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Journal of Adolescent and Young Adult Oncology

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https://www.readbyqxmd.com/read/28541785/long-term-follow-up-consultation-after-childhood-cancer-in-the-rh%C3%A3-ne-alpes-region-of-france-feedback-from-adult-survivors-and-their-general-practitioners
#1
Claire Berger, Léonie Casagranda, Cécile Faure-Conter, Claire Freycon, Florentina Isfan, Aurélie Robles, Béatrice Trombert-Paviot, Isabelle Guichard, Isabelle Durieu, Pascal Cathebras
PURPOSE: We evaluated the satisfaction of adult survivors of childhood cancers and their general practitioners (GP) after a long-term consultation. METHODS: The first Long-term Follow-up Study in Oncology (SALTO1) is a prospective cohort study of survivors of childhood cancers (except leukemia) diagnosed between 1987 and 1992 in the Rhône-Alpes and Auvergne regions of France. Of the 481 patients eligible for the study, 150 participated in a long-term consultation with a pediatric oncologist and an internist, after which survivors and their GPs received long-term plans and recommendations based on consultation findings...
May 25, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28537818/adolescent-and-young-adult-patients-with-cancer-perceptions-of-care
#2
Kayla N LaRosa, Marilyn Stern, Jennifer Bleck, Courtney Lynn, Janella Hudson, Damon R Reed, Gwendolyn P Quinn, Kristine A Donovan
BACKGROUND: Adolescent and young adults with cancer (AYACs) face unique medical, psychosocial, and supportive care needs. The purpose of this study was to identify AYACs perceptions and expectations of cancer care services on and off treatment. METHODS: Semistructured interviews were conducted with 23 AYACs aged 19-38 years (13 on and 10 off treatment), who were receiving care at a comprehensive cancer center. Verbatim transcripts were created from audiotaped interviews and hand coded using inductive content analysis methodology...
May 24, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28530506/racial-differences-in-20-year-cardiovascular-mortality-risk-among-childhood-and-young-adult-cancer-survivors
#3
Amy M Berkman, Abenaa M Brewster, Lee W Jones, Jun Yu, J Jack Lee, S Andrew Peng, Abigail Crocker, Joann L Ater, Susan C Gilchrist
PURPOSE: Whether cardiovascular disease (CVD) risk differs according to race and cancer type among survivors of childhood or young adulthood cancers is unknown. METHODS: Data from the years 1973-2011 were analyzed using the Surveillance, Epidemiology, and End Results (SEER) registries. Cases were categorized by ICD-0-3/WHO 2008 Adolescent and Young Adult classification. CVD death was determined by ICD-10 codes for diseases of the heart, atherosclerosis, cerebrovascular diseases, or other diseases of the arteries...
May 22, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28530479/from-the-editor-in-chief-s-desk
#4
Leonard S Sender
No abstract text is available yet for this article.
May 22, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28525286/cancer-patient-experience-in-the-teenage-young-adult-population-key-issues-and-trends-over-time-an-analysis-of-the-united-kingdom-national-cancer-patient-experience-surveys-2010-2014
#5
Caroline L Furness, Lesley Smith, Eva Morris, Caroline Brocklehurst, Sasha Daly, Rachael E Hough
Improving outcomes for teenagers and young adults (TYA) with cancer is a key element of the national cancer strategy in England. Recognition of the unique needs of this group has led to the development of recommendations for specific models of care and delivery of this care through the provision of dedicated clinical units in principal treatment centers (PTCs) across the United Kingdom. The aim of this study was to understand the current cancer patient experience for this patient group. We aimed to determine whether treatment experience is influenced by place of treatment and whether it has changed over time using patient-reported data from national cancer patient experience surveys...
May 19, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28498727/good-prognosis-went-badly-fulminant-evolution-of-a-29-year-old-patient-with-verrucous-carcinoma-of-the-cervix
#6
Rodica M Anghel, Oana G Trifanescu, Radu I Mitrica, Fabiana G Curea, Inga Botnariuc, Catalin G Herghelegiu, Cristina M Orlov, Silvia M Ilie
Verrucous carcinoma (VC) is a very rare variant of squamous cell carcinoma of the cervix, difficult to point out in histology because of its benign appearance. We present the case of a 29-year-old woman with a locally advanced cervical VC who underwent radiotherapy followed by radical hysterectomy. After local relapse and despite pelvic exenteration, her condition deteriorated. Treatment of choice in VC is surgery, because of the risk of anaplastic transformation under irradiation, raising the chances of distant spread and converting this rather benign-like type of cancer to an aggressive cancer...
May 12, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28459598/practices-and-attitudes-regarding-women-undergoing-fertility-preservation-a-survey-of-the-national-physicians-cooperative
#7
Pietro Bortoletto, Rafael Confino, Brigid M Smith, Teresa K Woodruff, Mary Ellen Pavone
PURPOSE: To describe physician attitudes and variations in oncofertility treatment strategies. METHODS: An exploratory online survey administered between December 1, 2014 and January 27, 2015 to 185 members of the National Physicians Cooperative (NPC). RESULTS: Twenty-eight percent (52 of 185) of NPC members responded to the online survey. Fifty percent of respondents were obstetrician-gynecologists working largely in academic medical centers...
May 1, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28430009/evaluating-questionnaires-used-to-assess-self-reported-physical-activity-and-psychosocial-outcomes-among-survivors-of-adolescent-and-young-adult-cancer-a-cognitive-interview-study
#8
Amanda Wurz, Jennifer Brunet
Physical activity is increasingly being studied as a way to improve psychosocial outcomes (e.g., quality of life, self-efficacy, physical self-perceptions, self-esteem, body image, posttraumatic growth) among survivors of adolescent and young adult (AYA) cancer. Assessing levels of and associations between self-reported physical activity and psychosocial outcomes requires clear, appropriate, and relevant questionnaires. To explore how survivors of AYA cancer interpreted and responded to the following eight published questionnaires: Leisure Time Exercise Questionnaire, Exercise Self-Efficacy Scale, Physical Self-Description Questionnaire, Rosenberg Global Self-Esteem Scale, Multidimensional Body-Self Relations Questionnaire, Posttraumatic Growth Inventory, Functional Assessment of Cancer Therapy-General (FACT-G), RAND 36-Item Health Survey 1...
April 21, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28422548/epidemiological-profile-and-treatment-outcomes-in-young-adults-19-29-years-of-age-treated-for-cancer-in-a-tertiary-hospital-in-s%C3%A3-o-paulo-brazil
#9
Victor Hugo Fonseca de Jesus, Taynan Nunes Ribeiro, Ludmilla T Domingos Chinen, Vanessa Alves, Maria Paula Curado, Marcello Ferretti Fanelli
BACKGROUND: Worldwide, the incidence of cancer in young adults (20-39 years) is increasing, and represents an important cause of mortality in this age group. A retrospective study was undertaken to provide information that may lead to improved treatment outcomes. METHODS: Epidemiological, clinicopathological, treatment, and survival information were retrieved from the electronic database registry of a tertiary referral hospital in São Paulo, Brazil for patients 19-29 years of age diagnosed with cancer between January 2007 and December 2012...
April 19, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28380309/using-appearance-based-messages-to-increase-sun-protection-in-adolescent-young-adult-cancer-survivors-a-pilot-study-of-ultraviolet-light-photography
#10
Christopher J Recklitis, Jennifer Bakan, Andrew E Werchniak, Heike Mahler
Despite risk for secondary skin cancers, many adolescent and young adult (AYA) cancer survivors do not practice recommended sun protection (SP). Ultraviolet light photography (UVP), which demonstrates the negative impact of sun exposure on physical appearance, has been shown to increase SP in community AYA samples. This study of 58 AYA cancer survivors demonstrates that UVP is acceptable and not distressing to this population. Follow-up data on 23 AYAs demonstrated that those given UVP significantly improve their SP behaviors, while those receiving standard educational materials do not...
April 5, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28338407/optimizing-a-retention-strategy-with-young-people-for-brightlight-a-longitudinal-cohort-study-examining-the-value-of-specialist-cancer-care-for-young-people
#11
Rachel M Taylor, Natasha Aslam, Sarah Lea, Jeremy S Whelan, Lorna A Fern
PURPOSE: To maximize retention of participants in a longitudinal cohort study, we sought to understand young peoples' views about barriers and facilitators to continuing study participation. METHODS: Ten young people with a previous cancer diagnosis aged 15-24 participated in a 1 day workshop. The workshop used participatory methodology consisting of three exercises as follows: role play/scene setting; force field analysis of research participation in small groups; and focus group discussion...
March 24, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28338384/methotrexate-induced-neurotoxicity-in-hispanic-adolescents-with-high-risk-acute-leukemia-a-case-series
#12
Lisa Giordano, Oyinade Akinyede, Nidhi Bhatt, Dipti Dighe, Asneha Iqbal
Intrathecal methotrexate (IT MTX) and high-dose intravenous methotrexate (HD MTX) are important components of treatment in high-risk acute leukemia. We describe five Hispanic adolescents with high-risk acute leukemia at our institution who experienced MTX-induced neurotoxicity. All patients were eventually rechallenged with MTX. Two of the five patients had a second episode of neurotoxicity, but all patients recovered. Further studies should be performed to determine whether Hispanic patients are more susceptible to MTX neurotoxicity...
March 24, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28263668/monocytes-macrophages-and-osteoclasts-in-osteosarcoma
#13
Fergal C Kelleher, Hazel O'Sullivan
Macrophages appear to have a fundamental role in the pathogenesis of osteosarcoma. These highly diverse plastic cells are subdivided into classical or inflammatory macrophages known as M1 and alternative macrophages, which decrease inflammation and are reparative, called M2. Although primary and metastatic osteosarcomas are infiltrated with M2 macrophages, targeting the M1 macrophages with the immune adjuvant muramyl tripeptide phosphatidyl ethanolamine (MTP-PE) has been the greatest recent therapeutic advance in osteosarcoma...
March 6, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28080182/multi-professional-perspectives-on-adolescent-and-young-adult-oncology-across-europe-an-e-delphi-survey
#14
Simon A Pini, Faith Gibson, Lorna A Fern, Sue J Morgan, Robert S Phillips, Dan P Stark
The aims of this article are to describe the ongoing development of adolescent and young adult (AYA) cancer services within the European Union (EU), and to develop consensus on key areas within the field. This survey used an e-Delphi design. An initial survey was distributed via email to professionals working in Europe. A snowball sampling technique was used to promote distribution. Consensus was sought over three rounds from October 2012 to April 2015. Consensus was defined as >80% agreement ("agree" or "strongly agree")...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27841952/prescriptions-of-antidepressants-to-survivors-of-cancer-in-childhood-adolescence-and-young-adulthood-a-population-based-study
#15
Inga Maria Johannsdottir, Øystein Karlstad, Jon H Loge, Sophie D Fosså, Cecilie Kiserud, Svetlana Skurtveit
PURPOSE: Survivors of cancer may experience higher rates of psychological problems requiring pharmacological interventions than age-matched controls from the general population. This study compares prescription rates of antidepressants in survivors of cancer, diagnosed in childhood, adolescence, or early adulthood, to the rate in age- and gender-matched controls from the Norwegian population. METHODS: Antidepressants prescribed to 5341 cancer survivors, diagnosed ≤25 years during 1965-2000, were studied in a population-based cohort by linking data from the following nationwide registries: the Population Registry of Norway, the Cancer Registry of Norway, and the Norwegian Prescription Database...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27828715/validation-of-three-previously-developed-short-forms-of-the-beck-depression-inventory-for-youth-a-replication
#16
Jaime E Blackmon, Cori Liptak, Christopher J Recklitis
Three previously developed short forms of the Beck Depression Inventory-Youth (BDI-Y) were validated against the standard 20-item BDI-Y; 168 adolescent survivors completed the standard and short-form versions of the BDI-Y. The short forms were evaluated for internal consistency and compared with the standard BDI-Y using correlation coefficients and receiver operating characteristic curve analyses. The three short forms had good internal consistency (α > 0.85), high correlations with the total BDI-Y scale (r > 0...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27792462/what-a-pain-the-impact-of-physical-symptoms-and-health-management-on-pursuit-of-personal-goals-among-adolescents-with-cancer
#17
Lisa A Schwartz, Lauren D Brumley
PURPOSE: This study examined health-related hindrance (HRH) of personal goals among adolescents receiving treatment for cancer and healthy peers. METHODS: Adolescents and parents completed measures of demographics and psychosocial variables. Adolescents reported on their HRH, measured by ratings of the impact of pain, fatigue, other physical symptoms, and doing things to manage their health on self-identified personal goals. Disease-related information was abstracted from patient charts...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27779446/a-comparison-of-extremity-thrombosis-rates-in-adolescent-and-young-adult-versus-younger-pediatric-oncology-patients-at-a-children-s-hospital
#18
James D Cooper, Aimee G Costello, Peter H Shaw
PURPOSE: To examine whether the rates of thrombosis in children (≤14 years of age) and adolescent/young adult (AYA) patients (15-22 years of age) with cancer is different. METHODS: We retrospectively studied the rates of thrombosis in children and AYA patients at the Children's Hospital of Pittsburgh during the years 2002-2010, using the tumor registry database. This list was then divided into two groups based on age at diagnosis. A review of ICD-9 codes from hospital billing records was then performed to identify patients who carried diagnoses of cancer (140...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27779442/risk-benefit-analysis-of-pediatric-inspired-versus-hyperfractionated-cyclophosphamide-vincristine-doxorubicin-and-dexamethasone-protocols-for-acute-lymphoblastic-leukemia-in-adolescents-and-young-adults
#19
Gregory F Guzauskas, Kathleen F Villa, Geertrui F Vanhove, Vicki L Fisher, David L Veenstra
PURPOSE: To estimate the risk-benefit trade-off of a pediatric-inspired regimen versus hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (hyper-CVAD) for first-line treatment of adolescents/young adult (AYA; ages 16-39 years) patients with Philadelphia-negative acute lymphoblastic leukemia. METHODS: Patient outcomes were simulated using a 6-state Markov model, including complete response (CR), no CR, first relapse, second CR, second relapse, and death...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27768513/memories-of-parent-behaviors-and-adult-attachment-in-childhood-cancer-survivors
#20
Vicky Lehmann, Mariët Hagedoorn, Cynthia A Gerhardt, Madelaine C Keim, Lory Guthrie, Robbert Sanderman, Marrit A Tuinman
PURPOSE: Childhood cancer is stressful for the entire family. Preoccupation and anxiety surrounding the child's illness may result in parents of children with cancer being overprotective or less emotionally responsive toward their children. Such parenting in response to a negative life event like childhood cancer may cause survivors to be more insecurely attached than healthy peers, which could have downstream effects on survivors' romantic relationships later in life. Therefore, we examined survivors' perspectives on parent behaviors, adult attachment, and marital status among adult survivors of childhood cancer relative to controls...
March 2017: Journal of Adolescent and Young Adult Oncology
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