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World Journal of Cardiology

Alberto Fuensalida, Maurice Cortés, Luigi Gabrielli, Manuel Méndez, Alejandro Martínez, Gonzalo Martínez
We report three cases of Takotsubo syndrome (TS) with atypical myocardial involvement. All three cases were triggered by physical or mental stress, resulting in transient myocardial compromise. However, the clinical presentation, localization and extent of myocardial damage varied in each case, ranging from low-risk acute chest pain to cardiogenic shock with low ejection fraction and dynamic obstruction of the left ventricular outflow tract. These cases outline the range of possible presentations of this rare entity and illustrate atypical forms of TS...
October 26, 2018: World Journal of Cardiology
Alexander N Kharlamov
AIM: To statistically examine the released clinical trials and meta-analyses of polymeric bioresorbable scaffolds resuming the main accomplishments in the field with a translation to the routine clinical practice. METHODS: The statistical power in clinical trials such as ABSORB Japan, ABSORB China, EVERBIO II, AIDA, and few meta-analyses by the post hoc odds ratio-based sample size calculation, and the patterns of artery remodeling published in papers from ABSORB A and B trials were evaluated...
October 26, 2018: World Journal of Cardiology
Salah Am Said, Aly Agool, Arno Hm Moons, Mounir Wz Basalus, Nils Rl Wagenaar, Rogier Lg Nijhuis, Jutta M Schroeder-Tanka, Riemer Hja Slart
AIM: To assess the functionality of congenital coronary artery fistulas (CAFs) using adenosine stress 13 N-ammonia positron emission tomography computed tomography (PET-CT). METHODS: Congenital CAFs were incidentally detected during coronary angiography (CAG) procedures in 11 adult patients (six males and five females) with a mean age of 64.3 years (range 41-81). Patients were collected from three institutes in the Netherlands. The characteristics of the fistulas (origin, pathway and termination), multiplicity of the origins and pathways of the fistulous vessels were assessed by CAG...
October 26, 2018: World Journal of Cardiology
Sorin Giusca, Dorothea Raupp, Dirk Dreyer, Christoph Eisenbach, Grigorios Korosoglou
AIM: To examine the efficacy and safety of the 6 French (6F) Rotarex® S catheter system in patients with acute limb ischemia (ALI) involving thromboembolic occlusion of the proximal and mid-crural vessels. METHODS: The files of patients in our department with ALI between 2015 and 2017 were examined. In seven patients, the Rotarex® S catheter was used in the proximal segment of the crural arteries. Data related to the clinical examination, Doppler sonography, angiography and follow-up from these patients were further used for analysis...
October 26, 2018: World Journal of Cardiology
Salah Eldien Altarabsheh, Salil V Deo, Abeer Rababa'h, Yagthan M Obeidat, Osama Haddad
Chronic ischemic mitral valve regurgitation is a result of disturbed left ventricular geometry secondary to myocardial ischemia in the absence of intrinsic mitral valve pathology. It is a common complication after myocardial infarction, and patients who have ischemic mitral regurgitation (IMR) have a worse prognosis compared to patients who have ischemic heart disease alone, and this is directly related to the severity of IMR. Medical therapy has limited efficacy, and surgical options including various repair techniques and valve replacement had been tried with variable success...
October 26, 2018: World Journal of Cardiology
Stylianos Kastellanos, Konstantinos Aznaouridis, Charalambos Vlachopoulos, Eleftherios Tsiamis, Evangelos Oikonomou, Dimitris Tousoulis
Coronary artery anomalies and variants are relatively uncommon congenital disorders of the coronary artery anatomy and constitute the second most common cause of sudden cardiac death in young competitive athletes. The rapid advancement of imaging techniques, including computed tomography, magnetic resonance imaging, intravascular ultrasound and optical coherence tomography, have provided us with a wealth of new information on the subject. Anomalous origin of a coronary artery from the contralateral sinus is the anomaly most frequently associated with sudden cardiac death, in particular if the anomalous coronary artery has a course between the aorta and the pulmonary artery...
October 26, 2018: World Journal of Cardiology
Luca Liberale, Aldo Bonaventura, Fabrizio Montecucco
Immune system activation and dysfunction characterize the early phase of reperfusion after a myocardial infarction (MI). Despite initially neglected, adaptive immunity has been recently showed to play an important role in this setting. In fact, the immune system can recognize sequestered antigens released by the necrotic tissue, initiating a deleterious autoimmune vicious circle leading to worse outcome. In their recent work, Angelini et al shed the light on a new feature of post-MI which involves two "old players" of post-ischemic myocardial injury: CD31 and matrix metalloproteinase (MMP)-9...
October 26, 2018: World Journal of Cardiology
Ahmed Mashhour, Konstantin Zhigalov, Marcin Szczechowicz, Sabreen Mkalaluh, Jerry Easo, Harald Eichstaedt, Dmitry Borodin, Jürgen Ennker, Alexander Weymann
We present a modified implantation technique of the Perceval® sutureless aortic valve (LivaNova, London, United Kingdom) that involves the usage of snuggers for the guiding sutures during valve deployment. Both limbs of each guiding suture are pulled through an elastic tube, which is fixed with a Pean clamp, which tightens the sutures and fixes the prosthesis to the aortic annulus during valve deployment. This method proved safe and useful in over 120 cases. Valve implantation was facilitated and the need for manipulation by the assistant or the nurse was eliminated...
September 26, 2018: World Journal of Cardiology
Peter Hunold, Heinz Jakob, Raimund Erbel, Jörg Barkhausen, Christina Heilmaier
AIM: To compare myocardial viability assessment accuracy of cardiac magnetic resonance imaging (CMR) compared to [18 F]-fluorodeoxyglucose (FDG)- positron emission tomography (PET) depending on left ventricular (LV) function. METHODS: One-hundred-five patients with known obstructive coronary artery disease (CAD) and anticipated coronary revascularization were included in the study and examined by CMR on a 1.5T scanner. The CMR protocol consisted of cine-sequences for function analysis and late gadolinium enhancement (LGE) imaging for viability assessment in 8 mm long and contiguous short axis slices...
September 26, 2018: World Journal of Cardiology
Kanimozhi Vairamani, Vikram Prasad, Yigang Wang, Wei Huang, Yinhua Chen, Mario Medvedovic, John N Lorenz, Gary E Shull
AIM: To investigate the hypothesis that cardiomyocyte-specific loss of the electrogenic NBCe1 Na+ -HCO3 - cotransporter is cardioprotective during in vivo ischemia-reperfusion (IR) injury. METHODS: An NBCe1 ( Slc4a4 gene) conditional knockout mouse (KO) model was prepared by gene targeting. Cardiovascular performance of wildtype (WT) and cardiac-specific NBCe1 KO mice was analyzed by intraventricular pressure measurements, and changes in cardiac gene expression were determined by RNA Seq analysis...
September 26, 2018: World Journal of Cardiology
Vinasha Ramasamy, Bongani M Mayosi, Edward D Sturrock, Mpiko Ntsekhe
This review article aims to: (1) discern from the literature the immune and inflammatory processes occurring in the pericardium following injury; and (2) to delve into the molecular mechanisms which may play a role in the progression to constrictive pericarditis. Pericarditis arises as a result of a wide spectrum of pathologies of both infectious and non-infectious aetiology, which lead to various degrees of fibrogenesis. Current understanding of the sequence of molecular events leading to pathological manifestations of constrictive pericarditis is poor...
September 26, 2018: World Journal of Cardiology
Jaime González-Montero, Roberto Brito, Abraham Ij Gajardo, Ramón Rodrigo
Acute myocardial infarction (AMI) is the leading cause of death worldwide. Its associated mortality, morbidity and complications have significantly decreased with the development of interventional cardiology and percutaneous coronary angioplasty (PCA) treatment, which quickly and effectively restore the blood flow to the area previously subjected to ischemia. Paradoxically, the restoration of blood flow to the ischemic zone leads to a massive production of reactive oxygen species (ROS) which generate rapid and severe damage to biomolecules, generating a phenomenon called myocardial reperfusion injury (MRI)...
September 26, 2018: World Journal of Cardiology
Nidhish Tiwari, Kavisha Patel
Increasing life expectancy is expected to lead to a corresponding increase in the prevalence of aortic valve disease (AVD). Further, the number of indications for transcatheter aortic valve replacement (TAVR) as a treatment option for AVD is expanding, with a growing role for echocardiography in its management. In this review we summarize the current literature on some newer echocardiographic modalities and the parameters they generate, with a particular focus on their prognostic and clinical value beyond conventional methods in the management of aortic stenosis, TAVR, and aortic regurgitation...
August 26, 2018: World Journal of Cardiology
Mohamed A Effat, Srikara Viswanath Peelukhana, Rupak K Banerjee
[This corrects the article on p. 283 in vol. 8, PMID: 27022460.].
July 26, 2018: World Journal of Cardiology
Michael Spartalis, Eleftherios Spartalis, Eleni Tzatzaki, Diamantis I Tsilimigras, Demetrios Moris, Christos Kontogiannis, Efthimios Livanis, Dimitrios C Iliopoulos, Vassilis Voudris, George N Theodorakis
Ventricular tachycardia (VT) is a crucial cause of sudden cardiac death (SCD) and a primary cause of mortality and morbidity in patients with structural cardiac disease. VT includes clinical disorders varying from benign to life-threatening. Most life-threatening episodes are correlated with coronary artery disease, but the risk of SCD varies in certain populations, with various underlying heart conditions, specific family history, and genetic variants. The targets of VT management are symptom alleviation, improved quality of life, reduced implantable cardioverter defibrillator shocks, prevention of reduction of left ventricular function, reduced risk of SCD, and improved overall survival...
July 26, 2018: World Journal of Cardiology
Konstantinos S Mylonas, Pouya Hemmati, Diamantis I Tsilimigras, Pavlos Texakalidis, Konstantinos P Economopoulos
Data from the last 50 years suggest that pediatric patients typically suffer cardiothoracic injuries following blunt traumatic force (70%) in the setting of either motor vehicle crashes (53.5%) or vehicle-pedestrian accidents (18.2%). Penetrating trauma accounts for 30% of pediatric cardiothoracic injuries, half of which are gunshot wounds. Graduated driver licensing programs, gun-control legislation, off-road vehicle regulation, initiatives such as "Prevent the Bleed", as well as professional society recommendations are key in preventing pediatric cardiothoracic injuries...
July 26, 2018: World Journal of Cardiology
Mahesh Anantha-Narayanan, Dixitha Anugula, Gladwin Das
AIM: To investigate if patent foramen ovale (PFO) closure device reduces the risk of recurrent stroke in patients with cryptogenic stroke. METHODS: We searched five databases - PubMed, EMBASE, Cochrane, CINAHL and Web-of-Science and from January 2000 to September 2017 for randomized trials comparing PFO closure to medical therapy in cryptogenic stroke. Heterogeneity was determined using Cochrane's Q statistics. Random effects model was used. RESULTS: Five randomized controlled trials with 3440 patients were included in the analysis...
June 26, 2018: World Journal of Cardiology
Meridith Ginesi, Michael S Firstenberg
Over the years there has been substantial advanced in the diagnosis and surgical management of complex thoracic aortic disease and complex endocarditis. As these therapies are being offered to a growing segment of patients-and more and more patients are felt to potentially benefit from such therapies, the long-term consequences of these interventions is sometimes poorly understood. While traditional medical complications, such as stroke, renal failure, respiratory failure, and even death are often the focus of outcomes studies, little is known on the impact of these diseases and therapies on mental health...
June 26, 2018: World Journal of Cardiology
Andreas Schuster, Sören J Backhaus, Thomas Stiermaier, Ingo Eitel
Cardiovascular magnetic resonance (CMR) represents the reference standard for cardiac morphology and function assessment. Since introduction in 2009, CMR feature tracking (CMR-FT) has become a frequently used tool in the assessment of myocardial deformation and wall motion on the basis of routinely acquired b-SSFP cine images. Extensive validation has led to excellent intra- and inter-observer as well as inter-study reproducibility. CMR-FT derived myocardial deformation indices such as left ventricular (LV) strain have been shown to be impaired in cardiac diseases such as cardiomyopathies as well as myocardial infarction...
May 26, 2018: World Journal of Cardiology
Maxime Caru, Laurence Kern, Marc Bousquet, Daniel Curnier
AIM: To quantify the preventive fraction of physical fitness on the risk factors in patients with cardiovascular diseases (CVDs). METHODS: A total of 249 subjects (205 men and 44 women) suffering from CVD were categorized into four groups, according to their percentage of physical fitness. We calculated the odds ratio to obtain the preventive fraction in order to evaluate the impact of the physical fitness level on the risk factors ( i.e ., abdominal obesity, depression, diabetes, dyslipidemia, hypertension, obesity, overweight and smoking)...
April 26, 2018: World Journal of Cardiology
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