journal
MENU ▼
Read by QxMD icon Read
search

Journal of Pain Research

journal
https://www.readbyqxmd.com/read/29670397/effectiveness-of-fixed-site-high-frequency-transcutaneous-electrical-nerve-stimulation-in-chronic-pain-a-large-scale-observational-study
#1
Xuan Kong, Shai N Gozani
Objective: The objective of this study was to assess the effectiveness of fixed-site high-frequency transcutaneous electrical nerve stimulation (FS-TENS) in a real-world chronic pain sample. Background: There is a need for nonpharmacological treatment options for chronic pain. FS-TENS improved multisite chronic pain in a previous interventional study. Large observational studies are needed to further characterize its effectiveness. Methods: This retrospective observational cohort study examined changes in chronic pain measures following 60 days of FS-TENS use...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29670396/sustained-analgesic-effect-of-clonidine-co-polymer-depot-in-a-porcine-incisional-pain-model
#2
Jared T Wilsey, Julie H Block
Background: Previous research suggests that the α2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous injections are limited by rapid systemic absorption leading to off target effects and a brief analgesic duration of action. Purpose: The aim of this study was to examine the efficacy of a sustained-release clonidine depot, placed in the wound bed, in a pig incisional pain model...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29670395/bupivacaine-in-alginate-and-chitosan-nanoparticles-an-in-vivo-evaluation-of-efficacy-pharmacokinetics-and-local-toxicity
#3
Cíntia Maria Saia Cereda, Daniel Sebbe Mecatti, Juliana Zampoli Boava Papini, Diego Valério Bueno, Michelle Franz-Montan, Thalita Rocha, José Pedrazzoli Júnior, Eneida de Paula, Daniele Ribeiro de Araújo, Renato Grillo, Leonardo Fernandes Fraceto, Silvana Aparecida Calafatti, Giovana Radomille Tofoli
Objective: This study reports a preclinical evaluation of an alginate/chitosan nanoparticle formulation containing NovaBupi®, a racemic bupivacaine (BVC) containing 25% dextrobupivacaine and 75% levobupivacaine. Methods: New Zealand White rabbits (n=6) received intraoral or intrathecal injections of BVC 0.5% or BVC 0.5%-loaded alginate-chitosan nanoparticles (BVCALG ). BVC plasma levels and pharmacokinetic parameters were determined in blood samples of these rabbits...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29670394/management-of-chronic-pain-after-hernia-repair
#4
REVIEW
Kristoffer Andresen, Jacob Rosenberg
Chronic pain following inguinal hernia repair is a common problem and feared complication. Up to 16% of people experience chronic pain following the repair of a groin hernia. The aim of this review was to provide an overview of treatment strategies for patients with chronic pain following inguinal hernia repair based on best practice guidelines and current clinical routines. The optimal management of chronic pain following inguinal hernia surgery should begin with a thorough clinical examination to rule out other causes of chronic pain and to rule out a recurrence...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29670393/relationship-between-pain-outcomes-and-smoking-history-following-video-assisted-thoracic-surgery-for-lobectomy-a-retrospective-study
#5
Tak Kyu Oh, Kwhanmien Kim, Sanghoon Jheon, Sang-Hwan Do, Jung-Won Hwang, Jin Hee Kim, Young-Tae Jeon, In-Ae Song
Purpose: The relationship between chronic smoking history and postoperative pain remains controversial. This study aimed to elucidate this relationship in non-small cell lung cancer (NSCLC) patients who underwent video-assisted thoracic surgery (VATS) lobectomy. Patients and methods: This retrospective observational study included NSCLC patients treated with VATS lobectomy between January 2011 and July 2017. Demographic and clinical information, including preoperative smoking history, was collected...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29670392/cerebral-blood-flow-velocity-in-migraine-and-chronic-tension-type-headache-patients
#6
S Karacay Ozkalayci, B Nazliel, H Z Batur Caglayan, C Irkec
Introduction: The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication. Methods: A total of 50 patients (35 female, 15 male) were evaluated during a headache-free episode: 30 migraine patients without aura (mean age: 32±8 years), 10 migraine patients with aura (mean age: 34±4 years), and 10 patients with chronic tension-type headache (mean age: 34±5 years)...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29662325/sonic-hedgehog-signaling-in-spinal-cord-contributes-to-morphine-induced-hyperalgesia-and-tolerance-through-upregulating-brain-derived-neurotrophic-factor-expression
#7
Su Liu, Jun-Li Yao, Xin-Xin Wan, Zhi-Jing Song, Shuai Miao, Ye Zhao, Xiu-Li Wang, Yue-Peng Liu
Purpose: Preventing opioid-induced hyperalgesia and tolerance continues to be a major clinical challenge, and the underlying mechanisms of hyperalgesia and tolerance remain elusive. Here, we investigated the role of sonic hedgehog (Shh) signaling in opioid-induced hyperalgesia and tolerance. Methods: Shh signaling expression, behavioral changes, and neurochemical alterations induced by morphine were analyzed in male adult CD-1 mice with repeated administration of morphine...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29636630/the-impact-of-anxiety-and-catastrophizing-on-interleukin-6-responses-to-acute-painful-stress
#8
Asimina Lazaridou, Marc O Martel, Christine M Cahalan, Marise C Cornelius, Olivia Franceschelli, Claudia M Campbell, Jennifer A Haythornthwaite, Michael Smith, Joseph Riley, Robert R Edwards
Objective: To examine the influence of anxiety and pain-related catastrophizing on the time course of acute interleukin-6 (IL-6) responses to standardized noxious stimulation among patients with chronic pain. Methods: Data were collected from 48 participants in the following demographically matched groups: patients with chronic pain (n=36) and healthy controls (n=12). Participants underwent a series of Quantitative Sensory Testing (QST) procedures assessing responses to mechanical and thermal stimuli during two separate visits, in a randomized order...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29628772/incidence-and-association-factors-for-the-development-of-chronic-post-hysterectomy-pain-at-4-and-6-month-follow-up-a-prospective-cohort-study
#9
Ban Leong Sng, Yin Ying Ching, Nian-Lin R Han, Farida Binte Ithnin, Rehena Sultana, Pryseley Nkouibert Assam, Alex Tiong Heng Sia
Chronic pain has major adverse effects on health-related quality of life and contributes to significant socioeconomic burden. Hysterectomy is a very common gynecological surgery, resulting in chronic post-hysterectomy pain (CPHP), an important pain syndrome. We conducted a prospective cohort study in 216 Asian women who underwent abdominal or laparoscopic hysterectomy for benign conditions. Demographic, psychological, and perioperative data were recorded. Postoperative 4- and 6-month phone surveys were conducted to assess the presence of CPHP and functional impairment...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29628771/activation-of-spinal-dorsal-horn-p2y-13-receptors-can-promote-the-expression-of-il-1%C3%AE-and-il-6-in-rats-with-diabetic-neuropathic-pain
#10
Rui Zhou, Tao Xu, XiaoHong Liu, YuanShou Chen, DeYing Kong, Hong Tian, Mingxia Yue, Dujuan Huang, Junwei Zeng
Objective: The dorsal horn P2Y13 receptor is involved in the development of pain behavior induced by peripheral nerve injury. It is unclear whether the expression of proinflammatory cytokines interleukin (IL)-1β and IL-6 at the spinal dorsal horn are influenced after the activation of P2Y13 receptor in rats with diabetic neuropathic pain (DNP). Methods: A rat model of type 1 DNP was induced by intraperitoneal injection of streptozotocin (STZ). We examined the expression of P2Y13 receptor, Iba-1, IL-1β, IL-6, JAK2, STAT3, pTyr1336 , and pTyr1472 NR2B in rat spinal dorsal horn...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29615846/eotaxin-levels-in-patients-with-primary-dysmenorrhea
#11
Evrim Gul, Ebru Celik Kavak
Purpose: Primary dysmenorrhea (PD) is a common cause of pelvic pain that can cause limitations in daily activities. Treatment options sometimes result in failure, suggesting that different mechanisms may be effective in etiopathogenesis. Eosinophils are cells that are present in endometrium only in the perimenstrual period. The aim of this study was to evaluate the levels of eotaxin, a potent eosinophilic chemoattractant, in patients with PD. Patients and methods: Thirty patients with PD and thirty healthy women were included in the study...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29606887/electrical-peripheral-nerve-stimulation-relieves-bone-cancer-pain-by-inducing-arc-protein-expression-in-the-spinal-cord-dorsal-horn
#12
Ke-Fu Sun, Wan-Wen Feng, Yue-Peng Liu, Yan-Bin Dong, Li Gao, Hui-Lin Yang
Objective: The analgesic effect on chronic pain of peripheral nerve stimulation (PNS) has been proven, but its underlying mechanism remains unknown. Therefore, this study aimed to assess the analgesic effect of PNS on bone cancer pain in a rat model and to explore the underlying mechanism. Materials and methods: PNS on sciatic nerves with bipolar electrode was performed in both naïve and bone cancer pain model rats. Then, the protein levels of activity-regulated cytoskeleton-associated protein (Arc), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor 1 (GluA1), and phosphate N -methyl-d-aspartic acid-type glutamate receptor subunit 2B (pGluNR2B) in spinal cord were evaluated by immunohistochemistry and Western blotting...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29588616/optimal-management-of-orthodontic-pain
#13
REVIEW
Francielle Topolski, Alexandre Moro, Gisele Maria Correr, Sasha Cristina Schimim
Pain is an undesirable side effect of orthodontic tooth movement, which causes many patients to give up orthodontic treatment or avoid it altogether. The aim of this study was to investigate, through an analysis of the scientific literature, the best method for managing orthodontic pain. The methodological aspects involved careful definition of keywords and diligent search in databases of scientific articles published in the English language, without any restriction of publication date. We recovered 1281 articles...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29588615/management-of-pain-in-patients-with-temporomandibular-disorder-tmd-challenges-and-solutions
#14
REVIEW
Alfonso Gil-Martínez, Alba Paris-Alemany, Ibai López-de-Uralde-Villanueva, Roy La Touche
Thanks to advances in neuroscience, biopsychosocial models for diagnostics and treatment (including physical, psychological, and pharmacological therapies) currently have more clinical support and scientific growth. At present, a conservative treatment approach prevails over surgery, given it is less aggressive and usually results in satisfactory clinical outcomes in mild-moderate temporomandibular disorder (TMD). The aim of this review is to evaluate the recent evidence, identify challenges, and propose solutions from a clinical point of view for patients with craniofacial pain and TMD...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29588614/practice-and-bias-in-intraoperative-pain-management-results-of-a-cross-sectional-patient-study-and-a-survey-of-anesthesiologists
#15
Stephen Ward, Charlotte Guest, Ian Goodall, Carsten Bantel
Background: Perioperative pain carries a considerable risk of becoming persistent; hence aggressive preventive approaches are advocated. Persistently high prevalence of postoperative pain, however, suggests anesthesiologists underuse these strategies. A prospective cross-sectional study of patients in the postanesthetic care unit (PACU) and a survey of anesthesiologists were thus conducted to evaluate practice and uncover bias in intraoperative pain management. Methods: Notes of PACU patients were reviewed and information regarding surgical context, comorbidities, and analgesic administration was retrieved...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29588613/buprenorphine-and-pain-treatment-in-pediatric-patients-an-update
#16
Erendira Vicencio-Rosas, María Gabriela Pérez-Guillé, Carmen Flores-Pérez, Janett Flores-Pérez, Francisca Trujillo-Jiménez, Juan Luis Chávez-Pacheco
Introduction: The usual management of moderate to severe pain is based on the use of opioids. Buprenorphine (BPN) is an opioid with an analgesic potency 50 times greater than that of morphine. It is widely used in various pain models and has demonstrated efficacy and safety in adult patients; however, there are insufficient clinical trials in pediatric populations. Purpose: The aim of this study was to perform an updated meta-analysis on the implementation of BPN in the treatment of pain in the pediatric population...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29588612/radiation-induced-neuropathic-pain-successfully-treated-with-systemic-lidocaine-administration
#17
A Ram Doo, Yu Seob Shin, Seonwoo Yoo, Jong Kwan Park
Radiation-induced neuropathic pain is a rare but devastating complication following cancer treatment. It is often progressive, refractory to conservative treatment, and sometimes irreversible. The exact mechanism of radiation-induced neuropathic pain is unknown, but it is associated with perineural fibrosis, atrophy, and ischemia. Systemic administration of local anesthetics is known to be effective for various acute and chronic painful diseases, such as neuropathic pain, as well as inflammatory and nociceptive pains...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29563832/the-role-of-posttraumatic-stress-symptoms-on-chronic-pain-outcomes-in-chronic-pain-patients-referred-to-rehabilitation
#18
Sophie Lykkegaard Ravn, Henrik Bjarke Vaegter, Thomas Cardel, Tonny Elmose Andersen
Objectives: Posttraumatic stress symptoms (PTSS) are highly prevalent in chronic pain patients and may affect pain symptomatology negatively, but there is still a great need to explore exactly how this occurs. Therefore, this study investigated differences in pain intensity, pain-related disability, and psychological distress between chronic pain patients not exposed to a trauma, patients exposed to a trauma with no PTSS, and patients exposed to a trauma with PTSS. Moreover, the moderating effects of PTSS on the associations between pain intensity and pain-related disability and psychological distress were investigated...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29563831/serotonin-receptor-agonists-in-the-acute-treatment-of-migraine-a-review-on-their-therapeutic-potential
#19
REVIEW
Andrea Negro, Angela Koverech, Paolo Martelletti
Migraine is an important socioeconomic burden and is ranked the sixth cause of years of life lost because of disability in the general population and the third cause of years of life lost in people younger than 50 years. The cornerstone of pharmacological treatment is represented by the acute therapy. The serotonin (5-hydroxytryptamine [5-HT]) receptor subtype 1B /1D agonists, called triptans, are nowadays the first-line acute therapy for patients who experience moderate-to-severe migraine attacks. Unfortunately, a high percentage of patients are not satisfied with this acute treatment, either for lack of response or side effects...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29563830/different-mechanisms-of-contralateral-or-ipsilateral-acupuncture-to-modulate-the-brain-activity-in-patients-with-unilateral-chronic-shoulder-pain-a-pilot-fmri-study
#20
Shuai Zhang, Xu Wang, Chao-Qun Yan, Shang-Qing Hu, Jian-Wei Huo, Zhong-Yan Wang, Ping Zhou, Chun-Hong Liu, Cun-Zhi Liu
Background: Chronic shoulder pain (CSP) is a common disease causing pain and functional limitation, which is highly prevalent and has substantial negative effects on the quality of life. Acupuncture has gained popularity and has been accepted gradually by many countries because it can successfully treat patients with chronic pain, but the specific brain mechanisms under acupuncture treatment for CSP remain unclear. Therefore, in this study, we aimed to 1) compare the clinical effects between acupuncture at the contralateral and ipsilateral Tiaokou (ST 38) point in patients with unilateral shoulder pain and 2) explore how contralateral- and ipsilateral-acupuncture modulates the regional homogeneity (ReHo) of patients with CSP...
2018: Journal of Pain Research
journal
journal
43246
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"