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Neurology International

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https://www.readbyqxmd.com/read/30069292/quantitative-assessment-of-gait-parameters-in-people-with-parkinson-s-disease-in-laboratory-and-clinical-setting-are-the-measures-interchangeable
#1
Massimiliano Pau, Federica Corona, Roberta Pili, Carlo Casula, Marco Guicciardi, Giovanni Cossu, Mauro Murgia
This study aimed to investigate possible differences in spatio-temporal gait parameters of people with Parkinson's Disease (pwPD) when they are tested either in laboratory using 3D Gait Analysis or in a clinical setting using wearable accelerometers. The main spatio-temporal gait parameters (speed, cadence, stride length, stance, swing and double support duration) of 31 pwPD were acquired: i) using a wearable accelerometer in a clinical setting while wearing shoes (ISS); ii) same as condition 1, but barefoot (ISB); iii) using an optoelectronic system (OES) undressed and barefoot...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069291/vertebral-artery-dissection-stroke-in-evolution-presented-with-postural-headache-as-initial-manifestation
#2
Yen-Chung Chen, Yang-Hao Ou, Ming-Che Chang, Wei-Liang Chen, Chih-Ming Lin
In young adult, the most common etiology of acute ischemic brain infarction are arterial dissections and cardiogenic embolic stroke. Vertebral artery dissection without preceding trauma history is quite rare in young ischemic stroke patients. Postural headache is even more atypical presentation for vertebral artery dissection. It is often misdiagnosed as spontaneous intracranial hypotension. We described a 37-year-old male suffering from acute onset postural headache with stroke in evolution during hospitalization...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069290/posterior-cortical-atrophy-a-rare-variant-of-alzheimer-s-disease
#3
Michael A Meyer, Stephen A Hudock
Posterior cortical atrophy is a rare condition first described in 1988 involving progressive degeneration and atrophy of the occipital cortex, often recognized after an unexplained homonymous hemianopsia may be discovered. We report a case in association with Alzheimer's disease in a 77-year-old female, who underwent brain single-photon emission computed tomography as well brain positron emission tomography using Florbetapir to further evaluate progressive cognitive decline. The patient had also been followed in Ophthalmology for glaucoma, where a progressive unexplained change in her visual field maps were noted over one year consistent with a progressive right homonymous hemianopsia...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069289/prevalence-of-neurological-complications-associated-with-zika-virus-in-a-brazilian-metropolis
#4
Kattiucy Gabrielle da Silva Brito, Edarlan Barbosa Dos Santos, Liliane Dos Santos Maia Lucas, Marco Orsini, Rossano Fiorelli, Silmar Teixeira, Carla Ayres, Luan Correia, Victor Hugo Bastos, Eduardo Trajano, Carlos Eduardo Cardoso, Marcos R G de Freitas, Antônio Marcos da Silva Catharino
The aim of this paper is to study the prevalence of Zika Virus (ZIKV) and the index of its neurological complications. This is a quantitative, cross-sectional epidemiological study. Data were collected through the compulsory notification of suspected ZIKV and its neurological alterations cases. 113 suspected ZIKV cases were reported, most of them in the summer, with a higher prevalence of females and in the fourth decade of life. Among the neurological changes, 15 Guillain-Barré Syndrome cases were reported, with one registered death...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069288/cognitive-impairment-in-neuromuscular-diseases-a-systematic-review
#5
Marco Orsini, Ana Carolina, Andorinho de F Ferreira, Anna Carolina Damm de Assis, Thais Magalhães, Silmar Teixeira, Victor Hugo Bastos, Victor Marinho, Thomaz Oliveira, Rossano Fiorelli, Acary Bulle Oliveira, Marcos R G de Freitas
Neuromuscular diseases are multifactorial pathologies characterized by extensive muscle fiber damage that leads to the activation of satellite cells and to the exhaustion of their pool, with consequent impairment of neurobiological aspects, such as cognition and motor control. To review the knowledge and obtain a broad view of the cognitive impairment on Neuromuscular Diseases. Cognitive impairment in neuromuscular disease was explored; a literature search up to October 2017 was conducted, including experimental studies, case reports and reviews written in English...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069287/allgrove-syndrome-and-motor-neuron-disease
#6
Marcos R G de Freitas, Marco Orsini, Alexandra Prufer de Queiroz Campos Araújo, Luiz João Abraão Jr, Gilberto Miranda Barbosa, Marcondes C França, Luan Correia, Victor Hugo Bastos, Eduardo Trajano, Mauricio da Sant'Anna Jr
Allgrove or triple A syndrome (AS or AAA) is a rare autosomal recessive syndrome with variable phenotype due to mutations in AAAS gene which encodes a protein called ALADIN. Generally, it's characterized by of adrenal insufficiency in consequence of adrenocorticotropic hormone (ACTH) resistance, besides of achalasia, and alacrimia. Neurologic features are varied and have been the subject of several case reports and reviews. A few cases of Allgrove syndrome with motor neuron disease have been already described...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/30069286/efficacy-of-physical-therapy-associated-with-botulinum-toxin-type-a-on-functional-performance-in-post-stroke-spasticity-a-randomized-double-blinded-placebo-controlled-trial
#7
Antonio Prazeres, Marília Lira, Paula Aguiar, Larissa Monteiro, Ítalo Vilasbôas, Ailton Melo
The aim was to investigate if botulinum toxin type A (BTx-A) associated with physical therapy is superior to physical therapy alone in post stroke spasticity. A randomized, double-blinded controlled trial was performed in a rehabilitation unit on Northeastern, Brazil. Patients with post stroke spasticity were enrolled either to BTx-A injections and a pre-defined program of physical therapy or saline injections plus physical therapy. Primary endpoint was functional performance evaluated through time up and go test, six minutes walking test and Fugl-Meyer scale for upper limb...
May 24, 2018: Neurology International
https://www.readbyqxmd.com/read/29844894/a-giant-cholesteatoma-of-the-mastoid-extending-into-the-foramen-magnum-a-case-report-and-review-of-literature
#8
Seidu A Richard, Li Qiang, Zhi Gang Lan, Yuekang Zhang, Chao You
Cholesteatomas are very rare benign, progressive lesions that have embryologic derivation and usually result in progressive exfoliation and confinement of squamous epithelium behind an intact or preciously infected tympanic membrane. To the best of our understanding no reports demonstrates the extension of cholesteatoma from the temporal bone into the foramen magnum. We therefore present a case of cholesteatoma extending down into the foramen magnum. We report a case of 67- year-old man with a giant cholesteatoma extending into the foramen magnum without substantial destruction of the mastoid and petrous temporal bones...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844893/stroke-networks-and-telemedicine-an-italian-national-survey
#9
Laura Bernetti, Graziamaria Nuzzaco, Francesco Muscia, Alessio Gamboni, Marialuisa Zedde, Paolo Eusebi, Mauro Zampolini, Francesco Corea
Stroke is the leading cause of disability and death. Nowadays, clinical benefits of stroke units and thrombolysis in ischemic stroke are evidence-based. Also the benefit of endovascular treatment for acute ischemic stroke has been established. Telemedicine has been used to improve access to care by allowing a neurologist at a remote location to interact with the patient and their family members. Prior studies have shown that the use of telemedicine for acute ischemic stroke is not only safe and effective, but it also increases the utilization of tPA, improving patient outcomes...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844892/glioma-research-early-detection-of-a-downward-trend-in-publication-productivity
#10
Michael A Meyer
Global publication productivity for brain tumors was examined on a annual basis and compared to other neurologic disorders including stroke, epilepsy and Alzheimer's disease. An early downward trend is suggested for 2016; possible links to fluctuations in funding is discussed.
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844891/glioblastoma-multiforme-subterfuge-as-acute-cerebral-hemorrhage-a-case-report-and-literature-review
#11
Seidu A Richard, Yunxia Ye, Hao Li, Lu Ma, Chao You
Hemorrhagic related Glioblastoma multiforme (GBM) are rare and characterizes with severe clinical scuffle. The etiology of this presentation although not well known is believed to be multifactorial. We present a case as well as review on the pathogenesis of evolution of the hematoma into ring enhancing features of GBM on imaging studies. We present a case of 28 years old man who suddenly went into coma for 9 hours preceded with seizures that latest for 10 minutes. He had no focal neurological signs. CT-Scans images indicated acute cerebral hemorrhage near the frontal horn of the left ventricle with brain edema about the hemorrhagic lesion and MRI done a week later revealed a cerebral ring enhancing lesion...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844890/multilingual-website-and-cyberconsultations-for-oromandibular-dystonia
#12
Kazuya Yoshida
Oromandibular dystonia is a focal dystonia that manifests as involuntary masticatory and/or tongue muscle contractions. This movement disorder is frequently misdiagnosed as a temporomandibular disorder. Hence, it would be useful to establish a method that makes it possible for patients with the condition to find appropriate medical institutions by themselves. The author produced a website Involuntary movements of the stomatognathic region (https://sites. google.com/site/oromandibulardystoniaenglish/) for patients with oromandibular dystonia, which is available in twenty languages...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844889/pantothenate-kinase-associated-neurodegeneration-clinical-aspects-diagnosis-and-treatments
#13
Saeed Razmeh, Amir Hassan Habibi, Maryam Orooji, Elham Alizadeh, Karim Moradiankokhdan, Behroz Razmeh
Pantothenate Kinase-Associated Neurodegeneration (PKAN) is an autosomal recessive disorder characterized by a mutation in the PANK 2 gene. The clinical presentation may range from only speech disorder to severe generalized dystonia, spasticity, Visual loss, dysphagia and dementia. The hallmark of this disease is eyes of the tiger sign in the medial aspect of bilateral globus pallidus on T2-weighted MRI that is a hyperintense lesion surrounded by hypointensity. Common treatments for PKAN disease include anticholinergics, botulinum toxin, Oral and Intrathecal baclofen, Iron chelation drugs and surgical procedures such as ablative pallidotomy or thalamotomy, Deep brain stimulation...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844888/migraine-incorrect-self-management-for-a-disabling-disease
#14
Giovanna Viticchi, Lorenzo Falsetti, Marco Bartolini, Laura Buratti, Alfio Ulissi, Maurizio Baldassari, Leandro Provinciali, Mauro Silvestrini
Migraine is an economically and socially relevant pathology but patients' consciousness and consequently a proper management is often unsatisfactory. In this study, we aimed to evaluate the disease awareness, the general approach and the impact on working activity in a population of headache-affected hospital workers. During an 18-month period, hospital workers responded to a questionnaire investigating headache presence, characteristics and awareness. Specific attention was paid to define headache impact on working activities...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844887/risk-stratification-in-laminopathies-and-emery-dreifuss-muscular-dystrophy
#15
Abdallah Fayssoil
Laminopathies are genetic disorders due to gene mutation encoding for proteins of the nuclear envelope. Patients are at risk of conduction defect, arrhythmia, sudden death and heart failure. The authors summarize predictive factors for cardiac events reported in the literature in this group of disease.
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29844886/measuring-stroke-patients-exercise-preferences-using-a-discrete-choice-experiment
#16
Wolfgang Geidl, Katja Knocke, Wilfried Schupp, Klaus Pfeifer
Physical activity post stroke improves health, yet physical inactivity is highly prevalent. Tailored exercise programs considering physical activity preferences are a promising approach to promote physical activity. Therefore, this study seeks to measure exercise preferences of stroke survivors. Stroke survivors conducted a discrete choice experiment (DCE). DCE was presented in a face-to-face interview where patients had to choose eight times between two different exercise programs. Exercise programs differed by characteristics, with the six attributes under consideration being social situation, location, type of exercise, intensity, frequency, and duration...
March 30, 2018: Neurology International
https://www.readbyqxmd.com/read/29619160/clinical-features-and-electrocardiogram-parameters-in-parkinson-s-disease
#17
Hitoshi Mochizuki, Nobuyuki Ishii, Kazutaka Shiomi, Masamitsu Nakazato
We investigated the relation between clinical features and electrocardiogram (ECG) parameters in patients with Parkinson's disease (PD). One hundred and fifty-six PD patients were enrolled. Their clinical features [body mass index (BMI), age, disease duration, and disease stage] and ECG parameters [RR, PR, QRS, and QT intervals, and heart rate-corrected QT (QTc)] were analyzed. BMI was positively correlated with the PR and QRS intervals in patients with PD. The QRS interval was positively correlated with disease duration and Hoehn and Yahr stage, and the QT interval and QTc were positively correlated with age...
December 11, 2017: Neurology International
https://www.readbyqxmd.com/read/29619159/depression-and-anxiety-as-determinants-of-health-related-quality-of-life-in-patients-with-multiple-sclerosis-united-arab-emirates
#18
Taoufik Alsaadi, Khadija El Hammasi, Tarek M Shahrour, Mustafa Shakra, Lamya Turkawi, Wassim Nasreddine, Seada Kassie, Mufeed Raoof
To study the impact of depression and anxiety on health-related quality of life (HRQOL) in patients with multiple sclerosis (pwMS) in the UAE. All consecutive patients attending the MS clinic over a fourmonth period, October 2014 through February 2015, at Sheikh Khalifa Medical city (SKMC) were asked to complete The World Health Organization quality of life abbreviated scale (WHOQOL-BREF), the Patient Health Questionnaire nine-item (PHQ-9) depression scale, and Generalized Anxiety Disorder seven-item (GAD-7) scale...
December 11, 2017: Neurology International
https://www.readbyqxmd.com/read/29619158/a-pilot-trial-of-deferiprone-in-pantothenate-kinase-associated-neurodegeneration-patients
#19
Mohammad Rohani, Saeed Razmeh, Gholam Ali Shahidi, Elham Alizadeh, Maryam Orooji
Pantothenate kinase-associated neurodegeneration (PKAN) is the most common form of neurodegeneration with brain iron accumulation, it is an autosomal recessive disease due to mutation in PANK 2 on chromosome 20, which causes the accumulation of iron in basal ganglia and production of free radicals that cause degeneration of the cells. Deferiprone is an iron chelator that was used in treatment of thalassemia patients, it can cross the blood-brain barrier and reverse the iron deposition in the brain. Five patients with genetically confirmed PKAN received 15 mg/kg deferiprone twice daily...
December 11, 2017: Neurology International
https://www.readbyqxmd.com/read/29109855/miller-fisher-syndrome-with-sinus-arrest
#20
Nobuko Shiraiwa, Mitsumasa Umesawa, Sachiko Hoshino, Tsuyoshi Enomoto, Susumu Kusunoki, Akira Tamaoka, Norio Ohkoshi
No abstract text is available yet for this article.
August 29, 2017: Neurology International
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