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Journal of Pain Research

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https://www.readbyqxmd.com/read/28615968/effects-of-dezocine-on-prevention-of-propofol-injection-pain-a-meta-analysis
#1
REVIEW
Chengmao Zhou, Yuting Yang, Yu Zhu, Lin Ruan
OBJECTIVE: The objective of this study was to evaluate the effects of dezocine on the prevention of propofol injection pain. MATERIALS AND METHODS: We searched for randomized controlled trials (RCTs) of dezocine in preventing propofol injection pain, from inception to April 2016, in PubMed, Embase, Cochrane Library, and CNKI. Next, two reviewers independently screened literature, extracted data, and assessed quality in accordance with the inclusion and exclusion criteria...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615967/assessment-of-direct-analgesic-effect-of-duloxetine-for-chronic-low-back-pain-post-hoc-path-analysis-of-double-blind-placebo-controlled-studies
#2
Hiroyuki Enomoto, Shinji Fujikoshi, Jumpei Funai, Nao Sasaki, Michael H Ossipov, Toshinaga Tsuji, Levent Alev, Takahiro Ushida
BACKGROUND: Comorbid depression and depressive symptoms are common in patients with chronic low back pain (CLBP). Duloxetine is clinically effective in major depressive disorder and several chronic pain states, including CLBP. The objective of this post hoc meta-analysis was to assess direct and indirect analgesic efficacy of duloxetine for patients with CLBP in previous clinical trials. METHODS: Post hoc path analyses were conducted of 3 randomized, double-blind, clinical studies of patients receiving duloxetine or placebo for CLBP...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615966/acute-physiological-and-electrical-accentuation-of-vagal-tone-has-no-effect-on-pain-or-gastrointestinal-motility-in-chronic-pancreatitis
#3
Jacob Juel, Christina Brock, Søren S Olesen, Adnan Madzak, Adam D Farmer, Qasim Aziz, Jens B Frøkjær, Asbjørn Mohr Drewes
BACKGROUND: The effective management of pain in chronic pancreatitis (CP) remains a therapeutic challenge. Analgesic drugs, such as opioids, and the underlying pathology can impair gut function. The autonomic nervous system influences hormone secretion and gut motility. In healthy volunteers, electrical (using noninvasive transcutaneous vagal nerve stimulation [t-VNS]) and physiological (using deep slow breathing [DSB]) modulation of parasympathetic tone results in pain attenuation and enhanced gut motility...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615965/impact-of-a-value-based-insurance-design-for-physical-therapy-to-treat-back-pain-on-care-utilization-and-cost
#4
Daniel D Maeng, Anthony Graboski, Peiling L Allison, Dorothy Y Fisher, John B Bulger
OBJECTIVE: To assess the impact of a value-based insurance design providing enhanced access to physical therapy (PT) for treatment of back pain on treatment patterns and cost of care. STUDY DESIGN: A retrospective analysis of claims data obtained from Geisinger Health Plan (GHP). In April 2013, GHP began offering "PT bundle" - i.e., a bundle of up to five PT visits for a single one-time copay that can be renewed for another bundle of five PT visits - for its employer-based plan members with back pain...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615964/development-and-performance-of-a-diagnostic-prognostic-scoring-system-for-breakthrough-pain
#5
Boaz Gedaliahu Samolsky Dekel, Marco Palma, Maria Cristina Sorella, Alberto Gori, Alessio Vasarri, Rita Maria Melotti
OBJECTIVES: Variable prevalence and treatment of breakthrough pain (BTP) in different clinical contexts are partially due to the lack of reliable/validated diagnostic tools with prognostic capability. We report the statistical basis and performance analysis of a novel BTP scoring system based on the naïve Bayes classifier (NBC) approach and an 11-item IQ-BTP validated questionnaire. This system aims at classifying potential BTP presence in three likelihood classes: "High," "Intermediate," and "Low...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615963/frequency-dependent-changes-in-sensorimotor-and-pain-affective-systems-induced-by-empathy-for-pain
#6
Yoshimasa Motoyama, Katsuya Ogata, Sumio Hoka, Shozo Tobimatsu
BACKGROUND: Empathy for pain helps us to understand the pain of others indirectly. To better comprehend the processing of empathic pain, we report the frequency-dependent modulation of cortical oscillations induced by watching movies depicting pain using high-density electroencephalography (EEG), magnetoencephalography (MEG), and motor evoked potentials (MEP). METHODS: Event-related desynchronization of EEG and MEG was assessed while participants viewed videos of painful (needle) or neutral (cotton swab) situations...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28615962/sensitivity-to-pain-traumatization-scale-development-validation-and-preliminary-findings
#7
Joel Katz, Samantha R Fashler, Claire Wicks, M Gabrielle Pagé, Kaley M Roosen, Valery Kleiman, Hance Clarke
BACKGROUND: This article reports three studies describing the development and validation of the 12-item Sensitivity to Pain Traumatization Scale (SPTS-12). SPT refers to the anxiety-related cognitive, emotional, and behavioral reactions to pain that resemble the features of a traumatic stress reaction. METHODS: In Study 1, a preliminary set of 79 items was administered to 116 participants. The data were analyzed by using combined nonparametric and parametric item response theory resulting in a 12-item scale with a one-factor structure and good preliminary psychometric properties...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28603429/development-and-validation-of-an-arabic-language-headache-questionnaire-for-population-based-surveys
#8
Naglaa A El-Sherbiny, Hatem Samir Shehata, Hanan Amer, Alaa Elmazny, Mohamed Masoud, Hanan Helmy, Nevin M Shalaby
BACKGROUND: The reported prevalence of headache disorders in Arab regions varies considerably between countries. This may be due to a lack of standardized survey instruments that capture the prevalence. PURPOSE OF THE STUDY: Our goal was to construct and validate a structured headache questionnaire for Arabic-speaking headache patients to be used as an epidemiological survey instrument. METHODS: We developed a culturally adapted interviewer-administered questionnaire in Arabic language comprising two sets of questions...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28603428/upregulation-of-mir-375-level-ameliorates-morphine-analgesic-tolerance-in-mouse-dorsal-root-ganglia-by-inhibiting-the-jak2-stat3-pathway
#9
Haiqin Li, Rong Tao, Jing Wang, Lingjie Xia
Several lines of evidence indicate that microRNAs (miRNAs) modulate tolerance to the analgesic effects of morphine via regulation of pain-related genes, making dysregulation of miRNA levels a clinical target for controlling opioid tolerance. However, the precise mechanisms by which miRNAs regulate opioid tolerance are unclear. In the present study, we noted that the miR-375 level was downregulated but the expression of Janus kinase 2 (JAK2) was upregulated in mouse dorsal root ganglia (DRG) following chronic morphine treatment...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579825/durapain-in-symptomatic-treatment-of-severe-acute-pain-a-post-marketing-prospective-multicenter-observational-study-prime-study
#10
Kshitij Shah, Omvijay B Chaudhari, Palash Gupta, R Hom Chaudhuri, Ranjan Kamilya, Shreedhar S Kulkarni, S Subbaiah, Zubair H Sorathia, Gauri Billa
OBJECTIVE: To assess the effectiveness, overall tolerability, and gastrointestinal (GI) tolerability of Durapain (fixed dose combination of tramadol hydrochloride immediate release [50 mg] and diclofenac sodium sustained release [75 mg]) in symptomatic treatment of severe acute pain in physician's routine clinical practice. MATERIALS AND METHODS: In this prospective, multicenter, observational, post-marketing study, adult patients (aged 18-60 years) with severe acute pain were treated with tramadol hydrochloride/diclofenac sodium as per approved prescribing information...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579824/tumor-necrosis-factor-%C3%AE-modulates-sodium-activated-potassium-channel-slick-in-rat-dorsal-horn-neurons-via-p38-mapk-activation-pathway
#11
Kun Wang, Feng Wang, Jun-Ping Bao, Zhi-Yang Xie, Lu Chen, Bao-Yi Zhou, Xin-Hui Xie, Xiao-Tao Wu
The dorsal horn (DH) of the spinal cord is the integrative center that processes and transmits pain sensation. Abnormal changes in ion channel expression can enhance the excitability of pain-related DH neurons. Sodium-activated potassium (KNa) channels are highly expressed particularly in the central nervous system; however, information about whether rat DH neurons express the SLICK channel protein is lacking, and the direct effects on SLICK in response to inflammation and the potential signaling pathway mediating such effects are yet to be elucidated...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579823/use-of-immediate-release-opioids-as-supplemental-analgesia-during-management-of-moderate-to-severe-chronic-pain-with-buprenorphine-transdermal-system
#12
Sanford Silverman, Robert B Raffa, Marc J Cataldo, Monica Kwarcinski, Steven R Ripa
BACKGROUND: The buprenorphine transdermal system (BTDS) is approved in the US for the management of chronic pain. Due to its high affinity for μ-opioid receptors with a slow dissociation profile, buprenorphine may potentially displace or prevent the binding of competing μ-opioid-receptor agonists, including immediate-release (IR) opioids, in a dose-dependent manner. Health care professionals may assume that the use of IR opioids for supplemental analgesia during BTDS therapy is not acceptable...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579822/quantitative-sensory-testing-measures-individual-pain-responses-in-emergency-department-patients
#13
Kevin J Duffy, Katharyn L Flickinger, Jeffrey T Kristan, Melissa J Repine, Alexandro Gianforcaro, Rebecca B Hasley, Saad Feroz, Jessica M Rupp, Jumana Al-Baghli, Maria L Pacella, Brian P Suffoletto, Clifton W Callaway
BACKGROUND: Refining and individualizing treatment of acute pain in the emergency department (ED) is a high priority, given that painful complaints are the most common reasons for ED visits. Few tools exist to objectively measure pain perception in the ED setting. We speculated that variation in perception of fixed painful stimuli would explain individual variation in reported pain and response to treatment among ED patients. MATERIALS AND METHODS: In three studies, we 1) describe performance characteristics of brief quantitative sensory testing (QST) in 50 healthy volunteers, 2) test effects of 10 mg oxycodone versus placebo on QST measures in 18 healthy volunteers, and 3) measure interindividual differences in nociception and treatment responses in 198 ED patients with a painful complaint during ED treatment...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579821/opioid-analgesics-related-pharmacokinetic-drug-interactions-from-the-perspectives-of-evidence-based-on-randomized-controlled-trials-and-clinical-risk-management
#14
REVIEW
Xiu-Qin Feng, Ling-Ling Zhu, Quan Zhou
BACKGROUND: Multimorbidity results in complex polypharmacy which may bear a risk of drug interactions. A better understanding of opioid analgesics combination therapy used for pain management could help warrant medication safety, efficacy, and economic relevance. Until now there has been no review summarizing the opioid analgesics-related pharmacokinetic drug interactions from the perspective of evidence based on randomized controlled trials (RCTs). METHOD: A literature search was performed using PubMed, MEDLINE, and the Cochrane Library, using a PRISMA flowchart...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579820/cannabis-and-intractable-chronic-pain-an-explorative-retrospective-analysis-of-italian-cohort-of-614-patients
#15
Guido Fanelli, Giuliano De Carolis, Claudio Leonardi, Adele Longobardi, Ennio Sarli, Massimo Allegri, Michael E Schatman
BACKGROUND: Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, the Italian government authorized the use of cannabis to treat several diseases, including chronic pain generally, spasticity in multiple sclerosis, cachexia and anorexia among AIDS and cancer patients, glaucoma, Tourette syndrome, and certain types of epilepsy...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579819/outcomes-and-prognostic-variables-of-radiofrequency-zygapophyseal-joint-neurotomy-in-utah-workers-compensation-patients
#16
Tyler J Christensen, M Scott DeBerard, Anthony J Wheeler
PURPOSE: The prevalence of radiofrequency zygapophyseal joint neurotomy (RFN) has increased substantially across the past decade. Limited research exists that has examined pre-procedure predictors of RFN outcomes, particularly within workers' compensation populations. The purpose of this study was to determine if pre-procedure biopsychosocial variables are predictive of outcomes in a cohort of compensated Utah patients who have undergone RFN. PATIENTS AND METHODS: This was a retrospective cohort study consisting of a review of pre-procedure medical records and a telephone outcome survey...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28579818/healing-of-achilles-tendon-partial-tear-following-focused-shockwave-a-case-report-and-literature-review
#17
Yu-Chun Hsu, Wei-Ting Wu, Ke-Vin Chang, Der-Sheng Han, Li-Wei Chou
Achilles tendinopathy is a common cause of posterior heel pain and can progress to partial tendon tear without adequate treatment. Effects of traditional treatments vary, and many recent reports focus on the use of extracorporeal shockwave therapy (ESWT) for Achilles tendinopathy but not for Achilles tendon partial tear. Here, we report the case of a 64-year-old female suffering from severe left heel pain for half a year. All treatment and rehabilitation were less effective until ESWT was applied. Each course of focused shockwave therapy included 2500 shots with energy flux density from 0...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28572738/sleep-and-somatic-complaints-in-university-students
#18
Angelika A Schlarb, Merle Claßen, Sara M Hellmann, Claus Vögele, Marco D Gulewitsch
BACKGROUND: Sleep problems are common among university students. Poor sleep is associated with impaired daily functioning, increased risk of psychiatric symptoms, and somatic complaints such as pain. Previous results suggest that poor sleep exacerbates pain, which in turn negatively affects sleep. The purpose of the present study was to determine prevalence rates, comorbidity, and role of depression as a factor of moderating the relationship between sleep and physical complaints in German university students...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28553139/periarticular-dextrose-prolotherapy-instead-of-intra-articular-injection-for-pain-and-functional-improvement-in-knee-osteoarthritis
#19
Zahra Rezasoltani, Mehrdad Taheri, Morteza Kazempour Mofrad, Seyed Amir Mohajerani
BACKGROUND: Osteoarthritis (OA) is a degenerative disease that can lead to painful and dysfunctional joints. Prolotherapy involves using injections to produce functional restoration of the soft tissues of the joint. Intra-articular injections are controversial because of the introduction of needles into the articular capsule. OBJECTIVES: To compare the effect of periarticular versus intra-articular prolotherapy on pain and disability in patients with knee OA. STUDY DESIGN: Randomized double-blind controlled clinical trial...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28553138/children-s-and-adolescents-relationship-to-pain-during-cancer-treatment-a-preliminary-validation-of-the-pain-flexibility-scale-for-children
#20
Jenny Thorsell Cederberg, Sandra Weineland Strandskov, JoAnne Dahl, Gustaf Ljungman
OBJECTIVES: Children with cancer often suffer from pain. Pain is associated with psychological distress, which may amplify the pain experience. In chronic pain, it has been shown that psychological acceptance is helpful for both adults and children. For experimentally induced pain, interventions fostering psychological acceptance have been shown to predict increases in pain tolerance and reductions in pain intensity and discomfort of pain. A single subject study aiming to nurture psychological acceptance for children with cancer experiencing pain has shown promising results...
2017: Journal of Pain Research
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