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Neurology Research International

Cansu Köseoğlu Toksoy, Cem Bölük, Ülkü Türk Börü, Seydahmet Akın, Abdullah Yasir Yılmaz, Sanem Coşkun Duman, Mustafa Taşdemir
Background: This study aims to determine the stroke prevalence in Akçakoca which is a rural area in Turkey. Methods: The study was designed as a cross-sectional, door-to-door survey. The stroke questionnaire was completed by a trained team in the presence of the participants according to their answers. Based on the screenings, patients who had been diagnosed with stroke previously were reexamined by a neurologist and determined the prevalence values, risk factors, and stroke types...
2018: Neurology Research International
Jisu Elsa Jacob, Gopakumar Kuttappan Nair, Thomas Iype, Ajith Cherian
EEG analysis in the field of neurology is customarily done using frequency domain methods like fast Fourier transform. A complex biomedical signal such as EEG is best analysed using a time-frequency algorithm. Wavelet decomposition based analysis is a relatively novel area in EEG analysis and for extracting its subbands. This work aims at exploring the use of discrete wavelet transform for extracting EEG subbands in encephalopathy. The subband energies were then calculated and given as feature sets to SVM classifier for identifying cases of encephalopathy from normal healthy subjects...
2018: Neurology Research International
Marcelo de Lima Oliveira, Angela Macedo Salinet, Ricardo de Carvalho Nogueira, Alessandro Rodrigo Belon, Wellingson Silva Paiva, Brasil Chian Ping Jeng, Manoel Jacobsen Teixeira, Edson Bor-Seng-Shu
Background: This study aimed to analyse cerebral autoregulation (CA) during induction and treatment of intracranial hypertension (ICH) in an experimental model. Materials and Methods: Landrace and Duroc piglets were divided into mild and severe ICH groups. Four or seven millilitres of saline solution was infused into paediatric bladder catheter inserted in the parietal lobe (balloon inflation). After 1.5 h, a 3% saline solution was infused via venous catheter, and 30 min later, the bladder catheter balloon was deflated (surgery)...
2018: Neurology Research International
Jisu Elsa Jacob, Ajith Cherian, K Gopakumar, Thomas Iype, Doris George Yohannan, K P Divya
Chaotic analysis is a relatively novel area in the study of physiological signals. Chaotic features of electroencephalogram have been analyzed in various disease states like epilepsy, Alzheimer's disease, sleep disorders, and depression. All these diseases have primary involvement of the brain. Our study examines the chaotic parameters in metabolic encephalopathy, where the brain functions are involved secondary to a metabolic disturbance. Our analysis clearly showed significant lower values for chaotic parameters, correlation dimension, and largest Lyapunov exponent for EEG in patients with metabolic encephalopathy compared to normal EEG...
2018: Neurology Research International
Mohammad-Amin Khajezadeh, Gholamreza Zamani, Bobak Moazzami, Zahra Nagahi, Mahdie Mousavi-Torshizi, Vahid Ziaee
Objective: Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system. In the present study, we aimed to assess neuropsychiatric manifestations in juvenile-onset systemic lupus erythematosus (JSLE) in Iran. Methods: One hundred and forty-six pediatric onset patients with SLE who had registered in our pediatric rheumatology database were evaluated prospectively and cross sectionally within 2013-2015...
2018: Neurology Research International
Monsicha Ngampoopun, Piradee Suwanpakdee, Nattapon Jaisupa, Charcrin Nabangchang
Nonconvulsive status epilepticus (NCSE) and acute repetitive seizures (ARS) are associated with significant morbidity and mortality. Due to the lack of randomized-controlled trials of intravenous antiepileptic drugs (AEDs) in these conditions, trials of a new generation of AEDs in this aspect are needed. A prospective interventional study was conducted in children under 18 years of age with NCSE or ARS who either had contraindication to or were refractory to first-line AEDs and received intravenous lacosamide...
2018: Neurology Research International
Urai Kummarg, Siriorn Sindhu, Sombat Muengtaweepongsa
Background: Intravenous recombinant tissue plasminogen activator (i.v. rt-PA) is the milestone treatment for patients with acute ischemic stroke. Stroke Fast Track (SFT) facilitates time reduction, guarantees safety, and promotes good clinical outcomes in i.v. rt-PA treatment. Nursing case management is a healthcare service providing clinical benefits in many specific diseases. The knowledge about the efficacy of a nurse case management for Stroke Fast Track is limited. We aim to study the effect of nurse case management on clinical outcomes in patients with acute ischemic stroke involving intravenous recombinant tissue plasminogen activator (i...
2018: Neurology Research International
Jéssica Lopes de Souza, Aline Scardoeli Faiola, Carmen Silvia Molleis Galego Miziara, Maria Luiza Giraldes de Manreza
Objective: To evaluate the perceived social stigma of people with epilepsy with regard to the question of employability. Methods: A structured questionnaire was given to two groups of people with chronic diseases: those with epilepsy (study group) and those with heart disease (control group). The questions concerned employability. Results: Having epilepsy was more strongly associated with higher unemployment rates ( p < 0.0001); job layoffs ( p = 0...
2018: Neurology Research International
Hilda Nouri Hosseini, Mohammad Reza Mohammadi, Mohsen Aarabi, Narges Mohammadi, Mohammad Jafar Golalipour
Background and Objective: Corpus callosum (CC), the main white matter cable which connects two hemispheres of brain, is important in special procedures such as stereotaxic surgeries vary in size, in different populations. Determination of possible size differences in ethnical groups has special values. Patients and Methods: The size of the CC on midsagittal view was determined in 76 normal male subjects using MRI of brain hemispheres in northern Iran. The size of rostrum, body, splenium, length, and height of CC was measured for each subject...
2018: Neurology Research International
Nattaphol Uransilp, Pannawat Chaiyawatthanananthn, Sombat Muengtaweepongsa
Backgrounds: Stroke is the leading cause of death and long-term disability. Oxidative stress is elevated during occurrence of acute ischemic stroke (AIS). Soluble LOX-1 (sLOX-1) and NO are used as biomarkers for vascular oxidative stress that can reflect stabilization of atherosclerotic plaque. Previous study showed that simvastatin can reduce oxidative stress and LOX-1 expression. Objectives: To evaluate neurological outcomes and serum sLOX-1 and NO levels in patients with AIS treatment with low dose 10 mg/day and high dose 40 mg/day of simvastatin...
2018: Neurology Research International
Mathieu Nemerimana, Margaret Njambi Chege, Eunice Ajode Odhiambo
Background: Many of the nongenetic causal risk factors of intellectual disability (ID) can be prevented if they are identified early. There is paucity on information regarding potential risk factors associated with this condition in Kenya. This study aimed to establish risk factors associated with severity of nongenetic intellectual disability (ID) among children presenting with this condition at Kenyatta National Hospital (KNH). Methods: A hospital-based cross-sectional study was conducted over the period between March and June 2017 in pediatric and child/youth mental health departments of Kenyatta National Hospital (KNH), Kenya...
2018: Neurology Research International
Julianne Vermeer, Amanda McIntyre, Shannon Janzen, Danielle Rice, Laura Allen, David Ure, Robert Teasell
Poststroke depression has been shown to affect rehabilitation progress. This study evaluated patients after stroke who actively participated in a home-based rehabilitation program to determine variables that correlated with depressive symptoms in this population. A retrospective review of patients who were provided rehabilitation by Community Stroke Rehabilitation Team clinicians between January 1, 2009, and September 30, 2015, was completed. Logistic regression analysis was conducted to determine which demographic and outcome variables (Functional Independence Measure [FIM™] and Reintegration to Normal Living Index [RNLI]) were independently associated with depressive symptoms, as defined by Patient Health Questionnaire (PHQ-9) scores...
2018: Neurology Research International
Auwal Abdullahi
Background: Constraint-induced movement therapy (CIMT) is effective in improving motor outcomes after stroke. However, its existing protocols are resource-intensive and difficult to implement. The aim of this study is to design an easier CIMT protocol using number of repetitions of shaping practice. Method: The study design was randomized controlled trial. Participants within 4 weeks after stroke were recruited at Murtala Muhammad Specialist Hospital. They were randomly assigned to groups A, B, C, and D...
2018: Neurology Research International
Anna Caroline Marques Braga, Anabela Pinto, Susana Pinto, Mamede de Carvalho
Introduction: The efficacy of cardiopulmonary exercise testing (CPET) to determining exercise intensity has not been established in Amyotrophic Lateral Sclerosis (ALS). We studied this intervention. Methods: We included 48 ALS patients randomized in 2 groups: G1 ( n = 24), exercise intensity leveled by CPET; G2 ( n = 24), standard care limited by fatigue, during 6 months. ALS functional scale (ALSFRS-R) and forced vital capacity (FVC) were performed every 3 months; CPET was done at admission ( T 1) and 6 months later ( T 2)...
2018: Neurology Research International
Mohammed H Alanazy, Rima B Barakeh, Alanood Asiri, Maha F Edrees, Ahmad R Abuzinadah, Bandar N Aljafen, Taim Muayqil
Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset (50...
2018: Neurology Research International
Berhanu Boru Bifftu, Bewket Tadesse Tiruneh, Mengistu Mekonnen Kelkay, Nestanet Habte Bayu, Abebe Woldesellassie Tewolde, Wubet Worku Takele, Mehammed Adem Getnet, Abere Woretaw Azagew
Background: The characteristics of epilepsy such as the episodic nature of impairment of consciousness and motor control, psychomotor comorbidity, seizure frequency, and side effects of antiepileptic drugs impact negatively on the physical safety of the patients. Physical injuries such as burn, fracture, dental loss, and hemorrhage affect the quality of patients' life to the extent of death. Thus, the main purpose of this study was to assess the prevalence of physical injury and associated factors among people with epilepsy...
2017: Neurology Research International
Chaiyaporn Yuksen, Yuwares Sittichanbuncha, Jayanton Patumanond, Sombat Muengtaweepongsa, Kasamon Aramvanitch, Amornrat Supamas, Kittisak Sawanyawisuth
Patients with mild head injuries, a GCS of 13-15, are at risk for intracranial hemorrhage. Clinical decision is needed to weigh between risks of intracranial hemorrhage and costs of the CT scan of the brain particularly those who are equivocal. This study aimed to find predictors for intracranial hemorrhage in patients with mild head injuries with a moderate risk of intracranial hemorrhage. We defined moderate risk of mild head injury as a GCS score of 13-15 accompanied by at least one symptom such as headache, vomiting, or amnesia or with alcohol intoxication...
2017: Neurology Research International
Radish Kumar Balasubramanium, Thejaswi Dodderi, Jayashree S Bhat
Objectives: It is well established that the brainstem regulates the act of swallow. However, the role of cortex and its influence on swallowing are still a question. Hence, the present study aimed to investigate if cerebral hemispheric laterality controls swallow activity. Methods: Thirty normal right handed participants were subjected to time test of swallow using 100 ml of water. Dual paradigm was used to investigate hemispheric laterality for swallowing which involved listening to the speech or music stimuli presented binaurally while swallowing...
2017: Neurology Research International
Gleb Makshakov, Evgeniy Magonov, Natalia Totolyan, Vladimir Nazarov, Sergey Lapin, Alexandra Mazing, Elena Verbitskaya, Tatiana Trofimova, Vladimir Krasnov, Maria Shumilina, Alexander Skoromets, Evgeniy Evdoshenko
Leptomeningeal contrast enhancement (LMCE) on magnetic resonance imaging (MRI) is a newly recognized possible biomarker in multiple sclerosis (MS), associated with MS progression and cortical atrophy. In this study, we aimed to assess the prevalence of LMCE foci and their impact on neurodegeneration and disability. Materials. 54 patients with MS were included in the study. LMCE were detected with a 3 Tesla scanner on postcontrast fluid-attenuated inversion-recovery (FLAIR) sequence. Expanded Disability Status Scale (EDSS) score, number of relapses during 5 years from MS onset, and number of contrast-enhancing lesions on T1 weighted MRI were counted...
2017: Neurology Research International
Jittima Saengsuwan, Pathitta Suangpho, Somsak Tiamkao
Stroke is a global burden. It is not known whether patients who are most at risk of stroke (recurrent stroke or recurrent transient ischaemic attack) have enough knowledge of stroke risk factors and warning signs. The aim of this study was to assess the knowledge of stroke risk factors and warning signs in this high-risk population. We performed a cross-sectional questionnaire-based study of patients with recurrent stroke or recurrent TIA admitted to Srinagarind Hospital and Khon Kaen Hospital, Thailand. A total of 140 patients were included in the study (age 65...
2017: Neurology Research International
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