Franziska Rosser, Erick Forno, John Brehm, Yueh-Ying Han, Nadia Boutaoui, Angel Colón-Semidey, María Alvarez, Edna Acosta-Pérez, Kristen S Kurland, John F Alcorn, Glorisa Canino, Juan C Celedón
Traffic-related air pollution (TRAP) may affect immune responses, including those in the TH2 and TH17 pathways. To examine whether TRAP is associated with plasma level of TH17-, TH1-, and TH2-related cytokines in children with and without asthma, a cross-sectional study of 577 children (ages 6-14 years) with (n = 294) and without (n = 283) asthma in San Juan (Puerto Rico) was performed. Residential distance to a major road was estimated using geocoded home addresses for study participants. A panel of 14 cytokines, enriched for the TH17 pathway, was measured in plasma...
September 1, 2016: Pediatric Allergy, Immunology, and Pulmonology