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World Journal of Diabetes

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https://www.readbyqxmd.com/read/27895824/relationship-between-depression-and-diabetes-in-pregnancy-a-systematic-review
#1
Glynis P Ross, Henrik Falhammar, Roger Chen, Helen Barraclough, Ole Kleivenes, Ian Gallen
AIM: To systematically review the literature on women with both diabetes in pregnancy (DIP) and depression during or after pregnancy. METHODS: In this systematic literature review, PubMed/MEDLINE and EMBASE were searched (13 November 2015) using terms for diabetes (type 1, type 2, or gestational), depression, and pregnancy (no language or date restrictions). Publications that reported on women who had both DIP (any type) and depression or depressive symptoms before, during, or within one year after pregnancy were considered for inclusion...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27895823/effect-of-pioglitazone-on-nerve-conduction-velocity-of-the-median-nerve-in-the-carpal-tunnel-in-type-2-diabetes-patients
#2
Sudip Chatterjee, Debmalya Sanyal, Sourav Das Choudhury, Mili Bandyopadhyay, Suraj Chakraborty, Arabinda Mukherjee
AIM: To evaluate the impact of pioglitazone pharmacotherapy in median nerve electrophysiology in the carpal tunnel among type 2 diabetes patients. METHODS: The study was executed in patients with type 2 diabetes, treated with oral drugs, categorized under pioglitazone or non-pioglitazone group (14 in each group), and who received electrophysiological evaluation by nerve conduction velocity at baseline and 3 mo. RESULTS: At 3 mo, pioglitazone-category had inferior amplitude in sensory median nerve [8...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27895822/linagliptin-alleviates-fatty-liver-disease-in-diabetic-db-db-mice
#3
Svetlana V Michurina, Irina Ju Ishenko, Vadim V Klimontov, Sergey A Archipov, Natalia E Myakina, Marina A Cherepanova, Eugenii L Zavjalov, Galina V Koncevaya, Vladimir I Konenkov
AIM: To study the effects of linagliptin on the structural signs of non-alcoholic fatty liver disease (NAFLD) in db/db mice. METHODS: Male diabetic db/db mice (BKS.Cg-Dock7(m+)/(+)Lepr(db)/J) aged 10 wk received the dipeptidyl peptidase 4 (DPP4) inhibitor linagliptin (10 mg/kg) or saline as a placebo once per day by gavage for 8 wk. Intact db/db mice served as controls. Structural changes in the liver were analyzed from light and electron microscopic images of sections from intact, placebo-treated and linagliptin-treated animals...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27895821/implanting-1-1b4-human-%C3%AE-cell-pseudoislets-improves-glycaemic-control-in-diabetic-severe-combined-immune-deficient-mice
#4
Alastair D Green, Srividya Vasu, Neville H McClenaghan, Peter R Flatt
AIM: To investigate the potential of implanting pseudoislets formed from human insulin-releasing β-cell lines as an alternative to islet transplantation. METHODS: In this study, the anti-diabetic potential of novel human insulin releasing 1.1B4 β-cells was evaluated by implanting the cells, either as free cell suspensions, or as three-dimensional pseudoislets, into the subscapular region of severe combined immune deficient mice rendered diabetic by single high-dose administration of streptozotocin...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27895820/sleep-circadian-dysrhythmia-obesity-and-diabetes
#5
REVIEW
Gumpeny Ramachandra Sridhar, Narasimhadevara Santhi Nirmala Sanjana
Synchrony of biological processes with environmental cues developed over millennia to match growth, reproduction and senescence. This entails a complex interplay of genetic, metabolic, chemical, light, hormonal and hedonistic factors across life forms. Sleep is one of the most prominent rhythms where such a match is established. Over the past 100 years or so, it has been possible to disturb the synchrony between sleep-wake cycle and environmental cues. Development of electric lights, shift work and continual accessibility of the internet has disrupted this match...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27895819/nutrition-insulin-resistance-and-dysfunctional-adipose-tissue-determine-the-different-components-of-metabolic-syndrome
#6
REVIEW
Juan Antonio Paniagua
Obesity is an excessive accumulation of body fat that may be harmful to health. Today, obesity is a major public health problem, affecting in greater or lesser proportion all demographic groups. Obesity is estimated by body mass index (BMI) in a clinical setting, but BMI reports neither body composition nor the location of excess body fat. Deaths from cardiovascular diseases, cancer and diabetes accounted for approximately 65% of all deaths, and adiposity and mainly abdominal adiposity are associated with all these disorders...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795822/response-to-comment-on-statin-use-and-risk-of-diabetes-mellitus
#7
Bharti Chogtu, Rahul Magazine, Kurady Laxminarayana Bairy
In letter to the editor "Comment on: Statin use and risk of diabetes mellitus" authors found the statement "pravastatin 40 mg/d reduced the risk of diabetes by 30% in West of Scotland Coronary Prevention study" erroneous. As per our opinion the statement is right but had been referenced incorrectly.
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795821/predictors-of-hypoglycemia-in-insulin-treated-patients-with-type-2-diabetes-mellitus-in-basrah
#8
Dhuha Tarik Nassar, Omran S Habib, Abbas Ali Mansour
AIM: To measure the incidence and determinants (predictors) of hypoglycemia among patients with type 2 diabetes mellitus (T2DM) who were on insulin treatment for at least one year. METHODS: The present study is an out-patients based inquiry about the risk and predictors of hypoglycemia among patients with T2DM seeking care at the Al-Faiha Specialized Diabetes, Endocrine, and Metabolism Center, in Basrah over a period of 7 mo (from 15(th) of April, 2013 to 15(th) of October, 2013)...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795820/cost-of-illness-among-patients-with-diabetic-foot-ulcer-in-turkey
#9
Ergun Oksuz, Simten Malhan, Bilge Sonmez, Rukiye Numanoglu Tekin
AIM: To evaluate the annual cost of patients with Wagner grade 3-4-5 diabetic foot ulcer (DFU) from the public payer's perspective in Turkey. METHODS: This study was conducted focused on a time frame of one year from the public payer's perspective. Cost-of-illness (COI) methodology, which was developed by the World Health Organization, was used in the generation of cost data. By following a clinical path with the COI method, the main total expenses were reached by multiplying the number of uses of each expense item, the percentage of cases that used them and unit costs...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795819/impact-of-diabetes-mellitus-on-risk-of-cardiovascular-disease-and-all-cause-mortality-evidence-on-health-outcomes-and-antidiabetic-treatment-in-united-states-adults
#10
Longjian Liu, Barbara Simon, Jinggaofu Shi, Arshpreet Kaur Mallhi, Howard J Eisen
AIM: To examine the epidemic of diabetes mellitus (DM) and its impact on mortality from all-cause and cardiovascular disease (CVD), and to test the effect of antidiabetic therapy on the mortality in United States adults. METHODS: The analysis included a randomized population sample of 272149 subjects ages ≥ 18 years who participated in the National Health Interview Surveys (NHIS) in 2000-2009. Chronic conditions (hypertension, DM and CVD) were classified by participants' self-reports of physician diagnosis...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795818/glucagon-like-peptide-1-receptor-agonists-favorably-address-all-components-of-metabolic-syndrome
#11
REVIEW
Sanjay Chatterjee, Samit Ghosal, Saurav Chatterjee
Cardiovascular death is the leading cause of mortality for patients with type 2 diabetes mellitus. The etiology of cardiovascular disease in diabetes may be divided into hyperglycemia per se and factors operating through components of metabolic syndrome (MetS). Hyperglycemia causes direct injury to vascular endothelium and possibly on cardiac myocytes. MetS is a cluster of risk factors like obesity, hyperglycemia, hypertension and dyslipidemia. The incidence of this syndrome is rising globally. Glucagon-like peptide-1 receptor agonists (GLP-1RA) are a group of drugs, which address all components of this syndrome favorably...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795817/nitrate-nitrite-nitrosamines-exposure-and-the-risk-of-type-1-diabetes-a-review-of-current-data
#12
REVIEW
Zahra Bahadoran, Asghar Ghasemi, Parvin Mirmiran, Fereidoun Azizi, Farzad Hadaegh
The potential toxic effects of nitrate-nitrite-nitrosamine on pancreatic β cell have remained a controversial issue over the past two decades. In this study, we reviewed epidemiological studies investigated the associations between nitrate-nitrite-nitrosamines exposure, from both diet and drinking water to ascertain whether these compounds may contribute to development of type 1 diabetes. To identify relevant studies, a systematic search strategy of PubMed, Scopus, and Science Direct was conducted using queries including the key words "nitrate", "nitrite", "nitrosamine" with "type 1 diabetes" or "insulin dependent diabetes mellitus"...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27795816/update-on-pre-diabetes-focus-on-diagnostic-criteria-and-cardiovascular-risk
#13
REVIEW
Antonino Di Pino, Francesca Urbano, Salvatore Piro, Francesco Purrello, Agata Maria Rabuazzo
Pre-diabetes, which is typically defined as blood glucose concentrations higher than normal but lower than the diabetes threshold, is a high-risk state for diabetes and cardiovascular disease development. As such, it represents three groups of individuals: Those with impaired fasting glucose (IFG), those with impaired glucose tolerance (IGT) and those with a glycated haemoglobin (HbA1c) between 39-46 mmol/mol. Several clinical trials have shown the important role of IFG, IGT and HbA1c-pre-diabetes as predictive tools for the risk of developing type 2 diabetes...
October 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660698/diabetes-mellitus-and-cognitive-impairments
#14
REVIEW
Elham Saedi, Mohammad Reza Gheini, Firoozeh Faiz, Mohammad Ali Arami
There is strong evidence that diabetes mellitus increases the risk of cognitive impairment and dementia. Insulin signaling dysregulation and small vessel disease in the base of diabetes may be important contributing factors in Alzheimer's disease and vascular dementia pathogenesis, respectively. Optimal glycemic control in type 1 diabetes and identification of diabetic risk factors and prophylactic approach in type 2 diabetes are very important in the prevention of cognitive complications. In addition, hypoglycemic attacks in children and elderly should be avoided...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660697/in-vivo-corneal-confocal-microscopy-in-diabetes-where-we-are-and-where-we-can-get
#15
REVIEW
Ernesto Maddaloni, Francesco Sabatino
In vivo corneal confocal microscopy (IVCCM) is a novel, reproducible, easy and noninvasive technique that allows the study of the different layers of the cornea at a cellular level. As cornea is the most innervated organ of human body, several studies investigated the use of corneal confocal microscopy to detect diabetic neuropathies, which are invalidating and deadly complications of diabetes mellitus. Corneal nerve innervation has been shown impaired in subjects with diabetes and a close association between damages of peripheral nerves due to the diabetes and alterations in corneal sub-basal nerve plexus detected by IVCCM has been widely demonstrated...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660696/evidence-for-current-diagnostic-criteria-of-diabetes-mellitus
#16
REVIEW
Ritesh Kumar, Lakshmana Perumal Nandhini, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Muthupillai Vivekanadan
Diabetes mellitus is a non-communicable metabolic derangement afflicting several millions of individuals globally. It is associated with several micro and macrovascular complications and is also a leading cause of mortality. The unresolved issue is that of definition of the diagnostic threshold for diabetes. The World Health Organization and the American Diabetes Association (ADA) have laid down several diagnostic criteria for diagnosing diabetes and prediabetes based on the accumulating body of evidence.This review has attempted to analyse the scientific evidence supporting the justification of these differing criteria...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660695/update-on-the-treatment-of-type-2-diabetes-mellitus
#17
REVIEW
Juan José Marín-Peñalver, Iciar Martín-Timón, Cristina Sevillano-Collantes, Francisco Javier Del Cañizo-Gómez
To achieve good metabolic control in diabetes and keep long term, a combination of changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal glycated hemoglobin significantly, decreases risk of macrovascular and microvascular complications. At present there are different treatments, both oral and injectable, available for the treatment of type 2 diabetes mellitus (T2DM). Treatment algorithms designed to reduce the development or progression of the complications of diabetes emphasizes the need for good glycaemic control...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660694/entrapment-neuropathies-in-diabetes-mellitus
#18
REVIEW
Eugenia Rota, Nicola Morelli
Neuropathy is a common complication of diabetes mellitus (DM) with a wide clinical spectrum that encompasses generalized to focal and multifocal forms. Entrapment neuropathies (EN), which are focal forms, are so frequent at any stage of the diabetic disease, that they may be considered a neurophysiological hallmark of peripheral nerve involvement in DM. Indeed, EN may be the earliest neurophysiological abnormalities in DM, particularly in the upper limbs, even in the absence of a generalized polyneuropathy, or it may be superimposed on a generalized diabetic neuropathy...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27625747/treatment-of-diabetic-retinopathy-recent-advances-and-unresolved-challenges
#19
REVIEW
Michael W Stewart
Diabetic retinopathy (DR) is the leading cause of blindness in industrialized countries. Remarkable advances in the diagnosis and treatment of DR have been made during the past 30 years, but several important management questions and treatment deficiencies remain unanswered. The global diabetes epidemic threatens to overwhelm resources and increase the incidence of blindness, necessitating the development of innovative programs to diagnose and treat patients. The introduction and rapid adoption of intravitreal pharmacologic agents, particularly drugs that block the actions of vascular endothelial growth factor (VEGF) and corticosteroids, have changed the goal of DR treatment from stabilization of vision to improvement...
August 25, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27625746/assessment-of-the-cardiovascular-and-gastrointestinal-autonomic-complications-of-diabetes
#20
REVIEW
Christina Brock, Birgitte Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Niels Jessen, Adam D Farmer
The global prevalence of diabetes mellitus is increasing; arguably as a consequence of changes in diet, lifestyle and the trend towards urbanization. Unsurprisingly, the incidence of both micro and macrovascular complications of diabetes mirrors this increasing prevalence. Amongst the complications with the highest symptom burden, yet frequently under-diagnosed and sub-optimally treated, is diabetic autonomic neuropathy, itself potentially resulting in cardiovascular autonomic neuropathy and gastrointestinal (GI) tract dysmotility...
August 25, 2016: World Journal of Diabetes
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