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Journal of Neurogastroenterology and Motility

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https://www.readbyqxmd.com/read/29179287/interest-of-anorectal-manometry-during-long-term-follow-up-of-patients-operated-on-for-hirschsprung-s-disease
#1
Viet Q Tran, Tania Mahler, Patrick Bontems, Dinh Q Truong, Annie Robert, Philippe Goyens, Henri Steyaert
Background/Aims: Although many advances in the management of Hirschsprung's disease have recently been achieved, postoperative outcomes of these patients remain difficult in a non-negligible number of cases. Therefore, this study aims at investigating characteristics of anorectal manometry and its relationship with postoperative outcomes during long-term follow-up in Hirschsprung patients. Methods: Patients over 4 years of age operated on for Hirschsprung's disease were interviewed to complete detailed questionnaires on bowel function...
November 25, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29156514/esophageal-baseline-impedance-reflects-mucosal-integrity-and-predicts-symptomatic-outcome-with-proton-pump-inhibitor-treatment
#2
Chenxi Xie, Daniel Sifrim, Yuwen Li, Minhu Chen, Yinglian Xiao
Background/Aims: Esophageal baseline impedance, which is decreased in gastroesophageal reflux disease (GERD) patients, is related to the severity of acid reflux and the integrity of the esophageal mucosa. The study aims to compare the baseline impedance and the dilated intercellular spaces (DIS) within patients with typical reflux symptoms and to evaluate the correlation of baseline impedance with DIS, esophageal acid exposure, as well as the efficacy of proton pump inhibitor (PPI) treatment...
November 21, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992679/a-rare-cause-of-acute-colonic-pseudo-obstruction-ogilvie-s-syndrome-caused-by-herpes-zoster
#3
LETTER
Jae Yoon Chung, Jong Seol Park, Yong Sung Kim
No abstract text is available yet for this article.
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992678/alterations-of-food-specific-serum-igg4-titers-to-common-food-antigens-in-patients-with-irritable-bowel-syndrome
#4
Hong Sub Lee, Kwang Jae Lee
Background/Aims: The role of dietary factors in the pathogenesis of irritable bowel syndrome (IBS) is still unclear. The aim of this study was to compare IgG4 levels to common food antigens between patients with IBS and healthy controls. Methods: Thirty-two patients diagnosed as IBS according to the Rome III criteria (12 diarrhea subgroup; 20 non-diarrhea subgroup) and 32 sex and age-matched healthy controls participated in the study. Serum IgG4 titers to 90 common foods were measured in each subject...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992677/nationwide-multicenter-study-for-overlaps-of-common-functional-gastrointestinal-disorders-in-korean-patients-with-constipation
#5
Kyung Sik Park, Sam Ryong Jee, Bong Eun Lee, Kyoung Sup Hong, Jeong Eun Shin, Soo-Young Na, Joong Goo Kwon, Suck Chei Choi, Yong Sung Kim, Hyun Seok Lee, Tae Hee Lee, Kyeong Ok Kim, Jongkyoung Choi, Hee Seok Moon, Yeon Soo Kim, Moo In Park, Soo Jung Park, Seon-Young Park, Sung Noh Hong
Background/Aims: In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we investigated the patterns of overlaps between constipation and other common FGIDs. Methods: This study was designed as a prospective nationwide multi-center questionnaire study using Rome III questionnaires for functional dyspepsia (FD), irritable bowel syndrome (IBS), and functional constipation (FC), as well as various questionnaires about patients' information, degree of symptoms, and quality of life...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992676/intravenous-corticotropin-releasing-hormone-administration-increases-esophageal-electrical-sensitivity-in-healthy-individuals
#6
Takahisa Yamasaki, Toshihiko Tomita, Mayu Takimoto, Takashi Kondo, Katsuyuki Tozawa, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
Background/Aims: When a person is experiencing stress, corticotropin-releasing hormone (CRH) can modulate gut physiologies, such as visceral sensation or gastrointestinal motility, and its intravenous administration mimics stress-induced physiological changes. However, the influence of CRH on the esophagus is yet unknown. Accordingly, we investigated whether intravenous CRH administration increases esophageal sensitivity to electrical stimulation in healthy Japanese subjects. Methods: Twenty healthy subjects were recruited...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992675/relationship-between-salivary-pepsin-concentration-and-esophageal-mucosal-integrity-in-patients-with-gastroesophageal-reflux-disease
#7
Yu-Wen Li, Daniel Sifrim, Chenxi Xie, Minhu Chen, Ying-Lian Xiao
Background/Aims: Increased salivary pepsin could indicate an increase in gastro-esophageal reflux, however, previous studies failed to demonstrate a correlation between salivary pepsin concentrations and 24-hour esophageal acid exposure. This study aims to detect the salivary pepsin and to evaluate the relationship between salivary pepsin concentrations and intercellular spaces (IS) in different gastroesophageal reflux disease phenotypes in patients. Methods: A total of 45 patients and 11 healthy volunteers were included in this study...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992674/is-helicobacter-pylori-associated-functional-dyspepsia-correlated-with-dysbiosis
#8
REVIEW
Yeon-Ji Kim, Woo Chul Chung, Byung Wook Kim, Sung Soo Kim, Jin Il Kim, Na Jin Kim, Jinho Yoo, Soo Hwan Kim
Background/Aims: To assess the long-term effect of Helicobacter pylori eradication on symptomatic improvement according to the type of antibiotic and the duration of treatment in H. pylori-associated functional dyspepsia. Methods: We searched Pubmed, Embase, CINAHL, and the Cochrane library databases for randomized controlled trials written in English and undertaken up to August 2016 that met our eligibility criteria. The search methodology used combinations of the following keywords: Helicobacter pylori OR H...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992673/reflux-hypersensitivity-a-new-functional-esophageal-disorder
#9
REVIEW
Takahisa Yamasaki, Ronnie Fass
Reflux hypersensitivity, recently introduced by Rome IV as a new functional esophageal disorder, is currently considered as the presence of typical heartburn symptoms in patients with normal upper endoscopy and esophageal biopsies, normal esophageal pH test and with evidence of a close correlation between patients' heartburn and reflux events. Reflux hypersensitivity is very common and together with functional heartburn accounts for more than 90% of the heartburn patients who failed treatment with proton pump inhibitor twice daily...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992672/the-clinical-implications-of-overlap-between-constipation-and-common-functional-gastrointestinal-disorders
#10
EDITORIAL
Kang Nyeong Lee
No abstract text is available yet for this article.
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992671/can-acute-stress-cause-esophageal-hypersensitivity-in-healthy-individuals
#11
EDITORIAL
Yu Kyung Cho
No abstract text is available yet for this article.
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28874043/gastroesophageal-reflux-disease-could-progress-to-achalasia
#12
LETTER
Laura Bognar, Andras Vereczkei, Ors Peter Horvath
No abstract text is available yet for this article.
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28866876/understanding-the-chicago-classification-from-tracings-to-patients
#13
REVIEW
Francisco Schlottmann, Fernando A Herbella, Marco G Patti
Current parameters of the Chicago classification include assessment of the esophageal body (contraction vigour and peristalsis), lower esophageal sphincter relaxation pressure, and intra-bolus pressure pattern. Esophageal disorders include achalasia, esophagogastric junction outflow obstruction, major disorders of peristalsis, and minor disorders of peristalsis. Sub-classification of achalasia in types I, II, and III seems to be useful to predict outcomes and choose the optimal treatment approach. The real clinical significance of other new parameters and disorders is still under investigation...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28774159/comparison-of-changes-in-the-interstitial-cells-of-cajal-and-neuronal-nitric-oxide-synthase-positive-neuronal-cells-with-aging-between-the-ascending-and-descending-colon-of-f344-rats
#14
Sun Min Lee, Nayoung Kim, Hyun Jin Jo, Ji Hyun Park, Ryoung Hee Nam, Hye Seung Lee, Hyun Jin Kim, Moon Young Lee, Yong Sung Kim, Dong Ho Lee
Background/Aims: Neuronal degeneration and changes in interstitial cells of Cajal (ICCs) are important mechanisms of age-related constipation. This study aims to compare the distribution of ICCs and neuronal nitric oxide synthase (nNOS) with regard to age-related changes between the ascending colon (AC) and descending colon (DC) in 6-, 31-, and 74-week old and 2-year old male Fischer-344 rats. Methods: The amount of fecal pellet and the bead expulsion times were measured...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28750491/severe-delayed-gastric-emptying-induces-non-acid-reflux-up-to-proximal-esophagus-in-neurologically-impaired-patients
#15
Shinji Ishii, Suguru Fukahori, Kimio Asagiri, Yoshiaki Tanaka, Nobuyuki Saikusa, Naoki Hashizume, Motomu Yoshida, Daisuke Masui, Naoko Komatsuzaki, Naruki Higashidate, Saki Sakamoto, Tomohiro Kurahachi, Shiori Tsuruhisa, Hirotomo Nakahara, Minoru Yagi
Background/Aims: The aim of this study is to investigate the degree of delayed gastric emptying (DGE) and evaluate how the severity of DGE affects gastroesophageal reflux disease (GERD) in neurologically impaired (NI) patients utilizing 24-hour multichannel intraluminal impedance pH measurements (pH/MII) and (13)C-acetate breath test ((13)C-ABT) analyses. Methods: (13)C-ABT and pH/MII were conducted in 26 NI patients who were referred to our institution due to suspected GERD...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28738452/prediction-of-delayed-colonic-transit-using-bristol-stool-form-and-stool-frequency-in-eastern-constipated-patients-a-difference-from-the-west
#16
Veeravich Jaruvongvanich, Tanisa Patcharatrakul, Sutep Gonlachanvit
Background/Aims: The correlation between the Bristol stool form scale (BSFS) and colonic transit time (CTT) has been reported in Western populations. Our study aims to study the relationship between BSFS, stool frequency, and CTT in Eastern patients with chronic constipation. Methods: A total of 144 chronic functional constipation patients underwent colonic transit study by using radio-opaque markers, anorectal manometry, and balloon expulsion test. Stool diary including stool forms and frequency was recorded...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28738451/psychiatric-co-morbidity-in-patients-with-irritable-bowel-syndrome-at-a-tertiary-care-center-in-northern-india
#17
Yuman Kawoos, Zaid A Wani, Showkat A Kadla, Irfan A Shah, Arshad Hussain, M Maqbool Dar, Mushtaq A Margoob, Kouser Sideeq
Background/Aims: Irritable bowel syndrome (IBS) is a chronic psycho-physiological disorder. It is considered to be the most common functional gastrointestinal disorder, and about 50-90% of IBS patients have associated psychiatric co-morbidity. We aimed to study psychiatric co-morbidities in patients with IBS visiting a tertiary care center. Methods: This was a cross-sectional case-control study conducted over a duration of one and a half years from January 2014 to July 2015...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28571122/detecting-the-non-physiological-surgically-tailored-ileocolic-anastomosis-using-the-wireless-motility-capsule-a-pre-and-post-operative-prospective-within-subject-trial
#18
Yngve Thorsen, Bojan V Stimec, Jens M Nesgaard, Dejan Ignjatovic
Background/Aims: Wireless motility capsule (WMC) detects the ileocolic junction (ICJ) in most non-operated patients. We find no data concerning this examination in patients where the ileocolic valve is replaced by a per definition incompetent, surgically created ICJ. We wanted to see if WMC could detect the ICJ after a right colectomy and assess the competency. Methods: Prospective cohort study using a within-subject design to eliminate subject-subject variability...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28554984/the-effect-of-deoxycholic-acid-on-secretion-and-motility-in-the-rat-and-guinea-pig-large-intestine
#19
Nam Hee Kim, Jung Ho Park, Jae-Soon Park, Yeun-Ho Joung
Background/Aims: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon and coordination of bowel movements in the guinea pig colon. Methods: The short-circuit current from the mucosal strip of the proximal and distal rat colon was compared under control conditions after induction of secretion with deoxycholic acid (DCA) as well as after inhibition of secretion with indomethacin, 1,2-bis (o-aminophenoxy) ethane-N,N,N',N'-tetra-acetic acid (an intracellular calcium chelator; BAPTA), and tetrodotoxin (TTX) using an Ussing chamber...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28545185/the-ability-of-the-eating-assessment-tool-10-to-detect-aspiration-in-patients-with-neurological-disorders
#20
Selen Serel Arslan, Numan Demir, Hasan E Kılınç, Aynur A Karaduman
Background/Aims: Dysphagia is common in patients with neurological disorders. There is a need to identify patients at risk early by a useful clinical tool to prevent its serious complications. The study aims to determine the ability of the Turkish version of Eating Assessment Tool-10 (T-EAT-10) to detect aspiration in patients with neurological disorders. Methods: Two hundred fifty-nine patients with neurological disorders who had complaints about swallowing difficulty and referred for a swallowing evaluation were included...
October 30, 2017: Journal of Neurogastroenterology and Motility
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