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International Journal of Clinical Pharmacy

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https://www.readbyqxmd.com/read/28540466/drug-utilization-evaluation-of-albumin-in-a-teaching-hospital-of-mashhad-iran-an-interventional-pre-post-design-study
#1
Farzaneh Zolfagharian, Saba Ghazanfari, Sepideh Elyasi, Paria Iraji, Mohammad Reza Saberi, Nasser Vahdati-Mashhadian, Amir Hooshang Mohammadpour
Background Albumin is a protein colloidal solution with limited availability and high cost. It should be used in such approved indications as paracentesis, extensive burn, spontaneous bacterial peritonitis, and nephrotic syndrome. Objectives The aim of this study was to evaluate and compare the appropriateness of albumin usage before and after an evidence-based guideline. Setting Four wards of Imam Reza Hospital, Mashhad, Iran. Method An interventional pre-post design study was performed on 2 groups of patients; in gGroup 1 as a preparation phase group in 6 months from February 2015 to July 2015 and Group 2 as an interventional group from September 2015 to February 2016...
May 24, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28540465/technology-induced-errors-associated-with-computerized-provider-order-entry-software-for-older-patients
#2
Manuel Vélez-Díaz-Pallarés, Ana María Álvarez Díaz, Teresa Gramage Caro, Noelia Vicente Oliveros, Eva Delgado-Silveira, María Muñoz García, Alfonso José Cruz-Jentoft, Teresa Bermejo-Vicedo
Background The introduction of new technologies in the prescribing process has seen the emergence of new types of medication errors. Objective To determine the prevalence and consequences of technology-induced prescription errors associated with a computerized provider order entry (CPOE) system in hospitalized older patients. Setting Patients 65 years or older admitted to the Departments of Internal Medicine, General Surgery, and Vascular Surgery of a tertiary hospital. Method Prospective observational 6-month study...
May 24, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28523462/statin-prescription-strategies-and-atherogenic-cholesterol-goals-attainment-in-lebanese-coronary-artery-disease-patients
#3
Soubra Lama, Domiati Souraya, Fattouh Youssef
Background Current guidelines recommend a low-density lipoprotein cholesterol goal of <1.8 mmol/L (<70 mg/dL) and a non high-density lipoprotein cholesterol (non-HDL-C) goal of <2.6 mmol/L (<00 mg/dL) for coronary artery disease (CAD) patients. Objective This study aimed to describe real-life statin prescription strategies and to assess their effectiveness in terms of LDL-C and non-HDL-C goals attainment in a cohort of CAD patients. Setting Outpatient cardiology specialty clinics located in main Lebanese cities...
May 18, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28523461/prevalence-and-correlates-of-inappropriate-use-of-benzodiazepines-in-kosovo
#4
Zejdush Tahiri, Suela Kellici, Iris Mone, Driton Shabani, Musa Qazimi, Genc Burazeri
BACKGROUND: In post-war Kosovo, the magnitude of inappropriate use of benzodiazepines is unknown to date. OBJECTIVE: The aim of this study was to assess the prevalence and correlates of continuation of intake of benzodiazepines beyond prescription (referred to as "inappropriate use") in the adult population of Gjilan region in Kosovo. METHOD: A cross-sectional study was conducted in Gjilan region in 2015 including a representative sample of 780 individuals attending different pharmacies and reporting use of benzodiazepines (385 men and 395 women; age range 18-87 years; response rate: 90%)...
May 18, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28523460/evaluation-of-the-effect-of-torsemide-on-warfarin-dosage-requirements
#5
Sophia Lai, Jeremiah D Momper, Felix K Yam
Background According to drug interaction databases, torsemide may potentiate the effects of warfarin. Evidence for this drug-drug interaction, however, is conflicting and the clinical significance is unknown. Objective The aim of this study is to evaluate the impact of torsemide initiation on warfarin dosage requirements. Setting This study was conducted at the Veterans Affairs Healthcare System in San Diego, California. Method A retrospective cohort study was conducted using Veterans Affairs data from patients who were converted from bumetanide to torsemide between March 2014 and July 2014...
May 18, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28508324/impact-of-clinical-pharmacist-intervention-in-anticoagulation-clinic-in-sudan
#6
Nahid Osman Ahmed, Bashier Osman, Yassein Mohamed Abdelhai, Tariq Muhammed Hashim El-Hadiyah
Background Many trials have compared anticoagulation management provided by a pharmacist led anticoagulation clinic versus usual physician care showing the role for clinical pharmacist in the management of anticoagulant therapy, and demonstrating excellent outcomes. In Sudan, there is no published research evaluating the role of pharmacist in providing pharmaceutical care for patients taking warfarin. Objective The objective of the study is to assess the role of clinical pharmacist intervention in warfarin patients compared to usual medical care...
May 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28508323/the-impact-of-pharmacy-monitoring-and-intervention-in-patients-receiving-intravenous-heparin
#7
Michaela C Lysogorski, Amany K Hassan, Stacie J Lampkin, Richard Geisler
Background Intravenous unfractionated heparin (IV UFH) has a narrow therapeutic index and poses a high risk of bleeding. Objective To determine the impact of pharmacy monitoring and intervention on adherence to and appropriate implementation of IV UFH protocol. Setting A 438 bed hospital specializing in cardiac services. Methods This is a retrospective chart review study. Pre-pharmacy intervention data were collected from November 2013 to January 2014 and compared to post-pharmacy intervention data obtained between August 2014 and October 2014...
May 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28508322/use-patterns-of-first-line-inhibitors-of-tyrosine-kinase-and-time-to-change-to-second-line-therapy-in-chronic-myeloid-leukemia
#8
Jorge Enrique Machado-Alba, Manuel Enrique Machado-Duque
Background Chronic myeloid leukemia (CML) has a low incidence but a high burden of disease, and is treated with high-cost tyrosine kinase inhibitors (TKI). Objective To determine the time from the start of a first-line TKI until it passes to second-line, and to establish the reasons for the change of therapy time. Setting Patients with Philadelphia-positive CML treated with some TKI. Methods Retrospective cohort study, between January 1 2007 and July 31 2015, with information obtained from medical records, the time to change initial drugs to secondline therapy, and the reasons for change, were identified...
May 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28500437/an-evaluation-of-the-translation-of-continuing-education-into-diabetes-public-health-care-by-pharmacists
#9
Kerry Wilbur, Sara Shabana, Fatima Maraghi, Alaa ElMubark, Nadir Kheir
Background Pharmacists are assuming greater public health roles and partaking in continuing education to advance knowledge and skills necessary for the provision of this patient care. Objective We sought to determine what conditions in a Middle East context influence how community pharmacists actually incorporate new information into practice. Setting Community pharmacies in Qatar. Methods A continuing professional development (CPD) program regarding the management of fasting diabetes patients during Ramadan was developed and delivered...
May 12, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28500436/the-efficacy-of-a-multimodal-analgesia-protocol-in-preventing-heterotopic-ossification-after-acetabular-fractures-surgery
#10
Liang Cheng, Hai-Tao Long, Bu-Hua Sun, Shu-Shan Zhao, Yong Zhu
Background Heterotopic ossification (HO) after joint surgery is always a disturbing problem for patients and surgeons. Prophylaxis is the most effective therapy. Objective To assess the efficacy and safety of a multimodal analgesia protocol that included parecoxib and celecoxib in preventing HO after acetabular fracture surgery. Setting Selecting patients from trauma registry of our hospital. Method We identified 259 patients who had acetabular fracture surgery between January 2008 and December 2014. Hundredsixty-three patients received parecoxib and celecoxib (Group A) and 96 patients received no prophylaxis (Group B)...
May 12, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28497209/pharmacists-perspectives-of-the-current-status-of-pediatric-asthma-management-in-the-u-s-community-pharmacy-setting
#11
Amanda Elaro, Sinthia Bosnic-Anticevich, Kathleen Kraus, Karen B Farris, Smita Shah, Carol Armour, Minal R Patel
Objective To explore community pharmacists' continuing education, counseling and communication practices, attitudes and barriers in relation to pediatric asthma management. Setting Community pharmacies in Michigan, United States. Methods Between July and September 2015 a convenience sample of community pharmacists was recruited from southeastern Michigan and asked to complete a structured, self-reported questionnaire. The questionnaire elucidated information on 4 general domains relating to pharmacists' pediatric asthma management including: (1) guidelines and continuing education (CE); (2) counseling and medicines; (3) communication and self-management practices; (4) attitudes and barriers to practice...
May 11, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28474305/analgesic-use-by-ageing-and-elderly-patients-with-chronic-non-malignant-pain-a-qualitative-study
#12
Mary-Claire Kennedy, Grainne Cousins, Martin C Henman
Background Analgesics are used in the management of chronic non-malignant pain (CNMP), a condition which is highly prevalent among older adults. CNMP may not only be physically distressing but also complicated by psychosocial and economic factors. An individual's perception and use of analgesics may be influenced by a range of factors such as perceptions of risk or benefits, ability to purchase medication or access to non-pharmacological therapies or specialist care. Objective The aim of this study was to describe the perceptions and experiences of analgesics by ageing and elderly individuals with CNMP and identify factors that influence their use...
May 4, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28466398/factors-associated-with-adverse-drug-reactions-in-older-inpatients-in-teaching-hospital
#13
Tácita Pires de Figueiredo, Ronara Camila de Souza Groia, Soraya Coelho Costa Barroso, Mariana Martins Gonzaga do Nascimento, Adriano Max Moreira Reis
Background Adverse drug reactions (ADRs) occur frequently during hospital stays and are an important public health problem, particularly in the care of the older. Objectives This study aimed to determine the prevalence of ADRs among older inpatients and the factors associated with their occurrence. Setting Brazilian teaching hospital. Methods This was a cross-sectional study with older inpatients in the internal medicine ward of a teaching hospital. The dependent variable was the occurrence of an ADR during hospitalization...
May 2, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28466397/how-does-the-general-public-view-antibiotic-use-in-china-result-from-a-cross-sectional-survey
#14
Dan Ye, Jie Chang, Caijun Yang, Kangkang Yan, Wenjing Ji, Muhammad Majid Aziz, Ali Hassan Gillani, Yu Fang
Background Resistance to antibiotics is a major threat to global health and general public play a significant role in the fight against antimicrobial resistance. Objective The present study aimed to identify the knowledge, attitudes, and practice of the general public towards antibiotic use in China. Setting Randomly selected parks in three cities of western, central and eastern China: Xi'an, Changsha, and Nanjing. Method A cross-sectional survey was conducted on a sample of 1400 residents, from January to June 2015...
May 2, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28466396/utilization-of-simulated-patients-to-assess-diabetes-and-asthma-counseling-practices-among-community-pharmacists-in-qatar
#15
Bridget Paravattil, Nadir Kheir, Adil Yousif
Background Patient counseling is one of the most important services a pharmacist can provide to patients. Studies have shown that counseling provided by pharmacists may prevent medication related problems and improve adherence to medication therapy. Objective To explore counseling practices among community pharmacists using simulated patients and to determine if patient, pharmacist, and pharmacy characteristics influence the counseling provided by community pharmacists. Setting Private community pharmacies within Qatar...
May 2, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28466395/over-the-counter-medications-containing-diphenhydramine-and-doxylamine-used-by-older-adults-to-improve-sleep
#16
Olufunmilola Abraham, Loren Schleiden, Steven M Albert
Background The unintentional misuse of over-the-counter sleep aids among older adults is an important public health problem and a focus of Healthy People 2020. Accordingly, the 2015 Beers Criteria for Potentially Inappropriate Medication Use in Older Adults recommends that individuals 65 years or older avoid use of diphenhydramine and doxylamine; however, many over-the-counter sleep products contain these active ingredients. Objective To identify the proportion of older adults using an over-the-counter medication containing diphenhydramine or doxylamine, and compare their characteristics with older adults using an over-the-counter medication that does not contain these ingredients...
May 2, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28455830/the-iatrogenic-triad-polypharmacy-drug-drug-interactions-and-potentially-inappropriate-medications-in-older-adults
#17
Priscila Horta Novaes, Danielle Teles da Cruz, Alessandra Lamas Granero Lucchetti, Isabel Cristina Gonçalves Leite, Giancarlo Lucchetti
Background The elderly population is often in continuous use of several medications and is more subject to the "iatrogenic triad" of polypharmacy, potentially inappropriate medication use and drug-drug interactions. However, few studies have investigated these three factors concomitantly. Purpose To assess the prevalence and inter-relationship of potentially inappropriate medication (PIM) use, polypharmacy and drug-drug interactions in older adults, together with their associated factors. Setting city of Juiz de Fora, Brazil...
April 28, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28444546/continuous-magnesium-infusions-in-the-management-of-systemic-anti-cancer-therapy-related-hypomagnesaemia
#18
Hector Mateo-Carrasco, Oluwakemi Kostrzynski, Onyinye Ndefo, Simon Stapley, Elaine Davies, Roshan Agarwal
Background Hypomagnesaemia is a relatively-common side effect of some systemic anti-cancer therapies (SACT). Oral and intravenous magnesium (given as injections or short infusions) have problems arising from their poor tolerability, and need for frequent administrations, respectively. Objective Assessing the effectiveness and safety of weekly continuous magnesium infusions (CMI) in the management of SACT-related hypomagnesaemia. Methods CMIs (initiated at 10 mmol/day and up-titrated subject to response) were prescribed to patients with ≥3 magnesium readings <0...
April 25, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28434119/cost-analysis-for-the-implementation-of-a-medication-review-with-follow-up-service-in-spain
#19
Aranzazu Noain, Victoria Garcia-Cardenas, Miguel Angel Gastelurrutia, Amaia Malet-Larrea, Fernando Martinez-Martinez, Daniel Sabater-Hernandez, Shalom I Benrimoj
Background Medication review with follow-up (MRF) is a professional pharmacy service proven to be cost-effective. Its broader implementation is limited, mainly due to the lack of evidence-based implementation programs that include economic and financial analysis. Objective To analyse the costs and estimate the price of providing and implementing MRF. Setting Community pharmacy in Spain. Method Elderly patients using poly-pharmacy received a community pharmacist-led MRF for 6 months. The cost analysis was based on the time-driven activity based costing model and included the provider costs, initial investment costs and maintenance expenses...
April 22, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28417303/paediatric-in-patient-prescribing-errors-in-malaysia-a-cross-sectional-multicentre-study
#20
Teik Beng Khoo, Jing Wen Tan, Hoong Phak Ng, Chong Ming Choo, Intan Nor Chahaya Bt Abdul Shukor, Siao Hean Teh
Background There is a lack of large comprehensive studies in developing countries on paediatric in-patient prescribing errors in different settings. Objectives To determine the characteristics of in-patient prescribing errors among paediatric patients. Setting General paediatric wards, neonatal intensive care units and paediatric intensive care units in government hospitals in Malaysia. Methods This is a cross-sectional multicentre study involving 17 participating hospitals. Drug charts were reviewed in each ward to identify the prescribing errors...
April 17, 2017: International Journal of Clinical Pharmacy
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