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Journal of Ophthalmic Inflammation and Infection

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https://www.readbyqxmd.com/read/30076485/necrotising-retinopathy-like-lesions-as-a-manifestation-of-ocular-sarcoidosis
#1
Florence Rasquin, Nacima Kisma, Laure Van Bol
BACKGROUND: A 56-year-old Caucasian man presented with a 2-weeks history of decreased vision in the right eye. Vitritis, papillitis, cystoid macular oedema and inferior diffuse retinal infiltration were noticed. Extensive blood work-up, anterior chamber paracentesis with polymerase chain reaction (PCR) and Goldmann-Witmer coefficient, tuberculin skin test (PPD-test), fluorodeoxyglucose Positron Emission Tomography CT scan (FDG-PET/CT), lymph node biopsy and pars plana vitrectomy were performed...
August 3, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29971681/specialty-management-differences-of-syphilis-and-toxoplasmosis-surrounding-pregnancy-a-prospective-cross-sectional-study
#2
Jared S Fredrickson, Jennifer Holmes, Jennifer N Cathcart, Anne M Lynch, Jason R Kolfenbach, Alan G Palestine
BACKGROUND: Syphilis and toxoplasmosis are two infectious conditions that can occur during pregnancy. Both these diseases can have ocular manifestations and thus are treated by ophthalmologists and obstetricians. We hypothesized that specialty training would affect the way physicians selected therapy. RESULTS: A total of 209 uveitis specialists and approximately 2500 obstetricians across the USA were surveyed using an online questionnaire distributed via listserv and social media posts...
July 3, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29915970/comparison-of-surgical-outcomes-of-trabeculectomy-ahmed-shunt-and-baerveldt-shunt-in-uveitic-glaucoma
#3
Audrey Chow, Bruce Burkemper, Rohit Varma, Damien C Rodger, Narsing Rao, Grace M Richter
BACKGROUND: Uveitis is defined as a collection of syndromes involving intraocular inflammation which can lead to pain, tissue damage, and vision loss. Ophthalmic surgery in uveitis patients can be challenging due to inflammation-induced fibrosis and scarring. Trabeculectomy and implantation of glaucoma drainage devices (aqueous shunts) have been used in surgical management of uveitic glaucoma, however there is a paucity of literature examining the comparative results of these entities in this unique setting...
June 18, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29904801/toxoplasma-gondii-bradyzoites-and-tachyzoites-isolation-from-vitreous-of-atypical-necrotizing-retinitis
#4
Ranju Kharel Sitaula, Sagun Narayan Joshi, Ranjit Sah, Sushila Khadka, Anadi Khatri Kc, Bharat Mani Pokharel
BACKGROUND: Detection of Toxoplasma gondii cysts in vitreous of immunocompetent patient with necrotizing retinitis is extremely rare. We herein report the isolation of Toxoplasma bradyzoites and tachyzoites from the vitreous of healthy person. RESULTS: A 19-year-old immunocompetent female presented with sudden loss of vision in left eye since 1 week. The BCVA was 6/6 and HM in right and left eye. The left eye finding was suggestive of diffuse necrotizing retinitis with retinal detachment...
June 15, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29671151/an-atypical-case-of-neurosarcoidosis-presenting-with-neovascular-glaucoma
#5
REVIEW
Melissa Vereecken, Karolien Hollanders, Deborah De Bruyn, Virginie Ninclaus, Julie De Zaeytijd, Ilse De Schryver
BACKGROUND: Sarcoidosis, a multisystem, granulomatous disorder, sometimes manifests with a neuro-ophthalmic subtype. The latter can pose a diagnostic challenge, especially when ocular symptoms appear before systemic involvement, as the clinical picture then can be non-specific and systemic laboratory and standard imaging investigations can be negative. FINDINGS: A 71-year-old woman presented with a 4-month history of sudden-onset visual loss in the left eye. Slit lamp examination revealed anterior chamber cells, iris, and angle neovascularization...
April 18, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29666980/epidemiology-of-uveitis-in-a-us-population-based-study
#6
Marta Mora González, Marissé Masís Solano, Travis C Porco, Catherine E Oldenburg, Nisha R Acharya, Shan C Lin, Matilda F Chan
BACKGROUND: The purpose of this study is to assess the relationship between self-reported uveitis and purported demographic and clinical risk factors, using an American adult population extracted from the National Health and Nutrition Examination Survey (NHANES) for the years 2009 and 2010. This is a cross-sectional, population-based study using a sample of 5106 subjects between 20 and 69 years old. The main outcome for our study was the self-report of a diagnosis of uveitis. The demographic analysis included age, gender, and ethnicity...
April 17, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29589220/ocular-involvement-in-melioidosis-a-23-year-retrospective-review
#7
Sasi Yaisawang, Somkiat Asawaphureekorn, Ploenchan Chetchotisakd, Surasakdi Wongratanacheewin, Peerapat Pakdee
BACKGROUND: Ocular involvement in melioidosis is rare and has devastating outcomes. Although there have been few reports on the condition, Khon Kaen, a city in northeast Thailand, has been called the "capital of melioidosis" due to the high prevalence of the condition in the region. We retrospectively reviewed all admitted cases of melioidosis with ocular involvement from the two largest hospitals in Khon Kaen. We reviewed cases from Srinagarind Hospital (a university hospital) of patients admitted between 1993 and 2016 and from Khon Kaen Hospital (a provincial hospital) of patients who presented from 2012 to 2016...
March 27, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29516199/keratoconus-like-tomographic-changes-in-a-case-of-recurrent-interstitial-keratitis
#8
Marie-Sophie Hanet, Annette Zimpfer, Sabine Lepper, Berthold Seitz
BACKGROUND: The purpose of this report was to describe a single case of recurrent interstitial keratitis in a young patient leading to keratoconus-like corneal changes. RESULTS: Over the 2 years follow-up, the patient developed clinical signs of keratoconus with Vogt's striae, Fleischer Ring and paracentral stromal thinning in the affected eye only. The tomographic measurements revealed a rapid reduction of corneal thickness from 581 to 303 μm and an irregular steepening of the pathological cornea...
March 7, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29356903/tubercular-retinal-vasculitis-mimicking-frosted-branch-angiitis-a-case-report
#9
Manisha Agarwal, Ankita Shrivastav, Abdul Waris
BACKGROUND: Tubercular vasculitis is an important manifestation of ocular tuberculosis and this report highlights the mimicking nature of the disease with frosted branch angiitis. RESULTS: A patient presented with a severe form of retinal vasculitis in both eyes and a branch retinal vein occlusion in the left eye. He had a positive tuberculin skin test (TST) and a raised erythrocyte sedimentation rate (ESR) and serum angiotensin-converting enzyme (ACE) levels. Radiological investigations revealed a sub-pleural nodule and mediastinal lymph nodes, which on histopathological evaluation confirmed a granulomatous etiology...
January 22, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29322275/outcome-of-polymerase-chain-reaction-pcr-analysis-in-100-suspected-cases-of-infectious-uveitis
#10
Ranju Kharel Sitaula, M K Janani, H N Madhavan, Jyotirmay Biswas
BACKGROUND: Polymerase chain reaction (PCR) analysis is an important tool in the diagnosis of infectious uveitis. A retrospective, interventional study of PCR analysis of ocular fluid in suspected infectious uveitis cases between January 2014 to July 2016 was done. Nested, real-time and broad range PCR was performed for detection of the genome of Mycobacterium tuberculosis, herpes virus family, Chikungunya virus, Toxoplasma gondii, fungus, eubacterium and propionibacterium acne. RESULTS: Total of 100 cases included, mean age was 39...
January 10, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29313162/correction-to-the-role-of-oral-co-trimoxazole-in-treating-nocardia-farcinica-keratitis-a-case-report
#11
Neharika Sharma, Stephen O'Hagan
This article [1] was unintentionally published twice in this journal, by the same authors.The following [1] should be considered the version of record and used for citation purposes: "Neharika Sharma and Stephen O'Hagan, The role of oral co-trimoxazole in treating Nocardia farcinica keratitis: a case report. Journal of Ophthalmic Inflammation and Infection (2016) 6:21 DOI 10.1186/s12348-016-0087-y".The duplicate [2]: "Neharika Sharma and Stephen O'Hagan, The role of oral co-trimoxazole in treating Nocardia farcinica keratitis: a case report...
January 8, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29247280/rothia-dentocariosa-endophthalmitis-following-intravitreal-injection-a-case-report
#12
LETTER
R A Hayes, H Y Bennett, S O'Hagan
PURPOSE: This report describes the first recognised case of Rothia dentocariosa endophthalmitis following intravitreal injection. CASE REPORT: A 57-year-old indigenous Australian diabetic female developed pain, redness and decreased vision 3 days after intravitreal aflibercept injection to the right eye-administered for diabetic vitreous haemorrhage with suspected macular oedema and proliferative diabetic retinopathy. Examination revealed best corrected visual acuity (BCVA) of hand movements, ocular hypertension and marked anterior chamber inflammation...
December 16, 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29204932/a-retrospective-cohort-study-of-patients-treated-with-anti-tuberculous-therapy-for-presumed-ocular-tuberculosis
#13
Erika Marie Damato, Sarah Dawson, Xiaoxuan Liu, Chandoshi Mukherjee, John Horsburgh, Alastair K Denniston, Edward Moran, Martin Dedicoat, Philip Ian Murray
BACKGROUND: Uveitis involving the posterior segment is a significant and potentially blinding condition. The diagnosis and treatment of patients with uveitis associated with tuberculosis remains controversial, and commonly, patients are systemically well. Use of the interferon-gamma release assays has added to the controversy, as the significance of a positive test may be uncertain. We aim to report the outcomes of anti-tuberculous treatment in a cohort of patients treated in Birmingham, for presumed "ocular tuberculosis", based on clinical findings, systemic assessment and specific testing for tuberculosis...
December 4, 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28744830/dabrafenib-for-cutaneous-melanoma-infiltrating-the-vitreous-regression-of-metastasis-and-occurrence-of-uveitis-as-a-secondary-effect
#14
LETTER
Alex Fonollosa, Jose Gabriel Vargas-Kelsh, Gonzaga Garay-Aramburu, Angel Saiz, Ignacio Zabalza-Estevez, Ricardo Fernandez
Intraocular metastasis of cutaneous melanoma is extremely infrequent. This typically occurs in advanced metastatic disease and has a poor survival prognosis. The most frequent reported treatment is radiotherapy. BRAF inhibitors are new, orally administered and very effective drugs used for metastatic cutaneous melanoma. Herein, we report a case of a 58-year-old patient with a recent diagnosis of cutaneous melanoma who consulted for floaters and presented vitreous opacities in both eyes. A diagnostic vitrectomy of his left eye was performed and pathologic analysis disclosed infiltrating melanoma cells in the vitreous...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28695542/wide-field-fluorescein-and-indocyanine-green-angiography-findings-in-the-eyes-with-vogt-koyanagi-harada-disease
#15
Ryo Kurobe, Yoshio Hirano, Naomi Niwa, Kazuhiko Sugitani, Tsutomu Yasukawa, Munenori Yoshida, Yuichiro Ogura
BACKGROUND: The purpose of this study is to report wide-field angiography findings before and after steroid therapy in a case with bilateral Vogt-Koyanagi-Harada (VKH) disease. RESULTS: A 44-year-old woman presented with bilateral blurred vision and metamorphopsia accompanied by symptoms of headache and tinnitus. The baseline best-corrected visual acuity was 20/20 in both eyes. Ophthalmic examination revealed a shallow anterior chamber and panuveitis accompanied by multiple serous retinal detachments in both eyes and ciliochoroidal detachments in the left eye...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28608297/neomycin-polymyxin-b-and-dexamethasone-allergic-reactions-following-periocular-surgery
#16
Nicholas A Moore, Craig N Czyz, Tracy D Carter, Jill A Foster, Kenneth V Cahill
BACKGROUND: The aim of this study was to evaluate the rate of periocular allergic skin reactions to topical neomycin, polymyxin B, and dexamethasone (NPD) ophthalmic ointment. METHODS: A consecutive patient prospective study was performed. A total of 522 patients who had a procedure involving incision of the periocular skin with subsequent postoperative application of NPD ophthalmic ointment were included. Patients were evaluated for signs of allergy at 1 week postoperatively or prior if the patient had complaints...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28560576/dengue-associated-choroiditis-a-rare-entity
#17
Harshali Manish Yadav, Parthopratim Dutta Majumder, Jyotirmay Biswas
BACKGROUND: We report a case of choroiditis during dengue fever. RESULTS: A 35-year-old female presented with blurring of vision during dengue fever. Her fundus examination revealed yellow deep choroidal lesions at right macula, multiple small, yellowish subretinal macular dots along papillomacular bundle, and hyperemic disc. There was a small retinal hemorrhage at temporal margin of disc. The left eye had similar small discrete lesion superonasal and inferotemporal to macula...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28536985/anterior-segment-optical-coherence-tomography-and-retained-vegetal-intraocular-foreign-body-masquerading-as-chronic-anterior-uveitis
#18
Anis Mahmoud, Riadh Messaoud, Fatma Abid, Imen Ksiaa, Melek Bouzayene, Moncef Khairallah
BACKGROUND: The purpose of this single case report was to report the use of anterior segment optical coherence tomography for the diagnosis and management of a retained vegetal intraocular foreign body. RESULTS: A 23-year-old otherwise healthy male presented with a progressive vision loss in the right eye (RE). He reported a mild ocular trauma with a tree leaf 1 year ago followed by recurrent episodes of redness and pain in the RE that partially resolved after a self-medication with topical steroids...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28534271/optic-disc-granuloma-with-epididymitis-a-diagnostic-challenge
#19
Parthopratim Dutta Majumder, Sowkath Ali, Jyotirmay Biswas
BACKGROUND: Sarcoidosis and tuberculosis (TB) share epidemiological, immunological, and molecular features common to both, and often, it becomes difficult to differentiate them especially in a highly TB-endemic country like India. We report a case of optic disc granuloma along with epididymitis and infertility in a male who showed a response to treatment with anti-tuberculosis therapy and steroids. RESULTS: A 35-year-old Indian male who presented with complaints of blurring vision in the right eye for 6 months and treated elsewhere with two intravitreal injections of anti-VEGF was found to have optic disc granuloma in the right eye...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28421562/prevention-of-bacterial-biofilm-formation-on-soft-contact-lenses-using-natural-compounds
#20
Amira M El-Ganiny, Ghada H Shaker, Abeer A Aboelazm, Heba A El-Dash
PURPOSE: In eye care field, contact lenses (CL) have a great impact on improving vision, but their use can be limited by ocular infection. CL- associated infections can be reduced by good attention to CL storage case practice. CL-care solutions should be able to control microbial growth on CL. The aim of the study was to evaluate and compare the efficacy of CL-care solutions (found in Egyptian market) with some natural compounds in removal and inhibition of bacterial biofilm formed on soft CL...
December 2017: Journal of Ophthalmic Inflammation and Infection
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