Betina Idnay, Alex Butler, Yilu Fang, Ziran Li, Junghwan Lee, Casey Ta, Cong Liu, Brenda Ruotolo, Chi Yuan, Huanyao Chen, George Hripcsak, Elaine Larson, Chunhua Weng
Participant recruitment continues to be a challenge to the success of randomized controlled trials, resulting in increased costs, extended trial timelines and delayed treatment availability. Literature provides evidence that study design features (e.g., trial phase, study site involvement) and trial sponsor are significantly associated with recruitment success. Principal investigators oversee the conduct of clinical trials, including recruitment. Through a cross-sectional survey and a thematic analysis of free-text responses, we assessed the perceptions of sixteen principal investigators regarding success factors for participant recruitment...
2023: AMIA Summits on Translational Science Proceedings