Journal of Pharmacy & Bioallied Sciences

This review study investigates how exercise can enhance cognitive ability and mental wellness. Physical activity has been linked to a number of beneficial effects on cognitive function, including increased memory and executive function in adults, improved academic performance in children and adolescents, and potential advantages for people with cognitive impairments or neurodegenerative diseases. Increased cerebral blood flow, the synthesis of neurotrophic factors, and a decrease in oxidative stress and inflammation are the processes driving these effects...

To assess how oral health education (OHE) techniques using braille affect visually impaired children's awareness of oral health, oral hygiene status and practices, plaque, gingival health, and dental caries status. From 2010 to 2020, a thorough literature search will be conducted for studies in the English language using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, Google Scholar, and Open Grey. Data extraction will be done after two reviewers extensively evaluate the papers for qualifying requirements...

The study aimed to assess the prevalence and cause of endodontic treatment in the first permanent molars of children aged ten in Saudi Arabia. Out of 824 children, 104 had dental caries, with a prevalence rate of 12.62%. The research revealed that the most involved teeth were mandibular left first molar, followed by mandibular right first molar, maxillary left first molar, and maxillary right first molar. Majority of patients had grossly decayed teeth, followed by caries, restorations, and endodontic treatment...

OBJECTIVE: The purpose of this study was to assess how oral and maxillofacial surgeons used various diagnostic tools for oral cancer. MATERIALS AND METHODS: A cross-sectional methodology was used, and a standardized questionnaire was given to oral and maxillofacial surgeons randomly chosen sample. The questionnaire gathered information on demographics and the use of diagnostic tools. Data analysis methods included Chi-square testing and descriptive statistics. RESULTS: The study included 200 oral and maxillofacial surgeons in total...

The demand for accurate, faster, and inexpensive sequencing of deoxyribonucleic acid (DNA) is increasing and is driving the emergence of next-generation sequencing (NGS) technologies. NGS can provide useful insights to help researchers and clinicians to develop the right treatment options. NGS has wide applications in novel fields in biology and medicine. These technologies are of great aid to decode mysteries of life, to improve the quality of crops to detect the pathogens, and also useful in improving life qualities...

Antidepressants have anti-inflammatory effects and boost immunity, and dentists should be aware. This case-control study included only those patients who consented to take part and had a ham-d score of at least 16 and a diagnosis of moderate-to-severe depression. Inclusion criteria included adults, those experiencing moderate to severe depression, taking fluoxetine or venlafaxine, and those with twenty or more teeth. Exclusion criteria included tobacco chewers, smokers, women expecting or nursing, periodontal treatment, antibiotics, anti-inflammatory medication, or vitamin/nutritional supplements...

Fluctuations in androgenic hormonal levels are noticeable through women's menstrual cycle. Changes in estrogen and progesterone have been shown to affect periodontium. Many women report an increase in gingival inflammation and discomfort associated with their menstrual cycle, most commonly before the menstrual period. Approximately 80% of women experience complaints of premenstrual syndrome (PMS) 7 to 10 days before menstruation. Therefore, the present study was carried out to check prevalence of PMS and its oral and periodontal manifestations in patients attending dental hospital...

BACKGROUND: An important aspect of the preparation of the access cavity and biomechanical preparation of the root canal is to safeguard as much of the tooth's framework as possible without affecting access and visibility. OBJECTIVES: To compare the impact of the conservative design of access preparation and traditional design of access preparation in association with TruNatomy endodontic instrumentation and WaveOne Gold endodontic instrumentation on resistance to fracture by the design of a cavity for endodontic access using finite element analysis...

BACKGROUND: Periodontal disease, characterized by inflammation and damage to tooth-supporting structures, poses a prevalent oral health concern. Early detection is crucial for effective management. MATERIALS AND METHODS: This study comprised of 60 patients with varying degrees of periodontal disease. Intraoral images were captured using digital cameras, and AI algorithms were trained to analyze these images for signs of periodontal disease. Clinical diagnoses, conducted by experienced periodontal specialists, were used as the reference standard...

AIM: This study aimed to know the potential of diode light amplification by stimulated emission of radiation (LASER) and desensitizing agents on blocking the dentinal tubules, which may further help in reducing the most common dental problem named dentinal hypersensitivity (DH). MATERIALS AND METHODS: Sixty human permanent bicuspids were selected, and preparation was performed in the cervical region measuring 2.5 mm × 2.5 mm × 2.5 mm, followed by acid etching for 15 seconds...

BACKGROUND: Achieving an optimal shade match for these restorations is crucial for aesthetic outcomes. The thickness of zirconia/glass veneer and the choice of implant abutment material play vital roles in determining the final shade of implant restorations. MATERIALS AND METHODS: This study investigated the influence of zirconia/glass veneer thickness (0.5 mm and 1.0 mm) and implant abutment material (zirconia and titanium) on the final shade of implant restorations...

BACKGROUND: Knowledge and awareness studies reveal the basic information of the community and the misconceptions in relation to practices of a disease. The identification of such factors is important as they directly influence the health care-related interventions. Hypertension is one of the emerging noncommunicable diseases (NCDs) globally. So, we conducted this study to assess the status of our community regarding hypertension. MATERIALS AND METHODS: The study was conducted on 300 hypertensive patients to assess the knowledge and awareness by a hypertension fact questionnaire...

BACKGROUND: In health care industry, incident reporting systems are considered effective instruments to learn from adverse events and errors and improve the quality of health care of all the stake holders. The present study has analyzed the challenges and barriers facing the medical staff to report incidents and events in magnetic resonance imaging (MRI) practices in government hospitals of Saudi Arabia. MATERIALS AND METHODS: A well-structured MRI safety questionnaire was the primary data collection method, utilizing a quantitative descriptive, cross-sectional survey to highlight the challenges and barriers to incidents reporting in MRI practices...

Lichenoid reactions occur exclusively in people who chew tobacco, areca nut, or both, in raw or any manufactured or processed form. The lesion is described as a lichen-planus-like lesion and is termed as quid-induced lichenoid reaction (QILR). In this cross-sectional study, amongst 935 quid consumers, 82 patients were diagnosed with QILR and it was seen that 65 patients used processed forms of tobacco and areca nut. Thereby, it could be concluded that QILR might occur because of flavors used in processing of tobacco and areca nut...

BACKGROUND: The interaction between type 2 diabetes and periodontal disease underscores the importance of exploring dietary interventions that could mitigate inflammation and improve periodontal health in diabetic patients. MATERIALS AND METHODS: This randomized controlled trial included 100 patients with type 2 diabetes who were equally divided into two groups: Group A (low-carbohydrate diet) and Group B (control group). Patients in Group A followed a low-carbohydrate diet for 12 weeks, while Group B maintained their regular dietary habits...

BACKGROUND: This randomized controlled trial aimed to compare the aesthetic outcome and patient perception of immediate versus DL of implant-supported single crowns. METHODS: A total of 60 patients with a single missing tooth were enrolled and randomly assigned to two groups: immediate loading (IL) and delayed loading (DL). Each group consisted of 30 patients with a total of 30 implants. In the IL group, crowns were loaded onto implants immediately after placement, while in the DL group, a healing period of 3 months was observed before crown placement...

OBJECTIVE: Purpose: To evaluate the efficacy of water flossing to traditional flossing in lowering the bleeding on probing (BOP) index around dental implants. METHODS AND MATERIALS: This single-center, examiner-masked research enrolled patients with implants and randomly allocated them to one of two groups. The research analyzed the effectiveness of manual toothbrushes when used with either string floss or a water flosser. RESULTS: After 30 days, the main result was a decrease in BOP occurrence...

AIM: The purpose of this study was to determine how effectively four distinct apex locators could diagnose root perforations in terms of accuracy and repeatability. MATERIALS AND METHODS: Eighty mandibular premolars with a single root were instrumented. The distal face of the root was perforated at both the apical and middle thirds, five millimeters from the apical terminus. K-files connected to apex locators were used for detection on teeth set in an alginate-filled box...

OBJECTIVES: The study's objective is to evaluate the fracture resistance of a tooth that has had endodontic treatment and has been rebuilt using various post and core systems. MATERIALS AND METHODS: Thirty-six extracted premolar teeth of similar sizes were picked, and at random, they were separated into three groups: group A received stainless-steel posts, group B received zirconia fiber posts, and group C received glass fiber posts. Dual-cured resin cement was used to cement each post...

OBJECTIVES: To ascertain whether a link exists between vitamin D insufficiency and early childhood caries or not. METHOD: From the out patient department (OPD) of the Pedodontics Department at Vyas Dental College, a random sample of 40 kids between the ages of 8 months and 5 years old was chosen. Each kid had blood drawn to check their serum 25(OH) vitamin D levels. All of the data was collated and given the necessary statistical analysis. RESULT: The case group's mean serum 25(OH) vitamin D level was 10...