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Journal of Clinical Medicine Research

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https://www.readbyqxmd.com/read/28392867/is-an-increase-in-serum-magnesium-one-of-the-causes-of-cardiovascular-events-reduction-in-the-empa-reg-outcome-study
#1
Tatsuo Yanagawa
No abstract text is available yet for this article.
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392866/what-properties-of-sodium-glucose-cotransporter-2-inhibitors-determine-the-improvement-in-hemoglobin-a1c-and-body-weight
#2
Hidekatsu Yanai, Mariko Hakoshima, Hiroki Adachi
No abstract text is available yet for this article.
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392865/cardio-ankle-vascular-index-and-c-reactive-protein-are-useful-parameters-for-identification-of-ischemic-heart-disease-in-acute-heart-failure-patients
#3
Shunsuke Kiuchi, Shinji Hisatake, Takayuki Kabuki, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Takanori Ikeda
BACKGROUND: The most common cause of heart failure (HF) is ischemic heart disease (IHD). Evaluation of IHD with non-invasive examinations is useful for the treatment of HF, and cardio-ankle vascular index (CAVI) is a good parameter for detecting systemic arteriosclerosis. However, the relationship between IHD and CAVI in acute HF (AHF) patients is still unclear. Therefore, we investigated the effect of non-invasive examinations, including CAVI to detect IHD. METHODS: We studied 53 consecutive patients (average age of 66...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392864/traumatic-abdominal-solid-organ-injury-patients-might-benefit-from-thromboelastography-guided-blood-component-therapy
#4
Hao Wang, Richard D Robinson, Jessica L Phillips, Andrew Ryon, Scott Simpson, Jonathan R Ford, Johnbosco Umejiego, Therese M Duane, Bradley Putty, Nestor R Zenarosa
BACKGROUND: Thromboelastography (TEG) has been utilized for the guidance of blood component therapy (BCT). We aimed to investigate the association between emergent TEG-guided BCT and clinical outcomes in patients with traumatic abdominal solid organ (liver and/or spleen) injuries. METHODS: A single center retrospective study of patients who sustained traumatic liver and/or spleen injuries receiving emergent BCT was conducted. TEG was ordered in all these patients...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392863/efficacy-of-intravenous-administration-of-landiolol-in-patients-with-acute-heart-failure-and-supraventricular-tachyarrhythmia
#5
Shunsuke Kiuchi, Hiroto Aikawa, Shinji Hisatake, Takayuki Kabuki, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Takanori Ikeda
BACKGROUND: Patients with acute heart failure (HF) complicated by supraventricular tachyarrhythmia (SVT) often receive continuous intravenous infusion of landiolol or diltiazem for rate control. It is unclear whether the interval from initiation of infusion to commencement of oral beta-blocker (BB) therapy differs for these two drugs. METHODS: From January 2013 to July 2015, 94 consecutive patients were hospitalized for acute HF complicated by SVT. After 35 patients were excluded, the remaining 59 were divided into groups treated with diltiazem or landiolol...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392862/role-of-lncrna-af085935-il-10-and-il-17-in-rheumatoid-arthritis-patients-with-chronic-hepatitis-c
#6
Dina Sabry, Azza Elamir, Rania Hosny Mahmoud, Ahmed Ali Abdelaziz, Wael Fathy
BACKGROUND: The current study aimed at testing the effect of corticosteroid therapy on serum levels of interleukin-10 (IL-10) and IL-17 as well as lncRNA-AF085935 in patients of rheumatoid arthritis (RA) associated with hepatitis C virus (HCV) and evaluating the usefulness of using these parameters to predict the therapeutic efficacy of steroids in these patients. METHODS: Thirty healthy control subjects and 65 chronic HCV patients with RA were included in our study...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392861/reported-exercise-related-respiratory-symptoms-and-exercise-induced-bronchoconstriction-in-asthmatic-children
#7
Demet Inci, Refoel Guggenheim, Derya Ufuk Altintas, Johannes H Wildhaber, Alexander Moeller
BACKGROUND: Unlimited physical activity is one of the key issues of asthma control and management. We investigated how reliable reported exercise-related respiratory symptoms (ERRS) are in predicting exercise-induced bronchoconstriction (EIB) in asthmatic children. METHODS: In this prospective study, 179 asthmatic children aged 7 - 15 years were asked for specific questions on respiratory symptoms related to exercise and allocated into two groups according to whether they complained about symptoms...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392860/the-effect-of-tofogliflozin-treatment-on-postprandial-glucose-and-lipid-metabolism-in-japanese-men-with-type-2-diabetes-a-pilot-study
#8
Hirokazu Kakuda, Junji Kobayashi, Masaru Sakurai, Masahiro Kakuda, Noboru Takekoshi
BACKGROUND: Postprandial hyperglycemia and hyperlipidemia are highly related to the development of atherosclerosis. Sodium/glucose cotransporter-2 (SGLT2) inhibitors have attracted attention as a new class of anti-diabetic agents for the treatment of type 2 diabetes. We investigated the effect of tofogliflozin on postprandial glucose and lipid metabolism in Japanese male patients with type 2 diabetes. METHODS: Ten Japanese men with type 2 diabetes (average age 66...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392859/whole-body-vibration-training-during-a-low-frequency-outpatient-exercise-training-program-in-chronic-obstructive-pulmonary-disease-patients-a-randomized-controlled-trial
#9
Marc Spielmanns, Rainer Gloeckl, Jana Marie Gropp, Christoph Nell, Andreas Rembert Koczulla, Tobias Boeselt, Jan Hendrik Storre, Wolfram Windisch
BACKGROUND: The aim of the study was to investigate whether whole-body vibration training (WBVT) can be applied beneficially within an outpatient low frequency exercise program. METHODS: In a prospective, controlled, randomized study, WBVT effectiveness and safety were investigated in COPD stage II-IV patients undergoing a 3-month training program. Participants took part in a 90-min circuit training once a week. On top patients were randomized to either perform squats with WBVT, or without (conventional training group (CTG))...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392858/effect-of-metformin-on-different-non-diabetes-related-conditions-a-special-focus-on-malignant-conditions-review-of-literature
#10
REVIEW
Elamin Abdelgadir, Razan Ali, Fauzia Rashid, Alaaeldin Bashier
Metformin has been proven to be one of the most safe and effective antihyperglycemic agents. Through more than six decades of metformin use, it became the most studied hypoglycemic agent; through these studies, it showed a marvelous non-glycemic related effect. These effects include modulation of different points of cancer timeline, weight reduction, cardiovascular health, thyroid diseases, polycystic ovaries disease and many other medical conditions. The aim of this review was to assess the effect of metformin on non-diabetes related medical diseases...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392857/gender-disparities-in-osteoporosis
#11
REVIEW
Khaled A Alswat
Osteoporosis is a growing health concern worldwide and its complications are as prevalent as other common chronic disease complications such as hypertension and diabetes. In this review, we will discuss the role of gender in osteoporosis, especially related to peak bone mass and maturation, rate of annual bone loss, screening, prevalence of osteoporosis and its related fractures, mortality after osteoporosis-related fracture, fracture risk predication using different technologies and the impact of gender on osteoporosis management...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392856/impact-of-physical-activity-in-cardiovascular-and-musculoskeletal-health-can-motion-be-medicine
#12
REVIEW
Gannon L Curtis, Morad Chughtai, Anton Khlopas, Jared M Newman, Rafay Khan, Shervin Shaffiy, Ali Nadhim, Anil Bhave, Michael A Mont
Physical activity is a well-known therapeutic tool for various types of medical conditions, including vasculopathic diseases such as coronary artery disease, stroke, type 2 diabetes, and obesity. Additionally, increased physical activity has been proposed as a therapy to improve musculoskeletal health; however, there are conflicting reports about physical activity potentially leading to degenerative musculoskeletal disease, especially osteoarthritis (OA). Additionally, although physical activity is known to have its benefits, it is unclear as to what amount of physical activity is the most advantageous...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270898/current-metabolic-status-affects-urinary-liver-type-fatty-acid-binding-protein-in-normoalbuminuric-patients-with-type-2-diabetes
#13
Hiroyuki Ito, Hitomi Yamashita, Mina Nakashima, Akifusa Takaki, Chiduko Yukawa, Suzuko Matsumoto, Takashi Omoto, Masahiro Shinozaki, Shinya Nishio, Mariko Abe, Shinichi Antoku, Mizuo Mifune, Michiko Togane
BACKGROUND: We aimed to study the association between urinary liver-type fatty acid-binding protein (L-FABP), a biomarker of tubulointerstitial injury, and the clinical characteristics of normoalbuminuric and albuminuric patients with type 2 diabetes in order to detect the factors affecting urinary L-FABP. METHODS: Urinary L-FABP levels were measured in 788 patients with type 2 diabetes and again in 666 patients at 6 months after the initial measurement. The association between the urinary L-FABP level and the clinical parameters was investigated in a retrospective cross-sectional study and a subsequent observation...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270897/determinants-of-glycated-hemoglobin-in-subjects-with-impaired-glucose-tolerance-subanalysis-of-the-japan-diabetes-prevention-program
#14
Naoki Sakane, Juichi Sato, Kazuyo Tsushita, Satoru Tsujii, Kazuhiko Kotani, Makoto Tominaga, Shoji Kawazu, Yuzo Sato, Takeshi Usui, Isao Kamae, Toshihide Yoshida, Yutaka Kiyohara, Shigeaki Sato, Kokoro Tsuzaki, Shinsuke Nirengi, Kaoru Takahashi, Hideshi Kuzuya, Jdpp Research Group
BACKGROUND: Limited evidence is available about the relationship of lifestyle factors with glycated hemoglobin (HbA1c) in subjects with impaired glucose tolerance. The aim of study was to identify such determinant factors of HbA1c in subjects with impaired glucose tolerance. METHODS: This cross-sectional study included 121 men and 124 women with impaired glucose tolerance, who were diagnosed based on a 75-g oral glucose tolerance test. Demographic and biochemical parameters, including the body mass index (BMI), fasting plasma glucose (FPG), 2-h post-load glucose (2-h PG), and HbA1c, were measured...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270896/left-ventricular-diastolic-function-assessment-of-a-heterogeneous-cohort-of-pulmonary-arterial-hypertension-patients
#15
Dagmar F Hernandez-Suarez, Francisco R Lopez Menendez, Denada Palm, Angel Lopez-Candales
BACKGROUND: Pulmonary arterial hypertension (PAH) is known to trigger right ventricular (RV) remodeling that might compromise left ventricular (LV) filling due to inter-ventricular interdependence. In this study, we aimed to examine standard echocardiographic measurements of LV diastolic function in PAH patients. METHODS: In this retrospective study, we identified clinical as well as complete echocardiographic data from 128 chronic PAH patients to fully assess LV diastolic dysfunction (LVDD) using standard recommended Doppler guidelines...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270895/significance-of-cardiac-rehabilitation-on-visit-to-visit-variability-of-blood-pressure-in-patients-with-cardiovascular-disease-in-a-12-month-follow-up
#16
Toshihisa Ishida, Shin-Ichiro Miura, Kanta Fujimi, Makito Futami, Yoko Ueda, Takashi Ueda, Tadaaki Arimura, Rie Koyoshi, Yuhei Shiga, Ken Kitajima, Keijiro Saku
BACKGROUND: Visit-to-visit variability (VVV) in blood pressure (BP) has been shown to be a strong predictor of cardiovascular disease (CVD). However, the long-term effect of comprehensive cardiac rehabilitation (CR) with exercise training on VVV in BP has not yet been established. Therefore, we evaluated the long-term effects of CR on VVV in BP in patients with CVD. METHODS: Twenty-two CVD patients in a 12-month CR program who had at least six clinic visits per month to measure BP were enrolled...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270894/the-effect-of-individualized-versus-standardized-parenteral-nutrition-on-body-weight-in-very-preterm-infants
#17
Vincent H M Evering, Peter Andriessen, Carola E P M Duijsters, Jeroen Brogtrop, Luc J J Derijks
BACKGROUND: This study was designed to evaluate whether standardizing total parenteral nutrition (TPN) is at least non-inferior to TPN with individualized composition in premature infants with a gestational age (GA) < 32 weeks. METHODS: In this retrospective cohort study, all preterm born in or transferred to Maxima Medical Center (MMC) within 24 hours after birth with a GA < 32 weeks were included. The individualized group (2011) was compared to the partially standardized group (2012) and completely standardized group (2014) consequently...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270893/association-of-whole-blood-viscosity-with-metabolic-syndrome-in-type-2-diabetic-patients-independent-association-with-post-breakfast-triglyceridemia
#18
Satomi Minato, Akiko Takenouchi, Junko Uchida, Ayaka Tsuboi, Miki Kurata, Keisuke Fukuo, Tsutomu Kazumi
BACKGROUND: Associations of whole blood viscosity (WBV) with metabolic syndrome (MS) have not been extensively studied in patients with type 2 diabetes. METHODS: Intrapersonal means of 12 measurements of waist circumference, blood pressure (BP) and high-density lipoprotein cholesterol and those of six measurements of fasting and post-breakfast triglycerides (TG) during 12 months were calculated in a cohort of 168 patients with type 2 diabetes. Based on these means, MS was diagnosed according to the modified National Cholesterol Education Program Adult Treatment Panel III criteria with the Asian definition of abdominal obesity...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270892/molecular-analysis-of-factor-viii-and-factor-ix-genes-in-hemophilia-patients-identification-of-novel-mutations-and-molecular-dynamics-studies
#19
Faisal A Al-Allaf, Mohiuddin M Taher, Zainularifeen Abduljaleel, Abdellatif Bouazzaoui, Mohammed Athar, Neda M Bogari, Halah A Abalkhail, Tarek Ma Owaidah
BACKGROUND: Hemophilias A and B are X-linked bleeding disorders caused by mutations in the factor VIII and factor IX genes, respectively. Our objective was to identify the spectrum of mutations of the factor VIII and factor IX genes in Saudi Arabian population and determine the genotype and phenotype correlations by molecular dynamics (MD) simulation. METHODS: For genotyping, blood samples from Saudi Arabian patients were collected, and the genomic DNA was amplified, and then sequenced by Sanger method...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28270891/visit-to-visit-low-density-lipoprotein-cholesterol-variability-is-an-independent-determinant-of-carotid-intima-media-thickness-in-patients-with-type-2-diabetes
#20
Akiko Takenouchi, Ayaka Tsuboi, Kaori Kitaoka, Satomi Minato, Miki Kurata, Keisuke Fukuo, Tsutomu Kazumi
BACKGROUND: Studies demonstrated that visit-to-visit variability in low-density lipoprotein cholesterol (LDLC) is an independent predictor of cardiovascular events in subjects with coronary artery disease. Whether visit-to-visit variability in LDLC levels affects subclinical atherosclerosis is unknown. This study sought to evaluate the role of visit-to-visit variability in LDLC levels on subclinical atherosclerosis. METHODS: We evaluated 162 type 2 diabetic patients with measurement of carotid intima-media thickness (IMT)...
April 2017: Journal of Clinical Medicine Research
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