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Neurology International

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https://www.readbyqxmd.com/read/28713532/bilateral-cavernous-sinus-thrombosis-as-first-manifestation-of-primary-burkitt-lymphoma-of-the-thyroid-gland
#1
Mehdi Moghaddasi, Mona Nabovvati, Saeed Razmeh
Cavernous sinus thrombosis (CST) is a rare condition that is usually associated with infections, pregnancy, vasculitis and some types of medication, such as the contraceptive pill and paraneoplastic. Primary Burkitt lymphoma (PBL) of the thyroid gland is very uncommon and the clinical description of such cases has been largely limited to case reports. In this paper, we present a case of CST as the first manifestation of PBL of the thyroid gland. To the best of our knowledge, our patient is the first case report of PBL of the thyroid gland that presents with bilateral CST...
June 23, 2017: Neurology International
https://www.readbyqxmd.com/read/28713531/the-effects-of-fasting-during-ramadan-on-the-concentration-of-serotonin-dopamine-brain-derived-neurotrophic-factor-and-nerve-growth-factor
#2
Abdolhossein Bastani, Sadegh Rajabi, Fatemeh Kianimarkani
Neurotransmitters and neurotrophic factors are signaling molecules that play a crucial role in cell proliferation, differentiation, survival and functions of neurons. It is believed that caloric restriction could help the health of the nervous system by affecting the synthesis of neurotrophins and neurotransmitter and oxygen radical metabolism. The objective was to investigate the plasma levels of serotonin, dopamine, brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) in 29 healthy fasted subjects (22 women and 7 men) during the month of fasting in Ramadan...
June 23, 2017: Neurology International
https://www.readbyqxmd.com/read/28713530/are-cerebrospinal-fluid-protein-levels-and-plasma-neutrophil-lymphocyte-ratio-associated-with-prognosis-of-guillain-barr%C3%A3-syndrome
#3
Sevki Sahin, Nilgun Cinar, Sibel Karsidag
Guillain Barré syndrome (GBS) is a post-infectious acute autoimmune polyradiculopathy. Cerebrospinal fluid (CSF) total protein level and plasma neutrophil/lymphocyte ratio (NLR) are related with autoimmune response. We aimed to reach a prognostic indicator for GBS by using electrophysiological findings, protein level of CSF, and plasma NLR based on Medical Research Council (MRC) sum score data. Cases who met diagnostic criteria of GBS and followed at least six months were enrolled in the study. Nerve conduction study (NCS) and lumbar puncture were performed one week after symptom onset...
June 23, 2017: Neurology International
https://www.readbyqxmd.com/read/28713529/somatoform-dissociation-fatigue-severity-and-pain-behavior-compared-in-patients-with-migraine-headache-and-in-healthy-individuals
#4
Ghasem Fattahzadeh-Ardalani, Vida Aghazadeh, Abolfazl Atalu, Vahid Abbasi
The prevalence of migraine in the world is about 15 and 7% among women and men, respectively. The purpose of this study was comparison of somatoform dissociation, fatigue severity and pain behavior in patients with migraine headache and its relationship with coping strategies. This descriptive analytical study has been done on 120 patients with migraine headache and 120 healthy subjects were selected randomly. Data collected by somatoform dissociation questionnaire (SDQ-20), fatigue severity scale, pain behavior scale and coping strategies scale...
June 23, 2017: Neurology International
https://www.readbyqxmd.com/read/28461885/serum-uric-acid-kidney-function-and-acute-ischemic-stroke-outcomes-in-elderly-patients-a-single-cohort-perspective-study
#5
Lorenzo Falsetti, William Capeci, Nicola Tarquinio, Giovanna Viticchi, Mauro Silvestrini, Vania Catozzo, Agnese Fioranelli, Laura Buratti, Francesco Pellegrini
Chronic kidney disease and hyperuricemia have been associated to an increased risk and a worse prognosis in acute ischemic stroke. Several mechanisms, including platelet dysfunction, coagulation disorders, endothelial dysfunction, inflammation, and an increased risk of atrial fibrillation could be implicated. The role of serum uric acid in this setting is still object of debate. We enrolled all the consecutive patients admitted to our department for acute ischemic stroke. Cox regression analysis was used to evaluate the risk of in-hospital death considering serum uric acid levels and all the comorbidities...
February 20, 2017: Neurology International
https://www.readbyqxmd.com/read/28461884/risk-of-unsuccessful-noninvasive-ventilation-for-acute-respiratory-failure-in-heterogeneous-neuromuscular-diseases-a-retrospective-study
#6
Hiroshi Kataoka, Hitoki Nanaura, Kaoru Kinugawa, Yuto Uchihara, Hiroya Ohara, Nobuyuki Eura, Ryogo Syobatake, Nobuhiro Sawa, Kiriyama Takao, Kazuma Sugie, Satoshi Ueno
If invasive ventilation can be avoided by performing noninvasive mechanical ventilation (NIV) in patients with acute respiratory failure (ARF), the disease can be effectively managed. It is important to clarify the characteristics of patients with neuromuscular diseases in whom initial NIV is likely to be unsuccessful. We studied 27 patients in stable neuromuscular condition who initially received NIV to manage fatal ARF to identify differences in factors immediately before the onset of ARF among patients who receive continuous NIV support, patients who are switched from NIV to invasive ventilation, and patients in whom NIV is discontinued...
February 20, 2017: Neurology International
https://www.readbyqxmd.com/read/28286627/subcutaneous-interferon-%C3%AE-1a-administration-by-electronic-auto-injector-is-associated-with-high-adherence-in-patients-with-relapsing-remitting-multiple-sclerosis-in-a-real-life-study
#7
Elina Järvinen, Juha Multanen, Sari Atula
The objective was to investigate adherence measured by an electronic auto-injector device, and self-reported adherence and treatment convenience in subjects with relapsing remitting multiple sclerosis (RRMS), using an electronic auto-injector Rebismart(®) to self-inject interferon β-1a. Thirty one patients with RRMS using the electronic auto-injector Rebismart(®) for self-injecting interferon β-1a subcutaneously three times weekly were included in a real-life clinical multicenter study for 24 weeks in Finland...
February 20, 2017: Neurology International
https://www.readbyqxmd.com/read/28286626/periodic-lateralized-epileptiform-discharges-can-survive-anesthesia-and-result-in-asymmetric-drug-induced-burst-suppression
#8
Edward C Mader, Louis A Cannizzaro, Frank J Williams, Saurabh Lalan, Piotr W Olejniczak
Drug-induced burst suppression (DIBS) is bihemispheric and bisymmetric in adults and older children. However, asymmetric DIBS may occur if a pathological process is affecting one hemisphere only or both hemispheres disproportionately. The usual suspect is a destructive lesion; an irritative or epileptogenic lesion is usually not invoked to explain DIBS asymmetry. We report the case of a 66-year-old woman with new-onset seizures who was found to have a hemorrhagic cavernoma and periodic lateralized epileptiform discharges (PLEDs) in the right temporal region...
February 20, 2017: Neurology International
https://www.readbyqxmd.com/read/28217270/neurological-assessment-and-nerve-conduction-study-findings-in-22-patients-with-alkaptonuria-from-jordan
#9
Omar Alrawashdeh, Mohammad Alsbou, Hamed Alzoubi, Hani Al-Shagahin
Alkaptonuria is a rare metabolic disease characterised by accumulative deposition of homogentisic acid in the connective tissue of the body. This results in early degeneration of tendons, cartilages, heart valves, and other tissues. The main objective of the study is to examine the possibility of the nervous system involvement in patients with alkaptonuria The sample consists of two groups; 22 patients with AKU and 20 controls. A neurological assessment has been carried out including detailed medical history, neurological examination, and a nerve conduction study of the nerves of the dominant hand...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/28217269/common-carotid-artery-occlusion-presenting-with-recurrent-syncopal-episodes
#10
Imran Kader, Steven M Jones, Catherine Harrison, Ferdinand Miteff, Senthil Kumar
Symptomatic common carotid artery (CCA) occlusion is an uncommon occurrence that may require surgical intervention. We aim to describe a case of CCA occlusion that presented with the unusual symptom of recurrent syncope. A 69-year-old lady presented with a history of recurrent syncopal episodes and amaurosis fugax associated with left leg weakness. She was found to have a right CCA occlusion on duplex ultrasound and angiography. She underwent a right common carotid endarterectomy and intraoperative findings revealed a heavily calcified plaque in the CCA just proximal to the bifurcation with organised thrombus filling the CCA proximally...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/28217268/anti-musk-positive-myasthenia-gravis-and-three-semiological-cardinal-signs
#11
André P C Matta, Ana C Andorinho F Ferreira, Arielle Kirmse, Anna Carolina Damm, João Gabriel D I B Farinhas, Mariane D Barbosa, Mayara C M Teles, Camila Fiorelli, Rossano Fiorelli, Osvaldo J M Nascimento, Marco Orsini
Myasthenia gravis (MG) is a relatively uncommon disorder with an annual incidence of approximately 7 to 9 new cases per million. The prevalence is about 70 to 165 per million. The prevalence of the disease has been increasing over the past five decades. This is thought to be due to better recognition of the condition, aging of the population, and the longer life span of affected patients. MG causes weakness, predominantly in bulbar, facial, and extra-ocular muscles, often fluctuating over minutes to weeks, in the absence of wasting, sensory loss, or reflex changes...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/28217267/results-of-the-belgian-sentinel-network-of-general-practitioners-on-the-involvement-of-therapists-in-stroke-rehabilitation
#12
Silke Francois, Viviane Van Casteren, Katrien Vanthomme, Liesbeth Borgermans, Dirk Devroey
This study examines which therapists are involved in the rehabilitation of stroke survivors in Belgium at different points in time. A nationwide registration of stroke patients was provided by 199 and 189 family physicians working in sentinel practices for the years 2009 and 2010 respectively. 326 patients who were diagnosed with stroke were included. Patients with paralysis/paresis received significant more physiotherapy after one month (63%) compared to non-paralysed patients (38%) (P = 0.005). Residing in a nursing home was associated with higher proportions of patients receiving physiotherapy, both after one (P = 0...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/27994829/severe-cold-lower-limbs-in-patients-with-parkinson-s-disease-during-the-summer
#13
Hiroshi Kataoka, Satoshi Ueno
Parkinson's disease (PD) is frequently associated with vasomotor symptoms such as distal cold limbs or sensitivity to cold. Coldness of the lower limbs (COL) usually occurs in winter and is often accompanied by pain, potentially causing difficulty in walking or standing. A standard dopaminergic treatment for such symptoms is yet to be established. We describe two patients with PD, who had severe COL during summer. For example, the patients wore many pairs of socks or used heating appliances in the summer. Severe COL can occur in summertime and can be intolerable or unpleasant, since it can worsen disability...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/27994828/prevalence-of-asymptomatic-neurophysiological-carpal-tunnel-syndrome-in-130-healthy-individuals
#14
Omar Alrawashdeh
Diagnosis of carpal tunnel syndrome (CTS) is frequently confirmed by performing nerve conduction studies. Previous studies demonstrated that abnormal nerve conduction study (NCS) is suggestive of CTS among asymptomatic individuals. However, previous studies included individuals with risk factors for the syndrome. A NCS was performed on the median and ulnar nerves in 130 healthy individuals. About 15% of individuals in this study demonstrated electrodiagnostic evidence of carpal tunnels syndrome. Four cases have shown signs of isolated median neuropathy with normal median sensory component...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/27994827/cervical-spondylotic-myelopathy-what-the-neurologist-should-know
#15
REVIEW
Celmir de Oliveira Vilaça, Marco Orsini, Marco A Araujo Leite, Marcos R G de Freitas, Eduardo Davidovich, Rossano Fiorelli, Stenio Fiorelli, Camila Fiorelli, Acary Bulle Oliveira, Bruno Lima Pessoa
Cervical spondylotic myelopathy is a well-known cause of disability among older people. A significant amount of these patients is asymptomatic. Once the symptoms start, the worsening may follow a progressive manner. We should suspect of spondylotic myelopathy in any individual over 55 years presenting progressive changes in gait or losing fine motor control of the upper limbs. Despite its frequent prevalence, this condition is still neglected and many times confused with other supratentorial lesions regarding diagnostic...
November 2, 2016: Neurology International
https://www.readbyqxmd.com/read/27761229/neurosyphilis-with-normal-pressure-hydrocephalus-and-dementia-paralytica-serial-clinical-laboratory-and-radiological-correlations-in-the-21st-century
#16
Kamille Abdool, Karan Seegobin, Kanterpersad Ramcharan, Adrian Alexander, Leandra Julien-Legen, Stanley Lawrence Giddings, Samuel Aboh, Fidel Rampersad
We report a case of a 46-year-old man presenting with a progressive cognitive decline, ataxic gait, urinary incontinence for 4 months and neuroimaging consistent with normal pressure hydrocephalus. The atypical presentation of a progressively worsening dysphasia and a right hemiparesis dismissed as a vascular event 1 month earlier associated with normal pressure hydrocephalus prompted further investigations confirming neurosyphilis also manifesting as dementia paralytica. Treatment using consensus guidelines led to resumption of activities of daily living...
September 30, 2016: Neurology International
https://www.readbyqxmd.com/read/27761228/hereditary-neuropathy-with-liability-to-pressure-palsies-a-single-center-experience-in-southern-brazil
#17
Paulo José Lorenzoni, Cláudia Suemi Kamoi Kay, Cristiane Cavalet, Raquel C Arndt, Lineu Cesar Werneck, Rosana Herminia Scola
The spectrum of clinical and electrophysiological features in hereditary neuropathy with liability to pressure palsies (HNPP) is broad. We analyze a series of Brazilian patients with HNPP. Correlations between clinical manifestations, laboratory features, electrophysiological analyze, histological and molecular findings were done. In five cases, more than one episode occurred before diagnosis. Median nerve in the carpal tunnel at the wrist, ulnar nerve in its groove at the elbow, fibular nerve in the head of the fibula at the knee, radial nerve in its groove of the humerus and suprascapular nerve in its notch at the supraspinous fossa were found as focal neuropathies...
September 30, 2016: Neurology International
https://www.readbyqxmd.com/read/27761227/the-chronic-encephalopathy-of-parry-romberg-syndrome-and-en-coupe-de-sabre-with-a-31-year-history-in-a-west-indian-woman-clinical-immunologic-and-neuroimaging-abnormalities
#18
Karan Seegobin, Kamille Abdool, Kanterpersad Ramcharan, Haramnauth Dyaanand, Fidel Rampersad
We describe a case of Parry Romberg syndrome/en coupe de sabre in a woman whose disease started as seizures at age 8 but was diagnosed at the age 39. During these 31 years she got married, completed a first degree at university, had two successful pregnancies and has been gainfully employed. The features of generalized tonic-clonic seizures, autoimmune abnormalities, ocular abnormalities, morphea en coup de sabre and brain imaging abnormalities were present. Areas of parietal lobe cerebral calcification were encountered on the computed tomographic scan and bilateral periventricular white matter changes on the magnetic resonance imaging with frontal, temporal and parietal lobe brain atrophy ipsilateral to the facial hemiatrophy...
September 30, 2016: Neurology International
https://www.readbyqxmd.com/read/27761226/injectable-disease-modifying-agents-in-multiple-sclerosis-pattern-of-medication-use-and-clinical-effectiveness
#19
Elina Järvinen, Markus Holmberg, Marja-Liisa Sumelahti
The objective of this study was to assess long-term use, adherence and efficacy of injectable disease modifying agents (DMAs). Multiple Sclerosis (MS) patients diagnosed during 2002-2010 with early treatment start and at least one year in first choice medication were included in a large university district in Finland. Annualized relapse rates (ARR) during each treatment period were studied, and number of switches by medication evaluated. Use of health care facilities during 2002-2010 was assessed. In the study were included 113 MS patients; 15 (13%) switched medication...
September 30, 2016: Neurology International
https://www.readbyqxmd.com/read/27761225/multiple-sclerosis-patients-valuing-their-own-health-status-valuation-and-psychometric-properties-of-the-15d
#20
Ioannis E Dagklis, Vasilis H Aletras, Efthymia Tsantaki, Anastasios Orologas, Dimitrios Niakas
An ongoing debate on decision and cost-utility analyses is whether to use preferences of general public or patients. The aim of this study was to replicate the valuation procedure of the multi-attribute utility generic measure, 15D, using a sample of multiple sclerosis (MS) patients and to assess its psychometric properties. Consecutive outpatient MS patients were recruited from two MS centers in Greece. The three-stage valuation procedure was applied and, with the use of elicited preference weights, an MS patients' algorithm was developed...
September 30, 2016: Neurology International
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