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Journal of Pharmacy & Bioallied Sciences

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https://www.readbyqxmd.com/read/29657508/hypnotic-effect-of-red-cabbage-brassica-oleracea-on-pentobarbital-induced-sleep-in-mice
#1
Azar Hosseini, Mohammad-Ali Sobhanifar, Fatemeh Forouzanfar, Azita Aghaee, Hassan Rakhshandeh
Objective: The present study was performed to investigate the effect of hydroalcoholic extract of red cabbage and its fractions on sleeping behavior in mice. Materials and Methods: The extract and its fractions were injected to mice and sleep duration as well as sleep latency were recorded. Furthermore, toxicity of the extract was determined both in vivo and in vitro . Results: The extract increased sleep duration at doses of 50-200mg/kg ( P < 0...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657507/initial-response-of-human-bone-marrow-derived-stem-cells-after-contact-with-ultrahigh-molecular-weight-polyethylene-uhmwpe-material-an-in-vitro-study-on-cell-viability-and-interleukin-6-expression
#2
Iwan B Anwar, Asep Santoso, Eko Saputra, Rifky Ismail, J Jamari, Emile van der Heide
Introduction: Ultrahigh-molecular-weight polyethylene (UHMWPE) is a thermoplastic polymer useful in biomaterial applications, especially in orthopedic field. Yet, little is known concerning its initial effect on human bone marrow stem cells (hBMSCs) after implantation. Materials and Methods: A cytotoxicity analysis was performed with a 3-(4,5-dimethylthiazol 2-yl)-2,5-diphenyltetrazolium assay after 24, 48, and 72h of incubation of hBMSC culture. Expression of interleukin-6 (IL-6) was measured using enzyme-linked immunosorbent assay...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657506/-in-vivo-evaluation-of-the-anticancer-activity-of-the-gemcitabine-and-doxorubicin-combined-in-a-nanoemulsion
#3
Mayson H Alkhatib, Wafa S Alshehri, Faiza B Abdu
Context: Doxorubicin (DOX) and gemcitabine (GEM) are anticancer drugs that were combined in a nanoemulsion (NE) to reduce their adverse side effects. Aim: To detect the antitumor activity of the combination formulas of GEM and DOX, loaded either in water (GEM+DOX-Sol) or in NEs (GEM-DOX combination/loaded NE [GEM+DOX/LNE]), in female Swiss albino mice inoculated with Ehrlich ascites carcinoma (EAC). Settings and Design: The anticancer assessment of the NE formulas was implemented in 200 mice, which were divided into 10 groups...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657505/knowledge-and-attitude-of-health-care-professionals-toward-adverse-drug-reactions-reporting-at-king-saud-medical-city
#4
Khaja Moinuddin, Sheraz Ali, Amal Qadri Al-Aqqad, Sara Osama Salem, Maram Abdullah Al-Dossari, Abdullah Mohammad Ananzeh, Jaffer Bin Baqar
Background: Health-care professionals across the globe are obligated to report adverse drug reactions (ADRs). The knowledge of ADRs and attitude of health-care professionals toward ADRs reporting is vital for patient safety. This study intends to investigate the knowledge of ADRs and attitude of health-care professionals toward ADRs reporting. Materials and Methods: A cross-sectional study using an anonymous questionnaire was conducted over a period of 3 months (September 2016 to November 2016) at King Saud Medical City, Riyadh, Saudi Arabia...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657504/safety-evaluation-of-various-vector-repellents-in-combination-with-deltamethrin-in-wistar-rats
#5
Anitha Magesh, Senthilkumar Sivanesan, Vijayaraghavan Rajagopalan, Royapuram Veeraragavan Geetha, Anitha Roy
Background: Vector repellents are used globally to avoid insect bites and control transmission of diseases. It is important to ensure safety levels of these compounds, although they are noxious to insects. Vector repellents when used in combination are known to bring additional benefits in getting rid of the harmful insects. Unfortunately, the safety levels of various vector repellents such as Deet ( N , N -diethyl- m -toluamide), Depa ( N , N -diethyl phenylacetamide), and Deb ( N , N -diethylbenzamide) are not studied in combination with the widely used pyrethroid deltamethrin (Del)...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657503/phytochemical-constituents-and-antimicrobial-activity-of-the-ethanol-and-chloroform-crude-leaf-extracts-of-spathiphyllum-cannifolium-dryand-ex-sims-schott
#6
Arunachalam Dhayalan, Daniel E Gracilla, Renato A Dela Peña, Marilyn T Malison, Christian R Pangilinan
Context: The study investigated the medicinal properties of Spathiphyllum cannifolium (Dryand. ex Sims) Schott as a possible source of antimicrobial compounds. Materials and Methods: The phytochemical constituents were screened using qualitative methods and the antibacterial and antifungal activities were determined using agar well diffusion method. Statistical Analysis: One-way analysis of variance and Fisher's least significant difference test were used...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657502/knowledge-attitude-and-practice-regarding-the-risk-of-cardiovascular-diseases-in-patients-attending-outpatient-clinic-in-kuantan-malaysia
#7
Nursyafiza B Mohammad, Nor Azlina A Rahman, Mainul Haque
Background: Cardiovascular disease (CVD) is a leading cause of death around the world including Malaysia. Ischemic heart disease (IHD) is the single largest cause of death in the developed countries and is one of the main contributors to the disease burden in developing countries. Materials and Methods: This was a cross-sectional study conducted to determine knowledge, attitude, and practice (KAP) regarding the risk of CVD in patients attending an outpatient clinic in Kuantan, Malaysia...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29657501/evaluation-of-bloodletting-cupping-therapy-in-the-management-of-hypertension
#8
Moawia M Al-Tabakha, Farah Tariq Sameer, Mai Hafiz Saeed, Rahaf Montaser Batran, Nada Tarek Abouhegazy, Alaa A Farajallah
Background: Bloodletting cupping therapy (Hijama) is a traditional alternative medicine practiced in different cultures. Claims about the therapeutic efficacy of Hijama in hypertension are contradictory. The aim of this project was to determine if Hijama therapy is beneficial in the treatment of patients with hypertension. Materials and Methods: In this retrospective study, 60 files for patients treated for hypertension, aged 40-60 years and whose systolic blood pressure (SBP) is at least 140mm Hg, were used...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284986/management-of-tooth-surface-loss-of-varying-etiology-with-full-mouth-all-ceramic-computer-aided-design-computer-aided-manufacture-restorations
#9
Nirmal Famila Bettie, Saravanan Kandasamy, Venkat Prasad
The anatomical form of a tooth can undergo changes leading to loss of tooth form. The loss of tooth surface can be due to varying etiology. Dental caries, attrition, abrasion, erosion, involving any surface of the tooth can lead to loss of tooth structure. The rate of tooth destruction may proceed to such an extent that the esthetics, function and comfort may be lost. The role of a practioner lies in identification and screening of such case and motivate for oral rehabilitation that includes habit cessation...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284985/a-conservative-method-of-retaining-an-interim-obturator-for-a-total-maxillectomy-patient
#10
Nirmal Famila Bettie
Interim obturators are indicated during the postsurgical phases. It promotes surgical healing and serves as a temporary prosthesis to rehabilitate a patient with intra-oral surgical defect. Retention is gained by wiring, surgical suturing, and other noninvasive methods to enable functional rehabilitation and easy replacement with a permanent obturator. Interim obturators serve as an easy guide for replacing with definitive obturators by indicating prosthesis extensions and the required method of retention. A more conservative and noninvasive method of retaining an interim obturator for a maxillectomy patient is described in this case report...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284984/management-of-tooth-fractures-using-fiber-post-and-fragment-reattachment-report-of-two-cases
#11
Rajesh Gopal, Lalkrishna Raveendran, Sonia P Pathrose, Benin Paulaian
Reattachment of the tooth fragment is an ultraconservative technique for managing coronal tooth fractures when the tooth fragment is available, and there is minimal violation of the biological width. The advances in adhesive dentistry have allowed dentists to use the patient's own fragment to restore the fractured tooth which provides fast and esthetically pleasing results. This article reports fragment reattachment technique and presents two clinical cases of complicated crown fracture.
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284983/biological-rehabilitation-of-complex-oblique-crown-root-fracture-segment-reattachment
#12
Iswarya R Raju, C P Sreedev, Sebeena Mathew, N T Deepa, K Karthick, T Boopathi
Dental trauma can predominantly affect the maxillary anteriors. Trauma can occur to any age group due to accidents, assaults, or leisure activities. The goal of the treatment for traumatically injured teeth is to return the teeth to acceptable function and form. In this case presentation, the endodontic and esthetic treatment approach of crown fracture is presented.
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284982/erosion-infiltration-technique-a-novel-alternative-for-masking-enamel-white-spot-lesion
#13
Praveen Muthuvel, Aarthi Ganapathy, Mohan Kumar Subramaniam, Vanita D Revankar
Enamel White spot lesions are early signs of demineralization under the intact enamel, which may or may not lead to the development of caries. An inactive white spot lesion might act as an arrested dental caries and impair the esthetic appearance by displaying a milky white color from its interior opacity. The first choice of treatment is remineralization with various remineralizing agents such as fluoride and ACP-CCP. Caries infiltration is a less invasive and effective method for arresting the white spot lesions...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284981/neurilemmoma-of-maxillary-alveolus-a-rare-case-report-and-review-of-literature
#14
Saravanan Kandasamy, R Senthil Nathan, Reena Rachel John
Schwannomas or neurilemmomas are benign, slow growing, usually solitary and encapsulated tumor, originating from Schwann cells of the nerve sheath. Intraoral schwannomas account for 1% of head and neck region and are commonly seen at the base of the tongue. Most of the literature, reports of schwannomas in the tongue region are common. In this article we report a rare occurrence of schwannoma in the maxillary alveolus region and its management. A 45 year old female patient reported to the department of oral and maxillofacial surgery with a complaint of swelling in the left maxillary alveolus in relation to molar teeth that had been present for more than 3 months...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284980/esthetic-management-of-compromised-ridge-in-the-anterior-maxilla-a-modified-prosthetic-approach
#15
R Lambodharan, B Sivasaranya, V R Balaji, Divagar Chandrasekaran
Replacing a missing tooth with an implant, especially in the esthetic zone has been increasing demand for the patient. Placing dental implants in the esthetic zone, especially in the compromised ridge with thin gingival thin biotype is considered to be the ultimate challenge for many dentists. This case report illustrates the implant placement in the traumatic anterior maxilla with thin gingival biotype (Class IV) and a modified approach in prosthetic placement.
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284979/evaluation-of-the-accuracy-of-cone-beam-computed-tomography-for-immediate-implant-placement-a-case-report
#16
B Saravanan, P Jayavelu, R Riaz, A R Tariqsalam
Diagnostic imaging acts as a distinctive method in analyzing and drawing in the appropriate treatment protocol for any procedure. Pertaining to immediate implant placement, determining the bone width and height plays a vital role in the success of the implant therapy. This visualization of the measurements done preoperatively will enhance the treatment by reducing the overall time span of the procedure. Currently, cone beam computed tomography (CBCT) plays a significant role in the preoperative determination of the measurements of the tooth and the bone...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284978/successful-surgical-management-of-palatogingival-groove-using-platelet-rich-fibrin-and-guided-tissue-regeneration-a-novel-approach
#17
J V Karunakaran, Susan Mathew Fenn, N Jayaprakash, N Ragavendran
Palatogingival groove also known as radicularlingual groove is a developmental anomaly involving the lingual surface of the maxillary incisors. They are inconspicuous, funnel-shaped, extend for varying distances on root surface and occur due to infolding of the hertwigs epithelial root sheath. This encourages adherence of microorganisms and plaque to levels significant for pathological changes resulting in endodontic and periodontal lesions. The variations in anatomy of the tooth as a cause of pulp necrosis in teeth of anterior maxillary segment should be considered by the clinician when other etiological factors are ruled out...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284977/rehabilitation-of-anterior-maxilla-with-dental-implants-in-periodontally-compromised-patient
#18
D Manikandan, V R Balaji, R Lamobodharan, R Mahalakshmi
Although implant is the treatment of choice for rehabilitation of patients with aggressive periodontitis, it is also challenging for the dentists. There are various views about success of implant therapy for these patients. Few authors have proposed that aggressive periodontitis patients have less success rate of implant survival, while many authors have shown successful management of aggressive periodontitis patients with implants. For implants to be successful in these patient, it is important to control the periodontal disease before placement of implants...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284976/pterygoid-implant-for-atrophic-posterior-maxilla
#19
V R Balaji, R Lambodharan, D Manikandan, S Deenadayalan
Replacement of missing teeth in the posterior maxilla is always a challenge for the treating implant surgeon as the posterior maxilla has several obstacles in the form of quality, quantity, the anatomy of the maxillary sinus, and inaccessibility. To overcome these deficiencies, several surgical procedures such as sinus lift, bone augmentation, tilted implants, short implants, and zygomatic implants were tried. Since these procedures have their own limitations, pterygomaxillary region provides us an excellent place for placement of implant and rehabilitation of posterior maxilla...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284975/dental-implants-a-remote-option-in-case-of-somatic-delusion-disorder
#20
Thanvir Mohamed Niazi, G Ulaganathan, S Kalaiselvan, R Lambodharan, R Mahalakshmi, M Sophia, V Usha Giridhar
A 29-year-old female was referred by a psychiatrist for dental implantation and prosthodontic rehabilitation, as she had all her healthy permanent teeth extracted within a span of 2-6 months, due to somatic delusional disorder. She presently refuses artificial dentures and implants with the fear of having worms in her teeth and the fear not yet allayed. The patient cannot be treated for her edentulous state until her psychiatric symptoms are treated. This is the limitation for the implant surgeon where service rendered is impaired in spite of advanced professional skills, ideal patient ridge, and other factors, just where the patient is not mentally prepared for the dental rehabilitation procedures...
November 2017: Journal of Pharmacy & Bioallied Sciences
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