journal
MENU ▼
Read by QxMD icon Read
search

Therapeutic Hypothermia and Temperature Management

journal
https://www.readbyqxmd.com/read/30016204/mild-therapeutic-hypothermia-increases-glutathione-levels-in-postcardiac-arrest-patients
#1
Fernanda S Hackenhaar, Tássia M Medeiros, Fernanda M Heemann, Camile S Behling, Camila D Mahl, Cleber Verona, Ana Carolina A Silva, Vanessa Martins Oliveira, Diego F M Riveiro, Silvia R R Vieira, Mara S Benfato
Ischemia-reperfusion (I/R)-induced oxidative stress is one of the main mechanisms of tissue injury after cardiac arrest (CA). A decrease in antioxidant defenses may contribute to I/R injury. The present study aims to investigate the influence of mild therapeutic hypothermia (MTH) on levels of nonenzymatic antioxidants after CA. We investigated antioxidant levels at 6, 12, 36, and 72 hours after CA in central venous blood samples of patients admitted to intensive care. The sample consisted of 31 patients under controlled normothermia (36°C) and 11 patients treated with 24 hours of MTH (33°C)...
July 17, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30016198/implementation-of-targeted-temperature-management-in-a-patient-with-cerebral-arterial-gas-embolism
#2
Se Hyun Oh, Hui Dong Kang, Sang Ku Jung, Sangchun Choi
Cerebral arterial gas embolism (CAGE) shows various manifestations according to the quantity of gas and the brain areas affected. The symptoms range from minor motor weakness, headache, and confusion to disorientation, convulsions, hemiparesis, unconsciousness, and coma. A 46-year-old man was transferred to our emergency department due to altered sensorium. Immediately after a controlled ascent from 33 m of seawater, he complained of shortness of breath and rigid extremities, lapsing into unconsciousness...
July 17, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29993335/successful-therapeutic-hypothermia-in-a-propofol-related-cardiac-arrest-case-a-case-report-and-literature-review
#3
Hamit Yildiz
Targeted temperature management (therapeutic hypothermia) is a treatment method used to prevent potential complications that can develop in relation to the increased temperature in the brain as a result of cardiac arrest. Due to costs and various health policies there is no comprehensive study in the world that has been able to guide the relevant literature on therapeutic hypothermia. We have presented a 25-year-old female patient in our study who developed cardiac arrest after the administration of propofol for sedation before undergoing a diagnostic upper gastroscopy procedure and received a successful therapeutic hypothermia therapy following a resuscitation of 19 minutes...
July 11, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29883298/cool-arrest-results-from-a-pilot-multicenter-prospective-single-arm-observational-trial-to-assess-intravascular-temperature-management-in-the-treatment-of-cardiac-arrest
#4
Kelly N Sawyer, Michael Mooney, Gregory Norris, Thomas Devlin, Justin Lundbye, Pratik B Doshi, Jonathan Kyle Hewett, Alan T Kono, Jesse P Jorgensen, Brian J O'Neil
Targeted temperature management (TTM) is recommended postcardiac arrest. The cooling method with the highest safety and efficacy is unknown. The COOL-ARREST pilot trial aimed to evaluate the safety and efficacy of the most contemporary ZOLL Thermogard XP Intravascular Temperature Management (IVTM) system for providing mild TTM postcardiac arrest. This multicenter, prospective, single-arm, observational pilot trial enrolled patients at eight U.S. hospitals between July 28, 2014, and July 24, 2015. Adult (≥18 years old), out-of-hospital cardiac arrest subjects of presumed cardiac etiology who achieved return of spontaneous circulation (ROSC) were considered for inclusion...
June 8, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29762083/independent-risk-factors-for-the-shivering-occurrence-during-induction-period-in-out-of-hospital-cardiac-arrest-survivors-treated-with-targeted-temperature-management
#5
Youn-Jung Kim, Jin Mi Park, Min Soo Kim, Seung Mok Ryoo, Young Soon Park, Sung Sook Kim, Yeo Ok Kim, Won Young Kim
The occurrence of shivering during the induction period of targeted temperature management (TTM) remains a therapeutic obstacle, which delays the achievement of target temperature. The aim of this study was to identify risk factors leading to shivering during the induction period. We analyzed a prospective cohort of adult out-of-hospital cardiac arrest (OHCA) survivors treated with TTM from January 2015 to June 2017. Patients who developed shivering during the induction period were compared to those who did not...
May 15, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29746218/effect-of-an-innovative-technology-active-warming-and-passive-warming-on-unplanned-hypothermia-during-perioperative-period-a-clinical-trial
#6
Ganime Esra Soysal, Arzu İlçe, Mehmet Hayri Erkol
Patients are at risk for unplanned hypothermia during the perioperative period due to many reasons, including anesthesia, low room temperature, cold intravenous fluid, and blood transfusion. This study was conducted to examine the effect of active and passive warming methods applied in patients during the perioperative period on unplanned hypothermia. This study is a case-control type study. The population of this study is composed of the patients hospitalized in surgical clinic and undergone abdominal region-related operations...
May 10, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29733266/complications-during-therapeutic-hypothermia-after-perinatal-asphyxia-a-comparison-with-trial-data
#7
Carlijn M J Diederen, Frank van Bel, Floris Groenendaal
Complications of therapeutic hypothermia (HT) after perinatal asphyxia of a cohort of infants were compared with complications reported in the Cochrane review. The occurrence during moderate HT of bradycardia, arrhythmia, hypotension, use of inotropes, pulmonary hypertension requiring NO inhalation, air leak syndrome, elevated liver enzymes, necrotizing enterocolitis, sepsis, oliguria, thrombocytopenia, coagulopathy, and electrolyte disturbances was assessed in 168 infants with therapeutic HT following perinatal asphyxia and compared to the incidence of complications published previously in the Cochrane review...
May 7, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29694265/too-hot-to-handle-a-case-report-of-extreme-pyrexia-after-mdma-ingestion
#8
Fritz-Patrick Jahns, Antonine Pineau Mitchell, Georg Auzinger
Hyperpyrexia is a well-documented adverse effect of 3,4-methylenedioxymethamphetamine (MDMA) and is associated with a poor prognosis. There are currently limited published records of patients surviving a pyrexia of or greater than 43°C after MDMA intake. Rapid cooling and multiorgan support in an intensive care setting may offer patients the best chance of recovery. We present the case of a 16-year-old male who was admitted to our tertiary, adult intensive care unit (ICU) for unrecordable pyrexia (>43°C) after self-reported ecstasy intake...
April 25, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29792571/extracorporeal-membrane-oxygenation-and-temperature-management-in-postresuscitation
#9
Hans Friberg, Jonathan Paul, Graham Nichol, Takahiro Nakashima
No abstract text is available yet for this article.
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29742037/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#10
Michelle Hill, William D Cahoon, Mary McKenna Guanci, Patricia A Blissitt, Leslie A Hamilton
No abstract text is available yet for this article.
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29742005/temperature-management-in-neurological-and-neurosurgical-intensive-care-unit
#11
Justin Lundbye, David M Greer, Kees H Polderman, Shoji Yokobori
No abstract text is available yet for this article.
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29742001/targeted-temperature-management-during-the-summer-months
#12
W Dalton Dietrich
No abstract text is available yet for this article.
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29570428/intravascular-cooling-catheter-related-venous-thromboembolism-after-hypothermia-a-case-report-and-review-of-the-literature
#13
Xuan Wang, Brian T Moy, Brett J Hiendlmayr, Felix Krainski, W Lane Duvall, Antonio B Fernandez
Fifty-four year-old man with recent history of myocardial infarction and a percutaneous coronary intervention who suffered a ventricular fibrillation arrest at home. He was resuscitated in the field. His heart rhythm was in atrial fibrillation. The cardiac catheterization showed a patent stent from his previous myocardial infarction and no new occlusions. He subsequently underwent hypothermia protocol using the Alsius CoolGard 3000 Temperature Control System and Icy Catheter. Heparin drip was started for atrial fibrillation 36 hours after catheter insertion and became therapeutic 2 hours before the end of cooling maintenance phase...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29480748/precise-control-of-target-temperature-using-n-6-cyclohexyladenosine-and-real-time-control-of-surface-temperature
#14
Bernard W Laughlin, Isaac R Bailey, Sarah A Rice, Zeinab Barati, Lori K Bogren, Kelly L Drew
Targeted temperature management is standard of care for cardiac arrest and is in clinical trials for stroke. N6 -cyclohexyladenosine (CHA), an A1 adenosine receptor (A1 AR) agonist, inhibits thermogenesis and induces onset of hibernation in hibernating species. Despite promising thermolytic efficacy of CHA, prior work has failed to achieve and maintain a prescribed target core body temperature (Tb ) between 32°C and 34°C for 24 hours. We instrumented Sprague-Dawley rats (n = 19) with indwelling arterial and venous cannulae and a transmitter for monitoring Tb and ECG, then administered CHA via continuous IV infusion or intraperitoneal (IP) injection...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29406818/determination-of-the-target-temperature-required-to-block-increases-in-extracellular-glutamate-levels-during-intraischemic-hypothermia
#15
Sachiko Sato, Yoshimasa Takeda, Ryoichi Mizoue, Hirokazu Kawase, Miki Fushimi, Tomohisa Shimizu, Hiroshi Morimatsu
This study aimed to determine a target temperature for intraischemic hypothermia that can block increases in extracellular glutamate levels. Two groups of 10 rats each formed the normothermia and intraischemic hypothermia groups. Extracellular glutamate levels, the extracellular potential, and the cerebral blood flow were measured at the adjacent site in the right parietal cerebral cortex. Cerebral ischemia was induced by occlusion of the bilateral common carotid arteries and hypotension. In the intraischemic hypothermia group, brain hypothermia was initiated immediately after the onset of membrane potential loss...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29298129/mild-contralesional-hypothermia-reduces-use-of-the-unimpaired-forelimb-in-a-skilled-reaching-task-after-motor-cortex-injury-in-rats
#16
Ana C Klahr, Kelly Fagan, Jasmine R Aziz, Roseleen John, Frederick Colbourne
Therapeutic hypothermia (TH) mitigates neuronal injury in models of ischemic stroke. Although this therapy is meant for injured tissue, most protocols cool the whole body, including the contralesional hemisphere. Neuroplasticity responses within this hemisphere can affect functional outcome. Thus, cooling the contralesional hemisphere serves no clear neuroprotective function and may instead be detrimental. In this study, we cooled the contralesional hemisphere to determine whether this harms behavioral recovery after cortical injury in rats...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29131707/plasma-neutrophil-gelatinase-associated-lipocalin-measured-immediately-after-restoration-of-spontaneous-circulation-predicts-acute-kidney-injury-in-cardiac-arrest-survivors-who-underwent-therapeutic-hypothermia
#17
Dong Hun Lee, Byung Kook Lee, Yong Soo Cho, Yong Hun Jung, Sung Min Lee, Jung Soo Park, Kyung Woon Jeung
Early diagnosis of acute kidney injury (AKI) after cardiac arrest (CA) is challenging. We aimed to identify the diagnostic and prognostic performance of neutrophil gelatinase-associated lipocalin (NGAL) for AKI and its clinical outcomes. A retrospective observational study, involving adult comatose CA survivors treated with therapeutic hypothermia between May 2013 and December 2016, was conducted. AKI was classified according to the guidelines of Kidney Disease Improving Global Outcomes. NGAL levels were measured after return of spontaneous circulation (ROSC)...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29035676/the-molecular-mechanism-and-neuroprotective-effect-of-dihydrocapsaicin-induced-mild-hypothermia-after-cardiopulmonary-resuscitation-in-rats
#18
Xiaopeng Zhong, Xiujuan Wang, Fei Fei, ManCui Zhang, Po Ding, Shiwu Zhang
To investigate the molecular mechanism of dihydrocapsaicin (DHC)-induced mild hypothermia in rats, and to compare its protective effect on the central nervous system with that of a conventional method of inducing hypothermia, 24 healthy male Sprague Dawley rats were randomly divided into four groups based on the following conditions: control group, cardiopulmonary resuscitation (CPR) group, body surface cooling group, and DHC group. Tracheal clipping was used to mimic asphyxia arrest. Rats were assessed for their neurological deficit scores...
June 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29578831/is-it-feasible-and-safe-to-wake-cardiac-arrest-patients-receiving-mild-therapeutic-hypothermia-after-12-hours-to-enable-early-neuro-prognostication-the-therapeutic-hypothermia-and-early-waking-trial-protocol
#19
Noel Watson, Matt Potter, Grigoris Karamasis, Max Damian, Richard Pottinger, Gerald Clesham, Reto Gamma, Rajesh Aggarwal, Jeremy Sayer, Nicholas Robinson, Rohan Jagathesan, Alamgir Kabir, Kare Tang, Paul Kelly, Maria Maccaroni, Ramabhadran Kadayam, Raghu Nalgirkar, Gyanesh Namjoshi, Sali Urovi, Anirudda Pai, Kunal Waghmare, Vincenzo Caruso, James Hampton-Till, Marko Noc, John R Davies, Thomas R Keeble
Mild therapeutic hypothermia (MTH 33°C) post out-of-hospital cardiac arrest (OHCA) is widely accepted as standard of care. However, uncertainty remains around the dose and therapy duration. OHCA patients are usually kept sedated±paralyzed and ventilated for the first 24-36 hours, which allows for targeted temperature management, but makes neurological prognostication challenging. The aim of this study is to investigate the feasibility and safety of assessing the unconscious OHCA patient after 12 hours for early waking/extubation while continuing to provide MTH for 24 hours, and fever prevention for 72 hours by using an intravenous temperature management (IVTM) system and established conscious MTH anti-shiver regimens...
March 26, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29431594/re-feasibility-of-a-miniature-esophageal-heat-exchange-device-for-rapid-therapeutic-cooling-in-newborns-preliminary-investigations-in-a-piglet-model-by-dingley-et-al-ther-hypothermia-temp-manag-2018-8-36-44
#20
Stephanie Slisz, Rogelio Silva, Erik Kulstad
No abstract text is available yet for this article.
March 2018: Therapeutic Hypothermia and Temperature Management
journal
journal
43297
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"