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285448/maternal-and-neonatal-outcome-in-mothers-with-gestational-diabetes-mellitus
#19
G Thiruvikrama Prakash, Ashok Kumar Das, Syed Habeebullah, Vishnu Bhat, Suryanarayana Bettadpura Shamanna
Introduction: Gestational diabetes mellitus (GDM) is common and is accompanied with other comorbidities. Challenges to treatment exist at our institute as it serves women with low income. This study assessed the burden of comorbidities and the outcome of GDM. Methods: This was a prospective, observational study of women with gestational diabetes attending the obstetrics department from September 2012 to April 2014. GDM was diagnosed based on the International Association of Diabetes and Pregnancy Study Groups criteria...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29285447/role-of-parathyroid-hormone-in-determination-of-fat-mass-in-patients-with-vitamin-d-deficiency
#20
Raman K Marwaha, M K Garg, Namita Mahalle, Kuntal Bhadra, Nikhil Tandon
Background: Obesity has become a global epidemic and it is rising is Asia. Vitamin D deficiency (VDD) is widely prevalent in the Indian subcontinent. Studies have linked VDD to obesity and shown correlation between parathyroid hormone (PTH), 25-hydroxy Vitamin D (25(OH)D), and fat mass (FM). However, studies on the role of PTH among subjects with VDD are lacking. Objective: The objective of this study is to study the role of PTH in the determination of FM in participants with VDD...
November 2017: Indian Journal of Endocrinology and Metabolism
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