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Journal of Ayurveda and Integrative Medicine

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https://www.readbyqxmd.com/read/28917550/antidiabetic-potential-of-methanolic-and-flavonoid-rich-leaf-extracts-of-synsepalum-dulcificum-in-type-2-diabetic-rats
#1
Olabisi T Obafemi, Clement A Akinmoladun, Tolulope M Olaleye, Stephen O Agboade, Amos A Onasanya
BACKGROUND: Synsepalum dulcificum is a plant indigenous to West Africa. The fruit is used to modify taste of foods to sweetness. OBJECTIVES: This study aims to investigate the antidiabetic potentials of both methanolic and flavonoid-rich leaf extracts of S. dulcificum (MSD and FSD respectively) in type 2 diabetic Wistar albino rats. MATERIALS AND METHODS: Sixty three rats were randomly distributed into nine groups of seven animals each with group 1 serving as the normal control...
September 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28869083/antifungal-effect-of-cow-s-urine-distillate-on-candida-species
#2
J M Hoh, B Dhanashree
BACKGROUND: Increase in resistance of Candida species, to routinely used antifungal agents has necessitated the quest for new drugs. Few studies have revealed that cow's urine can suppress the growth of pathogenic fungi. However there is no published report on antifungal effects of cow's urine on clinical Candida isolates. OBJECTIVE: The present study aims at exploring the antifungal potential of cow's urine on clinical isolates of Candida species. MATERIAL & METHODS: In this in-vitro experimental study four standard strains and 37 clinical isolates of Candida species were tested for their susceptibility to amphotericin B, fluconazole and voriconazole, by disk diffusion method...
August 30, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28865750/evaluation-of-kunapa-jala-and-pancha-gavya-on-plant-quality-physiology-biochemistry-yield-and-growth-attributes-a-case-study-of-withania-somnifera-dun
#3
Gireesh M Ankad, Jagadishchandra Hiremath, R T Patil, H J Pramod, Harsha V Hegde
BACKGROUND: 'Vrikshayurveda', an ancient science of plant life described by Surapala, has clearly outlined a systematized agricultural practice that insisted on the use of Kunapa jala (KJ) and Pancha gavya (PG) to enhance the yield and quality of plants. OBJECTIVE: An experiment was conducted to evaluate the effect of KJ and PG on growth, physiological, biochemical, quality attributes and yield of Withania somnifera Dun. MATERIALS AND METHODS: The effect of KJ and PG was evaluated in comparison with control, organic (farmyard manure and humic acid) and inorganic (NPK) fertilizer at 60, 90, 120 and 150 days after sowing (DAS)...
August 30, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28869082/development-of-botanicals-to-combat-antibiotic-resistance
#4
REVIEW
Pooja D Gupta, Tannaz J Birdi
The discovery of antibiotics in the previous century lead to reduction in mortality and morbidity due to infectious diseases but their inappropriate and irrational use has resulted in emergence of resistant microbial populations. Alteration of target sites, active efflux of drugs and enzymatic degradations are the strategies employed by the pathogenic bacteria to develop intrinsic resistance to antibiotics. This has led to an increased interest in medicinal plants since 25-50% of current pharmaceuticals are plant derived...
August 28, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28826837/urticarial-rashes-following-guggulu-intake-a-case-report
#5
Sanjeev Rastogi
Ayurvedic drugs are anecdotally considered safe and are sparingly reported for adversity upon their usage. Reporting adversity however helps understanding the drug pharmacodynamics in a given case and prompts for its safe future application. The patient here has reported urticarial rashes upon use of an Ayurvedic guggulu preparation. The observations were repeated upon the repeated use of the drug. These symptoms were compelling enough to look for a rescue medicine and to withdraw the primary medicine. Guggulu is known for its gastrointestinal and hepatic adversities in some cases...
August 18, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28823790/evolving-herbal-formulations-in-management-of-dengue-fever
#6
Pawan Kumar Singh, Pooja Rawat
Dengue is endemic in more than 100 countries and it is estimated that annually above 390 million infections occur globally. During the period between 1996-2015, a massive increase of more than 500 per cent has been recorded in number of dengue cases reported in India. Till date, there are no specific globally accepted treatments for dengue fever in any system of medicine. Dengue does not cause very high mortality if properly handled and is currently being managed by clinicians through various adjuvant and alternative therapeutic options...
August 17, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28822619/experiential-documentation-of-trimad-for-its-anti-obesity-potential-a%C3%A2-survey-of-ayurvedic-physicians-from-pune-city
#7
Megha Salunke, Manasi Deshpande, Supriya Bhalerao
BACKGROUND: Trimad is an Ayurvedic polyherbal formulation consisting of tubers of Mustaka (Cyperus rotundus), fruits of Vidanga (Embelia ribes) and roots of Chitraka (Plumbago zeylanica). It is recommended in Ayurveda for the management of obesity. However, there is no documented evidence about its safety and efficacy. Hence, as a first step, we carried out a survey to find out its usage by Ayurvedic physicians and their personal clinical experiences while using the formulation. METHODOLOGY: A questionnaire was designed which included questions regarding the usage, dosage, formulation, safety and tolerability of Trimad...
August 16, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28757226/preparation-and-physicochemical-characterization-of-ingredients-of-indian-traditional-medicine-mahamrutyunjaya-rasa
#8
Pallavi Rai, Sadhana J Rajput
BACKGROUND: Mahamrutyunjaya rasa is an ayurvedic formulation used in the treatment of cardiac disorders. It contains the purified roots of Visa (Aconitum ferox), Brihati (Solanum indicum), fruits of Pippali Kana (Piper longum), Marica (Piper nigrum), Gandhaka (Sulfur), Hingula (Cinnabar) and Tankana (Sodium metaborate) as per Bhaishajya Ratnavali. The purification (shodhana) process changes the physiochemical properties of the raw materials which need to be studied and understood. OBJECTIVE: The present work aims to perform a comprehensive physicochemical characterization of raw materials, intermediates and the final product obtained during purification, using modern analytical techniques...
July 27, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28757225/clinical-evaluation-of-vatariguggulu-maharasnadikwatha-and-narayan-taila-in-the-management-of-osteoarthritis-knee
#9
Anil Mangal, M N Shubhasree, Pramila Devi, A D Jadhav, Sai A Prasad, Kisore Kumar, Sarada Otta, K S Dhiman
BACKGROUND: In present era, pharmacological, bio-chemical and surgical interventions are not success remedy for Osteoarthritis (OA). Ayurveda and other complementary medicine have medication for OA. OBJECTIVES: The main aim of the study was to assess the efficacy and safety of therapeutic combination of Vatari guggulu along with Maharasnadi kwatha and Narayan taila with gentle massage for 15 min daily up to 12 weeks on affected knee joint pain assessed on Visual analogue scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)...
July 27, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28693955/adaptogenic-potential-of-oxitard-in-experimental-chronic-stress-and-chronic-unpredictable-stress-induced-dysfunctional-homeostasis-in-rodents
#10
Brajnandan Kishor, Pooja Rai, Rakesh Bharatia, Sanjay Kumar, Sujeet Kumar Gupta, Anshuman Sinha
BACKGROUND: Oxitard, a polyherbal formulation comprising the extracts of Withania somnifera, Mangifera indica, Glycyrrhiza glabra, Daucus carota, Vitis vinifera, powders of Syzygium aromaticum, Yashada bhasma and Emblica officinalis; and oils of Triticum sativum. OBJECTIVE: Current study deals with the assessment of Oxitard (a marketed polyherbal formulation) for its adaptogenic potential in chronic unpredictable stress (CUS) and chronic stress (CS) induced dysfunctional homeostasis in rodents...
July 7, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28690055/antitumor-effect-of-ferula-assa-foetida-oleo-gum-resin-against-breast-cancer-induced-by-4t1-cells-in-balb-c-mice
#11
Seyyed Majid Bagheri, Amir Abdian-Asl, Mahin Taheri Moghadam, Maryam Yadegari, Aghdas Mirjalili, Fatemeh Zare-Mohazabieh, Haniyeh Momeni
BACKGROUND: Ferula assa foetida commonly consumed as a healthy beverage has been demonstrated to have various biological activities, including antioxidation, anti-obesity and anti-cancer. OBJECTIVE: Our study aims to investigate the antitumor effect of asafoetida in vivo using mouse mammary carcinoma 4T1 cells. MATERIALS AND METHODS: In the study, female BALB/c mice were divided into two groups (n = 6), which were control (untreated) and other group of mice with breast cancer treated with 100 mg/kg of asafoetida, respectively, by oral gavage...
July 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28688542/evaluation-of-apoptotic-activity-of-withania-coagulans-methanolic-extract-against-human-breast-cancer-and-vero-cell-lines
#12
Rumana Ahmad, Afreen Fatima, A N Srivastava, Mohsin Ali Khan
BACKGROUND: The genus Withania (Family: Solanaceae) holds an important position in Ayurveda, the Indian traditional system of medicine. Withania somnifera Dunal and Withania coagulans Dunal have been documented in folklore as panaceas for various ailments since time immemorial. W. coagulans (WC), commonly called as Indian cheese maker is used for fermenting milk for cheese production in various parts of India. OBJECTIVES: In the study, in vitro cytotoxicity of methanolic extract of dried fruits (berries) of WC was evaluated in a dose dependent manner using trypan blue dye exclusion method against human breast cancer cell line MDA-MB-231 and normal kidney epithelial cell line Vero in the range 20-200 μg/ml...
July 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28669703/design-and-development-of-unani-anti-inflammatory-cream
#13
Sana Fatima, Roohi Zaman, Nafis Haider, Shariq Shamsi, Anzar Alam
Inflammation is the symptom of many diseases like rheumatoid arthritis and osteoarthritis. Many side effects are associated with the Non-Steroidal Anti-inflammatory Drugs (NSAIDs) used as conventional treatment for these conditions. In Unani, there are large number of single and compound drugs for inflammatory conditions. One dosage form of Unani system of medicine is named as Zimad in which paste is formed by mixing powder in oil, water, herbal extract. Zimadat is prepared just before application and used in many disease conditions as resolving, styptic, astringent, and antiseptic...
June 29, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28668259/ayurvedic-anti-diabetic-formulation-lodhrasavam-inhibits-alpha-amylase-alpha-glucosidase-and-suppresses-adipogenic-activity-in%C3%A2-vitro
#14
Megha Abhijit Butala, Subrahmanya Kumar Kukkupuni, Chethala N Vishnuprasad
BACKGROUND: The patho-physiological cross-talk between diabetes and obesity is well established. However, the choices of drugs suitable for combined treatment of diabetes and obesity are limited. Integration of complementary and alternative medicines (CAMs), like Ayurveda, with modern medicine would be a promising strategy to fill this gap. The diagnostic principles of Ayurveda define obesity as one of the predisposing factors of Madhumeha (correlated as diabetes) and recommends specific formulations for managing obese-diabetes...
June 28, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28648875/shotha-and-the-unified-theory-of-inflammatory-diseases-2017
#15
V Mishra, T Rajavashisth
No abstract text is available yet for this article.
June 22, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28610894/mangiferin-protects-rat-myocardial-tissue-against-cyclophosphamide-induced-cardiotoxicity
#16
Laxit Bhatt, Binu Sebastian, Viraj Joshi
BACKGROUND: Mangiferin is a highly potent antioxidant present in mango leaves which is utilized for therapeutic purposes. OBJECTIVE: The present study was undertaken to evaluate the cardioprotective effect of mangiferin against cyclophosphamide induced cardiotoxicity. MATERIALS AND METHODS: Rats were treated with 100 mg/kg of mangiferin in alone and interactive groups for 10 days. Apart from normal and mangiferin control groups, all the groups were subjected to cyclophosphamide (200 mg/kg, i...
April 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28602428/influence-of-amalaki-rasayana-on-telomerase-activity-and-telomere-length-in-human-blood-mononuclear-cells
#17
Kanive P Guruprasad, Sweta Dash, Marigowda B Shivakumar, Pavithra R Shetty, Kothanahalli S Raghu, Bhanuvalli R Shamprasad, Vishwanatha Udupi, Raviraj V Acharya, Prasanna B Vidya, Jayakrishna Nayak, Anandan E Mana, Rajesh Moni, Muraleedharan T Sankaran, Kapaettu Satyamoorthy
BACKGROUND: Indian traditional medicine practices use defined rasayana preparations to improve the quality of life in aged individuals. Amalaki Rasayana is one such rasayana prepared from the fruits of Phyllanthus emblica and is popularly used to prevent or treat various age related health conditions. Telomerase activity in the cells maintains telomere length and is implicated in ageing and various diseases wherein the shortening of telomere during ageing is controlled chiefly by the telomerase activity...
April 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28601355/yogic-breathing-practices-improve-lung-functions-of-competitive-young-swimmers
#18
Chirag Sunil Hakked, Ragavendrasamy Balakrishnan, Manjunath Nandi Krishnamurthy
BACKGROUND: Resistive breathing practices are known to improve endurance and performance in competitive swimmers. However, the effect of Pranayama or Yogic Breathing Practices (YBP) in improving respiratory endurance and performance of competitive swimmers remains un-investigated. OBJECTIVES: To study effects of yogic breathing practices on lung functions of swimmers. MATERIAL AND METHODS: Twenty seven national and international competitive swimmers of the age range 13-20 years, with 8...
April 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28601354/studies-on-wound-healing-potential-of-polyherbal-formulation-using-in%C3%A2-vitro-and-in%C3%A2-vivo-assays
#19
Yogesh P Talekar, Kishori G Apte, Shubhangi V Paygude, Prasad R Tondare, Pradeep B Parab
BACKGROUND: The use of herbal plant extracts in wound healing is known through decades, but it is necessary to provide scientific data through reverse pharmacology. OBJECTIVE: The aim of the present study is to find the mechanism behind the healing of wounds using in vitro and in vivo assays. MATERIAL AND METHODS: The study was designed to determine proliferation and mobilization of fibroblast and keratinocytes at the site of injury, angiogenesis at the site of healing and reduction in oxidative stress while healing...
April 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28600167/in-vivo-study-of-tissue-reaction-to-crotalaria-pallida-and-sansevieria-roxburghiana-fibers
#20
Sahana Kamath, Muralidhara Sharma, B Ravishankar, Ravi Mundugaru
BACKGROUND: A suture material producing least tissue reaction is considered as ideal. Other characteristics like tensile strength, capacity to sustain sterilization process enhance its acceptability. In the present situation there is a need to reascertain the relevance and utility of these materials. Among the suture materials mentioned by Sushrutacharya, Moorva (Sansevieria roxburghiana) and Shana (Crotalaria pallida) have been showed insignificant tissue reaction in operated cases of inguinal hernia...
April 2017: Journal of Ayurveda and Integrative Medicine
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