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Journal of Pain Research

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https://www.readbyqxmd.com/read/28096691/pain-acceptance-potentially-mediates-the-relationship-between-pain-catastrophizing-and-post-surgery-outcomes-among-compensated-lumbar-fusion-patients
#1
Cassie Dance, M Scott DeBerard, Jessica Gundy Cuneo
PURPOSE: Chronic low back pain is highly prevalent and often treatment recalcitrant condition, particularly among workers' compensation patients. There is a need to identify psychological factors that may predispose such patients to pain chronicity. The primary aim of this study was to examine whether pain acceptance potentially mediated the relationship between pain catastrophizing and post-surgical outcomes in a sample of compensated lumbar fusion patients. PATIENTS AND METHODS: Patients insured with the Workers Compensation Fund of Utah and who were at least 2 years post-lumbar fusion surgery completed an outcome survey...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28096690/the-relationship-between-findings-on-magnetic-resonance-imaging-and-previous-history-of-low-back-pain
#2
Juichi Tonosu, Hiroyuki Oka, Ko Matsudaira, Akiro Higashikawa, Hiroshi Okazaki, Sakae Tanaka
The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one participants without current LBP were included. Sagittal T2-weighted MRI was used to assess the intervertebral space from T12/L1 to L5/S1. These images were classified into five grades based on the Pfirrmann grading system...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28096689/influence-of-exercise-on-visceral-pain-an-explorative-study-in-healthy-volunteers
#3
Laura Jgm van Weerdenburg, Christina Brock, Asbjørn Mohr Drewes, Harry van Goor, Marjan de Vries, Oliver Hg Wilder-Smith
BACKGROUND AND OBJECTIVES: Contradictory results have been found about the effect of different exercise modalities on pain. The aim of this study was to investigate the early effects of aerobic and isometric exercise on different types of experimental pain, including visceral pain, compared to an active control condition. METHODS: Fifteen healthy subjects (6 women, mean [standard deviation] age 25 [6.5] years) completed 3 interventions consisting of 20 minutes of aerobic cycling, 12 minutes of isometric knee extension and a deep breathing procedure as active control...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28058032/understanding-patient-perspectives-on-management-of-their-chronic-pain-online-survey-protocol
#4
Manasi Gaikwad, Simon Vanlint, G Lorimer Moseley, Murthy N Mittinty, Nigel Stocks
BACKGROUND: It is widely recognized that both doctors and patients report discontent regarding pain management provided and received. The impact of chronic pain on an individual's life resonates beyond physical and mental suffering; equal or at times even greater impact is observed on an individual's personal relationships, ability to work, and social interactions. The degree of these effects in each individual varies, mainly because of differences in biological factors, social environment, past experiences, support, and belief systems...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28053554/postoperative-opioid-sparing-with-injectable-hydroxypropyl-%C3%AE-cyclodextrin-diclofenac-pooled-analysis-of-data-from-two-phase-iii-clinical-trials
#5
Tong J Gan, Neil Singla, Stephen E Daniels, Douglas A Hamilton, Peter G Lacouture, Christian Rd Reyes, Daniel B Carr
PURPOSE: Use of nonopioid analgesics (including nonsteroidal anti-inflammatory drugs) for postoperative pain management can reduce opioid consumption and potentially prevent opioid-related adverse events. This study examined the postoperative opioid-sparing effect of repeated-dose injectable diclofenac formulated with hydroxypropyl-β-cyclodextrin (HPβCD)-diclofenac. PATIENTS AND METHODS: Pooled data from two double-blind, randomized, placebo- and active comparator-controlled Phase III trials were analyzed...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28031726/complex-regional-pain-syndrome-medical-and-legal-ramifications-of-clinical-variability-and-experience-and-perspective-of-a-practicing-clinician
#6
R P Lazaro
OBJECTIVE: The aim of this study was to demonstrate the ramifications of clinical variability of complex regional pain syndrome (CRPS) and how they can affect the various aspects of this condition, favorably or unfavorably, for both patients and participating medical and legal professionals. METHODS: Twelve patients diagnosed with CRPS at different times in the past 25 years were followed up, and their signs and symptoms were reviewed for variability. None had preexisting or ongoing medical disorders and prior injury to the peripheral nerves or musculoskeletal tissues...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28031725/skin-matters-the-role-of-keratinocytes-in-nociception-a-rational-argument-for-the-development-of-topical-analgesics
#7
REVIEW
Jan M Keppel Hesselink, David J Kopsky, Arun K Bhaskar
Treatment of neuropathic pain using topical formulations is still in its infancy. Only few topical analgesic formulations have become available for clinical use, and among these, analgesic creams are still rare. This is unfortunate because analgesic creams offer a number of advantages over patches, such as convenience, ease of adapting the frequency of application, and dose, and "rubbing cream where it hurts" involves the patient much more in the therapeutic process compared to patches and other localized treatment modalities...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28031727/can-consistent-benchmarking-within-a-standardized-pain-management-concept-decrease-postoperative-pain-after-total-hip-arthroplasty-a-prospective-cohort-study-including-367-patients
#8
Achim Benditz, Felix Greimel, Patrick Auer, Florian Zeman, Antje Göttermann, Joachim Grifka, Winfried Meissner, Frederik von Kunow
BACKGROUND: The number of total hip replacement surgeries has steadily increased over recent years. Reduction in postoperative pain increases patient satisfaction and enables better mobilization. Thus, pain management needs to be continuously improved. Problems are often caused not only by medical issues but also by organization and hospital structure. The present study shows how the quality of pain management can be increased by implementing a standardized pain concept and simple, consistent, benchmarking...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/28008281/nicoboxil-nonivamide-cream-effectively-and-safely-reduces-acute-nonspecific-low-back-pain-a-randomized-placebo-controlled-trial
#9
Zuzana Blahova, Janina Claudia Holm, Thomas Weiser, Erika Richter, Matthias Trampisch, Elena Akarachkova
BACKGROUND/OBJECTIVE: Low back pain affects many patients and has a high socioeconomic impact. Topical capsaicinoids have been used for decades to treat musculoskeletal pain. This study investigated the effects of the fixed dose combination (FDC) of nonivamide (a capsaicinoid) and nicoboxil (a nicotinic acid ester) cream in the treatment of acute nonspecific low back pain. MATERIALS AND METHODS: This phase III randomized, double-blind, placebo-controlled, multinational, multi-center trial investigated efficacy, safety, and tolerability of topical nicoboxil 1...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/28003771/heart-rate-variability-during-treatment-of-breakthrough-pain-in-patients-with-advanced-cancer-a-pilot-study
#10
Eva Katharina Masel, Patrick Huber, Tobias Engler, Herbert Hans Watzke
BACKGROUND: Decisions on the intensity of analgesic therapy and judgments regarding its efficacy are difficult at the end of life, when many patients are not fully conscious and pain is a very common symptom. In healthy individuals and in postoperative settings, nociception and subsequent pain relief have been shown to induce changes in the autonomic nervous system (ANS), which can be detected by measuring heart rate variability (HRV). OBJECTIVES: The changes in the ANS were studied by measuring HRV during opioid therapy for cancer breakthrough pain (CBTP) in palliative-care patients with cancer and compared these changes with patient-reported pain levels on a numeric rating scale (NRS)...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27994482/dysesthesia-symptoms-produced-by-sensorimotor-incongruence-in-healthy-volunteers-an-electroencephalogram-study
#11
Osamu Katayama, Michihiro Osumi, Takayuki Kodama, Shu Morioka
OBJECTIVES: Pathological pain such as phantom limb pain is caused by sensorimotor incongruence. Several studies with healthy participants have clearly indicated that dysesthesia, which is similar to pathological pain, is caused by incongruence between proprioception and/or motor intention and visual feedback. It is not clear to what extent dysesthesia may be caused by incongruence between motor intention and visual feedback or by incongruence between proprioception and visual feedback...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27994481/pharmacotherapeutic-considerations-for-chronic-pain-in-chronic-kidney-and-end-stage-renal-disease
#12
EDITORIAL
Roy O Mathew, Jeffrey J Bettinger, Erica L Wegrzyn, Jeffrey Fudin
No abstract text is available yet for this article.
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27994480/combining-pain-therapy-with-lifestyle-the-role-of-personalized-nutrition-and-nutritional-supplements-according-to-the-simpar-feed-your-destiny-approach
#13
REVIEW
Manuela De Gregori, Carolina Muscoli, Michael E Schatman, Tiziana Stallone, Fabio Intelligente, Mariangela Rondanelli, Francesco Franceschi, Laura Isabel Arranz, Silvia Lorente-Cebrián, Maurizio Salamone, Sara Ilari, Inna Belfer, Massimo Allegri
Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, omega-3 fatty acids, and curcumin supplementation as key elements in modulating the efficacy of analgesic treatments, including opioids. These main topics were addressed during the first edition of the Study In Multidisciplinary Pain Research workshop: "FYD (Feed Your Destiny): Fighting Pain", held on April 7, 2016, in Rome, Italy, which was sponsored by a grant from the Italian Ministry of Instruction on "Nutraceuticals and Innovative Pharmacology"...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27994479/transsacrococcygeal-approach-to-ganglion-impar-radiofrequency-application-for-the-treatment-of-chronic-intractable-coccydynia
#14
Cemil Adas, Ugur Ozdemir, Huseyin Toman, Nurettin Luleci, Emel Luleci, Hilal Adas
OBJECTIVE: Coccydynia is defined as pain in the coccygeal region. Among the many causes of coccydynia, the most common cause is trauma as a result of falling on the buttocks, repetitive microtrauma, or childbirth. Several methods are currently used for the treatment of coccydynia, including nonsteroidal anti-inflammatory drugs, intrarectal manipulation, epidural injections, ganglion impar blocks, and radiofrequency treatment (RFT). Wemm and Saberski used the transacrococcygeal methods to reduce tissue trauma...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27980436/an-investigation-of-completion-times-on-the-screener-and-opioid-assessment-for-patients-with-pain-revised-soapp-r
#15
Matthew D Finkelman, Ronald J Kulich, Stephen F Butler, William C Jackson, Franklin D Friedman, Niels Smits, Scott G Weiner
BACKGROUND: Respondents' scores to the Screener and Opioid Assessment for Patients with Pain - revised (SOAPP-R) have been shown to be predictive of aberrant drug-related behavior (ADB). However, research is lacking on whether an individual's completion time (the amount of time that he/she takes to finish the screener) has utility in predicting ADB, despite the fact that response speed has been useful in predicting behavior in other fields. The purpose of this study was to evaluate the degree to which SOAPP-R completion time is predictive of ADB...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27980435/erratum-humanistic-and-economic-burden-of-fibromyalgia-in-japan-corrigendum
#16
(no author information available yet)
[This corrects the article on p. 967 in vol. 9, PMID: 27853390.].
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27980434/trpa1-in-the-spinal-dorsal-horn-is-involved-in-post-inflammatory-visceral-hypersensitivity-in-vivo-study-using-tnbs-treated-rat-model
#17
Qian Li, Cheng-Hao Guo, Mohammed Ali Chowdhury, Tao-Li Dai, Wei Han
INTRODUCTION: The transient receptor potential ankyrin-1 (TRPA1) channel, a pain transducer and amplifier, is drawing increasing attention in the field of visceral hypersensitivity, commonly seen in irritable bowel syndrome and inflammatory bowel disease. However, the role of TRPA1 in visceral nociception during post-inflammatory states is not well defined. Here, we explore the correlation between TRPA1 expression in the spinal dorsal horn (SDH) and persistent post-inflammatory visceral hypersensitivity...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27942233/risks-associated-with-borrowing-and-sharing-of-prescription-analgesics-among-patients-observed-by-pain-management-physicians-in-croatia-a-qualitative-study
#18
Filipa Markotic, Livia Puljak
BACKGROUND: Understanding and improving patient safety is a key issue in medicine. One of the potential threats to patient safety is the sharing of medication among patients, which is a form of self-medication. This study analyzed experiences and attitudes of pain management physicians (PMPs) about sharing prescription analgesics among patients. METHODS: This qualitative study was conducted by semi-structured interviews among PMPs employed in Croatian pain clinics...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27942232/prevalence-of-different-pain-categories-based-on-pain-spreading-on-the-bodies-of-older-adults-in-sweden-a-descriptive-level-and-multilevel-association-with-demographics-comorbidities-medications-and-certain-lifestyle-factors-pains65
#19
E Dragioti, B Larsson, L Bernfort, L Å Levin, B Gerdle
BACKGROUND AND OBJECTIVE: There is limited knowledge about the prevalence of pain and its relation to comorbidities, medication, and certain lifestyle factors in older adults. To address this limitation, this cross-sectional study examined the spreading of pain on the body in a sample of 6611 subjects ≥65 years old (mean age = 75.0 years; standard deviation [SD] = 7.7) living in southeastern Sweden. METHODS: Sex, age, comorbidities, medication, nicotine, alcohol intake, and physical activity were analyzed in relation to the following pain categories: local pain (LP) (24...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27932896/involvement-of-spinal-glutamate-transporter-1-in-the-development-of-mechanical-allodynia-and-hyperalgesia-associated-with-type-2-diabetes
#20
Jinshan Shi, Ke Jiang, Zhaoduan Li
Little is known about the effects of the development of type 2 diabetes on glutamate homeostasis in the spinal cord. Therefore, we quantified the extracellular levels of glutamate in the spinal cord of Zucker diabetic fatty (ZDF) rats using in vivo microdialysis. In addition, protein levels of glutamate transporter-1 (GLT-1) in the spinal cord of ZDF rats were measured using Western blot. Finally, the effects of repeated intrathecal injections of ceftriaxone, which was previously shown to enhance GLT-1 expression, on the development of mechanical allodynia and hyperalgesia as well as on basal extracellular level of glutamate and the expression of GLT-1 in the spinal cord of ZDF rats were evaluated...
2016: Journal of Pain Research
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