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Journal of Pharmacy & Bioallied Sciences

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https://www.readbyqxmd.com/read/28979077/developing-an-integrated-treatment-pathway-for-a-post-coronary-artery-bypass-grating-cabg-geriatric-patient-with-comorbid-hypertension-and-type-1-diabetes-mellitus-for-treating-acute-hypoglycemia-and-electrolyte-imbalance
#1
Atta Abbas Naqvi, Amna Shah, Rizwan Ahmad, Niyaz Ahmad
INTRODUCTION: The ailments afflicting the elderly population is a well-defined specialty of medicine. It calls for an immaculately designed health-care plan to treat diseases in geriatrics. For chronic illnesses such as diabetes mellitus (DM), coronary heart disease, and hypertension (HTN), they require proper management throughout the rest of patient's life. An integrated treatment pathway helps in treatment decision-making and improving standards of health care for the patient. CASE PRESENTATION: This case describes an exclusive clinical pharmacist-driven designing of an integrated treatment pathway for a post-coronary artery bypass grafting (CABG) geriatric male patient with DM type I and HTN for the treatment of hypoglycemia and electrolyte imbalance...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979076/development-and-optimization-of-dispersible-tablet-of-bacopa-monnieri-with-improved-functionality-for-memory-enhancement
#2
Vaishali Tejas Thakkar, Amol Deshmukh, Lal Hingorani, Payal Juneja, Lalji Baldaniya, Asha Patel, Tosha Pandya, Mukesh Gohel
INTRODUCTION: The Bacopa monnieri is traditional Ayurvedic medicine, and reported for memory-enhancing effects. The Bacoside is poorly soluble, bitter in taste and responsible for the memory enhancement action. Memory enhancer is commonly prescribed for children or elder people. OBJECTIVE: Poor solubility, patient compliance and bitterness were a major driving force to develop taste masked β-cyclodextrin complex and dispersible tablets. MATERIALS AND METHODS: The inclusion complex of Bacopa monnieri and β-cyclodextrin was prepared in different molar ratios of Bacopa monnieri by Co-precipitation method...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979075/effect-of-the-inclusion-nanocomplex-formed-of-titanium-tetrafluoride-and-%C3%AE-cyclodextrin-on-enamel-remineralization
#3
Thiago Isidro Vieira, Camila Nassur, Adílis Kalina Alexandria, Luciana Pomarico, Valeria Pereira Sousa, Lúcio Mendes Cabral, Ana Maria G Valença, Lucianne Cople Maia
OBJECTIVE: Titanium tetrafluoride (TiF4) is a topical agent used in the control of dental caries; however, it is highly acidic. To minimize this effect, cyclodextrins (CDs) are used. This study evaluated the in vitro potential of TiF4 and β-CD on remineralization. METHODS: Forty bovine enamel blocks were selected by microhardness and randomly assigned to four groups (n = 10 per group): control (distilled and deionized water), 1% β-CD solution, 1% TiF4 solution, and TiF4: β-CD solution...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979074/oral-health-status-and-treatment-needs-of-gunj-marketing-yard-laborers-of-raichur-city-karnataka
#4
B Vengal Rao, A M Suresh Babu, S K Kamalsha, M Sirisha Rao, K Karthik
BACKGROUND: Oral health is a vital part of general health and is a valuable asset of every individual. The working population in India usually belong to the lower socioeconomic group. AIM: This study was conducted to assess the oral health status and treatment needs of Gunj marketing yard laborers. MATERIALS AND METHODS: A descriptive study was conducted among 550 laborers of Gunj marketing yard of Raichur city. A specially designed questionnaire was used to assess the demographic variables and oral hygiene practices...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979073/glycosides-based-standardized-fenugreek-seed-extract-ameliorates-bleomycin-induced-liver-fibrosis-in-rats-via-modulation-of-endogenous-enzymes
#5
Amit D Kandhare, Subhash Laxmanrao Bodhankar, Vishwaraman Mohan, Prasad A Thakurdesai
BACKGROUND: Liver fibrosis a complex process of excess collagen deposition resulted in disturbance of hepatic cellar function. Glycosides based standardized fenugreek seed extract (SFSE-G) has potent anti-inflammatory, antioxidant, and anti-fibrotic properties. OBJECTIVE: The aim of this study is to evaluate the hepatoprotective potential of SFSE-G against bleomycin (BLM)-induced liver fibrosis in laboratory animals. MATERIALS AND METHODS: Sprague-Dawley rats (180-220 g) were assigned to various groups, namely, normal, sham, BLM control, SFSE-G (5, 10, 20, and 40 mg/kg, p...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979072/increased-risk-of-osteoporosis-in-depressive-patients-with-erectile-dysfunction-a-cross-sectional-study-from-malaysia
#6
Abdul Rahman Fata Nahas, Syed Azhar Syed Sulaiman
BACKGROUND: Depression imposes numerous changes on depressive men, promoting for low bone mineral density (BMD) and erectile dysfunction (ED), yet no published data on exploring the possible association between these two disorders among depressive men. We therefore investigated whether low BMD is associated with ED among depressive men and highlighted the possible mutual underlying factors that might give rise to these two disorders in this specific group of patients. MATERIALS AND METHODS: In this cross-sectional study, 119 depressive men were recruited and their sociodemographic and clinical characteristics were obtained...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979071/risk-versus-benefit-who-assesses-this-in-the-management-of-patients-on-ototoxic-drugs
#7
REVIEW
Katijah Khoza-Shangase
The current paper is an attempt at highlighting important strategic indicators, as well as important variables, that the audiology community needs to consider in order to play a more central role in pharmaco-vigilance as part of pharmaco-audiology. Pharmaco-vigilance is an important aspect of pharmacological treatment of disease. In developing countries, where burden of disease is high with resource constraints dictating healthcare priorities; it is important to deliberate on risk/benefit of medications prescribed to treat disease...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979070/%C3%AE-glucosidase-inhibitory-activity-of-selected-malaysian-plants
#8
REVIEW
Dzatil Awanis Mohd Bukhari, Mohammad Jamshed Siddiqui, Siti Hadijah Shamsudin, Md Mukhlesur Rahman, Siti Zaiton Mat So'ad
Diabetes is a common metabolic disease indicated by unusually high plasma glucose level that can lead to major complications such as diabetic neuropathy, retinopathy, and cardiovascular diseases. One of the effective therapeutic managements of the disease is to reduce postprandial hyperglycemia through inhibition of α-glucosidase, a carbohydrate-hydrolyzing enzyme to retard overall glucose absorption. In recent years, a plenty of research works have been conducted looking for novel and effective α-glucosidase inhibitors (AGIs) from natural sources as alternatives for the synthetic AGI due to their unpleasant side effects...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28979069/novel-pathogens-in-periodontal-microbiology
#9
REVIEW
K Vidya Hiranmayi, K Sirisha, M V Ramoji Rao, P Sudhakar
Periodontitis is a polymicrobial disease caused by complex interactions between distinct pathogens in a biofilm resulting in the destruction of periodontal tissues. It seems evident that unknown microorganisms might be involved in onset or progression of periodontitis. For many decades, research in the field of oral microbiology failed to identify certain subgingival microbiota due to technical limitations but, over a period of 12 years using molecular approaches and sequencing techniques, it became feasible to reveal the existence of new periodontal pathogens...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717340/erratum-what-is-the-process-of-obtaining-informed-consent-in-a-clinical-trial-is-it-ever-justifiable-to-include-someone-in-a-clinical-trial-without-prior-informed-consent-from-the-individual
#10
(no author information available yet)
[This corrects the article on p. 262 in vol. 8, PMID: 27413357.].
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717339/pregabalin-and-uremic-pruritus
#11
Khichar Purnaram Shubhakaran
No abstract text is available yet for this article.
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717338/perspectives-about-pandemic-influenza-and-its-prophylactic-measures-among-final-year-pharmacy-students-in-karachi-pakistan
#12
Najia Rahim, Wajiha Iffat, Sadia Shakeel, Muhammad Iyad Naeem, Faiza Qazi, Mehwish Rizvi, Iqbal Nasiri, Lubna Bashir, Faisal Muhammad Khan, Hina Yaseen, Shazia Jamshed
AIMS: In flu pandemics, pharmacy students' knowledge, attitudes, and practices are critical to save patients life. The objective of study was to determine the knowledge of and attitude toward the pandemic influenza among the pharmacy students of Karachi, Pakistan. SETTINGS AND DESIGNS: The cross-sectional study was conducted from September to December 2014 by adopting a prevalidated questionnaire distributed to senior pharmacy students (final year) in seven private and public sector universities of Karachi...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717337/effect-of-surface-modification-on-the-in-vitro-protein-adsorption-and-cell-cytotoxicity-of-vinorelbine-nanoparticles
#13
Nandhakumar Sathyamoorthy, Dhanaraju Dasaratha Magharla, Sundar Devendaran Vankayalu
CONTEXT: Nanocarriers possessing long-circulating abilities could take advantage of the pathophysiology of tumor vasculature to achieve spatial placement. To attain such qualities, the drug carriers should possess suitable physicochemical properties such as size and surface hydrophilicity. AIM: The aim of this study was to prepare poly(ε-caprolactone) nanoparticles (NPs) loaded with vinorelbine bitartrate (VB) and to modify its steric properties using polyethylene glycol and poloxamer...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717336/validation-of-a-stability-indicating-spectrometric-method-for-the-determination-of-sulfacetamide-sodium-in-pure-form-and-ophthalmic-preparations
#14
Sofia Ahmed, Noureen Anwar, Muhammad Ali Sheraz, Iqbal Ahmad
INTRODUCTION: Sulfacetamide sodium is a widely used sulfonamide for ophthalmic infections. OBJECTIVE: A number of analytical methods have been reported for the analysis of sulfacetamide but they lack the ability to determine both the active drug and its major degradation product, sulfanilamide, simultaneously in a sample. MATERIALS AND METHODS: In the present study a simple, rapid and economical stability-indicating UV spectrometric method has been validated for the simultaneous assay of sulfacetamide sodium and sulfanilamide in pure form and in ophthalmic preparations...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717335/evaluation-of-therapeutic-effectiveness-of-prescribed-medications-in-patients-with-type-2-diabetes-mellitus-findings-from-a-tertiary-care-hospital-lahore-pakistan
#15
Bareera Rana, Allah Bukhsh, Tahir Mehmood Khan, Ammar Sarwar, Muhammad Ovais Omer, Shazia Qasim Jamshed
AIM: The present study was aimed to highlight the current prescribing pattern of oral hypoglycemia in type 2 diabetes mellitus and to evaluate the therapeutic effectiveness of these therapeutic categories in achieving target glycemic control. METHODS: This is a prospective, cross-sectional, observational study of 6 months' duration conducted in a tertiary care hospital of Lahore, Pakistan. RESULTS: The current research recruited 145 patients presented in diabetes management center of a tertiary care hospital in Lahore, Pakistan...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717334/osteoporosis-knowledge-among-future-healthcare-practitioners-findings-from-a-malaysian-public-university
#16
Mohamed Hassan Elnaem, Shazia Qasim Jamshed, Ramadan Mohamed Elkalmi, Muhammad Farhan Baharuddin, Muhammad Afif Johari, Nur Ashikin Binti Ab Aziz, Siti Farhanah Binti Ahmad Sabri, Nur Akmal Binti Ismail
BACKGROUND AND OBJECTIVES: Students in relevant health-care academic programs are the future professionals who should play an active role in increasing community awareness regarding chronic diseases such as osteoporosis. This research aimed to evaluate the knowledge of osteoporosis, one of the growing health-care burdens in Malaysia, among students belong to three different health occupations programs in a Malaysian University. METHODS: A cross-sectional study design was conducted to assess the level of knowledge on osteoporosis and to explore the potential association between the study program and osteoporosis-related knowledge among medicine, pharmacy, and allied health sciences students in a Malaysian University...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717333/analysis-of-chemical-signatures-of-alkaliphiles-using-fatty-acid-methyl-ester-analysis
#17
Basha Sreenivasulu, Chinthala Paramageetham, Dasari Sreenivasulu, Bukke Suman, Katike Umamahesh, Gundala Prasada Babu
BACKGROUND: Fatty acids occur in nearly all living organisms as the important predominant constituents of lipids. While all fatty acids have essentially the same chemical nature, they are an extremely diverse group of compounds. MATERIALS AND METHODS: To test the hypothesis, fatty acids of alkaliphiles isolates, Bacillus subtilis SVUNM4, Bacillus licheniformis SVUNM8, Bacillus methylotrohicus SVUNM9, and Paenibacillus dendritiformis SVUNM11, were characterized compared using gas chromatography-mass spectrometry (GC-MS) analysis...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717332/homology-modeling-of-leishmania-donovani-enolase-and-its-molecular-interaction-with-novel-inhibitors
#18
Jay Prakash Mahato, Sindhuprava Rana, Maneesh Kumar, Surendra Sarsaiya
INTRODUCTION: The treatment of Indian tropical disease such as kala-azar is likely to be troublesome to the clinicians as AmpB- and miltefosine-resistant Leishmania donovani has been reported. The rationale behind designed a novel inhibitors of model of L. donovani enolase and performing a binding study with its inhibitors to gain details of the interaction between protein residues and ligand molecules. METHODS AND MATERIALS: The L. donovani enolase model consists of two typical domains...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717331/knowledge-and-awareness-of-first-aid-of-avulsed-tooth-among-physicians-and-nurses-of-hospital-emergency-department
#19
Sudeep Sreepad Iyer, Antarmayee Panigrahi, Shalini Sharma
INTRODUCTION: Physicians and nurses of emergency department are often the first line of qualified health-care providers attending the patient in person or parent's query over phone reporting immediately following the dental avulsion. Prompt action by them becomes the decisive factor in survival and prognosis of the tooth. Although a few researchers have evaluated knowledge of emergency room physicians, there is scanty of reports concerning nurses who play a climacteric role. MATERIALS AND METHODS: A 10-item questionnaire regarding clinical situation apropos dental injury and tooth avulsion, inquiring knowledge of physicians and nurses was administered to 150 each of nursing professionals and physicians of the emergency department...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717330/an-experimental-evaluation-of-adaptogenic-potential-of-standardized-epipremnum-aureum-leaf-extract
#20
Sreemoy Kanti Das, Pinaki Sengupta, Mohd Shahimi Mustapha, Md Moklesur Rahman Sarker
BACKGROUND: Stress is a normal part of everyday life but chronic stress can lead to a variety of stress-related illnesses including hypertension, anxiety, and depression. In the present investigation, standardized leaf extract of Epipremnumaureum was evaluated for its anti-stress potential. MATERIALS AND METHODS: For the evaluation of anti-stress activity, groups of mice (n = 6) were subjected to forced swim stress and anoxic stress tolerance test in mice 1h after daily treatment of E...
April 2017: Journal of Pharmacy & Bioallied Sciences
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