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International Journal of Clinical Pharmacy

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https://www.readbyqxmd.com/read/28205064/appropriateness-of-surgical-antibiotic-prophylaxis-for-breast-surgery-procedures
#1
Smeem Jaber, Crystal Rogers, Bruce Sunderland, Richard Parsons, Sarah MacKenzie, Jason Seet, Petra Czarniak
Background Guidelines for the appropriate use of antibiotic prophylaxis are provided in the Therapeutic Guidelines: Antibiotics (eTG) in Australia. Inappropriate use of antibiotics is problematic. Objective To examine adherence with therapeutic guidelines (eTG) in breast surgery and trends in non-adherence dependent on the type of breast surgery performed. Setting Major Western Australian teaching hospital. Method A retrospective cross-sectional study reviewed a random sample of 150 from 1049 eligible medical records of patients who underwent a breast surgical procedure in 2013 or 2014...
February 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28188510/medication-use-and-risk-of-falls-among-nursing-home-residents-a-retrospective-cohort-study
#2
Andrea Bor, Mária Matuz, Márta Csatordai, Gábor Szalai, András Bálint, Ria Benkő, Gyöngyvér Soós, Péter Doró
Background Geriatric falls are leading causes of hospital trauma admissions and injury-related deaths. Medication use is a crucial element among extrinsic risk factors for falls. To reduce fall risk and the prevalence of adverse drug reactions, potentially inappropriate medication (PIM) lists are widely used. Objective Our aim was to investigate the possible predictors of geriatric falls annualized over a 5-year-long period, as well as to evaluate the medication use of nursing home residents. Setting Nursing home residents were recruited from the same institution between 2010 and 2015 in Szeged, Hungary...
February 10, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28188509/anticoagulation-in-atrial-fibrillation-noac-prescribing-in-primary-health-care
#3
Carla Bastida, Núria Corominas, José Miguel Sotoca, Marina Rovira
Background Few studies assess the use of non-vitamin K antagonist oral anticoagulants (NOACs) in daily practice for the prevention of thromboembolic complications associated to nonvalvular atrial fibrillation (AF). Objectives Describe NOACs' use and analyze its prescribing pattern. Evaluate possible factors associated to adverse events (AEs) and the applicability of prescription support forms. Methods We included patients with AF treated with a NOAC during 2014 in three primary healthcare centers in Barcelona, Spain...
February 10, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28188508/potentially-inappropriate-prescribing-and-associated-factors-in-elderly-patients-at-hospital-discharge-in-brazil-a-cross-sectional-study
#4
Ana Luiza Pereira Moreira Mori, Renata Cunha Carvalho, Patricia Melo Aguiar, Maria Goretti Farias de Lima, Magali da Silva Pacheco Nobre Rossi, José Fernando Salvador Carrillo, Egídio Lima Dórea, Sílvia Storpirtis
Background The Screening Tool of Older Persons' Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) criteria is used to identify instances of potentially inappropriate prescribing in a patient's medication regimen. Objective To determine the prevalence and predictors of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) among elderly patients at hospital discharge. Setting A university hospital medical clinic in Brazil. Method Discharge prescriptions were examined using the STOPP/START criteria...
February 10, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28188507/early-recognition-of-coeliac-disease-through-community-pharmacies-a-proof-of-concept-study
#5
LETTER
Heidi Urwin, David Wright, Michael Twigg, Norma McGough
No abstract text is available yet for this article.
February 10, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28160120/erratum-to-a-systematic-review-of-community-pharmacist-therapeutic-knowledge-of-dietary-supplements
#6
Freya Waddington, Mark Naunton, Greg Kyle, Jackson Thomas, Gabrielle Cooper, Ainsley Waddington
No abstract text is available yet for this article.
February 3, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28144804/a-clinical-prediction-model-for-infusion-related-reactions-to-rituximab-in-patients-with-b-cell-lymphomas
#7
Tatsuya Hayama, Katsuhiro Miura, Akihiro Uchiike, Masaru Nakagawa, Daisuke Tsutsumi, Masashi Sakagami, Yoshikazu Yoshida, Masami Takei
Background Infusion-related reactions (IRRs) are a major adverse event of rituximab. Objective To develop a prediction model for IRRs to rituximab among patients with B cell non- Hodgkin's lymphomas (B-NHL). Setting A 1000-bed university hospital in Tokyo. Methods Patients with B-NHL treated with rituximab at our institution from 2004 to 2014 were retrospectively analysed. Chills, fever, rash, nausea, asthenia, headache, cardiovascular symptoms, and respiratory symptoms of any grade, in association with rituximab infusion, were identified as IRRs...
January 31, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28120168/self-care-of-long-term-conditions-patients-perspectives-and-their-limited-use-of-community-pharmacies
#8
Oladapo J Ogunbayo, Ellen I Schafheutle, Christopher Cutts, Peter R Noyce
Background Self-care support is an 'inseparable' component of quality healthcare for long-term conditions (LTCs). Evidence of how patients view and use community pharmacy (CP) to engage in self-care of LTCs is limited. Objective To explore patients' perspectives of engaging in self-care and use of CP for self-care support. Setting England and Scotland. Method Qualitative design employing semi-structured interviews. LTCs patients were recruited via general practitioners (GPs) and CPs. Interviews were conducted between May 2013 and June 2014; they were audio-recorded, transcribed verbatim and analysed thematically...
January 24, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28108846/knowledge-attitudes-practices-and-barriers-related-to-research-utilization-a-survey-among-pharmacists-in-malaysia
#9
Sin Yee Tan, Ernieda Hatah
Background Research utilization is part of evidence-based practice referring to the process of reviewing and critiquing scientific research and applying the findings to one's own clinical practice. Many studies on research utilization have been conducted with doctors and nurses, but to our knowledge, none have been investigated amongst pharmacists. Objective To assess research utilization and its barriers among pharmacists and identify potential influencing factors. Setting Malaysia. Methods This cross-sectional survey was administered online and by mail to a convenient sample of pharmacists working in hospitals, health clinics, and retail pharmacies in rural and urban areas...
January 20, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28120167/thank-you-to-the-reviewers
#10
J W F van Mil
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28093644/guidelines-for-proton-pump-inhibitor-prescriptions-in-paediatric-intensive-care-unit
#11
P Joret-Descout, S Dauger, M Bellaiche, O Bourdon, S Prot-Labarthe
Background Stress ulcer prophylaxis (SUP) is recommended in some situations to prevent upper gastrointestinal bleeding and is a component of standard care for patients admitted to the intensive care unit (ICU). Proton pump inhibitors (PPIs), already among the most widely prescribed drug classes, are being increasingly used. Objective To describe PPI prescribing patterns and their changes after the dissemination of guidelines. Setting Paediatric ICU (PICU), Robert-Debré Teaching Hospital, Paris, France, which admits about 800 patients annually, from full-term neonates to 18-year-olds...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28074393/45th-escp-nsf-international-symposium-on-clinical-pharmacy-clinical-pharmacy-tackling-inequalities-and-access-to-health-care-oslo-norway-5-7-october-2016
#12
(no author information available yet)
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28070689/redispensing-of-medicines-unused-by-patients-a-qualitative-study-among-stakeholders
#13
Charlotte L Bekker, Helga Gardarsdottir, Toine C G Egberts, Marcel L Bouvy, Bart J F van den Bemt
Background Medication waste has undesirable economic and environmental consequences. This waste is partly unavoidable, but might be reduced by redispensing medicines unused by patients. However, there is little knowledge of stakeholders' views on the redispensing. Objective To identify the stakeholders' views on the redispensing of medicines unused by patients. Setting Dutch healthcare system. Method Semi-structured interviews were conducted with 19 Dutch stakeholders from September 2014 until April 2015. The interview guide included two themes: medication waste and redispensing of unused medicines...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28070688/pharmacists-and-patients-feedback-on-empirically-designed-prescription-warning-labels-a-qualitative-study
#14
Olayinka O Shiyanbola, Paul D Smith, Yen-Ming Huang, Sonal Ghura Mansukhani
Background Recommendations call for the inclusion of both patient and provider input in the redesign of prescription labels. Pharmacist opinions on prescription warning labels are important because they are the health providers who would eventually distribute and explain the revised labels during medication counseling. They may be the first health provider to notice a patient's misunderstanding on how to safely use their prescription medications. Objectives To explore the perspectives of patients and pharmacists on five newly designed PWLs, and examine if there were similarities and differences between patients' and pharmacists' perspectives...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28058593/ceftaroline-fosamil-for-community-acquired-pneumonia-and-skin-and-skin-structure-infections-a-systematic-review
#15
Maguy Saffouh El Hajj, Ricky D Turgeon, Kyle John Wilby
Background Ceftaroline is a parentally administered cephalosporin that has an in vitro expanded spectrum of activity compared with other cephalosporins yet data is conflicting regarding its place in therapy. Aim of the Review To compare the efficacy and safety of ceftaroline against standard antibiotic regimens for community-acquired pneumonia (CAP) and complicated skin and skin structure infections (cSSSIs). Method The databases of MEDLINE, EBSCO, and Embase were searched up to June 2016. Manual review of references was completed and experts in the field were contacted for unpublished data...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28050712/optimizing-the-use-of-oral-anticoagulant-therapy-for-atrial-fibrilation-in-primary-care-a-pharmacist-led-intervention
#16
Mandeep S Virdee, Derek Stewart
Background Updated evidence-based guidelines for the management of atrial fibrillation (AF) necessitate patient review, particularly with respect to oral anticoagulants, to ensure maximum health gain around stroke prophylaxis. Objective To quantify the level of anticoagulation utilisation in patients with a CHA2DS2-VASc ≥1/≥2 (male/female) according to evidence-based guidelines and to assess the impact of a pharmacist-led intervention to optimise therapy. Setting Fifteen general medical practices in Liverpool, North-West England with a practice population of 99,129...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28040841/incidence-of-bradycardia-in-pediatric-patients-receiving-dexmedetomidine-anesthesia-a-meta-analysis
#17
Maowei Gong, Yuanyuan Man, Qiang Fu
Background Dexmedetomidine, an α2-receptor agonist, provides potent sedation, analgesia, and anxiolysis without respiratory depression and is used in a variety of surgical and procedural situations. Aim of the review The aim of this study was to estimate the incidence of bradycardia in pediatric patients who received dexmedetomidine as a sole agent for any procedural, intensive care or surgical sedation. Method Literature was searched in electronic databases and studies were selected by following pre-determined eligibility criteria...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28012119/antibiotic-treatment-of-women-with-uncomplicated-cystitis-before-and-after-allowing-pharmacist-supply-of-trimethoprim
#18
Natalie J Gauld, Irene S L Zeng, Rosemary B Ikram, Mark G Thomas, Stephen A Buetow
Background In 2012, New Zealand reclassified trimethoprim to allow specially trained pharmacists to supply it without a prescription to women with symptoms suggesting uncomplicated cystitis, under strict criteria for supply. Objective To assess how this policy change allowing pharmacist supply of trimethoprim affected overall antibiotic supply. Setting Randomly selected community pharmacies throughout New Zealand. Methods Data were collected in pharmacies before the implementation ('baseline') and 1 year later ('post-implementation')...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28012118/risk-factors-for-qtc-prolongation-systematic-review-of-the-evidence
#19
Eline Vandael, Bert Vandenberk, Joris Vandenberghe, Rik Willems, Veerle Foulon
Background QTc-interval prolongation has been associated with serious adverse events, such as Torsade de Pointes and sudden cardiac death. In the prevention of QTc-prolongation, special attention should go to high-risk patients. Aim of the review The aim of this review is to summarize and assess the evidence for different risk factors for QTc-prolongation (demographic factors, comorbidities, electrolytes, QTc-prolonging medication). Methods Potential studies were retrieved based on a systematic search of articles published until June 2015 in the databases Medline and Embase...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28004239/impact-of-team-versus-ward-aligned-clinical-pharmacy-on-unintentional-medication-discrepancies-at-admission
#20
Sharon M Byrne, Tamasine C Grimes, Marie-Claire Jago-Byrne, Mairéad Galvin
Background Medication reconciliation at admission to hospital reduces the prevalence of medication errors. Strategies are needed to ensure timely and efficient delivery of this service. Objective To investigate the effect of aligning clinical pharmacy services with consultant teams, by pharmacists attending post-admission ward rounds, in comparison to a ward-based service, on prevalence of unintentional unresolved discrepancies 48 h into admission. Setting A 243-bed public university teaching hospital in Ireland...
February 2017: International Journal of Clinical Pharmacy
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