journal
MENU ▼
Read by QxMD icon Read
search

Perspectives in Clinical Research

journal
https://www.readbyqxmd.com/read/29430421/intentional-or-unintentional-it-is-never-alright-to-plagiarize-a-note-on-how-indian-universities-are-advised-to-handle-plagiarism
#1
Natasha Das
No abstract text is available yet for this article.
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430420/drug-safety-alerts-of-pharmacovigilance-programme-of-india-a-scope-for-targeted-spontaneous-reporting-in-india
#2
Prasad Thota, Anusha Thota, Bikash Medhi, Shabir Sidhu, Pramod Kumar, V Kalai Selvan, Gyanendra Nath Singh
Background: The National Coordination Centre-Pharmacovigilance Programme of India (NCC-PvPI), Indian Pharmacopoeia Commission works under the aegis of Ministry of Health and Family Welfare, Government of India. It promotes patient safety in India and also supports postmarketing surveillance programs. Currently, almost hundred thousand case reports are submitted to NCC-PvPI each year through its 250 ADR Monitoring Centers (AMCs) located across India, and India is the one of the top ten contributor countries under WHO-Uppsala Monitoring Centre since 2012 and start issuing drug safety alerts from March 2016...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430419/indian-regulatory-update-january-december-2017
#3
Amita Bhave
This document provides updates in regulatory requirements regarding conduct of clinical trials in India.
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430418/audiovisual-recording-of-the-consenting-process-in-clinical-research-experiences-from-a-tertiary-referral-center
#4
Parvan A Shetty, Mitesh R Maurya, Brinal H Figer, Urmila M Thatte, Nithya J Gogtay
The quality of the written informed consent process is one of the most important aspects of clinical research, as it is the single tool that serves as a metric of autonomy. Several challenges have been identified with the informed consent process in developing countries the most important of which is the ability to assimilate and understand the information presented in the consent form. In India, a unique aspect of the informed consent process is the need for audio-video [AV] recording of the process for vulnerable populations and new chemical entities...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430417/common-pitfalls-in-statistical-analysis-understanding-the-properties-of-diagnostic-tests-part-1
#5
Priya Ranganathan, Rakesh Aggarwal
In this article in our series on common pitfalls in statistical analysis, we look at some of the attributes of diagnostic tests (i.e., tests which are used to determine whether an individual does or does not have disease). The next article in this series will focus on further issues related to diagnostic tests.
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430416/managing-conflict-of-interest-in-ethics-committee
#6
Arun Bhatt
The article discusses conflict of interest (COI) situations and how to manage COI in ethics committee (EC).
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430415/impact-of-data-transparency-scientific-publications
#7
REVIEW
Mohit Joshi, Payal Bhardwaj
Data transparency has been an important aspect of medical research as it helps in enabling evidence-based decisions in medicine which leads to foster trust among the patients and research community alike. Currently, it is one of the key talking points owing to a number of initiatives taken by the pharmaceutical organizations, regulatory bodies, and the other decision enablers of the industry. Thanks to this, there are a number of ways by which a single piece of datum is available through multiple access points, namely, clinical trial disclosures (CTDs), clinical study reports (CSRs), plain language summaries, and scientific publications including abstracts, posters, and manuscripts, to name a few...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430414/pattern-and-impact-of-drugs-targeted-toward-toxicity-amelioration-in-patients-receiving-cancer-chemotherapy
#8
Shruti Singh, Prashant Kumar Singh
Background: Drug therapy today is remarkably safe and efficacious. Still, some drugs - particularly anticancer drugs - are fraught with numerous adverse drug reactions (ADRs), severely jeopardizing quality of life of cancer patients. Fortunately, most of these ADRs are preventable provided adequate prophylactic drugs are administered along with chemotherapy. Aims: The aim of this study is to assess the pattern and impact of cytoprotective prophylactic drugs on anticancer ADRs in patients receiving cancer chemotherapy...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430413/an-evaluation-of-the-impact-of-antidiabetic-medication-on-treatment-satisfaction-and-quality-of-life-in-patients-of-diabetes-mellitus
#9
Richa Chaturvedi, Chetna Desai, Prakruti Patel, Asha Shah, Ram K Dikshit
Aims: This study aims to measure the quality of life (QOL), treatment satisfaction, and tolerability of antidiabetic drugs in patients suffering from type 2 diabetes mellitus (DM). Methods: The prospective, observational study was conducted in consenting patients of type 2 DM attending the outpatient department of a tertiary care hospital in Western India. The QOL instrument for Indian diabetes (QOLID) patients questionnaire and the Diabetes Treatment Satisfaction Questionnaire were administered to all patients at baseline, 3 months, and 6 months of treatment...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430412/study-of-drug-drug-interactions-among-the-hypertensive-patients-in-a-tertiary-care-teaching-hospital
#10
Ansha Subramanian, Mangaiarkkarasi Adhimoolam, Suresh Kannan
Aim: Drug-drug interactions (DDIs) are one of the major but preventable cause of adverse drug reaction. Study of prevalence and prediction of DDIs will make the physician easier to provide better patient care and mitigate patient's harm. Hence, the study was planned to evaluate the potential DDIs among medication prescribed to hypertensive patients in our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among the hypertensive patients in medicine (outpatient/inpatient) department over the period of three months in a tertiary care hospital...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430411/comparison-of-efficacy-and-pharmacoeconomics-of-two-helicobacter-pylori-eradication-regimens-in-peptic-ulcer-disease
#11
Syeda Zaineb Kubra Hussaini, Syeda Zaineb Humaira Hussaini, Ruheena Yasmeen, Bader Unnisa, Aamir Ali Asgar Syed, Md Nematullah Khan, Syed Ibrahim Hassan
Background: Helicobacter pylori , the cause of most peptic ulcer diseases, infects approximately 50% of the population worldwide. Indian data on cost and effectiveness of the standard first-line therapies for H. pylori eradication are scarce. Thus, the present study was aimed at comparing the cost and efficacy of two standard first-line therapies: Regimen I comprising pantoprazole (40 mg) plus amoxicillin (750 mg) plus clarithromycin (500 mg) (PAC) and Regimen II comprising rabeprazole (20 mg) plus amoxicillin (625 mg) plus metronidazole (200 mg) (RAM)...
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29430410/managing-diabetes-patients-in-india-is-the-future-more-bitter-or-less-sweet
#12
EDITORIAL
Viraj Rajadhyaksha
No abstract text is available yet for this article.
January 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109940/erratum-relationship-of-admission-mean-platelet-volume-platelet-distribution-width-and-white-blood-cells-with-st-resolution-in-patients-with-acute-st-segment-elevation-myocardial-infarction-treated-with-streptokinase-without-history-of-previous-cardiovascular
#13
https://www.readbyqxmd.com/read/29109939/is-it-easy-to-be-an-ethics-committee-member-experiences-as-an-ethics-committee-member
#14
Santosh K Chaturvedi
No abstract text is available yet for this article.
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109938/a-day-in-the-life-of-a-pharmacovigilance-case-processor
#15
Ritesh Bhangale, Sayali Vaity, Niranjan Kulkarni
Pharmacovigilance (PV) has grown significantly in India in the last couple of decades. The etymological roots for the word "pharmacovigilance" are "Pharmakon" (Greek for drug) and "Vigilare" (Latin for to keep watch). It relies on information gathered from the collection of individual case safety reports and other pharmacoepidemiological data. The PV data processing cycle starts with data collection in computerized systems followed by complete data entry which includes adverse event coding, drug coding, causality and expectedness assessment, narrative writing, quality control, and report submissions followed by data storage and maintenance...
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109937/common-pitfalls-in-statistical-analysis-measures-of-agreement
#16
Priya Ranganathan, C S Pramesh, Rakesh Aggarwal
Agreement between measurements refers to the degree of concordance between two (or more) sets of measurements. Statistical methods to test agreement are used to assess inter-rater variability or to decide whether one technique for measuring a variable can substitute another. In this article, we look at statistical measures of agreement for different types of data and discuss the differences between these and those for assessing correlation.
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109936/a-study-of-harmful-drug-drug-interactions-due-to-polypharmacy-in-hospitalized-patients-in-goa-medical-college
#17
Akshay Khandeparkar, Padmanabh V Rataboli
Introduction: Concomitant use of multiple drugs is often indicated to manage comorbid conditions and enhance efficacy. Such concomitant use of multiple drugs (five or more drugs) has been defined as "polypharmacy." Polypharmacy has been associated with adverse consequences such as greater healthcare costs, increased risk of adverse drug events, drug-drug interactions (DDIs), medication nonadherence, reduced functional capacity, and multiple geriatric syndromes. This study evaluated number of potential harmful DDIs due to polypharmacy...
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109935/striking-balance-between-expedited-review-and-expecting-efficacious-anticancer-drug-and-biologics-an-ongoing-challenge
#18
Krishnan Vengadaragava Chary, Anita Ramesh
Objective: The objective of this study is to assess the postmarketing status: Efficacy and safety drugs and biologics related with cancer approved under expedited review. Methods: This observational, analytical study was carried between January and April 2016 by the Department of Pharmacology and Medical Oncology, Saveetha Medical College. Drugs approved under expedited review, fast-track status and its association with anti-cancer effects, postmarketing efficacy and safety, propensity to induce the second tumor was noted...
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109934/do-clinical-trials-conducted-in-india-match-its-healthcare-needs-an-audit-of-the-clinical-trials-registry-of-india
#19
Mansi Chaturvedi, Nithya J Gogtay, Urmila M Thatte
Background: India continues to contribute disproportionately to the global burden of disease and public health research output from India is also known to be not commensurate with her healthcare needs. We carried out the present study to assess if clinical trials were in line with the health care needs of the country by auditing the clinical trials registry of India. Materials and Methods: All the clinical studies registered in CTRI between July 20, 2007 and December 31, 2015 were searched in the "Trial Search" section...
October 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29109933/a-study-comparing-trial-registry-entries-of-randomized-controlled-trials-with-publications-of-their-results-in-a-high-impact-factor-journal-the-journal-of-the-american-medical-association
#20
Poorwa Wandalkar, Prajakta Gandhe, Ashutosh Pai, Manasi Limaye, Shailesh Chauthankar, Nithya J Gogtay, Urmila M Thatte
Purpose: The International Committee of Medical Journal Editors mandates trial registration as a precondition for publication. Growing evidence indicates that information in registry may not correlate with eventual publication. The present study was carried out with the objective of comparing content of Randomized Controlled Trials (RCTs) published in one year in the Journal of the American Medical Association (JAMA), with the information contained in trial registries. Methods: All RCTs published in JAMA in 2013 were included...
October 2017: Perspectives in Clinical Research
journal
journal
43408
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"