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Journal of Pharmacy & Bioallied Sciences

Wan Zanariah W A Manan, Fong Chui Wei, Firdaus Abd Rahman, Long Chiau Ming
No abstract text is available yet for this article.
July 2016: Journal of Pharmacy & Bioallied Sciences
Akosua Adom Agyeman, Richard Ofori-Asenso
No abstract text is available yet for this article.
July 2016: Journal of Pharmacy & Bioallied Sciences
Kennedy Kwami Edem Kukuia, Elvis Ofori Ameyaw, Eric Woode, Priscilla Kolibea Mante, Donatus Wewura Adongo
CONTEXT: Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. AIMS: This study investigated the anticonvulsant properties and possible mechanism of action of the 70% v/v hydroalcoholic extract of the leaves of M. oppositifolius. MATERIALS AND METHODS: Inprinting control region (ICR) mice (25-30 g) were pretreated with the M. oppositifolius leaf extract (10-100 mg/kg) before administering the respective convulsants (pentylenetetrazole [PTZ], picrotoxin [PTX], strychnine [STR], 4-aminopyridine [4-AP], and pilocarpine)...
July 2016: Journal of Pharmacy & Bioallied Sciences
Pooja M Vachhani, Manish N Solanki, Mira K Desai
OBJECTIVES: Evaluation and comparison of ethical standards of published drug promotional literatures (DPLs) between different Indian and non-Indian scientific medical journals regarding compliance to the World Health Organization (WHO) and International Federation of Pharmaceutical Manufacturers and Associations (IFPMAs) guidelines. MATERIALS AND METHODS: A cross-sectional, observational study was carried out at pharmacology department. DPLs published in Indian and non-Indian scientific medical journals available at central library of medical college during the period of 6 months were collected according to selection criteria...
July 2016: Journal of Pharmacy & Bioallied Sciences
Ramadan Mohamed Elkalmi, Akshaya Srikanth Bhagavathul, Adamu Ya'u, Sami Abdo Radman Al-Dubai, Tarek M Elsayed, Akram Ahmad, Wael Mohamed
OBJECTIVES: The objectives of this study were to assess the general public views and familiarity toward electronic cigarette (e-cigarette) in Kuantan, Malaysia. METHODOLOGY: A total of 277 Kuantan people were involved in this study. The questionnaire was distributed at random in shops, businesses, and public places in Kuantan. Statistical analysis was performed using SPSS (version 17.0). RESULTS: From 400 participants, a total number of 277 (160, 57...
July 2016: Journal of Pharmacy & Bioallied Sciences
Rajiv Kumar Gupta, Sunil Kumar Raina, Aruna Kumari Verma, Tejali Shora
CONTEXT: Emergency contraception (EC) is use of drug or device to prevent pregnancy after unprotected sexual intercourse. Unlike other regular methods of contraception which are taken prior to the sexual act, EC is used after the unprotected sex. AIM: To assess the knowledge and attitude toward use of emergency contraceptives among medical students. SETTING AND DESIGN: A cross-sectional questionnaire based study was conducted among all the medical students in the Government Medical College in North-West India...
July 2016: Journal of Pharmacy & Bioallied Sciences
Ain Ayob, Ammar Ihsan Awadh, Juliana Jafri, Shazia Jamshed, Hawa Mas Azmar Ahmad, Hazrina Hadi
BACKGROUNDS: Variety of cosmetic products was used in our daily life, yet the amount and types of the cosmetic products used by the consumers were varied, which may be due to the different perspectives held by each of the consumers. OBJECTIVES: To explore consumers' perspectives toward cosmetic products. METHODS: An interview guide was developed with a set of 12 semistructured questions. Participants in Kuantan, Pahang were recruited via the purposive sampling, and they undergo in-depth face-to-face interviews...
July 2016: Journal of Pharmacy & Bioallied Sciences
Sushrut Varun Satpathy, Supratim Datta, Binu Upreti
OBJECTIVE: Diabetes has gradually emerged as one of the most serious public health problems in our country. This underlines the need for timely disease detection and decisive therapeutic intervention. This prospective cross-sectional observational study aims at analyzing the utilization pattern of antidiabetic agents in a remote North-East Indian tertiary care teaching hospital in the perspective of current standard treatment guidelines. MATERIALS AND METHODS: Diabetic patients receiving antidiabetic medication, both as outpatients and inpatients in our hospital over a period of 12 months (May 2013-May 2014), were included in this study...
July 2016: Journal of Pharmacy & Bioallied Sciences
Shazia Qasim Jamshed, Pei Se Wong, Heng Chin Yi, Gan Siaw Yun, Muhammad Umair Khan, Akram Ahmad
BACKGROUND: World Health Organization has defined self-medication as the selection and use of medications (including herbal and traditional product) by individuals to treat self-recognized illnesses or symptoms. The prevalence of self-medication is reported to be higher among female students. OBJECTIVE: To investigate the awareness and self-medication practices among female students of higher education institutions in Malaysia. METHOD: A descriptive, cross-sectional study was conducted in four higher education institutes of Selangor, Malaysia...
July 2016: Journal of Pharmacy & Bioallied Sciences
Mainak Chakraborty, Indrajit Karmakar, Sagnik Haldar, Avratanu Das, Asis Bala, Pallab Kanti Haldar
INTRODUCTION: The present study evaluates the antioxidant effect of methanol extract of Hippophae salicifolia (MEHS) bark with special emphasis on its role on oxidative DNA damage in mouse peritoneal macrophages. MATERIAL AND METHODS: In vitro antioxidant activity was estimated by standard antioxidant assays whereas the antioxidant activity concluded the H(+) donating capacity. Mouse erythrocytes' hemolysis and peritoneal macrophages' DNA damage were determined spectrophotometrically...
July 2016: Journal of Pharmacy & Bioallied Sciences
Ain Ayob, Ammar Ihsan Awadh, Hazrina Hadi, Juliana Jaffri, Shazia Jamshed, Hawa Mas Azmar Ahmad
BACKGROUND: Increased usage of cosmetic products has caused a growing concern about the safety of these products, and yet little is known about cosmetics from the consumers' perspective. Hence, this study's aim is to develop a valid and reliable tool for assessing consumers' awareness, perceptions, and attitudes toward cosmetic products. MATERIALS AND METHODS: A questionnaire was developed in the English language based on information collected from a literature search, in-depth interviews conducted with consumers prior to this study and consultations with experts...
July 2016: Journal of Pharmacy & Bioallied Sciences
Ibrahim Suliman Al-Aboudi, Mohammed Azmi Hassali, Asrul Akmal Shafie
OBJECTIVE: The purpose of this study was to investigate the association between knowledge and attitude with health-related quality of life (HRQoL) among patients with type 2 diabetes mellitus in Riyadh, Saudi Arabia. MATERIALS AND METHODS: A cross-sectional descriptive study was undertaken with a cohort of 75 patients attending the University Diabetic Center at King Abdulaziz University Hospital, Riyadh, Saudi Arabia. The EuroQoL-five-dimensional (EQ-5D) scale was used to assess HRQoL...
July 2016: Journal of Pharmacy & Bioallied Sciences
Jagbir Singh, Mahesh Kumar, Rani Mansuri, Ganesh Chandra Sahoo, Aakash Deep
AIM: Aim of this work was to design and identify some S-adenosyl-L-homocysteine (SAH) analogs as inhibitors of S-adenosyl-L-methionine-dependent methyltransferase (MTase) protein using computational approaches. INTRODUCTION: According to the current scenario the dengue has been a global burden. The people are being killed by dengue virus in an abundant number. Despite of lot of research being going on dengue worldwide, there is no single drug which can kill its virus...
July 2016: Journal of Pharmacy & Bioallied Sciences
Rajasekhar Komarla Kumarachari, Sivakumar Peta, Abdrrahman Shemsu Surur, Yenus Tadesse Mekonnen
INTRODUCTION: As pyrimidine is a basic nucleus in DNA and RNA, it has been found to be associated with diverse biological activities. Pyrimidine derivatives were reported to possess anticonvulsant, antimicrobial, anti-inflammatory, antitumor, and antihistaminic. Recently, our team reported the anti-inflammatory and antimicrobial evaluation of some pyrimidines. OBJECTIVE: To synthesize, predict and evaluate biological activity of some 2-(N,N-dimethyl guanidinyl)-4,6-diaryl pyrimidines...
July 2016: Journal of Pharmacy & Bioallied Sciences
Zaswiza Mohamad Noor, Alesha J Smith, Simon S Smith, Lisa M Nissen
INTRODUCTION: Community pharmacists are in a suitable position to give advice and provide appropriate services related to sleep disorders to individuals who are unable to easily access sleep clinics. An intervention with proper objective measure can be used by the pharmacist to assist in consultation. OBJECTIVES: The study objectives are to evaluate: (1) The effectiveness of a community pharmacy-based intervention in managing sleep disorders and (2) the role of actigraph as an objective measure to monitor and follow-up individuals with sleeping disorders...
July 2016: Journal of Pharmacy & Bioallied Sciences
Vagish Kumar Laxman Shanbhag
No abstract text is available yet for this article.
April 2016: Journal of Pharmacy & Bioallied Sciences
Vagish Kumar Laxman Shanbhag
No abstract text is available yet for this article.
April 2016: Journal of Pharmacy & Bioallied Sciences
Dinesh M Bramhane, Preethi A Kulkarni, Elvis A F Martis, Raghuvir R S Pissurlenkar, Evans C Coutinho, Mangal S Nagarsenker
AIMS: The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous solubility and consequent translation in in vivo performance of Pioglitazone (PE). MATERIAL AND METHODS: Three cyclodextrins: β-cyclodextrin (BCD), hydroxypropyl-β-cyclodextrin (HPBCD) and Sulfobutylether-7-β-cyclodextrin (SBEBCD) were employed in preparation of 1:1 Pioglitazone complexes by three methods viz...
April 2016: Journal of Pharmacy & Bioallied Sciences
Ahmed Nawaz Khan, Roop Krishen Khar, P V Ajayakumar
OBJECTIVE: The aim of present study was to establish near infrared-chemometric methods that could be effectively used for quality profiling through identification and quantification of amoxicillin (AMOX) in formulated capsule which were similar to commercial products. In order to evaluate a large number of market products easily and quickly, these methods were modeled. MATERIALS AND METHODS: Thermo Scientific Antaris II near infrared analyzer with TQ Analyst Chemometric Software were used for the development and validation of the identification and quantification models...
April 2016: Journal of Pharmacy & Bioallied Sciences
Omar Thanoon Dawood, Mohammed Abd Ahmed Rashan, Mohamed Azmi Hassali, Fahad Saleem
BACKGROUND: Smoking is a major public health problem, especially in Iraq. There is very little information had been documented regarding smoking risk factors and quit intention among Iraqi smokers. OBJECTIVES: The main objectives of this study are to determine smokers' knowledge and perception about smoking health risks; and to determine smoking behavior and quitting intentions among Iraqi smokers; as well as to predict the factors that may associate with quit intentions...
April 2016: Journal of Pharmacy & Bioallied Sciences
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