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Journal of Clinical Medicine Research

Hidekatsu Yanai, Sumie Moriyama
No abstract text is available yet for this article.
October 2018: Journal of Clinical Medicine Research
Swapnil Patel, Mohammad A Hossain, Firas Ajam, Mayurkumar Patel, Mihir Nakrani, Jasmine Patel, Alsadiq Alhillan, Mohamed Hammoda, Anas Alrefaee, Michael Levitt, Arif Asif
Acute kidney injury (AKI) due to an acute interstitial nephritis (AIN) is common and can lead to increased morbidity and mortality. Medications such as antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), proton pump inhibitors (PPI) and rifampin are common offending agents. Anticoagulant-associated AIN is more frequently reported with the use of warfarin; however, only few case reports have reported an association with the use of novel oral anticoagulants (NOACs). Herein, we report the case of a 59-year-old male who developed AKI after initiating dabigatran for the treatment of atrial fibrillation...
October 2018: Journal of Clinical Medicine Research
Huzaif Qaisar, Mohammad A Hossain, Monika Akula, Jennifer Cheng, Mayurkumar Patel, Zheng Min, Halyna Kuzyshyn, Michael Levitt, Shana M Coley, Arif Asif
While methimazole (MMI) is the first line treatment for hyperthyroidism, this medication is not devoid of adverse effects. In this article, we present a 70-year-old male who admitted the hospital with right lower extremity pain and rash. The patient was recently treated with MMI for hyperthyroidism. Imaging studies revealed bilateral renal and splenic infarcts along with thrombosis of popliteal artery. Laboratory data revealed hematuria and proteinuria with positive (MPO), anti-proteinase-3 (PR3) and anti-cardiolipin IgG antibodies...
October 2018: Journal of Clinical Medicine Research
Amelia Bai, Ling Lan, Karl Poon, Varghese Pynadath Joseph, Rachael O'Rourke, Khurrum Aftab
Pulmonary artery pseudoaneurysm is a dangerous pathology often missed as a differential and on imaging. With a 50% mortality rate early detection and intervention are critical to patient outcome, rendering diagnosis based on clinical grounds to be of paramount importance. A high index of suspicion should be placed on patients presenting with unprovoked hemoptysis, hemorrhage or hemothorax. Knowledge of the common causes of pulmonary artery pseudoaneurysms is also important; however, it is integral to note spontaneous occurrences in patients with no known risk factors...
October 2018: Journal of Clinical Medicine Research
Junko Nakanishi, Yasunori Suematsu, Tadaaki Arimura, Takashi Kuwano, Yuhei Shiga, Ken Kitajima, Natsumi Morito, Takanobu Nii, Keijiro Saku, Shin-Ichiro Miura
Background: We analyzed what kind of lifestyle modification first-year university students need based on the results of a health-consciousness survey conducted in first-year students immediately after they entered a university. Methods: This population-based cross-sectional study used a "questionnaire survey on lifestyle and health for promoting health" conducted in Japan in 2015. From among an initial pool of 3,912 students, we excluded 314 due to insufficient data...
October 2018: Journal of Clinical Medicine Research
Kazuhiro Katayama, Toshihiro Imai, Yutaro Abe, Tadatoshi Nawa, Noboru Maeda, Katsuyuki Nakanishi, Hiroshi Wada, Keisuke Fukui, Yuri Ito, Isao Yokota, Kazuyoshi Ohkawa
Background: To determine whether response to transarterial chemoembolization (TACE) predicts survival and to identify pretreatment factors associated with TACE response and prognosis. Methods: Between April and September 2010, 50 patients underwent TACE for hepatocellular carcinoma. Response to TACE was assessed using post-treatment computed tomography (CT) and magnetic resonance imaging (MRI) scans and tumor marker levels and classified as Response Poor (P) and Non-poor (NP)...
October 2018: Journal of Clinical Medicine Research
Ming Y Lim, Ricardo Yamada, Marcelo Guimaraes, Charles S Greenberg
Background: There is a wide variability in practice patterns on the use of inferior vena cava filters (IVCFs) among institutions, which is likely due to contrasting indication guidelines published by different professional societies. The aim of the present study is to report our healthcare system use of IVCF to: 1) determine practice patterns, 2) determine factors that may predict IVCF retrieval and 3) identify areas for improvement. Methods: A retrospective review of 180 consecutive IVCF placement performed between July 2014 and December 2015 was conducted...
October 2018: Journal of Clinical Medicine Research
Lidong Hu, Si-Cheng Dai, Xiaojun Luan, Jingsong Chen, Anthony Cannavicci
Diabetes mellitus (DM) is a chronic, multifactorial metabolic disease whereby insulin deficiency or resistance results in hyperglycemia. Endothelial cells (ECs) form the innermost layer of the blood vessel and produce and release a variety of vasoactive substances and growth factors to regulate vascular homeostasis and angiogenesis. Hyperglycemia and insulin resistance can cause endothelial dysfunction, leading to vascular complications such as coronary artery disease, peripheral arterial disease, diabetic nephropathy, neuropathy and retinopathy...
October 2018: Journal of Clinical Medicine Research
Fotios S Fousekis, Vasileios I Theopistos, Konstantinos H Katsanos, Dimitrios K Christodoulou
Inflammatory bowel disease (IBD) is a multisystemic disease, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases in Crohn's disease and ulcerative colitis is more frequent compared to the general population. Pancreatic manifestations in IBD include a wide heterogenic group of disorders and abnormalities of the pancreas and range from mild self-limited diseases to severe disorders. Acute pancreatitis, chronic pancreatitis, autoimmune pancreatitis, pancreatic autoantibodies, exocrine pancreatic insufficiency and asymptomatic imaging and laboratory abnormalities are included in related-IBD pancreatic manifestations...
October 2018: Journal of Clinical Medicine Research
Masaya Sakamoto
It has become possible to measure blood glucose levels continuously from 24 h to approximately 2 weeks due to the recent development of relevant devices such as continuous glucose monitoring and flash glucose monitoring systems. This has enabled not only medical professionals but also patients to monitor details of glycemic variability (GV) which was not possible in the past. Details of GV for both short and intermediate periods can now be obtained, and it is important in patient care to appropriately evaluate the data obtained...
October 2018: Journal of Clinical Medicine Research
Renato De Vecchis, Carmelina Ariano, Angelos Rigopoulos, Michel Noutsias
No abstract text is available yet for this article.
September 2018: Journal of Clinical Medicine Research
Hisayuki Katsuyama, Hidetaka Hamasaki, Hidekatsu Yanai
No abstract text is available yet for this article.
September 2018: Journal of Clinical Medicine Research
Yana Kogan, Nizar Elias, Alona Paz, Majed Odeh
Delirium is considered as the most common complication afflicting hospitalized elderly patients, accompanied by high morbidity and mortality rate; and despite its high prevalence, it often remains unrecognized. Drug-induced delirium is a well-known entity with sedatives, narcotics and anticholinergics most often implicated in its causation. Delirium attributed to antibiotics, mainly cephalosporins and macrolids, has been infrequently reported, and until yet only seven cases of levofloxacin-induced delirium have been described in the medical literature...
September 2018: Journal of Clinical Medicine Research
Beau M Bailey, Kenneth S Ramos, Alice Johnson, Charlene Mitchell
Systemic lupus erythematosus (SLE) is an autoimmune disease known to affect a variety of organ systems. Patients with SLE are more prone to developing common infections that can mimic the complications of SLE. As such, it is essential to differentiate complications of SLE from infection to ensure appropriate management and to improve morbidity and mortality of this patient population. Here we present a 24-year-old, Hispanic male, with SLE complicated by dialysis-dependent end-stage renal disease and dilated cardiomyopathy...
September 2018: Journal of Clinical Medicine Research
Makoto Ito, Emiko Seo, Takami Maeno, Ryoko Ogawa, Tetsuhiro Maeno
Background: Depression among medical residents is a critical issue. The early detection of depression and provision of appropriate care is necessary for fostering healthy conditions during clinical training. To investigate whether Sense of Coherence (SOC), an indicator of stress coping ability, could be a predictor of depression 2 years after the start of clinical training, we conducted a national longitudinal study. Methods: We distributed self-administered questionnaires to residents in 251 postgraduate educational hospitals just before the start of their clinical training...
September 2018: Journal of Clinical Medicine Research
Abdulbari Bener, Yasar Ozdenkaya, Abdulla O A A Al-Hamaq, Cem Cahit Barisik, Mustafa Ozturk
Background: The aim of this study was to investigate the relationship between vitamin D deficiency and thyroid diseases among type 2 diabetes mellitus (T2DM) patients. Methods: This was a cohort case and control study, 546 T2DM patients and 546 control study participants were enrolled, aged between 25 and 65 years. The subjects were also investigated for fasting blood glucose levels (FBG), post prandial glucose (PPG,) glycosylated hemoglobin (HbA1c), thyroid stimulating hormone (TSH), T3, T4, and presence of other comorbid conditions...
September 2018: Journal of Clinical Medicine Research
Marilena Greco, Claudio Palumbo, Fernando Sicuro, Giambattista Lobreglio
Background: Sepsis is currently defined as a life-threatening organ dysfunction caused by a deregulated host response to infection. There is increasing evidence that the endothelium plays a crucial and pathogenic role in sepsis. Profound alterations of the endothelium associated with sepsis include increased leucocytes adhesions, shift to a procoagulant state, vasodilatation, altered barrier function with more permeable capillaries and tissue edema. The vascular endothelial growth factor (VEGF) pathway is involved in the control of microvascular permeability and has been involved in the pathogenesis of conditions associated with endothelial barrier disruption such as sepsis...
September 2018: Journal of Clinical Medicine Research
Cosme Alvarado-Esquivel
Background: Very little is known about suicide attempts in middle-aged women in Mexico. The aims of this study were to determine: 1) the prevalence of suicidal ideation and suicide attempts in middle-aged women in Durango City, Mexico; and 2) the suicide attempt prevalence association with the sociodemographic, clinical, and behavioral characteristics of the women studied. Methods: Through a cross-sectional study, 395 middle-aged women were surveyed. Suicidal ideation, suicide attempt data, and the characteristics of the women were obtained with the aid of a questionnaire...
September 2018: Journal of Clinical Medicine Research
Maria Vadala, Christian Testa, Laura Coda, Stefania Angioletti, Rosanna Giuberti, Carmen Laurino, Beniamino Palmieri
Background: The vulvovestibular syndrome (VVS) is a chronic, inflammatory, multifactorial, chronic inflammation of the female urogenital access. Methods: The aim of this anecdotal, observational, retrospective, case-control study was to comparatively evaluate the most common bacterial strains ( Lactobacillus spp. , Klebsiella spp. , Gardnerella spp. , and Streptococcus spp. ) and fungi ( Candida spp. , Pennicillum spp ., and Aspergillus spp. ) in vulvodinic women, and in women without gynecological symptoms (control group)...
September 2018: Journal of Clinical Medicine Research
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