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Journal of Ayurveda and Integrative Medicine

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https://www.readbyqxmd.com/read/29146110/exploring-molecular-mechanism-of-bone-forming-capacity-of-eurycoma-longifolia-evidence-of-enhanced-expression-of-bone-related-biomarkers
#1
Hnin Ei Thu, Isa Naina Mohamed, Zahid Hussain, Ahmad Nazrun Shuid
BACKGROUND: Among the numerous well-documented medicinal herbs, Eurycoma longifolia (EL) has gained remarkable recognition due to its promising efficacy of stimulating bone formation in androgen-deficient osteoporosis. Though numerous animal studies have explored the bone-forming capacity of EL, the exact mechanism was yet to be explored. OBJECTIVES: The present study was aimed to investigate the mechanism of bone-forming capacity of EL using MC3T3-E1 as an in vitro osteoblastic model...
November 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29137853/antidiabetic-antihyperlipidemic-activities-and-herb-drug-interaction-of-a-polyherbal-formulation-in-streptozotocin
#2
Vishnu P Choudhari, Ketkee P Gore, Anil T Pawar
BACKGROUND: Ojamin (OJ), a polyherbal antidiabetic formulation, is extensively used as a food supplement to control diabetes alone or along with synthetic antidiabetic agents. However, it's phytochemical and pharmacological investigations are lacking. OBJECTIVE: The present study was undertaken to study antidiabetic and antihyperlipidemic potentials of OJ and its interaction with Metformin in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: Diabetes was induced in Wistar rats by single intraperitoneal (i...
November 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29133027/nutrient-analysis-of-kunapa-jala-and-pancha-gavya-and-their-evaluation-on-germination-of-ashwagandha-withania-somnifera-dunal-and-kalamegha-andrographis-paniculata-nees-seeds-a-comparative-study
#3
Gireesh M Ankad, Jagadishchandra Hiremath, R T Patil, H J Pramod, Harsha V Hegde
BACKGROUND: Vrikshayurveda, an ancient science of plant life described by Surapala, deals with healthy growth and productivity of plants, which has clearly outlined a systematized agricultural practice that insisted the use of Kunapa jala (KJ) and Pancha gavya (PG). OBJECTIVE: An experiment was conducted to validate KJ and PG by nutrient analysis and their effect on the germination parameters of Ashwagandha and Kalamegha seeds in comparison with other treatment groups...
November 10, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29122455/looking-at-prescription-quality-in-ayurveda-developing-validating-and-pilot-testing-a-prescription-quality-index-for-ayurveda
#4
Sanjeev Rastogi
BACKGROUND: Prescription quality can be a direct predictor of the net outcome of a health care delivery effort. Quality of prescription may be considered as a cumulative matrix of multiple components of a prescription on the basis of their relative importance. Prescription quality index is a recognized tool in clinical medicine for multiple purposes including the prediction of health care intervention outcome. OBJECTIVES: Considering the importance of prescription quality among every system of medicine, an attempt was made to design a prescription quality index for Ayurveda...
November 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29122454/ayurveda-formulations-a-roadmap-to-address-the-safety-concerns
#5
Kishor Patwardhan, Jigyasa Pathak, Rabinarayan Acharya
It is a matter of serious concern that the number of case reports pointing at a possible association between the clinical toxicity and the use of Ayurveda formulations is increasing significantly over the years in scientific medical literature. Though most of these cases are connected with the presence of heavy metals such as lead, mercury and arsenic in these formulations, there are also reports suggesting toxicity due to the presence of toxic chemicals of herbal origin. In the year 2008, the Government of India took an initiative of establishing the National Pharmacovigilance Programme for Ayurveda, Siddha and Unani drugs in a structured way...
November 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29122453/action-research-on-education-in-ayurveda
#6
LETTER
Sanchit Misra
No abstract text is available yet for this article.
November 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29108946/nuclear-ribosomal-dna-its-region-based-molecular-marker-to-distinguish-the-medicinal-plant-gmelina-arborea-roxb-ex-sm-from-its-substitutes-and-adulterants
#7
Jaganathan Manokar, Subramani Paranthaman Balasubramani, Padma Venkatasubramanian
Roots of Gmelina arborea (Gambhari) is a medicinally important raw drug traded in India. However, Gmelinaasiatica and Mallotus nudiflorus are also found in the raw drug markets as Gambhari. The current study aims to identify molecular markers based on the nuclear ribosomal DNA - ITS1 region to distinguish the authentic species from substitute/adulterants. The nuclear ribosomal internal transcribed spacer 1 (ITS1) was amplified to identify species-specific markers using universal primers. Based on the sequence of the ITS region, specific primers were designed for G...
November 3, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29108945/assessing-the-ayurvedic-prescribing-trends-on-the-basis-of-who-drug-use-indicators
#8
Sanjeev Rastogi
BACKGROUND: Ayurvedic prescriptions are often challenged for their rationality. Excessive use of proprietary medicines, rasa preparations, and samshodhana without any justification and deliverable benefits outweighing the other forms of safer, cheaper and less time consuming therapies is putting the Ayurvedic prescribing trends into question. In Ayurvedic practice, prescriptions are often individualized with substantial variability between the choices of drugs. Although being welcomed as an advanced approach of prescription writing by making it tailor made, this method also allows for lapses to creep in thus making it necessary to check common trends of prescribing in Ayurveda and to see whether it raises any caution...
November 3, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29103851/interaction-of-p-synephrine-on-the-pharmacodynamics-and-pharmacokinetics-of-gliclazide-in-animal-models
#9
Leela Krishna Vatsavai, Eswar Kumar Kilari
BACKGROUND: Type 2 diabetes is frequently seen in patients suffering from obesity. p-Synephrine and gliclazide are widely used medicines for the treatment of obesity and diabetes, respectively. Based on the relationship between obesity and diabetes, the present study was undertaken to determine the potential for herb-drug interactions between p-synephrine and gliclazide. METHODS: Influence of p-synephrine on the activity of gliclazide was determined by conducting single and multiple dose interaction studies in animal models...
November 3, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29103852/significance-of-arterial-stiffness-in-tridosha-analysis-a-pilot-study
#10
P Venkata Giri Kumar, Sudheer Deshpande, Aniruddha Joshi, Pooja More, H R Nagendra
BACKGROUND: The variations in Tridoshas are the basis for disease diagnosis and treatment in Ayurveda. The doshas are assessed by sensing the pulse manually with fingers which depends on skill of the physician. There is a need to measure doshas using instruments and study them objectively. OBJECTIVE: Arterial stiffness is well established pulse parameter in modern medicine and is closely associated to kathinya in the context of Ayurveda. The aim of our study was to measure arterial stiffness using Nadi Tarangini, a pulse acquisition system, and investigate the significant variations of stiffness across Tridosha locations...
November 2, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29102462/altitudinal-variation-of-berberine-total-phenolics-and-flavonoid-content-in-thalictrum-foliolosum-and-their-correlation-with-antimicrobial-and-antioxidant-activities
#11
Garima Pandey, Sayyada Khatoon, M M Pandey, A K S Rawat
BACKGROUND: The quality of herbal medicine is determined by its secondary metabolites, which may vary according to growth, season and altitude etc. OBJECTIVE: We studied the variation in phytochemistry and biological activities of Thalictrum foliolosum (TF) roots collected from four sites at different altitudes. MATERIAL AND METHODS: The berberine content in different extracts of T. foliolosum roots collected from various altitudes was estimated using HPTLC...
November 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29102461/effect-of-swarna-jibanti-coelogyne-cristata-lindley-in-alleviation-of-chronic-fatigue-syndrome-in-aged-wistar-rats
#12
Achintya Mitra, Tapas Kumar Sur, Sachhidananda Upadhyay, Dipankar Bhattacharyya, Jayram Hazra
BACKGROUND: Swarna Jibanti scientifically known as Coelogyne cristata Lindley (Orchidaceae), an orchid mentioned in Ayurvedic medicine is used to promote healthy life span. OBJECTIVE: The present work was planned to study the efficacy of hydro-alcoholic extract of pseudobulbs of C.cristata (CCE) to assess its role on chronic fatigue syndrome (CFS) induced behavioural and biochemical changes in aged Wistar rats compared to Panax ginseng (PG), a prototype anti-stress agent...
November 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29089187/reliability-of-self-reported-constitutional-questionnaires-in-ayurveda-diagnosis
#13
Corina Dunlap, Douglas Hanes, Charles Elder, Carolyn Nygaard, Heather Zwickey
BACKGROUND: Ayurveda is one of the most ancient and widely practiced forms of medicine today, along with Traditional Chinese Medicine. It consists of determining an individual's constitution or Prakriti and current imbalance(s) through the use of multimodal approaches. Ayurveda practitioners may choose to include either a self-reported or structured interview constitutional questionnaire as part of the Prakriti assessment. Currently, there is no standardized or validated self-reported constitutional questionnaire tool employed by Ayurveda physicians or western Ayurveda educational institutions...
October 28, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29089186/how-to-plan-and-write-a-budget-for-research-grant-proposal
#14
REVIEW
Satish G Patil
Medical research can have an enormous positive impact on human health. Health research improves the quality of human lives and society which plays a vital role in social and economic development of the nation. Financial support is crucial for research. However, winning a research grant is a difficult task. A successful grant-winning application requires two key elements: one is an innovative research problem with best probable idea/plan for tackling it and appropriate planning of budget. The aim of the present paper is to give an insight on funding agencies providing funding for health research including traditional Indian medicine (from an Indian perspective) and key points for planning and writing budget section of a grant application...
October 28, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29050883/evaluation-of-antimicrobial-potential-of-successive-extracts-of-ulmus-wallichiana-planch
#15
Kundan Singh Bora, Akhilesh Kumar, Gajraj Bisht
BACKGROUND: The plant Ulmus wallichiana Planch. is found in hills of Uttarakhand, India. Bark of U. wallichiana is commonly used as traditional healer for bone fracture of animals as well as human beings and also used as wound healer remedy. OBJECTIVE: The present study was designed to evaluate antimicrobial potential of various extracts of U. wallichiana bark. MATERIALS AND METHODS: Soxhlet extraction method was used for preparation of different extracts viz...
October 16, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29031949/evaluation-of-irimedadi-taila-as-an-adjunctive-in-treating-plaque-induced-gingivitis
#16
Shweta Patil, Siddhartha A Varma, Girish Suragimath, Keshava Abbayya, Sameer A Zope, Vishwajeet Kale
BACKGROUND: Ayurvedic drugs have been used since ancient times to treat diseases including periodontal diseases. Oral rinses made from ayurvedic medicines are used in periodontal therapy to control bleeding and reduce inflammation. OBJECTIVE: To evaluate the efficacy of herbal preparation (Irimedadi taila) on reduction of plaque induced gingivitis. MATERIALS AND METHODS: A total of 100 volunteers with clinical signs of mild to moderate gingivitis were selected and assigned to Group A (only scaling done) and Group B (scaling along with the use of Irimedadi taila)...
October 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28988684/a-potent-nutraceutical-combination-of-cinnamomum-cassia-nigella-sativa-for-type-1-diabetes-mellitus
#17
Ginpreet Kaur, Mihir Invally, Mohammed Kamil Khan, Priyanka Jadhav
BACKGROUND: Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional Indian system of medicine, for their medicinal properties. Both the herbs individually have been successfully evaluated for their preliminary antidiabetic potential. AIM: Herein, we dived deeper into antidiabetic properties of these herbs, by investigating the combinatorial effect of both herbs, on parameters of diabetes and further, as an adjunct to metformin therapy, for assessing the pharmacodynamics of herb-drug interaction in diabetes mellitus...
October 5, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28928008/effects-of-anti-lipid-peroxidation-of-punica-granatum-fruit-extract-in-endothelial-cells-induced-by-plasma-of-severe-pre-eclamptic-patients
#18
Isri Nasifah, Setyawati Soeharto, Mukhamad Nooryanto
BACKGROUND: Preeclampsia is a pregnancy disorder characterized by hypertension and proteinuria. This disorder involves oxidative stress and changes in endothelial homeostasis. OBJECTIVE: This study was aimed to seek whether an ethanolic extract of Punica granatum fruit inhibits 8-iso-PGFα formation and modulates nitric oxide (NO) in endothelial cells induced by plasma from pre-eclamptic patients. MATERIAL AND METHODS: Endothelial cells were cultured from human umbilical vein endothelial cells...
September 15, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28917550/antidiabetic-potential-of-methanolic-and-flavonoid-rich-leaf-extracts-of-synsepalum-dulcificum-in-type-2-diabetic-rats
#19
Olabisi T Obafemi, Clement A Akinmoladun, Tolulope M Olaleye, Stephen O Agboade, Amos A Onasanya
BACKGROUND: Synsepalum dulcificum is a plant indigenous to West Africa. The fruit is used to modify taste of foods to sweetness. OBJECTIVES: This study aims to investigate the antidiabetic potentials of both methanolic and flavonoid-rich leaf extracts of S. dulcificum (MSD and FSD respectively) in type 2 diabetic Wistar albino rats. MATERIALS AND METHODS: Sixty three rats were randomly distributed into nine groups of seven animals each with group 1 serving as the normal control...
September 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28869083/antifungal-effect-of-cow-s-urine-distillate-on-candida-species
#20
J M Hoh, B Dhanashree
BACKGROUND: Increase in resistance of Candida species, to routinely used antifungal agents has necessitated the quest for new drugs. Few studies have revealed that cow's urine can suppress the growth of pathogenic fungi. However there is no published report on antifungal effects of cow's urine on clinical Candida isolates. OBJECTIVE: The present study aims at exploring the antifungal potential of cow's urine on clinical isolates of Candida species. MATERIAL & METHODS: In this in-vitro experimental study four standard strains and 37 clinical isolates of Candida species were tested for their susceptibility to amphotericin B, fluconazole and voriconazole, by disk diffusion method...
August 30, 2017: Journal of Ayurveda and Integrative Medicine
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