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Neurology Research International

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https://www.readbyqxmd.com/read/29375913/seizure-related-injuries-among-people-with-epilepsy-at-the-outpatient-department-of-the-university-of-gondar-hospital-northwest-ethiopia-cross-sectional-institutional-based-study
#1
Berhanu Boru Bifftu, Bewket Tadesse Tiruneh, Mengistu Mekonnen Kelkay, Nestanet Habte Bayu, Abebe Woldesellassie Tewolde, Wubet Worku Takele, Mehammed Adem Getnet, Abere Woretaw Azagew
Background: The characteristics of epilepsy such as the episodic nature of impairment of consciousness and motor control, psychomotor comorbidity, seizure frequency, and side effects of antiepileptic drugs impact negatively on the physical safety of the patients. Physical injuries such as burn, fracture, dental loss, and hemorrhage affect the quality of patients' life to the extent of death. Thus, the main purpose of this study was to assess the prevalence of physical injury and associated factors among people with epilepsy...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29359046/clinical-factors-predictive-for-intracranial-hemorrhage-in-mild-head-injury
#2
Chaiyaporn Yuksen, Yuwares Sittichanbuncha, Jayanton Patumanond, Sombat Muengtaweepongsa, Kasamon Aramvanitch, Amornrat Supamas, Kittisak Sawanyawisuth
Patients with mild head injuries, a GCS of 13-15, are at risk for intracranial hemorrhage. Clinical decision is needed to weigh between risks of intracranial hemorrhage and costs of the CT scan of the brain particularly those who are equivocal. This study aimed to find predictors for intracranial hemorrhage in patients with mild head injuries with a moderate risk of intracranial hemorrhage. We defined moderate risk of mild head injury as a GCS score of 13-15 accompanied by at least one symptom such as headache, vomiting, or amnesia or with alcohol intoxication...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29318044/does-cerebral-hemispheric-laterality-control-swallow-performance
#3
Radish Kumar Balasubramanium, Thejaswi Dodderi, Jayashree S Bhat
Objectives: It is well established that the brainstem regulates the act of swallow. However, the role of cortex and its influence on swallowing are still a question. Hence, the present study aimed to investigate if cerebral hemispheric laterality controls swallow activity. Methods: Thirty normal right handed participants were subjected to time test of swallow using 100 ml of water. Dual paradigm was used to investigate hemispheric laterality for swallowing which involved listening to the speech or music stimuli presented binaurally while swallowing...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29291134/leptomeningeal-contrast-enhancement-is-associated-with-disability-progression-and-grey-matter-atrophy-in-multiple-sclerosis
#4
Gleb Makshakov, Evgeniy Magonov, Natalia Totolyan, Vladimir Nazarov, Sergey Lapin, Alexandra Mazing, Elena Verbitskaya, Tatiana Trofimova, Vladimir Krasnov, Maria Shumilina, Alexander Skoromets, Evgeniy Evdoshenko
Leptomeningeal contrast enhancement (LMCE) on magnetic resonance imaging (MRI) is a newly recognized possible biomarker in multiple sclerosis (MS), associated with MS progression and cortical atrophy. In this study, we aimed to assess the prevalence of LMCE foci and their impact on neurodegeneration and disability. Materials. 54 patients with MS were included in the study. LMCE were detected with a 3 Tesla scanner on postcontrast fluid-attenuated inversion-recovery (FLAIR) sequence. Expanded Disability Status Scale (EDSS) score, number of relapses during 5 years from MS onset, and number of contrast-enhancing lesions on T1 weighted MRI were counted...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29130000/knowledge-of-stroke-risk-factors-and-warning-signs-in-patients-with-recurrent-stroke-or-recurrent-transient-ischaemic-attack-in-thailand
#5
Jittima Saengsuwan, Pathitta Suangpho, Somsak Tiamkao
Stroke is a global burden. It is not known whether patients who are most at risk of stroke (recurrent stroke or recurrent transient ischaemic attack) have enough knowledge of stroke risk factors and warning signs. The aim of this study was to assess the knowledge of stroke risk factors and warning signs in this high-risk population. We performed a cross-sectional questionnaire-based study of patients with recurrent stroke or recurrent TIA admitted to Srinagarind Hospital and Khon Kaen Hospital, Thailand. A total of 140 patients were included in the study (age 65...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29123923/root-securing-and-brain-fortifying-liquid-upregulates-caveolin-1-in-cell-model-with-alzheimer-s-disease-through-inhibiting-tau-phosphorylation
#6
Depei Yuan, Chuhua Zeng, Qianfeng Chen, Fengjie Wang, Lin Yuan, Yaoqian Zhu, Ziyang Shu, Ning Chen
In order to explore the effect of root-securing and brain-fortifying Liquid- (RSBFL-) mediated caveolin-1 (CAV-1) on phosphorylation of Tau protein and to uncover underlying mechanisms of RSBFL for the prevention and treatment of Alzheimer's disease (AD), hippocampal neurons isolated from neonatal SD rats and cultured in DMEM-F12 medium were induced by exogenous Aβ1-42 to establish a cell model with AD. Meanwhile, pEGFP-C1-CAV1 and CAV1-shRNA plasmids were transfected into hippocampal neurons for CAV-1 overexpression and silence, respectively...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29075532/spinal-nerves-schwannomas-experience-on-367-cases-historic-overview-on-how-clinical-radiological-and-surgical-practices-have-changed-over-a-course-of-60-years
#7
Jacopo Lenzi, Giulio Anichini, Alessandro Landi, Alfonso Piciocchi, Emiliano Passacantilli, Francesca Pedace, Roberto Delfini, Antonio Santoro
BACKGROUND: Spinal schwannomas are common benign spinal tumors. Their treatment has significantly evolved over the years, and preserving neurological functions has become one of the main treatment goals together with tumor resection. STUDY DESIGN AND AIMS: Retrospective review focused on clinical assessment, treatment techniques, and outcomes. METHODS: A retrospective study on our surgical series was performed. Clinical and operative data were analyzed...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28831311/corrigendum-to-effect-of-chronic-morphine-consumption-on-synaptic-plasticity-of-rat-s-hippocampus-a-transmission-electron-microscopy-study
#8
Mohammad Hassan Heidari, Abdollah Amini, Zohreh Bahrami, Ali Shahriari, Abolfazl Movafagh, Reihane Heidari
[This corrects the article DOI: 10.1155/2013/290414.].
2017: Neurology Research International
https://www.readbyqxmd.com/read/28713592/clinicodemographic-profile-of-children-with-seizures-in-a-tertiary-care-hospital-a-cross-sectional-observational-study
#9
Nagendra Chaudhary, Murli Manohar Gupta, Sandeep Shrestha, Santosh Pathak, Om Prakash Kurmi, B D Bhatia, K N Agarwal
Seizures are one of the common causes for hospital admissions in children with significant mortality and morbidity. This study was conducted to study the prevalence and clinicodemographic profile of children with seizures in a tertiary care hospital of western Nepal. This prospective cross-sectional study conducted over a period of 2 years included all admitted children (2 months-16 years) with seizures. Among 4962 admitted children, seizures were present in 3.4% (n = 168) of children, with male preponderance...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28630769/comparing-the-expression-of-genes-related-to-serotonin-5-ht-in-c57bl-6j-mice-and-humans-based-on-data-available-at-the-allen-mouse-brain-atlas-and-allen-human-brain-atlas
#10
C A Acevedo-Triana, L A León, F P Cardenas
Brain atlases are tools based on comprehensive studies used to locate biological characteristics (structures, connections, proteins, and gene expression) in different regions of the brain. These atlases have been disseminated to the point where tools have been created to store, manage, and share the information they contain. This study used the data published by the Allen Mouse Brain Atlas (2004) for mice (C57BL/6J) and Allen Human Brain Atlas (2010) for humans (6 donors) to compare the expression of serotonin-related genes...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28491476/increased-intracranial-pressure-in-the-setting-of-enterovirus-and-other-viral-meningitides
#11
Jules C Beal
Increased intracranial pressure due to viral meningitis has not been widely discussed in the literature, although associations with Varicella and rarely Enterovirus have been described. Patients with increased intracranial pressure and cerebrospinal fluid analysis suggestive of a viral process are sometimes classified as having atypical idiopathic intracranial hypertension (IIH). However, a diagnosis of IIH requires normal cerebrospinal fluid, and therefore in these cases an infection with secondary intracranial hypertension may be a more likely diagnosis...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28484650/efficacy-of-keyhole-approach-to-carpal-tunnel-syndrome-under-ambulatory-strategy
#12
Rodrigo Ramos-Zúñiga, César J García-Mercado, Iván Segura-Durán, Luis A Zepeda-Gutiérrez
The carpal tunnel syndrome is one of the most common entrapment neuropathies found in humans. Currently, the gold standard is surgical treatment using different modalities. The minimally invasive strategy with high resolution capacity and less morbidity is still a challenge. Methods. Prospective nonrandomised clinical trial in which a minimally invasive microsurgical approach was used following the keyhole principle in 55 consecutive patients and 65 hands under local anesthesia and ambulatory strategy. They were evaluated with stringent inclusion criteria with the Levine severity and functional status scale and with a 2-year follow-up...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28392943/report-from-a-survey-of-parents-regarding-the-use-of-cannabidiol-medicinal-cannabis-in-mexican-children-with-refractory-epilepsy
#13
Carlos G Aguirre-Velázquez
Structured online surveys were used to explore the experiences of the parents of children with refractory epilepsy using medicinal cannabis in Mexico during September 2016. The surveys, which were completed in full, were reviewed, and 53 cases of children aged between 9 months and 18 years were identified. Of these, 43 cases (82%) were from Mexico and 10 (18%) were from Latin American countries. Of the 43 Mexican cases, the diagnoses were as follows: 20 cases (47%) had Lennox-Gastaut syndrome (LGS); 13 cases (30%) had unspecified refractory epilepsy (URE); 8 cases (19%) had West syndrome (WS); 1 case (2%) had Doose syndrome (DS); and 1 case (2%) had Ohtahara syndrome (OS)...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28210506/combined-supplementation-of-choline-and-docosahexaenoic-acid-during-pregnancy-enhances-neurodevelopment-of-fetal-hippocampus
#14
Huban Thomas Rajarethnem, Kumar Megur Ramakrishna Bhat, Malsawmzuali Jc, Siva Kumar Gopalkrishnan, Ramesh Babu Mugundhu Gopalram, Kiranmai Sesappa Rai
Choline is an essential nutrient for humans which plays an important role in structural integrity and signaling functions. Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid, highly enriched in cell membranes of the brain. Dietary intake of choline or DHA alone by pregnant mothers directly affects fetal brain development and function. But no studies show the efficacy of combined supplementation of choline and DHA on fetal neurodevelopment. The aim of the present study was to analyze fetal neurodevelopment on combined supplementation of pregnant dams with choline and DHA...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28133547/accumulation-of-%C3%AE-synuclein-in-cerebellar-purkinje-cells-of-diabetic-rats-and-its-potential-relationship-with-inflammation-and-oxidative-stress-markers
#15
Volkan Solmaz, Hatice Köse Özlece, Hüseyin Avni Eroglu, Hüseyin Aktuğ, Oytun Erbaş, Dilek Taşkıran
Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar accumulation of α-synuclein in streptozotocin- (STZ-) induced diabetes model in rats. Methods. Twelve rats were included in the study. Diabetes (n = 6) was induced with a single intraperitoneal injection of streptozotocin (STZ, 60 mg/kg). Diabetes was verified after 48 h by measuring blood glucose levels...
2017: Neurology Research International
https://www.readbyqxmd.com/read/28116158/remotely-assessing-symptoms-of-parkinson-s-disease-using-videoconferencing-a-feasibility-study
#16
Tereza Stillerova, Jacki Liddle, Louise Gustafsson, Robyn Lamont, Peter Silburn
Purpose. To evaluate the feasibility of assessing a person's symptoms of Parkinson's disease (PD) in their home using the videoconferencing technology they already possess, without a home visit. Method. Eleven participants with PD completed the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) face-to-face and then via videoconferencing within a two-week period. Participants used free software and the computers and webcams available at their home to complete the videoconference assessment with a clinical rater scoring remotely...
2016: Neurology Research International
https://www.readbyqxmd.com/read/28116157/protective-effect-of-ppar%C3%AE-agonists-on-cerebellar-tissues-oxidative-damage-in-hypothyroid-rats
#17
Yousef Baghcheghi, Farimah Beheshti, Hossein Salmani, Mohammad Soukhtanloo, Mahmoud Hosseini
The aim of the current study was to investigate the effects of peroxisome proliferator-activated receptor gamma (PPARγ) agonists on cerebellar tissues oxidative damage in hypothyroid rats. The animals included seven groups: group I (control), the animals received drinking water; group II, the animals received 0.05% propylthiouracil (PTU) in drinking water; besides PTU, the animals in groups III, IV, V, VI, and VII, were injected with 20 mg/kg vitamin E (Vit E), 10 or 20 mg/kg pioglitazone, and 2 or 4 mg/kg rosiglitazone, respectively...
2016: Neurology Research International
https://www.readbyqxmd.com/read/28018676/increased-serum-levels-of-tumor-necrosis-factor-alpha-resistin-and-visfatin-in-the-children-with-autism-spectrum-disorders-a-case-control-study
#18
Mohammad Ali Ghaffari, Elham Mousavinejad, Forough Riahi, Masoumeh Mousavinejad, Mohammad Reza Afsharmanesh
Background. Autism spectrum disorders (ASDs) are complex disorders where the pathogenesis is not fully understood. Several proinflammatory and immunoinflammatory disturbances have been observed in the etiology of ASD. There is, however, limited knowledge on variations of adipokines in ASD. The present study aimed to analyze the serum levels of resistin, visfatin, and tumor necrosis factor-alpha (TNF-α) in children with ASD in relation to body weight, gender, and ASD severity level. Method. In total, 30 children with ASD (mean age: 7...
2016: Neurology Research International
https://www.readbyqxmd.com/read/28018675/description-of-ictal-hfo-mapping-in-patients-with-both-temporal-and-extratemporal-seizure-focus
#19
Juan G Ochoa, Walter G Rusyniak
Objective. Review presurgical use of ictal HFO mapping to detect ictal activation areas with dual seizure focus in both the temporal and extratemporal cortex. Methods. Review of consecutive patients admitted to the University of South Alabama Epilepsy Monitoring Unit (SouthCEP) between January 2014 and October 2015, with suspected temporal lobe epilepsy and intracranial electrode recording. Ictal HFO localization was displayed in 3D reconstructed brain images using the patient's own coregistered magnetic resonance imaging (MRI) and computed tomography (CT) with the implanted electrodes...
2016: Neurology Research International
https://www.readbyqxmd.com/read/27800180/cognitive-function-in-parkinson-s-disease-patients-with-and-without-anxiety
#20
K A Ehgoetz Martens, J Y Y Szeto, A J Muller, J M Hall, M Gilat, C C Walton, S J G Lewis
Research on the implications of anxiety in Parkinson's disease (PD) has been neglected despite its prevalence in nearly 50% of patients and its negative impact on quality of life. Previous reports have noted that neuropsychiatric symptoms impair cognitive performance in PD patients; however, to date, no study has directly compared PD patients with and without anxiety to examine the impact of anxiety on cognitive impairments in PD. This study compared cognitive performance across 50 PD participants with and without anxiety (17 PDA+; 33 PDA-), who underwent neurological and neuropsychological assessment...
2016: Neurology Research International
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