Leslie Citrome, Christoph U Correll, Luis San, Scott L Zeller, Stuart Madden, Juan Gutierrez, Miguel Lopez-Toledano, Sunita N Misra, Enrique Carrazana, Adrian L Rabinowicz
Importance: The prompt effective treatment of acute agitation among patients with schizophrenia or bipolar disorder can alleviate distressing symptoms for the patient and decrease the risk of escalation to aggression and the potential for serious harm to the patient, health care providers, and others. Observations: A commonly used approach for the management of acute agitation has been the intramuscular administration of antipsychotic medications and/or benzodiazepines. However, US Food and Drug Administration-approved treatments with alternative routes of delivery now include inhaled loxapine powder and, more recently, dexmedetomidine sublingual film...
January 30, 2024: Primary Care Companion to CNS Disorders