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Anesthesiology Research and Practice

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https://www.readbyqxmd.com/read/28539936/pregabalin-effect-on-acute-and-chronic-pain-after-cardiac-surgery
#1
Aik Bouzia, Vassilios Tassoudis, Menelaos Karanikolas, George Vretzakis, Argyro Petsiti, Nikolaos Tsilimingas, Elena Arnaoutoglou
Introduction. Pain after cardiac surgery affects long-term patient wellness. This study investigated the effect of preoperative pregabalin on acute and chronic pain after elective cardiac surgery with median sternotomy. Methods. Prospective double blind study. 93 cardiac surgery patients were randomly assigned into three groups: Group 1 received placebo, Group 2 received oral pregabalin 75 mg, and Group 3 received oral pregabalin 150 mg. Data were collected 8 hours, 24 hours, and 3 months postoperatively...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28487734/a-retrospective-analysis-of-oxygen-desaturation-during-acoustic-respiratory-rate-monitoring-in-non-icu-patients-following-tracheal-extubation-after-general-anesthesia
#2
Hideaki Kawanishi, Satoki Inoue, Masahiko Kawaguchi
Purpose. Acoustic respiratory rate (RRa) monitoring provides an accurate estimation of the respiratory rate (RR). We investigated the incidence of oxygen desaturation under RRa monitoring in a postoperative setting and identified its related factors. Methods. This study was a retrospective chart review of postoperative patients outside an intensive care unit setting. Using the data collected during the first 8 h postoperatively, patients were divided into oxygen desaturated (SpO2 < 90% for >10 s) and nondesaturated groups under oxygen administration...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28469670/the-effect-of-tracheal-intubation-induced-autonomic-response-on-photoplethysmography
#3
Pekka Talke
Introduction. Intraoperative stress responses and postoperative pain can be monitored using photoplethysmography (PPG). PPG signal has two components, AC and DC. Effects of noxious stimuli-induced stress responses have not been studied on the DC component of PPG. The aim of this study was to investigate the effect of a known noxious stimulus (endotracheal intubation) on both the AC and DC components of PPG. Methods. 15 surgical patients having general anesthesia were enrolled into this clinical study. PPG was recorded electronically from a pulse oximeter...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28321251/analgesic-effects-of-preincision-ketamine-on-postspinal-caesarean-delivery-in-uganda-s-tertiary-hospital-a-randomized-clinical-trial
#4
Richard Mwase, Tonny Stone Luggya, John Mark Kasumba, Humphrey Wanzira, Andrew Kintu, Joesph V B Tindimwebwa, Daniel Obua
Background. Good postoperative analgesic management improves maternal satisfaction and care of the neonate. Postoperative pain management is a challenge in Mulago Hospital, yet ketamine is accessible and has proven benefit. We determined ketamine's postoperative analgesic effects. Materials and Methods. We did an RCT among consenting parturients that were randomized to receive either intravenous ketamine (0.25 mg/kg) or placebo after spinal anesthetic. Pain was assessed every 30 mins up to 24 hours postoperatively using the numerical rating scale...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28210272/injectable-anesthesia-for-mice-combined-effects-of-dexmedetomidine-tiletamine-zolazepam-and-butorphanol
#5
Laura A Cagle, Lisa M Franzi, Steven E Epstein, Philip H Kass, Jerold A Last, Nicholas J Kenyon
Anesthetic protocols for murine models are varied within the literature and medetomidine has been implicated in the development of urethral plugs in male mice. Our objective was to evaluate the combination of butorphanol, dexmedetomidine, and tiletamine-zolazepam. A secondary objective was to identify which class of agent was associated with urethral obstructions in male mice. BALB/c male (n = 13) and female (n = 23) mice were assigned to dexmedetomidine and tiletamine-zolazepam with or without butorphanol or to single agent dexmedetomidine or tiletamine-zolazepam...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27974889/regional-anaesthesia-is-associated-with-shorter-postanaesthetic-care-and-less-pain-than-general-anaesthesia-after-upper-extremity-surgery
#6
Sven Grauman, Jakob Boethius, Joakim Johansson
Introduction. For surgery on the upper extremity, the anaesthetist often has a choice between regional anaesthesia (RA) and general anaesthesia (GA). We sought to investigate the possible differences between RA and GA after upper extremity surgery with regard to postoperative patient comfort. Methods. This is a retrospective observational study that was performed at an acute care secondary referral centre. One hundred and eighty-seven procedures involving orthopaedic surgery on the upper extremity were included...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27895665/sugammadex-enhanced-neuronal-apoptosis-following-neonatal-sevoflurane-exposure-in-mice
#7
Maiko Satomoto, Zhongliang Sun, Yushi U Adachi, Koshi Makita
In rodents, neonatal sevoflurane exposure induces neonatal apoptosis in the brain and results in learning deficits. Sugammadex is a new selective neuromuscular blockade (NMB) binding agent that anesthesiologists can use to achieve immediate reversal of an NMB with few side effects. Given its molecular weight of 2178, sugammadex is thought to be unable to pass through the blood brain barrier (BBB). Volatile anesthetics can influence BBB opening and integrity. Therefore, we investigated whether the intraperitoneal administration of sugammadex could exacerbate neuronal damage following neonatal 2% sevoflurane exposure via changes in BBB integrity...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27882047/perioperative-elevation-in-cell-free-dna-levels-in-patients-undergoing-cardiac-surgery-possible-contribution-of-neutrophil-extracellular-traps-to-perioperative-renal-dysfunction
#8
Yu Qi, Tokujiro Uchida, Mamoru Yamamoto, Yudai Yamamoto, Koji Kido, Hiroyuki Ito, Nagara Ohno, Miho Asahara, Yoshitsugu Yamada, Osamu Yamaguchi, Chieko Mitaka, Makoto Tomita, Koshi Makita
Background. This study aimed to determine the perioperative change in serum double-strand DNA (dsDNA) as a marker potentially reflecting neutrophil extracellular trap concentration in samples from patients undergoing cardiac surgery and to analyze a relationship between serum dsDNA concentrations and perioperative renal dysfunction. Methods. Serum dsDNA concentrations in samples that were collected during a previously conducted, prospective, multicenter, observational study were measured. Eighty patients undergoing elective cardiac surgery were studied...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27847515/the-ambu%C3%A2-aura-i%C3%A2-laryngeal-mask-and-lma-supreme%C3%A2-a-randomized-trial-of-clinical-performance-and-fibreoptic-positioning-in-unparalysed-anaesthetised-patients-by-novices
#9
Zanahriah Yahaya, Wendy H Teoh, Nora A Dintan, Ravi Agrawal
Introduction. Manikin studies' data cannot accurately be extrapolated to real-life scenarios and inherent differences in design and materials of newer products may affect their clinical performance. Methods. Hence, we compared the AMBU® Aura-i™ and LMA Supreme™ in this randomized trial involving 100 ASA 1-2 unparalysed anaesthetised patients undergoing minor gynaecological surgery. Investigators had <20 Aura-i insertions. Primary outcome was time to achieve effective ventilation and secondarily insertion parameters, oropharyngeal leak pressures (OLP), fibreoptic positioning, and pharyngeal morbidity...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27818682/current-trends-in-neuromuscular-blockade-management-and-monitoring-amongst-singaporean-anaesthetists
#10
Wendy H Teoh, Thomas Ledowski, Phillip S Tseng
Introduction. This survey aimed to investigate the attitudes/practice pertaining the use, management, and monitoring of neuromuscular blockade amongst Singaporean anaesthetists. Methods. All specialist accredited anaesthetists registered with the Singapore Medical Council were invited to complete an anonymous online survey. Results. The response rate was 39.5%. Neuromuscular monitoring (NM) was used routinely by only 13.1% despite the widespread availability of monitors. 82% stated residual NMB (RNMB) was a significant risk factor for patient outcome, but only 24% believed NMB monitoring should be compulsory in all paralyzed patients...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27777585/time-trends-and-predictors-of-abnormal-postoperative-body-temperature-in-infants-transported-to-the-intensive-care-unit
#11
Hedwig Schroeck, Angela K Lyden, Wendy L Benedict, Satya Krishna Ramachandran
Background. Despite increasing adoption of active warming methods over the recent years, little is known about the effectiveness of these interventions on the occurrence of abnormal postoperative temperatures in sick infants. Methods. Preoperative and postoperative temperature readings, patient characteristics, and procedural factors of critically ill infants at a single institution were retrieved retrospectively from June 2006 until May 2014. The primary endpoints were the incidence and trend of postoperative hypothermia and hyperthermia on arrival at the intensive care units...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27635132/hypnosis-in-the-perioperative-management-of-breast-cancer-surgery-clinical-benefits-and-potential-implications
#12
REVIEW
Arnaud Potié, Fabienne Roelants, Audrey Pospiech, Mona Momeni, Christine Watremez
The aim of this review is to summarize data published on the use of perioperative hypnosis in patients undergoing breast cancer surgery (BCS). Indeed, the majority of BCS patients experience stress, anxiety, nausea, vomiting, and pain. Correct management of the perioperative period and surgical removal of the primary tumor are clearly essential but can affect patients on different levels and hence have a negative impact on oncological outcomes. This review examines the effect of clinical hypnosis performed during the perioperative period...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27630712/the-effect-of-dexmedetomidine-on-lumbar-epidural-injection-for-failed-back-surgery-syndrome
#13
Ashraf Eskandr, Sadik Abdel Maseeh
Purpose. Failed back surgery syndrome is a chronic pain condition requiring rapid, effective, and efficient management. This study evaluates the effect of adding dexmedetomidine to lumbar epidural steroids in patients with failed back surgery syndrome. Methods. Fifty patients suffering from failed back surgery syndrome were randomly assigned to one of two groups, receiving an epidural injection of 20 mL of either a mixture of betamethasone (14 mg) and bupivacaine 0.5 mg (group C) or a mixture of betamethasone (14 mg), bupivacaine 0...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27610133/length-of-stay-in-ambulatory-surgical-oncology-patients-at-high-risk-for-sleep-apnea-as-predicted-by-stop-bang-questionnaire
#14
Diwakar D Balachandran, Saadia A Faiz, Mike Hernandez, Alicia M Kowalski, Lara Bashoura, Farzin Goravanchi, Sujith V Cherian, Elizabeth Rebello, Spencer S Kee, Katy E French
Background. The STOP-BANG questionnaire has been used to identify surgical patients at risk for undiagnosed obstructive sleep apnea (OSA) by classifying patients as low risk (LR) if STOP-BANG score < 3 or high risk (HR) if STOP-BANG score ≥ 3. Few studies have examined whether postoperative complications are increased in HR patients and none have been described in oncologic patients. Objective. This retrospective study examined if HR patients experience increased complications evidenced by an increased length of stay (LOS) in the postanesthesia care unit (PACU)...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27478436/intubation-success-through-i-gel%C3%A2-and-intubating-laryngeal-mask-airway%C3%A2-using-flexible-silicone-tubes-a-randomised-noninferiority-trial
#15
Latha Naik, Neerja Bhardwaj, Indu Mohini Sen, Rakesh V Sondekoppam
Introduction. The study aims to test whether flexible silicone tubes (FST) improve performance and provide similar intubation success through I-Gel as compared to ILMA. Our trial is registered in CTRI and the registration number is "CTRI/2016/06/006997." Methods. One hundred and twenty ASA status I-II patients scheduled for elective surgical procedures needing tracheal intubation were randomised to endotracheal intubation using FST through either I-Gel or ILMA. In the ILMA group (n = 60), intubation was attempted through ILMA using FST and, in the I-Gel group (n = 60), FST was inserted through I-Gel airway...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27429615/the-effect-of-patient-weight-and-provider-training-and-experience-on-dosing-of-rocuronium
#16
N C Godwin, L Rodriguez, S Banks, B T Major, Y Rodriguez
Introduction. Maintenance dosing of neuromuscular blocking agents is complex and varies with patient, procedure, and clinical situation. With this in mind, we sought to identify factors impacting the maintenance dosing of neuromuscular blockers as a step toward identifying best practice with respect to minimizing residual neuromuscular blockade. Methods. Cases utilizing rocuronium from July 1, 2010, to June 30, 2014, at the sponsoring institution were analyzed. Using a mixed model to account for repeated measures, patients were analyzed by dose and weight category as defined by the World Health Organization (eight categories ranging from very severely underweight to very severely obese) as well as by the administering provider's level of experience...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27382368/comparison-of-medical-adhesive-tapes-in-patients-at-risk-of-facial-skin-trauma-under-anesthesia
#17
Ling Antonia Zeng, Sui An Lie, Shin Yuet Chong
Introduction. Adhesive tapes are used for taping eyelids closed and securing endotracheal tubes during general anesthesia. These tapes can cause facial skin injury. We compared the incidence of facial skin injury and patient satisfaction with different tapes used. Methods. A total of 60 adult patients at risk of skin trauma were randomized to use 3M™ Kind Removal Silicone Tape or standard acrylate tapes: 3M Durapore (endotracheal tube) and Medipore (eyelids). Patients were blinded to tape used. Postoperatively, a blinded recovery nurse assessed erythema, edema, and denudation of skin...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27313608/effects-of-addition-of-systemic-tramadol-or-adjunct-tramadol-to-lidocaine-used-for-intravenous-regional-anesthesia-in-patients-undergoing-hand-surgery
#18
Abdulkadir Yektaş, Funda Gümüş, Abdulhalim Karayel, Ayşin Alagöl
Intravenous regional anesthesia (IVRA) is used in outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages. The present study aimed to investigate the effects of addition of systemic tramadol or adjunct tramadol to lidocaine for IVRA in patients undergoing hand surgery. American Society of Anesthesiologists (ASA) I-II patients (n = 60) who underwent hand surgery were included. For this purpose, only lidocaine (LDC), lidocaine+adjunct tramadol (LDC+TRA group), or lidocaine+systemic tramadol (LDC+SysTRA group) was administered to the patients for IVRA and the groups were compared in terms of onset and recovery time of sensory and motor blocks, quality of anesthesia, and the degree of intraoperative and postoperative pain...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27293430/development-and-testing-of-screen-based-and-psychometric-instruments-for-assessing-resident-performance-in-an-operating-room-simulator
#19
Richard R McNeer, Roman Dudaryk, Nicholas B Nedeff, Christopher L Bennett
Introduction. Medical simulators are used for assessing clinical skills and increasingly for testing hypotheses. We developed and tested an approach for assessing performance in anesthesia residents using screen-based simulation that ensures expert raters remain blinded to subject identity and experimental condition. Methods. Twenty anesthesia residents managed emergencies in an operating room simulator by logging actions through a custom graphical user interface. Two expert raters rated performance based on these entries using custom Global Rating Scale (GRS) and Crisis Management Checklist (CMC) instruments...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27293429/comparison-of-the-success-of-two-techniques-for-the-endotracheal-intubation-with-c-mac-video-laryngoscope-miller-blade-in-children-a-prospective-randomized-study
#20
Renu Sinha, Ankur Sharma, Bikash Ranjan Ray, Ravinder Kumar Pandey, Vanlalnghka Darlong, Jyotsna Punj, Chandralekha Chandralekha, Ashish Datt Upadhyay
Background. Ease of endotracheal intubation with C-MAC video laryngoscope (VLS) with Miller blades 0 and 1 has not been evaluated in children. Methods. Sixty children weighing 3-15 kg with normal airway were randomly divided into two groups. Intubation was done with C-MAC VLS Miller blade using either nonstyletted endotracheal tube (ETT) (group WS) or styletted ETT (group S). The time for intubation and total procedure, intubation attempts, failed intubation, blade repositioning or external laryngeal maneuver, and complications were recorded...
2016: Anesthesiology Research and Practice
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