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Journal of Neurogastroenterology and Motility

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https://www.readbyqxmd.com/read/30180307/quantitative-analysis-of-distribution-of-the-gastrointestinal-tract-eosinophils-in-childhood-functional-abdominal-pain-disorders
#1
Eun Hye Lee, Hye Ran Yang, Hye Seung Lee
Background/Aims: Although functional abdominal pain disorders (FAPDs) are common in children, the accurate pathogenesis of FAPDs is not known yet. Micro-inflammation, particularly tissue eosinophilia of gastrointestinal (GI) tract, has been suggested as the pathophysiology observed in several GI disorders. We aimed to evaluate eosinophilic infiltration throughout the entire GI tract in children with FAPDs, compared to those with inflammatory bowel diseases (IBD) and to normal reference values...
September 3, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30153722/cultural-factors-influencing-functional-gastrointestinal-disorders-in-the-east
#2
Kee-Huat Chuah, Sanjiv Mahadeva
Culture forms an integral aspect of environmental factors which influences disease presentation and clinical outcomes in functional gastrointestinal disorders (FGIDs). In this review, the role of culture in FGIDs in the East is briefly explored with regards to symptom presentation and diagnostic issues, lifestyle and cultural habits, epidemiology, and healthcare seeking behavior. In both functional dyspepsia and irritable bowel syndrome, symptom presentation and disease sub-typing in Asians are known to differ from their Western counterparts, possibly relating to cultural dietary practices and from cultural perception of symptoms...
August 29, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30153721/aloe-vera-is-effective-and-safe-in-short-term-treatment-of-irritable-bowel-syndrome-a-systematic-review-and-meta-analysis
#3
Seung Wook Hong, Jaeyoung Chun, Sunmin Park, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
Background/Aims: To evaluate the efficacy and safety of Aloe vera (AV) in patients with irritable bowel syndrome (IBS). Methods: We searched the MEDLINE, EMBASE, and Cochrane databases for studies dated between 1st January 1960 and 30th December 2017. Eligible randomized controlled trials (RCTs) compared AV to placebo in patients with IBS. The primary outcome was standardized mean difference of the change in severity of IBS symptoms as measured by patient-rated scales...
August 29, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30122029/improving-high-resolution-impedance-manometry-using-novel-viscous-and-super-viscous-substrates-in-the-supine-and-upright-positions-a-pilot-study
#4
Uni Wong, Erik B Person, Donald O Castell, Erik von Rosenvinge, Jean-Pierre Raufman, Guofeng Xie
Background/Aims: Swallows with viscous or solid boluses in different body positions alter esophageal manometry patterns. Limitations of previous studies include lack of standardized viscous substrates and the need for chewing prior to swallowing solid boluses. We hypothesize that high-resolution impedance manometry (HRiM) using standardized viscous and super-viscous swallows in supine and upright positions improves sensitivity for detecting esophageal motility abnormalities when compared with traditional saline swallows...
August 18, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30114898/the-effect-of-trimebutine-on-the-overlap-syndrome-model-of-guinea-pigs
#5
Zahid Hussain, Da Hyun Jung, Young Ju Lee, Hyojin Park
Background/Aims: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) disorders and these patients frequently overlap. Trimebutine has been known to be effective in controlling FD co-existing diarrhea-dominant IBS, however its effect on overlap syndrome (OS) patients has not been reported. Therefore, we investigated the effect of trimebutine on the model of OS in guinea pigs. Methods: Male guinea pigs were used to evaluate the effects of trimebutine in corticotropin-releasing factor (CRF) induced OS model...
August 16, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30041284/understanding-neurogastroenterology-from-neuroimaging-perspective-a-comprehensive-review-of-functional-and-structural-brain-imaging-in-functional-gastrointestinal-disorders
#6
REVIEW
Michiko Kano, Patrick Dupont, Qasim Aziz, Shin Fukudo
This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses in regions related to sensory processing of the homeostatic condition of the gut (homeostatic afferent) and responses to salience stimuli (salience network), as well as increased and decreased brain activity in the emotional response areas and reduced activation in areas associated with the top-down modulation of visceral afferent signals...
July 24, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29955019/to-understand-the-modulatory-effect-of-probiotics-on-irritable-bowel-syndrome
#7
LETTER
Anlong Yuan, Peng Li, Li Wang, Bibo Zhong, Bin Bai, Xiaoyu Huang, Jiguang Kou
No abstract text is available yet for this article.
June 29, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29938463/prevalence-and-risk-factors-of-functional-dyspepsia-in-health-check-up-population-a-nationwide-multicenter-prospective-study
#8
Sung Eun Kim, Nayoung Kim, Ju Yup Lee, Kyung Sik Park, Jeong Eun Shin, Kwangwoo Nam, Hyeon Ju Kim, Hyun Joo Song, Young-Eun Joo, Dae-Seong Myung, Ji-Hyun Seo, Hyun Jin Jo, Seon Mie Kim, Seon Hee Lim, Hyun Jin Kim, Gwang Ho Baik, Sang Hyeon Choi, Suck Chei Choi
Background/Aims: Functional dyspepsia (FD) is one of the most common gastrointestinal disorders, and FD imposes social and economic burden worldwide. The aim of this study was to identify the prevalence and risk factors of FD in health check-up population in tertiary centers in Korea. Methods: A nationwide multicenter prospective study was performed at 9 tertiary healthcare centers in Korea between September 2016 and June 2017. A total of 2525 subjects were investigated based on endoscopic findings and questionnaires with Rome III criteria, and Helicobacter pylori serology (IgG)...
June 23, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969864/factors-determining-the-inter-observer-variability-and-diagnostic-accuracy-of-high-resolution-manometry-for-esophageal-motility-disorders
#9
Ji Hyun Kim, Sung Eun Kim, Yu Kyung Cho, Chul-Hyun Lim, Moo In Park, Jin Won Hwang, Jae-Sik Jang, Minkyung Oh
The figure 6 should have been presented as follows.
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969863/rumination-syndrome-unknown-pathology-easy-to-diagnose-with-high-resolution-impedance-manometry
#10
LETTER
Esperanza Martos Vizcaino, Fernando Canga Rodriguez-Valcárcel, Constanza Ciriza de Los Ríos
No abstract text is available yet for this article.
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969862/response-to-treatment-of-helicobacter-pylori-associated-dyspepsia-eradication-of-helicobacter-pylori-or-correction-of-gastric-or-intestinal-dysbiosis
#11
LETTER
Philip Abraham, Verima Pereira
No abstract text is available yet for this article.
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969861/relation-of-enteric-%C3%AE-synuclein-to-gastrointestinal-dysfunction-in-patients-with-parkinson-s-disease-and-in-neurologically-intact-subjects
#12
Hyo Jeong Lee, Kee Wook Jung, Sun Ju Chung, Seung-Mo Hong, Juyeon Kim, Jeong Hoon Lee, Sung Wook Hwang, Ho-Sung Ryu, Mi Jung Kim, Ho-Su Lee, Myeongsook Seo, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Jaewon Choe, Hwoon-Yong Jung, Suk-Kyun Yang, Seung-Jae Myung
Background/Aims: α-Synucleinopathy in the brain is the neuropathological hallmark of Parkinson's disease (PD). However, the functional impact of α-synucleinopathy in the enteric nervous system remains unknown. We aim to evaluate the association between gastrointestinal (GI) dysfunction and α-synuclein (αSYN) pathology in the stomach and colon of PD patients and controls, as well as to investigate the association between the αSYN pathology in GI tract and future PD risk. Methods: A total of 35 PD patients and 52 neurologically intact subjects were enrolled in this study...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969860/effects-of-the-administration-of-probiotics-on-fecal-microbiota-diversity-and-composition-in-healthy-individuals
#13
Choong-Kyun Noh, Bong Sun Kim, Gana Hong, Jae Youn Cheong, Kwang Jae Lee
Background/Aims: Probiotics are expected to modify the composition of gut microbiota. We aimed to investigate the changes in the composition and diversity of gut microbiota by the administration of probiotics in healthy individuals. Methods: Twelve healthy volunteers with age range of 30-42 years provided baseline fecal samples. Subsequently, they took commercially available probiotic capsules (a mixture for Bifidobacterium , Lactobacillus , and Enterococcus ) for 4 weeks...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969859/200-ml-rapid-drink-challenge-during-high-resolution-manometry-best-predicts-objective-esophagogastric-junction-obstruction-and-correlates-with-symptom-severity
#14
Philip Woodland, Shirley Gabieta-Sonmez, Julieta Arguero, Joanne Ooi, Kenichiro Nakagawa, Esteban Glasinovic, Etsuro Yazaki, Daniel Sifrim
Background/Aims: Single swallow integrated relaxation pressure (IRP) on high-resolution manometry (HRM) does not always accurately predict esophagogastric outflow obstruction on timed barium esophagogram (TBE). Furthermore, neither single swallow IRP or TBE is reliable in predicting symptoms, particularly after treatment with dilatation or myotomy. A 200 mL rapid drink challenge (RDC) has been proposed as an adjunctive test during HRM. This serves as a "stress-test" to the esophagogastric junction, and may yield clinically useful parameters...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969858/esophagography-in-patients-with-esophageal-achalasia-diagnosed-with-high-resolution-esophageal-manometry
#15
Takahisa Yamasaki, Toshihiko Tomita, Sumire Mori, Mayu Takimoto, Akio Tamura, Ken Hara, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
Background/Aims: High-resolution esophageal manometry (HREM) is considered to be the gold standard for the diagnosis of achalasia. However, the Japan Esophageal Society recommends that esophagography is also accurate in either diagnosing or excluding the disorder. Accordingly, we compared the efficacy of esophagography and HREM in diagnosing achalasia patients with upper gastrointestinal symptoms. Methods: HREM was performed in 126 patients with dysphagia. The final diagnosis of achalasia was done using HREM...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969857/abnormal-bolus-reflux-is-associated-with-poor-pulmonary-outcome-in-patients-with-idiopathic-pulmonary-fibrosis
#16
Lawrence F Borges, Vikrant Jagadeesan, Hilary Goldberg, Sravanya Gavini, Wai-Kit Lo, Robert Burakoff, Natan Feldman, Walter W Chan
Background/Aims: Gastroesophageal reflux (GER) is postulated to play a role in idiopathic pulmonary fibrosis (IPF). However, the value of objective GER measures in predicting IPF disease progression is unclear. We aim to evaluate the association between objective GER measures on multichannel intraluminal impedance and pH (MII-pH) testing and development of poor pulmonary outcomes within 1 year in prelung transplant IPF patients. Methods: This was a retrospective cohort study of adults with IPF who underwent pre-lung transplant evaluation with MII-pH off proton pump inhibitors (PPI) at a tertiary care center from June 2008 to November 2015...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969856/chronic-cough-is-associated-with-long-breaks-in-esophageal-peristaltic-integrity-on-high-resolution-manometry
#17
Michael C Bennett, Amit Patel, Nitin Sainani, Dan Wang, Gregory S Sayuk, C Prakash Gyawali
Background/Aims: Breaks in the peristaltic contour on esophageal high-resolution manometry (HRM) may be associated with bolus retention in the esophagus. We evaluated the relationship between peristaltic breaks and esophageal symptoms, reflux exposure, and symptom outcomes in a prospective patient cohort. Methods: Two hundred and eighteen patients (53.2 ± 0.9 years, 68.3% female) undergoing both pH-impedance testing and HRM over a 5-year period were prospectively evaluated...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969855/role-of-gut-microbiota-gut-hormone-axis-in-the-pathophysiology-of-functional-gastrointestinal-disorders
#18
REVIEW
Hirokazu Fukui, Xin Xu, Hiroto Miwa
Gut microbiota exert a pivotal influence on various functions including gastrointestinal (GI) motility, metabolism, nutrition, immunity, and the neuroendocrine system in the host. These effects are mediated by not only short-chain fatty acids produced by microbiota but also gut hormones and inflammatory signaling by enteroendocrine and immune cells under the influence of the microbiota. GI motility is orchestrated by the enteric nervous system and hormonal networks, and disturbance of GI motility plays an important role in the pathophysiology of functional gastrointestinal disorders (FGIDs)...
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969854/is-high-resolution-anorectal-pressure-topography-more-useful-than-wave-manometry-in-dyssynergic-defecation
#19
EDITORIAL
Tae Hee Lee
No abstract text is available yet for this article.
July 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29969853/which-provocation-test-will-be-added-to-routine-high-resolution-manometry-protocol-in-unexplained-dysphagia
#20
EDITORIAL
Yu Kyung Cho
No abstract text is available yet for this article.
July 30, 2018: Journal of Neurogastroenterology and Motility
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