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Asian Pacific Journal of Tropical Medicine

Yi-Gang Yin, Ru-Zhu Wang, Zhong-Bao Ruan, Li Zhu
No abstract text is available yet for this article.
July 2017: Asian Pacific Journal of Tropical Medicine
Mubbashir Hussain, Shahzad Munir, Sultan Ayaz, Bahar Ullah Khattak, Taj Ali Khan, Niaz Muhammad, Muhammad Anees, Hazir Rahman, Muhammad Qasim, Muhammad Ameen Jamal, Irfan Ahmed, Kashif Rahim, Humaira Mazhar, Noha Watanay, Mohamed Kasbari
OBJECTIVE: To report presence of Leishmania major in Khyber Pakhtunkhwa of Pakistan, where cutaneous leishmaniasis (CL) is endemic and was thought to be caused by Leishmania tropica only. METHODS: Biopsy samples from 432 CL suspected patients were collected from 3 southern districts of Khyber Pakhtunkhwa during years 2011-2016. Microscopy on Giemsa stained slides were done followed by amplification of the ribosomal internal transcribed spacer 1 gene. RESULTS: Leishmania amastigotes were detected by microscopy in 308 of 432 samples (71...
July 2017: Asian Pacific Journal of Tropical Medicine
Xiao Liang, Hao Shen, Wei-Dong Shi, Shan Ren, Wei Jiang, Hao Liu, Peng Yang, Zhi-Yong Sun, Jun Lin, Hui-Lin Yang
OBJECTIVE: To assess the effects of axial vibrations on gene expression and lumbar intervertebral disc degeneration in vivo. METHODS: A modified bipedal rat model was established using a brachial plexus rhizotomy approach to imitate human upright posture. The experimental animals were randomly divided into three groups: control, vertical vibration, and whole-body vibration. Gene expression in degeneration of the intervertebral discs was assessed by reverse transcription-quantitative polymerase chain reaction...
July 2017: Asian Pacific Journal of Tropical Medicine
Ze-Quan Xu, Xu-Hua Song, Wen-Zhe Li, Yan Dou, Qiang Wu
OBJECTIVE: To compare patient-reported outcomes after implantation of the ZA9003 intraocular lens (IOLs), or the MCX11 ASP IOLs or the spherical IOLs (HQ-201HEP). METHODS: Prospective nonrandomized controlled trial was used. A total of 105 patients (210 eyes) were divided into three groups according to the type of IOLs: ZA9003 (35 patients, 70 eyes), MCX11 ASP (35 patients, 70 eyes) or HQ-201HEP (35 patients, 70 eyes). The main outcome was scores of Catquest nine-item short-form questionnaire...
July 2017: Asian Pacific Journal of Tropical Medicine
Imran Shahid, Waleed Hassan AlMalki, Mohammed Wanees AlRabia, Mohammed Hasan Mukhtar, Shaia Saleh R Almalki, Saad Ahmed Alkahtani, Sami S Ashgar, Hani S Faidah, Muhammad Hassan Hafeez
OBJECTIVE: To explore inhibitory effects of genome-specific, chemically synthesized siRNAs (small interference RNA) against NS3 gene of hepatitis C virus (HCV) 1a genotype in stable Huh-7 (human hepatoma) cells as well as against viral replication in serum-inoculated Huh-7 cells. METHODS: Stable Huh-7 cells persistently expressing NS3 gene were produced under antibiotic gentamycin (G418) selection. The cell clones resistant to 1000 μg antibiotic concentration (G418) were picked as stable cell clones...
July 2017: Asian Pacific Journal of Tropical Medicine
Hai-Zhi Liu, Xiao-Xue Han, Jia Liu, Feng-Cheng Zhu, Rui-Man Li
OBJECTIVE: To study the effect of Taoren Quyu Decoction (TQD) on endometrial cells in patients with endometriosis (EMs) and EMs in rats. METHODS: A total of 60 female Wistar rats were randomly divided into 4 groups, namely, normal group, model group, positive group and TQD group, each group having 15 rats. Except the normal group, EMs model was established in the other three groups by transplanting the rat autologous endometrium. After 4 weeks of intragastric administration, blood, eutopic and ectopic endometrial tissues of rats in each group were collected to detect the serum levels of estrogen (E2), cancer antigen 125 (CA125), endometrial antibody (EMAb), and expressions of microvessel density (MVD), vascular endothelial growth factor (VEGF) and angiopoietin (Ang-2)...
July 2017: Asian Pacific Journal of Tropical Medicine
Roslinah Mohamad Hussain, Zayan Nabilah Rasyidah Abd Razak, Wan Mazlina Md Saad, Maimunah Mustakim
OBJECTIVE: To investigate the effects of Andrographis paniculata (Burm.f.) Wall. Ex Nees (A. paniculata) on expressions and activities of catalase, superoxide dismutase and alkylhydroperoxide reductase C in Staphylococcus aureus (S. aureus) with respect to its survival in vitro. METHODS: Antioxidative property of methanolic leaves extract of A. paniculata (0.06 mg/mL). Minimum inhibitory concentration (MIC) was determined by its ability to reduce hydrogen peroxide (H2O2) toxicity against S...
July 2017: Asian Pacific Journal of Tropical Medicine
Ya-Ping Li, Lin Zhang, Yu-Liang Zou, Yan Yu
OBJECTIVES: To discuss the association between FGFR4 gene polymorphism rs351855 (Glu388Aly) and the susceptibility and chemotherapeutic effect of cervical cancer infected by high-risk type HPV. METHODS: A total of 162 patients with high-risk HPV cervical cancer and 162 healthy women were collected and the genotypes of the FGFR4 rs351855 locus were detected. The genotype distributions in the two groups were compared. The cervical cancer patients were divided into four groups which namely good therapeutic effect group and bad therapeutic effect, recurrence or metastasis and no recurrence or metastasis group respectively, and the risks of different genotype on the curative effect and prognosis were analyzed by Logistic regression...
July 2017: Asian Pacific Journal of Tropical Medicine
Fanyana M Mtunzi, Ikechukwu P Ejidike, Imelda Ledwaba, Aroke Ahmed, Vusumzi E Pakade, Michael J Klink, Sekomeng J Modise
OBJECTIVE: To evaluate the biological activities of Combretum erythrophyllum (C. erythrophyllum) leaf extracts against infectious diseases' pathogenesis and their cytotoxicity potentials. METHODS: Powdered leaf material (300 g) of C. erythrophyllum was extracted (1:10 w/v) using acetone to obtain the crude extract. Liquid-liquid fractionation was performed on the crude acetone extract (30 g) using solvents of different polarity. The bioautographic method was used to detect the inhibition of bacterial and fungal growth by active compounds present in the crude and fractions...
July 2017: Asian Pacific Journal of Tropical Medicine
Wei Huang, Jian-Qing Wang, Hai-Yan Song, Qian Zhang, Guang-Fa Liu
OBJECTIVE: To find a natural plant essential oil (EO) with excellent antimicrobial effects on food-borne bacteria and to explore the mechanism of its antimicrobial function against Escherichia coli (E. coli). METHODS: The antimicrobial activity of seven EOs against Gram-negative E. coli ATCC 8739 and Gram-positive Staphylococcus aureus ATCC 6538 was investigated using agar disk diffusion method, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of each EO was determined using the broth dilution method...
July 2017: Asian Pacific Journal of Tropical Medicine
Samah A El-Newary, Abeer Y Ibrahim, Mohsen S Asker, Manal G Mahmoud, Mohamed E El Awady
OBJECTIVE: To evaluate in-vitro antioxidant, anti-inflammatory and antitumor abilities against human breast adenocarcinoma (MCF7) and human prostate cancer (PC3) as well as the suppressor effect of bacterial exopolysaccharide (BAEPS) on Ehrlich ascites carcinoma (EAC). METHODS: In-vitro antioxidants characters of BAEPS were determined using various methods, while anti-inflammatory activity was estimated against cyclooxygenase (COX-1 and COX-2). In-vitro study, anticancer against MCF7 and PC3 were assessed by the mitochondrial dependent reduction of yellow MTT...
July 2017: Asian Pacific Journal of Tropical Medicine
Bimal Kumar Ghimire, Ji Hye Yoo, Chang Yeon Yu, Ill-Min Chung
OBJECTIVE: To investigate the composition of volatile compounds in the different accessions of Perilla frutescens (P. frutescens) collected from various habitats of China and Japan. METHODS: In the present study, the essential oil from the leaves of P. frutescens cultivars from China and Japan was extracted by hydro-distillation and the chemical composition and concentration of the volatile components present in the oils were determined by gas chromatography-mass spectrometry (GC-MS) analysis...
July 2017: Asian Pacific Journal of Tropical Medicine
Azar Shokri, Mehdi Sharif, Saeed Hosseini Teshnizi, Shahabeddin Sarvi, Mohammad Taghi Rahimi, Azadeh Mizani, Ehsan Ahmadpour, Mahboobeh Montazeri, Ahmad Daryani
OBJECTIVE: To evaluate the overall prevalence of Toxoplasma gondii infection among birds and poultries in Iran. METHODS: Data were systematically collected from 1983 to 2016 in Iran on the following electronic databases: PubMed, Google Scholar, Science Direct, Scopus, Web of Science, Magiran, Irandoc, IranMedex, and Scientific Information Database. Additionally, the abstracts of national scientific congresses and dissertations were included. RESULTS: A total of 20 articles in the field of birds and poultries toxoplasmosis, totally examining 4563 cases with 754 positive results reporting the overall prevalence of infection from all parts of Iran could fulfill our eligibility criteria...
July 2017: Asian Pacific Journal of Tropical Medicine
Baburajan Radha, Gnanaraj Muniraj
The proportion of the reported cases of Zika virus (ZIKV) infection reached the status of a pandemic. Numerous studies are being conducted on the isolation of ZIKV strains from various epidemics, diagnosis of the infections, various animal models and cell culture designs to study the pathogenesis of ZIKV in the attempts to find an effective ZIKV vaccine. This review focuses upon the 'Off-Spectrum' body of studies which analyses the epidemiology, pathogenesis and other attributes of ZIKV in the light of various dissident hypotheses...
July 2017: Asian Pacific Journal of Tropical Medicine
Raimunda Sâmia Nogueira Brilhante, Jamille Alencar Sales, Vandbergue Santos Pereira, Débora de Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro, Célia Maria de Souza Sampaio, Manoel de Araújo Neto Paiva, João Bosco Feitosa Dos Santos, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha
Moringa oleifera Lam (Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture...
July 2017: Asian Pacific Journal of Tropical Medicine
Hui Yu, Xian-Xian Zhao, Xing-Hua Shan, Pan Li, Tao Chen
No abstract text is available yet for this article.
June 2017: Asian Pacific Journal of Tropical Medicine
Zhen-Lv Lin, Guang-Wei Zheng, Lin Zhang, Jian-Tao Zheng, Hui Chen
No abstract text is available yet for this article.
June 2017: Asian Pacific Journal of Tropical Medicine
Yan Song, Jie-Ge Jiao, Ze-Jun Chen
In this article, based on the characteristics of tropical area, we analyze the beneficial and the disadvantage of tropical area to human health, points out the existing problems in elderly health management pattern in the tropics area, accordingly we discuss how to establish tropical characterized elderly health management, and put forward constructive suggestions.
June 2017: Asian Pacific Journal of Tropical Medicine
Somsri Wiwanitkit, Viroj Wiwanitkit
Sofosbuvir is a new antiviral drug that has been recommended for management of hepatitis C virus (HCV) for a few years. New researches support that sofosbuvir might be useful for the management of Zika virus infection. Based on the pharmacological activity, inhibiting the HCV RNA-dependent RNA polymerase (RdRp or NS5 protein), sofosbuvir is proposed for its effectiveness against Zika virus infection. Here, the authors used a mathematical modelling theoretical approach to predict the expected dosage of sofosbuvir for inhibiting Zika virus infection...
June 2017: Asian Pacific Journal of Tropical Medicine
Xiang-Ying Li, Jian-Qiang Chen, Yi-Kai Xu, Xiang-Jun Han
OBJECTIVE: To explore the magnetic resonance diffusion tensor imaging (MR-DTI) features of in the late stage of Wistar rat C6 brain glioma, and the relationship between fractional anisotropy value and tumor microarchitecture. METHODS: The concentration of more than 1.0 × 10(6)/10 μL glioma cells and complete medium were injected stereotactically into the right caudate nucleus of the experimental group (n = 35) and control group (n = 10), respectively. Conventional MRI, DTI, and enhanced T1WI scans were Performed using the GE Signa HD × 3...
June 2017: Asian Pacific Journal of Tropical Medicine
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