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International Journal of Vascular Medicine

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https://www.readbyqxmd.com/read/27885342/venous-adventitial-cystic-disease-a-review-of-45-cases-treated-since-1963
#1
REVIEW
Corey Bascone, Mazen Iqbal, Patrick Narh-Martey, Mauricio Szuchmacher, Michael Cicchillo, Kambhampaty V Krishnasastry
Purpose. To review and identify the most accurate ways of diagnosing and treating adventitial cystic disease (ACD) of the venous system. Methods. Cases of ACD were collected through three popular medical databases, including PubMed, Cochrane, OVID, and MEDLINE. After reviewing the literature, the sites of occurrence of 323 cases of adventitial cystic disease were documented, and all cases of arterial ACD were excluded. The clinical features, treatment, and subsequent course of 45 cases of venous ACD are included in this paper...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27853624/endothelial-dysfunction-of-patients-with-peripheral-arterial-disease-measured-by-peripheral-arterial-tonometry
#2
Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku, Yoshinori Inoue
Objective. Endothelial dysfunction plays a key role in atherosclerotic disease. Several methods have been reported to be useful for evaluating the endothelial dysfunction, and we investigated the endothelial dysfunction in patients with peripheral arterial disease (PAD) using peripheral arterial tonometry (PAT) test in this study. Furthermore, we examined the factors significantly correlated with PAT test. Methods. We performed PAT tests in 67 patients with PAD. In addition, we recorded the patients' demographics, including comorbidities, and hemodynamical status, such as ankle brachial pressure index (ABI)...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27830091/new-indices-of-endothelial-function-measured-by-digital-thermal-monitoring-of-vascular-reactivity-data-from-6084-patients-registry
#3
Morteza Naghavi, Albert A Yen, Alex W H Lin, Hirofumi Tanaka, Stanley Kleis
Background. Endothelial function is viewed as a barometer of cardiovascular health and plays a central role in vascular reactivity. Several studies showed digital thermal monitoring (DTM) as a simple noninvasive method to measure vascular reactivity that is correlated with atherosclerosis risk factors and coronary artery disease. Objectives. To further evaluate the relations between patient characteristics and DTM indices in a large patient registry. Methods. DTM measures were correlated with age, sex, heart rate, and systolic and diastolic blood pressure in 6084 patients from 18 clinics...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27559483/relationship-of-inflammatory-biomarkers-with-severity-of-peripheral-arterial-disease
#4
Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku, Yoshinori Inoue
Objective. The pentraxin family, including high-sensitivity C-reactive protein (hs-CRP), serum amyloid P (SAP), and pentraxin 3 (PTX3), has been identified as playing a key role in inflammatory reactions such as in atherosclerosis and cardiovascular disease. In this study, we examined the relationship between peripheral arterial disease (PAD) and serum levels of pentraxins. Methods. This study was undertaken via a retrospective review of PAD patients with surgical intervention for lesions of the common femoral artery...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27478641/simple-in-hospital-interventions-to-reduce-door-to-ct-time-in-acute-stroke
#5
Elyar Sadeghi-Hokmabadi, Aliakbar Taheraghdam, Mazyar Hashemilar, Reza Rikhtegar, Kaveh Mehrvar, Mehrdad Mehrara, Reshad Mirnour, Rogayyeh Hassasi, Hannane Aliyar, Mohammadamin Farzi, Somayyeh Hasaneh Tamar
Background. Intravenous tissue plasminogen activator, a time dependent therapy, can reduce the morbidity and mortality of acute ischemic stroke. This study was designed to assess the effect of simple in-hospital interventions on reducing door-to-CT (DTC) time and reaching door-to-needle (DTN) time of less than 60 minutes. Methods. Before any intervention, DTC time was recorded for 213 patients over a one-year period at our center. Five simple quality-improvement interventions were implemented, namely, call notification, prioritizing patients for CT scan, prioritizing patients for lab analysis, specifying a bed for acute stroke patients, and staff education...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27213056/paraoxonase-1-and-simvastatin-treatment-in-patients-with-stable-coronary-artery-disease
#6
Rafał Januszek
Background. Paraoxonase-1 (PON1) is the crucial antioxidant marker of high-density lipoproteins. The present study is aimed at assessing the effect of simvastatin treatment on PON1 activity and its relationship to Q192R and M55L polymorphisms in subjects with stable coronary artery disease (CAD). Methods. The patient group was composed of 53 individuals with stable CAD, and the control group included 53 sex-matched police officers without CAD. CAD patients were treated with simvastatin 40mg/day for 12 months...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27144026/investigation-of-tgf%C3%AE-1-induced-long-noncoding-rnas-in-endothelial-cells
#7
Krishna K Singh, Pratiek N Matkar, Adrian Quan, Laura-Eve Mantella, Hwee Teoh, Mohammed Al-Omran, Subodh Verma
Objective. To evaluate the relationship between TGFβ signaling and endothelial lncRNA expression. Methods. Human umbilical vein endothelial cell (HUVECs) lncRNAs and mRNAs were profiled with the Arraystar Human lncRNA Expression Microarray V3.0 after 24 hours of exposure to TGFβ1 (10 ng/mL). Results. Of the 30,584 lncRNAs screened, 2,051 were significantly upregulated and 2,393 were appreciably downregulated (P < 0.05) in response to TGFβ. In the same HUVEC samples, 2,148 of the 26,106 mRNAs screened were upregulated and 1,290 were downregulated...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27144025/carotid-intima-media-thickness-in-nondiabetic-hypertensive-nigerians-role-of-fasting-and-postprandial-blood-glucose
#8
B N Okeahialam, S A Muoneme, H O Kolade-Yunusa
Background/Aims. Carotid intima media thickness (CIMT) tracks atherosclerotic vascular disease. Hypertension and diabetes chiefly contribute to atherosclerosis with 75% of symptomatic cardiovascular disease cases having dysglycaemia even in normal cases. Hypothesising that postprandial hyperglycaemia contributes to cardiovascular morbidity, we sought to determine if any relationship existed between glycaemic profile in nondiabetic hypertensives and atherosclerosis. Methods. In a study of CIMT in nondiabetic, statin-naïve hypertensives, we evaluated fasting blood glucose (FBG) and 2-hour postprandial sugar (2hPPBG) in the patients and compared them with the CIMT...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27110403/ct-angiography-analysis-of-axillary-artery-diameter-versus-common-femoral-artery-diameter-implications-for-axillary-approach-for-transcatheter-aortic-valve-replacement-in-patients-with-hostile-aortoiliac-segment-and-advanced-lung-disease
#9
Rajiv Tayal, Humayun Iftikhar, Benjamin LeSar, Rahul Patel, Naveen Tyagi, Marc Cohen, Najam Wasty
Objective. The use of the axillary artery as an access site has lost favor in percutaneous intervention due to the success of these procedures from a radial or brachial alternative. However, these distal access points are unable to safely accommodate anything larger than a 7-French sheath. To date no studies exist describing the size of the axillary artery in relation to the common femoral artery in a patient population. We hypothesized that the axillary artery is of comparable size to the CFA in most patients and less frequently diseased...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27073699/renal-blood-flow-response-to-angiotensin-1-7-versus-hypertonic-sodium-chloride-7-5-administration-after-acute-hemorrhagic-shock-in-rats
#10
Maryam Maleki, Mehdi Nematbakhsh
Background. Angiotensin 1-7 (Ang1-7) plays an important role in renal circulation. Hemorrhagic shock (HS) may cause kidney circulation disturbance, and this study was designed to investigate the renal blood flow (RBF) response to Ang1-7 after HS. Methods. 27 male Wistar rats were subjected to blood withdrawal to reduce mean arterial pressure (MAP) to 45 mmHg for 45 min. The animals were treated with saline (group 1), Ang1-7 (300 ng·kg(-1) min(-1)), Ang1-7 in hypertonic sodium chloride 7.5% (group 3), and hypertonic solution alone (group 4)...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27066273/children-and-adolescent-obesity-associates-with-pressure-dependent-and-age-related-increase-in-carotid-and-femoral-arteries-stiffness-and-not-in-brachial-artery-indicative-of-nonintrinsic-arterial-wall-alteration
#11
Victoria García-Espinosa, Santiago Curcio, Juan Manuel Castro, Maite Arana, Gustavo Giachetto, Pedro Chiesa, Yanina Zócalo, Daniel Bia
Aim. To analyze if childhood obesity associates with changes in elastic, transitional, and/or muscular arteries' stiffness. Methods. 221 subjects (4-15 years, 92 females) were assigned to normal weight (NW, n = 137) or obesity (OB, n = 84) groups, considering their body mass index z-score. Age groups were defined: 4-8; 8-12; 12-15 years old. Carotid, femoral, and brachial artery local stiffness was determined through systodiastolic pressure-diameter and stress-strain relationships. To this end, arterial diameter and peripheral and aortic blood pressure (BP) levels and waveforms were recorded...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27034837/abpi-against-colour-duplex-scan-a-screening-tool-for-detection-of-peripheral-arterial-disease-in-low-resource-setting-approach-to-validation
#12
Janaka Weragoda, Rohini Seneviratne, Manuj C Weerasinghe, S M Wijeyaratne
Background. In Sri Lanka the ABPI has not been used as a screening tool to detect peripheral arterial disease (PAD) in epidemiological studies. This study was conducted to determine the best cutoff value of ABPI to detect PAD in Sri Lankan population. Methods. The ABPI measured by arterial Doppler to detect PAD was validated against colour duplex scan as the criterion using 165 individuals referred to vascular laboratory, National Hospital Sri Lanka. In all selected individuals ABPI was measured and lower limb colour duplex scan was performed...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26998360/single-low-density-lipoprotein-apheresis-does-not-improve-vascular-endothelial-function-in-chronically-treated-hypercholesterolemic-patients
#13
Kevin D Ballard, Eunice Mah, Yi Guo, Richard S Bruno, Beth A Taylor, Jo Ellen Beam, Donna M Polk, Paul D Thompson
Objective. To investigate vascular endothelial function (VEF) responses to a single low-density lipoprotein (LDL) apheresis session in hypercholesterolemic patients undergoing chronic treatment. Methods. We measured brachial artery flow-mediated dilation (FMD), plasma lipids, vitamin E (α- and γ-tocopherol), markers of oxidative/nitrative stress (malondialdehyde (MDA) and nitro-γ-tocopherol (NGT)), and regulators of NO metabolism (arginine (ARG) and asymmetric dimethylarginine (ADMA)) prior to (Pre) and immediately following (Post) LDL apheresis and at 1, 3, 7, and 14 d Post in 5 hypercholesterolemic patients (52 ± 11 y)...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26966581/dependence-of-proximal-gc-boxes-and-binding-transcription-factors-in-the-regulation-of-basal-and-valproic-acid-induced-expression-of-t-pa
#14
Erik Ulfhammer, Pia Larsson, Mia Magnusson, Lena Karlsson, Niklas Bergh, Sverker Jern
Objective. Endothelial tissue-type plasminogen activator (t-PA) release is a pivotal response to protect the circulation from occluding thrombosis. We have shown that the t-PA gene is epigenetically regulated and greatly induced by the histone deacetylase (HDAC) inhibitor valproic acid (VPA). We now investigated involvement of known t-PA promoter regulatory elements and evaluated dependence of potential interacting transcription factors/cofactors. Methods. A reporter vector with an insert, separately mutated at either the t-PA promoter CRE or GC box II or GC box III elements, was transfected into HT-1080 and HUVECs and challenged with VPA...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26966580/imaging-techniques-for-diagnosis-of-thoracic-aortic-atherosclerosis
#15
REVIEW
Wouter W Jansen Klomp, George J Brandon Bravo Bruinsma, Arnoud W van 't Hof, Jan G Grandjean, Arno P Nierich
The most severe complications after cardiac surgery are neurological complications including stroke which is often caused by emboli merging from atherosclerosis in the ascending aorta to the brain. Information about the thoracic aorta is crucial in reducing the embolization risk for both surgical open and closed chest procedures such as transaortic heart valve implantation. Several techniques are available to screen the ascending aorta, for example, transesophageal echocardiography (TEE), epiaortic ultrasound, TEE A-view method, manual palpation, computed tomography, and magnetic resonance imaging...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26942010/a-comparison-of-measures-of-endothelial-function-in-patients-with-peripheral-arterial-disease-and-age-and-gender-matched-controls
#16
Richard B Allan, Simon V Vun, J Ian Spark
This study compared flow-mediated dilatation (FMD), peripheral artery tonometry (PAT), and serum nitric oxide (NO) measures of endothelial function in patients with peripheral artery disease (PAD) against age/gender matched controls. 25 patients (mean age: 72.4 years, M : F 18 : 7) with established PAD and an age/gender matched group of 25 healthy controls (mean age: 72.4 years, M : F 18 : 7) were studied. Endothelial function was measured using the % FMD, reactive hyperemia index (RHI) using PAT and serum NO (μmol)...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26904291/vascular-health-in-american-football-players-cardiovascular-risk-increased-in-division-iii-players
#17
Deborah L Feairheller, Kristin R Aichele, Joyann E Oakman, Michael P Neal, Christina M Cromwell, Jessica M Lenzo, Avery N Perez, Naomi L Bye, Erica L Santaniello, Jessica A Hill, Rachel C Evans, Karla A Thiele, Lauren N Chavis, Allyson K Getty, Tia R Wisdo, JoAnna M McClelland, Kathleen Sturgeon, Pam Chlad
Studies report that football players have high blood pressure (BP) and increased cardiovascular risk. There are over 70,000 NCAA football players and 450 Division III schools sponsor football programs, yet limited research exists on vascular health of athletes. This study aimed to compare vascular and cardiovascular health measures between football players and nonathlete controls. Twenty-three athletes and 19 nonathletes participated. Vascular health measures included flow-mediated dilation (FMD) and carotid artery intima-media thickness (IMT)...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26904290/retrievable-inferior-vena-cava-filters-in-patients-with-cancer-complications-and-retrieval-success-rate
#18
Ana I Casanegra, Lisa M Landrum, Alfonso J Tafur
Active cancer (ACa) is strongly associated with venous thromboembolism and bleeding. Retrievable inferior vena cava filters (RIVCF) are frequently placed in these patients when anticoagulation cannot be continued. Objectives. To describe the complications and retrieval rate of inferior vena cava filters in patients with ACa. Methods. Retrospective review of 251 consecutive patients with RIVCF in a single institution. Results. We included 251 patients with RIVCF with a mean age of 58.1 years and a median follow-up of 5...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26904289/phenotypic-and-functional-changes-of-endothelial-and-smooth-muscle-cells-in-thoracic-aortic-aneurysms
#19
Anna Malashicheva, Daria Kostina, Aleksandra Kostina, Olga Irtyuga, Irina Voronkina, Larisa Smagina, Elena Ignatieva, Natalia Gavriliuk, Vladimir Uspensky, Olga Moiseeva, Jarle Vaage, Anna Kostareva
Thoracic aortic aneurysm develops as a result of complex series of events that alter the cellular structure and the composition of the extracellular matrix of the aortic wall. The purpose of the present work was to study the cellular functions of endothelial and smooth muscle cells from the patients with aneurysms of the thoracic aorta. We studied endothelial and smooth muscle cells from aneurysms in patients with bicuspid aortic valve and with tricuspid aortic valve. The expression of key markers of endothelial (CD31, vWF, and VE-cadherin) and smooth muscle (SMA, SM22α, calponin, and vimentin) cells as well extracellular matrix and MMP activity was studied as well as and apoptosis and cell proliferation...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/26881081/childhood-obesity-associates-haemodynamic-and-vascular-changes-that-result-in-increased-central-aortic-pressure-with-augmented-incident-and-reflected-wave-components-without-changes-in-peripheral-amplification
#20
Juan M Castro, Victoria García-Espinosa, Santiago Curcio, Maite Arana, Pedro Chiesa, Gustavo Giachetto, Yanina Zócalo, Daniel Bia
The aims were to determine if childhood obesity is associated with increased central aortic blood pressure (BP) and to characterize haemodynamic and vascular changes associated with BP changes in obese children and adolescents by means of analyzing changes in cardiac output (stroke volume, SV), arterial stiffness (aortic pulse wave velocity, PWV), peripheral vascular resistances (PVR), and net and relative contributions of reflected waves to the aortic pulse wave amplitude. We included 117 subjects (mean/range age: 10 (5-15) years, 49 females), who were obese (OB) or had normal weight (NW)...
2016: International Journal of Vascular Medicine
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