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Frontiers in Psychiatry

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https://www.readbyqxmd.com/read/28303109/the-effect-of-abuse-history-on-adolescent-patients-with-feeding-and-eating-disorders-treated-through-psychodynamic-therapy-comorbidities-and-outcome
#1
Annamaria M Strangio, Lucio Rinaldi, Gianluigi Monniello, Leuconoe Grazia Sisti, Chiara de Waure, Luigi Janiri
OBJECTIVES: The first aim of our study was to compare the characteristics and comorbidities of patients with eating disorders between those who suffered from a childhood abuse and those who did not. Our second aim was to analyze the differences in the outcome of the psychodynamic therapy between abused and not abused patients. METHODS: Twenty-six adolescent patients with eating disorders were assessed. Adolescent were evaluated by a single expert psychiatrist by checklists and questionnaires: EDI 3, SCL 90, BIS11, Dissociative Experiences Scale, Global Assessment of Functioning, SCID II, and CTQ-Self control (SF)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28289393/toward-a-symptom-guided-neurostimulation-for-gilles-de-la-tourette-syndrome
#2
REVIEW
Nicole Pedroarena-Leal, Diane Ruge
Therapy resistance of approximately one-third of patients with Gilles de la Tourette syndrome (GTS) requires consideration of alternative therapeutic interventions. This article provides a condensed review of the invasive and non-invasive stimulation techniques that have been applied, to date, for treatment and investigation of GTS. Through this perspective and short review, the article discusses potential novel applications for neurostimulation techniques based on a symptom-guided approach. The concept of considering the physiological basis of specific symptoms when using stimulation techniques will provide a platform for more effective non-pharmacological neuromodulation of symptoms in GTS...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28286486/using-virtual-reality-in-the-treatment-of-gambling-disorder-the-development-of-a-new-tool-for-cognitive-behavior-therapy
#3
Stéphane Bouchard, Geneviève Robillard, Isabelle Giroux, Christian Jacques, Claudie Loranger, Manon St-Pierre, Maxime Chrétien, Annie Goulet
Virtual reality (VR) can be used in the treatment of gambling disorder to provide emotionally charged contexts (e.g., induce cravings) where patients can practice cognitive behavior therapy (CBT) techniques in the safety of the therapist's office. This raises practical questions, such as whether the cravings are sufficient to be clinically useful but also manageable enough to remain clinically safe. Pilot data are also needed to test the development of a treatment manual and prepare large randomized control trials...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28265246/discrimination-and-psychological-distress-gender-differences-among-arab-americans
#4
Shervin Assari, Maryam Moghani Lankarani
BACKGROUND: Despite the existing knowledge on the association between discrimination and poor mental health, very few studies have explored gender differences in this association in Arab Americans. OBJECTIVE: The current study aimed to investigate whether gender moderates the association between the experience of discrimination and psychological distress in a representative sample of Arab Americans in Michigan. METHODS: Using data from the Detroit Arab American Study (DAAS), 2003, this study recruited Arab Americans (337 males, 385 females) living in Michigan, United States...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28261117/psychotropic-medication-and-substance-use-during-pregnancy-by-women-with-severe-mental-illness
#5
Kate J Brameld, Assen Jablensky, Jenny Griffith, John Dean, Vera A Morgan
BACKGROUND: Sociodemographic factors, alcohol and drug intake, and maternal health are known to be associated with adverse outcomes in pregnancy for women with severe mental illness in addition to their use of psychotropic medication. In this study, we describe the demographic characteristics of women hospitalized for severe mental illness along with their use of medication and other drugs during the pregnancy period. METHODS: A clinical case note review of women with psychosis who were hospitalized at the State Psychiatric Hospital in Western Australia during 1966-1996, gave birth between 1980 and 1992, and received psychiatric treatment during the pregnancy period...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28261116/red-flags-clinical-signs-for-identifying-autoimmune-encephalitis-in-psychiatric-patients
#6
Julia Herken, Harald Prüss
Autoimmune mechanisms causing diverse psychiatric symptoms are increasingly recognized and brought about a paradigm shift in neuropsychiatry. Identification of underlying antibodies against neuronal ion channels or receptors led to the speculation that a number of patients go misdiagnosed with a primary psychiatric disease. However, there is no clear consensus which clinical signs in psychiatric patients should prompt further investigations including measurement of anti-neuronal autoantibodies. We therefore aimed to analyze the presenting symptoms in patients with autoimmune encephalitis and the time between symptom onset and initiation of antibody diagnostics...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28261115/il1r2-ccr2-and-cxcr4-may-form-heteroreceptor-complexes-with-nmdar-and-d2r-relevance-for-schizophrenia
#7
Dasiel O Borroto-Escuela, Alexander O Tarakanov, Karl Bechter, Kjell Fuxe
The mild neuroinflammation hypothesis of schizophrenia was introduced by Bechter in 2001. It has been hypothesized that a hypofunction of glutamatergic signaling via N-methyl-D-aspartate receptors (NMDARs) and hyperactivation of dopamine D2 receptors play a role in schizophrenia. The triplet puzzle theory states that sets of triplet amino acid homologies guide two different receptors toward each other and contributes to the formation of a receptor heteromer. It is, therefore, proposed that putative NMDAR-C-C chemokine receptor type 2 (CCR2), NMDAR-C-X-C chemokine receptor type 4 (CXCR4), and NMDAR- interleukin 1 receptor type II (IL1R2) heteromers can be formed in the neuronal networks in mild neuroinflammation due to demonstration of Gly-Leu-Leu (GLL), Val-Ser-Thr (VST), and/or Ser-Val-Ser (SVS) amino acid homologies between these receptor protomers...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28243212/transient-dysregulation-of-dopamine-signaling-in-a-developing-drosophila-arousal-circuit-permanently-impairs-behavioral-responsiveness-in-adults
#8
Lachlan Ferguson, Alice Petty, Chelsie Rohrscheib, Michael Troup, Leonie Kirszenblat, Darryl W Eyles, Bruno van Swinderen
The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the likelihood of this disorder in adulthood. To test this hypothesis in a high-throughput animal model, we have transiently manipulated dopamine signaling in the developing fruit fly Drosophila melanogaster and examined behavioral responsiveness in adult flies. We found that either a transient increase of dopamine neuron activity or a transient decrease of dopamine receptor expression during fly brain development permanently impairs behavioral responsiveness in adults...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28243211/identifying-four-subgroups-of-trauma-in-psychosis-vulnerability-psychopathology-and-treatment
#9
Lucy H Stevens, Helen M Spencer, Douglas Turkington
No abstract text is available yet for this article.
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28243210/the-obesity-impulsivity-axis-potential-metabolic-interventions-in-chronic-psychiatric-patients
#10
REVIEW
Adonis Sfera, Carolina Osorio, Luzmin Acosta Inderias, Victoria Parker, Amy I Price, Michael Cummings
Pathological impulsivity is encountered in a broad range of psychiatric conditions and is thought to be a risk factor for aggression directed against oneself or others. Recently, a strong association was found between impulsivity and obesity which may explain the high prevalence of metabolic disorders in individuals with mental illness even in the absence of exposure to psychotropic drugs. As the overlapping neurobiology of impulsivity and obesity is being unraveled, the question asked louder and louder is whether they should be treated concomitantly...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28243209/editorial-psychobiological-research-in-psychosomatic-medicine
#11
EDITORIAL
Silvia Ouakinin, Marco Torrado, Susana Eusébio, David Barreira
No abstract text is available yet for this article.
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28243208/high-kynurenine-a-tryptophan-metabolite-predicts-remission-in-patients-with-major-depression-to-add-on-treatment-with-celecoxib
#12
Daniela Krause, Aye-Mu Myint, Christine Schuett, Richard Musil, Sandra Dehning, Anja Cerovecki, Michael Riedel, Volker Arolt, Markus J Schwarz, Norbert Müller
BACKGROUND: Signs of an inflammatory process have been described in major depression. METHODS: In a double-blind, randomized study of celecoxib or placebo add-on to reboxetine in 40 depressed patients, celecoxib treatment has beneficial effects. In order to evaluate the tryptophan/kynurenine metabolism and to identify predictors for remission, tryptophan (TRP), kynurenine (KYN), kynurenic acid (KYNA), and quinolinic acid (QUIN) were estimated in the serum of 32 patients before and after treatment and in a group of 20 healthy controls...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28239362/reducing-the-diagnostic-heterogeneity-of-schizoaffective-disorder
#13
Katherine Seldin, Kristan Armstrong, Max L Schiff, Stephan Heckers
OBJECTIVE: Clinical outcome studies of schizoaffective disorder patients have yielded conflicting results. One reason is the heterogeneity of samples drawn from the schizoaffective disorder population. Here, we studied schizoaffective disorder patients who showed marked functional impairment and continuous signs of illness for at least 6 months (i.e., DSM criteria B and C for schizophrenia). METHODS: We assessed 176 chronic psychosis patients with a structured interview (SCID-IV-TR) and the Diagnostic Interview for Genetic Studies schizoaffective disorder module...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28239361/deictic-and-propositional-meaning-new-perspectives-on-language-in-schizophrenia
#14
Vitor C Zimmerer, Stuart Watson, Douglas Turkington, I Nicol Ferrier, Wolfram Hinzen
Emerging linguistic evidence points at disordered language behavior as a defining characteristic of schizophrenia. In this article, we review this literature and demonstrate how a framework focusing on two core functions of language-reference and propositional meaning-can conceptualize schizophrenic symptoms, identify important variables for risk assessment, diagnosis, and treatment, and inform cognitive behavioral therapy and other remedial approaches. We introduce the linguistic phenomena of deictic anchoring and propositional complexity, explain how they relate to schizophrenic symptoms, and show how they can be tracked in language behavior...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28239360/grand-challenge-in-psychopharmacology-setting-priorities-to-shape-a-bright-future
#15
EDITORIAL
Roberto Ciccocioppo
No abstract text is available yet for this article.
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28228737/schizophrenia-associated-with-epileptiform-discharges-without-seizures-successfully-treated-with-levetiracetam
#16
Dominique Endres, Evgeniy Perlov, Bernd Feige, Dirk-Matthias Altenmüller, Nils Venhoff, Ludger Tebartz van Elst
BACKGROUND: Schizophrenia-like disorders can be divided into endogenic or primary, idiopathic, polygenetic forms, and different secondary, organic subgroups [e.g., (para)epileptic, immunological, degenerative]. Epileptic and paraepileptic explanatory approaches have a long tradition due to the high rate of electroencephalography (EEG) alterations in patients with schizophrenia. CASE PRESENTATION: We present the case of a 23-year-old female patient suffering, since the age of 14 years, from a fluctuating paranoid-hallucinatory syndrome with formal thought disorder, fear, delusions of persecution, auditory, visual, and tactile hallucinations, as well as negative and cognitive symptoms...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28220083/risperidone-effects-on-brain-dynamic-connectivity-a-prospective-resting-state-fmri-study-in-schizophrenia
#17
Kristin K Lottman, Nina V Kraguljac, David M White, Charity J Morgan, Vince D Calhoun, Allison Butt, Adrienne C Lahti
Resting-state functional connectivity studies in schizophrenia evaluating average connectivity over the entire experiment have reported aberrant network integration, but findings are variable. Examining time-varying (dynamic) functional connectivity may help explain some inconsistencies. We assessed dynamic network connectivity using resting-state functional MRI in patients with schizophrenia, while unmedicated (n = 34), after 1 week (n = 29) and 6 weeks of treatment with risperidone (n = 24), as well as matched controls at baseline (n = 35) and after 6 weeks (n = 19)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28220082/synaptic-and-neuronal-autoantibody-associated-psychiatric-syndromes-controversies-and-hypotheses
#18
Adam Al-Diwani, Thomas A Pollak, Alexander E Langford, Belinda R Lennox
Autoimmune encephalitis (AE) mediated by antibodies against synaptic and neuronal surface targets frequently presents with a psychiatric syndrome. In these patients, removal of autoantibodies treats the disease and outcomes are closely linked to early intervention. The discovery of these autoantibodies in isolated psychiatric syndromes has raised the possibility that these patients may derive similar benefits from immunotherapy, a potentially transformational approach to the treatment of mental illness. Although open-label case series suggest impressive therapeutic outcomes, the pathological relevance of these autoantibodies outside of canonical presentations is debated...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28217101/psychological-factors-and-alcohol-use-in-problematic-mobile-phone-use-in-the-spanish-population
#19
José De-Sola, Hernán Talledo, Gabriel Rubio, Fernando Rodríguez de Fonseca
This research aims to study the existing relationships among the factors of state anxiety, depression, impulsivity, and alcohol consumption regarding problematic mobile phone use, as assessed by the Mobile Phone Problem Use Scale. The study was conducted among 1,126 participants recruited among the general Spanish population, aged 16-65 years, by assessing the predictive value of these variables regarding this problematic use. Initially tobacco use was also considered being subsequently refused because of the low internal consistency of the scale used...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28210230/acute-mental-discomfort-associated-with-suicide-behavior-in-a-clinical-sample-of-patients-with-affective-disorders-ascertaining-critical-variables-using-artificial-intelligence-tools
#20
Susana Morales, Jorge Barros, Orietta Echávarri, Fabián García, Alex Osses, Claudia Moya, María Paz Maino, Ronit Fischman, Catalina Núñez, Tita Szmulewicz, Alemka Tomicic
AIM: In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE: To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD: A study involving 707 patients consulting for mental health issues in three health centers in Greater Santiago, Chile. Using 345 variables, an analysis was carried out with artificial intelligence tools, Cross Industry Standard Process for Data Mining processes, and decision tree techniques...
2017: Frontiers in Psychiatry
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