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Journal of Laboratory Physicians

Preeti Chavan, Vivek Bhat, Ashwadeep Karmore, Rajani Mohite, Swati Waykar, Hemali Kadu
No abstract text is available yet for this article.
January 2017: Journal of Laboratory Physicians
Preeti Thakur, Charu Nayyar, Vibhor Tak, Karnika Saigal
No abstract text is available yet for this article.
January 2017: Journal of Laboratory Physicians
Tuhina Banerjee, Sourav Pal, Arghya Das
No abstract text is available yet for this article.
January 2017: Journal of Laboratory Physicians
Arulselvi Subramanian, Garima Aggarwal, Deepak Agarwal, Sanjeev Lalwani
Fibromuscular dysplasia (FMD) is a rare, segmental, nonatheromatous, and noninflammatory arterial disease of unknown etiology. It predominantly involves renal artery (60-75%) followed by extracranial part of the internal carotid artery and vertebral arteries (25-30%). The disease typically affects middle-aged women and involves intermediate-sized arteries throughout the body. There are rare case reports of extracranial FMD compounding a trauma case. A patient was brought to trauma center emergency with a history of fall from height...
January 2017: Journal of Laboratory Physicians
Shweta Raut, Swapna Kanade, Gita Nataraj, Preeti Mehta
Despite India achieving the goal of elimination of leprosy as a public health problem, leprosy is still being transmitted in India. However, due to decreased clinical suspicion of leprosy and atypical case presentations, such cases may be not be diagnosed. We present a case report of an unusual presentation of multibacillary leprosy which presented as nodular lesions. This case report indicates that atypical presentations of leprosy may be missed out by primary care physicians.
January 2017: Journal of Laboratory Physicians
Vrushali Patwardhan, Preena Bhalla, Deepti Rawat, Vijay Kumar Garg, Kabir Sardana, Sumit Sethi
OBJECTIVE: To compare laboratory tests that can simultaneously detect and type herpes simplex virus (HSV) directly from the genital ulcer specimens in clinically suspected cases of genital herpes. MATERIALS AND METHODS: A study was conducted over 10 months and 44 adult male and female patients clinically suspected with genital herpes were recruited. Genital ulcer swab specimens were subjected to glycoprotein-G gene-based conventional polymerase chain reaction (PCR) and commercially available direct fluorescent antibody (DFA) test and the results were compared...
January 2017: Journal of Laboratory Physicians
Syed Beenish Rufai, Sarman Singh, Amit Singh, Parveen Kumar, Jitendra Singh, Anand Vishal
BACKGROUND: Diagnosis of abdominal tuberculosis (TB) from ascitic fluid samples using routinely available diagnostic methods is challenging due to its paucibacillary nature. Although performance of Xpert MTB/RIF assay has been evaluated extensively on pulmonary samples, its performance on extrapulmonary samples is still under evaluation. OBJECTIVES: The objective of this study was to find out the performance of Xpert MTB/RIF on ascitic fluid samples obtained from suspected cases of abdominal TB...
January 2017: Journal of Laboratory Physicians
Hamed Aminiahidashti, Farzad Bozorgi, Seyed Jaber Mousavi, Omid Sedighi, Ali Morad Heidari Gorji, Hale Rashidian
AIM: This study was conducted to evaluate the validity of serum uric acid (UA) in prediction of mortality among patients in the emergency department. MATERIALS AND METHODS: This is a prospective cohort study which was conducted during 2014. In this study, 120 critically ill patients who required Intensive Care Unit care services were included. For evaluation of severity of the disease, mortality in emergency department score (MEDS) in the first 24 h of admission, the requirement of using mechanical ventilation, taking vasopressor during the hospitalization time and severity of the disease based on MEDS score were measured...
January 2017: Journal of Laboratory Physicians
Alagilawada S Shilpasree, Vidya S Patil, Vijayetha P Patil, Deepti G Ingleshwar
INTRODUCTION: Postprandial hyperglycemia is a major risk factor for the development of cardiovascular diseases (CVDs), and Most of the times it occurs in patients with normal glycemic control diagnosed by fasting blood glucose (FBG) and glycated hemoglobin levels. Urine albumin excretion (UAE) is an independent predictor of CVD risk. AIM: To estimate UAE in isolated postprandial hyperglycemia (IPPHG) patients and to assess the relationship of UAE with FBG and postprandial blood glucose (PPBG) levels...
January 2017: Journal of Laboratory Physicians
Vrishali Avinash Muley, Dnyaneshwari Purushottam Ghadage, Gauri Eknath Yadav, Arvind Vamanrao Bhore
BACKGROUND: Invasive pneumococcal infections often prove rapidly fatal, even where good medical treatment is readily available. In developed countries, up to 20% of people who contract pneumococcal meningitis die; however, in developing world, mortality is closer to 50%, even among hospitalized patients. The World Health Organization estimated 600,000-800,000 adult deaths each year from pneumococcal pneumonia, meningitis, and sepsis. AIMS: This study aims to estimate isolation rate of invasive pneumococcal infection in adults, to determine the antimicrobial susceptibility profile of Streptococcus pneumoniae isolates and to study the associated risk factors...
January 2017: Journal of Laboratory Physicians
Sabina Khan, Mukta Pujani, Sujata Jetley
BACKGROUND: Primary nasal tuberculosis (TB) is a rare form of TB even in areas with high TB incidence. It is timely diagnosis and proper management are often delayed due to its rarity and nonspecific clinical presentation. AIM: The aim of the study was to review histopathologically diagnosed cases of nasal TB over a period of 1 year and to describe its clinical presentation, diagnostic workup, the importance of histopathological diagnosis along with a brief review of the literature...
January 2017: Journal of Laboratory Physicians
Varun Goel, Dinesh Kumar, Raghavendra Lingaiah, Sarman Singh
INTRODUCTION: Occupational hazards such as accidental exposure to sharp, cuts, and splashes are common among health-care workers (HCWs). AIMS AND OBJECTIVES: To determine the occurrence of self-reported occupational exposures to these hazards and to know the prevalent practices following the exposure. The second aim was to know the baseline antibody levels against hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) immediately after these accidents...
January 2017: Journal of Laboratory Physicians
Swapna Muthusamy, Selvi Elangovan
INTRODUCTION: Women with high-risk sexual behavior accounts for more than half of the sexually transmitted infection (STI) clinic attendees. The prevalence of trichomoniasis is as low as 5% in the general population to as high as 60% in high-risk population. This infection can pave the way to the acquisition of human immunodeficiency virus and other STIs, vice versa and is even associated with cancer. OBJECTIVES: To identify, isolate and study the prevalence of Trichomonas vaginalis in genital specimens of female outpatients...
January 2017: Journal of Laboratory Physicians
Kamal Kachhawa, Poonam Kachhawa, Meena Varma, Rasmirekha Behera, Divya Agrawal, Sanjay Kumar
BACKGROUND: Storage of serum and other blood products is often necessary in laboratories because of technical issues or to preserve samples for subsequent research purposes. The aim of this study was to determine whether the stability of biochemical analytes is affected by storage conditions. MATERIALS AND METHODS: A total of 17 biochemical analytes in the sera of ten patients were examined following storage. Subsequent to determining the baseline measurements, the serum of each patient was aliquoted and stored at -20°C for 7, 15, and 30 days and then analyzed for stability...
January 2017: Journal of Laboratory Physicians
Kempula Geethamala, Venkataramappa Srinivasa Murthy, Bangalore Ramalingiah Vani, Madireddi Sudha Rao, Malugnalli Uddappa Thejaswini, Krishnarajapet Padmanabha Padmaja
INTRODUCTION: Breast carcinoma is the most common cancer among women in the urban Indian population. Conventionally, immunohistochemistry (IHC) is done to determine the hormone receptor status of the tumor. Immunocytochemistry (ICC) on fine-needle aspiration cytology (FNAC) was carried out to determine the same hormone receptor status of the tumor. OBJECTIVE: The study was undertaken to evaluate the diagnostic reliability of performing estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (Her2/neu) receptor status on FNAC by ICC and to compare the results with IHC...
January 2017: Journal of Laboratory Physicians
Sidra Asad, Imran Ahmed, Natasha Ali
BACKGROUND AND OBJECTIVE: With the advent of automated hematology analyzer, the use of traditional microscopy of blood film has become limited. The objective of our study was to determine the percentage of peripheral blood smear review in our institution in the era of automation and to identify reasons of manual review. MATERIALS AND METHODS: This was a prospective audit from January 1, 2015, to January 15, 2015. Consecutive complete blood count (CBC) samples and peripheral smear requests made up the sample size...
January 2017: Journal of Laboratory Physicians
Ruchita Tyagi, Arshdeep Kaur, Pavneet Kaur Selhi, Harpreet Kaur Puri, Neena Sood
Histoplasma capsulatum is no longer confined to certain geographic areas and should always be considered in the differential diagnosis of lymphadenopathy and organomegaly in HIV-positive patients. We present an unusual case of a 20-year-old immunocompromised male of African origin presenting with fever, jaundice, hepatosplenomegaly, and retroperitoneal and cervical lymphadenopathy. Fine needle aspiration (FNA) smears from the cervical lymph node revealed numerous yeast forms of histoplasma in macrophages. The patient succumbed to the fulminant infection...
July 2016: Journal of Laboratory Physicians
Navjot Kaur, Bal Chander, Harjit Kaur, Rashmi Kaul
Heterotopic pancreatic tissue in the gall bladder is an uncommon incidental finding in most cases. We hereby describe the case of a 45-year-old woman who presented with symptoms of acalculous cholecystitis. Pathological examination detected heterotopic pancreatic tissue, pseudopyloric metaplasia, and adenomyomatous hyperplasia in the gall bladder. This is a rare combination of three entities which is being reported for the first time. This case emphasizes that heterotopic pancreas might be the causative factor for cholecystitis...
July 2016: Journal of Laboratory Physicians
Biswajit Dey, Bhawana Badhe, Krishna Kumar Govindarajan, Ranjith Arumbakkam Ramesh
Xp11.2 translocation renal cell carcinomas (TRCCs) are a group of neoplasms with distinct clinical, histopathological appearance, immunohistochemical, and cytogenetic profile. We report a case of Xp11.2 translocation TRCC in an 11-year-old male diagnosed based on immunohistochemistry and fluorescence in situ hybridization.
July 2016: Journal of Laboratory Physicians
Jai Bhagwan Sharma
Female genital tuberculosis (FGTB) is an important cause of infertility in developing countries. Various type of TB salpingitis can be endosalpingitis, exosalpingitis, interstitial TB salpingitis, and salpingitis isthmica nodosa. The fallopian tubes are thickened enlarged and tortuous. Unilateral or bilateral hydrosalpinx or pyosalpinx may be formed. A new sign python sign is presented in which fallopian tube looks like a blue python on dye testing in FGTB.
July 2016: Journal of Laboratory Physicians
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