journal
MENU ▼
Read by QxMD icon Read
search

Virulence

journal
https://www.readbyqxmd.com/read/28644759/virulence-profile-mark-thomas
#1
Mark Thomas
No abstract text is available yet for this article.
June 23, 2017: Virulence
https://www.readbyqxmd.com/read/28641041/virulence-regulation-during-late-infection-by-a-fish-pathogen-sense-and-sensibility-of-bacteria-may-lead-to-novel-vaccine-development-strategy
#2
https://www.readbyqxmd.com/read/28636422/usurping-bacterial-virulence-factors-as-self-delivery-vehicles-for-therapeutic-use
#3
Rachel M Olson, Deborah M Anderson
No abstract text is available yet for this article.
June 21, 2017: Virulence
https://www.readbyqxmd.com/read/28632426/what-is-behind-the-epidemiological-difference-between-community-acquired-and-health-care-associated-methicillin-resistant-staphylococcus-aureus
#4
https://www.readbyqxmd.com/read/28622093/suppressive-effect-of-dengue-virus-envelope-protein-domain-iii-on-megakaryopoiesis
#5
Guan-Ling Lin, Hsin-Hou Chang, Te-Sheng Lien, Po-Kong Chen, Hao Chan, Mei-Tzu Su, Chi-Yuan Liao, Der-Shan Sun
Dengue virus (DENV) infection can cause severe, life-threatening events, and no specific treatments for DENV infection are currently approved. Although thrombocytopenia is frequently observed in dengue patients, its pathogenesis is still not fully understood. Previous studies have suggested that DENV-induced thrombocytopenia occurs through viral-replication-mediated megakaryopoiesis inhibition in the bone marrow; however, the exact mechanism for megakaryopoiesis suppression remains elusive. In this study, a reductionist approach was applied, in which C57B/6J mice were inoculated with recombinant DENV-envelope protein domain III (DENV-EIII) instead of the full viral particle...
June 16, 2017: Virulence
https://www.readbyqxmd.com/read/28622084/the-streptococcus-suis-factor-h-binding-protein-a-key-to-unlocking-the-blood-brain-barrier-and-access-the-central-nervous-system
#6
Jean-Philippe Auger, Marcelo Gottschalk
No abstract text is available yet for this article.
June 16, 2017: Virulence
https://www.readbyqxmd.com/read/28614673/pseudogymnoascus-destructans-transcriptome-changes-during-white-nose-syndrome-infections
#7
Sophia M Reeder, Jonathan M Palmer, Jenni M Prokkola, Thomas M Lilley, DeeAnn M Reeder, Kenneth A Field
White nose syndrome (WNS) is caused by the psychrophilic fungus Pseudogymnoascus destructans that can grow in the environment saprotrophically or parasitically by infecting hibernating bats. Infections are pathological in many species of North American bats, disrupting hibernation and causing mortality. To determine what fungal pathways are involved in infection of living tissue, we examined fungal gene expression using RNA-Seq. We compared P. destructans gene expression when grown in culture to that during infection of a North American bat species, Myotis lucifugus, that shows high WNS mortality...
June 14, 2017: Virulence
https://www.readbyqxmd.com/read/28605283/interferon-%C3%AE-controls-non-tuberculous-mycobacterial-infection-in-mice
#8
Mohd-Nor Norazmi
No abstract text is available yet for this article.
June 12, 2017: Virulence
https://www.readbyqxmd.com/read/28605238/mucin-1-protects-against-severe-streptococcus-pneumoniae-infection
#9
Poshmaal Dhar, Garrett Z Ng, Eileen M Dunne, Philip Sutton
Streptococcus pneumoniae is a bacterial pathogen that commonly resides in the human nasopharynx, typically without causing any disease. However, in some cases these bacteria migrate from the nasopharynx to other sites of the body such as the lungs and bloodstream causing pneumonia and sepsis, respectively. This study used a mouse model of infection to investigate the potential role of Mucin 1 (MUC1), a cell membrane-associated glycoprotein known for playing a key barrier role at mucosal surfaces, in regulating this process...
June 12, 2017: Virulence
https://www.readbyqxmd.com/read/28598246/the-effect-of-isaba1-mediated-aden-gene-disruption-on-acinetobacter-baumannii-pathogenesis
#10
Man Hwan Oh, Chul Hee Choi, Je Chul Lee
No abstract text is available yet for this article.
June 9, 2017: Virulence
https://www.readbyqxmd.com/read/28594271/treatment-of-cyclosporin-a-retains-host-defense-against-invasive-pulmonary-aspergillosis-in-a-non-immunosuppressive-murine-model-by-preserving-the-myeloid-cell-population
#11
Sarah Sze Wah Wong, Orhan Rasid, Paris Laskaris, Arnaud Fekkar, Jean-Marc Cavaillon, William J Steinbach, Oumaima Ibrahim-Granet
Cyclosporin A (CsA) is widely used as an immunosuppressive agent for organ transplant recipients. CsA inhibits calcineurin, which is highly conserved in mammals and fungi, and thus affects both types of organism. In mammals, the immunosuppressive effect of CsA is via hampering T cell activation. In fungi, the growth inhibitory effect of CsA is via interference with hyphal growth. The aim of this study was to determine whether CsA renders mice susceptible to invasive pulmonary aspergillosis (IPA) and whether it can protect immunosuppressed mice from infection...
June 8, 2017: Virulence
https://www.readbyqxmd.com/read/28594267/a-plant-pathogenic-bacterium-exploits-the-tricarboxylic-acid-cycle-metabolic-pathway-of-its-insect-vector
#12
Nabil Killiny, Yasser Nehela, Faraj Hijaz, Christopher I Vincent
Huanglongbing in citrus is caused by a phloem-limited, uncultivable, gram-negative α-proteobacterium, Candidatus Liberibacter asiaticus (CLas). CLas is transmitted by the phloem-sucking insect, Diaphorina citri (Hemiptera: Liviidae), in a persistent, circulative, and propagative manner. In this study, we investigated the metabolomic and respiration rates changes in D. citri upon infection with CLas using gas chromatography-mass spectrometry (GC-MS) and gas exchange analysis. The level of glycine, L-serine, L-threonine, and gamma-amino butyric acid were higher in CLas-infected D...
June 8, 2017: Virulence
https://www.readbyqxmd.com/read/28570123/functional-insights-into-the-magnaporthe-oryzae-class-ii-myosin
#13
Thabiso E Motaung, Toi J Tsilo
No abstract text is available yet for this article.
June 1, 2017: Virulence
https://www.readbyqxmd.com/read/28521626/experimental-evolution-of-resistance-against-bacillus-thuringiensis-in-the-insect-model-host-galleria-mellonella-results-in-epigenetic-modifications
#14
Krishnendu Mukherjee, Ekaterina Grizanova, Ekaterina Chertkova, Ruediger Lehmann, Ivan Dubovskiy, Andreas Vilcinskas
Epigenetic mechanisms have been proposed to translate environmental stimuli into heritable transgenerational phenotypic variations that can significantly influence natural selection. An intriguing example is exposure to pathogens, which imposes selection for host resistance. To test this hypothesis, we used larvae of the greater wax moth Galleria mellonella as model host to experimentally select for resistance to Bacillus thuringiensis (Bt), the most widely used bacterial agent for the biological control of pest insects...
May 19, 2017: Virulence
https://www.readbyqxmd.com/read/28498729/the-distinct-function-of-tep2-and-tep6-in-the-immune-defense-of-drosophila-melanogaster-against-the-pathogen-photorhabdus
#15
Upasana Shokal, Hannah Kopydlowski, Ioannis Eleftherianos
Previous and recent investigations on the innate immune response of Drosophila have identified certain mechanisms that promote pathogen elimination. However, the function of Thioester-containing proteins (TEPs) in the fly still remains elusive. Recently we have shown the contribution of TEP4 in the antibacterial immune defense of Drosophila against non-pathogenic E. coli, and the pathogens Photorhabdus luminescens and P. asymbiotica. Here we studied the function of Tep genes in both humoral and cellular immunity upon E...
May 12, 2017: Virulence
https://www.readbyqxmd.com/read/28489963/the-aspergillus-fumigatus-farnesyltransferase-%C3%AE-subunit-rama-mediates-growth-virulence-and-antifungal-susceptibility
#16
Tiffany S Norton, Qusai Al Abdallah, Amy M Hill, Rachel V Lovingood, Jarrod R Fortwendel
Post-translational prenylation mechanisms, including farnesylation and geranylgeranylation, mediate both subcellular localization and protein-protein interaction in eukaryotes. The prenyltransferase complex is an αβ heterodimer in which the essential α-subunit is common to both the farnesyltransferase and the geranylgeranyltransferase type-I enzymes. The β-subunit is unique to each enzyme. Farnesyltransferase activity is an important mediator of protein localization and subsequent signaling for multiple proteins, including Ras GTPases...
May 10, 2017: Virulence
https://www.readbyqxmd.com/read/28489958/zinc-metalloproteinase-zmpc-suppresses-experimental-pneumococcal-meningitis-by-inhibiting-bacterial-invasion-of-central-nervous-systems
#17
Masaya Yamaguchi, Masanobu Nakata, Ryuichi Sumioka, Yujiro Hirose, Satoshi Wada, Yukihiro Akeda, Tomoko Sumitomo, Shigetada Kawabata
Streptococcus pneumoniae is a leading cause of bacterial meningitis. Here, we investigated whether pneumococcal paralogous zinc metalloproteases contribute to meningitis onset. Findings of codon-based phylogenetic analyses indicated 3 major clusters in the Zmp family; ZmpA, ZmpC, and ZmpB, with ZmpD as a subgroup. In vitro invasion assays of human brain microvascular endothelial cells (hBMECs) showed that deletion of the zmpC gene in S. pneumoniae strain TIGR4 significantly increased bacterial invasion into hBMECs, whereas deletion of either zmpA or zmpB had no effect...
May 10, 2017: Virulence
https://www.readbyqxmd.com/read/28489957/unravelling-pathogenetic-mechanisms-of-epidemic-lineages
#18
Oddvar Oppegaard
No abstract text is available yet for this article.
May 10, 2017: Virulence
https://www.readbyqxmd.com/read/28481721/s-oralis-activates-the-efg1-filamentation-pathway-in-c-albicans-to-promote-cross-kingdom-interactions-and-mucosal-biofilms
#19
Hongbin Xu, Takanori Sobue, Martinna Bertolini, Angela Thompson, Margaret Vickerman, Clarissa J Nobile, Anna Dongari-Bagtzoglou
Candida albicans and Streptococcus oralis are ubiquitous oral commensal organisms. Under host-permissive conditions these organisms can form hypervirulent mucosal biofilms. C. albicans biofilm formation is controlled by 6 master transcriptional regulators: Bcr1, Brg1, Efg1, Tec1, Ndt80, and Rob1. The objective of this work was to test whether any of these regulators play a role in cross-kingdom interactions between C. albicans and S. oralis in oral mucosal biofilms, and identify downstream target gene(s) that promote these interactions...
May 8, 2017: Virulence
https://www.readbyqxmd.com/read/28481716/dna-vaccination-resurfaces-in-the-struggle-against-melioidosis
#20
Sophie A Aschenbroich
No abstract text is available yet for this article.
May 8, 2017: Virulence
journal
journal
43028
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"