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Therapeutic Hypothermia and Temperature Management

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https://www.readbyqxmd.com/read/28157443/temperature-management-in-the-new-year
#1
W Dalton Dietrich
No abstract text is available yet for this article.
February 3, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28117626/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#2
Stephen A Figueroa, Mary McKenna Guanci, A Blissitt, William D Cahoon
No abstract text is available yet for this article.
January 24, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28106522/clinical-studies-targeting-stroke-and-ischemic-insults
#3
Justin Lundbye, Patrick D Lyden, Kees H Polderman, Stefan Schwab
No abstract text is available yet for this article.
January 20, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28106521/therapeutic-hypothermia-in-postcardiac-arrest
#4
Kees Polderman, Rajesh Dash, Graham Nichol, Nicolas Deye
No abstract text is available yet for this article.
January 20, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28072919/perspectives-on-temperature-management
#5
Graham Nichol, Romer Geocadin, Michael Kurz, Michael Mooney
No abstract text is available yet for this article.
January 10, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27982758/burst-suppression-in-hypothermia-after-cardiac-arrest-because-of-drowning-treated-with-targeted-temperature-management-a-case-report
#6
Tomoya Okazaki, Toru Hifumi, Satoshi Egawa, Hideyuki Hamaya, Natsuyo Shinohara, Shohei Kawamoto, Takuma Iwaki, Kohei Tsukahara, Kenya Kawakita, Takashi Kusaka, Yasuhiro Kuroda
Outcomes of cardiac arrest (CA) because of drowning in children are generally poor, but some reports show that cases with post-CA hypothermia because of drowning exhibit good recovery when treated with targeted temperature management (TTM). However, because electroencephalogram (EEG) findings are not reported in those cases, a complete examination of brain damage has not been performed during TTM. Here we report a case of a 15-month-old boy with post-CA hypothermia recovery after treating with TTM, along with EEG findings...
December 16, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27960070/comparison-of-two-surface-cooling-devices-for-temperature-management-in-a-neurocritical-care-unit
#7
Gurpreet Singh Aujla, Premkumar Nattanmai, Keerthivaas Premkumar, Christopher R Newey
Fever increases mortality and morbidity and length of stay in neurocritically ill patients. Various methods are used in the neuroscience intensive care unit (NSICU) to control fever. Two such methods involve the Arctic Sun hydrogel wraps and the Gaymar cooling wraps. The purpose of our study was to compare these two methods in neurocritical care patients who had temperature >37.5°C for more than three consecutive hours and that was refractory to standard treatments. Data of patients requiring cooling wraps for treatment of hyperthermia at an NSICU at an academic, tertiary referral center were retrospectively reviewed...
December 13, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27906602/meta-analysis-of-pre-clinical-trials-of-therapeutic-hypothermia-for-intracerebral-hemorrhage
#8
Kara R Melmed, Patrick D Lyden
Therapeutic hypothermia (TH) is a potent neuroprotectant for experimental ischemic stroke, but studies of TH for intracerebral hemorrhage (ICH) are emerging. We systematically reviewed the experimental literature to assess TH efficacy for ICH. We found 18 suitable papers; quality scores were moderately good. Compared with normothermia, TH reduced measures of edema (mean effect size (95% CI) -1.6873 (-2.3640, -1.0106), p < 0.0001) or blood-brain barrier leakage (p < 0.0001) and improved behavioral outcomes (p < 0...
December 1, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27906641/time-to-cooling-is-associated-with-resuscitation-outcomes
#9
Robert B Schock, Andreas Janata, W Frank Peacock, Nathan S Deal, Sarathi Kalra, Fritz Sterz
Our purpose was to analyze evidence related to timing of cooling from studies of targeted temperature management (TTM) after return of spontaneous circulation (ROSC) after cardiac arrest and to recommend directions for future therapy optimization. We conducted a preliminary review of studies of both animals and patients treated with post-ROSC TTM and hypothesized that a more rapid cooling strategy in the absence of volume-adding cold infusions would provide improved outcomes in comparison with slower cooling...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27841702/editorial-comment-wrapping-the-year-up
#10
W Dalton Dietrich
No abstract text is available yet for this article.
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27828761/temperature-management-in-neurological-and-neurosurgical-intensive-care-unit
#11
Patrick Lyden, Gretchen M Brophy, Nicolas Deye, Christopher M Horn
No abstract text is available yet for this article.
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27824528/clinical-applications-of-therapeutic-hypothermia
#12
Ryan S Kitagawa, Christian Storm, Hiroshi Nonogi
No abstract text is available yet for this article.
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27809708/clinical-q-a-translating-therapeutic-temperature-management-from-theory-to-practice
#13
Mary Kay Bader, Gretchen M Brophy, Teresa Wavra, Claranne Mathiesen, Mary Kay Bader
No abstract text is available yet for this article.
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27622966/effect-of-hypothermia-and-targeted-temperature-management-on-drug-disposition-and-response-following-cardiac-arrest-a-comprehensive-review-of-preclinical-and-clinical-investigations
#14
Kacey B Anderson, Samuel M Poloyac, Patrick M Kochanek, Philip E Empey
Targeted temperature management (TTM) has been shown to reduce mortality and improve neurological outcomes in out-of-hospital cardiac arrest (CA) patients and in neonates with hypoxic-ischemic encephalopathy (HIE). TTM has also been associated with adverse drug events in the critically ill patient due to its effect on drug pharmacokinetics (PKs) and pharmacodynamics (PDs). We aim to evaluate the current literature on the effect of TTM on drug PKs and PDs following CA. MEDLINE/PubMed databases were searched for publications, which include the MeSH terms hypothermia, drug metabolism, drug transport, P450, critical care, cardiac arrest, hypoxic-ischemic encephalopathy, pharmacokinetics, and pharmacodynamics between July 2006 and October 2015...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27249337/concordance-of-brain-and-core-temperature-in-comatose-patients-after-cardiac-arrest
#15
Patrick J Coppler, Keith A Marill, David O Okonkwo, Lori A Shutter, Cameron Dezfulian, Jon C Rittenberger, Clifton W Callaway, Jonathan Elmer
Comatose patients after cardiac arrest should receive active targeted temperature management (TTM), with a goal core temperature of 32-36°C for at least 24 hours. Small variations in brain temperature may confer or mitigate a substantial degree of neuroprotection, which may be lost at temperatures near 37°C. The purpose of this study was to define the relationship between brain and core temperature after cardiac arrest through direct, simultaneous measurement of both. We placed intracranial monitors in a series of consecutive patients hospitalized for cardiac arrest at a single tertiary care facility within 12 hours of return of spontaneous circulation to guide postcardiac arrest care...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27249179/cerebral-effects-of-targeted-temperature-management-methods-assessed-by-diffusion-weighted-magnetic-resonance-imaging
#16
Anders Morten Grejs, Jakob Gjedsted, Michael Pedersen, Hanne Birke-Sørensen, Andreas Rauff-Mortensen, Kristian Kjær Andersen, Hans Kirkegaard
The aim of this randomized porcine study was to compare surface targeted temperature management (TTM) to endovascular TTM evaluated by cerebral diffusion-weighted magnetic resonance imaging (MRI): apparent diffusion coefficient (ADC), and by intracerebral/intramuscular microdialysis. It is well known that alteration in the temperature affects ADC, but the relationship between cerebral ADC values and the cooling method per se has not been established. Eighteen anesthetized 60-kg female swine were hemodynamically and intracerebrally monitored and subsequently subjected to a baseline MRI...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27213805/intracranial-pressure-increases-during-rewarming-period-after-mild-therapeutic-hypothermia-in-postcardiac-arrest-patients
#17
Hiromichi Naito, Eiji Isotani, Clifton W Callaway, Shingo Hagioka, Naoki Morimoto
Elevation of intracranial pressure (ICP) may worsen brain injury and neurological outcome. Studies on the use of therapeutic hypothermia (TH) for traumatic brain injury suggests that rapid rewarming from TH is associated with elevated ICP and poorer outcomes. However, few studies describe the time course of ICP changes during TH/rewarming after cardiac arrest (CA). In this study, we observed the changes in ICP during mild TH and rewarming after CA. Secondarily, we examined whether ICP is related to outcome...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27167667/use-of-normothermic-default-humidifier-settings-causes-excessive-humidification-of-respiratory-gases-during-therapeutic-hypothermia
#18
Shoichiro Tanaka, Sachiko Iwata, Masahiro Kinoshita, Kennosuke Tsuda, Sayaka Sakai, Mamoru Saikusa, Ryota Shindo, Eimei Harada, Junichiro Okada, Tadashi Hisano, Hiroshi Kanda, Yasuki Maeno, Yuko Araki, Kazuo Ushijima, Teruo Sakamoto, Yushiro Yamashita, Osuke Iwata
Adult patients frequently suffer from serious respiratory complications during therapeutic hypothermia. During therapeutic hypothermia, respiratory gases are humidified close to saturated vapor at 37°C (44 mg/L) despite that saturated vapor reduces considerably depending on temperature reduction. Condensation may cause serious adverse events, such as bronchial edema, mucosal dysfunction, and ventilator-associated pneumonia during cooling. To determine clinical variables associated with inadequate humidification of respiratory gases during cooling, humidity of inspiratory gases was measured in 42 cumulative newborn infants who underwent therapeutic hypothermia...
December 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27875660/successful-use-of-targeted-temperature-management-after-repair-of-myocardial-rupture-from-blunt-chest-trauma-a-case-report
#19
Wook-Jin Choi, Yun Seok Kim, Jung Seok Hong, Jeong Won Kim
Targeted temperature management (TTM) improves survival and neurological outcome after nontraumatic cardiac arrest. However, TTM is not used widely after traumatic cardiac arrest because of concerns that it might exacerbate bleeding. We report the use of postarrest TTM after repair of blunt myocardial rupture. A 48-year-old man was admitted after being rescued from a major traffic accident by the local emergency service. Focused sonography showed pericardial fluid without cardiac tamponade. Computed tomography showed a large hematoma in the anterior mediastinum associated with hemopericardium...
November 22, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27860555/time-to-awakening-is-often-delayed-in-patients-who-receive-targeted-temperature-management-after-cardiac-arrest
#20
Katie Zanyk-McLean, Kelly N Sawyer, Ryan Paternoster, Rebekah Shievitz, William Devlin, Robert Swor
Post cardiac arrest, neuroprognostication remains a complex and clinically challenging issue for critical care providers. For this reason, our primary objective in this study was to determine the frequency of survival and favorable neurological outcomes in post-cardiac arrest patients with delayed time to awakening. To assess whether early withdrawal of care may adversely impact survival, we also sought to describe the time to withdrawal of care of non-surviving patients. We performed a retrospective study of patients resuscitated after cardiac arrest in two large academic community hospitals...
November 18, 2016: Therapeutic Hypothermia and Temperature Management
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