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Frontiers in Psychiatry

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https://www.readbyqxmd.com/read/29238313/differential-neural-processing-of-social-exclusion-and-inclusion-in-adolescents-with-non-suicidal-self-injury-and-young-adults-with-borderline-personality-disorder
#1
Rebecca C Brown, Paul L Plener, Georg Groen, Dominik Neff, Martina Bonenberger, Birgit Abler
Introduction: Non-suicidal self-injury (NSSI) is a symptom of borderline personality disorder (BPD). However, NSSI often occurs independently of BPD. Altered neural processing of social exclusion has been shown in adolescents with NSSI and adults with BPD with additional alterations during social inclusion in BPD patients. Aims of this study were to investigate differences in neural processing of social inclusion and exclusion situations between adolescents with NSSI and young adults with BPD and NSSI...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29238312/impact-of-relationship-status-and-quality-family-type-on-the-mental-health-of-mothers-and-their-children-a-10-year-longitudinal-study
#2
Jasmin Hannighofer, Heather Foran, Kurt Hahlweg, Tanja Zimmermann
Mothers and children of single or unstable relationships have higher rates of mental health problems than those in stable two-parent families. Despite results that mothers and children of conflictual two-parent families also show impairments, most studies do not consider relationship quality. Therefore, the present study combines relationship status and relationship quality to a "family type." The present study compares German mothers and children of two-parent families with high relationship quality to those from two-parent families with a low quality, single mothers, and unstable families...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29238311/assessing-risk-of-bias-in-randomized-controlled-trials-for-autism-spectrum-disorder
#3
Paola Matiko Martins Okuda, Cheryl Klaiman, Jessica Bradshaw, Morganne Reid, Hugo Cogo-Moreira
Aim: To determine construct validity and reliability indicators of the Cochrane risk of bias (RoB) tool in the context of randomized clinical trials (RCTs) for autism spectrum disorder (ASD). Methods: Confirmatory factor analysis was used to evaluate a unidimensional model consisting of 9 RoB categorical indicators evaluated across 94 RCTs addressing interventions for ASD. Results: Only five of the nine original RoB items returned good fit indices and so were retained in the analysis...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29238310/parameter-based-evaluation-of-attentional-impairments-in-schizophrenia-and-their-modulation-by-prefrontal-transcranial-direct-current-stimulation
#4
Nadine Gögler, Irina Papazova, Tatiana Oviedo-Salcedo, Nina Filipova, Wolfgang Strube, Johanna Funk, Hermann J Müller, Kathrin Finke, Alkomiet Hasan
Background: Attentional dysfunctions constitute core cognitive symptoms in schizophrenia, but the precise underlying neurocognitive mechanisms remain to be elucidated. Methods: In this randomized, double-blind, sham-controlled study, we applied, for the first time, a theoretically grounded modeling approach based on Bundesen's Theory of Visual Attention (TVA) to (i) identify specific visual attentional parameters affected in schizophrenia and (ii) assess, as a proof of concept, the potential of single-dose anodal transcranial direct current stimulation (tDCS; 20 min, 2 mA) to the left dorsolateral prefrontal cortex to modulate these attentional parameters...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29238309/who-seeks-treatment-when-medicine-opens-the-door-to-pathological-gambling-patients-psychiatric-comorbidity-and-heavy-predominance-of-online-gambling
#5
Anders Håkansson, Emma Mårdhed, Mats Zaar
Background: Few studies have assessed treatment-seeking behavior and patient characteristics in pathological gambling focusing on psychiatric comorbidity, particularly in a setting of heavy exposure to online gambling. This study aimed to address patient characteristics in a novel health care-based treatment modality for pathological gambling, including potential associations between gambling types, psychiatric comorbidity, and gender. Methods: All patients undergoing structured assessment between January 2016 and April 2017 were included (N = 106), and patient records were reviewed for cooccurring psychiatric disorders and types of problem games...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29238308/duration-of-absence-from-work-is-related-to-psychopathology-personality-and-sociodemographic-variables-in-a-longitudinal-cohort
#6
Alex Gamma, Roman Schleifer, Ingeborg Warnke, Vladeta Ajdacic-Gross, Wulf Rössler, Jules Angst, Michael Liebrenz
Objective: To examine, in a non-clinical sample, the association of psychopathology, personality, sociodemographic information, and psychosocial indicators of non-occupational functioning with the duration of absence from work in the past 12 months. Method: A longitudinal community cohort of 591 adults from Switzerland was analyzed using multilevel ordered logistic regression, with several alternative models as robustness checks. Psychopathology was assessed using the total score (Global Severity Index) of the Symptom Check List-90 Revised...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29230184/neuroligin-2-r215h-mutant-mice-manifest-anxiety-increased-prepulse-inhibition-and-impaired-spatial-learning-and-memory
#7
Chia-Hsiang Chen, Pin-Wei Lee, Hsiao-Mei Liao, Pi-Kai Chang
Neuroligin 2 (NLGN2) is a postsynaptic adhesion protein that plays an essential role in synaptogenesis and function of inhibitory neuron. We previously identified a missense mutation R215H of the NLGN2 in a patient with schizophrenia. This missense mutation was shown to be pathogenic in several cell-based assays. The objective of this study was to better understand the behavioral consequences of this mutation in vivo. We generated a line of transgenic mice carrying this mutation using a recombinant-based method...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29225584/prevalence-rates-of-the-incubus-phenomenon-a-systematic-review-and-meta-analysis
#8
Marc L Molendijk, Harriët Montagne, Ouarda Bouachmir, Zeynep Alper, Jan-Pieter Bervoets, Jan Dirk Blom
Background: The incubus phenomenon is a paroxysmal sleep-related disorder characterized by compound hallucinations experienced during brief phases of (apparent) wakefulness. The condition has an almost stereotypical presentation, characterized by a hallucinated being that exerts pressure on the thorax, meanwhile carrying out aggressive and/or sexual acts. It tends to be accompanied by sleep paralysis, anxiety, vegetative symptoms, and feelings of suffocation. Its prevalence rate is unknown since, in prior analyses, cases of recurrent isolated sleep paralysis with/without an incubus phenomenon have been pooled together...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29225583/item-response-patterns-on-the-patient-health-questionnaire-8-in-a-nationally-representative-sample-of-us-adults
#9
Shinichiro Tomitaka, Yohei Kawasaki, Kazuki Ide, Maiko Akutagawa, Hiroshi Yamada, Ono Yutaka, Toshiaki A Furukawa
Recent studies have shown that item responses on the Center for Epidemiologic Studies Depression Scale (CES-D) and Kessler Screening Scale for Psychological Distress (K6) exhibit the same characteristic item response patterns among the general population. However, the distributional patterns of responses on the Patient Health Questionnaire-8 (PHQ-8) among the general population have not been adequately studied. Thus, we conducted a pattern analysis of PHQ-8 item responses among US adults. Data (18,446 individuals) were obtained from the 2015 Behavioral Risk Factor Surveillance Survey (BRFSS)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29225582/significant-need-for-a-french-network-of-expert-centers-enabling-a-better-characterization-and-management-of-treatment-resistant-depression-fondation-fondamental
#10
Antoine Yrondi, Djamila Bennabi, Emmanuel Haffen, Marion Garnier, Frank Bellivier, Thierry Bourgerol, Vincent Camus, Thierry D'Amato, Olivier Doumy, Frédéric Haesebaert, Jérôme Holtzmann, Christophe Lançon, Philippe Vignaud, Fanny Moliere, Isabel Nieto, Raphaëlle Marie Richieri, Philippe Domenech, Corentin Rabu, Luc Mallet, Liova Yon, Laurent Schmitt, Florian Stephan, Guillaume Vaiva, Michel Walter, Pierre-Michel Llorca, Philippe Courtet, Marion Leboyer, Wissam El-Hage, Bruno Aouizerate
Background: Major depression is characterized by (i) a high lifetime prevalence of 16-17% in the general population; (ii) a high frequency of treatment resistance in around 20-30% of cases; (iii) a recurrent or chronic course; (iv) a negative impact on the general functioning and quality of life; and (v) a high level of comorbidity with various psychiatric and non-psychiatric disorders, high occurrence of completed suicide, significant burden along with the personal, societal, and economic costs...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29218020/peripheral-immune-alterations-in-major-depression-the-role-of-subtypes-and-pathogenetic-characteristics
#11
Frank Euteneuer, Katharina Dannehl, Adriana Del Rey, Harald Engler, Manfred Schedlowski, Winfried Rief
Depression has been associated with peripheral inflammatory processes and alterations in cellular immunity. Growing evidence suggests that immunological alterations may neither be necessary nor sufficient to induce depression in general, but seem to be associated with specific features. Using baseline data from the Outcome of Psychological Interventions in Depression trial, this exploratory study examines associations between depression subtypes and pathogenetic characteristics (i.e., melancholic vs non-melancholic depression, chronic vs non-chronic depression, age of onset, cognitive-affective and somatic symptom dimensions) with plasma levels of C-reactive protein (CRP), interleukin (IL)-6, IL-10, and numbers of leukocyte subpopulations in 98 patients with major depression (MD) and 30 age and sex-matched controls...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29218019/dietary-n-3-polyunsaturated-fatty-acids-in-late-pregnancy-and-postpartum-depressive-symptom-among-japanese-women
#12
Minatsu Kobayashi, Kohei Ogawa, Naho Morisaki, Yukako Tani, Reiko Horikawa, Takeo Fujiwara
Background: The use of n-3 polyunsaturated fatty acids (n-3PUFA) in preventive or therapeutic modalities for postpartum depression, especially long-chain types such as eicosapentaenoic acid (EPA) and a docosahexaenoic acid (DHA), is of considerable interest. High n-3PUFA consumption has been reported among pregnant Japanese women. Therefore, analysis of this group could provide important insights into the relationship between postpartum depression and dietary n-3PUFA consumption. To further examine the relationship between the risk of postpartum depression and n-3PUFA consumption, we conducted a prospective hospital-based birth cohort study in Japan...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29213247/mediating-effects-of-global-negative-effect-expectancies-on-the-association-between-problematic-cannabis-use-and-social-anxiety
#13
Maria Di Blasi, Paola Cavani, Laura Pavia, Crispino Tosto, Sabina La Grutta, Rosa Lo Baido, Cecilia Giordano, Adriano Schimmenti
The relationship between social anxiety (SA) and cannabis use among adolescents and young adults is a highly debated topic. In this cross-sectional study, we tested whether cannabis use expectancies mediated the association between SA and cannabis use severity in a sample of 343 young adults (74.3% male) who used cannabis. They completed self-report measures for the screening of problematic cannabis use (Cannabis Use Problems Identification Test) and SA symptoms (Social Interaction Anxiety Scale and Social Phobia Scale)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209239/genetic-biomarkers-on-age-related-cognitive-decline
#14
REVIEW
Chieh-Hsin Lin, Eugene Lin, Hsien-Yuan Lane
With ever-increasing elder populations, age-related cognitive decline, which is characterized as a gradual decline in cognitive capacity in the aging process, has turned out to be a mammoth public health concern. Since genetic information has become increasingly important to explore the biological mechanisms of cognitive decline, the search for genetic biomarkers of cognitive aging has received much attention. There is growing evidence that single-nucleotide polymorphisms (SNPs) within the ADAMTS9, BDNF, CASS4, COMT, CR1, DNMT3A, DTNBP1, REST, SRR, TOMM40, circadian clock, and Alzheimer's diseases-associated genes may contribute to susceptibility to cognitive aging...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209238/disrupted-control-related-functional-brain-networks-in-drug-naive-children-with-attention-deficit-hyperactivity-disorder
#15
Jiejie Tao, Xueyan Jiang, Xin Wang, Huiru Liu, Andan Qian, Chuang Yang, Hong Chen, Jiance Li, Qiong Ye, Jinhui Wang, Meihao Wang
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disease featuring executive control deficits as a prominent neuropsychological trait. Executive functions are implicated in multiple sub-networks of the brain; however, few studies examine these sub-networks as a whole in ADHD. By combining resting-state functional MRI and graph-based approaches, we systematically investigated functional connectivity patterns among four control-related networks, including the frontoparietal network (FPN), cingulo-opercular network, cerebellar network, and default mode network (DMN), in 46 drug-naive children with ADHD and 31 age-, gender-, and intelligence quotient-matched healthy controls (HCs)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209237/decreased-left-putamen-and-thalamus-volume-correlates-with-delusions-in-first-episode-schizophrenia-patients
#16
Xiaojun Huang, Weidan Pu, Xinmin Li, Andrew J Greenshaw, Serdar M Dursun, Zhimin Xue, Haihong Liu, Zhening Liu
Background: Delusional thinking is one of the hallmark symptoms of schizophrenia. However, the underlying neural substrate for delusions in schizophrenia remains unknown. In an attempt to further our understanding of the neural basis of delusions, we explored gray matter deficits and their clinical associations in first-episode schizophrenia patients with and without delusions. Methods: Twenty-four first-episode schizophrenia patients with delusions and 18 without delusions as well as 26 healthy controls (HC) underwent clinical assessment and whole-brain structural imaging which were acquired a 3...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209236/implementation-intention-for-initiating-intuitive-eating-and-active-embodiment-in-obese-patients-using-a-smartphone-application
#17
Damien Brevers, Anne Rogiers, Alexis Defontaine, Guy Cheron, Anne-Marie Clarinval, Jennifer Foucart, Anne Bouchez, Véronique Bolly, Laura Tsartsafloudakis, Pénélope Jottrand, Pierre Minner, Antoine Bechara, Charles Kornreich, Paul Verbanck
This article describes a study protocol, which aims to explore and describe the feasibility of a mobile-phone application for initiating intuitive eating and intuitive exercising in patients who are following an ambulatory treatment for obesity. Intuitive eating refers to one's ability to make food choices based on one's awareness of his/her body's response. Intuitive exercising encourages people in finding enjoyable ways of being physically active. These two components will be trained using an implementation intention procedure, that is, behavioral plans that aim at creating a strong link between a specified situation and a response...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209235/the-endless-trip-among-the-nps-users-psychopathology-and-psychopharmacology-in-the-hallucinogen-persisting-perception-disorder-a-systematic-review
#18
REVIEW
Laura Orsolini, Gabriele Duccio Papanti, Domenico De Berardis, Amira Guirguis, John Martin Corkery, Fabrizio Schifano
Hallucinogen-persisting perception disorder (HPPD) is a syndrome characterized by prolonged or reoccurring perceptual symptoms, reminiscent of acute hallucinogen effects. HPPD was associated with a broader range of LSD (lysergic acid diethylamide)-like substances, cannabis, methylenedioxymethamphetamine (MDMA), psilocybin, mescaline, and psychostimulants. The recent emergence of novel psychoactive substances (NPS) posed a critical concern regarding the new onset of psychiatric symptoms/syndromes, including cases of HPPD...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209234/altered-brain-functional-connectivity-in-betel-quid-dependent-chewers
#19
Xiaojun Huang, Weidan Pu, Haihong Liu, Xinmin Li, Andrew J Greenshaw, Serdar M Dursun, Zhimin Xue, Zhening Liu
Background: Betel quid (BQ) is a common psychoactive substance worldwide with particularly high usage in many Asian countries. This study aimed to explore the effect of BQ use on functional connectivity by comparing global functional brain networks and their subset between BQ chewers and healthy controls (HCs). Methods: Resting-state functional magnetic resonance imaging (fMRI) was obtained from 24 betel quid-dependent (BQD) male chewers and 27 healthy male individuals on a 3...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29204127/synthetic-aminoindanes-a-summary-of-existing-knowledge
#20
REVIEW
Nikola Pinterova, Rachel R Horsley, Tomas Palenicek
Objectives: Aminoindanes ("bath salts," a class of novel psychoactive substances, NPSs) increased rapidly in popularity on the recreational drug market, particularly after mephedrone and other synthetic cathinones were banned in the UK in 2010. Novel aminoindanes continue to emerge, but relatively little is known about their effects and risks. Their history, chemistry, pharmacology, behavioral effects, pharmacokinetics, and toxicity are reviewed in this paper. Methods: Scientific literature was searched on ISI Web of Knowledge: Web of Science (WoS) during June and July 2017, using English language terms: aminoindanes such as 5,6-methylenedioxy-2-aminoindane (MDAI), 5-iodo-2-aminoindane (5-IAI), 2-aminoindane (2-AI), 5,6-methylenedioxy-N-methyl-2-aminoindane (MDMAI), and 5-methoxy-6-methyl-2-aminoindane (MMAI)...
2017: Frontiers in Psychiatry
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