journal
MENU ▼
Read by QxMD icon Read
search

World Journal of Hepatology

journal
https://www.readbyqxmd.com/read/29988922/systematic-review-of-the-outcomes-of-surgical-resection-for-intermediate-and-advanced-barcelona-clinic-liver-cancer-stage-hepatocellular-carcinoma-a-critical-appraisal-of-the-evidence
#1
Ye Xin Koh, Hwee Leong Tan, Weng Kit Lye, Juinn Huar Kam, Adrian Kah Heng Chiow, Siong San Tan, Su Pin Choo, Alexander Yaw Fui Chung, Brian Kim Poh Goh
AIM: To perform a systematic review to determine the survival outcomes after curative resection of intermediate and advanced hepatocellular carcinomas (HCC). METHODS: A systematic review of the published literature was performed using the PubMed database from 1st January 1999 to 31st Dec 2014 to identify studies that reported outcomes of liver resection as the primary curative treatment for Barcelona Clinic Liver Cancer (BCLC) stage B or C HCC. The primary end point was to determine the overall survival (OS) and disease free survival (DFS) of liver resection of HCC in BCLC stage B or C in patients with adequate liver reserve ( i...
June 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29988878/paracentesis-in-cirrhotics-is-associated-with-increased-risk-of-30-day-readmission
#2
Lindsay A Sobotka, Rohan M Modi, Akshay Vijayaraman, A James Hanje, Anthony J Michaels, Lanla F Conteh, Alice Hinton, Ashraf El-Hinnawi, Khalid Mumtaz
AIM: To determine the readmission rate, its reasons, predictors, and cost of 30-d readmission in patients with cirrhosis and ascites. METHODS: A retrospective analysis of the nationwide readmission database (NRD) was performed during the calendar year 2013. All adults cirrhotics with a diagnosis of ascites, spontaneous bacterial peritonitis, or hepatic encephalopathy were identified by ICD-9 codes. Multivariate analysis was performed to assess predictors of 30-d readmission and cost of readmission...
June 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29988862/responsibility-of-hepatitis-c-virus-in-the-development-of-hepatocellular-carcinoma-from-molecular-alterations-to-possible-solutions
#3
Gaetano Bertino, Giulia Malaguarnera, Evelise Frazzetto, Alice Sciuto, Gaetano Inserra, Guido Nicola Zanghì, Michele Malaguarnera
There are several causes of hepatocellular carcinoma (HCC), but certainly the hepatitis C virus (HCV) is one of the most common. The HCV is able to contribute, both directly and indirectly, to the development of HCC. Determining early HCV clearance before an advanced liver disease develops, is absolutely necessary as this prevents the initiation of the cascade of events induced by HCV that may result in the development of HCC. The early treatment of the infection and the clearance of HCV represents today, in the age of the direct antiviral agents (DAAs), an extraordinary opportunity for true prevention of the development of HCV-related HCC...
June 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29844855/isolated-hepatic-non-obstructive-sinusoidal-dilatation-20-year-single-center-experience
#4
Dharma Budi Sunjaya, Guilherme Piovezani Ramos, Manuel Bonfim Braga Neto, Ryan Lennon, Taofic Mounajjed, Vijay Shah, Patrick Sequeira Kamath, Douglas Alano Simonetto
AIM: To characterize isolated non-obstructive sinusoidal dilatation (SD) by identifying associated conditions, laboratory findings, and histological patterns. METHODS: Retrospectively reviewed 491 patients with SD between 1995 and 2015. Patients with obstruction at the level of the small/large hepatic veins, portal veins, or right-sided heart failure were excluded along with history of cirrhosis, hepatic malignancy, liver transplant, or absence of electrocardiogram/cardiac echocardiogram...
May 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29844854/clinical-epidemiology-of-chronic-viral-hepatitis-b-a-tuscany-real-word-large-scale-cohort-study
#5
Cristina Stasi, Caterina Silvestri, Roberto Berni, Maurizia Rossana Brunetto, Anna Linda Zignego, Cristina Orsini, Stefano Milani, Liana Ricciardi, Andrea De Luca, Pierluigi Blanc, Cesira Nencioni, Donatella Aquilini, Alessandro Bartoloni, Giampaolo Bresci, Santino Marchi, Franco Filipponi, Piero Colombatto, Paolo Forte, Andrea Galli, Sauro Luchi, Silvia Chigiotti, Alessandro Nerli, Giampaolo Corti, Rodolfo Sacco, Paola Carrai, Angelo Ricchiuti, Massimo Giusti, Paolo Almi, Andrea Cozzi, Silvia Carloppi, Giacomo Laffi, Fabio Voller, Francesco Cipriani
AIM: To build a regional database of chronic patients to define the clinical epidemiology of hepatitis B virus (HBV)-infected patients in the Tuscan public health care system. METHODS: This study used a cross-sectional cohort design. We evaluated chronic viral hepatitis patients with HBV referred to the outpatient services of 16 hospital units. Information in the case report forms included main demographic data, blood chemistry data, viral hepatitis markers, instrumental evaluations, and eligibility for treatment or ongoing therapy and liver transplantation...
May 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29713398/review-of-the-literature-laparoscopic-surgery-for-metastatic-hepatic-leiomyosarcoma-associated-with-smooth-muscle-tumor-of-uncertain-malignant-potential-case-report
#6
Keisuke Fukui, Nobuhisa Takase, Taiichiro Miyake, Koji Hisano, Eri Maeda, Tohru Nishimura, Koichiro Abe, Akihito Kozuki, Tomohiro Tanaka, Naoki Harada, Manabu Takamatsu, Kunihiko Kaneda
Metastatic hepatic leiomyosarcoma is a rare malignant smooth muscle tumor. We report a case of metastatic hepatic leiomyosarcoma associated with smooth muscle tumor of uncertain malignant potential (STUMP). A 68-year-old female presented with a liver mass (60 mm × 40 mm, Segment 4). She underwent left salpingo-oophorectomy for an ovary tumor with STUMP in a broad ligament 6 years ago. Though FDG-PET showed obvious metabolically active foci, abnormal metabolically active foci other than the lesion were not detected...
April 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29601073/do-ayurveda-drugs-induce-liver-injury
#7
COMMENT
Galib Ruknuddin
Drugs fulfilling the criterion of a standard drug will always become panacea provided, if they are used properly. On the other hand, a poorly manufactured drug however used skillfully, will prove to be a poison. Texts of Ayurveda, do mention hazards of drugs, which are not properly manufactured or administered. Art of drug administration is unique in this ancient medical science that cautions towards concentrating on dose, indications, contra-indications, suitable vehicle, specific diet, certain restrictions etc ...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29599903/liver-failure-caused-by-prolonged-state-of-malnutrition-following-bariatric-surgery
#8
Willem J Lammers, Antonie Jp van Tilburg, Jan A Apers, Janneke Wiebolt
Bariatric surgery is an effective tool in the treatment of patients with morbid obesity. In these case reports we describe 2 patients who developed liver failure after currently-practiced types of bariatric surgery, caused by a prolonged state of malnutrition provoked by psychiatric problems. Despite intensive guidance of a psychologist and dieticians after surgery, our patients deteriorated psychologically, resulting in a prolonged state of severe malnutrition and anorexia. Finally, a state of starvation was reached, passing a critical level of the liver capacity...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29599902/clostridium-paraputrificum-septicemia-and-liver-abscess
#9
Yong K Kwon, Faiqa A Cheema, Bejon T Maneckshana, Caroline Rochon, Patricia A Sheiner
We report the first case of a healthy 23-year-old female who underwent an interventional radiology-guided embolization of a hepatic adenoma, which resulted in a gas forming hepatic liver abscess and septicemia by Clostridium paraputrificum . A retrospective review of Clostridial liver abscesses was performed using a PubMed literature search, and we found 57 clostridial hepatic abscess cases. The two most commonly reported clostridial species are C. perfringens and C. septicum (64.9% and 17.5% respectively)...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29599901/management-of-restless-legs-syndrome-in-chronic-liver-disease-a-challenge-for-the-correct-diagnosis-and-therapy
#10
Rita Moretti, Paola Caruso, Marzia Tecchiolli, Silvia Gazzin, Claudio Tiribelli
AIM: To investigate the association between restless legs syndrome (RLS) and well-defined chronic liver disease, and the possible therapeutic options. METHODS: Two hundred and eleven patients with chronic liver disease, complaining of sleep disturbances, painful leg sensation and daily sleepiness, were included. Patients with persistent alcohol intake, recent worsening of clinical conditions, or hepatitis C virus were excluded. Diagnosis of RLS was suggested by the Johns Hopkins questionnaire and verified by fulfilling the diagnostic criteria by Allen...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29599900/metabolomics-from-liver-chiromancy-to-personalized-precision-medicine-in-advanced-chronic-liver-disease
#11
REVIEW
Bogdan Procopet, Petra Fischer, Oana Farcau, Horia Stefanescu
Currently there is a lack of accurate biomarkers for diagnosis and prognosis in advanced liver diseases. Either the occurrence of first decompensation, or diagnosis of acute on chronic liver failure, severe alcoholic hepatitis, or hepatocellular carcinoma (HCC), none of the available biomarkers are satisfactory. Metabolomics is the newest of omics, being much closer than the others to the actual phenotype and pathologic changes that characterizes a certain condition. It deals with a much wider spectrum of low molecular weight bio-compounds providing a powerful platform for discovering novel biomarkers and biochemical pathways to improve diagnostic, prognostication and therapy...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29599899/reactivation-of-hepatitis-b-after-liver-transplantation-current-knowledge-molecular-mechanisms-and-implications-in-management
#12
REVIEW
Ranjit Chauhan, Shilpa Lingala, Chiranjeevi Gadiparthi, Nivedita Lahiri, Smruti R Mohanty, Jian Wu, Tomasz I Michalak, Sanjaya K Satapathy
Chronic hepatitis B (CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma (HCC). Liver transplantation (LT) is considered gold standard for treatment of hepatitis B virus (HBV)-related liver failure and HCC. However, post-transplant viral reactivation can be detrimental to allograft function, leading to poor survival. Prophylaxis with high-dose hepatitis B immunoglobulin (HBIG) and anti-viral drugs have achieved remarkable progress in LT by suppressing viral replication and improving long-term survival...
March 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527270/primary-hepatic-peripheral-t-cell-lymphoma-associated-with-epstein-barr-viral-infection
#13
Daryl Ramai, Emmanuel Ofori, Sofia Nigar, Madhavi Reddy
Primary hepatic peripheral T-cell lymphoma (H-PTCL) is one of the rarest forms of non-Hodgkin lymphoma. We report a patient who presented with worsening jaundice, abdominal pain, and vomiting. Laboratory values were significant for elevated total bilirubin, alkaline phosphatase, and liver aminotransferases. Following a liver biopsy, histopathology revealed several large dense clusters of atypical T-lymphocytes which were CD2+, CD3+, CD5+, CD7-, CD4+, CD8-, CD56-, CD57-, CD30+ by immunohistochemistry. The proliferation index was approximately 70% by labeling for ki67/mib1...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527269/outcomes-of-kidney-transplantation-in-patients-with-hepatitis-b-virus-infection-a-systematic-review-and-meta-analysis
#14
Charat Thongprayoon, Wisit Kaewput, Konika Sharma, Karn Wijarnpreecha, Napat Leeaphorn, Patompong Ungprasert, Ankit Sakhuja, Franco H Cabeza Rivera, Wisit Cheungpasitporn
AIM: To assess outcomes of kidney transplantation including patient and allograft outcomes in recipients with hepatitis B virus (HBV) infection, and the trends of patient's outcomes overtime. METHODS: A literature search was conducted using MEDLINE, EMBASE and Cochrane Database from inception through October 2017. Studies that reported odds ratios (OR) of mortality or renal allograft failure after kidney transplantation in patients with HBV [defined as hepatitis B surface antigen (HBsAg) positive] were included...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527268/outcomes-assessment-of-hepatitis-c-virus-positive-psoriatic-patients-treated-using-pegylated-interferon-in-combination-with-ribavirin-compared-to-new-direct-acting-antiviral-agents
#15
Giovanni Damiani, Chiara Franchi, Paolo Pigatto, Andrea Altomare, Alessia Pacifico, Stephen Petrou, Sebastiano Leone, Maria Caterina Pace, Marco Fiore
AIM: To evaluate the outcomes in biological treatment and quality of life of psoriatic patients with chronic hepatitis C (CHC) treated with new Direct-Acting Antiviral agents (DAAs) compared to pegylated interferon-2α plus ribavirin (P/R) therapy. METHODS: This is a retrospective study involving psoriatic patients in biological therapy who underwent anti-hepatitis C virus (HCV) treatment at the Department of Dermatology Galeazzi Orthopaedic Institute Milan, Italy from January 2010 to November 2017...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527267/hepatitis-c-virus-knowledge-improves-hepatitis-c-virus-screening-practices-among-primary-care-physicians
#16
Sandeep T Samuel, Anthony D Martinez, Yang Chen, Marianthi Markatou, Andrew H Talal
AIM: To understand the role of knowledge as a promoter of hepatitis C virus (HCV) screening among primary care physicians (PCP). METHODS: A 45-item online questionnaire assessing knowledge of HCV natural history, risk factors, and treatment was distributed to 163 PCP. Logistic regression, adjusted for survey responses, assessed associations between PCP knowledge of HCV natural history and treatment and birth cohort ( i.e ., birth between 1945 and 1965) screening...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527266/survival-outcomes-of-liver-transplantation-for-hepatocellular-carcinoma-in-patients-with-normal-high-and-very-high-preoperative-alpha-fetoprotein-levels
#17
Wong Hoi She, Albert Chi Yan Chan, Tan To Cheung, Chung Mau Lo, Kenneth Siu Ho Chok
AIM: To investigate the impact of alpha-fetoprotein (AFP) on long-term recurrence rate and overall survival and we also aimed to define the level of AFP leading to a higher risk of disease recurrence and affecting patient survival. METHODS: Data of adult patients who received liver transplant (LT) for hepatocellular carcinoma (HCC) at our hospital from January 2000 to December 2013 were reviewed. Reviewed data included demographic characteristics, preoperative AFP level, operative details, follow-up details, and survival outcomes...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527265/morphological-and-biochemical-effects-of-weekend-alcohol-consumption-in-rats-role-of-concentration-and-gender
#18
José A Morales-González, María de Lourdes Sernas-Morales, Ángel Morales-González, Laura Ligía González-López, Eduardo Osiris Madrigal-Santillán, Nancy Vargas-Mendoza, Tomás Alejandro Fregoso-Aguilar, Liliana Anguiano-Robledo, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, Germán Chamorro-Cevallos
AIM: To examine the association between weekend alcohol consumption and the biochemical and histological alterations at two different concentrations of alcohol in both genders in rats. METHODS: Wistar rats weighing 170-200 g were divided into groups as follows: (1) Control groups; and (2) weekend alcohol-consumption group: 2 d/weekly per 12 wk, at two different concentrations: (1) Group of males or females with a consumption of a solution of alcohol at 40%; and (2) group of males or females with a consumption of a solution of alcohol at 5%...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527264/multipotent-stromal-cells-stimulate-liver-regeneration-by-influencing-the-macrophage-polarization-in-rat
#19
Andrey Elchaninov, Timur Fatkhudinov, Natalia Usman, Irina Arutyunyan, Andrey Makarov, Anastasia Lokhonina, Irina Eremina, Viktor Surovtsev, Dmitry Goldshtein, Galina Bolshakova, Valeria Glinkina, Gennady Sukhikh
AIM: To investigate the influence of the umbilical cord-derived multipotent stromal cells (MSCs) on recovery of the liver after the subtotal resection, that is, removal of 80% of the organ mass, a renowned model of the small-for-size liver remnant syndrome. METHODS: The MSCs were obtained from the intervascular tissue of umbilical cords, dissected from rat fetuses, by the explant culture technique. The vital labeling of MSCs with РКН26 was carried out on the 3rd passage...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29527263/homologous-recombination-mediates-stable-fah-gene-integration-and-phenotypic-correction-in-tyrosinaemia-mouse-model
#20
Norman Junge, Qinggong Yuan, Thu Huong Vu, Simon Krooss, Christien Bednarski, Asha Balakrishnan, Toni Cathomen, Michael P Manns, Ulrich Baumann, Amar Deep Sharma, Michael Ott
AIM: To stably correct tyrosinaemia in proliferating livers of fumarylacetoacetate-hydrolase knockout ( Fah -/-) mice by homologous-recombination-mediated targeted addition of the Fah gene. METHODS: C57BL/6 Fah∆exon5 mice served as an animal model for human tyrosinaemia type 1 in our study. The vector was created by amplifying human Fah cDNA including the TTR promoter from a lentivirus plasmid as described. The Fah expression cassette was flanked by homologous arms (620 bp and 749 bp long) of the Rosa26 gene locus...
February 27, 2018: World Journal of Hepatology
journal
journal
43059
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"