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Journal of Ayurveda and Integrative Medicine

B Ganga, Abdul Wadud, Nasreen Jahan, Shaikh Ajij Ahmed Makbul
BACKGROUND: Habbe Gule Aakh is extensively used in Unani medicine for anti-inflammatory and analgesic activity. OBJECTIVE: To evaluate anti-inflammatory and analgesic effects of Habbe Gule Aakh on Wistar rats and Swiss mice of either sex. MATERIALS AND METHODS: The study was carried out in Wistar rats for anti-inflammatory activity while Swiss mice were used for analgesic activity. In both the tests animals were divided into five groups of six animals each which served as control, standard and test groups A, B and C...
November 7, 2018: Journal of Ayurveda and Integrative Medicine
Deep Narayan Pandey, Neha Pandey Prakash
There is a fundamental principle in Ayurveda, known as the principle of Samanya (similarity) and Vishesha (difference). While the principle was essentially propounded in the context of yuktivyapashraya (rational medicine) in Ayurveda, here we would like to argue that it has universal applicability in Ayurveda and beyond, across systems and domains of knowledge, including science, technology and humanities, as well as scientific, experiential and traditional knowledge systems. Taking examples of some of the most well-known problems of ecology, economy and society, we demonstrated the universal significance of the principle of Samanya and Vishesha...
November 3, 2018: Journal of Ayurveda and Integrative Medicine
Preena Sidhu, Swapnil Shankargouda, Avita Rath, Priyadarshini Hesarghatta Ramamurthy, Bennete Fernandes, Ashish Kumar Singh
Oral health influences general well-being and quality of life. Oral diseases can be debilitating and are a major heath concern worldwide. Medicinal plants have been used for thousands of years for treating human diseases. Considering the emergence of multi-drug resistant pathogens and financial difficulties in developing countries, there is an urgent need for developing new antimicrobial compounds which are safe, efficient and cost effective. Liquorice also known as yashtimadhu, sweetwood or mulhatti is one such herbal remedy which has shown to have immense potential in treatment of orofacial diseases...
October 31, 2018: Journal of Ayurveda and Integrative Medicine
Yogesh L Tamhankar, Archana P Gharote
BACKGROUND: Rasashastra needs to be upgraded using the technological advances, with regards to drug processing, development and therapeutics. The potential of Rasaaushadhis need to be explored by subjecting them against newer life threatening diseases like cancer where contemporary medicine has limitations. Abhrak Bhasma, one of the drugs of Rasashastra, has some peculiar attributes. According to classical Rasashastra texts, Shataputi Abhrak Bhasma is regarded as a Rasayan, whose efficacy is in direct proportion to the number of Putas...
October 31, 2018: Journal of Ayurveda and Integrative Medicine
Karthikeyan Ramalingam, Bennett T Amaechi
BACKGROUND: Dental caries is a biofilm-related infectious disease with a multifactorial etiology, over five billion inhabitants have affected worldwide due to this disease. OBJECTIVE: Antimicrobial efficacy of a mixed herbal powder extract (MHPE) against cariogenic microorganisms was investigated. MATERIALS AND METHODS: MIC, MBC, kinetics of killing, biofilm disruption and anticaries effect of MHPE were determined. For biofilm disruption, biofilms of Streptococcus mutans, Lactobacillus casei, Actinomyces viscosus and Candida albicans were treated with MHPE for 30 min and attached cells were quantified after staining...
October 30, 2018: Journal of Ayurveda and Integrative Medicine
Victor Kuete, Leonidah K Omosa, Jacob O Midiwo, Oğuzhan Karaosmanoğlu, Hülya Sivas
BACKGROUND: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. OBJECTIVES: The present study was designed to evaluate the cytotoxicity of 11 naturally occurring compounds including six phenolics amongst them were 4 chalcones and 2 flavanones as well as 5 terpenoids (3 clerodane and 2 trachylobane diterpenoids) against 6 human carcinoma cell lines and normal CRL2120 fibroblasts. MATERIALS AND METHODS: The neutral red uptake (NR) assay was used to evaluate the cytotoxicity of the compounds, whilst caspase-Glo assay was used to detect caspase activation...
October 30, 2018: Journal of Ayurveda and Integrative Medicine
Paul J Mills, Christine Tara Peterson, Kathleen L Wilson, Meredith A Pung, Sheila Patel, Lizabeth Weiss, Suhas G Kshirsagar, Rudolph E Tanzi, Deepak Chopra
BACKGROUND: According to Ayurveda, the traditional medical system of India, doshas are a combination of characteristics based on a five-element philosophy that drive our mental and physical tendencies. When the doshas, or functional principles, are out of balance in quality or quantity, wellbeing is adversely affected and symptoms manifest. OBJECTIVES: This study examined relationships among imbalances in the doshas (termed Vikruti) reported via questionnaire and Western measures of psychological states...
October 29, 2018: Journal of Ayurveda and Integrative Medicine
V J Shine, G I Anuja, S R Suja, Gopan Raj, P G Latha
BACKGROUND: Cyclea peltata is one of the herbs mentioned in ancient scriptures of Ayurveda and is used in different types of Ayurvedic gritham preparations. Moreover, in traditional/tribal medicine C. peltata is used as digestive, anti-inflammatory, diuretic and to treat jaundice, digestive disorders, etc. OBJECTIVE: Activity guided fractionation of C. peltata and in correlation with the levels of bioactive compound tetrandrine. MATERIALS AND METHODS: Preliminary phytochemical screening, estimation of total alkaloid content, preparation of different extracts of C...
October 23, 2018: Journal of Ayurveda and Integrative Medicine
Deepthi Rapaka, Veera Raghavulu Bitra, T Chandi Vishala, Annapurna Akula
BACKGROUND: Aluminum a known neuro and cholinotoxin has been implicated in the pathogenesis of Alzheimer's disease. Its exposure is associated with impairment of the memory and cognition. OBJECTIVE: The present study was undertaken to evaluate the anti-Alzheimer's activity of Vitis vinifera in aluminum induced Alzheimer's disease. MATERIALS AND METHODS: In this study, we investigated the behavioral and biochemical effects of aluminum in Sprague-Dawley rats...
October 15, 2018: Journal of Ayurveda and Integrative Medicine
Alok K Hazra, Banti Chakraborty, Achintya Mitra, Tapas Kumar Sur
BACKGROUND: Trikatu, Sitopaladi, Hingavastaka, Avipattikara, Sringyadi and Talisadya are very popular Ayurvedic (churna) medicines practiced in India; however, unfortunately, they possess several quality control issues. OBJECTIVE: The aim of this study was to find out a simple, accurate and sensitive HPTLC method for the detection and quantification of marker molecule, piperine (alkaloid) on these Ayurvedic formulations for standardization. MATERIALS AND METHODS: Methanolic extraction (reflux) was performed from the above six churnas as well as three single ingredients Piper longum (pipul), Piper nigrum (marich) and Piper chaba (chai)...
October 11, 2018: Journal of Ayurveda and Integrative Medicine
Rathinasamy Baskaran, Lohanathan Bharathi Priya, V Sathish Kumar, Viswanadha Vijaya Padma
BACKGROUND: Cadmium (Cd) pollution is of serious concern due to its toxic effects in both humans and animals. The study investigates the protective effect of Tinospora cordifolia stem methanolic extract (TCME) on Cd induced hepatotoxicity. OBJECTIVE: The aim of the study was to explore the hepatoprotective effects of T. cordifolia extract. MATERIALS AND METHODS: Rats were administered orally with Cd (5 mg/kg) and TCME (100 mg/kg) for 28 days...
October 10, 2018: Journal of Ayurveda and Integrative Medicine
Venkatachalam Duraisamy, Pruthu Thekkur, Marie Gilbert Majella, Manikandan Srinivasan, Ganesh Kumar Saya, Palanivel Chinnakali
BACKGROUND: Siddha system is a complementary system of medicine popular in South India. Information on common morbidities for which people seek care in Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy (AYUSH) systems and especially in Siddha hospitals is very limited. This knowledge will help in prioritizing diseases and developing standard treatment guidelines. OBJECTIVES: The present study was designed with the aim to describe the morbidity profile of the adult patients attending Siddha Out Patient Department (OPD) at Government Hospitals in Erode district of Tamil Nadu...
October 8, 2018: Journal of Ayurveda and Integrative Medicine
Sane Rohit, Mandole Rahul
BACKGROUND: Heart failure reversal therapy (HFRT) is designed to enhance cardiorespiratory fitness of chronic heart failure (CHF) patients. OBJECTIVES: The present study was designed to evaluate efficacy of HFRT that uses herbal procedure (panchakarma) and allied therapies, in CHF patients with low ejection fraction. METHODS: This efficacy study was conducted in CHF patients (aged: 25-65 years, ejection fraction (EF) 10-30%) wherein HFRT (60-75 min) consisting of snehana (external oleation), swedana (passive heat therapy), hrudaydhara (concoction dripping treatment) and basti (enema) was administered twice daily for 7 days...
October 1, 2018: Journal of Ayurveda and Integrative Medicine
Monis Mohd, G Sofi, Nasreen Jahan, Zarreen Baig
Murakkab drugs of Unani medicine have remained an important aspect of disease treatment since antiquity. Physicians prepared different formulations for various diseases. The formulations thus prepared have always been of two categories. One category of Murakkab drugs was those which were formulated empirically and remained in use without conceptual framework behind these formulations. These formulations were categorized as Mujarrab (tested) formulations. The other category of formulations was prepared in consideration with theoretical framework of Mizaj (temperament) and Usoole ilaj (treatment strategy) and then tested by physicians...
August 16, 2018: Journal of Ayurveda and Integrative Medicine
Anand Kumar Keshari, Ragini Srivastava, Payal Singh, Virendra Bahadur Yadav, Gopal Nath
BACKGROUND: Silver nanoparticles are toxic to bacteria and have widespread application in different research areas. OBJECTIVE: The aim of this study was to synthesize silver nanoparticles using an aqueous leaf extract of Cestrum nocturnum and to test its antioxidant and antibacterial activities. MATERIALS AND METHODS: The silver nanoparticles were synthesized by addition of 20 ml extract (8% w/v) with 180 ml silver nitrate solution (1 mM)...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
Rupinder Kaur, Sukhbir Kaur
BACKGROUND: The available drugs for treating visceral leishmaniasis are limited. Moreover, the disease is associated with suppression of immune function. Therefore, therapies with effective immunomodulatory agents are needed which can decrease parasitic burden and enhance adaptive immunity. OBJECTIVES: The present study was planned to evaluate the antileishmanial efficacy of crude ethanolic extract of roots of Chlorophytum borivilianum (CBREE) against murine visceral leishmaniasis through immunomodulation...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
A Vysakh, Kuriakose Jayesh, Lal Raisa Helen, Mathew Jyothis, M S Latha
BACKGROUND: The plant Rotula aquatica Lour. was traditionally well known due to its large number of pharmacological action and medicinal uses. The plant is a necessary component of many Ayurvedic drug preparations since historical times. It is widely used as a crucial ancient drug for kidney and bladder stones. OBJECTIVES: The main objective of the study was to evaluate the acute toxicity and anti inflammatory efficacy of methanolic extract of R.aquatica Lour. in in vivo models...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
Jayaraj Krupa, Jeyalatchagan Sureshkumar, Rajendran Silambarasan, Kanagaraj Priyadarshini, Muniappan Ayyanar
BACKGROUND: Ethnobotanical studies are recognized as effective methods of finding locally important plants for discovery of crude drugs. Siddha medicinal system is prevailed in south Indian states principally in Tamil Nadu and gaining recognition as alternative medicine among the indigenous communities for their primary healthcare needs. OBJECTIVES: The study was aimed to explore and document folk medicinal plant knowledge among the local people in Puliyankudi village of Thiruvarur District, Tamil Nadu, India...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
Neelam Soni, Vinay Kumar Singh, D K Singh
BACKGROUND: Fasciolosis is a water-borne disease with gastropods snail (Lymnaea acuminata) act as key-link is still burden for mankind especially in developing countries. Snail control is one of the important tools to trim down the frequency of fasciolosis. OBJECTIVE: To evaluate the toxic effect and inhibitory potential of plant Tamarindus indica and their active constituent on the key enzyme of nervous tissue of snail L. acuminata. METHOD: The present study deals with the chromatographic isolation and identification of molluscicidal component from Tamarindus indica bark and its effects on enzymes activities of vector snail L...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
Hnin Ei Thu, Zahid Hussain, Isa Naina Mohamed, Ahmad Nazrun Shuid
BACKGROUND: Eurycoma longifolia (E. longifolia) has gained remarkable recognition due to its promising efficacy of stimulating bone formation in androgen-deficient osteoporosis. Numerous in vivo studies have explored the effects of E. longifolia on osteoporosis; however, the in vitro cellular mechanism was not discovered yet. OBJECTIVES: The present study was aimed to investigate the effect of E. longifolia on the proliferation, differentiation and maturation of osteoclasts and the translational mechanism of inhibition of osteoclastogenesis using RAW 264...
August 14, 2018: Journal of Ayurveda and Integrative Medicine
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