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Journal of Ophthalmic Inflammation and Infection

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https://www.readbyqxmd.com/read/27896784/ocular-involvement-associated-with-varicella-in-adults
#1
Salma Gargouri, Sana Khochtali, Sourour Zina, Molka Khairallah, Imen Zone-Abid, Imen Kaibi, Salim Ben Yahia, Jamel Feki, Moncef Khairallah
BACKGROUND: Varicella is a common infectious disease primarily of childhood that is usually benign and self-limited. It is, however, increasingly seen in adults who are at a higher risk of severe infection. Ocular complications of varicella are relatively uncommon and have been rarely described in adults. We describe herein five adults who developed ocular involvement in association with primary varicella-zoster virus infection. FINDINGS: Ocular manifestations included acute anterior uveitis in four eyes, with associated stromal keratitis in one of them, epithelial ulcerative keratitis in the two eyes of one patient, and acute retinal necrosis in one eye...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27896783/post-clear-corneal-phacoemulsification-endophthalmitis-profile-and-management-outcomes-at-a-tertiary-eye-care-center-in-western-india
#2
Aditya S Kelkar, Jai A Kelkar, Prajakta M Barve, Aishwarya Mulay, Shubhangi Sharma, Winfried Amoaku
BACKGROUND: Infectious endophthalmitis is a serious sight threatening intraocular inflammation that results from exogenous or endogenous spread of organisms into the eye.A retrospective case series to study the profile of endophthalmitis following clear corneal phacoemulsification in western India between years 2008 and 2014 was held in the National Institute of Ophthalmology, Pune, India. Cases of endophthalmitis post-clear corneal phacoemulsification were reviewed pertaining to demography, clinical history, surgeon experience, surgical complications, time of onset following surgery, duration between onset of symptoms and presentation to the center, presenting visual acuity and at follow-ups, slit-lamp examination and ultrasound findings, vitreous tap culture results, treatment, and final functional and anatomical outcomes...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27888495/an-unusual-presentation-of-intraocular-tuberculosis-in-a-monocular-patient-clinicopathological-correlation
#3
Kanika Aggarwal, Aniruddha Agarwal, Shobha Sehgal, Suryaprakash Sharma, Nirbhai Singh, Kusum Sharma, Ramanuj Samanta, Alessandro Invernizzi, Aman Sharma, Vishali Gupta
BACKGROUND: Lack of uniform diagnostic criteria often poses a challenge in the diagnosis and management of tubercular uveitis. The index case describes an unusual presentation of tubercular panuveitis initially misdiagnosed as sympathetic ophthalmia, where the appropriate diagnosis was made using various imaging and laboratory investigations. RESULTS: A 52-year-old Indian woman underwent multimodal imaging, extensive clinical and laboratory work-up, and analysis of microbiological and histopathological specimens...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27882513/comparison-of-clinico-microbiological-profile-and-treatment-outcome-of-in-house-and-referred-post-cataract-surgery-endophthalmitis-in-a-tertiary-care-center-in-south-india
#4
Vikas Ambiya, Taraprasad Das, Savitri Sharma, Jay Chhablani, Vivek Dave, Subhadra Jalali, Raja Narayanan, Joveeta Joseph
BACKGROUND: The purpose of the study is to compare the clinico-microbiological profile and treatment outcome of in-house vs referred cases of post cataract surgery endophthalmitis in a tertiary eye care facility in South India. METHODS: The clinical records of 50 culture-positive cases each of in-house (group A) and referred (group B) post cataract surgery endophthalmitis were analyzed. The management protocol was similar in both groups. RESULTS: The time to report to the institute was longer in group B (group B 13...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27864795/prevalence-of-ocular-surface-disease-symptoms-and-risk-factors-in-group-of-university-students-in-monterrey-mexico
#5
Manuel Garza-León, Miguel Valencia-Garza, Bernardo Martínez-Leal, Pablo Villarreal-Peña, Hernán Gerardo Marcos-Abdala, Ana Lucía Cortéz-Guajardo, Arturo Jasso-Banda
BACKGROUND: The objective of this study was to determine the prevalence of symptoms of ocular surface disease and its relationship with associated risk factors in students from the University of Monterrey using Ocular Surface Disease (OSDI) questionnaire. METHODS: A cross-sectional survey was conducted between October and December 2014 to assess the prevalence and risk factors for ocular surface disease in a group of students from Universidad de Monterrey in Monterrey, Mexico...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27822745/dematiaceous-fungal-endophthalmitis-report-of-a-case-and-review-of-the-literature
#6
LETTER
Austin R Fox, Kourtney H Houser, William R Morris, R Christopher Walton
BACKGROUND: Pleurostomophora richardsiae (formerly Phialophora richardsiae) is a dematiaceous fungus that is an uncommon cause of ocular infection. Herein, we present a case of endogenous endophthalmitis associated with disseminated P. richardsiae infection. FINDINGS: This is a descriptive case report with a brief review of literature. A 43-year-old male admitted to the hospital following an acute cerebellar hemorrhage was found to have a swollen and tender wrist...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27822744/bevacizumab-for-paradoxical-worsening-treatment-adjunct-in-hiv-patient-with-choroidal-tuberculoma
#7
LETTER
Sahil Jain, Priya Bajgai, Basavaraj Tigari, Kusum Sharma, Aman Sharma, Vishali Gupta, Ramandeep Singh
The use of anti-tubercular therapy (ATT) along with anti-retroviral therapy (ART) in human immunodeficiency virus-tuberculosis (HIV-TB) co-infected individuals could at times lead to paradoxical worsening due to an increase in the inflammatory activity due to immune reconstitution inflammatory syndrome (IRIS) in the eye. This is characterized by anterior and posterior segment inflammatory reactions which may occur in the form of serous retinal detachment. We describe a case where the use of intravitreal anti-vascular endothelial growth factor (anti-VEGF) agent led to resolution of the serous retinal detachment, which had failed to respond to other common modalities of treatment...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27822743/immune-recovery-uveitis-in-hiv-patients-with-cytomegalovirus-retinitis-in-the-era-of-haart-therapy-a-5-year-study-from-singapore
#8
Tun Hang Yeo, Tun Kuan Yeo, Elizabeth P Wong, Rupesh Agrawal, Stephen C Teoh
BACKGROUND: The aim of this study is to analyse the clinical features of HIV patients with cytomegalovirus retinitis (CMVR) developing immune recovery uveitis (IRU) while on highly active antiretroviral therapy (HAART) and to identify the risk factors, visual outcomes and complications of IRU. RESULTS: Majority (n = 26, 86.7 %) of patients were male, with 76.7 % (n = 23) of patients having bilateral disease. Twenty-seven eyes (50.9 %) had both anterior uveitis and vitritis...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27785746/bilateral-multiple-choroidal-granulomas-and-systemic-vasculitis-as-presenting-features-of-tuberculosis-in-an-immunocompetent-patient
#9
Nitin Kumar, Sridharan Sudharshan, Sudha K Ganesh, Gopal Lingam, Jyotirmay Biswas
BACKGROUND: Multiple choroidal granulomas are a rare presentation of tuberculosis. Choroidal granulomas in immunocompetent patients can pose difficulty in diagnosis as in most cases systemic examination may not reveal any evidence of tuberculosis. We report a case of bilateral multiple choroidal granulomas with systemic vasculitis-like features and disseminated tuberculosis in an immunocompetent patient without pulmonary involvement. FINDINGS: A 26-year-old male Indian patient presented with bilateral blurred vision and systemic illness with vasculitis-like features...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27771870/disseminated-nontuberculous-mycobacterial-infection-with-multifocal-retinitis-and-vasculitis-in-an-immunocompromised-patient-with-anti-ifn-%C3%A9-autoantibodies
#10
Tian Loon Lee, Rupesh Agrawal, Jackie Yu-Ling Tan, Kiat Hoe Ong, Chen Seong Wong, Su Ling Ho
BACKGROUND: Nontuberculous mycobacteria (NTM) are found ubiquitously in the environment. Since exposure to NTM is universal, infection likely represents underlying host susceptibility factors. Anti-IFN-ɣ autoantibodies have been described previously in patients with NTM. Up to 88 % of patients with disseminated NTM or other opportunistic infections have high-titer anti-IFN-ɣ autoantibodies, compared with 2 % of patients with TB and healthy controls. FINDINGS: We report a unique presentation of a patient with anti-IFN-ɣ autoantibodies with disseminated NTM infection who presents with panuveitis with multifocal retinitis and vasculitis...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27757929/a-national-survey-of-canadian-ophthalmologists-to-determine-awareness-of-published-guidelines-for-the-management-of-uveitis
#11
Crystal S Y Cheung, Nima Noordeh, Chloe C Gottlieb
BACKGROUND: The objectives of this study are to assess Canadian ophthalmologists' awareness of established uveitis treatment guidelines and clinical management of uveitis and to assess the frequency of government applications for immunomodulatory therapy (IMT) and identify primary prescribers. A 25-item questionnaire was sent to 759 practicing Canadian ophthalmologists. Six questions assessed demographics including the year of residency completion, training by uveitis specialists during residency, and fellowship training...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27734292/refractory-necrotizing-scleritis-successfully-treated-with-adalimumab
#12
Lola E Lawuyi, Avinash Gurbaxani
Necrotizing scleritis is the most severe and destructive form of scleritis with vision-threatening sequelae. It is divided into with inflammation and without inflammation (scleromalacia perforans). Adalimumab is a tumour necrosis factor (TNF)-inhibiting anti-inflammatory medication licensed for the treatment of rheumatoid and psoriatic arthritis, ankylosing spondylitis and inflammatory bowel disease (in the USA). We report two cases of necrotizing scleritis successfully treated with adalimumab.
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27714662/personality-and-uveitis
#13
Ankush Kawali, Ringhoo Theresa Jose, Aishwarya, Mathew Kurian, Kushal Kacha, Padmamalini Mahendradas, Rohit Shetty
BACKGROUND: Psycho-immunology is an emerging branch of science which studies the interaction between the brain and the immune system. The purpose of this study is to identify the types of personality factors in patients with non-infectious uveitis and to find its association with a particular uveitic entity if any. This is a prospective, observational, case-control study of 186 patients with non-infectious uveitis (group A) and controls from general ophthalmology outpatient department (group B)...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27687961/assessment-of-vitreous-haze-using-ultra-wide-field-retinal-imaging
#14
Drew Dickson, Aniruddha Agarwal, Mohammad Ali Sadiq, Muhammad Hassan, Robin High, Quan Dong Nguyen, Yasir J Sepah
BACKGROUND: Conventional fundus imaging has been used to assess vitreous haze (VH) in patients with uveitis. Ultra-wide field (UWF) retinal imaging that uses scanning laser technology has not been evaluated for the detection of VH. This pilot study evaluates the ability of UWF imaging in detecting VH. Patients with intermediate, posterior, or panuveitis were examined to assess the level of VH using slit-lamp biomicroscopy. Colored fundus images were acquired using a Carl Zeiss FF450 camera...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27638462/a-rare-case-of-atypical-sympathetic-ophthalmia-post-therapeutic-keratoplasty
#15
LETTER
Vipul Bhandari, Sri Ganesh ᅟ, Mohan Raj, Akanksha Batra
INTRODUCTION: Sympathetic ophthalmia (SO) is a rare, bilateral, diffuse granulomatous uveitis that usually occurs after open globe injury or intraocular surgery. METHODS: A patient developed SO following therapeutic penetrating keratoplasty (TPK) with cataract extraction in the exciting eye following fungal keratitis. The sympathizing eye presented with only posterior segment findings (exudative retinal detachment) and responded well with oral corticosteroids. RESULTS: Graft remained clear in the left eye and the right eye; the best-corrected visual acuity (BCVA) improved to 0...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27613274/morphological-assessment-of-the-retina-in-uveitis
#16
Michael M Altaweel, Sapna S Gangaputra, Jennifer E Thorne, James P Dunn, Susan G Elner, Glenn J Jaffe, Rosa Y Kim, P Kumar Rao, Susan B Reed, John H Kempen
BACKGROUND: The objective of this study is to describe a system for color photograph evaluation in uveitis and report baseline morphologic findings for the Multicenter Uveitis Steroid Treatment (MUST) Trial. Four-hundred seventy-nine eyes of 255 subjects with intermediate, posterior, and panuveitis had stereoscopic color fundus photographs obtained by certified photographers and evaluated by certified graders using standardized procedures to evaluate morphologic characteristics of uveitis...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27613273/cytomegalovirus-as-a-cause-of-hypertensive-anterior-uveitis-in-immunocompetent-patients
#17
Jin A Choi, Kyu Seop Kim, Younhea Jung, Hae Young Lopilly Park, Chan Kee Park
BACKGROUND: The aims of this study are to investigate the clinical characteristics of patients with anterior hypertensive uveitis and to compare the characteristics between patients in cytomegalovirus (CMV)-positive and CMV-negative groups in their aqueous humor samples. Immunocompetent patients (n = 42) with a history of chronic and/or recurrent hypertensive anterior uveitis underwent ophthalmic examination and serological tests. Among the 42 patients with hypertensive anterior uveitis, aqueous humor sampling was performed in 21, and they were analyzed for viral deoxyribonucleic acids using the polymerase chain reaction (PCR)...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27576870/dexamethasone-intravitreal-implants-in-the-management-of-tubercular-multifocal-serpiginoid-choroiditis
#18
Alex Fonollosa, Sonia Valsero, Joseba Artaraz, Ioana Ruiz-Arruza
BACKGROUND: Continuous progression of lesions despite an adequate treatment has been described in tubercular multifocal serpiginoid choroiditis. Reported treatments for this paradoxical response include systemic steroids, immunosuppressive drugs, and intravitreal methotrexate. We describe the use of dexamethasone intravitreal implants in a patient presenting with this condition. FINDINGS: A 46-year-old woman sought medical attention for scotomas in her left eye...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27528053/microsporidial-stromal-keratitis-and-endophthalmitis-in-an-immunocompetent-patient
#19
Arjun B Sood, Matthew R Debiec, Steven Yeh, Hans E Grossniklaus, J Bradley Randleman
PURPOSE: The purpose of this study is to report a case of microsporidial endophthalmitis after penetrating keratoplasty in a healthy patient and discuss the management. METHODS: This is a case report. RESULTS: A 69-year-old healthy male underwent penetrating keratoplasty for corneal scar secondary to herpes stromal keratitis. He presented with features of acute graft rejection 3 years later. After failure of medical management, a repeat full thickness keratoplasty was performed...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27528052/case-report-providencia-stuartii-conjunctivitis
#20
LETTER
Elliot S Crane, May Shum, David S Chu
PURPOSE: The purpose of this study is to report a case of Providencia stuartii conjunctivitis. METHODS: This study is a retrospective chart review of a patient with persistent conjunctivitis. RESULTS: We report the first case of P. stuartii conjunctivitis. Our patient was an elderly man living in a nursing home who was likely immunocompromised from longstanding diabetes mellitus. A conjunctival swab culture was able to identify the infecting bacteria and its antibiotic susceptibility...
December 2016: Journal of Ophthalmic Inflammation and Infection
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