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Journal of Pathology Informatics

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https://www.readbyqxmd.com/read/29770255/a-method-for-the-interpretation-of-flow-cytometry-data-using-genetic-algorithms
#1
Cesar Angeletti
Background: Flow cytometry analysis is the method of choice for the differential diagnosis of hematologic disorders. It is typically performed by a trained hematopathologist through visual examination of bidimensional plots, making the analysis time-consuming and sometimes too subjective. Here, a pilot study applying genetic algorithms to flow cytometry data from normal and acute myeloid leukemia subjects is described. Subjects and Methods: Initially, Flow Cytometry Standard files from 316 normal and 43 acute myeloid leukemia subjects were transformed into multidimensional FITS image metafiles...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29770254/patient-portal-access-to-diagnostic-test-results
#2
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29721362/career-paths-of-pathology-informatics-fellowship-alumni
#3
Joseph W Rudolf, Christopher A Garcia, Matthew G Hanna, Christopher L Williams, Ulysses G Balis, Liron Pantanowitz, J Mark Tuthill, John R Gilbertson
Background: The alumni of today's Pathology Informatics and Clinical Informatics fellowships fill diverse roles in academia, large health systems, and industry. The evolving training tracks and curriculum of Pathology Informatics fellowships have been well documented. However, less attention has been given to the posttraining experiences of graduates from informatics training programs. Here, we examine the career paths of subspecialty fellowship-trained pathology informaticians. Methods: Alumni from four Pathology Informatics fellowship training programs were contacted for their voluntary participation in the study...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29721361/constant-quest-for-quality-digital-cytopathology
#4
Simone L Van Es, Janelle Greaves, Stephanie Gay, Jennifer Ross, Derek Holzhauser, Tony Badrick
Background: Special consideration should be given when creating and selecting cytopathology specimens for digitization to maximize quality. Advances in scanning and viewing technology can also improve whole-slide imaging (WSI) output quality. Methods: Accumulated laboratory experience with digitization of glass cytopathology slides was collected. Results: This paper describes characteristics of a cytopathology glass slide that can reduce quality on resulting WSI...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29721360/psychological-aspects-of-utilizing-telecytology-for-rapid-on-site-adequacy-assessments
#5
Aparna Mahajan, Suzanne Selvaggi, Liron Pantanowitz
Rapid On-Site Evaluation (ROSE) has been well documented in its ability to improve the diagnostic yield and accuracy of fine needle aspirations across many sites, resulting in better quality of patient management and a simultaneous reduction in treatment costs. Telecytology makes it possible for cytology laboratories to offer ROSE in a cost effective manner, whilst employing only a small number of trained cytopathologists to cover many sites from a single connected location. However, the adoption of telecytology for ROSE has been lackluster...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29692947/implementation-of-a-mobile-clinical-decision-support-application-to-augment-local-antimicrobial-stewardship
#6
Brian M Hoff, Diana C Ford, Dilek Ince, Erika J Ernst, Daniel J Livorsi, Brett H Heintz, Vincent Masse, Michael J Brownlee, Bradley A Ford
Background: Medical applications for mobile devices allow clinicians to leverage microbiological data and standardized guidelines to treat patients with infectious diseases. We report the implementation of a mobile clinical decision support (CDS) application to augment local antimicrobial stewardship. Methods: We detail the implementation of our mobile CDS application over 20 months. Application utilization data were collected and evaluated using descriptive statistics to quantify the impact of our implementation...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29692946/electronic-p-chip-based-system-for-identification-of-glass-slides-and-tissue-cassettes-in-histopathology-laboratories
#7
Wlodek Mandecki, Jay Qian, Katie Gedzberg, Maryanne Gruda, Efrain Frank Rodriguez, Leslie Nesbitt, Michael Riben
Background: The tagging system is based on a small, electronic, wireless, laser-light-activated microtransponder named "p-Chip." The p-Chip is a silicon integrated circuit, the size of which is 600 μm × 600 μm × 100 μm. Each p-Chip contains a unique identification code stored within its electronic memory that can be retrieved with a custom reader. These features allow the p-Chip to be used as an unobtrusive and scarcely noticeable ID tag on glass slides and tissue cassettes...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29692945/challenges-in-communication-from-referring-clinicians-to-pathologists-in-the-electronic-health-record-era
#8
Andrea Lynne Barbieri, Oluwole Fadare, Linda Fan, Hardeep Singh, Vinita Parkash
We report on the role played by electronic health record inbox messages (EHRmsg) in a safety event involving pathology. Evolving socio-cultural norms led to the coopting of EHRmsg for alternate use and oversight of a clinician to pathologist request. We retrospectively examined EHR inbox messages to pathologists over a 3 month block. 36 messages from 22 pathologists were assessed. 26 pertained to patient care including requests for report corrections and additional testing. 88% of requests had gone unaddressed...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29692944/the-case-for-an-entropic-simian-in-your-laboratory-the-case-for-laboratory-information-system-failure-scenario-testing-in-the-live-production-environment
#9
Christopher L Williams, David S McClintock, Ulysses G J Balis
No abstract text is available yet for this article.
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29692429/erratum-preconceived-stakeholders-attitude-toward-telepathology-implications-for-successful-implementation
#10
(no author information available yet)
[This corrects the article on p. 50 in vol. 8, PMID: 29416913.].
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29619278/digital-imaging-and-communications-in-medicine-whole-slide-imaging-connectathon-at-digital-pathology-association-pathology-visions-2017
#11
EDITORIAL
David Clunie, Dan Hosseinzadeh, Mikael Wintell, David De Mena, Nieves Lajara, Marcial Garcia-Rojo, Gloria Bueno, Kiran Saligrama, Aaron Stearrett, David Toomey, Esther Abels, Frank Van Apeldoorn, Stephane Langevin, Sean Nichols, Joachim Schmid, Uwe Horchner, Bruce Beckwith, Anil Parwani, Liron Pantanowitz
As digital pathology systems for clinical diagnostic work applications become mainstream, interoperability between these systems from different vendors becomes critical. For the first time, multiple digital pathology vendors have publicly revealed the use of the digital imaging and communications in medicine (DICOM) standard file format and network protocol to communicate between separate whole slide acquisition, storage, and viewing components. Note the use of DICOM for clinical diagnostic applications is still to be validated in the United States...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29619277/deep-learning-nuclei-detection-in-digitized-histology-images-by-superpixels
#12
Sudhir Sornapudi, Ronald Joe Stanley, William V Stoecker, Haidar Almubarak, Rodney Long, Sameer Antani, George Thoma, Rosemary Zuna, Shelliane R Frazier
Background: Advances in image analysis and computational techniques have facilitated automatic detection of critical features in histopathology images. Detection of nuclei is critical for squamous epithelium cervical intraepithelial neoplasia (CIN) classification into normal, CIN1, CIN2, and CIN3 grades. Methods: In this study, a deep learning (DL)-based nuclei segmentation approach is investigated based on gathering localized information through the generation of superpixels using a simple linear iterative clustering algorithm and training with a convolutional neural network...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29531849/initial-assessments-of-e-learning-modules-in-cytotechnology-education
#13
Maheswari S Mukherjee, Amber D Donnelly
Background: Nine E-learning modules (ELMs) were developed in our program using Articulate software. This study assessed our cytotechnology (CT) students' perceptions on the content of the ELMs, and the perceived influence of the ELMs on students' performance during clinical rotations. Subjects and Methods: All CT students watched nine ELMs before the related classroom lecture and group discussion. Following that, students completed nine preclinical rotation surveys...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29531848/commentary-whole-slide-images-good-enough-for-primary-diagnosis
#14
Thomas W Bauer
No abstract text is available yet for this article.
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29531847/a-review-on-the-applications-of-crowdsourcing-in-human-pathology
#15
REVIEW
Roshanak Alialy, Sasan Tavakkol, Elham Tavakkol, Amir Ghorbani-Aghbologhi, Alireza Ghaffarieh, Seon Ho Kim, Cyrus Shahabi
The advent of the digital pathology has introduced new avenues of diagnostic medicine. Among them, crowdsourcing has attracted researchers' attention in the recent years, allowing them to engage thousands of untrained individuals in research and diagnosis. While there exist several articles in this regard, prior works have not collectively documented them. We, therefore, aim to review the applications of crowdsourcing in human pathology in a semi-systematic manner. We first, introduce a novel method to do a systematic search of the literature...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29531846/enabling-histopathological-annotations-on-immunofluorescent-images-through-virtualization-of-hematoxylin-and-eosin
#16
Amal Lahiani, Eldad Klaiman, Oliver Grimm
Context: Medical diagnosis and clinical decisions rely heavily on the histopathological evaluation of tissue samples, especially in oncology. Historically, classical histopathology has been the gold standard for tissue evaluation and assessment by pathologists. The most widely and commonly used dyes in histopathology are hematoxylin and eosin (H&E) as most malignancies diagnosis is largely based on this protocol. H&E staining has been used for more than a century to identify tissue characteristics and structures morphologies that are needed for tumor diagnosis...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29416914/routine-digital-pathology-workflow-the-catania-experience
#17
Filippo Fraggetta, Salvatore Garozzo, Gian Franco Zannoni, Liron Pantanowitz, Esther Diana Rossi
Introduction: Successful implementation of whole slide imaging (WSI) for routine clinical practice has been accomplished in only a few pathology laboratories worldwide. We report the transition to an effective and complete digital surgical pathology workflow in the pathology laboratory at Cannizzaro Hospital in Catania, Italy. Methods: All (100%) permanent histopathology glass slides were digitized at ×20 using Aperio AT2 scanners. Compatible stain and scanning slide racks were employed to streamline operations...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29416913/preconceived-stakeholders-attitude-toward-telepathology-implications-for-successful-implementation
#18
Elahe Gozali, Reza Safdari, Malihe Sadeghi, Marjan Ghazi Saeidi, Sharareh R Niakan Kalhori, Farahnaz Noroozinia, Zahra Zare Fazlollahi, Bahlol Rahimi
Introduction: Telepathology is a subdiscipline of telemedicine. It has opened new horizons to pathology, especially to the field of organizing consultations. This study aims to determine the capabilities and equipment required for the implementation of telepathology from the viewpoints of managers, IT professionals, and pathologists of the hospitals of West Azerbaijan, Iran. Methods: This is a descriptive-analytical study conducted as a cross-sectional study in 2015...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29416912/commentary-improving-the-efficiency-of-the-ova-and-parasite-examination-using-cloud-based-image-analysis
#19
Daniel D Rhoads
No abstract text is available yet for this article.
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29416911/application-of-text-information-extraction-system-for-real-time-cancer-case-identification-in-an-integrated-healthcare-organization
#20
Fagen Xie, Janet Lee, Corrine E Munoz-Plaza, Erin E Hahn, Wansu Chen
Background: Surgical pathology reports (SPR) contain rich clinical diagnosis information. The text information extraction system (TIES) is an end-to-end application leveraging natural language processing technologies and focused on the processing of pathology and/or radiology reports. Methods: We deployed the TIES system and integrated SPRs into the TIES system on a daily basis at Kaiser Permanente Southern California. The breast cancer cases diagnosed in December 2013 from the Cancer Registry (CANREG) were used to validate the performance of the TIES system...
2017: Journal of Pathology Informatics
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