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Saudi Journal of Biological Sciences

Ayşen Melda Çolak
Not many chemical hormone studies does exist in our country especially in berry fruits. Foliar application of melatonin and gibberellic acid hormones was performed in 2016 and 2017 in order to analyze the effects of different doses of hormone applications on fruit quality and yield. Pheonologic, pomological and some bioactive content analyses of these hormones were studied. According to the research results, while M + GA10 ppm (240.50; 3.9) and M + GA 5 ppm (226.50; 3.6) applications have the highest fruit number and weight (g), the highest fruit size was obtained from GA 5 ppm (21...
September 2018: Saudi Journal of Biological Sciences
Behzad Salehi, Mansour Bayat, Mehrouz Dezfulian, Azar Sabokbar, Bahman Tabaraie
Fungal polysaccharides are well-known for the medicinal properties such as antitumor and immunomodulating effects. Hence, this study evaluated antitumor effects of polysaccharide extracted from Fusarium sp. isolated from soil samples of Karaj district, Alborz, Iran along with its taxonomic study. The filamentous fungus strain FK1 was isolated from the soil sample of Karaj, Iran. The strain was identified based on cultural, morphological and 18 S rRNA gene parameters as Fusarium . Further, the strain Fusarium was cultured in fermented broth of modified (PDB) for 10  days at 25 °C...
September 2018: Saudi Journal of Biological Sciences
Anis Ahamed, Ibrahim A Arif, Mohammed Mateen, Radhakrishnan Surendra Kumar, Akbar Idhayadhulla
A new series of 1,4-dihydropyridine derivatives ( 2a-h, 3a-e, and 4a-e) were systematically designed and synthesized via ultrasound irradiation methods with easy work-up and good yields. Compounds structures were confirmed by IR, 1 H NMR, 13 C NMR, and mass spectra. The synthesized compounds were screened for both antimicrobial and anticoagulant activities. Compound 2e (MIC: 0.25 μg/mL) was highly active against Escherichia coli and compound 2c (MIC: 0.5 μg/mL) was also highly active against Pseudomonas aeruginosa compared with ciprofloxacin...
September 2018: Saudi Journal of Biological Sciences
Lars Erichsen, Agnes Beermann, Marcos J Arauzo-Bravo, Mohamed Hassan, Mohamed A Dkhil, Saleh Al-Quraishy, Taghreed A Hafiz, Johannes C Fischer, Simeon Santourlidis
Aging associated DNA hypomethylation of LINE-1 and Alu retroelements may be a crucial determinant of loss of genomic integrity, deterioration and cancer. In peripheral blood LINE-1 hypomethylation has been reported to increase during aging, but other studies did not observe significant changes. We hypothesized that these apparently inconsistent reports might relate to differences between cellular and cell-free DNA. Using the technique of idiolocal normalization of real-time methylation-specific PCR (IDLN-MSP) for genetic imbalanced DNA specimens we obtained evidence that LINE-1 hypomethylation in cell-free DNA, but not cellular DNA from peripheral blood is an epigenetic biomarker for human aging...
September 2018: Saudi Journal of Biological Sciences
Wei Gao, Hualong Wu, Muhammad Kamran Siddiqui, Abdul Qudair Baig
As an effective modeling, analysis and computational tool, graph theory is widely used in biological mathematics to deal with various biology problems. In the field of microbiology, graph can express the molecular structure, where cell, gene or protein can be denoted as a vertex, and the connect element can be regarded as an edge. In this way, the biological activity characteristic can be measured via topological index computing in the corresponding graphs. In our article, we mainly study the biology features of biological networks in terms of eccentric topological indices computation...
September 2018: Saudi Journal of Biological Sciences
Lingfa Ma, Shuling He, Fenrui Li, Jingjun Yang, Yuwei Chang, Kentian Zhao, Ningyu Liu
To explore the reason causing low yield, poor quality of Inula helenium I. , this paper investigated the influence of different remained stem heights on the yield, quality and water consumption of Inula helenium I. in Gannan plateau area using field single factor randomized block method. Research results showed that Inula helenium I. which was cut before blooming period in the last ten-day of July with remained stem height of 25 cm had the lowest water consumption, the best underground root traits (including main root length, root diameter, and root dry weight per plant), and the highest yield which was higher that control group by 18...
September 2018: Saudi Journal of Biological Sciences
LeMing Jiang, DanFei Huang, ShaoPing Nie, MingYong Xie
Plantago species are used as traditional medicine in Asian and Europe. Polysaccharide isolated from the seeds of Plantago asiatica L. could stimulate maturation transformation of bone-marrow derived dendritic cells (DCs). We found that blocking p38, ERK1/2 and JNK MAPK signal transduction could significantly decreased the PLP-2 induced expression of MHC II, CD86 surface molecules on DCs. Blocking p38 and JNK signal also significantly inhibited the cytokine secretion of TNF-α and IL-12p70 as well, while blocking ERK1/2 signal only decreased the secretion of TNF-α...
September 2018: Saudi Journal of Biological Sciences
Juntao Chen, Shengbo Ge, Zhenling Liu, Dangquan Zhang, Wanxi Peng
Pterocarpus is often used to make high-grade furniture, with beneficial health functions on the human body. Therefore, this article with large fruit red sandalwood as an example, to explore its extract on the human body beneficial health care ingredients. FT-IR analysis, in the 2855-3421 cm-1 wave segment, ethyl acetate after extraction of large fruit red sandalwood powder infrared transmittance increased the maximum value; GC-MS analysis, large fruit red sandalwood in the human body with a cough and phlegm, detoxification and enhance human immunity and other effects...
September 2018: Saudi Journal of Biological Sciences
Hanjie He, Jieming Qin, Xuexiang Cheng, Keqin Xu, Linzuo Teng, Dangquan Zhang
Using Phellodendron chinense seedlings as material, and treated with different concentrations of exogenous 6-Benzylaminopurine (6-BA) and α-naphthyacetic acid (NAA), then observed the growth status. Furthermore, we detected the contents of chlorophyll and soluble sugar, the activities of antioxidases by spectrophotometry, and determined the contents of secondary metabolite by high performance liquid chromatograph. The results showed that different concentrations of exogenous 6-BA increases the fresh weights and plant heights of Phellodendron chinense seedlings, and enhances the contents of chlorophyll and soluble sugar...
September 2018: Saudi Journal of Biological Sciences
Juntao Chen
Pterocarpus a high-end, expensive furniture materials collectively. Pterocarpus and Pterocarpus products have a certain human health function. Therefore, this paper to Pterocarpus pedatus Pierre as an example, to study its extract on human health beneficial health care ingredients. FT-IR analysis showed that the infrared transmittance of Pterocarpus pedatus Pierre powder after ethanol/benzene extraction was the highest in the infrared spectrum of 400 cm-1 -800 cm-1 , 2750 cm-1 -3200 cm-1 wave number...
September 2018: Saudi Journal of Biological Sciences
Xinbin Zhou, Yingying Li, Fan Lai
Rice is the staple food for more than half of the world's population, but selenium (Se) is low in many rice growing countries. Water management model affects rice soil pH and Eh, and then affects the bioavailability of Se in soil. A pot experiment was conducted to investigate the effects of water management on soil Se species, dynamics and selenium uptake by rice plants. Sodium selenite was added to the soil so that the soil selenium content reached 0.5 mg kg-1 to study the effects of 3 different water management modes on soil selenium uptake by rice plants...
September 2018: Saudi Journal of Biological Sciences
Lihua Cao, Mingsan Miao, Jingyi Qiao, Ming Bai, Ruiqi Li
To investigate the protective mechanism of verbenalin on cerebral ischemia-reperfusion injury. Middle cerebral artery occlusion in the left hemisphere was induced in rats by filament insertion, and rat model of focal cerebral ischemia-reperfusion was established. The high, medium and low dose of verbenalin groups were injected in the tail vein of corresponding drugs 10 min before reperfusion, and submitted for 22 h of reperfusion after the operation. Mortality rate was then calculated, and neurological deficits of rats were scored...
September 2018: Saudi Journal of Biological Sciences
Xuefeng Wang, Lifei Wang, Shaoliang Lv, Teng Li
Connectivity between fish stocks is fundamental to the understanding of population dynamics and the implementation of sustainable fisheries management. Otolith microchemistry is a promising tool as it can provide information on the continuous growth of otoliths and the environmental effects on otolith composition. Such elemental fingerprints can help distinguish different stocks or life history stages, identify the origins or nursery areas of fish, and assess population structure. In this study, we examined the stock discrimination and spatial connectivity of cage-cultured and wild stocks of yellowfin seabream (Acanthopagrus latus) from the coastal waters of Shantou, Yangjiang, and Zhanjiang in China southern province Guangdong during 2012-2014, based on otolith trace-elemental signatures using multivariate statistical analysis and machine learning approaches...
September 2018: Saudi Journal of Biological Sciences
Yuanyuan Huang, Renbang Zhao, Weihua Liu, Yingjun Li, Penghui Zhang, Shuai Wang, Lin Wang
The nature chestnut endothelium, as waster source from chestnut ( Castaneamollissima ) has pigment effecting the process of adsorbing heavy metalions, and the decolorized endothelium has low adsorption capacity. In order to raise the adsorption capacity of heavy metal ions, the discolor endothelium was pretreated by acidic formaldehyde, cis-butenedioic acid and irradiation. Thermodynamic and kinetics model was fitted to the adsorption of Pb (II) and Cd(II) ions onto modified chestnut endothelium by cis-butenedioic acid...
September 2018: Saudi Journal of Biological Sciences
Hua-Wen Cheng, Jian-Guang He, Wen-Yan He
The main objective of the present research work was to evaluate the antitumor effects of ethanol extract of Semen Euphorbiae (EESE) in ACHN human renal carcinoma cells. The effects on apoptosis induction, cell cycle phase distribution and livin protein expression were also evaluated. MTT assay was used to assess cytotoxic effects of the extract while as clonogenic assay was used to evaluate effects on colony formation tendency. Inverted phase contrast and fluorescence microscopic techniques were used to evaluate effects of EESE on cellular morphology and apoptosis...
September 2018: Saudi Journal of Biological Sciences
Sheng-Qun Wang, Qiao Zhang, Chao Sun, Guang-Yao Liu
In this study, we mainly aimed at developing the Ifosfamide-loaded-lipid-core nanocapsules (IFS-LNC) to increase the therapeutic efficacy in osteosarcoma. The nanoparticle was prepared and evaluated in terms of physical, chemical and biological parameters. The lipid-core-nanocapsules were nanosized with narrow particle size distribution and exhibited a high loading capacity. The LNC displayed a sustained release profile of the drug suggesting its potential application in biomedical field and prolonged anticancer therapy...
September 2018: Saudi Journal of Biological Sciences
Hak-Jae Kim, Kyeong-Hun Park, Dong-Hwi Kim, Han-Jung Chae, Gi-Ho Sung, Young-Ock Kim
Recent research has confirmed that Panax ginseng ( P. ginseng ) has effect on cultured osteoblast of the mouse. In this study we aim to validate the usefulness of tibia quantification by correlating micro-computed tomographic (microCT) images with histology analysis in the aged male rats. A total of thirty - old male WISTAR rats were used and divided into ten 8 weeks rats and ten 112 weeks aged rats with vehicle and ten 112 weeks aged rats with P. ginseng (300 mg/kg/day). Daily oral administration of P...
September 2018: Saudi Journal of Biological Sciences
Junsang Oh, Deok-Hyo Yoon, Jae-Gu Han, Hyung-Kyoon Choi, Gi-Ho Sung
Metabolite profiling of Wolfiporia cocos (family: Polyporaceae) had been much advancement in recent days, and its analysis by nuclear magnetic resonance (NMR) spectroscopy has become well established. However, the highly important trait of W. cocos still needs advanced protocols despite some standardization. Partial least squares discriminant analysis (PLS-DA) was used as the multivariate statistical analysis of the 1 H NMR data set. The PLS-DA model was validated, and the key metabolites contributing to the separation in the score plots of different ethanol W...
September 2018: Saudi Journal of Biological Sciences
Javaid Iqbal, Shahzad Ahmad Bhutta, Abdulaziz S Alqarni, Ayman A Owayss, Mohammad Javed Ansari
Dusky cotton bug ( Oxycarenus spp.) has become a major insect pest for cotton crop in Pakistan. Transgenic cotton varieties provided resistance to a variety of insects pests. But, these are not safe for this emerging potential threat. In present study, nine transgenic cotton varieties (IUB-222, MNH-886, FH-142, CIM-599, A-555, CIM-602, NIAB-777, MNH - 786 and Bt- 666) were assessed for seasonal population dynamics of dusky cotton bug (DCB) under field conditions. All transgenic varieties showed a differential DCB population over the months and no transgenic variety was free from DCB population throughout the crop duration...
September 2018: Saudi Journal of Biological Sciences
Vadivelu Bharathi, R L Rengarajan, Ramalingam Radhakrishnan, Abeer Hashem, Elsayed Fathi Abd Allah, Abdulaziz A Alqarawi, Arumugam Vijaya Anand
Obesity is a global health burden due to lifestyle modifications that have a strong association with a high incidence of diseases, such as dyslipidemia, glucose intolerance, nonalcoholic fatty liver diseases, diabetes, hypertension, coronary heart disease and cancer. The aim of the present study is to investigate the protective effects of a Macrotyloma uniflurom formulation (MUF) against high-fat diet (HFD)-induced oxidative stress and inflammation in obese rats. Male albino Wistar rats were fed a high-fat diet for 6 weeks to facilitate fat-induced oxidative stress and were simultaneously treated with MUF (400 mg/kg b...
September 2018: Saudi Journal of Biological Sciences
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