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Journal of Advanced Pharmaceutical Technology & Research

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https://www.readbyqxmd.com/read/30338238/levothyroxine-improves-paraoxonase-pon-1-serum-levels-in-patients-with-primary-hypothyroidism-case-control-study
#1
Marwa S Al-Naimi, Nawar R Hussien, Huda A Rasheed, Hayder M Al-Kuraishy, Ali I Al-Gareeb
Primary hypothyroidism is associated with oxidative stress and insufficient antioxidant capacity. This study was conducted to evaluate the effects of levothyroxine replacement therapy on paraoxonase 1 (PON-1) serum levels in a patients with primary hypothyroidism. Thirty-one patients with primary hypothyroidism compared to 20 healthy controls were recruited from. A venous blood sample were taken after an overnight fasting for biochemical parameters, before and after starting levothyroxine therapy (100 μ g/day) for 3 months duration...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338237/comparison-of-the-effects-of-debriefing-methods-on-psychomotor-skills-self-confidence-and-satisfaction-in-novice-nursing-students-a-quasi-experimental-study
#2
Shahriar Ostovar, Atefeh Allahbakhshian, Leila Gholizadeh, Sima Lak Dizaji, Parvin Sarbakhsh, Akram Ghahramanian
Oral debriefing (OD) and video-assisted debriefing (VAD) are commonly used debriefing methods, with no evidence of superiority of one to another. The present study aimed to compare the effects of OD and VAD on the development of learning outcomes in nursing students. This is a quasi-experimental study. A total of 50 first-year nursing students participated in this study. Participants in the control group participated in OD and those in the intervention group took part in VAD. Debriefing improved psychomotor skills, self-confidence, and student satisfaction in both groups...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338236/a-comparative-study-on-infusion-of-usual-dose-of-oxytocin-and-80-units-dose-of-oxytocin-in-the-prevention-of-postpartum-hemorrhage-in-cesarean-section
#3
Fatemeh Ahmadi
Postpartum hemorrhage is one of the main causes of mothers' death mostly in developing country. The frequency of postpartum hemorrhage after natural pregnancy and cesarean are reported 2%-4% and 6%, respectively. The main goal of this study is to compare two regimens of oxytocine: One with high dose and the other with normal one to prevent uterine atony. The study has been done via a clinical trial method on 150 pregnant women in Zahedan, Iran. The society is randomly divided into two groups. The patients having risk factors of uterine atony and postpartum hemorrhage were omitted from the list...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338235/spiritual-interventions-for-preventing-hiv-aids-in-iran
#4
Zeinab Ghaempanah, Nadereh Memaryan, Mostafa Kochakzaei, Mehrdad Kazemzadeh Atoofi, Abul Fadl Mohsin Ebrahim
Developing health programs based on the beliefs and values of communities has a great impact. Given the priority and importance of AIDS and its transmission through high-risk sexual behaviors, we sought to design a religious/spiritual intervention for preventing AIDS. Relevant statements were extracted from the literature and spiritual/religion documents, and the study questions were reviewed by a modified Delphi consensus panel. The statements were arranged in four areas of recipients, main components, providers, and settings for spiritual interventions...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338234/effects-of-clomiphene-citrate-for-prevention-of-premature-luteinizing-hormone-surge-in-those-undergoing-intrauterine-insemination-outcome-a-randomized-double-blind-placebo-controlled-trial
#5
Afsoon Zarei, Saeed Alborzi, Elham Askary, Mahshid Alborzi, Fatemeh Shahbazi
The objective of the study is to determine the effects of clomiphene citrate (CC) on preventing premature luteinizing hormone (LH) surge in infertile patients with polycystic ovary syndrome (PCOS) undergoing intrauterine insemination (IUI). This was a randomized clinical trial being performed at Shiraz Mother and Child Hospital. We included 162 women with PCOS selected for IUI cycles. Patients were randomly allocated to receive 150 mg/day CC from the 8th of the cycle though the day of human chorionic gonadotropin (hCG) injection ( n = 81) or nothing in the same period ( n = 81)...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338233/differential-effect-of-metformin-and-or-glyburide-on-apelin-serum-levels-in-patients-with-type-2-diabetes-mellitus-concepts-and-clinical-practice
#6
Hayder M Al-Kuraishy, Ali I Al-Gareeb, Huda J Waheed, Thabat J Al-Maiahy
Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant adipocytokine changes which may play an important role in the progression of insulin resistance and micro- and macro-vascular complications. Therefore, the objective of this study was to assess the differential effect of metformin alone or in combination with glyburide on apelin serum levels in patients with T2DM. In this case-control study, fifty patients with T2DM in the age range of 45-65 years and twenty-five healthy controls matched for age and body weight were recruited from single endocrinology center, subdivided according to the diabetic pharmacotherapy into: Group I: healthy controls ( n = 25), Group II: T2DM patients on metformin ( n = 15), Group III: T2DM patients on glyburide ( n = 17), and Group IV: T2DM patients on metformin plus glyburide ( n = 28)...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338232/comparison-of-edema-and-ecchymosis-in-rhinoplasty-candidates-after-lateral-nasal-osteotomy-using-piezosurgery-and-external-osteotomy
#7
Mohammad Ali Ghavimi, Saeed Nezafati, Javad Yazdani, Tannaz Pourlak, Masoumeh Amini, Tala Pourlak, Arezu Ghoreishizadeh, Ramin Negahdari
Rhinoplasty is done with external and endonasal methods. One of the main stages of rhinoplasty in both external and endonasal methods is the lateral nasal osteotomy. Lateral nasal osteotomy is the main cause of edema and ecchymosis after rhinoplasty, which is annoying and unpleasant for patients. Piezosurgery is a new method that uses electronic-ultrasonic waves to perform nasal osteotomies. The aim of this study was to compare of edema and ecchymosis after lateral nasal osteotomy using piezosurgery with external osteotomy in rhinoplasty candidates...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338231/modeling-of-solvent-effects-on-phytocompounds-extraction-from-glycyrrhizae-radix
#8
Nikolay Nikolaevich Boyko, Dmitriy Pisarev, Elena Zhilyakova, Oleg Novikov, Victoria Kuznietsova, Natalia Sushchuk
The aim of the article was to study and model solvent effects on phytocompounds' extraction from Glycyrrhizae radix for substantiation of rational choice of the extractant in the technology of drugs obtained from this type of plant raw material. The process of extraction was carried out by simple maceration for 24 h at temperature 25°C ± 1°C and extractant/plant raw material ratio 5:1 (v/w). The content of hydro-ethanolic extracts based on ethanol solutions with concentration of 22, 41, 50, 71, 82, and 96% ± 1% v/v and some other solvents was studied by reversed phase high-performance liquid chromatography...
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30338230/polymeric-nanocapsules-an-emerging-drug-delivery-system
#9
EDITORIAL
Upendra Nagaich
No abstract text is available yet for this article.
July 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30131939/stability-study-of-azelaic-acid-proethosomes-with-lyoprotectant-as-stabilizer
#10
Hervianti Nurfitria Nugrahani, Iskandarsyah, Harmita
The ethosomal carrier system can increase the penetration of azelaic acid into the stratum corneum, but ethosomes have both physical (particle aggregation or fusion) and chemical instability (chemical interaction of active ingredients during storage) that are often encountered in long-term storage. The aim of this study is to acquire proethosome formula of azelaic acid with lyoprotectant which has better stability than ethosomes of azelaic acid. Azelaic acid proethosomes were measured its absorbance using an ultraviolet-visible is spectrophotometer at a wavelength of 204 nm to obtain a percentage of entrapment efficiency (EE%)...
April 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30131938/epidemiologic-study-of-familial-type-2-diabetes-in-tehran
#11
Mostafa Najafipour, Masoumeh Zareizadeh, Farzad Najafipour
Type 2 diabetes is the most common cause of hyperglycemia. It has different prevalence in various populations. It has been found out that type 2 diabetes is a genetic disorder; however, its inheritance and its type have not been well defined. In studying the genes involved in the development of diabetes, several genes have been introduced as candidates; however, the gene or genes involved in diabetes cannot be identified yet. As family diabetes has not been studied in Iran so far, this study was conducted on a population aged over 20 years in east of Tehran...
April 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30131937/evaluation-of-patient-satisfaction-of-the-status-of-appointment-scheduling-systems-in-outpatient-clinics-identifying-patients-needs
#12
Mohammad Reza Mazaheri Habibi, Fahimeh Mohammad Abadi, Hamed Tabesh, Hasan Vakili-Arki, Ameen Abu-Hanna, Saeid Eslami
Appointment scheduling systems are potentially useful tools for enhancing the patient satisfaction. This study was conducted to inspect patient's needs and satisfaction of the current status of appointment scheduling systems in outpatient clinics. This cross-sectional study was conducted in 10 outpatient clinics with different specializations. The outpatient clinics were selected based on the stratified randomization method. Data were collected using a questionnaire from December 2016 to March 2017. The questionnaire reliability was measured with the participation of 15 patients using the test-retest method...
April 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30131936/comparison-of-balance-and-stabilizing-trainings-on-balance-indices-in-patients-suffering-from-nonspecific-chronic-low-back-pain
#13
Mohammad Hosseinifar, Asghar Akbari, Maher Mahdavi, Maliheh Rahmati
The objective of the current research was to compare the impact of balance and stabilizing trainings on balance indices in patients with nonspecific chronic low back pain. In this randomized, controlled, single-blinded clinical trial, 20 people suffering from nonspecific chronic low back pain were randomly assigned to two groups of balance and stabilizing trainings. Trainings of both groups were performed for 6 weeks and four sessions per week. The overall, lateral, and anterior-posterior stability indices, pain, and disability were measured using Biodex balance system, visual analog scale, and Oswestry scale, before and after treatment, respectively...
April 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/30131935/pharmaceutical-applications-of-liquisolid-technique
#14
EDITORIAL
Upendra Nagaich
No abstract text is available yet for this article.
April 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441323/the-ethanolic-extract-of-ashitaba-stem-angelica-keskei-miq-koidz-as-future-antituberculosis
#15
Sri Agung Fitri Kusuma, Yoppi Iskandar, Mutiara Ayu Dewanti
Considering the easy contagion of tuberculosis (TB) disease spread and the emergence of multidrug-resistant TB, which directly impacts the failure of therapeutic goals and mortality rates increasing, TB disease control remains to be the main concern of continuous health development effort. Therefore, the discovery of new TB drug is needed. This research assessed the new natural anti-TB drug from the ethanolic extract of Angelica keiskei stem obtained from Lombok, Indonesia. The objectives of this study were to evaluate the sensitivity of Mycobacterium tuberculosis (Mtb) H37Rv strain to A...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441322/effect-of-vitamin-e-and-omega-3-fatty-acids-in-type-2-diabetes-mellitus-patients
#16
Ashwitha Shruti Dass, Sarala Narayana, P N Venkatarathnamma
Diabetes mellitus (DM) and its complications have been implicated in hyperglycemia-induced oxidative stress. Antioxidants can improve glycemic control, lipid profile, and cognitive functions. We assessed the effect of Vitamin E and omega 3 fatty acids (OFA) on the above parameters. One hundred patients with type 2 DM receiving metformin 500 mg and glimepiride 1 mg were randomized to receive add-on therapy of Vitamin E 400 mg or OFA once daily for 12 weeks and the third group served as control. Fasting blood sugar (FBS), postprandial blood sugar (PPBS), glycated hemoglobin (HbA1c), body mass index (BMI), waist-hip ratio (WHR), lipid profile, and mini-mental state examination were done at baseline and 12 weeks...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441321/quality-evaluation-of-kaempferia-parviflora-rhizome-with-reference-to-5-7-dimethoxyflavone
#17
Yamon Pitakpawasutthi, Chanida Palanuvej, Nijsiri Ruangrungsi
Kaempferia parviflora Wall. ex Baker is a medicinal plant found in the upper Northeastern regions of Thailand, which belongs to Zingiberaceae family. The present study aims to investigate the standardization parameters, to analyze chemical constituents of volatile oil by gas chromatography-mass spectrometry, and to determine the content of 5,7-dimethoxyflavone in K. parviflora rhizomes by thin-layer chromatography (TLC)-densitometry compared to TLC image analysis. K. parviflora rhizomes from 15 different sources throughout Thailand were investigated for morphological and pharmacognostic parameters...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441320/zika-virus-disease-knowledge-among-the-future-health-care-providers-of-the-united-arab-emirates
#18
Syed Arman Rabbani, Farhan Mustafa, Tasneem Shouqair, Itaf Mohamad, Nada Tahsin
Zika virus (ZIKV) disease has become a major public health concern. Although there are no reported cases of ZIKV disease in the United Arab Emirates (UAE), there is a potential risk of transmission due to large expatriate population and high influx of international travelers. This cross-sectional study was conducted to assess the knowledge of ZIKV disease among the students of a medical and health sciences university in the UAE. Their knowledge of ZIKV disease was assessed using a specially designed, pretested, and validated questionnaire...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441319/the-effect-of-calendula-officinalis-versus-metronidazole-on-bacterial-vaginosis-in-women-a-double-blind-randomized-controlled-trial
#19
Zahra Pazhohideh, Solmaz Mohammadi, Nosrat Bahrami, Faraz Mojab, Parvin Abedi, Elham Maraghi
Bacterial vaginosis (BV) is a common disorder among women of reproductive age. This study aimed to compare the effect of a Calendula officinalis extract-based cream and metronidazole on BV among women of reproductive age. In this study, 80 women of reproductive age with BV were randomly assigned to the C. officinalis ( n = 40) or metronidazole ( n = 40). Diagnosis of BV was confirmed when at least 3 of the 4 Amsel criteria were met (pH >4.5, whitish grey or thin homogeneous discharge, release of a fishy odor on adding 10% KOH, and detection of clue cells on microscopic examination)...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/29441318/the-off-label-use-of-drugs-for-parenteral-nutrition-as-a-solvent-of-substances-slightly-soluble-in-water-in-pharmacological-research
#20
Aleksandr L Urakov, Ilshat G Mustafin, Aleksandr V Samorodov, Felix Kh Kamilov, Ferkat A Khaliullin
Because of the problem to evaluate biological activity in water-soluble substances in all phases of preclinical and clinical studies, the research work enabled to develop the original solvent for poorly soluble compounds based on substances for parenteral nutrition. The main aim is to examine the impact of the original solvent based on substances for parenteral nutrition on biological systems exemplified by the hemostatic system, characterized by sensitivity and variability of the effects in response to any impact, and its comparison with the solvents that are conventional in pharmacological research...
January 2018: Journal of Advanced Pharmaceutical Technology & Research
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