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Therapeutic Hypothermia and Temperature Management

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https://www.readbyqxmd.com/read/30657435/esophageal-temperature-management-in-patients-suffering-from-traumatic-brain-injury
#1
Faraaz Bhatti, Melissa Naiman, Alexander Tsarev, Erik Kulstad
Traumatic brain injury (TBI) is a leading cause of death in the United States, and represents 2.5 million Emergency Department attendances, admissions into hospital, and deaths. A range of temperature modulating devices have been used to proactively cool TBI patients; however, there are currently no uniform targeted temperature management (TTM) guidelines in this patient population. Esophageal temperature management (ETM) is a relatively new TTM modality and the purpose of this study is to determine whether ETM is effective in controlling core temperature in TBI cases...
January 18, 2019: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30614777/current-advances-in-the-use-of-therapeutic-hypothermia
#2
Kees Polderman, Ahmed Hegazy, Justin Lundbye, Noel Watson
No abstract text is available yet for this article.
January 7, 2019: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30614768/studies-targeting-stroke-and-acute-myocardial-infarction
#3
Michael C Kurz, Patrick Lyden, Michael Dae, Marko Noc
No abstract text is available yet for this article.
January 7, 2019: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30614764/whole-body-cooling-and-erythropoietin-in-neonatal-cervical-spine-injury
#4
Juan Arnaez, María Miranda, Ester Riñones, Alfredo García-Alix
There is mounting experimental evidence that therapeutic hypothermia (TH) mitigates secondary mechanisms of spinal cord injury (SCI). There is a potential synergistic neuroprotective effect for SCI through the combination of TH and other promising therapies. The treatment of TH for SCI has promising results in adults, but its use is anecdotal in newborns with SCI. SCI is a rare, serious, and often fatal complication of instrumental delivery. For the first time, we describe the case of a male newborn infant with upper SCI who was born at term age and was offered whole-body cooling and erythropoietin treatment with unsuccessful outcome...
January 7, 2019: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30585772/factors-associated-with-the-transfer-decision-in-resuscitated-patients-with-out-of-hospital-cardiac-arrest-presenting-to-a-hospital-with-limited-targeted-temperature-management-capability-in-korea
#5
Sola Kim, Ki Ok Ahn, Young Sun Ro, Sang Do Shin
This study aimed to identify factors associated with the decision to transfer resuscitated patients with out-of-hospital cardiac arrest (OHCA) who were initially examined at hospitals with limited targeted temperature management capability (HLTC) in Korea. We included adult patients with OHCA who were initially transported to HLTC from 2012 to 2015. We limited the study population with OHCA who were admitted or transferred. Potential factors associated with the transfer decision were categorized as patient- or hospital-level characteristics...
December 26, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30585771/characterization-of-the-effect-of-prolonged-therapeutic-hypothermia-on-serum-magnesium-and-potassium-following-neurological-injury
#6
Caroline Beaulieu, Lisa Kurczewski
Current American Heart Association/American Stroke Association guidelines for the management of spontaneous intracerebral hemorrhage suggest therapeutic hypothermia (TH) as a salvage therapy in patients with elevated intracranial pressure. Electrolyte disorders may develop at any stage of the cooling process. Such deregulation can place patients at an increased risk for arrhythmias and worsened neurologic outcomes. The impact of TH on serum electrolyte concentration has been described, but electrolyte changes and repletions are yet to be quantified...
December 26, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30575443/factors-predicting-bacterial-infection-in-out-of-hospital-cardiac-arrest-patients-undergoing-target-temperature-management
#7
Seung Mok Ryoo, Seung Joon Yoo, Joon Sung Kim, Gina Yu, Sungmin Jung, Youn-Jung Kim, Chang Hwan Sohn, Won Young Kim
The objective of this study was to determine a risk factor for predicting bacterial infection in patients, who survived out-of-hospital cardiac arrest (OHCA), during target temperature management (TTM). This prospective registry-based retrospective observational study was conducted from November 2010 to October 2017. We measured several biomarkers such as whole blood cell counts, and levels of C-reactive protein and procalcitonin daily during TTM. The primary outcome was bacterial growth in initial blood or sputum cultures...
December 21, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30566035/intraischemic-modest-hypothermia-does-not-prevent-onset-of-locomotor-inactivity-after-transient-forebrain-ischemia-in-rats
#8
Go Nagasaki, Takashi Horiguchi, Yoko Masaki
Although modest hypothermia of 35°C has been demonstrated to provide histological neuroprotection in a rodent model of cerebral ischemia, the long-term behavioral outcome is still not clear. This study was designed to investigate whether modest hypothermia of 35°C provides sustained histological and behavioral neuroprotection following transient forebrain ischemia in rats. Male Sprague-Dawley rats were randomly assigned to one of three groups: sham, control, and modest hypothermia group. Each group contained eight rats...
December 19, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30566033/surface-body-temperature-and-thermoregulation-after-cardiac-arrest
#9
Andrej Markota, Kristijan Skok, Sandra Burja, Jernej Mori
The purpose of our study was to measure surface body temperatures (SBT) and to determine rewarming patterns after surface cooling in adult comatose survivors of cardiac arrest. We performed a prospective study in two phases from April to May 2016 and from December 2017 to March 2018. In the first phase we measured SBT as soon as possible after admission (t0) and 10 minutes later (t10). In the second phase we measured SBT and changes of SBT after local cooling of different regions in the maintenance phase of targeted temperature management...
December 19, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30523732/bleeding-complications-after-cardiac-arrest-and-targeted-temperature-management-a-post-hoc-study-of-the-targeted-temperature-management-trial
#10
Thomas Kander, Susann Ullén, Josef Dankiewicz, Matt P Wise, Ulf Schött, Malin Rundgren
Target Temperature Management (TTM) is standard care following out of hospital cardiac arrest (OHCA). The aim of the study was to evaluate if treatment temperature (33°C or 36°C) or other predefined variables were associated with the occurrence of bleeding in the TTM study. This study is a predefined, post hoc analysis of the TTM trial, a multinational randomized controlled trial comparing treatment at 33°C and 36°C for 24 hours after OHCA with return of spontaneous circulation. Bleeding events from several locations were registered daily...
December 6, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30475159/therapeutic-hypothermia-and-targeted-temperature-management-for-traumatic-arrest-and-surgical-patients
#11
Benjamin N Cragun, Frances Hite Philp, John O'Neill, Matthew R Noorbakhsh, Rachel P Tindall, Allan S Philp, Michael F Ditillo
Therapeutic hypothermia (TH) and targeted temperature management (TTM) have been shown to improve outcomes in survivors of cardiac arrest, but prior research has excluded trauma and postoperative patients. We sought to determine whether TH/TTM is safe in trauma and surgical patients. A retrospective cohort study was conducted at a single level I trauma center reviewing adults presenting as a traumatic arrest or cardiac arrest in the postoperative period with a Glasgow Coma Scale <8 after return of circulation who were treated with either TH or TTM...
November 22, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30457938/therapeutic-hypothermia
#12
W Dalton Dietrich
No abstract text is available yet for this article.
November 20, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30457932/magnetic-resonance-spectroscopy-thermometry-at-3-tesla-importance-of-calibration-measurements
#13
Michael Verius, Florian Frank, Elke Gizewski, Gregor Broessner
To demonstrate the importance of calibration measurements in 3 Tesla proton magnetic resonance (MR) spectroscopy (1 H-MRS) thermometry for human brain temperature estimation for routine clinical applications. In vitro proton MR spectroscopy to obtain calibration constants of the water-chemical shift was conducted at 3 Tesla with a temperature-controlled phantom, containing a pH-buffered aqueous solution of N-acetyl aspartate (NAA), creatine (Cr), methylene protons of Cr (Cr2), dimethyl silapentane sulfonic acid (DSS), and sodium formate (NaFor)...
November 20, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30431392/perspectives-on-temperature-management
#14
Graham Nichol, Kees H Polderman, Hans Friberg, Michael Kurz, Gregory Kapinos
No abstract text is available yet for this article.
November 15, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30427772/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#15
Mary Kay Bader, Stephen A Figueroa, Teresa Wavra, Sarah L Livesay, William D Cahoon, Leslie A Hamilton
No abstract text is available yet for this article.
November 14, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30427769/intra-arrest-induction-of-hypothermia-via-large-volume-ice-cold-saline-for-sudden-cardiac-arrest-the-new-york-city-project-hypothermia-experience
#16
John Freese, Charles B Hall, Elizabeth A Lancet, Rachel Zeig-Owens, Mark Menegus, Norma Keller, Jeffrey Rabrich, Todd L Slesinger, Robert A Silverman, David J Prezant
Therapeutic hypothermia, the standard for post-resuscitation care of out-of-hospital sudden cardiac arrest (SCA), is an area that the most recent resuscitation guidelines note "has not been studied adequately." We conducted a two-phase study examining the role of intra-arrest hypothermia for out-of-hospital SCA, first standardizing the resuscitation and transport of patients to resuscitation centers where post-resuscitation hypothermia was required and then initiating hypothermia during out-of-hospital resuscitation efforts...
November 14, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30412452/therapeutic-hypothermia-in-cardiac-arrest
#17
Marko Noc, Hans Friberg, Chien-Hua Huang, Philip E Empey
No abstract text is available yet for this article.
November 9, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30376419/predictors-of-futility-in-near-hanging-and-therapeutic-hypothermia
#18
Pascal Udekwu, Rhonda Vincent, Debra Petrarca, Meagan Farrell, Sara Roy
Favorable neurologic outcomes have been reported in near-hanging (NH) victims treated with therapeutic hypothermia (TH), but variable methods and small samples sizes limit interpretability. This study examines the relationship between clinical predictors, TH, and outcomes in NH patients. A risk profile was created by examining relationships between variables. Categorical predictors were assessed with chi-square tests and continuous variables were assessed with t-tests. Logistic regression was conducted to evaluate the unique effect of TH...
October 30, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30239278/effects-of-mild-hypothermia-on-cardiac-and-neurological-function-in-piglets-under-pathological-and-physiological-stress-conditions
#19
Wei Yuan, Jun-Yuan Wu, Yong-Zhen Zhao, Jie Li, Jie-Bin Li, Zhen-Hua Li, Chun-Sheng Li
To investigate the different effects of mild hypothermia on pathological and physiological stress conditions in piglets, 30 pigs were randomized into four groups: cardiac arrest and mild hypothermia (CA-MH group), cardiac arrest and normothermia (CA-NH group), non-CA-MH (NCA-MH group), and a sham operation. The same hypothermia intervention was implemented in both CA-MH and NCA-MH groups. The CA-NH group did not undergo therapeutic hypothermia after resuscitation. The hemodynamic parameters were recorded. Cerebral metabolism variables and neurotransmitters in the extracellular fluid were collected through microdialysis tubes...
September 21, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30234442/efficacy-and-safety-of-transnasal-coolstat-cooling-device-to-induce-and-maintain-hypothermia
#20
Fabrizio R Assis, M Emma G Bigelow, Raghuram Chava, Sunjeet Sidhu, Aravindan Kolandaivelu, Henry Halperin, Harikrishna Tandri
Targeted temperature management (TTM) is recommended as a standard of care for postcardiac arrest patients. Current TTM methods have significant limitations to be used in an ambulatory setting. We investigated the efficacy and safety of a novel noninvasive transnasal evaporative cooling device (CoolStat™). Eleven Yorkshire pigs underwent hypothermia therapy using the CoolStat device. CoolStat induces evaporative cooling by blowing dehumidified ambient air over the nasal turbinates in a unidirectional fashion...
September 20, 2018: Therapeutic Hypothermia and Temperature Management
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