journal
MENU ▼
Read by QxMD icon Read
search

BMJ Open

journal
https://www.readbyqxmd.com/read/28720619/predictors-of-emergency-department-use-by-adolescents-and-adults-with-autism-spectrum-disorder-a-prospective-cohort-study
#1
Yona Lunsky, Jonathan A Weiss, Melissa Paquette-Smith, Anna Durbin, Ami Tint, Anna M Palucka, Elspeth Bradley
OBJECTIVES: To determine predictors of emergency department (ED) visits in a cohort of adolescents and adults with autism spectrum disorder (ASD). DESIGN: Prospective cohort study. SETTING: Community-based study from Ontario, Canada. PARTICIPANTS: Parents reported on their adult sons and daughters with ASD living in the community (n=284). MAIN OUTCOME MEASURES: ED visits for any reason, ED visits for medical reasons and ED visits for psychiatric reasons over 1 year...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720618/interpretation-of-cis-in-clinical-trials-with-non-significant-results-systematic-review-and-recommendations
#2
Jennifer S Gewandter, Michael P McDermott, Rachel A Kitt, Jenna Chaudari, James G Koch, Scott R Evans, Robert A Gross, John D Markman, Dennis C Turk, Robert H Dworkin
OBJECTIVES: Interpretation of CIs in randomised clinical trials (RCTs) with treatment effects that are not statistically significant can distinguish between results that are 'negative' (the data are not consistent with a clinically meaningful treatment effect) or 'inconclusive' (the data remain consistent with the possibility of a clinically meaningful treatment effect). This interpretation is important to ensure that potentially beneficial treatments are not prematurely abandoned in future research or clinical practice based on invalid conclusions...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720617/protocol-for-an-online-randomised-controlled-trial-to-evaluate-the-clinical-and-cost-effectiveness-of-a-peer-supported-self-management-intervention-for-relatives-of-people-with-psychosis-or-bipolar-disorder-relatives-education-and-coping-toolkit-react
#3
Fiona Lobban, Heather Robinson, Duncan Appelbe, Johanna Barraclough, Emma Bedson, Lizzie Collinge, Susanna Dodd, Sue Flowers, Mahsa Honary, Sonia Johnson, Ceu Mateus, Barbara Mezes, Valerie Minns, Elizabeth Murray, Andrew Walker, Paula Williamson, Catherine Wintermeyer, Steven Jones
INTRODUCTION: Despite clinical guidelines recommendations, many relatives of people with psychosis or bipolar disorder do not currently receive the support they need. Online information and support may offer a solution. METHODS AND ANALYSIS: This single-blind, parallel, online randomised controlled trial will determine clinical and cost-effectiveness of the Relatives Education And Coping Toolkit (REACT) (including an online resource directory (RD)), compared with RD only, for relatives of people with psychosis or bipolar disorder...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720616/concomitant-preterm-birth-and-severe-small-for-gestational-age-birth-weight-among-infants-of-immigrant-mothers-in-ontario-originating-from-the-philippines-and-east-asia-a-population-based-study
#4
Emily Bartsch, Alison L Park, Jennifer Jairam, Joel G Ray
OBJECTIVES: Women from the Philippines form one of the largest immigrant groups to North America. Their newborns experience higher rates of preterm birth (PTB), and separately, small-for-gestational age (SGA) birth weight, compared with other East Asians. It is not known if Filipino women are at elevated risk of concomitant PTB and severe SGA (PTB-SGA), a pathological state likely reflective of placental dysfunction and neonatal morbidity. METHODS: We conducted a population-based study of all singleton or twin live births in Ontario, from 2002 to 2011, among immigrant mothers from the Philippines (n=27 946), Vietnam (n=15 297), Hong Kong (n=5618), South Korea (n=5148) and China (n=42 517)...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720615/assessment-of-the-effectiveness-and-safety-of-ethosuximide-in-the-treatment-of-abdominal-pain-related-to-irritable-bowel-syndrome-ibset-protocol-of-a-randomised-parallel-controlled-double-blind-and-multicentre-trial
#5
Nicolas Kerckhove, Julien Scanzi, Bruno Pereira, Denis Ardid, Michel Dapoigny
INTRODUCTION: Irritable bowel syndrome (IBS) is characterised by the association of abdominal chronic pain with bowel habit disorders in the absence of identifiable organic disease. This is the first reason for consultation in gastroenterology, with an estimated prevalence of 10%-15% in industrialised countries. Although this is a benign gastrointestinal disease, its chronicity profoundly impacts the patient's quality of life and causes considerable health spending. Actual medical treatments are poorly efficient on IBS-related abdominal pain, making it a major public health concern...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720614/effect-of-occupational-safety-and-health-education-received-during-schooling-on-the-incidence-of-workplace-injuries-in-the-first-2-years-of-occupational-life-a-prospective-study
#6
Stephanie Boini, Regis Colin, Michel Grzebyk
OBJECTIVES: This study aimed to determine the effect of occupational safety and health (OSH) education during formal schooling on the incidence of workplace injuries (WIs) in young people starting their careers. We hypothesised that young people who had received OSH education during their schooling would have fewer WIs than those who received no OSH education. Secondary objectives focused on the effect of 'first aid at work' training during schooling and the conditions encountered on arrival in the company (occupational hazard information, safety training and job task training) on WI occurrence...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720613/retrospective-analysis-of-newly-recorded-certifications-of-visual-impairment-due-to-diabetic-retinopathy-in-wales-during-2007-2015
#7
Rebecca L Thomas, Stephen D Luzio, Rachel V North, Sanjiv Banerjee, Antra Zekite, Catey Bunce, David R Owens
OBJECTIVE: The aim of this study was to analyse the changes in new certifications for both sight impairment (SI) and severe sight impairment (SSI, blindness) in Wales due to diabetic retinopathy (DR)/maculopathy between 2007 and 2015. RESEARCH DESIGN AND METHODS: This is a retrospective analysis of annual data of new certifications for visual impairment and blindness (Certificate of Vision Impairment) for England and Wales derived from the national database provided by the Certifications Office, Moorfields Eye Hospital, over a period of 8 years from 2007...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720612/translating-staff-experience-into-organisational-improvement-the-heads-up-stepped-wedge-cluster-controlled-non-randomised-trial
#8
Samuel Pannick, Thanos Athanasiou, Susannah J Long, Iain Beveridge, Nick Sevdalis
OBJECTIVES: Frontline insights into care delivery correlate with patients' clinical outcomes. These outcomes might be improved through near-real time identification and mitigation of staff concerns. We evaluated the effects of a prospective frontline surveillance system on patient and team outcomes. DESIGN: Prospective, stepped wedge, non-randomised, cluster controlled trial; prespecified per protocol analysis for high-fidelity intervention delivery. PARTICIPANTS: Seven interdisciplinary medical ward teams from two hospitals in the UK...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28720611/prevalence-and-risk-factors-of-latent-tuberculosis-infection-in-africa-a-systematic-review-and-meta-analysis-protocol
#9
Tariro J Basera, Jabulani Ncayiyana, Mark E Engel
INTRODUCTION: Latent tuberculosis infection (LTBI) remains a major public health problem and one of the major contributors to the pool of active tuberculosis cases. The true burden of LTBI in Africa is not known. Early modelling studies estimate that over 33% of the world's population is infected with latent tuberculosis. We propose conducting a systematic review and a meta-analysis to evaluate the burden and risk factors of LTBI in Africa reported in studies from 2000 to 2017. METHODS AND ANALYSIS: We will include cross-sectional studies, cohort studies and case-control studies estimating either tuberculin skin test (TST) or interferon-gamma release assay (IGRA) confirmed prevalence of LTBI and associated risk factors among people in African countries...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716798/corrections-systematic-review-of-systematic-reviews-of-non-pharmacological-interventions-to-treat-behavioural-disturbances-in-older-patients-with-dementia-the-senator-ontop-series
#10
LETTER
https://www.readbyqxmd.com/read/28716797/a-pragmatic-phase-iii-multisite-double-blind-placebo-controlled-parallel-arm-dose-increment-randomised-trial-of-regular-low-dose-extended-release-morphine-for-chronic-breathlessness-breathlessness-exertion-and-morphine-sulfate-beams-study-protocol
#11
David Currow, Gareth John Watts, Miriam Johnson, Christine F McDonald, John O Miners, Andrew A Somogyi, Linda Denehy, Nicola McCaffrey, Danny J Eckert, Philip McCloud, Sandra Louw, Lawrence Lam, Aine Greene, Belinda Fazekas, Katherine C Clark, Kwun Fong, Meera R Agar, Rohit Joshi, Sharon Kilbreath, Diana Ferreira, Magnus Ekström
INTRODUCTION: Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended- release (ER) oral morphine. A recent large phase III study suggests the subgroup most likely to benefit have chronic obstructive pulmonary disease (COPD) and modified Medical Research Council breathlessness scores of 3 or 4. This protocol is for an adequately powered, parallel-arm, placebo-controlled, multisite, factorial, block-randomised study evaluating regular ER morphine for chronic breathlessness in people with COPD...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716796/clinical-and-cost-effectiveness-of-progressive-exercise-compared-with-best-practice-advice-with-or-without-corticosteroid-injection-for-the-treatment-of-rotator-cuff-disorders-protocol-for-a-2x2-factorial-randomised-controlled-trial-the-grasp-trial
#12
Sally Hopewell, David J Keene, Michael Maia Schlüssel, Melina Dritsaki, Susan Dutton, Andrew Carr, William Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Hessam Soutakbar, Peter Heine, Lucy Cureton, Karen Barker, Sarah E Lamb
INTRODUCTION: Shoulder pain is very common, with around 70% of cases due to disorders of the rotator cuff. Despite widespread provision of physiotherapy, there is uncertainty about which type of exercise and delivery mechanisms are associated with best outcomes. There is also uncertainty around the long-term benefits and harms of corticosteroid injection therapy, which is often used in addition to physiotherapy. The Getting it Right: Addressing Shoulder Pain trial will assess the clinical and cost-effectiveness of individually tailored, progressive exercise compared with best practice advice, with or without corticosteroid injection, in adults with a rotator cuff disorder...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716795/the-magnitude-of-and-factors-associated-with-loss-to-follow-up-among-patients-treated-for-sexually-transmitted-infections-a-multilevel-analysis
#13
Mache Tsadik, Yemane Berhane, Alemayehu Worku, Wondwossen Terefe
OBJECTIVES: The loss to follow-up (LTFU) among patients attending care for sexually transmitted infections (STIs) in Sub-Saharan Africa is a major barrier to achieving the goals of the STI prevention and control programme. The objective of this study was to investigate individual- and facility-level factors associated with LTFU among patients treated for STIs in Ethiopia. METHODS: A prospective cohort study was conducted among patients attending care for STIs in selected facilities from January to June 2015 in the Tigray region of Ethiopia...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716794/incidence-of-live-attenuated-influenza-vaccine-administration-beyond-expiry-date-in-children-and-adolescents-aged-2-17-years-in-the-uk-a-population-based-cohort-study
#14
Herve Caspard, Robert P Wise, Amy Steffey, Robert S Brody
OBJECTIVES: To estimate the proportion of live-attenuated influenza vaccine (LAIV) doses administered beyond expiry date in children and adolescents during influenza seasons 2013-2014 and 2014-2015 in the UK. DESIGN: This was a retrospective cohort study. Two cohorts of children and adolescents who received LAIV from 1 September 2013 to 31 March 2014 and from 1 September 2014 to 31 March 2015 and aged 2-17 years at time of LAIV administration were identified from the Clinical Practice Research Datalink (CPRD)...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716793/the-realities-of-partnership-in-person-centred-care-a-qualitative-interview-study-with-patients-and-professionals
#15
Axel Wolf, Lucy Moore, Doris Lydahl, Öncel Naldemirci, Mark Elam, Nicky Britten
OBJECTIVE: Although conceptual definitions of person-centred care (PCC) vary, most models value the involvement of patients through patient-professional partnerships. While this may increase patients' sense of responsibility and control, research is needed to further understand how this partnership is created and perceived. This study aims to explore the realities of partnership as perceived by patients and health professionals in everyday PCC practice. DESIGN: Qualitative study employing a thematic analysis of semistructured interviews with professionals and patients...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716792/influence-of-family-history-on-the-willingness-of-outpatients-to-undergo-genetic-testing-for-salt-sensitive-hypertension-a-cross-sectional-study
#16
Taro Takeshima, Masanobu Okayama, Ryusuke Ae, Masanori Harada, Eiji Kajii
OBJECTIVES: It is unclear whether family medical history influences the willingness to undergo genetic testing. This study aimed to determine how family history affected the willingness to undergo genetic testing for salt-sensitive hypertension in patients with and without hypertension. DESIGN: Cross-sectional study using a self-administered questionnaire. SETTING: Six primary care clinics and hospitals in Japan. PARTICIPANTS: Consecutive 1705 outpatients aged >20 years, 578 of whom had hypertension...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716791/factors-associated-with-nicotine-dependence-during-methadone-maintenance-treatment-findings-from-a-multisite-survey-in-vietnam
#17
Huyen Phuc Do, Long Hoang Nguyen, Nhung Phuong Thi Nguyen, Chau Ngo, Huong Lan Thi Nguyen, Giang Tong Le, Linh Khanh Nguyen, Cuong Tat Nguyen, Bach Xuan Tran, Huong Thi Le, Thuc Minh Thi Vu, Huong Thu Thi Phan, Tho Dinh Tran, Carl A Latkin, Michael P Dunne
OBJECTIVES: Smoking is associated with adverse health outcomes among drug users, including those in treatment. To date, however, there has been little evidence about smoking patterns among people receiving opioid-dependence treatment in developing countries. We examined self-reported nicotine dependence and associated factors in a large sample of opioid-dependent patients receiving methadone maintenance treatment (MMT) in northern Vietnam. SETTING: Five clinics in Hanoi (urban area) and Nam Dinh (rural area)...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716790/human-papillomavirus-prevalence-and-genotype-distribution-among-young-women-and-men-in-maputo-city-mozambique
#18
Viegas Edna Omar, Augusto Orvalho, Ismael Nália, Kaliff Malin, Lillsunde-Larsson Gabriella, Ramqvist Torbjörn, Nilsson Charlotta, Falk Kerstin, Osman Nafissa, Jani Ilesh Vindorai, Andersson Sören
OBJECTIVES: Human papillomavirus (HPV) is a well-known cause of cervical cancer, the second most frequent cancer in female African populations. This study aimed at determining the prevalence of HPV infections and the genotype distribution in young adults aged 18-24, in Maputo city, Mozambique, and to assess the suitability of commercially available HPV vaccines. METHODS: This cross-sectional study was conducted between 2009 and 2011 at a youth clinic in Maputo Central Hospital...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716789/identification-of-the-delivery-of-cognitive-behavioural-therapy-for-psychosis-cbtp-using-a-cross-sectional-sample-from-electronic-health-records-and-open-text-information-in-a-large-uk-based-mental-health-case-register
#19
Craig Colling, Lauren Evans, Matthew Broadbent, David Chandran, Thomas J Craig, Anna Kolliakou, Robert Stewart, Philippa A Garety
OBJECTIVE: Our primary objective was to identify cognitive behavioural therapy (CBT) delivery for people with psychosis (CBTp) using an automated method in a large electronic health record database. We also examined what proportion of service users with a diagnosis of psychosis were recorded as having received CBTp within their episode of care during defined time periods provided by early intervention or promoting recovery community services for people with psychosis, compared with published audits and whether demographic characteristics differentially predicted the receipt of CBTp...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716788/long-term-time-trends-in-incidence-survival-and-mortality-of-lymphomas-by-subtype-among-adults-in-manitoba-canada-a-population-based-study-using-cancer-registry-data
#20
Xibiao Ye, Salaheddin Mahmud, Pamela Skrabek, Lisa Lix, James B Johnston
OBJECTIVE: To examine 30-year time trends in incidence, survival and mortality of lymphomas by subtype in Manitoba, Canada. METHODS: Lymphoma cases diagnosed between 1984 and 2013 were classified according to the 2008 WHO classification system for lymphoid neoplasms. Death data (1984-2014) were obtained from the Manitoba Vital Statistics Agency. To examine time trends in incidence and mortality, we used joinpoint regression to estimate annual percentage change and average annual percentage change...
July 17, 2017: BMJ Open
journal
journal
43426
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"