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Journal of Clinical Medicine Research

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https://www.readbyqxmd.com/read/28611868/gastrointestinal-tract-amyloidosis-presenting-with-pneumatosis-intestinalis
#1
Vikram Raghunathan, David Louis, Baldeep Wirk
Pneumatosis intestinalis is a radiographic finding of gas pockets within the bowel wall. It can be associated with a range of diagnoses, but the most life-threatening causes are mesenteric ischemia, bowel necrosis, and bowel obstruction. Here we present the case of a patient with multiple myeloma who had pneumatosis intestinalis due to gastrointestinal amyloidosis, which is a rare manifestation of systemic amyloid disease. The patient had both transthyretin (ATTR) amyloidosis and acquired apolipoprotein serum amyloid A (AA) amyloidosis that are not usually seen in conjunction with multiple myeloma, which is most commonly associated with light-chain (AL) amyloidosis...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611867/a-comparative-study-of-the-trends-of-imported-dengue-cases-in-korea-and-japan-2011-2015
#2
Shinichiro Miki, Won-Chang Lee, Myeong-Jin Lee
BACKGROUND: Dengue is a mosquito-borne febrile disease that represents a major public health problem in tropical and subtropical areas. Even though Korea and Japan are not the regions where dengue is epidemic, there have been many imported cases in both countries, and in increasing numbers. A better understanding of the characteristics of the prevalence of dengue and the recent trends in these neighboring countries may provide information to promote improvement and control strategies for both...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611866/association-of-cognitive-impairment-in-patients-on-3-hydroxy-3-methyl-glutaryl-coa-reductase-inhibitors
#3
Satyajeet Roy, Joshua Louis Weinstock, Allyse Sachiko Ishino, Jefferson Felix Benites, Samantha Rachel Pop, Christopher David Perez, Edvard Adrian Gumbs, Jennifer Ann Rosenbaum, Mary Kate Roccato, Hely Shah, Gabriela Contino, Krystal Hunter
BACKGROUND: Atherosclerotic cardiovascular diseases are the leading cause of death in the United States. A reduction in cholesterol with 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statin) significantly reduces mortality and morbidity. Statins may be associated with cognitive impairment or dementia. Our aim was to study the association of cognitive impairment or dementia in patients who were on a statin. METHODS: Electronic medical records of 3,500 adult patients in our suburban internal medicine office were reviewed...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611865/dietary-modification-trial-in-community-dwelling-japanese-elderly-a-pilot-study
#4
Chika Momoki, Taeko Tsuji, Yukina Shikata, Hana Urade, Hideki Morimoto, Shinya Nakajima, Daiki Habu
BACKGROUND: This study examined the effects of 6-month nutrition education programs for community-dwelling elderly. METHODS: This study enrolled 50 community-dwelling elderly who regularly visit outpatient clinics. The programs had three goals: salt reduction, increase in dietary fiber, and adequate protein intake. Since it would be difficult for elderly to achieve all goals concurrently, a single goal was chosen by participants themselves. Anthropometric measurements, blood sampling, and assessment of dietary intake were performed at baseline, 3 months, and 6 months...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611864/entamoeba-histolytica-infection-in-female-sex-workers-a-matched-case-control-study-in-durango-mexico
#5
Cosme Alvarado-Esquivel, Luis Francisco Sanchez-Anguiano, Jesus Hernandez-Tinoco, Sergio Estrada-Martinez, Alma Rosa Perez-Alamos, Agar Ramos-Nevarez, Sandra Margarita Cerrillo-Soto, Carlos Alberto Guido-Arreola
BACKGROUND: Infection with Entamoeba histolytica (E. histolytica) can be potentially transmitted by sexual contact. The seroepidemiology of E. histolytica in female sex workers has not been studied. The aim of the study was to determine whether E. histolytica is associated with the occupation of female sex work. In addition, the correlates of E. histolytica seroprevalence in female sex workers were also investigated. METHODS: We performed an age- and gender-matched case-control study of 187 female sex workers and 374 women without sex work...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611863/effect-of-azilsartan-on-day-to-day-variability-in-home-blood-pressure-a-prospective-multicenter-clinical-trial
#6
Toru Miyoshi, Ryoji Suetsuna, Naoto Tokunaga, Masayasu Kusaka, Ryuichiro Tsuzaki, Kazuya Koten, Kohno Kunihisa, Hiroshi Ito
BACKGROUND: The blood pressure variability (BPV) such as visit-to-visit, day-by-day, and ambulatory BPV has been also shown to be a risk of future cardiovascular events. However, the effects of antihypertensive therapy on BPV remain unclear. The purpose of this study was to evaluate the effect of azilsartan after switching from another angiotensin II receptor blocker (ARB) on day-to-day BPV in home BP monitoring. METHODS: This prospective, multicenter, open-labeled, single-arm study included 28 patients undergoing treatment with an ARB, which was switched to azilsartan after enrollment...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611862/mini-laparoscopic-versus-conventional-laparoscopic-surgery-for-benign-adnexal-masses
#7
Servet Gencdal, Huseyin Aydogmus, Serpil Aydogmus, Zafer Kolsuz, Sefa Kelekci
BACKGROUND: Minimally invasive endoscopic surgery has become an acceptable method for gynecologic indications for more than 20 years. We aimed to compare clinical and surgical outcomes between mini-laparoscopic surgery (MLS) and conventional laparoscopic surgery (CLS) for benign adnexal masses. As far as we know, no comparative study exists between these two minimal invasive procedures. METHODS: During the period between January 2014 and December 2016, a total number of 132 laparoscopic surgeries were performed for bening adnexal masses in our clinic...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611861/effects-of-six-kinds-of-sodium-glucose-cotransporter-2-inhibitors-on-metabolic-parameters-and-summarized-effect-and-its-correlations-with-baseline-data
#8
Hidekatsu Yanai, Mariko Hakoshima, Hiroki Adachi, Akiko Kawaguchi, Yoko Waragai, Tadanao Harigae, Yoshinori Masui, Kouki Kakuta, Hidetaka Hamasaki, Hisayuki Katsuyama, Tomoko Kaga, Akahito Sako
BACKGROUND: Sodium-glucose cotransporter 2 inhibitor (SGLT2i) blocks reabsorption of glucose by inhibiting SGLT2 in kidney, promotes the renal excretion of glucose and improves blood glucose control without requiring insulin secretion. Anti-atherosclerotic effects of SGLT2is have not been fully elucidated until today. METHODS: We retrospectively picked up patients with type 2 diabetes who had been continuously prescribed SGLT2i for 3 months or more between April 2014 and December 2016 by a chart-based analysis, and compared metabolic parameters including coronary risk factors before the SGLT2i treatment with the data at 3 and 6 months after the SGLT2i treatment started...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611860/renal-function-and-outcomes-with-use-of-left-ventricular-assist-device-implantation-and-inotropes-in-end-stage-heart-failure-a-retrospective-single-center-study
#9
Sean Verma, Emmanuel Bassily, Shane Leighton, Rahul Mhaskar, Igor Sunjic, Angel Martin, Nancy Rihana, Tambi Jarmi, Claude Bassil
BACKGROUND: Left ventricular assist device (LVAD) and inotrope therapy serve as a bridge to transplant (BTT) or as destination therapy in patients who are not heart transplant candidates. End-stage heart failure patients often have impaired renal function, and renal outcomes after LVAD therapy versus inotrope therapy have not been evaluated. METHODS: In this study, 169 patients with continuous flow LVAD therapy and 20 patients with continuous intravenous inotrope therapy were analyzed...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611859/ipragliflozin-improves-glycemic-control-and-decreases-body-fat-in-patients-with-type-2-diabetes-mellitus
#10
Takehiro Kawata, Takashi Iizuka, Kotaro Iemitsu, Masahiro Takihata, Masahiko Takai, Shigeru Nakajima, Nobuaki Minami, Shinichi Umezawa, Akira Kanamori, Hiroshi Takeda, Shogo Ito, Taisuke Kikuchi, Hikaru Amemiya, Mizuki Kaneshiro, Atsuko Mokubo, Tetsuo Takuma, Hideo Machimura, Keiji Tanaka, Taro Asakura, Akira Kubota, Sachio Aoyanagi, Kazuhiko Hoshino, Masashi Ishikawa, Yoko Matsuzawa, Mitsuo Obana, Nobuo Sasai, Hideaki Kaneshige, Fuyuki Minagawa, Tatsuya Saito, Kazuaki Shinoda, Masaaki Miyakawa, Yasushi Tanaka, Yasuo Terauchi, Ikuro Matsuba
BACKGROUND: Ipragliflozin, a sodium-glucose transporter 2 inhibitor, was administered to patients with type 2 diabetes mellitus for 24 weeks to evaluate its effect on glycemic control and body composition. METHODS: This was an investigator-initiated multicenter prospective intervention study in which ipragliflozin (50 mg) was administered once daily and glycemic control, blood pressure, body weight (BW), body composition (measured by a biological impedance method), the lipid profile, and adverse events were evaluated after 4, 12, and 24 weeks of treatment...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611858/impact-of-hemorheology-assessed-by-the-microchannel-method-on-pulsatility-index-of-the-common-carotid-artery-in-patients-with-type-2-diabetes-mellitus
#11
Takashi Hitsumoto
BACKGROUND: Type 2 diabetes mellitus is known to be closely associated with the risk of ischemic stroke. Recent clinical studies have reported that a high pulsatility index (PI) of the cerebral or carotid artery, which is estimated by ultrasonography, also reflects a risk of ischemic stroke. This cross-sectional study aimed to clarify the impact of hemorheology assessed by the microchannel method on the PI of the common carotid artery (CCA) in patients with type 2 diabetes mellitus in terms of the primary prevention of ischemic stroke...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611857/chronic-achilles-tendon-rupture-reconstruction-using-the-lindholm-method-and-the-vulpius-method
#12
Firat Ozan, Fatih Dogar, Kaan Gurbuz, Yakup Ekinci, Semmi Koyuncu, Hazim Sekban
BACKGROUND: We investigated the clinical and functional outcomes of chronic Achilles tendon rupture reconstruction via the Lindholm technique and via the Vulpius' lengthening of the gastrocnemius. METHODS: We evaluated 15 patients with chronic Achilles tendon rupture (Lindholm technique in eight patients and primary repair with the Vulpius technique in seven patients). In the final follow-up, the Hooker scale was used to measure the ankle functional capacity in all patients...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611856/a-randomized-controlled-trial-of-vildagliptin-versus-alogliptin-effective-switch-from-sitagliptin-in-patients-with-type-2-diabetes
#13
Erina Shigematsu, Tadashi Yamakawa, Mari S Oba, Jun Suzuki, Jo Nagakura, Kazuaki Kadonosono, Yasuo Terauchi
BACKGROUND: We investigated the effects of vildagliptin or alogliptin on blood glucose and hemoglobin A1c (HbA1c) in patients with type 2 diabetes inadequately controlled by sitagliptin. METHODS: In a single-center open-label trial, 35 patients with inadequate glycemic control on sitagliptin therapy (50 mg once daily) were randomly switched to treatment with vildagliptin (50 mg twice daily) or alogliptin (25 mg once daily). After 12 weeks, patients who failed to achieve the target HbA1c level of < 7...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611855/variables-to-predict-nephrological-disease-in-general-and-glomerulonephritis-in-particular-in-patients-with-microhematuria
#14
Carsten Paul Bramlage, Manuel Wallbach, David Ellenberger, Cornelia Deutsch, Joan Minguet, Katherine Helen Smith, Johanna Stock, Alina Goninski, Peter Bramlage, Michael Koziolek, Gerhard Anton Mueller
BACKGROUND: Microhematuria (MH) is a symptom frequently leading to uncertainty as to when a nephrology referral is appropriate. Because MH may be indicative of severe kidney disorders, prompt diagnosis and potential treatment initiation can be important. We aimed to identify further variables that point at a nephrological cause, in particular of glomerulonephritis (GN), when MH is diagnosed. METHODS: A retrospective analysis of data acquired from patients attending a nephrology office due to MH was performed...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611854/arginine-asymmetric-dimethylarginine-ratio-in-colorectal-surgery
#15
Neli Ragina, Gabrielle Davis, Michael Doorly, Kyle Cologne, Anthony J Senagore
BACKGROUND: Asymmetric dimethylarginine (ADMA) is a naturally occurring amino acid that inhibits the effects of nitric oxide synthetases, producing considerable effects on the vascular system. Recent studies have suggested that increased ADMA is a major contributor to endothelial dysfunction, resulting in significant effects on cardiovascular and renal function. METHODS: The study sample consisted of five male and 11 female patients scheduled for elective laparoscopic colorectal surgery; patients were between 41 and 77 years of age...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28611853/an-unsettled-debate-about-the-potential-role-of-infection-in-pathogenesis-of-atherosclerosis
#16
REVIEW
Udip Dahal, Dikshya Sharma, Kumud Dahal
Association of infection with atherosclerosis is by no means new. Several sero-epidemiological and pathologic studies as well as animal models have shown a link between infection and atherosclerosis. Exciting discoveries in recent times related to role of inter-individual genetic variation in modulating inflammatory response to infection have reignited the enthusiasm in proving a causal link between infection and atherosclerosis. The purpose of this article was to review and analyze the available evidence linking infection with atherosclerosis...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28496557/in-stent-restenosis-due-to-stent-recoil-after-third-generation-drug-eluting-stent-implantation
#17
Yuta Kato, Atsushi Iwata, Masayuki Nakamura, Shin-Ichiro Miura, Keijiro Saku
A 72-year-old man with a heavily calcified coronary lesion underwent percutaneous coronary intervention (PCI) using a third-generation drug-eluting stent (DES) with thin stent struts. Two months after the PCI, in-stent restenosis due to stent recoil (SR) occurred. An intravascular ultrasound (IVUS) revealed deformed stent struts and heavily calcified coronary plaque. The SR probably occurred due to persistent vessel compression as a result of heavily calcified coronary plaque. We should consider using a DES with thick stent struts rather than a third-generation DES with thin stent struts in patients with a heavily calcified coronary lesion...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28496556/epidemiological-profile-of-hispanics-admitted-with-acute-myocardial-infarction-in-puerto-rico-the-experience-of-2007-2009-and-2011
#18
Dagmar F Hernandez-Suarez, Anthony D Osterman-Pla, Onelys Carrasquillo, Juan Aranda, Stella Baez, Mariel Lopez, Enid J Garcia-Rivera
BACKGROUND: A limited number of studies have been published about coronary artery disease in Hispanics, particularly among the Puerto Rican population. The aim of this study was to present a clinical epidemiological profile and management practices in patients hospitalized in Puerto Rico with acute myocardial infarction (AMI). METHODS: This secondary data analysis from the Puerto Rico Cardiovascular Surveillance Study included 6,162 patients at 19 hospitals in Puerto Rico, during years 2007, 2009 and 2011...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28496555/effect-of-acupressure-acupuncture-and-moxibustion-in-women-with-pregnancy-related-anxiety-and-previous-depression-a-preliminary-study
#19
Shunji Suzuki, Chiharu Tobe
BACKGROUND: In this preliminary study, we examined the effect of acupressure, acupuncture and moxibustion (oriental treatments) to prevent of the relapse/deterioration of perinatal depression in women with pregnancy-related anxiety and previous depression. METHODS AND RESULTS: Between 2014 and 2016, there were 48 women with pregnancy-related anxiety and previous depression who had delivery at ≥ 22 weeks' gestation in our institute. Of these, oriental treatments were performed in eight and two women (totally 10, 21%) during pregnancy and postpartum, respectively...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28496554/relationship-between-body-mass-index-and-obesity-awareness-in-school-students
#20
Hassan D Alasmari, Abdullah D Al-Shehri, Tariq A Aljuaid, Bassam A Alzaidi, Khaled A Alswat
BACKGROUND: The primary aim was to assess the prevalence of overweight and obesity among the participants and its relationship to obesity awareness. METHODS: A cross-sectional study that included intermediate and high schools students was conducted between April 2014 and June 2015. Anthropometric measurements were obtained by the researchers and body mass index (BMI) was calculated. We used the obesity risk knowledge (ORK-10) scale to assess obesity awareness. Participants who answered ≥ 5 out of 10 questions correctly were considered to be aware...
June 2017: Journal of Clinical Medicine Research
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