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Journal of Advanced Research

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https://www.readbyqxmd.com/read/28053783/novel-angiotensin-converting-enzyme-inhibitory-peptides-from-caseins-and-whey-proteins-of-goat-milk
#1
Hisham R Ibrahim, Ahmed S Ahmed, Takeshi Miyata
Angiotensin-converting enzyme (ACE) plays a central role in blood pressure regulation by producing the vasoconstrictor angiotensin II. The inhibition of ACE with natural inhibitors, as alternatives to avoid the side effect of synthetic drugs, is a major target in the prevention of hypertension. In this study, we examined the separated caseins and whey proteins of goat milk for the presence of ACE inhibitory peptides. Digestion of isolated whey proteins and caseins of goat milk by gastric pepsin generated soluble hydrolysates exhibiting significant inhibition of ACE compared to weak inhibition by undigested proteins...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28053782/dexamethasone-abrogates-the-antimicrobial-and-antibiofilm-activities-of-different-drugs-against-clinical-isolates-of-staphylococcus-aureus-and-pseudomonas-aeruginosa
#2
Aquila Rodrigues, André Gomes, Pedro Henrique Ferreira Marçal, Marcus Vinícius Dias-Souza
Staphylococcus aureus and Pseudomonas aeruginosa are part of the human microbiota and are also important bacterial pathogens, for which therapeutic options are lacking nowadays. The combined administration of corticosteroids and antimicrobials is commonly used in the treatment of infectious diseases to control inflammatory processes and to minimize potential toxicity of antimicrobials, avoiding sequelae. Although different pharmaceutical dosage forms of antimicrobials combined to corticosteroids are available, studies on the interference of corticosteroids on the pharmacological activity of antimicrobials are scarce and controversial...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27980864/pulsed-magnetic-field-versus-ultrasound-in-the-treatment-of-postnatal-carpal-tunnel-syndrome-a-randomized-controlled-trial-in-the-women-of-an-egyptian-population
#3
Dalia M Kamel, Nashwa S Hamed, Neveen A Abdel Raoof, Sayed A Tantawy
The aim of this study was to compare the effects of pulsed electromagnetic field versus pulsed ultrasound in treating patients with postnatal carpal tunnel syndrome. The study was a randomized, double-blinded trial. Forty postnatal female patients with idiopathic carpal tunnel syndrome were divided randomly into two equal groups. One group received pulsed electromagnetic field, with nerve and tendon gliding exercises for the wrist, three times per week for four weeks. The other group received pulsed ultrasound and the same wrist exercises...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27942417/quantitative-structure-activity-relationship-and-molecular-docking-studies-of-a-series-of-quinazolinonyl-analogues-as-inhibitors-of-gamma-amino-butyric-acid-aminotransferase
#4
Usman Abdulfatai, Adamu Uzairu, Sani Uba
Quantitative structure-activity relationship and molecular docking studies were carried out on a series of quinazolinonyl analogues as anticonvulsant inhibitors. Density Functional Theory (DFT) quantum chemical calculation method was used to find the optimized geometry of the anticonvulsants inhibitors. Four types of molecular descriptors were used to derive a quantitative relation between anticonvulsant activity and structural properties. The relevant molecular descriptors were selected by Genetic Function Algorithm (GFA)...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27900210/a-new-lpv-modeling-approach-using-pca-based-parameter-set-mapping-to-design-a-pss
#5
Mohammad B Abolhasani Jabali, Mohammad H Kazemi
This paper presents a new methodology for the modeling and control of power systems based on an uncertain polytopic linear parameter-varying (LPV) approach using parameter set mapping with principle component analysis (PCA). An LPV representation of the power system dynamics is generated by linearization of its differential-algebraic equations about the transient operating points for some given specific faults containing the system nonlinear properties. The time response of the output signal in the transient state plays the role of the scheduling signal that is used to construct the LPV model...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27895938/understanding-colonization-and-proliferation-potential-of-endophytes-and-pathogen-in-planta-via-plating-polymerase-chain-reaction-and-ergosterol-assay
#6
Yiing Yng Chow, Sadequr Rahman, Adeline Su Yien Ting
This study aimed to establish the colonization behavior and proliferation potential of three endophytes and one pathogen Ganoderma boninense (Gb) introduced into oil palm ramets (host model). The endophytes selected were Diaporthe phaseolorum (WAA02), Trichoderma asperellum (T2), and Penicillium citrinum (BTF08). Ramets were first inoculated with 100 mL of fungal cells (10(6) cfu mL(-)(1)) via soil drenching. For the next 7 days, ramets were sampled and subjected to three different assays to detect and identify fungal colonization, and establish their proliferation potential in planta...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27872759/impact-of-moderate-intensity-aerobic-exercise-on-chemotherapy-induced-anemia-in-elderly-women-with-breast-cancer-a-randomized-controlled-clinical-trial
#7
Heba M Mohamady, Hany F Elsisi, Yasser M Aneis
Exercises are often recommended for patients suffering from anemia to improve physical conditioning and hematologic parameters. Hence, the present study aimed to investigate the impact of moderate intensity aerobic exercise on chemotherapy-induced anemia. Thirty elderly women with breast cancer underwent chemotherapy and were randomly assigned into two equal groups; Group A received aerobic exercise for 25-40 min at 50-70% of the maximum heart rate, 3 times/week for 12 weeks in addition to usual daily living activities, medication and nutritional support...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27872758/thrombosis-of-iliac-vessels-a-rare-complication-of-endometriosis-case-report-and-review-of-literature
#8
Rita Chiaramonte, Salvatore Castorina, Emilio Giovanni Castorina, Alessandra Panarello, Salvatore Alessandro Maria Antoci
A young women presented with iliac vein thrombosis, as extrapelvic endometriosis complication. Endometriosis mass had a subfascial position at the level of external oblique muscle and extended to the iliac vein. This paper reviewed the literature on endometriosis cases localized into striated muscles and cases of deep vein thrombosis due to this disease. There are not similar cases in the literature. The diagnostic role of ultrasound, in obtaining the definitive histological diagnosis, may be further enhanced through Elasticity Imaging Techniques and ultrasound-guided biopsy...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857852/diamond-grinding-wheels-production-study-with-the-use-of-the-finite-element-method
#9
J Kundrák, V Fedorovich, A P Markopoulos, I Pyzhov, N Kryukova
Research results on 3D modeling of the diamond grain and its bearing layer when sintering diamond grinding wheels are provided in this paper. The influence of the main characteristics of the wheel materials and the wheel production process, namely the quantity of metallic phase within diamond grain, coefficient of thermal expansion of the metallic phase, the modulus of elasticity of bond material and sintering temperature, on the internal stresses arising in grains is investigated. The results indicate that the stresses in the grains are higher in the areas around the metallic phase...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857851/parameter-estimation-of-breast-tumour-using-dynamic-neural-network-from-thermal-pattern
#10
Elham Saniei, Saeed Setayeshi, Mohammad Esmaeil Akbari, Mitra Navid
This article presents a new approach for estimating the depth, size, and metabolic heat generation rate of a tumour. For this purpose, the surface temperature distribution of a breast thermal image and the dynamic neural network was used. The research consisted of two steps: forward and inverse. For the forward section, a finite element model was created. The Pennes bio-heat equation was solved to find surface and depth temperature distributions. Data from the analysis, then, were used to train the dynamic neural network model (DNN)...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857850/response-surface-and-neural-network-based-predictive-models-of-cutting-temperature-in-hard-turning
#11
Mozammel Mia, Nikhil R Dhar
The present study aimed to develop the predictive models of average tool-workpiece interface temperature in hard turning of AISI 1060 steels by coated carbide insert. The Response Surface Methodology (RSM) and Artificial Neural Network (ANN) were employed to predict the temperature in respect of cutting speed, feed rate and material hardness. The number and orientation of the experimental trials, conducted in both dry and high pressure coolant (HPC) environments, were planned using full factorial design. The temperature was measured by using the tool-work thermocouple...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857849/in-vitro-effect-of-seven-essential-oils-on-the-reproduction-of-the-cattle-tick-rhipicephalus-microplus
#12
Rafael Pazinato, Andréia Volpato, Matheus D Baldissera, Roberto C V Santos, Dilmar Baretta, Rodrigo A Vaucher, Janice L Giongo, Aline A Boligon, Lenita Moura Stefani, Aleksandro Schafer Da Silva
The acaricidal effect of seven essential oils was examined in vitro against the cattle tick (Rhipicephalus microplus). Engorged female ticks were manually collected in farms of Southern Brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (Juniperus communis), palmarosa (Cymbopogon martinii), cedar (Cedrus atlantica), lemon grass (Cymbopogon citratus), ginger (Zingiber officinale), geranium (Pelargonium graveolens) and bergamot (Citrus aurantium var bergamia) at concentrations of 1%, 5%, and 10% each...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857848/the-effect-of-%C3%AE-1-antitrypsin-deficiency-combined-with-increased-bacterial-loads-on-chronic-obstructive-pulmonary-disease-pharmacotherapy-a-prospective-parallel-controlled-pilot-study
#13
Marwa G Hennawy, Noha M Elhosseiny, Hussein Sultan, Wael Abdelfattah, Yousry Akl, Nirmeen A Sabry, Ahmed S Attia
Chronic obstructive pulmonary disease (COPD) is caused by α1-antitrypsin deficiency (AATD) genetic susceptibility and exacerbated by infection. The current pilot study aimed at studying the combined effect of AATD and bacterial loads on the efficacy of COPD conventional pharmacotherapy. Fifty-nine subjects (29 controls and 30 COPD patients) were tested for genetic AATD and respiratory function. The bacterial loads were determined to the patients' group who were then given a long acting beta-agonist and corticosteroid inhaler for 6 months...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857847/low-cost-composites-based-on-porous-titania-apatite-surfaces-for-the-removal-of-patent-blue-v-from-water-effect-of-chemical-structure-of-dye
#14
C El Bekkali, H Bouyarmane, S Saoiabi, M El Karbane, A Rami, A Saoiabi, M Boujtita, A Laghzizil
Hydroxyapatite/titania nanocomposites (TiHAp) were synthesized from a mixture of a titanium alkoxide solution and dissolution products of a Moroccan natural phosphate. The simultaneous gelation and precipitation processes occurring at room temperature led to the formation of TiHAp nanocomposites. X-ray diffraction results indicated that hydroxyapatite and anatase (TiO2) were the major crystalline phases. The specific surface area of the nanocomposites increased with the TiO2 content. Resulting TiHAp powders were assessed for the removal of the patent blue V dye from water...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857846/optimization-of-nonlinear-quarter-car-suspension-seat-driver-model
#15
Mahesh P Nagarkar, Gahininath J Vikhe Patil, Rahul N Zaware Patil
In this paper a nonlinear quarter car suspension-seat-driver model was implemented for optimum design. A nonlinear quarter car model comprising of quadratic tyre stiffness and cubic stiffness in suspension spring, frame, and seat cushion with 4 degrees of freedom (DoF) driver model was presented for optimization and analysis. Suspension system was aimed to optimize the comfort and health criterion comprising of Vibration Dose Value (VDV) at head, frequency weighted RMS head acceleration, crest factor, amplitude ratio of head RMS acceleration to seat RMS acceleration and amplitude ratio of upper torso RMS acceleration to seat RMS acceleration along with stability criterion comprising of suspension space deflection and dynamic tyre force...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857845/an-improved-teaching-learning-based-robust-edge-detection-algorithm-for-noisy-images
#16
Sasirooba Thirumavalavan, Sasikala Jayaraman
This paper presents an improved Teaching Learning Based Optimization (TLO) and a methodology for obtaining the edge maps of the noisy real life digital images. TLO is a population based algorithm that simulates the teaching-learning mechanism in class rooms, comprising two phases of teaching and learning. The 'Teaching Phase' represents learning from the teacher and 'Learning Phase' indicates learning by the interaction between learners. This paper introduces a third phase denoted by "Avoiding Phase" that helps to keep the learners away from the worst students with a view of exploring the problem space more effectively and escaping from the sub-optimal solutions...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857844/analysis-of-the-pushing-phase-in-paralympic-cross-country-sit-skiers-class-lw10
#17
Laura Gastaldi, Stefano Mauro, Stefano Pastorelli
Paralympic Cross-Country sit-skiers use adaptive equipment, with a resulting gesture similar to double poling techniques adopted by able-bodied skiers. Despite the similarity, a specific attention on the gesture performed by sit-skiers is needed. The paper focuses on the sledge kinematic and on inertia effect of upper body motion which is translated in a propulsive effect in the early stage of the pushing cycle. In particular a group of 7 elite sit skiers of class LW10 were recorded with a video-based markerless motion capture technique during 1 km sprint Paralympic race...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27857843/green-synthesis-of-silver-nanoparticles-using-extract-of-parkia-speciosa-hassk-pods-assisted-by-microwave-irradiation
#18
Is Fatimah
This paper reports an investigation of the microwave-assisted synthesis of silver nanoparticles (Ag NPs) using extract of stinky bean (Parkia speciosa Hassk) pods (BP). The formation of Ag NPs was identified by instrumental analysis consists of UV-vis spectrophotometry, Fourier-transform infrared (FTIR) spectrophotometry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and particle size analysis. Furthermore, Ag NPs were used as antibacterial agents against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27812387/nitrilotriacetic-acid-functionalized-adansonia-digitata-biosorbent-preparation-characterization-and-sorption-of-pb-ii-and-cu-ii-pollutants-from-aqueous-solution
#19
Adewale Adewuyi, Fabiano Vargas Pereira
Nitrilotriacetic acid functionalized Adansonia digitata (NFAD) biosorbent has been synthesized using a simple and novel method. NFAD was characterized by X-ray Diffraction analysis technique (XRD), Scanning Electron Microscopy (SEM), Brunauer-Emmett-Teller (BET) surface area analyzer, Fourier Transform Infrared spectrometer (FTIR), particle size dispersion, zeta potential, elemental analysis (CHNS/O analyzer), thermogravimetric analysis (TGA), differential thermal analysis (DTA), derivative thermogravimetric analysis (DTG) and energy dispersive spectroscopy (EDS)...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27713840/in-silico-identification-of-t-type-calcium-channel-blockers-a-ligand-based-pharmacophore-mapping-approach
#20
Tamanna Gandhi, Anu R Melge, C Gopi Mohan
Limited progress has been made in the quest to identify both selective and non-toxic T-type calcium channel blocking compounds. The present research work was directed toward slaking the same by identifying the selective three dimensional (3D) pharmacophore map for T-type calcium channel blockers (CCBs). Using HipHop module in the CATALYST 4.10 software, both selective and non-selective HipHop pharmacophore maps for T-type CCBs were developed to identify its important common pharmacophoric features. HipHop pharmacophore map of the selective T-type CCBs contained six different chemical features, namely ring aromatic (R), positive ionizable (P), two hydrophobic aromatic (Y), hydrophobic aliphatic (Z), hydrogen bond acceptor (H) and hydrogen bond donor (D)...
November 2016: Journal of Advanced Research
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