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International Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28503446/comment-on-hydration-with-cefuroxime-a-method-for-sealing-a-small-leaking-corneal-perforation
#1
Murat Aslankurt, Osman Çekiç
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503445/optical-coherence-tomography-angiography-in-incomplete-acute-vogt-koyanagi-harada-disease
#2
Gilda Cennamo, Mario R Romano, Claudio Iovino, Giuseppe de Crecchio, Giovanni Cennamo
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503444/keratoconus-associated-with-williams-beuren-syndrome-a-new-case-report
#3
Soraya Mediero, Oriana D'Anna Mardero, Ana Boto de Los Bueis, Susana Noval Martín, Sixto García-Miñaur
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503443/vascular-anomaly-in-the-levator-aponeurosis-of-neurofibromatosis-type-1
#4
Satoru Kase, Toshiya Shinohara, Mika Noda, Susumu Ishida, Manabu Kase
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503442/clinical-outcomes-at-one-year-following-keratoconus-treatment-with-accelerated-transepithelial-cross-linking
#5
Alberto Artola, David P Piñero, Pedro Ruiz-Fortes, Roberto Soto-Negro, Rafael J Pérez-Cambrodí
This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL(®) system, Waltham, MA, USA) over one year of follow-up. The mean depth of the demarcation line measured by optical coherence tomography (OCT) was 205.19 µm. One month after surgery, a non-statistically significant change was noted in sphere (P=0.18) and in spherical equivalent (P=0.17), whereas a significant improvement was observed in corrected distance visual acuity (P=0...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503441/applications-of-crispr-cas9-in-retinal-degenerative-diseases
#6
REVIEW
Ying-Qian Peng, Luo-Sheng Tang, Shigeo Yoshida, Ye-Di Zhou
Gene therapy is a potentially effective treatment for retinal degenerative diseases. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been developed as a new genome-editing tool in ophthalmic studies. Recent advances in researches showed that CRISPR/Cas9 has been applied in generating animal models as well as gene therapy in vivo of retinitis pigmentosa (RP) and leber congenital amaurosis (LCA). It has also been shown as a potential attempt for clinic by combining with other technologies such as adeno-associated virus (AAV) and induced pluripotent stem cells (iPSCs)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503440/mnsod-val16ala-polymorphism-associated-with-retinopathy-risk-in-diabetes-a-prisma-compliant-meta-analysis-of-case-control-studies
#7
Lei Huang, Jun Lyu, Qiu-Ping Liu, Cheng Chen, Tong Wang
AIM: To investigate the association of Manganese superoxide dismutase (MnSOD) Val16Ala polymorphism with diabetic retinopathy (DR). METHODS: PubMed, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to evaluate the strength of the association. Subgroup, sensitivity, and cumulative analyses were performed. Publication bias was also analyzed. RESULTS: Eight studies were included in the pooled analysis...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503439/dry-eye-and-corneal-sensitivity-after-small-incision-lenticule-extraction-and-femtosecond-laser-assisted-in-situ-keratomileusis-a-meta-analysis
#8
Wen-Ting Cai, Qing-Yu Liu, Cheng-Da Ren, Qing-Quan Wei, Jun-Ling Liu, Qian-Yi Wang, Ya-Ru Du, Meng-Mei He, Jing Yu
AIM: To assess the corneal sensitivity and the incidences of dry eye after small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK). METHODS: The Meta-analysis was performed using RevMan 5.3. We searched on PubMed from inception to March 2016. Summary weighted mean difference (WMD) and 95% confidence intervals (CIs) were used to analyze the datum. Random-effects or fixed-effects models were chosen up to between-study heterogeneity...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503438/comparison-of-visual-effects-of-fs-lasik-for-myopia-centered-on-the-coaxially-sighted-corneal-light-reflex-or-the-line-of-sight
#9
Jing Zhang, Shi-Sheng Zhang, Qin Yu, Jing-Cai Lian
AIM: To compare visual quality after femtosecond laser in situ keratomileusis (FS-LASIK), between the coaxially sighted corneal light reflex (CSCLR) group and conventional ablation line of sight (LOS) group. METHODS: In total, 243 eyes (122 patients) were treated with centration on the CSCLR (visual axis) and 238 eyes (119 patients) treated with centration on the pupil center (LOS). Postoperative outcomes [uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA)], safety index, efficacy index, refractive outcome, ablation center distance from the visual axis, corneal high-order aberrations, subjective discomfort glare and shadowing incidence rate, and contrast sensitivity at 1, 3, and 6mo were measured and compared...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503437/comparison-of-postoperative-optical-quality-according-to-the-degree-of-decentering-of-v4c-implantable-collamer-lens
#10
Min Ji Park, Hye Min Jeon, Kyoung Heon Lee, Sang Youp Han
AIM: To evaluate the clinical outcomes of V4c implantable collamer lens (Hole ICL) implantation with regard to the optical quality assessed according to different degrees of decentering. METHODS: This included 49 eyes that received conventional ICL and 94 eyes that received Hole ICL. The eyes that received Hole ICL were divided into three groups according to the degree of decentering: group 1, central hole within 1 hole diameter (HD) from the pupil center; group 2, central hole within 1 HD to 2 HD; and group 3, central hole within 2 HD to 3 HD...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503436/association-of-choroidal-thickness-with-early-stages-of-diabetic-retinopathy-in-type-2-diabetes
#11
Zhi-Jun Shen, Xiu-Fen Yang, Jun Xu, Chong-Yang She, Wen-Wen Wei, Wan-Lu Zhu, Ning-Pu Liu
AIM: To assess the correlation between choroidal thickness (CT) and the early stages of diabetic retinopathy (DR) in type 2 diabetic patients. METHODS: We divided 83 diabetic patients (51-80 years of age; 50 females) into non diabetic retinopathy group (NDR) and mild/moderate nonproliferative diabetic retinopathy (NPDR) group, and compared them with 26 non-diabetic control subjects (51-78 years of age; 16 females). Subfoveal choroidal thickness (SFCT) and parafoveal choroidal thickness (PFCT) were measured using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503435/evaluation-of-hyperreflective-foci-as-a-prognostic-factor-of-visual-outcome-in-retinal-vein-occlusion
#12
Bin Mo, Hai-Ying Zhou, Xuan Jiao, Feng Zhang
AIM: To evaluate the potential role of hyperreflective foci (HF) as a prognostic indicator of visual outcome in patients with macular edema (ME) due to retinal vein occlusion (RVO). METHODS: We retrospectively reviewed 50 eyes of 50 patients with ME due to ischemic central retinal vein occlusion (CRVO), non-ischemic CRVO and branch retinal vein occlusion (BRVO) who were treated with anti-vascular endothelial growth factor (anti-VEGF) at Beijing Tongren Eye Center from January 2013 to July 2016...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503434/comparison-of-isolated-check-visual-evoked-potential-and-standard-automated-perimetry-in-early-glaucoma-and-high-risk-ocular-hypertension
#13
Xiang-Wu Chen, Ying-Xi Zhao
AIM: To compare the diagnostic performance of isolated-check visual evoked potential (icVEP) and standard automated perimetry (SAP), for evaluating the application values of icVEP in the detection of early glaucoma. METHODS: Totally 144 subjects (288 eyes) were enrolled in this study. icVEP testing was performed with the Neucodia visual electrophysiological diagnostic system. A 15% positive-contrast (bright) condition pattern was used in this device to differentiate between glaucoma patients and healthy control subjects...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503433/selective-laser-trabeculoplasty-in-pseudophakic-and-phakic-eyes-a-prospective-study
#14
Myrjam De Keyser, Maya De Belder, Veva De Groot
AIM: To compare the efficacy of selective laser trabeculoplasty (SLT) in replacing medical therapy in pseudophakic and phakic eyes. METHODS: Subgroup of a prospective randomized clinical trial including patients with primary open angle glaucoma or ocular hypertension controlled with medication. Of 38 pseudophakic eyes were matched with 38 phakic eyes. SLT was offered as a way to decrease medication while maintaining the same low eye pressure. SLT was performed over 360°, at 3ns, spotsize 400 µm, 100 spots...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503432/nutrient-patterns-and-risk-of-cataract-a-case-control-study
#15
Fatemeh Sedaghat, Matin Ghanavati, Parisa Nezhad Hajian, Sara Hajishirazi, Mehdi Ehteshami, Bahram Rashidkhani
AIM: To assess the relation between nutrient patterns and cataract risk. METHODS: This is a hospital-based case-control study with 97 cataract patients and 198 matched controls. Dietary consumption was collected through a valid food frequency questionnaire (FFQ). Nutrient patterns were detected by applying factor analysis. Unconditional logistic regression models were used to estimate odds ratio (ORs) and 95%CIs. RESULTS: We extracted 5 main nutrient patterns...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503431/a-pilot-study-of-intraocular-lens-explantation-in-69-eyes-in-chinese-patients
#16
Fang Chai, Bo Ma, Xin-Guang Yang, Juan Li, Mei-Fang Chu
AIM: To study the effects of intraocular lens (IOL) explantation and demographic characteristics. METHODS: Retrospective non-comparative case series. Clinical data recorded from patient charts included the following: demographic, preoperative and postoperative characteristics; complications; surgical methods, and changes in visual acuity. RESULTS: A total of 69 eyes in 67 Chinese patients who received IOL explants were studied. The patients' mean age at the time of explantation was 46...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503430/long-term-rotational-stability-and-visual-outcomes-of-a-single-piece-hydrophilic-acrylic-toric-iol-a-1-5-year-follow-up
#17
Balázs Gyöngyössy, Paul Jirak, Ulrich Schönherr
AIM: To evaluate the rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric intraocular lenses (IOL) over a 1.5-year follow-up period. Data from the 6-month follow-up study have been previously reported. METHODS: Forty eyes of 26 cataract patients (mean age: 72.8±7.9y) with pre-existing corneal astigmatism of 1.0 to 2.6 D were enrolled in the study. Mean axial length was 23.17±0.88 mm. Main outcome measures after implantation of the Torica-aA IOL (HumanOptics) were IOL rotational stability, subjective refraction, astigmatism correction, uncorrected and corrected distance visual acuity (UDVA, CDVA)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503429/suitability-of-open-field-autorefractors-as-pupillometers-and-instrument-design-effects
#18
Carles Otero, Mikel Aldaba, Oriol Ferrer, Andrea Gascón, Juan C Ondategui-Parra, Jaume Pujol
AIM: To determine the agreement and repeatability of the pupil measurement obtained with VIP-200 (Neuroptics), PowerRef II (Plusoptix), WAM-5500 (Grand Seiko) and study the effects of instrument design on pupillometry. METHODS: Forty patients were measured twice in low, mid and high mesopic. Repeatability was analyzed with the within-subject standard deviation (Sw) and paired t-tests. Agreement was studied with Bland-Altman plots and repeated measures ANOVA. Instrument design analysis consisted on measuring pupil size with PowerRef II simulating monocular and binocular conditions as well as with proximity cues and without proximity cues...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503428/soluble-expression-of-recomb-inant-cmyc-klf4-oct4-and-sox2-proteins-in-bacteria-and-transduction-into-living-cells
#19
Guo-Dan Liu, Shi-Feng Zhou, Xu-Chen Ding, Chun-Lai Fang, Shu-Yong Mi, Xiang-Chun Gao, Qing Han
AIM: To develop a new method to produce recombinant reprogramming proteins, cMyc, Klf4, Oct4, and Sox2, in soluble format with low cost for the generation of induced pluripotent stem cells (iPSCs). METHODS: A short polypeptide sequence derived from the HIV trans-activator of transcription protein (TAT) and the nucleus localization signal (NLS) polypeptide were fused to the N terminus of the reprogramming proteins and they were constructed into pCold-SUMO vector which can extremely improve the solubility of recombinant proteins...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503427/expressions-of-matrix-metalloproteinases-1-and-3-and-their-tissue-inhibitors-in-the-conjunctival-tissue-and-fibroblasts-cultured-from-conjunctivochalasis
#20
Min-Hong Xiang, Xing-Ru Zhang, Zhen-Yong Zhang, Qing-Song Li, Han-Min Wang, Zhu-Mei Han, Huan-Ming Zhou, Yuan-Ling Jia, Xing-Xing Chen
AIM: To investigate the expression of matrix metalloproteinases 1 and 3 (MMP-1 and MMP-3) and their tissue inhibitors of metalloproteinases 1 and 3 (TIMP-1 and TIMP-3) in the conjunctiva of eyes with conjunctivochalasis (CCh). METHODS: The conjunctival tissue was obtained from the CCh patients and controls, the MMPs/TIMPs expression concentration was determined by enzyme-linked immuno-sorbent assay (ELISA) and immunofluorescence staining. The expression levels of MMPs/TIMPs in the CCh fibro-blasts were determined by analyzing its concentration in the cellular supernatant that was abstracted from the in vitro cultured CCh fibroblasts...
2017: International Journal of Ophthalmology
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