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Virulence

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https://www.readbyqxmd.com/read/28727942/dectin-1-embraces-candida-glabrata
#1
Carlos Del Fresno Sánchez
No abstract text is available yet for this article.
July 20, 2017: Virulence
https://www.readbyqxmd.com/read/28727941/mucin-1-is-a-novel-glycoprotein-involved-in-host-defense-against-invasive-pneumococcal-disease
#2
Jose Yuste
No abstract text is available yet for this article.
July 20, 2017: Virulence
https://www.readbyqxmd.com/read/28727933/genotype-specific-acquisition-evolution-and-adaptation-of-characteristic-mutations-in-hepatitis-e-virus
#3
Aqsa Ikram, Mohamad S Hakim, Jian-Hua Zhou, Wenshi Wang, Maikel P Peppelenbosch, Qiuwei Pan
Hepatitis E virus (HEV) infection is a major cause of acute hepatitis but also provokes chronic infection in immunocompromised patients. Although the pathogenesis and treatment outcome involve complex interplay between the virus and host, the nature of adaptive responses of HEV to the host immune system remain obscure at best. In this study, we employed large-scale proteomic bioinformatics to profile characteristic mutations in human HEV isolates associated to ribavirin treatment failure, chronic hepatitis, hepatic failure or altered immunoreactivity...
July 20, 2017: Virulence
https://www.readbyqxmd.com/read/28723316/when-green-and-red-mycology-meet-impressions-from-an-interdisciplinary-forum-on-virulence-mechanisms-of-phyto-and-human-pathogenic-fungi
#4
Yidong Yu, Bernhard Hube, Jörg Kämper, Vera Meyer, Sven Krappmann
Fungal infections pose a constant threat to plants and humans, but detailed knowledge about pathogenesis, immunity, or virulence is rather scarce. Due to the fact that a certain overlap in the armoury of infection exists between plant- and human-pathogenic fungi, an interdisciplinary forum was held in October 2016 at the Institute for Clinical Microbiology, Immunology and Hygiene in Erlangen under the organisational umbrella from two special interest groups of German microbial societies. Scientific exchange and intense discussion of this timely topic was fostered by bringing together renowned experts in their respective fields to present their thoughts and recent findings in the course of a plenary lecture and six themed sessions, accompanied by oral and poster contributions of young researchers...
July 19, 2017: Virulence
https://www.readbyqxmd.com/read/28723277/ns2a-comprises-a-putative-viroporin-of-dengue-virus-2
#5
Gaurav Shrivastava, Julio García-Cordero, Moisés León-Juárez, Goldie Oza, Jose Tapia-Ramírez, Nicolas Villegas-Sepulveda, Leticia Cedillo-Barrón
No abstract text is available yet for this article.
July 19, 2017: Virulence
https://www.readbyqxmd.com/read/28723236/selective-inhibition-of-host-cell-signaling-for-rotavirus-antivirals-pi3k-akt-mtor-mediated-rotavirus-pathogenesis
#6
Jason Kindrachuk
No abstract text is available yet for this article.
July 19, 2017: Virulence
https://www.readbyqxmd.com/read/28704618/paracoccidioides-brasiliensis-presents-metabolic-reprogramming-and-secretes-a-serine-proteinase-during-murine-infection
#7
Laurine Lacerda Pigosso, Lilian Cristiane Baeza, Mariana Vieira Tomazett, Mariana Batista Rodrigues Faleiro, Veridiana Maria Brianezi Dignani de Moura, Alexandre Melo Bailão, Clayton Luiz Borges, Juliana Alves Parente Rocha, Gabriel Rocha Fernandes, Gregory M Gauthier, Celia Maria de Almeida Soares
Paracoccidoides brasiliensis and Paracoccidioides lutzii, the etiologic agents of paracoccidioidomycosis, cause disease in healthy and immunocompromised persons in Latin America. We developed a method for harvesting P. brasiliensis yeast cells from infected murine lung to facilitate in vivo transcriptional and proteomic profiling. P. brasiliensis harvested at 6 h post-infection were analyzed using RNAseq and LC-MS(E). In vivo yeast cells had 594 differentially expressed transcripts and 350 differentially expressed proteins...
July 13, 2017: Virulence
https://www.readbyqxmd.com/read/28704162/thioester-containing-proteins-at-the-crossroads-of-immune-effector-mechanisms
#8
Ulrich Theopold, Martin Schmid
No abstract text is available yet for this article.
July 13, 2017: Virulence
https://www.readbyqxmd.com/read/28700262/the-sixth-sensor-a-candida-albicans-biofilm-master-regulator-that-responds-to-inter-kingdom-interactions
#9
Nicholas S Jakubovics
No abstract text is available yet for this article.
July 12, 2017: Virulence
https://www.readbyqxmd.com/read/28679067/depicting-the-metabolism-of-paracoccidioides-brasiliensis-during-infection-by-transcriptional-and-proteomic-approaches
#10
Angel Gonzalez
No abstract text is available yet for this article.
July 5, 2017: Virulence
https://www.readbyqxmd.com/read/28658597/galleria-mellonella-as-a-host-model-to-study-candida-glabrata-virulence-and-antifungal-efficacy
#11
Lauren Ames, Sarah Duxbury, Bogna Pawlowska, Hsueh-Lui Ho, Ken Haynes, Steven Bates
No abstract text is available yet for this article.
June 28, 2017: Virulence
https://www.readbyqxmd.com/read/28658594/targeting-protein-localization-for-anti-infective-therapy
#12
J Andrew Alspaugh
Invasive fungal infections are devastating complications of immunocompromised patients. These infections are notoriously difficult to treat given the surprising degree of physiological similarity between fungi and the infected mammalian host. To explore novel targets for antifungal therapy, investigators have studied enzymes involved in the post-translational modification of highly conserved signaling proteins such as the Ras-like GTPases. These modifications are often required for protein localization and function...
June 28, 2017: Virulence
https://www.readbyqxmd.com/read/28658592/dectin-1-plays-an-important-role-in-host-defense-against-systemic-candida-glabrata-infection
#13
Si Min Chen, Shen Hui, Teng Zhang, Xin Huang, Xiao Qi Liu, Shi Yu Guo, Jing Jun Zhao, Chun Fang Wang, Lan Yan, Guo Tong Xu, Yuan Ying Jiang, Mao Mao An
Candida glabrata is the second most common pathogen of severe candidiasis in immunocompromised hosts, following C. albicans. Although C. glabrata and C. albicans belong to the same genus, they are phylogenetically distinct. C-type lectin receptors (CLRs), acting as pattern-recognition receptors (PRRs), play critical roles in host defense against C. albicans infections. However, our understanding of the specific roles of CLRs in host defense against C. glabrata is limited. Here, we explored the potential roles of the C-type lectins Dectin-1 and Dectin-2 in host defense against C...
June 28, 2017: Virulence
https://www.readbyqxmd.com/read/28650701/prevalence-of-acinetobacter-baumannii-strains-expressing-the-type-6-secretion-system-in-patients-with-bacteremia
#14
Guillermo D Repizo
No abstract text is available yet for this article.
June 26, 2017: Virulence
https://www.readbyqxmd.com/read/28644759/virulence-profile-mark-thomas
#15
Mark Thomas
No abstract text is available yet for this article.
June 23, 2017: Virulence
https://www.readbyqxmd.com/read/28641041/virulence-regulation-during-late-infection-by-a-fish-pathogen-sense-and-sensibility-of-bacteria-may-lead-to-novel-vaccine-development-strategy
#16
https://www.readbyqxmd.com/read/28636422/usurping-bacterial-virulence-factors-as-self-delivery-vehicles-for-therapeutic-use
#17
Rachel M Olson, Deborah M Anderson
No abstract text is available yet for this article.
June 21, 2017: Virulence
https://www.readbyqxmd.com/read/28632426/what-is-behind-the-epidemiological-difference-between-community-acquired-and-health-care-associated-methicillin-resistant-staphylococcus-aureus
#18
https://www.readbyqxmd.com/read/28622093/suppressive-effect-of-dengue-virus-envelope-protein-domain-iii-on-megakaryopoiesis
#19
Guan-Ling Lin, Hsin-Hou Chang, Te-Sheng Lien, Po-Kong Chen, Hao Chan, Mei-Tzu Su, Chi-Yuan Liao, Der-Shan Sun
Dengue virus (DENV) infection can cause severe, life-threatening events, and no specific treatments of DENV infection are currently approved. Although thrombocytopenia is frequently observed in dengue patients, its pathogenesis is still not fully understood. Previous studies have suggested that DENV-induced thrombocytopenia occurs through viral-replication-mediated megakaryopoiesis inhibition in the bone marrow; however, the exact mechanism for megakaryopoiesis suppression remains elusive. In this study, a reductionist approach was applied, in which C57B/6J mice were inoculated with recombinant DENV-envelope protein domain III (DENV-EIII) instead of the full viral particle...
June 16, 2017: Virulence
https://www.readbyqxmd.com/read/28622084/the-streptococcus-suis-factor-h-binding-protein-a-key-to-unlocking-the-blood-brain-barrier-and-access-the-central-nervous-system
#20
Jean-Philippe Auger, Marcelo Gottschalk
No abstract text is available yet for this article.
June 16, 2017: Virulence
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