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Journal of Neurogastroenterology and Motility

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https://www.readbyqxmd.com/read/28586765/lipid-laden-macrophages-in-respiratory-disease
#1
LETTER
Laura R Sadofsky, Yvette A Hayman, Simon P Hart, Alyn H Morice
No abstract text is available yet for this article.
June 6, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28578564/balloon-expulsion-test-does-not-seem-to-be-useful-for-screening-or-exclusion-of-dyssynergic-defecation-as-a-single-test
#2
Jooyoung Lee, Kyoung Sup Hong, Joo Sung Kim, Hyun Chae Jung
Background/Aims: Balloon expulsion test (BET) is regarded as a screening tool of dyssynergic defecation (DD). However, some patients with normal BET results may be treated effectively by biofeedback training. This study aims to validate BET as a single screening test. Methods: Two hundred and thirty-two patients who were diagnosed with functional constipation or irritable bowel syndrome with constipation who underwent anorectal manometry (ARM) and BET at Seoul National University Hospital were enrolled...
June 4, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28571122/detecting-the-non-physiological-surgically-tailored-ileocolic-anastomosis-using-the-wireless-motility-capsule-a-pre-and-post-operative-prospective-within-subject-trial
#3
Yngve Thorsen, Bojan V Stimec, Jens M Nesgaard, Dejan Ignjatovic
Background/Aims: Wireless motility capsule (WMC) detects the ileocolic junction (ICJ) in most non-operated patients. We find no data concerning this examination in patients where the ileocolic valve is replaced by a per definition incompetent, surgically created ICJ. We wanted to see if WMC could detect the ICJ after a right colectomy and assess the competency. Methods: Prospective cohort study using a within-subject design to eliminate subject-subject variability...
June 1, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28565730/gallbladder-volume-indicated-for-gallbladder-dysmotility
#4
LETTER
Linlin Liu, Bing Wu, Jianlin Lv
No abstract text is available yet for this article.
June 1, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28554984/the-effect-of-deoxycholic-acid-on-secretion-and-motility-in-the-rat-and-guinea-pig-large-intestine
#5
Nam Hee Kim, Jung Ho Park, Jae-Soon Park, Yeun-Ho Joung
Background/Aims: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon and coordination of bowel movements in the guinea pig colon. Methods: The short-circuit current from the mucosal strip of the proximal and distal rat colon was compared under control conditions after induction of secretion with deoxycholic acid (DCA) as well as after inhibition of secretion with indomethacin, 1,2-bis (o-aminophenoxy) ethane-N, N,N',N'-tetra-acetic acid (an intracellular calcium chelator; BAPTA), and tetrodotoxin (TTX) using an Ussing chamber...
May 29, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28551943/targeting-histamine-receptors-in-irritable-bowel-syndrome-a-critical-appraisal
#6
REVIEW
Adam Fabisiak, Jakub Włodarczyk, Natalia Fabisiak, Martin Storr, Jakub Fichna
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for agents targeting histamine receptors as a potential therapeutic option in clinical treatment. In this review, the role of histamine and histamine receptors is debated. Moreover, the clinical evidence of anti-histamine therapeutics in irritable bowel syndrome is discussed...
May 27, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28545185/the-ability-of-the-eating-assessment-tool-10-to-detect-aspiration-in-patients-with-neurological-disorders
#7
Selen Serel Arslan, Numan Demir, Hasan E Kılınç, Aynur A Karaduman
Background/Aims: Dysphagia is common in patients with neurological disorders. There is a need to identify patients at risk early by a useful clinical tool to prevent its serious complications. The study aims to determine the ability of the Eating Assessment Tool-10 (EAT-10) to detect aspiration in patients with neurological disorders. Methods: Two hundred fifty-nine patients with neurological disorders who had complaints about swallowing difficulty and referred for a swallowing evaluation were included...
May 24, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28480684/effects-of-cognitive-behavior-therapy-on-heart-rate-variability-in-young-females-with-constipation-predominant-irritable-bowel-syndrome-a-parallel-group-trial
#8
Aelee Jang, Sun-Kyung Hwang, Nikhil S Padhye, Janet C Meininger
Background/Aims: The relation between heart rate variability (HRV) as non-invasive biomarkers of autonomic function and cognitive behavior therapy (CBT) as non-pharmacological treatments has rarely been examined in patients with constipation-predominant irritable bowel syndrome (IBS-C). The purpose of this study was to evaluate the efficacy of an 8-week CBT intervention on HRV and IBS symptoms, and the correlation of changes in HRV with changes in IBS symptoms among young female nursing students with IBS-C...
May 8, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28478663/early-assessment-of-cost-effectiveness-of-gastric-electrical-stimulation-for-diabetic-nausea-and-vomiting
#9
Mette W Klinge, Peter Rask, Lene S Mortensen, Kathrine Lassen, Niels Ejskjaer, Lars H Ehlers, Klaus Krogh
Background/Aims: Recurrent nausea and/or vomiting are common complications of diabetes mellitus. The conditions severely impact the quality of life of patients and often cause repeated admissions to hospital incurring significant healthcare costs. If standard treatment fails, gastric electrical stimulation (GES) may be offered in selected cases, as a minimally invasive, but expensive, therapeutic option. Our aims are to evaluate the clinical effect and the cost-utility of GES as a treatment for severe diabetic recurrent nausea and/or vomiting...
May 4, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28478662/the-degree-of-disease-knowledge-in-patients-with-gastroesophageal-reflux-disease-a-multi-center-prospective-study-in-korea
#10
In Du Jeong, Moo In Park, Sung Eun Kim, Beom Jin Kim, Sang Wook Kim, Jie-Hyun Kim, Hye Young Sung, Tae-Hoon Oh, Yeon Soo Kim
Background/Aims: Patient education has been shown to be beneficial in several diseases. To properly educate patients with gastroesophageal reflux disease (GERD), it is necessary to understand how much they already know about their disease. However, no study has examined the degree of disease knowledge in Korean patients with GERD. Therefore, we conducted this study to assess the degree of knowledge in such patients. Methods: This multicenter prospective study was conducted from January 2014 to January 2015...
May 4, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28460516/neuroendocrine-dysregulation-in-irritable-bowel-syndrome-patients-a-pilot-study
#11
Cristina Stasi, Massimo Bellini, Dario Gambaccini, Emiliano Duranti, Nicola de Bortoli, Bernardo Fani, Eleonora Albano, Salvatore Russo, Isabella Sudano, Giacomo Laffi, Stefano Taddei, Santino Marchi, Rosa Maria Bruno
Background/Aims: Irritable bowel syndrome (IBS) is a multifactorial disorder, involving dysregulation of brain-gut axis. Our aim was to evaluate the neuroendocrine activity in IBS. Methods: Thirty IBS and 30 healthy subjects were enrolled. Psychological symptoms were evaluated by questionnaires. Urinary 5-hydroxyindoleacetic acid (5-HIAA), plasma serotonin, endothelin, neuropeptide Y (NPY), plasma, and urinary cortisol levels were evaluated. Fourteen IBS subjects underwent microneurography to obtain multiunit recordings of efferent postganglionic muscle sympathetic nerve activity (MSNA)...
April 26, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28423481/prevalence-of-gastric-motility-disorders-in-patients-with-functional-dyspepsia
#12
Haruki Asano, Toshihiko Tomita, Kumiko Nakamura, Takahisa Yamasaki, Takuya Okugawa, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Kazuhito Fukushima, Shozo Hirota, Jiro Watari, Hiroto Miwa
Background/Aims: Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dyspeptic symptoms using gastric scintigraphy in the PDS type of FD. Methods: Forty healthy subjects and 94 PDS type FD patients were enrolled in the study...
April 19, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28351117/clinical-characteristics-of-patients-with-untreated-achalasia
#13
Han Ho Jeon, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jeffrey L Conklin
Background/Aims: Patients with untreated achalasia frequently complain of heartburn and regurgitation. The diagnosis of achalasia might be delayed because these symptoms are misinterpreted as gastroesophageal reflux. We aim to evaluate the clinical presentation, radiologic, and manometric findings in patient untreated achalasia. Methods: The records of patients diagnosed with primary achalasia between July 2004 and January 2012 at Gangnam Severance Hospital, Seoul, Korea were evaluated...
March 28, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28343377/protein-kinase-c-mediates-the-corticosterone-induced-sensitization-of-dorsal-root-ganglion-neurons-innervating-the-rat-stomach
#14
Meng Li, Lu Xue, Hong-Yan Zhu, Hongjun Wang, Xue Xu, Geping Wu, Guang-Yin Xu
Background/Aims: Gastric hypersensitivity contributes to abdominal pain in patients with functional dyspepsia (FD). Recent studies showed that hormones induced by stress are correlated with visceral hypersensitivity. However, the precise mechanisms underlying gastric hypersensitivity remain largely unknown. The aim of the present study was designed to investigate the roles of corticosterone (CORT) on excitability of dorsal root ganglion (DRG) neurons innervating the stomach. Methods: DRG neurons innervating the stomach were labeled by DiI injection into the stomach wall...
March 26, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28372039/can-nocturnal-acid-breakthrough-be-reduced-by-long-acting-proton-pump-inhibitors
#15
EDITORIAL
Hye Kyung Jeon, Gwang Ha Kim
No abstract text is available yet for this article.
April 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28274109/what-is-new-in-rome-iv
#16
REVIEW
Max J Schmulson, Douglas A Drossman
Functional gastrointestinal disorders (FGIDs) are diagnosed and classified using the Rome criteria; the criteria may change over time as new scientific data emerge. The Rome IV was released in May 2016. The aim is to review the main changes in Rome IV. FGIDs are now called disorders of gut-brain interaction (DGBI). Rome IV has a multicultural rather than a Western-culture focus. There are new chapters including multicultural, age-gender-women's health, intestinal microenvironment, biopsychosocial, and centrally mediated disorders...
April 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28260282/the-evidence-of-da-9701-on-bowel-motility
#17
LETTER
Mingjie Wang, Jianlin Lv, Meng Xia
No abstract text is available yet for this article.
April 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28256119/how-to-perform-and-interpret-functional-magnetic-resonance-imaging-studies-in-functional-gastrointestinal-disorders
#18
REVIEW
In-Seon Lee, Hubert Preissl, Paul Enck
Functional neuroimaging studies have revealed the importance of the role of cognitive and psychological factors and the dysregulation of the brain-gut axis in functional gastrointestinal disorder patients. Although only a small number of neuroimaging studies have been conducted in functional gastrointestinal disorder patients, and despite the fact that the neuroimaging technique requires a high level of knowledge, the technique still has a great deal of potential. The application of functional magnetic resonance imaging (fMRI) technique in functional gastrointestinal disorders should provide novel methods of diagnosing and treating patients...
April 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28249379/clinical-usefulness-of-fecal-microbiota-transplantation
#19
EDITORIAL
Jung Ho Park
No abstract text is available yet for this article.
April 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28249378/relevance-of-measuring-substances-in-bronchoalveolar-lavage-fluid-for-detecting-aspiration-associated-extraesophageal-reflux-disease
#20
LETTER
Edoardo Savarino, Patrizia Zentilin, Elisa Marabotto, Vincenzo Savarino
No abstract text is available yet for this article.
April 30, 2017: Journal of Neurogastroenterology and Motility
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