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Translational Behavioral Medicine

Mary Kathleen Ladd, Beth N Peshkin, Leigha Senter, Shari Baldinger, Claudine Isaacs, Hannah Segal, Samantha Philip, Chloe Phillips, Kate Shane, Aimee Martin, Veronique Weinstein, Robert Pilarski, Joanne Jeter, Kevin Sweet, Bonnie Hatten, Elisabeth J Wurtmann, Shanda Phippen, Della Bro, Marc D Schwartz
Risk-reducing mastectomy (RRM) and salpingo-oophorectomy (RRSO) are increasingly used to reduce breast and ovarian cancer risk following BRCA1/BRCA2 testing. However, little is known about how genetic counseling influences decisions about these surgeries. Although previous studies have examined intentions prior to counseling, few have examined RRM and RRSO intentions in the critical window between genetic counseling and test result disclosure. Previous research has indicated that intentions at this time point predict subsequent uptake of surgery, suggesting that much decision-making has taken place prior to result disclosure...
November 10, 2018: Translational Behavioral Medicine
Huiying Liu, Vivian W Q Lou
Although ecological momentary assessment (EMA) has been used in youth and adult populations, very few of the studies provided evidence of the feasibility and utility of smartphone-based EMA protocols to collect biopsychosocial data from aging populations. This study aimed to describe the design and implementation of a smartphone-based EMA protocol, and to evaluate the feasibility and utility of this EMA protocol among community-dwelling late-middle-aged and older Chinese. A sample of 78 community-dwelling Chinese aged between 50 and 70 years was trained to participate in a 1-week EMA data collection, during which each participant carried an Android smartphone loaded with a researcher-developed EMA application and a smartphone-based electrocardiogram (ECG) monitor to provide psychosocial (e...
November 5, 2018: Translational Behavioral Medicine
Jennifer L Lee, Ana Gutierrez-Colina, Lillian R Meacham, Ann C Mertens, Jordan Gilleland Marchak
Comprehensive long-term follow-up (LTFU) for survivors of childhood cancer is critical for reducing morbidity and mortality. Current standards recommend screening all survivors for psychological and academic problems and certain survivors for neurocognitive problems based upon treatment exposures. This study aimed to determine if differences exist in executive functioning (EF) based on treatment exposures and characterize relationships between EF, treatment exposure, and internalizing problems. Participants included adolescent and young adult (AYA) survivors (N = 70) of non-central nervous system cancer, aged 14-21 presenting for LTFU...
November 5, 2018: Translational Behavioral Medicine
Allison J Applebaum, Aliza A Panjwani, Kara Buda, Mia S O'Toole, Michael A Hoyt, Adam Garcia, David M Fresco, Douglas S Mennin
Informal caregivers (ICs) are integral to care provided to patients facing life-threatening or incurable illnesses. This responsibility causes considerable burden, as approximately one half of ICs report clinically significant symptoms of depression and/or anxiety that persist when left untreated. Psychosocial interventions containing efficacious treatment principles (e.g., cognitive behavior therapy [CBT]) show disappointing results in reducing anxiety and depression in ICs. This may reflect failure of these interventions to specifically target crucial mechanisms underlying the central feature of distress caused by the patient's illness-notably, perseverative negative thinking (PNT)...
November 5, 2018: Translational Behavioral Medicine
Marjolein E A Verbiest, Callie Corrigan, Sally Dalhousie, Ridvan Firestone, Tevita Funaki, Debbie Goodwin, Jacqui Grey, Akarere Henry, Gayl Humphrey, Andrew Jull, Mereaumate Vano, Crystal Pekepo, Lisa Te Morenga, Robyn Whittaker, Cliona Ni Mhurchu
The obesity rate in New Zealand is one of the highest worldwide (31%), with highest rates among Māori (47%) and Pasifika (67%). Codesign was used to develop a culturally tailored, behavior change mHealth intervention for Māori and Pasifika in New Zealand. The purpose of this article is to provide an overview of the codesign methods and processes and describe how these were used to inform and build a theory-driven approach to the selection of behavioral determinants and change techniques. The codesign approach in this study was based on a partnership between Māori and Pasifika partners and an academic research team...
November 2, 2018: Translational Behavioral Medicine
S Sonia Arteaga, Layla Esposito, Stavroula K Osganian, Charlotte A Pratt, Jill Reedy, Deborah Young-Hyman
Childhood obesity is a major public health challenge. This article describes an overview of the National Institutes of Health (NIH) behavioral and social sciences childhood obesity research efforts. The overview will highlight five areas of childhood obesity research supported by the NIH: (a) basic behavioral and social sciences; (b) early childhood; (c) policies, programs, and environmental strategies; (d) health disparities; and (e) transagency and public-private collaboration. The article also describes potential gaps and opportunities in the areas of childhood obesity and severe obesity, measurement, and sleep...
October 17, 2018: Translational Behavioral Medicine
Courtney Wynne Hess, Justin Karter, Lisa Cosgrove, Laura Hayden
In 2016, the U.S. Preventive Services Task Force recommended routine depression screening for individuals aged 13 and above. Questionnaire-based screening will likely increase treatment in patients with milder symptoms. Although professional groups who develop clinical practice guidelines recognize the importance of considering the risks and benefits of interventions, no official mandate exists for a stepped-care approach. Physical activity warrants increased consideration in guidelines, given the optimal risk/benefit profile and the increasing evidence of efficacy for the treatment and prevention of depression...
October 13, 2018: Translational Behavioral Medicine
Laura C Bouchard, Betina Yanez, Jason R Dahn, Sarah C Flury, Kent T Perry, David C Mohr, Frank J Penedo
Relative to non-Hispanic whites (NHW), black men are disproportionately affected by prostate cancer (PC) incidence, have poorer PC outcomes, and report greater compromises in health-related quality of life. Despite these challenges, black men are underrepresented in psychosocial cancer research, possibly due to limited access to supportive oncology programs. The purpose of this article is to examine the acceptability and efficacy for reducing disease-specific distress of a tablet-delivered psychosocial intervention for older men with advanced PC (APC) and explore differences by race...
October 3, 2018: Translational Behavioral Medicine
Meagan M Graydon, Catherine M Corno, Rebecca L Schacht, Daniel J Knoblach, Alicia E Wiprovnick, Shayla T Thrash, Angela A Petersen, Carlo C DiClemente
Individuals with mental health and substance use disorders smoke at rates two to four times higher than the general population and account for over half of smoking-related deaths. Building capacity of behavioral health providers to provide smoking cessation treatment may decrease smoking prevalence in these groups. The present study evaluated a statewide rollout of a capacity building training program to teach behavioral health providers to deliver a manualized smoking cessation group intervention for patients with mental health and substance use disorders...
September 8, 2018: Translational Behavioral Medicine
Sharon L Manne, Deborah A Kashy, David W Kissane, Melissa Ozga, Shannon Myers Virtue, Carolyn J Heckman
Perceived unsupportive responses from close others play an important role in psychological adaptation of patients with cancer. Little is known about whether these negative responses change after someone experiences a serious life event, and even less is known about the individual characteristics and related factors that might contribute to both the levels of and changes in perceived unsupportive responses over the course of adaptation to an experience. This longitudinal study aimed to evaluate changes in perceived unsupportive behavior from family and friends among women newly with gynecologic cancer as well as initial demographic, disease, and psychological factors that predict the course of perceived unsupportive behavior over time...
September 5, 2018: Translational Behavioral Medicine
Katrina A D'Urzo, Kristiann E Man, Rebecca L Bassett-Gunter, Amy E Latimer-Cheung, Jennifer R Tomasone
"Real-world" initiatives represent an important source of information for evidence-based practice; however, accessing information about initiatives is often challenging. Casebooks are an innovative knowledge translation (KT) tool for researchers, practitioners, and end-users to address "research-to-implementation gaps" through sharing "real-world" experiences. Several casebooks have been published; yet, they remain inconsistent in their methodological approach for identifying "real-world" initiatives...
September 4, 2018: Translational Behavioral Medicine
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No abstract text is available yet for this article.
August 28, 2018: Translational Behavioral Medicine
Jong Y Park, Cecile A Lengacher, Richard R Reich, Carissa B Alinat, Sophia Ramesar, Alice Le, Carly L Paterson, Michelle L Pleasant, Hyun Y Park, John Kiluk, Hyo Han, Roohi Ismail-Khan, Kevin E Kip
Genetic variations of breast cancer survivors (BCS) may contribute to level of residual symptoms, such as depression, stress, fatigue, and cognitive impairment. The objective of this study was to investigate whether particular single-nucleotide polymorphisms (SNPs) moderated symptom improvement resulting from the Mindfulness-Based Stress Reduction for Breast Cancer (MBSR[BC]) program. An overarching goal of personalized medicine is to identify individuals as risk for disease and tailor interventions based on genetic profiles of patients with diseases including cancer...
August 20, 2018: Translational Behavioral Medicine
Lynn P Clemow, Thomas G Pickering, Karina W Davidson, Joseph E Schwartz, Virginia P Williams, Jonathan A Shaffer, Redford B Williams, William Gerin
While behavioral interventions can improve blood pressure (BP) in individuals with hypertension, getting such services to people who could benefit remains difficult. Workplace programs have potential as dissemination vehicles. The objective is to evaluate the effectiveness of a standardized stress management program delivered in groups at the workplace for reducing BP compared with enhanced usual care. This randomized controlled trial studied 92 urban medical center employees with hypertension randomized into two groups...
September 8, 2018: Translational Behavioral Medicine
Simona C Kwon, Shiv Darius Tandon, Nadia Islam, Lindsey Riley, Chau Trinh-Shevrin
There has been increasing recognition of the need to engage patients, families, and other patient stakeholders in research. This article seeks to provide understanding and examples of how to apply core principles of community-based participatory research (CBPR) in developing patient-centered outcomes research (PCOR) that can impact clinical and public health practice. Authors review CBPR principles and demonstrate how to translate them into effective PCOR strategies. Common themes of CBPR principles and PCOR strategies are related to: (a) fostering joint ownership in the identification of health priorities, the development and evaluation of research strategies and their design, and the dissemination of findings; (b) a keen recognition and appreciation for the importance of stakeholder-driven priorities, research, and solutions; (c) building capacity of both stakeholders and researchers to engage in research collaboratively; and (d) recognizing that conducting the research is not the endpoint but continues on with a commitment to dissemination, spread, adoption and sustainability...
September 8, 2018: Translational Behavioral Medicine
Amber Werbrouck, Eva Swinnen, Eric Kerckhofs, Ronald Buyl, David Beckwée, Liesbet De Wit
Patient empowerment, a concept focused on patient-centeredness and patients autonomy, is a well-discussed topic in health literature. However, translating theory into practice is a challenge. The purpose of this study was to assess the effectiveness of interventions on patient empowerment and to identify and compare the modalities of these interventions. For this systematic review including meta-analysis, eligibility criteria were as follows: (i) adult participants with one or more chronic somatic diseases, (ii) "patient empowerment" was explicitly measured (i...
September 8, 2018: Translational Behavioral Medicine
Jun Ma, Megan A Lewis, Joshua M Smyth
In this commentary, we propose a vision for "practice-based translational behavior change research," which we define as clinical and public health practice-embedded research on the implementation, optimization, and fundamental mechanisms of behavioral interventions. This vision intends to be inclusive of important research elements for behavioral intervention development, testing, and implementation. We discuss important research gaps and conceptual and methodological advances in three key areas along the discovery (development) to delivery (implementation) continuum of evidence-based interventions to improve behavior and health that could help achieve our vision of practice-based translational behavior change research...
September 8, 2018: Translational Behavioral Medicine
George A Mensah, Susan M Czajkowski
The prevention and effective treatment of many chronic diseases such as cardiovascular disease, cancer and diabetes are dependent on behaviors such as not smoking, adopting a physically-active lifestyle, eating a healthy diet, and adhering to prescribed medical and behavioral regimens. Yet adoption and maintenance of these behaviors pose major challenges for individuals, their families and communities, as well as clinicians and health care systems. These challenges can best be met through the integration of the biomedical and behavioral sciences that is achieved by the formation of strategic partnerships between researchers and practitioners in these disciplines to address pressing clinical and public health problems...
September 8, 2018: Translational Behavioral Medicine
Whitney C Jones Rhodes, Debra P Ritzwoller, Russell E Glasgow
Cost and other resources required are often primary considerations in whether a potential program or policy will be adopted or implemented and an important element in determining value. However, few economic analyses are conducted from the perspective of patient/family or small-scale stakeholders such as local clinics. We outline and discuss alternative cost assessment and resource expenditures options from the perspective of these small, proximal stakeholders. The perspective of these persons differs from larger societal or health plan perspectives, and often differs across individuals in terms of what they value and the types of expenditures about which they are concerned...
September 8, 2018: Translational Behavioral Medicine
Mary E Cooley, Hermine Poghosyan, Kim Sprunck-Harrild, Jonathan P Winickoff, Stephen B Edge, Karen M Emmons
Cancer survivors are a rapidly growing population and an important target for tobacco treatment interventions. Continued smoking after the diagnosis of cancer is associated with a higher risk of cancer recurrence and mortality. Systematic tobacco cessation programs are effective. This study surveyed American College of Surgeons Commission on Cancer (CoC) programs in the Northeast region of the USA regarding their tobacco control programs. Seventy percent of cancer survivors are treated within CoC programs. The purpose of this study was to describe the extent of implementation of tobacco treatment and determine the organizational delivery of tobacco treatment as measured by the presence of goals to address smoking, leadership support, and integration of tobacco treatment guidelines into care delivery...
September 8, 2018: Translational Behavioral Medicine
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