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Journal of Adolescent and Young Adult Oncology

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https://www.readbyqxmd.com/read/29446693/hyperparathyroidism-mimicking-metastatic-bone-disease-a-case-report-and-review-of-literature
#1
Monica Gupta, Lalita Singhal, Akshay Kumar
Multiple osteolytic lesions are usually associated with metastatic involvement of the bone; however, metabolic bone diseases should also be included in the differential diagnosis. In this study, we describe a case of primary hyperparathyroidism (PHPT) with multiple osteolytic lesions that was diagnosed initially as having metastatic bone involvement. The laboratory results showed hypercalcemia and raised alkaline phosphatase along with fibrosis in the bone marrow biopsy with no increase in tumor markers and normal serum protein electrophoresis...
February 15, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29437492/the-experience-of-adolescents-and-young-adults-treated-for-cancer-in-an-adult-setting-a-review-of-the-literature
#2
Steve Marshall, Anne Grinyer, Mark Limmer
The purpose of this review is to explore the literature on the experience of adolescents and young adults (AYAs) having cancer treatment in an adult setting, rather than on a specialist adolescent cancer unit. The integrative review method was used to explore the current literature. Primary research on the topic was located systematically and then synthesized into a thematic narrative. The experience of AYAs undergoing treatment in an adult setting was generally negative. This can be attributed to three themes: feeling isolated in the adult setting; the lack of empathy from staff working in the adult setting; and the inappropriateness of the adult environment for this age group...
February 13, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29425060/measuring-development-of-adolescent-and-young-adult-cancer-patients-an-integrative-review-of-available-instruments
#3
Cynthia J Bell, Ryan A Bell, Brad Zebrack, Ikuko Kato, Alyssa Morse, Scott C Borinstein
Adolescents and young adults (AYAs) 15-39 years old face unique challenges during cancer treatment as developmental and social needs are often disrupted to achieve cure. Developmentally appropriate supportive care for AYAs across the cancer trajectory is needed. The purpose of this review is to identify and describe instruments that measure AYA development across physical, psychological, and social domains, commenting on the instruments' psychometric properties and usefulness in clinical practice and research...
February 9, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29412770/two-cases-of-hepatoblastoma-in-young-adults
#4
Karel de Bree, Anneke M Westermann, Heinz-Josef Klümpen, Joanne Verheij, Saffire S K S Phoa, Matthijs Oomen, Thomas M van Gulik
Adult hepatoblastoma (AHB) is a rare liver tumor with a poor prognosis in adolescents and adults. This contrasts with hepatoblastoma in children and is not fully understood. Here we describe two adolescents with AHB who were treated in our hospital. Adolescents are likely to receive less intensive chemotherapy protocols and are treated in hospitals with less experience in pediatric oncology, resulting in poor outcome. More research is necessary for optimal treatment of AHB in adolescents. Adolescents with AHB should be referred to hospitals experienced in pediatric oncology and receive intensive chemotherapy, followed by hemihepatectomy...
February 7, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29406798/successful-treatment-of-adolescents-and-young-adults-with-philadelphia-negative-acute-lymphoblastic-leukemia-by-novel-l-asparaginase-intensified-induction-therapy-and-cord-blood-transplantation-a-single-center-decade-report
#5
Akira Kojima, Kazunari Yamada, Koichi Kajiwara, Yuichi Takeuchi, Marina Matsui, Masao Tsukada, Kanichi Iwama, Yasuji Kozai, Hideki Kodo
A novel induction therapy, including intensive L-asparaginase, was designed in 2007 for patients aged <45 years with Philadelphia-negative acute lymphoblastic leukemia (ALL). We analyzed seven de novo cases and one case of recurrence who received this treatment. The median age was 21 years (range: 16-35 years). Four patients had T-ALL and the others had B-ALL. All the patients achieved complete remission and proceeded to cord blood transplantation. In the median 72-month follow-up, there were no cases of observed mortality or recurrence...
February 6, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29394126/biopsychosocial-distress-in-young-adult-oncology-patients-examining-sex-differences-in-sources-of-high-distress-and-requests-for-assistance
#6
Elaine Wheat Dawson, Karen Clark, Richard Obenchain, Matthew J Loscalzo, Jeanelle Folbrecht
PURPOSE: This study examines biopsychosocial problem-related distress and requests for assistance with male and female young adult patients by applying a large-scale analysis among individuals diagnosed with a variety of cancers. METHODS: A retrospective study was conducted involving 630 patients of ages 18-39 treated for cancer at City of Hope between 2009 and 2014. Patients were asked to complete a biopsychosocial problem-related distress touch-screen instrument before treatment as part of their routine clinical care...
February 2, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29373051/self-perceived-physical-attractiveness-in-relation-to-scars-among-adolescent-and-young-adult-cancer-survivors-a-population-based-study
#7
Maria Olsson, Karin Enskär, Gunnar Steineck, Ulrica Wilderäng, Marianne Jarfelt
OBJECTIVE: Cancer treatment may result in various effects that last long after treatment has been concluded. The purpose of this study was to explore to what extent scars affect adolescents and young adults postcancer treatment. METHODS: In this population-based study, a study-specific questionnaire was developed by a method used in several previous investigations carried out by our research group, Clinical Cancer Epidemiology. Question development involved expert validation by professionals from oncology units, midwives, epidemiologists, and statisticians...
January 26, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29373040/australian-adolescents-and-young-adults-trends-in-cancer-incidence-mortality-and-survival-over-three-decades
#8
David M Roder, Allison Warr, Pandora Patterson, Kimberley R Allison
PURPOSE: Cancer is a significant health concern for adolescents and young adults (AYAs; aged 15-24 years). Monitoring population-level changes in incidence, mortality, and survival is complicated by the lack of published data presenting statistics separately for AYAs. This study synthesizes and reviews data on AYA cancers in Australia, including trends in incidence and mortality. METHODS: National data were extracted for 1980-2012, primarily from the Australian Cancer Database and Australian National Mortality Database...
January 26, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29364765/young-adult-female-cancer-survivors-concerns-about-future-children-s-health-and-genetic-risk
#9
Nirupa Jaya Raghunathan, Catherine Benedict, Bridgette Thom, Danielle Novetsky Friedman, Joanne Frankel Kelvin
As young adult female cancer survivors (aged 18-35) make family-building decisions, understanding the specific nature of their concerns is important. We evaluated survivors' concerns about potential health risks to future children including genetic susceptibility for cancer with an internet-based survey study (N = 187). Sixty-five percent reported concern about passing on a genetic cancer risk to their children, and scores did not vary regardless of association with cancer at high risk for genetic transmission...
January 24, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29356588/experiences-of-care-of-adolescents-and-young-adults-with-cancer-in-australia
#10
Victoria White, Gemma Skaczkowski, Kate Thompson, Helen Bibby, Michael Coory, Ross Pinkerton, Wayne Nicholls, Lisa M Orme, Rachel Conyers, Marianne B Phillips, Michael Osborn, Rosemary Harrup, Antoinette Anazodo
PURPOSE: To examine the care experiences of Australian Adolescents and Young Adults (AYAs) with cancer during a period when youth cancer services (YCS) were developing across the country. METHODS: A cross-sectional, self-report survey completed by 207 recently diagnosed AYAs with cancer, recruited from the population-based cancer registries of Australia's two most populous states. AYAs were 15 to 24 years old when diagnosed with any form of cancer (except melanoma <3 mm or stage I/II)...
January 22, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29346023/fertility-preservation-in-pediatric-oncology-patients-new-perspectives
#11
Chiara Gertosio, Mariasole Magistrali, Paola Musso, Cristina Meazza, Mauro Bozzola
Over the past 30 years, advances in antineoplastic treatment led to a significant increase in the survival of patients with childhood cancer. In Europe and the United States, 82% of children, adolescents, and young adults survive 5 years from the cancer diagnosis and the majority achieves long-term survival into adulthood. The impact of cancer therapy on fertility is related to the age of the patient and to the duration, dose/intensity, and type of treatment. Exposure to chemotherapy or to radiation to gonads or pituitary brings long-term complications of cancer-directed therapies that include effects on reproductive capacity...
January 18, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29346008/follow-up-care-provider-preferences-of-adolescent-and-young-adult-cancer-survivors
#12
Joemy M Ramsay, Karely Mann, Sapna Kaul, Eduardo R Zamora, Rochelle R Smits-Seemann, Anne C Kirchhoff
PURPOSE: To explore the experiences and perspectives of adolescent and young adult (AYA) cancer survivors regarding patient-provider relationships and their preferences surrounding type of healthcare provider for follow-up care. METHODS: We recruited AYA cancer survivors who were diagnosed between the ages of 15 and 39 using the Utah Cancer Registry. Twenty-eight survivors participated in six focus groups held between March and May of 2015 in Salt Lake City and St...
January 18, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29336666/educational-needs-of-health-professionals-caring-for-adolescents-and-young-adults-with-cancer
#13
Natalie K Bradford, Rebecca Greenslade, Rachel M Edwards, Rebekah Orford, Jane Roach, Roslyn Henney
BACKGROUND: Young people with cancer have distinct clinical and psychosocial needs during and after cancer treatment. However, as adolescent and young adult (AYA) cancer is rare, and only recently recognized as specialty, health professionals may not have the skills, competence, and confidence to meet the needs of the young patient with cancer. The aim of this study was to identify the learning needs of health professionals providing cancer care to adolescents and young adults before and following the introduction of a state-wide AYA cancer education program...
January 16, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29336661/cancer-related-genetic-testing-and-personalized-medicine-for-adolescents-a-narrative-review-of-impact-and-understanding
#14
Janine Vetsch, Claire E Wakefield, Meera Warby, Katherine Tucker, Pandora Patterson, Brittany C McGill, Alison Metcalfe, Richard J Cohn, Joanna E Fardell
Genetic testing is becoming increasingly available for adolescents who are undergoing cancer treatment or at risk of cancer predisposition syndromes. With this narrative review, we aimed to synthesize the evidence on psychosocial outcomes and adolescents' understanding of genetic testing-thus far, an underresearched topic. Both psychological benefits and harms of predictive testing were reported in adolescents from high-risk families. Harms were mainly related to cancer-specific distress and increased worries...
January 16, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29336660/current-practice-patterns-surrounding-fertility-concerns-in-stage-i-seminoma-patients-survey-of-united-states-radiation-oncologists
#15
Carl M Post, Aditya Jain, Catherine Degnin, Yiyi Chen, Mike Craycraft, Arthur Y Hung, Jerry J Jaboin, Charles R Thomas, Timur Mitin
PURPOSE: Patients with testicular seminoma may face fertility issues because of their underlying disease as well as treatments they undergo. The current patterns of practice among U.S. radiation oncologists aimed at assessing and preserving fertility in patients with Stage I seminoma are unknown. METHODS: We surveyed practicing U.S. radiation oncologists via an Institutional Review Board-approved online questionnaire. Respondents' characteristics and perceived patient infertility rates were analyzed for association with treatment recommendations...
January 16, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29319398/sexual-health-issues-for-the-young-adult-with-cancer-an-international-symposium-held-during-the-first-global-adolescents-and-young-adults-cancer-congress-edinburgh-united-kingdom
#16
Laura Mitchell, Jeremy Lewin, Julia Dirks, Kate Wang, Seline Tam, Anne Katz, Beth McCann, Kirk Lo, Valerie Laurence, Christine Rousset-Jablonski, Abha A Gupta
Sexual health is an important consideration for young adults with cancer; however, oncology healthcare providers are often not equipped with strategies to approach these problems in a systematic way. To address this gap in adolescents and young adults (AYA) care, a one-day international Sexual Health Symposium was held before the Global AYA Cancer Congress (Edinburgh, December 2016). The goals of the symposium were to (1) provide a forum, where international AYA experts had the opportunity to share their knowledge regarding AYA sexual health and (2) develop a guideline for healthcare professionals to screen for and intervene on sexual health issues...
January 10, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29315007/improving-fertility-preservation-in-breast-cancer-patients
#17
Katarzyna Pogoda, Agnieszka Jagiełło-Gruszfeld, Anna Niwińska, Maria Litwiniuk, Jakub Rzepka, Zbigniew Nowecki
No abstract text is available yet for this article.
January 9, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29303620/patient-reported-outcomes-in-psychological-treatment-for-an-adolescent-oncology-patient-a-case-report
#18
Nicole M Racine, Lucie Lafay-Cousin, Fiona Schulte
This case study describes the use of patient-reported outcome (PRO) in conjunction with psychosocial treatment for an adolescent oncology patient presenting with comorbid mental health difficulties. A nine-session evidence-based cognitive-behavioral treatment was implemented and PROs were used to document progress. Results demonstrated an overall pattern of increase in health-related quality of life and decrease in mood and anxiety symptoms as treatment progressed, with increases occurring after disease recurrence...
January 5, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29298121/re-racial-differences-in-20-year-cardiovascular-mortality-risk-among-childhood-and-young-adult-cancer-survivors-by-berkman-et-al-j-adolesc-young-adult-oncol-2017-6-3-414-21
#19
Daniela Fernanda Valiente, Rodrigo Alexander Coico, Roger Vladimir Araujo-Castillo
No abstract text is available yet for this article.
January 3, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29298112/antineoplastic-agents-and-in-fertility-informing-patients-to-improve-decisions
#20
Cristina Silva, Ana Teresa Almeida-Santos, Cláudia Melo, Ana Cristina Ribeiro Rama
PURPOSE: Infertility is a potential adverse effect of cancer treatment, and future fertility is an important issue for cancer patients. In Portugal, the Centre for Fertility Preservation of CHUC, EPE, conducted a project to develop and disseminate oncofertility information resources. In this study, we report the results of the specific component of this program, which intended to produce information resources that promote patients' awareness of the subject and to support decisions concerning fertility preservation...
January 3, 2018: Journal of Adolescent and Young Adult Oncology
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