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Nuclear Medicine and Molecular Imaging

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https://www.readbyqxmd.com/read/27540434/false-positive-radioactive-iodine-uptake-mimicking-miliary-lung-metastases-in-a-patient-affected-by-papillary-thyroid-cancer-and-iga-deficiency
#1
Andrew Paul Demidowich, Amartya Kundu, James C Reynolds, Francesco S Celi
A 42-year-old female with immunoglobulin A deficiency and recurrent sinopulmonary infections underwent thyroidectomy for papillary thyroid cancer (PTC). Follow-up (123)I scintigraphy demonstrated diffuse pulmonary uptake, suggesting metastatic disease. However, subsequent pathologic, biochemical and radiographic testing proved that she was in fact disease free, and the initial (123)I pulmonary uptake was identified as a false positive. Inflammatory conditions may rarely cause iodine uptake in non-thyroidal tissues due to local retention, organification, and/or immunologic utilization...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540433/vertebral-uptake-of-tc-99m-macroaggregated-albumin-maa-with-spect-ct-occurring-in-superior-vena-cava-obstruction
#2
Shawn Karls, Hani Hassoun, Vilma Derbekyan
A 67-year-old male presented with dyspnea for which lung scintigraphy was ordered to rule out pulmonary embolus. Planar images demonstrated abnormal midline uptake of Tc-99m macroaggregated albumin, which SPECT/CT localized to several thoracic vertebrae. Thoracic vertebral uptake on perfusion lung scintigraphy was previously described on planar imaging. Radionuclide venography and contrast-enhanced CT subsequently demonstrated superior vena cava (SVC) obstruction with collateralization through the azygous/hemiazygous system and vertebral venous plexus...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540432/role-of-18-f-fdg-pet-ct-in-monitoring-the-cyclophosphamide-induced-pulmonary-toxicity-in-patients-with-breast-cancer-2-case-reports
#3
Sameer Kamalakar Taywade, Rakesh Kumar, Sainath Bhethanabhotla, Chandrasekhar Bal
Drug induced pulmonary toxicity is not uncommon with the use of various chemotherapeutic agents. Cyclophosphamide is a widely used chemotherapeutic drug in the treatment of breast cancer. Although rare, lung toxicity has been reported with cyclophosphamide use. Detection of bleomycin induced pulmonary toxicity and pattern of (18)F-fluorodeoxyglucose ((18)F-FDG) uptake in lungs on fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) has been elicited in literature in relation to lymphoma...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540431/brain-18-f-fdg-18-f-florbetaben-pet-ct-123-i-fp-cit-spect-and-cardiac-123-i-mibg-imaging-for-diagnosis-of-a-cerebral-type-of-lewy-body-disease
#4
Axel Van Der Gucht, Laurent Cleret de Langavant, Ophélie Bélissant, Corentin Rabu, Anne-Ségolène Cottereau, Eva Evangelista, Julia Chalaye, Sophie Bonnot-Lours, Gilles Fénelon, Emmanuel Itti
A 67-year-old man was referred for fluctuating neuropsychiatric symptoms, featuring depression, delirious episodes, recurrent visual hallucinations and catatonic syndrome associated with cognitive decline. No parkinsonism was found clinically even under neuroleptic treatment. (18)F-FDG PET/CT showed hypometabolism in the posterior associative cortex including the occipital cortex, suggesting Lewy body dementia, but (123)I-FP-CIT SPECT was normal and cardiac (123)I-MIBG imaging showed no signs of sympathetic denervation...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540430/cowden-syndrome-detected-by-fdg-pet-ct-in-an-endometrial-cancer-patient
#5
Yun Hee Kang, Hye Kyung Lee, Geon Park
Cowden syndrome (CS) is a rare autosomal dominant disorder characterized by multiple hamartomas in various tissues and cancers (breast, thyroid, and endometrium). We report CS of the esophagus and gastrointestinal tract that was incidentally detected by positron emission tomography/computed tomography (PET/CT) at postoperative surveillance in an endometrial cancer patient. PET/CT showed mildly increased FDG uptake along the entire esophagus and stomach. Upper GI endoscopy and histologic examination revealed glycogenic acanthosis of the esophagus and several hundred gastric polyps...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540429/the-relationship-between-estrogen-receptor-progesterone-receptor-and-human-epidermal-growth-factor-receptor-2-expression-of-breast-cancer-and-the-retention-index-in-dual-phase-18-f-fdg-pet-ct
#6
Hansol Moon, Woo Chul Noh, Hyun-Ah Kim, Eun-Kyu Kim, Ko Woon Park, Seung Sook Lee, Joon Ho Choi, Kyung Woo Han, Byung Hyun Byun, Ilhan Lim, Byung Il Kim, Chang Woon Choi, Sang Moo Lim
PURPOSE: This study investigates the correlation of retention index (RI) using the dual phase FDG PET/CT scan with the breast cancer biomarkers. METHODS: A total of 55 patients with breast cancer underwent dual phase FDG PET/CT scans (60 and 120 min after FDG injection) before treatment. SUVmax and SUVmean of the primary breast tumors were measured, then the percent change of SUVmax and SUVmean between the two scans were calculated, and denoted as RImax and RImean, respectively...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540428/factors-associated-with-18-f-fluorodeoxyglucose-uptake-in-t1-and-t2-invasive-ductal-carcinoma-of-the-breast
#7
So Jung Kim, Seong-Jang Kim, In Joo Kim, Kyoungjune Pak, Bum Soo Kim, Seunghyeon Shin
PURPOSE: The objective of this study was to investigate the relationship between diversity of (18)F-fluorodeoxyglucose ((18)F-FDG) uptake of primary tumor in positron emission tomography (PET) and various clinicopathologic factors in breast cancer of same pathologic T1, T2 stage. METHODS: A total of 258 patients with invasive ductal breast cancer were enrolled in this study. All patients underwent (18)F-FDG PET-CT before surgery. Patients were divided into two groups according to tumor size based on the pathologic T stage, and maximum standardized uptake value (SUVmax) of 2...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540427/conspicuity-of-fdg-avid-osseous-lesions-on-pet-mri-versus-pet-ct-a-quantitative-and-visual-analysis
#8
Tyler J Fraum, Kathryn J Fowler, Jonathan McConathy
BACKGROUND: Because standard MRI-based attenuation correction (AC) does not account for the attenuation of photons by cortical bone, PET/MRI may have reduced sensitivity for FDG-avid focal bone lesions (FFBLs). This study evaluates whether MRI-based AC compromises detection of FFBLs, by comparing their conspicuity both quantitatively and qualitatively on PET/MRI versus PET/CT. METHODS: One hundred ninety general oncology patients underwent whole-body PET/CT followed by whole-body PET/MRI, utilizing the same FDG dose...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540426/comparison-of-the-performances-of-18-f-fp-cit-brain-pet-mr-and-simultaneous-pet-ct-a-preliminary-study
#9
SangDon Kwon, KyungAh Chun, EunJung Kong, IhnHo Cho
PURPOSE: (18)F-FP-CIT [(18)F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane] has been well established and used for the differential diagnosis of atypical parkinsonian disorders. Recently, combined positron emission tomography (PET)/magnetic resonance (MR) was proposed as a viable alternative to PET/computed tomography (CT). The aim of this study was to compare the performances of conventional (18)F-FP-CIT brain PET/CT and simultaneous PET/MR by visual inspection and quantitative analysis...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540425/open-mouth-bone-scintigraphy-is-better-than-closed-mouth-bone-scintigraphy-in-the-diagnosis-of-temporomandibular-osteoarthritis
#10
Ki Seong Park, Ho-Chun Song, Sang-Geon Cho, Sae-Ryung Kang, Jahae Kim, Haeng Man Jun, Minchul Song, Geum-Cheol Jeong, Hee Jeong Park, Seong Young Kwon, Jung-Joon Min, Henry Hee-Seung Bom
PURPOSE: Closed-mouth bone scintigraphy (CM scan) and closed-mouth single-photon emission computed tomography (CM SPECT) are used for conventional evaluation of osteoarthritis of the temporomandibular joint (TMJ). However, the adequacy of open-mouth bone scintigraphy (OM scan) has not yet been evaluated. Therefore, the purpose of this study was to compare the diagnostic performance of CM scan, CM SPECT, and OM scan. METHODS: Thirty-six patients with suspicion of an abnormality of the TMJ and who underwent a (99m)Tc-HDP CM scan, CM SPECT, and an OM scan were enrolled...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540424/pixelized-measurement-of-99m-tc-hdp-micro-particles-formed-in-gamma-correction-phantom-pinhole-scan-a-reference-study
#11
Joo-Young Jung, Gi Jeong Cheon, Yun-Sang Lee, Seunggyun Ha, Mi-Hye Chae, Yong-An Chung, Do Kyun Yoon, Yong-Whee Bahk
PURPOSE: Currently, traumatic bone diseases are diagnosed by assessing the micro (99m)Tc-hydroxymethylene diphosphonate (HDP) uptake in injured trabeculae with ongoing osteoneogenesis demonstrated by gamma correction pinhole scan (GCPS). However, the mathematic size quantification of micro-uptake is not yet available. We designed and performed this phantom-based study to set up an in-vitro model of the mathematical calculation of micro-uptake by the pixelized measurement. METHODS: The micro (99m)Tc-HDP deposits used in this study were spontaneously formed both in a large standard flood and small house-made dish phantoms...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540423/recent-advances-in-nuclear-cardiology
#12
REVIEW
Won Woo Lee
Nuclear cardiology is one of the major fields of nuclear medicine practice. Myocardial perfusion studies using single-photon emission computed tomography (SPECT) have played a crucial role in the management of coronary artery diseases. Positron emission tomography (PET) has also been considered an important tool for the assessment of myocardial viability and perfusion. However, the recent development of computed tomography (CT)/magnetic resonance imaging (MRI) technologies and growing concerns about the radiation exposure of patients remain serious challenges for nuclear cardiology...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540422/radiolabeled-phosphonium-salts-as-mitochondrial-voltage-sensors-for-positron-emission-tomography-myocardial-imaging-agents
#13
REVIEW
Dong-Yeon Kim, Jung-Joon Min
Despite substantial advances in the diagnosis of cardiovascular disease, (18)F-labeled positron emission tomography (PET) radiopharmaceuticals remain necessary to diagnose heart disease because clinical use of current PET tracers is limited by their short half-life. Lipophilic cations such as phosphonium salts penetrate the mitochondrial membranes and accumulate in mitochondria of cardiomyocytes in response to negative inner-transmembrane potentials. Radiolabeled tetraphenylphosphonium cation derivatives have been developed as myocardial imaging agents for PET...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540421/use-of-nuclear-medicine-technology-for-clinical-molecular-imaging-a-message-from-the-associate-editor
#14
Byeong-Cheol Ahn
No abstract text is available yet for this article.
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275374/detection-of-synchronous-parathyroid-adenoma-and-breast-cancer-with-18-f-fluorocholine-pet-ct
#15
Wessel McM Vorselaars, Wouter P Kluijfhout, Menno R Vriens, Carmen C van der Pol, Inne Hm Borel Rinkes, Gerlof D Valk, Bart de Keizer
No abstract text is available yet for this article.
June 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275373/inferior-vena-cava-filter-thrombus-a-possible-cause-of-an-unanticipated-finding-of-99m-tc-labeled-red-blood-cell-scintigraphy
#16
Heesung Song, Joon Hyouk Choi, Young Suk Kim
(99m)Tc-labeled red blood cell scintigraphy, a sensitive and specific diagnostic test, is useful for patients suspected of suffering from active gastrointestinal bleeding. This study follows a case of a patient who was suspected of gastrointestinal bleeding after an inferior vena cava filter was inserted due to a deep vein thrombosis of the femoral vein. To evaluate an exact focus of bleeding, (99m)Tc-labeled red blood cell scintigraphy was executed. Herein, an unanticipated finding of (99m)Tc-labeled red blood cell scintigraphy probably due to a thrombus on the inferior vena cava filter is reported...
June 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275372/primary-rectal-adenocarcinoma-metastasizing-to-bilateral-breasts-a-rare-case-demonstrated-by-18-%C3%A2-f-fdg-pet-ct
#17
Ramya Soundararajan, Saurabh Arora, Chandan Jyoti Das, Maitrayee Roy, Rakesh Kumar, Chandrasekhar Bal
No abstract text is available yet for this article.
June 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275371/lymphoscintigraphy-spect-ct-instrumental-navigator-in-repair-of-thoracic-duct-injury
#18
Aini AbAziz, Syahrir M Yusop, Mohd Fadzil Mohd Tahir, Yew Cheng Lim, Hans-Jurgen Gallowitsch
No abstract text is available yet for this article.
June 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275370/18f-fdg-pet-ct-for-detecting-sarcoma-of-the-aorta-in-a-patient-with-takayasu-arteritis
#19
Tomoko Takahashi, Naoto Watanabe, Minoru Wakasa, Kouji Kajinami, Hisao Tonami
No abstract text is available yet for this article.
June 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27275369/intramedullary-spinal-cord-metastasis-from-breast-cancer-mimicking-delayed-radiation-myelopathy-detection-with-18-f-fdg-pet-ct
#20
Terufumi Kawamoto, Toshinari Yamashita, Satoshi Kaito, Yoshiharu Miura
No abstract text is available yet for this article.
June 2016: Nuclear Medicine and Molecular Imaging
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