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International Neurourology Journal

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https://www.readbyqxmd.com/read/28954468/the-authors-reply-reply-on-evidence-is-enough-a-systematic-review-and-network-meta-analysis-of-the-efficacy-of-tamsulosin-0-2-mg-and-tamsulosin-0-4-mg-as-an-initial-therapeutic-dose-in-asian-benign-prostatic-hyperplasia-patients
#1
Su Jin Kim, In-Soo Shin, Sung-Jong Eun, Taeg-Keun Whangbo, Jin Wook Kim, Young Sam Cho, Joon Chul Kim
No abstract text is available yet for this article.
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954467/afferent-pathway-mediated-effect-of-%C3%AE-1-adrenergic-antagonist-tamsulosin-on-the-neurogenic-bladder-after-spinal-cord-injury
#2
Jin-Hee Han, Sung-Eun Kim, Il-Gyu Ko, Jayoung Kim, Khae Hawn Kim
PURPOSE: The functions of the lower urinary tract (LUT), such as voiding and storing urine, are dependent on complex central neural networks located in the brain, spinal cord, and peripheral ganglia. Thus, the functions of the LUT are susceptible to various neurologic disorders including spinal cord injury (SCI). SCI at the cervical or thoracic levels disrupts voluntary control of voiding and the normal reflex pathways coordinating bladder and sphincter functions. In this context, it is noteworthy that α1-adrenoceptor blockers have been reported to relieve voiding symptoms and storage symptoms in elderly men with benign prostatic hyperplasia (BPH)...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954466/letter-to-the-editor-commentary-on-evidence-is-enough-a-systematic-review-and-network-meta-analysis-of-the-efficacy-of-tamsulosin-0-2-mg-and-tamsulosin-0-4-mg-as-an-initial-therapeutic-dose-in-asian-benign-prostatic-hyperplasia-patients
#3
https://www.readbyqxmd.com/read/28954465/particulate-matter-fine-particle-and-urologic-diseases
#4
REVIEW
Eun-A Kim
Particulate matter (PM) has been found to damage vital body organs, including the lungs and heart, through vascular damage and oxidative stress. Recently, renal function and chronic urologic diseases have also been found to be related to PM. To investigate this, we reviewed the characteristics of PM related to renal toxicity, including recent studies on the associations of urologic diseases with PM. PM can include constituents that cause renal toxicity, such as lead, cadmium, arsenic, and crystalline silica, which result in renal tubular or interstitial damage...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954464/meta-analysis-of-the-efficacy-and-safety-of-mirabegron-add-on-therapy-to-solifenacin-for-overactive-bladder
#5
Yankai Xu, Ruihua Liu, Chu Liu, Yuanshan Cui, Zhenli Gao
PURPOSE: We performed a meta-analysis to evaluate the efficacy and safety of mirabegron add-on therapy to solifenacin for patients with overactive bladder (OAB). METHODS: We conducted a systematic literature review to identify all randomized, double-blind, controlled trials (RCTs) of this combination (mirabegron and solifenacin) for OAB. Embase, MEDLINE, and the Cochrane Central Register of Controlled Trials were searched. A manual search was also performed to investigate relevant references from the retrieved studies...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954463/comparison-of-5-different-rat-models-to-establish-a-standard-animal-model-for-research-into-interstitial-cystitis
#6
Phil Hyun Song, So Young Chun, Jae-Wook Chung, Yeon Yong Kim, Hyo Jung Lee, Jun Nyung Lee, Yun-Sok Ha, Eun Sang Yoo, Tae Gyun Kwon, Jeongshik Kim, Dae Hwan Kim, Bum Soo Kim
PURPOSE: We evaluated 5 different rat models using different agents in order to establish a standard animal model for interstitial cystitis (IC) in terms of the functional and pathologic characteristics of the bladder. METHODS: Five IC models were generated in 8-week-old female Sprague-Dawley rats via transurethral instillation of 0.1M hydrogen chloride (HCl) or 3% acetic acid (AA), intraperitoneal injection of cyclophosphamide (CYP) or lipopolysaccharide (LPS), or subcutaneous injection of uroplakin II (UPK2)...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954462/is-there-any-difference-between-depression-and-anxiety-in-overactive-bladder-according-to-sex-a-systematic-review-and-meta-analysis
#7
Iane Glauce R Melotti, Cássia Raquel Teatin Juliato, Suelene Costa de Albuquerque Coelho, Marcelo Lima, Cassio Luiz Zanettini Riccetto
PURPOSE: Overactive bladder (OAB) is characterized by urinary urgency with or without urge incontinence, accompanied by frequency and nocturia. It affects individuals of all ages and can predispose affected individuals to depression and anxiety. However, few studies have been conducted on this topic. The objective of this study was to perform a systematic review and meta-analysis assessing the symptoms of depression, anxiety, and OAB using validated instruments. METHODS: The search for articles was based on the following descriptors: overactive bladder, depression, and anxiety ("Urinary bladder, Overactive AND Depression and Anxiety") OR ("Urinary bladder, Overactive AND Depression" OR "Urinary bladder, Overactive AND Anxiety")...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954461/seasonal-changes-in-lower-urinary-tract-symptoms-in-japanese-men-with-benign-prostatic-hyperplasia-treated-with-%C3%AE-1-blockers
#8
Minoru Kobayashi, Akinori Nukui, Takao Kamai
PURPOSE: To investigate whether seasonal changes occurred in lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). METHODS: Patients aged 50 years and older with BPH treated with α1-blockers were enrolled. The International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum and average flow rate, voided volume, and postvoid residual volume were measured in summer and winter. RESULTS: A total of 164 patients were enrolled...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954460/clean-intermittent-self-catheterization-as-a-treatment-modality-for-urinary-retention-perceptions-of-urologists
#9
Laurens Weynants, François Hervé, Veerle Decalf, Candy Kumps, Ronny Pieters, Bart de Troyer, Karel Everaert
PURPOSE: Clean intermittent self-catheterization (CISC) is now considered the gold standard for the management of urinary retention. In the literature, several articles on patients' perspectives on CISC and adherence to this technique have been published. No studies have yet explored the points of view of professional caregivers, such as nurses and doctors. The aim of this study was to explore the opinions of urologists about CISC and to evaluate the need for dedicated nurses specialized in CISC through a self-administered questionnaire...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954459/clinical-significance-of-periurethral-calcification-according-to-the-location-in-men-with-lower-urinary-tract-symptoms-and-a-small-prostate-volume
#10
Jang Hee Han, Joo Yong Lee, Jong Kyu Kwon, Jong Soo Lee, Kang Su Cho
PURPOSE: To assess the impact of periurethral calcification (PUC) according to its location on uroflowmetric parameters and urinary symptoms in patients with small prostate volume (PV). METHODS: Records were obtained from a prospectively maintained database of first-visit men with lower urinary tract symptoms (LUTS). Patients whose PV was >30 mL were excluded to elucidate more clearly the impact of PUC on LUTS. A total of 539 patients were enrolled in the study...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954458/potential-biomarkers-for-diagnosis-of-overactive-bladder-patients-urinary-nerve-growth-factor-prostaglandin-e2-and-adenosine-triphosphate
#11
Yoon Seok Suh, Kwang Jin Ko, Tae Heon Kim, Hyo Serk Lee, Hyun Hwan Sung, Won Jin Cho, Munjae Lee, Kyu-Sung Lee
PURPOSE: This study aimed to investigate potential biomarkers for the diagnosis of overactive bladder (OAB). METHODS: A total of 219 subjects were enrolled and divided into 2 groups: OAB subjects (n=189) and controls without OAB symptoms (n=30). Three-day voiding diaries and questionnaires were collected, and urinary levels of nerve growth factor (NGF), prostaglandin E2, and adenosine triphosphate were measured and normalized to urine creatinine (Cr). Baseline characteristics and urinary levels of markers were analyzed...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28954457/fine-particulate-matter-and-urology-emphasis-on-the-lower-urinary-tract
#12
Jin Wook Kim
No abstract text is available yet for this article.
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673067/expected-next-generation-drugs-under-development-in-relation-to-voiding-symptoms
#13
REVIEW
Kyung Jin Chung, Benjamin I Chung
New drug development is a high-risk venture, but if successful, will bring great revenues to those willing to accept the risk. In the field of urology, in particular for lower urinary tract symptoms (LUTS), the recent successful landing of drugs (e.g., mirabegron, botulinum toxin A, and tadalafil) has resulted in increased interest in new drug development. Benign prostatic hyperplasia and overactive bladder syndrome, representative LUTS diseases, are attractive targets because of their prevalence and market size in the field of urology...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673066/extracellular-vesicles-as-a-source-of-urological-biomarkers-lessons-learned-from-advances-and-challenges-in-clinical-applications-to-major-diseases
#14
REVIEW
Ji-Young Choi, Sujin Kim, Hyo-Bum Kwak, Dong-Ho Park, Jae-Hyoung Park, Jeong-Seon Ryu, Chang-Shin Park, Ju-Hee Kang
Extracellular vesicles (EVs) not only eliminate unwanted molecular components, but also carry molecular cargo essential for specific intercellular communication mechanisms. As the molecular characteristics and biogenetical mechanisms of heterogeneous EVs are different, many studies have attempted to purify and characterize EVs. In particular, exosomal molecules, including proteins, lipids, and nucleic acids, have been suggested as disease biomarkers or therapeutic targets in various diseases. However, several unresolved issues and challenges remain despite these promising results, including source variability before the isolation of exosomes from body fluids, the contamination of proteins during isolation, and methodological issues related to the purification of exosomes...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673065/sociodemographic-factors-related-to-lower-urinary-tract-symptoms-in-men-a-korean-community-health-survey
#15
Jung Ki Jo, Kyu Shik Kim, Ji Won Nam, Bo Yul Choi, Hong Sang Moon
PURPOSE: This study estimated the prevalence of lower urinary tract symptoms (LUTS) in Korean men and the conditions for being diagnosed with or treated for LUTS/benign prostatic hyperplasia (BPH). METHODS: We analyzed cross-sectional data collected from 69,851 Korean men who were 40 years of age or older and had participated in the Korean Community Health Survey performed in 2011. Interviewers performed face-to-face surveys that included sociodemographic questions, the International Prostate Symptom Score (IPSS), and questions regarding whether the subjects had been diagnosed with or treated for LUTS/BPH...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673064/effects-of-acute-sacral-neuromodulation-at-different-frequencies-on-bladder-overactivity-in-pigs
#16
Xing Li, Limin Liao, Guoqing Chen, Zhaoxia Wang, Han Deng
PURPOSE: We investigated the effects of different stimulation frequencies on the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs. METHODS: Implant-driven stimulators were used to stimulate the S3 spinal nerve in 13 pigs. Cystometry was performed by infusing normal saline (NS) or acetic acid (AA). SNM (pulse width, 210 µsec) at frequencies ranging from 5 to 50 Hz was conducted at the intensity threshold at which observable perianal and/or tail movement was induced...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673063/a-study-of-clinical-predictors-associated-with-intrinsic-sphincter-deficiency-in-women-with-stress-urinary-incontinence
#17
Kyung Kgi Park, Sung Dae Kim, Jung-Sik Huh, Young-Joo Kim
PURPOSE: Recently, intrinsic sphincter deficiency (ISD) has been identified as one important factor in the outcome of stress urinary incontinence (SUI) related surgery. Clinical factors that can predict ISD are uncommon. The aim of this study was to determine predictive clinical factors for ISD in female patients with SUI. METHODS: The patients were classified into 3 groups according to the value of Valsalva leak point pressure (VLPP)>90 cm H2O (anatomical incontinence, AI), between 61 and 90 cm H2O (equivocal, EV), and <60 cm H2O (ISD)...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673062/long-term-outcomes-of-augmentation-enterocystoplasty-in-patients-with-end-stage-bladder-diseases-a-single-institute-experience-involving-102-patients
#18
Shu-Yu Wu, Yuan-Hong Jiang, Hann-Chorng Kuo
PURPOSE: Augmentation enterocystoplasty (AE) has been shown to improve clinical symptoms in patients with end-stage bladder disease (ESBD). Herein, we report the long-term outcomes of a series of patients with different etiologies of ESBD who received AE. METHODS: We retrospectively reviewed 102 patients with ESBD who received AE at the Hualien Tzu Chi General Hospital from 1992 to 2014. ESBD in this study was defined as including neurogenic lower urinary tract dysfunction (NLUTD) due to spinal cord injury (SCI) or myelomeningocele, inflammatory bladder disease (IBD), ESBD occurring after pelvic cancer surgery, and other etiologies...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673061/the-risk-of-upper-urinary-tract-involvement-in-patients-with-ketamine-associated-uropathy
#19
Chi-Hang Yee, Jeremy Yuen-Chun Teoh, Pui-Tak Lai, Vivian Yee-Fong Leung, Winnie Chiu-Wing Chu, Wai-Man Lee, Yuk-Him Tam, Chi-Fai Ng
PURPOSE: The aims of this study were to investigate the prevalence of upper tract involvement in ketamine-associated uropathy, and to determine the predictors of hydronephrosis in patients with a history of ketamine abuse. METHODS: This was a cross-sectional study of a prospective cohort of patients with ketamine-associated uropathy. Data including demographics, pattern of ketamine abuse, pelvic pain and urgency or frequency (PUF) symptom score, uroflowmetry (UFM) parameters, serum renal function, and liver function tests were collected...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28673060/urethral-closure-pressure-at-stress-a-predictive-measure-for-the-diagnosis-and-severity-of-urinary-incontinence-in-women
#20
Anne-Cécile Pizzoferrato, Arnaud Fauconnier, Xavier Fritel, Georges Bader, Philippe Dompeyre
PURPOSE: Maintaining urinary continence at stress requires a competent urethral sphincter and good suburethral support. Sphincter competence is estimated by measuring the maximal urethral closure pressure at rest. We aimed to study the value of a new urodynamic measure, the urethral closure pressure at stress (s-UCP), in the diagnosis and severity of female stress urinary incontinence (SUI). METHODS: A total of 400 women without neurological disorders were included in this observational study...
June 2017: International Neurourology Journal
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