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International Journal of Ophthalmology

Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
2018: International Journal of Ophthalmology
Hande Taylan Sekeroglu, Kadriye Erkan Turan, Ali Sefik Sanac
No abstract text is available yet for this article.
2018: International Journal of Ophthalmology
Panayiotis Christodoulou, Ioannis Katsimpris
No abstract text is available yet for this article.
2018: International Journal of Ophthalmology
Feng Hu, Yuan Du, Xiao-Yan Peng
No abstract text is available yet for this article.
2018: International Journal of Ophthalmology
Marta Para Prieto, Maria Antonia Saornil, Jesús María de Frutos Baraja, Ciro García Álvarez, Patricia Diezhandino García, Francisco López Lara
The aim of this study is to assess the results of episcleral brachytherapy as treatment of retinal vasoproliferative tumors (RVTs) in a referral Intraocular Tumors Unit (ITU). A retrospective review of all patients diagnosed with vasoproliferative tumors of the retina and treated with episcleral brachytherapy in the ITU, University Hospital of Valladolid between 2009 and 2015 was done. Five patients accomplished the inclusion criteria. All of them presented associated exudation and secondary retinal detachments (RD)...
2018: International Journal of Ophthalmology
Lata Singh, Seema Kashyap
Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor suppressor. Histopathological high-risk features of retinoblastoma are predictive of metastasis or local recurrence. The focus of this update is to emphasize the recent advances in pathology, various molecular key pathways and genome wide approaches for newer potential therapeutic future targets associated with retinoblastoma tumor biology...
2018: International Journal of Ophthalmology
Jie Zhu, Mark Slevin, Bao-Qiang Guo, Shou-Rong Zhu
Corneal blindness caused by limbal stem cell deficiency (LSCD) is one of the most common debilitating eye disorders. Thus far, the most effective treatment for LSCD is corneal transplantation, which is often hindered by the shortage of donors. Pluripotent stem cell technology including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have opened new avenues for treating this disease. iPSCs-derived corneal epithelial cells provide an autologous and unlimited source of cells for the treatment of LSCD...
2018: International Journal of Ophthalmology
Zhi-Chun Zhao, Ying Zhou, Gang Tan, Juan Li
In recent years, people have become increasingly attentive to light pollution influences on their eyes. In the visible spectrum, short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration, even stimulating the brain, inhibiting melatonin secretion, and enhancing adrenocortical hormone production, which will destroy the hormonal balance and directly affect sleep quality...
2018: International Journal of Ophthalmology
Lei Liu, Yan Li, Gui-Sen Zhang, Jing-Yang Wu, Shivani Majithia, Yih-Chung Tham, Han Zhang, Lei Chen
AIM: To identify the most-cited articles in ophthalmic epidemiology over the last decade. METHODS: We performed a cited reference search on articles that were included in the ISI Web of Science database using the terms "Epidemi*" AND "ophthalm*" AND "population*" during year 2006 to 2016. TOP 100 most cited articles (T100) in ophthalmic epidemiology were short listed and analysed using bibliometrics. RESULTS: These top 100 articles in ophthalmic epidemiology were cited between 61 to 333 times...
2018: International Journal of Ophthalmology
De-Sheng Song, Zhi-Jun Chen, Jing Qian
AIM: To compare the effectiveness of unilateral recession-resection (R&R) and bilateral/unilateral recession (BLR/ULR) for treatment of basic type of intermittent exotropia [IX(T)]. METHODS: A comprehensive literature search was performed using PubMed, EMBASE, and the Cochrane Library, to identify randomized controlled trials and comparative studies regarding the effectiveness of R&R and BLR/ULR for IX(T). Based on which, a Meta-analysis was then performed in terms of long-term success rate, overcorrection rate, and recurrence rate...
2018: International Journal of Ophthalmology
Hui Ye, Xiao-Ping Xia
AIM: To investigate the associations between demographic and clinical factors with the rate of visual field mean derivation (MD) decline in retinitis pigmentosa (RP) patients. METHODS: Correlations of MDs with the visual acuity and retinal pigmentation were analyzed in 928 RP patients. MD decreasing rate in 10y and potential influences of gender, age, family history and retinal pigmentation on the rate were explored in 201 RP patients. RESULTS: In the 928 patients, average MD and visual acuity were -14...
2018: International Journal of Ophthalmology
Mohammad Haris Abdianwall, Bahar Güçiz Doğan
AIM: To determine the prevalence, main causes, and related factors of visual impairment (VI) among people aged 50y and over in Jalalabad City and four surrounding districts of Nangarhar Province of Afghanistan. METHODS: The data for the population based cross-sectional study was collected in 2015. The calculated sample size was 1353, allocated to urban-rural strata using probability proportion to size method. At the end of the study, 1281 people participated in to the study...
2018: International Journal of Ophthalmology
Haeng Jin Lee, Jeong-Ah Kim, Seong-Joon Kim, Young Suk Yu
AIM: To evaluate the relation between preoperative hyperopia and surgical outcomes of infantile esotropia in patients younger than 24 months of age. METHODS: Medical records of patients who underwent bilateral medial rectus muscle recession for infantile esotropia between November 1, 2002 and December 1, 2011 were retrospectively reviewed. Patients were divided into two groups according to the degree of preoperative hyperopia. Group I had less than +3.0 diopter (D) of hyperopia and group II had between +3...
2018: International Journal of Ophthalmology
Xiang-Ning Wang, Shu-Ting Li, Wei Li, Yan-Jun Hua, Qiang Wu
AIM: To evaluate the thickness and volume changes of the choroidal, outer retinal layers (ORL) and retinal pigment epithelium (RPE) in patients with diabetic retinopathy (DR) using optical coherence tomography (OCT) and correlate them with visual acuity. METHODS: We carried out a retrospective observational case series. Consecutive DR patients were recruited for color fundus photography and OCT assessment. The RPE, ORL and choroidal thickness were measured. The correlation with the best-corrected visual acuity (BCVA) was also investigated...
2018: International Journal of Ophthalmology
Alberto La Mantia, Alan Hawrami, Heidi Laviers, Sudeshna Patra, Hadi Zambarakji
AIM: To report real-life data on the use of an intravitreal fluocinolone acetonide implant in the treatment of refractory diabetic macular edema (DME) in pars plana vitrectomized (PPV) and non-PPV eyes. METHODS: This was a comparative retrospective observational study of 23 eyes with chronic DME. Best-corrected visual acuity (BCVA) and central macular thickness (CMT) were recorded at baseline, 1, 4 and 12mo. Descriptive statistics and non-parametric tests were performed to analyze and compare PPV and non-PPV eyes...
2018: International Journal of Ophthalmology
Georgios Tsokolas, Hussein Almuhtaseb, Helen Griffiths, Fatima Shawkat, Reuben J Pengelly, Ennis Sarah, Andrew Lotery
AIM: To describe long term follow-up in a family with GUCY2D dominant cone dystrophy. METHODS: Optical coherence tomography scans and fundus autofluorescence images were obtained. Flash and pattern electroretinograms (ERGs) and occipital pattern reversal visual evoked potentials were recorded. RESULTS: Two members of the same family (father and son) were identified to have the heterozygous R838C mutation in the GUCY2D gene. The father presented at the age of 45 with bilateral bull's eye maculopathy and temporal disc pallor...
2018: International Journal of Ophthalmology
Ana Luísa Basílio, Nuno Moura-Coelho, Inês Passos, Mariana Sá Cardoso, Isabel Domingues, Maria Reina, Rita Flores, Teresa Gomes
AIM: To evaluate and compare the quality of life of patients submitted to XEN® implant or trabeculectomy and the relationship with potentially involved variables. METHODS: A cross-sectional study of patients with advanced open-angle glaucoma who underwent implantation of XEN® (group 1) and trabeculectomy (group 2) between October 2015 and February 2017. The studied variables were: age, gender, follow-up time, need of topical anti-hypertensive therapy, visual acuity and intraocular pressure (IOP)...
2018: International Journal of Ophthalmology
Aloisa Librando, Sandra Cinzia Carlesimo, Giorgio Albanese, Giuseppe Maria Albanese, Raffaele Migliorini, Elena Pacella
AIM: To evaluate the efficacy of 0.1% topical salicylic acid (TSA) to treat iatrogenic chronic blepharoconjunctivitis in patients with primary open angle glaucoma (POAG), treated with topical prostaglandin analogues (TPAs). METHODS: Totally 60 patients were randomly distributed into 3 equal size groups, two of which treated with 0.1% TSA (OMKASA® ) and 0.1% topical clobetasone butyrate (TCB; VISUCLOBEN® ) respectively, and one consisting of untreated controls...
2018: International Journal of Ophthalmology
Marcella Nebbioso, Maria Luisa Livani, Valentina Santamaria, Aloisa Librando, Massimiliano Sepe
AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery. METHODS: A prospective and controlled trial including a large cohort of 1650 individuals suffering with bilateral cataract not complicated, in program by phacoemulsification surgery, were randomly assigned to 2 different groups for the type of anesthesia received, 0.4% oxybuprocaine hydrochloride (INN) drops, and INN drops associated to intracameral 1% lidocaine hydrochloride monohydrate...
2018: International Journal of Ophthalmology
Hidenaga Kobashi, Kazutaka Kamiya, Takehiko Sambe, Ryutaro Nakagawa
AIM: To retrospectively investigate the association between dry eye symptoms and clinical or in vivo confocal microscopy parameters in patients with dry eye disease (DED), and to compare these parameters between eyes with DED and normal subjects. METHODS: This retrospective, cross-sectional, controlled study comprised 25 consecutive patients with non-Sjögren dry eye disease and age- and sex-matched 25 healthy subjects. Each patient underwent a complete examination of the ocular surface in the following order: tear osmolarity measurements, InflammaDry test, tear break-up time, corneal fluorescein staining, Schirmer I test, subjective symptoms questionnaire using the dry eye-related quality-of-life score (DEQS), and in vivo confocal microscopy analysis of the central cornea...
2018: International Journal of Ophthalmology
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