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Journal of Mid-life Health

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https://www.readbyqxmd.com/read/28706413/virilization-in-a-postmenopausal-female-due-to-androgen-secreting-ovarian-dermoid-cyst
#1
Murali Subbaiah, Gowri Dorairajan, Debasis Gochhait, G Vijayalakshmi
Virilizing ovarian dermoid cysts are very rare. The source of androgen in these cysts may be tumors such as Sertoli-Leydig cell tumor or Leydig cell hyperplasia. A 52-year-old postmenopausal female with virilization was found to have an ovarian dermoid cyst on ultrasound. Her serum testosterone levels were elevated. Leydig cell hyperplasia within the dermoid cyst was found to be the source of androgen in this patient.
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706412/uterine-adenofibroma-an-unsual-cause-of-nonpuerperal-uterine-inversion-in-postmenopausal-female
#2
Latika Chawla, Richa Vatsa, Kallol Kumar Roy, Sunesh Kumar
Uterine adenofibroma is an extremely rare benign mixed mullerian tumor, most often presenting as vaginal mass with pain and abnormal uterine bleeding in postmenopausal females. Nonpuerperal uterine inversion is also an uncommon entity. We present a rare case of nonpuerperal uterine inversion due to a uterine adenofibroma. A 56-year-old postmenopausal female presented to us with bleeding and discharge per vaginum. Examination showed a polyp. Due to associated comorbidities, polypectomy was chosen as management modality failing which laparotomy was done, and the uterus was found to be inverted through the cervix, hysterectomy was done...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706411/toxic-shock-syndrome-within-24-h-of-an-office-hysteroscopy
#3
Nanak Bhagat, Akilandeshwari Karthikeyan, Sanjaya Kalkur
Office hysteroscopy is now a common procedure performed to look at the endometrial cavity and is relatively free of serious complications. A 68-year-old lady, previously fit and well, presented with abdominal pain, rigors, sweats, and vomiting within 24 h of an outpatient hysteroscopy for postmenopausal bleeding. She was diagnosed with streptococcal toxic shock syndrome (STSS) due to Group A beta-hemolytic streptococci. She was managed in the Intensive Care Unit, with inotropic and antibiotic support. She recovered eventually and was discharged home with oral antibiotics...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706410/coexisting-brenner-tumor-and-endometrial-carcinoma
#4
Mitakshara Sharma, Babita Khangar, Varuna Mallya, Nita Khurana, Sangeeta Gupta
Brenner tumor is a rare ovarian neoplasm that is seen in women of the fifth to sixth decade. Classified as benign, borderline, and malignant, these tumors may be associated with estrogen production, thus altering the estrogen-progesterone ratio. High estrogen stimulates the endometrium and this is responsible for producing various pathologies, namely, hyperplasia, atypia, and carcinoma. Very few case reports have been published highlighting the same. A case report is being presented here of a coexisting Brenner tumor and well-differentiated endometrial carcinoma in a 55-year-old nulliparous postmenopausal woman...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706409/determinants-of-awareness-and-practice-of-breast-self-examination-among-rural-women-in-trichy-tamil-nadu
#5
Hemalatha Kumarasamy, A M Veerakumar, S Subhathra, Y Suga, R Murugaraj
INTRODUCTION: Breast cancer is the most common cancer among women worldwide, and it can be detected at an early stage through self-examination which increases the chance of survival. This study aimed to assess knowledge and practice of breast self-examination (BSE) among females in a rural area of Trichy district. METHODOLOGY: This community-based, cross-sectional study was carried out among a total sample of 200 women in rural area of Trichy. The participants were interviewed using a structured interviewer-administered questionnaire to obtain information on their sociodemographic characteristics, awareness on breast cancer, and knowledge, attitude, practice of BSE...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706408/factors-affecting-quality-of-life-in-breast-cancer-patients-a-descriptive-and-cross-sectional-study-with-review-of-literature
#6
Neelam Sharma, Abhishek Purkayastha
OBJECTIVE: This descriptive and cross-sectional study was undertaken to determine the factors affecting quality of life (QOL) in breast cancer patients. METHODS: We collected data from 60 patients of carcinoma breast post modified radical mastectomy on radiotherapy in a tertiary care hospital. We included volunteered patients with a signed informed consent and at least 70 Karnofsky Performance Scale points. The data was gathered by interview technique using EORTC QLQ-C30 and QLQ-BR23 (Breast Cancer Module)...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706407/incidence-of-oral-lichen-planus-in-perimenopausal-women-a-cross-sectional-study-in-western-uttar-pradesh-population
#7
Ravi Prakash Sasankoti Mohan, Akanksha Gupta, Nagaraju Kamarthi, Sangeeta Malik, Sumit Goel, Swati Gupta
BACKGROUND: Hormonal fluctuations during menopause lead to endocrine changes in women, especially in their sex steroid hormone production. Studies have documented the role of estrogen and progesterone (Pg) on autoimmune disorders such as multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis. Lichen planus (LP), an autoimmune disorder, seen frequently in perimenopausal women, may also get affected by sex steroid hormones, but no direct relationship has been established yet...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706406/health-related-factors-associated-with-adherence-to-breast-cancer-screening
#8
Joke Schoofs, Katrien Krijger, Jan Vandevoorde, Dirk Devroey
INTRODUCTION: In Belgium, an effective preventive program for breast cancer exists but as in many countries to few women participates in the screening. This study aims to describe the factors that affect the participation in the national breast cancer screening program. METHODS: The participants were aged between 50 and 69 years and were recruited during an exhibition at the Brussels Exhibition Centre. Medical history and health-related parameters of the participants were recorded...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706405/vulvar-lichen-sclerosus-et-atrophicus
#9
REVIEW
Pragya Ashok Nair
Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis characterized by ivory-white plaques or patches with glistening surface commonly affecting the vulva and anus. Common symptoms are irritation, soreness, dyspareunia, dysuria, and urinary or fecal incontinence. Anogenital lichen sclerosus (LS) is characterized by porcelain-white atrophic plaques, which may become confluent extending around the vulval and perianal skin in a figure of eight configuration. Thinning and shrinkage of the genital area make coitus, urination, and defecation painful...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28706404/dry-eye-syndrome-in-menopause-and-perimenopausal-age-group
#10
REVIEW
Travis Peck, Leslie Olsakovsky, Shruti Aggarwal
Dry eye disease (DED) is a multifactorial ocular surface disease that causes symptoms of ocular pain, discomfort, and decreased visual acuity. It significantly affects quality of life of patients. It is more prevalent in the females and is being specifically in the menopausal and postmenopausal age group. This is believed to be due to the changes in balance of sex hormones. Sex hormones - estrogens and androgens - influence production of all components of the tear film including aqueous layer, lipid, and mucin...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458480/coexisting-leiomyomata-peritonealis-disseminata-and-ovarian-leiomyoma
#11
Babita Khangar, Varuna Mallya, Nita Khurana, Poonam Sachdeva, Swati Kashyap
Leiomyoma is the most common tumor seen affecting women mostly of reproductive age groups. It is composed of smooth muscle cells that are positive for smooth muscle actin on immunohistochemistry. Leiomyomata peritonealis disseminata (LPD) is characterized by nodules that stud the peritoneum. It is seen in association with hormone-producing ovarian tumors and coexisting leiomyomas of the uterus. Association with mesenteric leiomyomas has been reported. Ovarian leiomyomas are very rare tumors of the ovary and coexisting LPD with ovarian leiomyomas has not been reported before...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458479/gestational-gigantomastia-a-systematic-review-of-case-reports
#12
Mishu Mangla, Deepak Singla
INTRODUCTION: Gestational gigantomastia (GG) is a rare disease characterized by diffuse, extreme, and incapacitating enlargement of one or both breasts during pregnancy. Although benign, it can lead to a great social, emotional, and physical disability. A good and complete knowledge regarding this rare but distressing clinical situation is a must among all practicing physicians especially obstetricians. MATERIALS AND METHODS: A systematic review of all the case reports and short case series, published in the English language in various databases in the last 40 years, i...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458478/efficacy-of-transcutaneous-electrical-nerve-stimulation-in-the-treatment-of-chronic-pelvic-pain
#13
Nidhi Sharma, Kaja Rekha, Jayashree K Srinivasan
BACKGROUND: Chronic pelvic pain is prevalent in 2% of women population globally. The etiology is multifactorial. Even in the absence of pelvic pathology, there is a subgroup of women who do not respond to analgesic and anti-inflammatory therapy. Chronic pelvic pain can be inhibited by direct inhibition of impulses in the preganglionic afferent neuron by closing the hypothetical gate in the dorsal horn of the spinal cord. Transcutaneous electrical nerve stimulation (TENS) is based on the gate control theory of abolishing the painful stimuli by providing simultaneous inputs in larger myelinated nerve fibers...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458477/role-of-vitamin-d-in-urogenital-health-of-geriatric-participants
#14
Harmanpreet Kaur, Ripan Bala, Madhu Nagpal
INTRODUCTION: Role of Vitamin D is very well known for the functioning of many body organs. However, its role in the postmenopausal women in relation to various genitourinary disorders has been recognized recently. The main objective of this study was to evaluate role of Vitamin D in vaginal health, prolapse, bladder and bowel function, and bacterial vaginosis (BV). MATERIALS AND METHODS: This was a randomized controlled study in which 200 geriatric female patients of 65-78 years of age divided into two groups comprising study and control group with 100 participants in each...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458476/quality-of-life-among-menopausal-women-a-community-based-study-in-a-rural-area-of-west-bengal
#15
Nabarun Karmakar, Somak Majumdar, Aparajita Dasgupta, Sulagna Das
INTRODUCTION: During menopausal transition, there is a lot of fluctuation in the hormone levels making the peri and postmenopausal women susceptible to various mental and physical disorders. There is considerably lack of awareness about the effects of the menopausal symptoms in women in India. Studies on issues relating to menopause, especially among rural women, are also lacking. With this background, the current study was carried out in a rural area of West Bengal with the objective to assess the quality of life (QOL) of peri-menopausal women...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458475/ormeloxifene-looking-beyond-contraception
#16
Tapasi Pati, Kabita Chanania, Satyabhama Marandi, Jagadish Hansa
AIMS: This study is aimed at finding out a logical solution for perimenopausal menorrhagia in normal or bulky uterus. SETTINGS AND DESIGN: The study is carried out at a tertiary care hospital at Odisha. In our setup, nearly 900 hysterectomies are done per year out of which 60% are for menorrhagia with bulky uterus. SUBJECTS AND METHODS: There were sixty cases of menorrhagia between the ages of 40 and 55 years who completed child bearing treated with ormeloxifene...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458474/hormone-replacement-therapy-reduces-lipid-oxidation-directly-at-the-arterial-wall-a-possible-link-to-estrogens-cardioprotective-effect-through-atherosclerosis-prevention
#17
Carlos Gómez Escalante, Silvia Quesada Mora, Laura Navarro Bolaños
BACKGROUND: The first step in atherosclerosis formation is the ingurgitation of an oxidized low-density lipid (LDL) molecule by a macrophage which then turns into a foam cell within the vascular wall and initiates a cascade of inflammatory responses. Could it be that the potential cardioprotective effect observed in women receiving hormone replacement therapy (HRT) is modulated by estrogen's capacity to decrease LDL oxidation in the vascular wall and thus decrease atherosclerotic foam cells? MATERIALS AND METHODS: Thirty-four adult female Wistar rats were divided into three groups...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28458473/screening-methods-clinical-breast-examination-and-mammography-to-detect-breast-cancer-in-women-aged-40-49-years
#18
Navneet Takkar, Suman Kochhar, Priyanka Garg, A K Pandey, Usha Rani Dalal, Uma Handa
OBJECTIVE: The aim of this study is to detect breast cancer rate, nodal status, tumor size, and associated risk factors using clinical breast examination (CBE) and mammography as screening tools in women aged 40-49 years. MATERIALS AND METHODS: A total of 500 women were screened in a time period of 2 years, between the ages of 40-49 years for breast cancer. Screening tools used were CBE and mammography. Clinical history and risk factors related to breast cancer were recorded...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28096645/peri-and-post-menopausal-women-with-complex-adnexal-masses-ascites-and-raised-ca-125-is-it-ovarian-cancer-or-tuberculosis
#19
Rashmi Bagga, Tanuja Muthyala, Subhas Chandra Saha, Shalini Gainder, Pradip Kumar Saha, Radhika Srinivasan, Arvind Rajwanshi, Nalini Gupta
Pelvic and peritoneal tuberculosis may resemble advanced ovarian cancer due to the presence of ascites, complex adnexal masses, peritoneal deposits and raised CA-125 level, especially in peri- and postmenopausal women. Other common features among women with these two conditions are abdominal pain and distension, weight loss and reduced appetite. As the treatment of pelvic-peritoneal tuberculosis is completely different from that of ovarian cancer, it is important to reach a correct diagnosis. Sometimes women with pelvic-peritoneal tuberculosis may be subjected to a laparotomy for suspected ovarian cancer which is likely to increase their morbidity...
October 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28096644/postmenopausal-hyperandrogenism-of-ovarian-origin-a-clinicopathologic-study-of-five-cases
#20
S Ajith, George Beena, Nitu Mariam Mathew, E K Omana
In postmenopausal women presenting with virilization and elevated testosterone levels, laparoscopic salpingo-oophorectomy should be considered after exclusion of adrenal causes. A clinicopathological study was conducted among those women who presented with features of hyperandrogenism in our postmenopausal clinic over a period of 2 years. Relevant past medical and surgical histories were elicited. Basic hormonal evaluation and radiological imaging were done. Laparoscopic bilateral salpingo-oophorectomy was done...
October 2016: Journal of Mid-life Health
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