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Food & Function

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https://www.readbyqxmd.com/read/28198489/negative-effects-of-divalent-mineral-cations-on-the-bioaccessibility-of-carotenoids-from-plant-food-matrices-and-related-physical-properties-of-gastro-intestinal-fluids
#1
Joana Corte-Real, Marie Bertucci, Christos Soukoulis, Charles Desmarchelier, Patrick Borel, Elke Richling, Lucien Hoffmann, Torsten Bohn
Carotenoid intake and tissue levels have been frequently associated with reduced risk of chronic diseases. However, their bioavailability is low and influenced by many dietary related parameters. Divalent mineral cations have been suggested to interfere with carotenoid digestion and to hamper micellarization, a prerequisite for their uptake, via complexation of bile salts and precipitation of fatty acids. In the present investigation, we have evaluated the effects of increasing concentrations of magnesium (0-300 mg L(-1)), calcium (0-1500 mg L(-1)), zinc (0-200 mg L(-1)), and sodium (0-1500 mg L(-1); control monovalent cation), on carotenoid bioaccessibility from frequently consumed food items rich in carotenoids (tomato juice, carrot juice, apricot nectar, spinach and field salad), following simulated gastro-intestinal digestion...
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28198481/correction-relating-rheology-and-tribology-of-commercial-dairy-colloids-to-sensory-perception
#2
Laura Laguna, Grace Farrell, Michael Bryant, Ardian Morina, Anwesha Sarkar
Correction for 'Relating rheology and tribology of commercial dairy colloids to sensory perception' by Laura Laguna, et al., Food Funct., 2017, DOI: 10.1039/c6fo01010e.
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28197615/dietary-polyacetylenes-falcarinol-and-falcarindiol-isolated-from-carrots-prevents-the-formation-of-neoplastic-lesions-in-the-colon-of-azoxymethane-induced-rats
#3
Morten Kobaek-Larsen, Rime B El-Houri, Lars P Christensen, Issam Al-Najami, Xavier Fretté, Gunnar Baatrup
Falcarinol (FaOH) and falcarindiol (FaDOH) are found in many food plants of the Apiaceae family. Carrots are a major dietary source of these polyacetylenes. Feeding azoxymethane (AOM)-induced rats with carrots and purified FaOH have previously been shown to inhibit neoplastic transformations in the colon. FaOH and FaDOH have also shown to have a synergistic effect in vitro, resulting in a significant increased cytotoxic activity. Based on these findings the antineoplastic effect of FaOH and FaDOH (purity > 99%) was investigated in the AOM-induced rat model...
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28197590/rats-urinary-metabolomes-reveal-the-potential-roles-of-functional-foods-and-exercise-in-obesity-management
#4
Mohamed A Farag, N M Ammar, T E Kholeif, N S Metwally, N M El-Sheikh, Ludger A Wessjohann, A Z Abdel-Hamid
The complexity of the metabolic changes in obese individuals still presents a challenge for the understanding of obesity-related metabolic disruptions and for obesity management. In this study, a gas chromatography mass spectrometry (GC-MS) based metabolomics approach targeting urine metabolism has been applied to assess the potential roles of functional foods and exercise for obesity management in rats. Male albino rats diagnosed as obese via histopathology and biochemical assays were administered functional foods in common use for obesity management including pomegranate, grapefruit, and red cabbage juice extracts in parallel with swimming exercise...
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28197578/chemical-characterization-of-the-glycated-myofibrillar-proteins-from-grass-carp-ctenopharyngodon-idella-and-their-impacts-on-the-human-gut-microbiota-in-vitro-fermentation
#5
Kaining Han, Ye Yao, Shiyuan Dong, Sun Jin, Hang Xiao, Haohao Wu, Mingyong Zeng
In this study, the chemical characterization of glycoconjugates of myofibrillar proteins from grass carp conjugated with glucose via Maillard reaction for up to 24 h of dry-heating was investigated, and their impacts on the microbial community in vitro human fecal fermentation were firstly evaluated by high-throughput sequencing technologies. The glycation greatly increased the furosine levels in glycoconjugates, which reached the maximum level (2.87 ± 0.08 mg per 100 mg protein) for 9 h of heating, and resulted in the structural changes of myofibrillar proteins based on the sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and Fourier transform infrared spectroscopy (FTIR) analysis...
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28194454/in-vitro-genotoxicity-of-carcinogenic-asarone-isomers
#6
S Haupenthal, K Berg, M Gründken, S Vallicotti, M Hemgesberg, K Sak, D Schrenk, M Esselen
The present study focused on genotoxic properties of the carcinogenic phenylpropanoids α-asarone and β-asarone, which are found in several herbs and spices, such as Acorus calamus or Acorus gramineus. Cytotoxic and genotoxic effects were determined in human liver carinoma HepG2 cells, in hamster lung fibroblast V79 cells and in human cytochrome P450 1A2 and human sulfotransferase 1C2 transfected V79 cells (tV79). The Alamar blue assay was used to measure cytotoxicity of both isomers prior to the identification of DNA damaging properties by single cell gel electrophoresis (comet assay)...
February 14, 2017: Food & Function
https://www.readbyqxmd.com/read/28186518/understanding-perception-of-food-types-in-terms-of-their-structures-the-missing-links
#7
EDITORIAL
Elke Scholten
No abstract text is available yet for this article.
February 10, 2017: Food & Function
https://www.readbyqxmd.com/read/28186516/apple-and-pear-consumption-and-type-2-diabetes-mellitus-risk-a-meta-analysis-of-prospective-cohort-studies
#8
REVIEW
Xiao-Fei Guo, Bo Yang, Jun Tang, Jia-Jing Jiang, Duo Li
The conclusions from epidemiological studies are controversial between apple and pear consumption and type 2 diabetes mellitus (T2DM) risk. The present study aimed to investigate whether apple and pear consumption was inversely associated with T2DM risk, and to evaluate the potential dose-response relationship. The Cochrane library, Embase and PubMed databases were searched up to Nov 2016. Prospective cohort studies, which reported the association of apple and pear consumption with incidence of T2DM, were included...
February 10, 2017: Food & Function
https://www.readbyqxmd.com/read/28180212/kodo-millet-whole-grain-and-bran-supplementation-prevents-high-fat-diet-induced-derangements-in-a-lipid-profile-inflammatory-status-and-gut-bacteria-in-mice
#9
Siddhartha M Sarma, Pragyanshu Khare, Sneha Jagtap, Dhirendra P Singh, Ritesh K Baboota, Koteswaraiah Podili, Ravneet K Boparai, Jaspreet Kaur, Kamlesh K Bhutani, Mahendra Bishnoi, Kanthi Kiran Kondepudi
The protective role of kodo millet whole grain and bran supplementation in diet induced obesity has not been investigated. Here we have studied the role of kodo millet supplementation in age matched Swiss albino mice that were randomly divided into groups and fed their respective diets for 16 weeks. A high fat diet increased weight gain, reduced glucose tolerance, increased serum lipids, altered hepatic and adipocyte gene expression and caused dysbiosis in the intestinal beneficial bacteria. Kodo millet supplementation did not affect weight gain but it improved glucose tolerance and prevented an increase in the serum cholesterol and lipid parameters (P ≤ 0...
February 9, 2017: Food & Function
https://www.readbyqxmd.com/read/28174780/shedding-light-on-the-biological-and-chemical-fingerprints-of-three-achillea-species-a-biebersteinii-a-millefolium-and-a-teretifolia
#10
Gokhan Zengin, Abdurrahman Aktumsek, Ramazan Ceylan, Sengul Uysal, Andrei Mocan, Gokalp Ozmen Guler, M Fawzi Mahomoodally, Jasmina Glamočlija, Ana Ćirić, Marina Soković
Representatives of the Achillea genus are widely used as foods or nutraceuticals. Considering the increasing demand for herbal dietary supplements with health promoting effects, the objective of this research was to evaluate the biological and chemical profiles of different extracts (ethyl acetate, methanol and water) obtained from three Achillea species (A. biebersteinii, A. millefolium and A. teretifolia). The antioxidant (free radical scavenging (DPPH and ABTS), reducing power (CUPRAC and FRAP), metal chelating and phosphomolybdenum), enzyme inhibitory (anti-cholinesterase, anti-tyrosinase, anti-amylase and anti-glucosidase) and antimicrobial (antibacterial and antifungal) effects were assessed to investigate their biological profiles...
February 8, 2017: Food & Function
https://www.readbyqxmd.com/read/28174773/dietary-fibre-based-scfa-mixtures-promote-both-protection-and-repair-of-intestinal-epithelial-barrier-function-in-a-caco-2-cell-model
#11
Tingting Chen, Choon Young Kim, Amandeep Kaur, Lisa Lamothe, Maliha Shaikh, Ali Keshavarzian, Bruce R Hamaker
Impaired gut barrier function plays an important role in the development of many diseases such as obesity, inflammatory bowel disease, and in HIV infection. Dietary fibres have been shown to improve intestinal barrier function through their fermentation products, short chain fatty acids (SCFAs), and the effects of individual SCFAs have been studied. Here, different SCFA mixtures representing possible compositions from fibre fermentation products were studied for protective and reparative effects on intestinal barrier function...
February 8, 2017: Food & Function
https://www.readbyqxmd.com/read/28174772/collagen-peptides-ameliorate-intestinal-epithelial-barrier-dysfunction-in-immunostimulatory-caco-2-cell-monolayers-via-enhancing-tight-junctions
#12
Qianru Chen, Oliver Chen, Isabela M Martins, Hu Hou, Xue Zhao, Jeffrey B Blumberg, Bafang Li
Dysfunction of the intestinal barrier plays a key role in the pathogenesis of inflammatory bowel disease (IBD) and multiple organ failure. The effect of Alaska pollock skin-derived collagen and its 3 tryptic hydrolytic fractions, HCP (6 kDa retentate), MCP (3 kDa retentate) and LCP (3 kDa permeate) on TNF-α induced barrier dysfunction was investigated in Caco-2 cell monolayers. TNF-α induced barrier dysfunction was significantly attenuated by the collagen and its peptide fractions, especially LCP, compared to TNF-α treated controls (P < 0...
February 8, 2017: Food & Function
https://www.readbyqxmd.com/read/28170016/the-anti-obesity-effect-of-fermented-barley-extracts-with-lactobacillus-plantarum-dy-1-and-saccharomyces-cerevisiae-in-diet-induced-obese-rats
#13
Jiayan Zhang, Xiang Xiao, Ying Dong, Lani Shi, Tian Xu, Fei Wu
Fermented cereals have significant potential for improving the nutritional quality and health effects of foods and ingredients. In the present study, aqueous extracts of fermented barley with either Lactobacillus plantarum dy-1 or Saccharomyces cerevisiae were investigated for their anti-adipogenic effects in vitro and in vivo. Oral administration of an aqueous extract of fermented barley with Lactobacillus plantarum dy-1 (LFBE) significantly prevented body weight gain and fat mass increase, and improved lipid profiles and glucose tolerance in high fat diet-induced obese male rats...
February 7, 2017: Food & Function
https://www.readbyqxmd.com/read/28170007/lactucaxanthin-a-potential-anti-diabetic-carotenoid-from-lettuce-lactuca-sativa-inhibits-%C3%AE-amylase-and-%C3%AE-glucosidase-activity-in-vitro-and-in-diabetic-rats
#14
Sowmya Shree Gopal, Magisetty Jhansi Lakshmi, Gurunathan Sharavana, Gunaseelan Sathaiah, Yadahally N Sreerama, Vallikannan Baskaran
Intestinal and pancreatic α-amylase and α-glucosidase inhibitors offer an approach to lower the levels of post-prandial hyperglycemia through the control of dietary starch breakdown in digestion. This study hypothesized that lactucaxanthin (Lxn) in lettuce (Lactuca sativa) inhibits the activity of α-amylase and α-glucosidase. In this study, the interaction of Lxn with α-amylase and α-glucosidase in silico and its inhibitory effect on these enzymes were studied using in vitro and STZ-induced diabetic rat models...
February 7, 2017: Food & Function
https://www.readbyqxmd.com/read/28164200/contribution-of-the-phenolic-composition-to-the-antioxidant-anti-inflammatory-and-antitumor-potential-of-equisetum-giganteum-l-and-tilia-platyphyllos-scop
#15
Inés Jabeur, Natália Martins, Lillian Barros, Ricardo C Calhelha, Josiana Vaz, Lotfi Achour, Celestino Santos-Buelga, Isabel C F R Ferreira
Naturally-occurring phytochemicals have received pivotal attention in the last few years, due to the increasing evidence of biological activities. Thus, in the present study, the antioxidant, anti-inflammatory and antitumor potentials of hydroethanolic extracts rich in phenolic compounds obtained from Equisetum giganteum L. and Tilia platyphyllos Scop. were assessed and directly correlated with their content of phenolic compounds, by using HPLC-DAD-ESI/MS analysis. T. platyphyllos showed the higher bioactive potential, evaluated in terms of antioxidant (radical scavenging effects - 105 μg mL(-1), reducing power - 123 μg mL(-1), β-carotene bleaching inhibition - 167 μg mL(-1), and lipid peroxidation inhibition - 56 μg mL(-1)), anti-inflammatory (225 μg mL(-1) inhibited 50% of nitric oxide production) and antitumor (breast - 224 μg mL(-1); lung - 247 μg mL(-1); cervical - 195 μg mL(-1) and hepatocellular - 173 μg mL(-1) carcinoma cells) activity, without having cytotoxic effects (>400 μg mL(-1))...
February 6, 2017: Food & Function
https://www.readbyqxmd.com/read/28164198/sialoglycoprotein-isolated-from-the-eggs-of-gadus-morhua-enhances-fracture-healing-in-osteoporotic-mice
#16
Qiping Zhan, Xiong Gui, Fei Wang, Peng Yu, Meihui Zhao, Jingfeng Wang, Changhu Xue
Osteoporosis is a common disease in the elderly, which is related to fracture healing delay. In this study, the effects of treatment with sialoglycoprotein isolated from the eggs of Gadus morhua (Gm-SGP) on tibial fracture healing in ovariectomized (OVX) osteoporotic female C57BL/6J mice for 56 days post-fracture were investigated. The result showed that Gm-SGP treatment significantly increased serum angiogenic factors and bone formation markers on day 5 and 11 post-fracture when compared with the OVX group...
February 6, 2017: Food & Function
https://www.readbyqxmd.com/read/28164196/preventive-effect-of-silibinin-in-combination-with-pu-erh-tea-extract-on-non-alcoholic-fatty-liver-disease-in-ob-ob-mice
#17
Wen-Yi Hu, Xiao-Hui Ma, Wang-Yi Zhou, Xin-Xin Li, Ting-Ting Sun, He Sun
There are presently no miracle drugs for non-alcoholic fatty liver disease (NAFLD). This study investigates the synergistic effect of Silibinin combined with Pu-erh tea extract (PTE) against NAFLD and explores the suggested mechanism of action. Ob/ob mice were fed a high fat diet along with the oral administration of Silibinin (86 mg per kg per day), PTE (250 mg per kg per day) or their combination for 6 weeks. Their lean littermates who were fed with standard chow diet were used as the control group. The blood biochemical index and histopathological evaluation were analyzed...
February 6, 2017: Food & Function
https://www.readbyqxmd.com/read/28164195/a-potential-sex-dimorphism-in-the-relationship-between-bitter-taste-and-alcohol-consumption
#18
Emma Louise Beckett, Konsta Duesing, Lyndell Boyd, Zoe Yates, Martin Veysey, Mark Lucock
BACKGROUND: Bitterness is an innate aversive taste important in detecting potentially toxic substances, including alcohol. However, bitter compounds exist in many foods and beverages, and can be desirable, such as in beer. TAS2R38 is a well-studied bitter taste receptor with common polymorphisms. Some have reported relationships between TAS2R38 genotypes, bitter taste phenotype and alcohol intake, however results have been mixed. These mixed results may be explained by the varying taste properties of different alcoholic beverages or a sex dimorphism in responses...
February 6, 2017: Food & Function
https://www.readbyqxmd.com/read/28154877/dietary-5-demethylnobiletin-inhibits-cigarette-carcinogen-nnk-induced-lung-tumorigenesis-in-mice
#19
Mingyue Song, Xian Wu, Noppawat Charoensinphon, Minqi Wang, Jinkai Zheng, Zili Gao, Fei Xu, Zhengze Li, Fang Li, Jiazhi Zhou, Hang Xiao
5-Demethylnobiletin (5DN) is a unique citrus flavonoid with various beneficial bioactivities. In this study, we determined the inhibitory effects of 5DN and its two major metabolites in the 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis mouse model as well as in human and mouse lung cancer cell models. In NNK-treated female A/J mice, dietary administration of 5DN (0.025% or 0.05% w/w in the diet) significantly decreased both lung tumor multiplicity and tumor volume. Immunohistochemical analysis showed strong anti-proliferative effects of 5DN in lung tumors...
February 3, 2017: Food & Function
https://www.readbyqxmd.com/read/28154868/impact-of-liposomal-encapsulation-on-degradation-of-anthocyanins-of-black-carrot-extract-by-adding-ascorbic-acid
#20
Burcu Guldiken, Monika Gibis, Dilek Boyacioglu, Esra Capanoglu, Jochen Weiss
Black carrot anthocyanins are known to be relatively stable because they contain acylated anthocyanins. The degradation of vitamin C (l-ascorbic acid) on anthocyanins is a known fact in beverage systems. In this study, the effects of various liposomal systems, including black carrot extract (0.1%, 0.2%, 0.4% w/w) and lecithin (1%, 2%, 4% w/w), on the color and degradation of anthocyanin in different ascorbic acid (0.01%, 0.025%, 0.05%, 0.1% w/w) concentrations were examined via UV/VIS spectroscopy and visual control of the color...
February 3, 2017: Food & Function
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