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Journal of Neurogastroenterology and Motility

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https://www.readbyqxmd.com/read/28571122/detecting-the-non-physiological-surgically-tailored-ileocolic-anastomosis-using-the-wireless-motility-capsule-a-pre-and-post-operative-prospective-within-subject-trial
#1
Yngve Thorsen, Bojan V Stimec, Jens M Nesgaard, Dejan Ignjatovic
Background/Aims: Wireless motility capsule (WMC) detects the ileocolic junction (ICJ) in most non-operated patients. We find no data concerning this examination in patients where the ileocolic valve is replaced by a per definition incompetent, surgically created ICJ. We wanted to see if WMC could detect the ICJ after a right colectomy and assess the competency. Methods: Prospective cohort study using a within-subject design to eliminate subject-subject variability...
June 1, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28554984/the-effect-of-deoxycholic-acid-on-secretion-and-motility-in-the-rat-and-guinea-pig-large-intestine
#2
Nam Hee Kim, Jung Ho Park, Jae-Soon Park, Yeun-Ho Joung
Background/Aims: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon and coordination of bowel movements in the guinea pig colon. Methods: The short-circuit current from the mucosal strip of the proximal and distal rat colon was compared under control conditions after induction of secretion with deoxycholic acid (DCA) as well as after inhibition of secretion with indomethacin, 1,2-bis (o-aminophenoxy) ethane-N, N,N',N'-tetra-acetic acid (an intracellular calcium chelator; BAPTA), and tetrodotoxin (TTX) using an Ussing chamber...
May 29, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28545185/the-ability-of-the-eating-assessment-tool-10-to-detect-aspiration-in-patients-with-neurological-disorders
#3
Selen Serel Arslan, Numan Demir, Hasan E Kılınç, Aynur A Karaduman
Background/Aims: Dysphagia is common in patients with neurological disorders. There is a need to identify patients at risk early by a useful clinical tool to prevent its serious complications. The study aims to determine the ability of the Eating Assessment Tool-10 (EAT-10) to detect aspiration in patients with neurological disorders. Methods: Two hundred fifty-nine patients with neurological disorders who had complaints about swallowing difficulty and referred for a swallowing evaluation were included...
May 24, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28478663/early-assessment-of-cost-effectiveness-of-gastric-electrical-stimulation-for-diabetic-nausea-and-vomiting
#4
Mette W Klinge, Peter Rask, Lene S Mortensen, Kathrine Lassen, Niels Ejskjaer, Lars H Ehlers, Klaus Krogh
Background/Aims: Recurrent nausea and/or vomiting are common complications of diabetes mellitus. The conditions severely impact the quality of life of patients and often cause repeated admissions to hospital incurring significant healthcare costs. If standard treatment fails, gastric electrical stimulation (GES) may be offered in selected cases, as a minimally invasive, but expensive, therapeutic option. Our aims are to evaluate the clinical effect and the cost-utility of GES as a treatment for severe diabetic recurrent nausea and/or vomiting...
May 4, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672434/effects-of-age-on-esophageal-motility-use-of-high-resolution-esophageal-impedance-manometry
#5
Young Kwang Shim, Nayoung Kim, Yo Han Park, Jong-Chan Lee, Jihee Sung, Yoon Jin Choi, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
The data "268" in the Abstract should have been written as "279" and the data "277" in the Materials and Methods should have been written as "279."
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672433/the-increased-level-of-depression-and-anxiety-in-irritable-bowel-syndrome-patients-compared-with-healthy-controls-systematic-review-and-meta-analysis
#6
REVIEW
Changhyun Lee, Eunyoung Doo, Ji Min Choi, Seung-Ho Jang, Han-Seung Ryu, Ju Yup Lee, Jung Hwan Oh, Jung Ho Park, Yong Sung Kim
Background/Aims: Irritable bowel syndrome (IBS) patients commonly experience psychiatric disorders, such as depression and anxiety. This meta-analysis sought to compare depression and anxiety levels between IBS patients and healthy controls. Methods: We searched major electronic databases (PubMed, EMBASE, MEDLINE, and Cochrane library) to find comparative studies on IBS patients and healthy controls. The primary outcome was a standardized mean difference (SMD) of anxiety and depression levels; sub-group analyses were conducted according to IBS-subtypes...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672432/pros-and-cons-while-looking-through-an-asian-window-on-the-rome-iv-criteria-for-irritable-bowel-syndrome-pros
#7
REVIEW
Uday C Ghoshal
A decade after Rome III, in 2016, Rome IV criteria were published. There are major differences between Rome IV and the earlier iteration, some of which are in line with Asian viewpoints. The clinical applicability of the Rome IV criteria of irritable bowel syndrome (IBS) in Asian perspective is reviewed here. Instead of considering functional gastrointestinal disorders (FGIDs) to be largely psychogenic, Rome IV suggested the importance of the gut over brain ("disorders of gut-brain interaction" not "brain-gut interaction")...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672431/the-application-of-the-rome-iv-criteria-to-functional-esophagogastroduodenal-disorders-in-asia
#8
REVIEW
Hidekazu Suzuki
The Rome criteria were amended as Rome IV. For functional esophageal disorders, the exclusion criteria have been more specifically revised based on further understanding of other esophageal disorders, including eosinophilic esophagitis and spastic and hypercontractile motor disorders. Another revised point is the more restrictive definition of gastroesophageal reflux disease, indicating that sensitivity to a physiological reflux burden may be placed more firmly within the functional group. For functional dyspepsia (FD), only minor changes were introduced, mainly to improve specificity...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672430/the-implication-of-gastric-dysmotility-in-the-pathophysiology-of-functional-dyspepsia
#9
EDITORIAL
Yang Won Min
No abstract text is available yet for this article.
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28672429/regional-food-causing-symptoms-of-gastroesophageal-reflux-disease
#10
EDITORIAL
Jung Ho Park
No abstract text is available yet for this article.
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28586765/lipid-laden-macrophages-in-respiratory-disease
#11
LETTER
Laura R Sadofsky, Yvette A Hayman, Simon P Hart, Alyn H Morice
No abstract text is available yet for this article.
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28578564/balloon-expulsion-test-does-not-seem-to-be-useful-for-screening-or-exclusion-of-dyssynergic-defecation-as-a-single-test
#12
Jooyoung Lee, Kyoung Sup Hong, Joo Sung Kim, Hyun Chae Jung
Background/Aims: Balloon expulsion test (BET) is regarded as a screening tool of dyssynergic defecation (DD). However, some patients with normal BET results may be treated effectively by biofeedback training. This study aims to validate BET as a single screening test. Methods: Two hundred and thirty-two patients who were diagnosed with functional constipation or irritable bowel syndrome with constipation who underwent anorectal manometry (ARM) and BET at Seoul National University Hospital were enrolled...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28565730/gallbladder-volume-indicated-for-gallbladder-dysmotility
#13
LETTER
Linlin Liu, Bing Wu, Jianlin Lv
No abstract text is available yet for this article.
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28551943/targeting-histamine-receptors-in-irritable-bowel-syndrome-a-critical-appraisal
#14
REVIEW
Adam Fabisiak, Jakub Włodarczyk, Natalia Fabisiak, Martin Storr, Jakub Fichna
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for agents targeting histamine receptors as a potential therapeutic option in clinical treatment. In this review, the role of histamine and histamine receptors is debated. Moreover, the clinical evidence of anti-histamine therapeutics in irritable bowel syndrome is discussed...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28480684/effects-of-cognitive-behavior-therapy-on-heart-rate-variability-in-young-females-with-constipation-predominant-irritable-bowel-syndrome-a-parallel-group-trial
#15
Aelee Jang, Sun-Kyung Hwang, Nikhil S Padhye, Janet C Meininger
Background/Aims: The relation between heart rate variability (HRV) as non-invasive biomarkers of autonomic function and cognitive behavior therapy (CBT) as non-pharmacological treatments has rarely been examined in patients with constipation-predominant irritable bowel syndrome (IBS-C). The purpose of this study is to evaluate the efficacy of an 8-week CBT intervention on HRV and IBS symptoms, and the correlation of changes in HRV with changes in IBS symptoms among young female nursing students with IBS-C...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28478662/the-degree-of-disease-knowledge-in-patients-with-gastroesophageal-reflux-disease-a-multi-center-prospective-study-in-korea
#16
In Du Jeong, Moo In Park, Sung Eun Kim, Beom Jin Kim, Sang Wook Kim, Jie-Hyun Kim, Hye Young Sung, Tae-Hoon Oh, Yeon Soo Kim
Background/Aims: Patient education has been shown to be beneficial in several diseases. To properly educate patients with gastroesophageal reflux disease (GERD), it is necessary to understand how much they already know about their disease. However, no study has examined the degree of disease knowledge in Korean patients with GERD. Therefore, we conducted this study to assess the degree of knowledge in such patients. Methods: This multicenter prospective study was conducted from January 2014 to January 2015...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28460516/neuroendocrine-dysregulation-in-irritable-bowel-syndrome-patients-a-pilot-study
#17
Cristina Stasi, Massimo Bellini, Dario Gambaccini, Emiliano Duranti, Nicola de Bortoli, Bernardo Fani, Eleonora Albano, Salvatore Russo, Isabella Sudano, Giacomo Laffi, Stefano Taddei, Santino Marchi, Rosa Maria Bruno
Background/Aims: Irritable bowel syndrome (IBS) is a multifactorial disorder, involving dysregulation of brain-gut axis. Our aim was to evaluate the neuroendocrine activity in IBS. Methods: Thirty IBS and 30 healthy volunteers were enrolled. Psychological symptoms were evaluated by questionnaires. Urinary 5-hydroxyindoleacetic acid, plasma serotonin (5-hydroxytryptamine, 5-HT), endothelin, and neuropeptide Y (NPY), and plasma and urinary cortisol levels were evaluated...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28423481/prevalence-of-gastric-motility-disorders-in-patients-with-functional-dyspepsia
#18
Haruki Asano, Toshihiko Tomita, Kumiko Nakamura, Takahisa Yamasaki, Takuya Okugawa, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Kazuhito Fukushima, Shozo Hirota, Jiro Watari, Hiroto Miwa
Background/Aims: Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dyspeptic symptoms using gastric scintigraphy in the PDS type of FD. Methods: Forty healthy subjects and 94 PDS type FD patients were enrolled in the study...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28351117/clinical-characteristics-of-patients-with-untreated-achalasia
#19
Han Ho Jeon, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jeffrey L Conklin
Background/Aims: Patients with untreated achalasia frequently complain of heartburn and regurgitation. The diagnosis of achalasia might be delayed because these symptoms are misinterpreted as gastroesophageal reflux. We aim to evaluate the clinical, radiologic, and manometric findings in patient with untreated achalasia. Methods: The records of patients diagnosed with primary achalasia between July 2004 and January 2012 at Gangnam Severance Hospital, Seoul, Korea were evaluated...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28343377/protein-kinase-c-mediates-the-corticosterone-induced-sensitization-of-dorsal-root-ganglion-neurons-innervating-the-rat-stomach
#20
Meng Li, Lu Xue, Hong-Yan Zhu, Hongjun Wang, Xue Xu, Ping-An Zhang, Geping Wu, Guang-Yin Xu
Background/Aims: Gastric hypersensitivity contributes to abdominal pain in patients with functional dyspepsia. Recent studies showed that hormones induced by stress are correlated with visceral hypersensitivity. However, the precise mechanisms underlying gastric hypersensitivity remain largely unknown. The aim of the present study was designed to investigate the roles of corticosterone (CORT) on excitability of dorsal root ganglion (DRG) neurons innervating the stomach. Methods: DRG neurons innervating the stomach were labeled by DiI injection into the stomach wall...
July 30, 2017: Journal of Neurogastroenterology and Motility
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