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Therapeutic Hypothermia and Temperature Management

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https://www.readbyqxmd.com/read/29135389/cooling-thoughts-over-the-holiday-season
#1
W Dalton Dietrich
No abstract text is available yet for this article.
November 14, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29131707/plasma-neutrophil-gelatinase-associated-lipocalin-measured-immediately-after-restoration-of-spontaneous-circulation-predicts-acute-kidney-injury-in-cardiac-arrest-survivors-who-underwent-therapeutic-hypothermia
#2
Dong Hun Lee, Byung Kook Lee, Yong Soo Cho, Yong Hun Jung, Sung Min Lee, Jung Soo Park, Kyung Woon Jeung
Early diagnosis of acute kidney injury (AKI) after cardiac arrest (CA) is challenging. We aimed to identify the diagnostic and prognostic performance of neutrophil gelatinase-associated lipocalin (NGAL) for AKI and its clinical outcomes. A retrospective observational study, involving adult comatose CA survivors treated with therapeutic hypothermia between May 2013 and December 2016, was conducted. AKI was classified according to the guidelines of Kidney Disease Improving Global Outcomes. NGAL levels were measured after return of spontaneous circulation (ROSC)...
November 13, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29099343/feasibility-study-of-a-novel-high-flow-cold-air-cooling-protocol-of-the-porcine-brain-using-mri-temperature-mapping
#3
Jan Sedlacik, Åsmund Kjørstad, Zsuzsanna Nagy, Jan-Hendrik Buhk, Christoph R Behem, Constantin J Trepte, Jens Fiehler, Fabian Temme
Early, prehospital cooling seeks to reduce and control the body temperature as early as possible to protect the brain and improve patient outcome in cardiac arrest, stroke, and traumatic brain injury. In this study, we investigate the feasibility of localized cooling of the porcine brain by using a novel high-flow cold air protocol, which utilizes the close proximity between the nasal cavity and the brain. Five adult pigs were anesthetized and temperature change was mapped before, during, and after cooling by using the proton resonance frequency method on a 3 T Siemens Magnetom Skyra system...
November 3, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29058556/feasibility-of-a-miniature-esophageal-heat-exchange-device-for-rapid-therapeutic-cooling-in-newborns-preliminary-investigations-in-a-piglet-model
#4
John Dingley, Satomi Okano, Silvia Planas, Elavazhagan Chakkarapani
Therapeutic hypothermia (TH) after neonatal encephalopathy, commonly provided by 72 hours of whole-body cooling using a wrap, limits parents' physical contact with their infants affecting bonding and may not be suitable for encephalopathic preterm infants with fragile skin. Alternative cooling methods are unavailable for this population. We investigated in a neonatal pig model the feasibility of achieving a 3.5°C reduction in rectal temperature (Trectal) similar to clinical TH protocols from 38.5°C (normothermia for pigs) to a target of 35°C ± 0...
October 23, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29058528/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#5
Stephen A Figueroa, Patricia A Blissitt, Sarah Livesay, Teresa Wavra, Mary McKenna Guanci
No abstract text is available yet for this article.
October 23, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29035676/the-molecular-mechanism-and-neuroprotective-effect-of-dihydrocapsaicin-induced-mild-hypothermia-after-cardiopulmonary-resuscitation-in-rats
#6
Xiaopeng Zhong, Xiujuan Wang, Fei Fei, ManCui Zhang, Po Ding, Shiwu Zhang
To investigate the molecular mechanism of dihydrocapsaicin (DHC)-induced mild hypothermia in rats, and to compare its protective effect on the central nervous system with that of a conventional method of inducing hypothermia, 24 healthy male Sprague Dawley rats were randomly divided into four groups based on the following conditions: control group, cardiopulmonary resuscitation (CPR) group, body surface cooling group, and DHC group. Tracheal clipping was used to mimic asphyxia arrest. Rats were assessed for their neurological deficit scores...
October 16, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29027885/therapeutic-hypothermia-in-postcardiac-arrest
#7
Jon Rittenberger, Michael Kurz, Kees H Polderman
No abstract text is available yet for this article.
October 13, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29027874/perspectives-on-temperature-management
#8
Patrick Lyden, Jon Rittenberger, Fred Rincon
No abstract text is available yet for this article.
October 13, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28934599/rewarming-after-severe-accidental-hypothermia-using-the-esophageal-heat-transfer-device-a-case-report
#9
Katarina Katja Primožič, Franci Svenšek, Andrej Markota, Andreja Sinkovič
Patients with severe accidental hypothermia require active rewarming. External rewarming may not be successful in severe hypothermia, and use of invasive techniques is limited to regional centers and is associated with vascular access site and other complications. We present a patient with severe accidental hypothermia who was successfuly rewarmed using a novel esophageal heat transfer device. A 55-year-old male (175 cm, 71 kg) was admitted with the first recorded temperature 23.3°C. Rewarming using renal replacement therapy circuit was unsuccessful because of severe hypotension...
September 21, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28873019/the-effects-of-in-hospital-intravenous-cold-saline-in-postcardiac-arrest-patients-treated-with-targeted-temperature-management
#10
Nissi Suppogu, Gregory A Panza, Sena Kilic, Shreyas Gowdar, Kamala R Kallur, Ramya Jayaraman, Justin Lundbye, Antonio B Fernandez
BACKGROUND: Recent data suggest that rapid infusion of intravenous (IV) cold saline for Targeted Temperature Management (TTM) after cardiac arrest is associated with higher rates of rearrest, pulmonary edema, and hypoxia, with no difference in neurologic outcomes or survival when administered by Emergency Medical Services. We sought to determine the effects of IV cold saline administration in the hospital setting in postcardiac arrest patients to achieve TTM and its effect on clinical parameters and neurologic outcomes...
September 5, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28829674/the-fall-brings-new-heights
#11
W Dalton Dietrich
No abstract text is available yet for this article.
August 22, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28800291/therapeutic-hypothermia-and-targeted-temperature-management-with-or-without-the-cold-stress-response
#12
Patrick M Kochanek, Travis C Jackson
No abstract text is available yet for this article.
September 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28665255/hypothermia-identifies-dynamin-as-a-potential-therapeutic-target-in-experimental-stroke
#13
Jong Youl Kim, Nuri Kim, Jong Eun Lee, Midori A Yenari
Apoptosis is a cell death pathway that is activated in ischemic stroke. The interaction between Fas and its ligand (FasL) initiates a complex pattern of intracellular events involving the recruitment of specific adaptor proteins and the development of apoptosis. We recently reported that dynamin is increased after experimental stroke, and its inhibition improves neurological outcome. Dynamin has been shown to transport Fas from the endoplasmic reticulum to the cell surface where it can be bound by its ligand, FasL...
September 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28467285/hypothalamic-or-extrahypothalamic-modulation-and-targeted-temperature-management-after-brain-injury
#14
Rishabh Charan Choudhary, Xiaofeng Jia
Targeted temperature management (TTM) has been recognized to protect tissue function and positively influence neurological outcomes after brain injury. While shivering during hypothermia nullifies the beneficial effect of TTM, traditionally, antishivering drugs or paralyzing agents have been used to reduce the shivering. The hypothalamic area of the brain helps in controlling cerebral temperature and body temperature through interactions between different brain areas. Thus, modulation of different brain areas either pharmacologically or by electrical stimulation may contribute in TTM; although, very few studies have shown that TTM might be achieved by activation and inhibition of neurons in the hypothalamic region...
September 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27906602/meta-analysis-of-pre-clinical-trials-of-therapeutic-hypothermia-for-intracerebral-hemorrhage
#15
Kara R Melmed, Patrick D Lyden
Therapeutic hypothermia (TH) is a potent neuroprotectant for experimental ischemic stroke, but studies of TH for intracerebral hemorrhage (ICH) are emerging. We systematically reviewed the experimental literature to assess TH efficacy for ICH. We found 18 suitable papers; quality scores were moderately good. Compared with normothermia, TH reduced measures of edema (mean effect size (95% CI) -1.6873 (-2.3640, -1.0106), p < 0.0001) or blood-brain barrier leakage (p < 0.0001) and improved behavioral outcomes (p < 0...
September 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28813633/unique-uses-of-cooling-strategies
#16
Fred Rincon, Morten Bestle, Gregor Brossner, Jitka Vanderpol
No abstract text is available yet for this article.
August 16, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28813616/targeted-temperature-management-in-nursing-care
#17
Justin Lundbye, Heather Hand, Mark Adams, Lindsay Boyd
No abstract text is available yet for this article.
August 16, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28800288/population-based-study-of-the-national-implementation-of-therapeutic-hypothermia-in-infants-with-hypoxic-ischemic-encephalopathy
#18
Juan Arnaez, Alfredo García-Alix, Gemma Arca, Sonia Caserío, Eva Valverde, M Teresa Moral, Isabel Benavente-Fernández, Simón Lubián-López
Data on the incidence of hypoxic-ischemic encephalopathy (HIE) in the first 6 hours of life together with the implementation of therapeutic hypothermia (TH) are relevant to delineate actions to achieve the lowest rates of neonatal mortality, morbidity, and long-term impact on health associated with HIE. This is population-based national survey study, including newborns ≥35 weeks of gestation with moderate-to-severe HIE from all level III neonatal care units, to provide the incidence of HIE for the period 2012-2013, and the implementation of TH up to June 2015 in Spain...
August 11, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28783474/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#19
Sarah Livesay, Stephen A Figueroa, Leslie A Hamilton, William D Cahoon, Patricia A Blissitt
No abstract text is available yet for this article.
August 7, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28731840/clinical-effect-of-rebound-hyperthermia-after-cooling-postcardiac-arrest-a-meta-analysis
#20
Parth Makker, Yumiko Kanei, Deepkia Misra
Rebound hyperthermia (RH) is frequently seen after completion of targeted temperature management (TTM) in comatose survivors of cardiac arrest. However, its clinical significance is not well understood. Previous studies analyzing the association of RH with clinical outcome have reported conflicting results. The purpose of this meta-analysis is to examine the impact of RH after completion of TTM in patients postcardiac arrest. We reviewed six studies that evaluated the incidence of RH (T > 38°C) with documentation of outcome based on the presence of hyperthermia...
July 21, 2017: Therapeutic Hypothermia and Temperature Management
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