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Frontiers in Psychiatry

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https://www.readbyqxmd.com/read/29033861/neuropsychological-impairment-in-detoxified-alcohol-dependent-subjects-with-preserved-psychosocial-functioning
#1
Catherine Martelli, Amélie Petillion, Marine Brunet-Lecomte, Rubén Miranda Marcos, Sandra Chanraud, Ammar Amirouche, Alexia Letierce, Nikoleta Kostogianni, Hervé Lemaitre, Henri-Jean Aubin, Lisa Blecha, Michel Reynaud, Jean-Luc Martinot, Amine Benyamina
BACKGROUND: Chronic alcoholism and its related cognitive impairments are associated with increased social, relational, and professional deficits which have a variable overall impact on social integration. These impairments are known to have varying severities and have rarely been studied among healthy alcohol-dependent subjects with preserved psychosocial functioning. Thus, the objective of this study is to describe neuropsychological performance in this particular population. METHOD: Twenty-nine socially adjusted alcohol-dependent men, hospitalized for a first or second withdrawal and abstinent for 3 weeks minimum, were compared to 29 healthy non-alcoholic controls...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033860/olfactory-functioning-and-depression-a-systematic-review
#2
REVIEW
Hannah Taalman, Caroline Wallace, Roumen Milev
BACKGROUND: Research has demonstrated a reduction in olfactory functioning in patients with schizophrenia. This research has led to examination of olfactory functioning in other mental disorders, such as depression. There is a great deal of variation in the results generated from such research, and it remains unclear as to how olfactory functioning is associated with or impacted by depression. METHOD: The current review examined the literature in accordance with PRISMA guidelines in order to generate a better understanding of this relationship and to identify if and what aspects of olfactory processing are altered...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033859/multi-watt-near-infrared-phototherapy-for-the-treatment-of-comorbid-depression-an-open-label-single-arm-study
#3
Theodore A Henderson, Larry D Morries
BACKGROUND: The treatment of depression has been hampered by low efficacy of antidepressant medications and safety concerns with alternative modalities. Recent work demonstrated that multi-Watt transcranial near-infrared light therapy (NILT) can effectively treat traumatic brain injury (TBI). The current objective is to explore multi-Watt NILT efficacy in a proof-of-concept study as a treatment for depression. METHODS: Thirty-nine sequential patients treated for TBI between March 2013 and May 2017 provided depression self-assessment data and/or were administered the Hamilton depression rating scale...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033858/honosca-d-as-a-measure-of-the-severity-of-diagnosed-mental-disorders-in-children-and-adolescents-psychometric-properties-of-the-german-translation
#4
Agnes von Wyl, Stephan Toggweiler, Ruedi Zollinger
The Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA), in use worldwide, is a 13-item measure assessing the biopsychosocial severity of mental health problems in children and adolescents. This article introduces the authorized German-language version of HoNOSCA, the HoNOSCA-D, and examines and discusses its psychometric properties based on a clinical sample of 1,533 children and adolescents aged 4;0 to 17;11 years. For the HoNOSCA-D total score (severity of mental health problems), internal consistency (Cronbach's alpha) was 0...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033857/an-update-overview-on-brain-imaging-studies-of-internet-gaming-disorder
#5
REVIEW
Aviv M Weinstein
There are a growing number of studies on structural and functional brain mechanisms underlying Internet gaming disorder (IGD). Recent functional magnetic resonance imaging studies showed that IGD adolescents and adults had reduced gray matter volume in regions associated with attention motor coordination executive function and perception. Adolescents with IGD showed lower white matter (WM) integrity measures in several brain regions that are involved in decision-making, behavioral inhibition, and emotional regulation...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033856/possible-facilitative-effects-of-repeated-anodal-transcranial-direct-current-stimulation-on-functional-outcome-1-month-later-in-schizophrenia-an-open-trial
#6
Zui Narita, Takuma Inagawa, Kazuki Sueyoshi, Crystal Lin, Tomiki Sumiyoshi
Recent research on neuromodulation techniques, such as transcranial direct current stimulation (tDCS), for the treatment of schizophrenia has mainly focused on psychotic symptoms. We aimed to determine whether repetitive tDCS is efficacious in improving determinants of outcome, such as cognitive function, daily living skills, and depressive mood in patients with schizophrenia. Twenty-eight patients underwent tDCS (2 mA × 20 min) two times per day for 5 consecutive days. The anodal electrode was placed over the left dorsolateral prefrontal cortex while the cathodal electrode was placed over the right supraorbital region...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033855/implicit-recognition-of-familiar-and-unfamiliar-faces-in-schizophrenia-a-study-of-the-skin-conductance-response-in-familiarity-disorders
#7
Aurely Ameller, Aline Picard, Fabien D'Hondt, Guillaume Vaiva, Pierre Thomas, Delphine Pins
OBJECTIVE: Familiarity is a subjective sensation that contributes to person recognition. This process is described as an emotion-based memory-trace of previous meetings and could be disrupted in schizophrenia. Consequently, familiarity disorders could be involved in the impaired social interactions observed in patients with schizophrenia. Previous studies have primarily focused on famous people recognition. Our aim was to identify underlying features, such as emotional disturbances, that may contribute to familiarity disorders in schizophrenia...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29021765/enhancing-neuroplasticity-to-augment-cognitive-remediation-in-schizophrenia
#8
REVIEW
Carol Jahshan, Yuri Rassovsky, Michael F Green
There is a burgeoning need for innovative treatment strategies to improve the cognitive deficits in schizophrenia. Cognitive remediation (CR) is effective at the group level, but the variability in treatment response is large. Given that CR may depend on intact neuroplasticity to produce cognitive gains, it is reasonable to combine it with strategies that harness patients' neuroplastic potential. In this review, we discuss two non-pharmacological approaches that can enhance neuroplasticity and possibly augment the effects of CR in schizophrenia: physical exercise and transcranial direct current stimulation (tDCS)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29021764/multicomponent-intervention-for-patients-admitted-to-an-emergency-unit-for-suicide-attempt-an-exploratory-study
#9
Sebastien Brovelli, Yves Dorogi, Adam-Scott Feiner, Philippe Golay, Friedrich Stiefel, Charles Bonsack, Laurent Michaud
Suicide is a major cause of premature deaths worldwide and belongs to the top priority public health issues. While suicide attempt is the most important risk factor for completed suicide, intervention for suicide attempters (SA) have produced mixed results. Since an important proportion of SA request medical care, emergency units (EU) are an opportune setting to implement such interventions. This exploratory study evaluated the feasibility and acceptability of a multicomponent intervention for SA admitted to an EU...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29021763/the-functional-role-of-individual-alpha-based-frontal-asymmetry-in-the-evaluation-of-emotional-pictures-evidence-from-event-related-potentials
#10
Tao Suo, Lei Liu, Chaoyang Chen, Entao Zhang
The perceptual processing of emotional stimuli is subject to the regulation of brain function. This study investigated whether frontal electroencephalography (EEG) alpha asymmetry at resting conditions predicted the evaluation of emotional picture stimuli by event-related potentials (ERPs). In this study, participants first completed a 2-min resting task, and then passively viewed emotional pictures. The results showed that left active individuals had smaller frontal EEG alpha asymmetry scores to negative pictures than to positive and neutral pictures, whereas right active individuals had similar frontal EEG alpha asymmetry scores to negative, positive, and neutral pictures...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29018368/biclustered-independent-component-analysis-for-complex-biomarker-and-subtype-identification-from-structural-magnetic-resonance-images-in-schizophrenia
#11
Cota Navin Gupta, Eduardo Castro, Srinivas Rachkonda, Theo G M van Erp, Steven Potkin, Judith M Ford, Daniel Mathalon, Hyo Jong Lee, Bryon A Mueller, Douglas N Greve, Ole A Andreassen, Ingrid Agartz, Andrew R Mayer, Julia Stephen, Rex E Jung, Juan Bustillo, Vince D Calhoun, Jessica A Turner
Clinical and cognitive symptoms domain-based subtyping in schizophrenia (Sz) has been critiqued due to the lack of neurobiological correlates and heterogeneity in symptom scores. We, therefore, present a novel data-driven framework using biclustered independent component analysis to detect subtypes from the reliable and stable gray matter concentration (GMC) of patients with Sz. The developed methodology consists of the following steps: source-based morphometry (SBM) decomposition, selection and sorting of two component loadings, subtype component reconstruction using group information-guided ICA (GIG-ICA)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29018367/treatment-of-comorbid-alcohol-dependence-and-anxiety-disorder-review-of-the-scientific-evidence-and-recommendations-for-treatment
#12
REVIEW
Carmen Gimeno, Marisa Luisa Dorado, Carlos Roncero, Nestor Szerman, Pablo Vega, Vicent Balanzá-Martínez, F Javier Alvarez
Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). "Co-occurring disorders" refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder. The aim of this study was to assess the effectiveness of psychopharmacological treatments and psychotherapy in patients with AUD and AnxD and to propose recommendations for the treatment of patients with comorbid AnxDs and AUDs. Randomized clinical trials, meta-analyses, and clinical guidelines were retrieved from PubMed, Embase, and Cochrane databases...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28993742/development-and-validation-of-the-amphetamine-type-stimulants-motive-questionnaire-in-a-clinical-population
#13
Daniela Thurn, Emmanuel Kuntsche, Jennifer Anna Weber, Jörg Wolstein
Approximately 35.7 million people world-wide use amphetamine-type stimulants (ATS) leading to a high demand for effective treatment. Understanding the motives behind ATS use is a necessary basis for preventive and therapeutic treatment. The objective of this study is to develop the Amphetamine-Type stimulants Motive Questionnaire (AMQ) and to confirm its construct and concurrent validity in respect to the first and the latest month of ATS use based on answers of 233 patients with ATS disorders (74.2% male; mean age: 31...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28993741/executive-control-and-striatal-resting-state-network-interact-with-risk-factors-to-influence-treatment-outcomes-in-alcohol-use-disorder
#14
Milky Kohno, Laura E Dennis, Holly McCready, William F Hoffman
Alterations within mesocorticolimbic terminal regions commonly occur with alcohol use disorder (AUD). As pathological drug-seeking behavior may arise as a consequence of alcohol-induced neuroadaptations, it is critical to understand how such changes increase the likelihood of relapse. This report examined resting-state functional connectivity (RSFC) using both a seed-based and model-free approach in individuals in treatment for AUD and how dysregulation of network connectivity contributes to treatment outcomes...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28993740/pharmacological-augmentation-of-psychosocial-and-remediation-training-efforts-in-schizophrenia
#15
REVIEW
Philip D Harvey, Michael Sand
Pharmacological approaches to cognitive enhancement have received considerable attention but have not had considerable success in improving their cognitive and functional targets. Other intervention strategies, such as cognitive remediation therapy (CRT), have been shown to enhance cognitive performance but have not been found to improve functional outcomes without additional psychosocial interventions. Recently, several studies have attempted to enhance the effects of CRT by adding pharmacological interventions to the CRT treatments...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28993739/increased-subjective-distaste-and-altered-insula-activity-to-umami-tastant-in-patients-with-bulimia-nervosa
#16
Rikukage Setsu, Yoshiyuki Hirano, Miki Tokunaga, Toru Takahashi, Noriko Numata, Koji Matsumoto, Yoshitada Masuda, Daisuke Matsuzawa, Masaomi Iyo, Eiji Shimizu, Michiko Nakazato
The aim of this study was to examine differences in brain neural activation in response to monosodium glutamate (MSG), the representative component of umami, between patients with bulimia nervosa (BN) and healthy women (HW) controls. We analyzed brain activity after ingestion of an MSG solution using functional magnetic resonance imaging (fMRI) in a group of women with BN (n = 18) and a group of HW participants (n = 18). Both groups also provided a subjective assessment of the MSG solution via a numerical rating scale...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28983262/feasibility-and-accessibility-of-a-tailored-intervention-for-informal-caregivers-of-people-with-severe-psychiatric-disorders-a-pilot-study
#17
Shyhrete Rexhaj, Claude Leclerc, Charles Bonsack, Philippe Golay, Jérôme Favrod
OBJECTIVES: This study aimed to assess the acceptability and feasibility of a new tailored intervention for informal caregivers: the Ensemble (Together) program. METHODS: An open pre-post within-subject comparison pilot study was conducted. Twenty-one informal caregivers completed the five-session Ensemble program. Two measurement tools were used: The Brief Symptom Inventory (BSI) and the Life Orientation Scale (LOT-R). RESULTS: The results showed that informal caregivers were in need of individual support and were ready to participate in the Ensemble program independent of the patient's diagnosis or stage of illness...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28983261/persistency-of-cannabis-use-predicts-violence-following-acute-psychiatric-discharge
#18
Jules R Dugré, Laura Dellazizzo, Charles-Édouard Giguère, Stéphane Potvin, Alexandre Dumais
BACKGROUND: Violence is a major concern and is prevalent across several mental disorders. The use of substances has been associated with an exacerbation of psychiatric symptoms as well as with violence. Compared to other substances such as alcohol and cocaine, existing literature on the cannabis-violence relationship has been more limited, with most studies being conducted in the general population, and has shown controversial results. Evidence has suggested a stronger relationship when examining the effects of the persistency of cannabis use on future violent behaviors...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28983260/common-marmosets-a-potential-translational-animal-model-of-juvenile-depression
#19
Nicole Leite Galvão-Coelho, Ana Cecília de Menezes Galvão, Flávia Santos da Silva, Maria Bernardete Cordeiro de Sousa
Major depression is a psychiatric disorder with high prevalence in the general population, with increasing expression in adolescence, about 14% in young people. Frequently, it presents as a chronic condition, showing no remission even after several pharmacological treatments and persisting in adult life. Therefore, distinct protocols and animal models have been developed to increase the understanding of this disease or search for new therapies. To this end, this study investigated the effects of chronic social isolation and the potential antidepressant action of nortriptyline in juvenile Callithrix jacchus males and females by monitoring fecal cortisol, body weight, and behavioral parameters and searching for biomarkers and a protocol for inducing depression...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28983259/remission-of-psychosis-in-treatment-resistant-schizophrenia-following-bone-marrow-transplantation-a-case-report
#20
Tsuyoshi Miyaoka, Rei Wake, Sadayuki Hashioka, Maiko Hayashida, Arata Oh-Nishi, Ilhamuddin Abdul Azis, Muneto Izuhara, Keiko Tsuchie, Tomoko Araki, Ryosuke Arauchi, Rostia Arianna Abdullah, Jun Horiguchi
The authors present the case of a 24-year-old male with treatment-resistant schizophrenia, with predominant severe delusion and hallucination, who received bone marrow transplantation (BMT) for acute myeloid leukemia. After BMT, he showed a remarkable reduction in psychotic symptoms without administration of neuroleptics. He also showed drastic improvement in social functioning. Follow-up evaluations 2 and 4 years after BMT showed persistent significant improvement of the psychotic state and social functioning...
2017: Frontiers in Psychiatry
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