journal
MENU ▼
Read by QxMD icon Read
search

Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders

journal
https://www.readbyqxmd.com/read/30013411/influence-of-hla-b27-subtypes-on-ankylosing-spondylitis-phenotype-comment-on-the-article-by-akassou-et-al
#1
Sasan Fallahi
No abstract text is available yet for this article.
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/30013410/patient-discomfort-and-resident-confidence-after-knee-intra-articular-injection-simulation-training-a-randomized-control-trial-study
#2
Adae O Amoako, George Ga Pujalte, Neha Kaushik, Timothy Riley
Teaching primary care providers how to perform musculoskeletal procedures has become increasingly important as more and more patients with orthopedic conditions present in primary care clinics. This study aims to evaluate whether targeted simulation model training in residency can increase residents' comfort level in performing intra-articular knee injections and decrease the pain of the procedure, as reported by patients injected. Residents were randomized into intervention and control groups. The comfort level of the residents as well as the pain levels from the procedures, as reported by patients, was recorded...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29977118/safety-and-predictive-factors-of-short-term-efficacy-of-a-single-injection-of-mannitol-modified-cross-linked-hyaluronic-acid-in-patients-with-trapeziometacarpal-osteoarthritis-results-of-a-multicentre-prospective-open-label-pilot-study-instinct-trial
#3
Jérémy Dauvissat, Christophe Rizzo, Henri Lellouche, Jérôme Porterie, Sylvie Melac-Ducamp, Vincent Locquet, Vincent Travers, Bernard Maillet, Thierry Conrozier
Purpose: To assess safety and search predictive factors of efficacy of a single intra-articular injection of a mannitol-modified hyaluronic acid (HA) viscosupplement, in patients having trapeziometacarpal (TMC) osteoarthritis (OA). Methods: Patients with symptomatic TMC OA, not adequately relieved by analgesic therapy and/or by the use of a thumb splint, were included in a 3-month prospective multicentre open-label trial. All underwent plain radiographs with the Kapandji incidences allowing the Dell radiological grade assessment (1-4)...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29977117/short-term-outcomes-in-treatment-of-knee-osteoarthritis-with-4-bone-marrow-concentrate-injections
#4
Brent Shaw, Marc Darrow, Armen Derian
Background: Preliminary research suggests that bone marrow concentrate (BMC), which contains mesenchymal stem cells and platelets, is a promising treatment for knee osteoarthritis. The aim of this study was to build on this preliminary research by reporting the short-term progress of 15 patients (20 knees) with knee osteoarthritis through 4 BMC treatments. Methods: Patients underwent four sequential BMC treatments with mean injection times of 13.80 days after the first treatment, 21...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29899668/retrocalcaneal-bursitis-precedes-or-accompanies-achilles-tendon-enthesitis-in-the-early-phase-of-rheumatoid-arthritis
#5
Takeshi Suzuki, Yuka Hidaka, Yu Seri
The consecutive reports and stored images of ultrasound examinations for 100 symptomatic ankles of 74 patients with rheumatoid arthritis (RA) were reviewed for the presence or absence of retrocalcaneal bursitis (RCB) and Achilles tendon enthesitis (ATE). The ankles were classified into 4 categories based on the presence or absence of RCB or ATE. The number of RCB(-)/ATE(-), RCB(+)/ATE(-), RCB(+)/ATE(+), and RCB(-)/ATE(+) ankles was 62, 16, 12, and 10, respectively. When classifying patients into early RA and established RA, the percentage of RCB(-)/ATE(+) ankles with early RA was significantly lower than that with established RA ( P  = ...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29780263/a-pooled-analysis-of-two-multicenter-randomized-controlled-trials-of-a-single-intra-articular-injection-of-gel-200-for-treatment-of-osteoarthritis-of-the-knee
#6
Junko Takamura, Takayuki Seo, Vibeke Strand
Background and Objective: To perform an integrated analysis of 2 randomized controlled trials (RCTs) to assess the efficacy and safety of a single intra-articular injection of Gel-200 compared with phosphate buffered saline (PBS) for treatment of osteoarthritis of the knee. Methods: Data from the intention-to-treat (ITT) populations of both RCTs were pooled for this integrated analysis. Mean changes from baseline in Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain subscores were assessed using a longitudinal model; treatment differences were compared between intra-articular Gel-200 and PBS injections...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29511361/late-presentation-of-infected-silicone-granulomas-in-the-lower-limb
#7
Zita M Jessop, Matthew Welck, Emily Zinser, Nicholas Garlick, Susan Hopkins
Introduction: Dermal fillers are used for multiple cosmetic indications including gluteal and thigh augmentation. Complications, although infrequent, are increasing due to the dramatic growth of dermal filler use. Our aim was to describe how the complication of infected silicone granulomas can present following lower limb augmentation. Methods: Two cases presented with pain, oedema, and erythema at the site of previous silicone filler injection, following a considerable delay after the last injection (range 4-7 years)...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29467586/an-observational-1-month-trial-on-the-efficacy-and-safety-of-promerim-for-improving-knee-joint
#8
Bekir Eray Kilinc, Yunus Oc, Gungor Alibakan, Emre Bilgin, Muharrem Kanar, Osman Tugrul Eren
Objective: This study was conducted to evaluate the efficacy and tolerability of the oral intake of promerim in the elimination of acute pain and discomfort associated with knee osteoarthritis (OA). Methods: Single-center, 1-month, prospective, observational clinical trial. A total of 92 patients not older than 70 years were included. Patients were offered to use 720-mg promerim for the first 15 days after admission after breakfast and then 360 mg for the second 15 days...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29434479/osteoarthritis-and-the-complement-cascade
#9
REVIEW
Sandeep Silawal, Jakob Triebel, Thomas Bertsch, Gundula Schulze-Tanzil
Accumulating evidence demonstrates that complement activation is involved in the pathogenesis of osteoarthritis (OA). However, the intimate complement regulation and cross talk with other signaling pathways in joint-associated tissues remain incompletely understood. Recent insights are summarized and discussed here, to put together a more comprehensive picture of complement involvement in OA pathogenesis. Complement is regulated by several catabolic and inflammatory mediators playing a key role in OA. It seems to be involved in many processes observed during OA development and progression, such as extracellular cartilage matrix (ECM) degradation, chondrocyte and synoviocyte inflammatory responses, cell lysis, synovitis, disbalanced bone remodeling, osteophyte formation, and stem cell recruitment, as well as cartilage angiogenesis...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29371786/total-knee-arthroplasty-does-day-of-surgery-matter
#10
Azeem Tariq Malik, Shahid Khan, Arif Ali, Syed Hamza Mufarrih, Shahryar Noordin
Introduction: There has been an influx of research studies aimed at identifying all factors that contribute to minimizing cost and maximizing postoperative care after total knee arthroplasty (TKA). Length of stay (LOS) has been defined as a significant factor that contributes to increased burden. We aimed at looking whether day of surgery has any significant effect on the LOS and postoperative complications following total knee arthroplasty (TKA). Materials and methods: Retrospective cohort study done at the Aga Khan University Hospital, Pakistan, from January 2007 to December 2015...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29371785/a-preliminary-evaluation-of-the-ability-of-keratotic-tissue-to-act-as-a-prognostic-indicator-of-hip-fracture-risk
#11
J Renwick Beattie, Diane Feskanich, M Clare Caraher, Mark R Towler
Studies have shown that Raman spectroscopic analysis of fingernail clippings can help differentiate between post-menopausal women who have and who have not suffered a fracture. However, all studies to date have been retrospective in nature, comparing the proteins in nails sourced from women, post-fracture. The objective of this study was to investigate the potential of a prospective test for hip fracture based on spectroscopic analysis of nail tissue. Archived toenail samples from post-menopausal women aged 50 to 63 years in the Nurses' Health Study were obtained and analysed by Raman spectroscopy...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29348710/the-protein-tyrosine-phosphatase-nonreceptor-22-ptpn22-r620w-functional-polymorphism-in-psoriasis
#12
Ghaleb Bin Huraib, Fahad Al Harthi, Misbahul Arfin, Sadaf Rizvi, Abdulrahaman Al-Asmari
Background: Psoriasis is a complex autoimmune disease caused by the interaction of genetic and environmental factors. PTPN22 gene polymorphism has been reported to affect psoriasis susceptibility; however, no data are available for Middle Eastern populations. Objective: The aim of this study was to investigate the association of PTPN22 (1858C/T) R620W polymorphism with psoriasis in a Saudi cohort. Methods: Saudi subjects (n = 306) including patients with psoriasis (n = 106) and matched controls (n = 200) were studied for PTPN22 variants using tetra-primer amplification refractory mutation system-polymerase chain reaction method...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29343996/does-hla-b27-status-influence-ankylosing-spondylitis-phenotype
#13
REVIEW
Amal Akassou, Youssef Bakri
The association of HLA-B27 with ankylosing spondylitis (AS) remains as one of the intriguing models that could exist between a molecule and human disease in medicine. Although it was reported in 1973, its contribution to AS and related spondyloarthritis continues to be a major challenge for scientific community. It is important to understand its etiopathogenic mechanism and its functions in these diseases. Although the diagnostic and prognostic roles of HLA-B27 in AS are still debated, there is an increasing interest for HLA-B27-based effects especially in HLA-B27(+) patients with AS...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29326532/rheological-properties-of-commercially-available-hyaluronic-acid-products-in-the-united-states-for-the-treatment-of-osteoarthritis-knee-pain
#14
Mathew Nicholls, Ajay Manjoo, Peter Shaw, Faizan Niazi, Jeffrey Rosen
Objective: The inconsistent results within the current literature regarding the efficacy of intra-articular-hyaluronic acid (IA-HA) for the treatment of knee osteoarthritis (OA) have been suggested to be due to intrinsic differences between individual HA products. The purpose of this investigation is to define the rheological differences between currently available HA products in the United States at the time of this study for the treatment of knee OA, which will help elaborate on the appropriateness of classifying HA products as a class opposed to as individual agents...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29326531/medial-pivot-in-total-knee-arthroplasty-literature-review-and-our-first-experience
#15
REVIEW
Luigi Sabatini, Salvatore Risitano, Gennaro Parisi, Ferdinando Tosto, Pier Francesco Indelli, Francesco Atzori, Alessandro Massè
Background: Traditional total knee implants designs, usually, are not able to reproduce the physiological kinematics of the knee, leaving almost 20% of the patients, those who underwent a total knee arthroplasty (TKA), not fully satisfied. Modern inserts are nowadays designed with a fully congruent medial compartment to reproduce the normal medial pivoting biomechanics of the knee. The aim of this article was to evaluate preliminary clinical improvement using the Medial Congruent (MC) insert as specific level of constraint...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29242702/proliferative-synovitis-of-the-shoulder-bursae-is-a-key-feature-for-discriminating-elderly-onset-rheumatoid-arthritis-mimicking-polymyalgia-rheumatica-from-polymyalgia-rheumatica
#16
Takeshi Suzuki, Ryochi Yoshida, Yuka Hidaka, Yu Seri
Semiquantitative scoring for subacromial bursa (SAB), subdeltoid bursa (SDB), and subcoracoid bursa by both gray-scale (GS) and power Doppler (PD) ultrasonography was performed in 15 patients with polymyalgia rheumatica (PMR) (72.6 ± 7.7 years old) and 15 patients with elderly onset rheumatoid arthritis with PMR-like onset (pm-EORA) (70.7 ± 7.0 years old) before starting treatment. The GS grades of SAB were significantly higher in the shoulders with pm-EORA than in the shoulders with PMR. The GS and PD scores of SAB and the PD scores of SDB were significantly higher in pm-EORA than in PMR cases...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29051707/efficacy-of-intra-articular-injection-of-a-newly-developed-plasma-rich-in-growth-factor-prgf-versus-hyaluronic-acid-on-pain-and-function-of-patients-with-knee-osteoarthritis-a-single-blinded-randomized-clinical-trial
#17
Seyed Ahmad Raeissadat, Seyed Mansoor Rayegani, Azadeh Gharooee Ahangar, Porya Hassan Abadi, Parviz Mojgani, Omid Gharooi Ahangar
BACKGROUND AND OBJECTIVES: Knee osteoarthritis is the most common joint disease. We aimed to compare the efficacy and safety of intra-articular injection of a newly developed plasma rich in growth factor (PRGF) versus hyaluronic acid (HA) on pain and function of patients with knee osteoarthritis. METHODS: In this single-blinded randomized clinical trial, patients with symptomatic osteoarthritis of knee were assigned to receive 2 intra-articular injections of our newly developed PRGF in 3 weeks or 3 weekly injections of HA...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28989290/feasibility-of-the-atlas-unicompartmental-knee-system-load-absorber-in-improving-pain-relief-and-function-in-patients-needing-unloading-of-the-medial-compartment-of-the-knee-1-year-follow-up-of-a-prospective-multicenter-single-arm-pilot-study-phantom-high-flex
#18
Konrad Slynarski, Jacek Walawski, Robert Smigielski, Willem van der Merwe
In young patients with medial knee osteoarthritis (OA), surgical intervention may not be desirable due to preferences to avoid bone cutting procedures, return to high activity levels, and prolong implant survival. The Atlas Knee System was designed to fill the gap between ineffective conservative treatments and invasive surgery. This single-arm study included 26 patients, aged 25 to 65 years, who completed 12 months of follow-up. All dimensions of the Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Knee Society Score significantly improved from baseline to 12 months...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28974919/patient-preferences-regarding-surgical-interventions-for-knee-osteoarthritis
#19
Claude T Moorman, Tom Kirwan, Jennifer Share, Christopher Vannabouathong
Surgical interventions for knee osteoarthritis (OA) have markedly different procedure attributes and may have dramatic differences in patient desirability. A total of 323 patients with knee OA were included in a dual response, choice-based conjoint analysis to identify the relative preference of 9 different procedure attributes. A model was also developed to simulate how patients might respond if presented with the real-world knee OA procedures, based on conservative assumptions regarding their attributes. The "amount of cutting and removal of the existing bone" required for a procedure had the highest preference score, indicating that these patients considered it the most important attribute...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28890658/magnetic-resonance-imaging-of-the-axial-skeleton-in-patients-with-spondyloarthritis-distribution-pattern-of-inflammatory-and-structural-lesions
#20
Patrick Hoffstetter, Mohammed H Al Suwaidi, Alexander Joist, Achim Benditz, Martin Fleck, Christian Stroszczynski, Christian Dornia
PURPOSE: Spondyloarthritis is a chronic inflammatory disorder of the musculoskeletal system driven by systemic enthesitis and typically involving the axial skeleton, ie, the spine and the sacroiliac joints. The purpose of this study was to assess the distribution pattern of inflammatory and structural magnetic resonance imaging (MRI) findings in spondyloarthritis. METHODS: Retrospective study of 193 patients with axial spondyloarthritis who received MRI of the spine and the sacroiliac joints...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
journal
journal
43285
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"