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Journal of Hepato-biliary-pancreatic Sciences

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https://www.readbyqxmd.com/read/28316140/descriptive-review-of-acute-cholecystitis-japan-taiwan-collaborative-epidemiological-study
#1
Masamichi Yokoe, Tadahiro Takada, Tsann-Long Hwang, Itaru Endo, Kohei Akazawa, Fumihiko Miura, Toshihiko Mayumi, Rintaro Mori, Miin-Fu Chen, Yi-Yin Jan, Chen-Guo Ker, Hsiu-Po Wang, Takao Itoi, Harumi Gomi, Seiki Kiriyama, Hiroki Yamaue, Masaru Miyazaki, Masakazu Yamamoto
BACKGROUND AND AIMS: Since the publication of the Tokyo Guidelines (TG13) for the management of acute cholecystitis (AC), multidirectional studies have been published. However epidemiological research about AC with big data was not projected. The aim of this study was to reveal the actual clinical conditions of AC. METHOD: The study was designed as an international multicenter retrospective study of AC in Japan and Taiwan from 2011 to 2013. The factors investigated comprised data related to demographic, history, physical examinations, laboratory and imaging findings...
March 18, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28301088/survival-benefit-of-intravenous-and-intraperitoneal-paclitaxel-with-s-1-in-pancreatic-ductal-adenocarcinoma-patients-with-peritoneal-metastasis-a-retrospective-study-in-a-single-institution
#2
Sohei Satoi, Hiroaki Yanagimoto, Tomohisa Yamamoto, Satoshi Hirooka, So Yamaki, Hisashi Kosaka, Kentaro Inoue, Yuki Hashimoto, Yoichi Matsui, Masanori Kon
PURPOSE: We evaluated the clinical efficacy of intravenous (i.v.) and intraperitoneal (i.p.) paclitaxel (PTX) combined with S-1 in patients with chemotherapy-naïve pancreatic ductal adenocarcinoma (PDAC) with peritoneal metastasis. METHODS: Forty-nine patients were diagnosed with peritoneal metastasis during 2007-2014; 29 received gemcitabine or S-1 based chemo(radio)therapy from 2007-11 (control group), and the remaining 20 received i.v. (50 mg/m(2) ) and i.p...
March 16, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28273395/a-primary-tumor-of-mixed-histological-type-is-a-novel-poor-prognostic-factor-for-patients-undergoing-resection-of-liver-metastasis-from-gastric-cancer
#3
Naoki Ikari, Kiyoaki Taniguchi, Akiko Serizawa, Takuji Yamada, Masakazu Yamamoto, Toru Furukawa
BACKGROUND: Surgical resection can be an option for the treatment of metastatic liver tumors originating from gastric cancer; however, its prognostic impact is controversial. The aim of this study was to identify prognostic factors in patients with surgical resection of liver metastasis from gastric cancer. METHODS: We retrospectively analyzed the clinicopathological features of 38 consecutive patients undergoing hepatectomy for metastatic tumors from gastric cancer in our institution between 1990 and 2014...
March 8, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28258614/safety-related-outcomes-of-the-japanese-society-of-hepato-biliary-pancreatic-surgery-board-certification-system-for-expert-surgeons
#4
Takehito Otsubo, Shinjiro Kobayashi, Keiji Sano, Takayuki Misawa, Takehiro Ota, Satoshi Katagiri, Katsuhiko Yanaga, Hiroki Yamaue, Norihiro Kokudo, Michiaki Unno, Jiro Fujimoto, Fumihiko Miura, Masaru Miyazaki, Masakazu Yamamoto
PURPOSE: We investigated safety-related outcomes of HBP surgeries performed after establishment of the Japanese Society of Hepato-Biliary-Pancreatic Surgery board certification system for expert surgeons. METHODS: We analyzed post-HBP surgery mortality data obtained from annual safety reports provided by board-certified training institutions between 2012 and 2015. RESULTS: The 90-day mortality rate for the 53,929 high-level HBP surgeries performed at board-certified training institutions was 1...
March 3, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28251830/disparities-in-the-management-and-prophylaxis-of-surgical-site-infection-and-pancreatic-fistula-after-pancreatoduodenectomy
#5
Francisco Igor B Macedo, Mia Mowzoon, Janak Parikh, Sandeep A Sathyanarayana, Michael J Jacobs
BACKGROUND: Pancreatoduodenectomy (PD) carries a high morbidity. Over time, pancreatic surgeons have altered their perioperative management in efforts to reduce morbidity rates, thereby creating major technical and management variations. We aim to evaluate the practice patterns of hepato-pancreato-biliary (HPB) surgeons across multiple regions worldwide. METHODS: Between May and August 2015, an anonymous 25-item survey questionnaire was electronically distributed to IHPBA (International Hepato-Pancreato-Biliary Association) members regarding practice patterns and perioperative care of patients undergoing PD...
March 2, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28196311/an-opportunity-in-difficulty-japan-korea-taiwan-expert-delphi-consensus-on-surgical-difficulty-during-laparoscopic-cholecystectomy
#6
Yukio Iwashita, Taizo Hibi, Tetsuji Ohyama, Goro Honda, Masahiro Yoshida, Fumihiko Miura, Tadahiro Takada, Ho-Seong Han, Tsann-Long Hwang, Satoshi Shinya, Kenji Suzuki, Akiko Umezawa, Yoo-Seok Yoon, In-Seok Choi, Wayne Shih-Wei Huang, Kuo-Hsin Chen, Manabu Watanabe, Yuta Abe, Takeyuki Misawa, Yuichi Nagakawa, Dong-Sup Yoon, Jin-Young Jang, Hee Chul Yu, Keun Soo Ahn, Song Cheol Kim, In Sang Song, Ji Hoon Kim, Sung-Su Yun, Seong Ho Choi, Yi-Yin Jan, Yan-Shen Shan, Chen-Guo Ker, De-Chuan Chan, Cheng-Chung Wu, King-Teh Lee, Naoyuki Toyota, Ryota Higuchi, Yoshiharu Nakamura, Yoshiaki Mizuguchi, Yutaka Takeda, Masahiro Ito, Shinji Norimizu, Shigetoshi Yamada, Naoki Matsumura, Junichi Shindoh, Hiroki Sunagawa, Takeshi Gocho, Hiroshi Hasegawa, Toshiki Rikiyama, Naohiro Sata, Nobuyasu Kano, Seigo Kitano, Hiromi Tokumura, Yuichi Yamashita, Goro Watanabe, Kunitoshi Nakagawa, Taizo Kimura, Tatsuo Yamakawa, Go Wakabayashi, Rintaro Mori, Itaru Endo, Masaru Miyazaki, Masakazu Yamamoto
BACKGROUND: We previously identified 25 intraoperative findings during laparoscopic cholecystectomy (LC) as potential indicators of surgical difficulty per nominal group technique. This study aimed to build a consensus among expert LC surgeons on the impact of each item on surgical difficulty. METHODS: Surgeons from Japan, Korea, and Taiwan (n = 554) participated in a Delphi process and graded the 25 items on a seven-stage scale (range, 0-6). Consensus was defined as (i) the interquartile range (IQR) of overall responses ≤2 and (ii) ≥66% of the responses concentrated within a median ± 1 after stratification by workplace and LC experience level...
February 14, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28196310/gemcitabine-cisplatin-versus-gemcitabine-oxaliplatin-doublet-chemotherapy-in-advanced-gallbladder-cancers-a-match-pair-analysis
#7
Anant Ramaswamy, Vikas Ostwal, Rakesh Pinniti, Sadhana Kannan, Prabhat Bhargava, Chaitali Nashikkar, Jimmy Mirani, Shripad Banavali
BACKGROUND: Gemcitabine-cisplatin (GC) and gemcitabine-oxaliplatin (GO) are the most commonly used regimens in advanced gallbladder cancer (GBC). METHODS: The data of patients with advanced GBC, treated between January 2013 and June 2015 were retrieved. A 1:1 matching without replacement was performed by using nearest neighbour matching method. RESULTS: 326 patients (163 GC and 163 GO), were matched 1:1 by age and gender. The response rates for GC and GO were 31...
February 14, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28196308/risk-factors-of-serious-postoperative-complications-after-pancreaticoduodenectomy-and-risk-calculators-for-predicting-postoperative-complications-a-nationwide-study-of-17-564-patients-in-japan
#8
Shuichi Aoki, Hiroaki Miyata, Mitsukazu Gotoh, Fuyuhiko Motoi, Hiraku Kumamaru, Hiroyuki Konno, Go Wakabayashi, Yoshihiro Kakeji, Masaki Mori, Yasuyuki Seto, Michiaki Unno
BACKGROUND: The morbidity rate after pancreaticoduodenectomy remains high. The objectives of this retrospective cohort study were to clarify the risk factors associated with serious morbidity (Clavien-Dindo classification grades IV-V), and create complication risk calculators using the Japanese National Clinical Database. METHODS: Between 2011 and 2012, data from 17564 patients who underwent pancreaticoduodenectomy at 1311 institutions in Japan were recorded in this database...
February 14, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28160422/survival-benefit-of-hepatic-resection-for-hepatocellular-carcinoma-beyond-the-barcelona-clinic-liver-cancer-classification
#9
Kenei Furukawa, Hiroaki Shiba, Takashi Horiuchi, Yoshihiro Shirai, Koichiro Haruki, Yuki Fujiwara, Taro Sakamoto, Takeshi Gocho, Katsuhiko Yanaga
BACKGROUND: The Barcelona Clinic Liver Cancer (BCLC) classification is the most widely used staging system for hepatocellular carcinoma (HCC), but its prognostic ability in patients after resection has not been yet validated. The aim of this study was to evaluate the BCLC classification among patients after resection. METHODS: The subjects were 196 patients who underwent hepatic resection for HCC between April 2003 and December 2014 at Jikei University Hospital...
February 3, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28111910/japanese-clinical-practice-guidelines-for-congenital-biliary-dilatation
#10
LETTER
Hiroki Ishibashi, Mitsuo Shimada, Terumi Kamisawa, Hideki Fujii, Yoshinori Hamada, Masayuki Kubota, Naoto Urushihara, Itaru Endo, Masaki Nio, Tomoaki Taguchi, Hisami Ando
Until now, there have been no practical clinical guidelines for congenital biliary dilatation (CBD). In this review article, the Japanese Study Group on Congenital Biliary Dilatation (JSCBD) propose to establish clinical practice guidelines for CBD. Because the evidence-based literature is relatively small, we decided to create guidelines based on the consensus of experts, using the medical literature for reference. A total of 20 clinical questions (CQs) were considered by the members of the editorial committee responsible for the guidelines...
January 22, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28107613/variant-outcomes-of-liver-transplantation-for-hepatitis-c-virus-patients-in-different-age-categories-impact-of-the-meld-score
#11
Zhenhua Hu, Jie Zhou, Zhiwei Li, Jie Xiang, Qijun Zhang, Sheng Yan, Jian Wu, Min Zhang, Weilin Wang, Shusen Zheng
BACKGROUND: Whether the introduction of model for end-stage liver disease (MELD) has an effect on transplant outcome for different age categories remain unclear. METHODS: We analyzed 49,762 adult hepatitis C virus (HCV) candidates through 1995-01-01 to 2012-12-31 from the Scientific Registry of Transplant Recipients. Patients were divided into four age categories (18-34 yr, 35-49 yr, 60-64 yr, ≥65 yr) in the pre-MELD era and MELD era respectively. RESULTS: Waiting list dropouts have decreased in the MELD era for all categories...
January 20, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28103424/no-negative-impact-of-serum-igg4-levels-on-clinical-outcome-in-435-patients-with-primary-sclerosing-cholangitis-from-japan
#12
Atsushi Tanaka, Susumu Tazuma, Takahiro Nakazawa, Hiroyuki Isayama, Toshio Tsuyuguchi, Kazuo Inui, Hajime Takikawa
BACKGROUND: Several studies have demonstrated that elevated serum IgG4 levels are associated with poor outcomes of primary sclerosing cholangitis (PSC), but the impact of serum IgG4 levels on PSC remains controversial. In this study, we aimed to determine prognostic factors of patients with PSC and to investigate the association between serum IgG4 levels and the clinical features and prognosis of PSC in a Japanese cohort. METHODS: We retrospectively analyzed follow-up data for 435 patients with PSC (UMIN000018438)...
January 19, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28103418/three-hundred-and-sixty-eight-consecutive-pancreaticoduodenetomies-with-zero-mortality
#13
Seiji Oguro, Jiro Yoshimoto, Hiroshi Imamura, Yoichi Ishizaki, Seiji Kawasaki
BACKGROUND: Only a limited number of reports have documented zero mortality in consecutive pancreaticoduodenetomy series. The aim of this study is to review and verify our management aiming to eliminate mortality after pancreaticoduodenetomy. METHODS: Three hundred and sixty-eight consecutive patients undergoing pancreaticoduodenetomy between 2002 and 2015 were retrospectively reviewed. During this period, in order to enhance the safety of pancreaticoduodenetomy, we have used a consistent strategy consisting of early ligation of the inferior pancreatoduodenal artery, mucosal sutureless pancreaticojejunostomy combined with external pancreatic duct stenting, conditional two-stage pancreaticojejunostomy, jejunal decompression using tube jejunostomy, application of an omental flap to cover the stump of the gastroduodenal artery, and careful postoperative drain management...
January 19, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28026137/the-right-way-is-not-always-popular-comparison-of-surgeons-perceptions-during-laparoscopic-cholecystectomy-for-acute-cholecystitis-among-experts-from-japan-korea-and-taiwan
#14
Taizo Hibi, Yukio Iwashita, Tetsuji Ohyama, Goro Honda, Masahiro Yoshida, Tadahiro Takada, Ho-Seong Han, Tsann-Long Hwang, Satoshi Shinya, Kenji Suzuki, Akiko Umezawa, Yoo-Seok Yoon, In-Seok Choi, Wayne Shih-Wei Huang, Kuo-Hsin Chen, Fumihiko Miura, Manabu Watanabe, Yuta Abe, Takeyuki Misawa, Yuichi Nagakawa, Dong-Sup Yoon, Jin-Young Jang, Hee Chul Yu, Keun Soo Ahn, Song Cheol Kim, In Sang Song, Ji Hoon Kim, Sung Su Yun, Seong Ho Choi, Yi-Yin Jan, Shyr-Ming Sheen-Chen, Yan-Shen Shan, Chen-Guo Ker, De-Chuan Chan, Cheng-Chung Wu, Naoyuki Toyota, Ryota Higuchi, Yoshiharu Nakamura, Yoshiaki Mizuguchi, Yutaka Takeda, Masahiro Ito, Shinji Norimizu, Shigetoshi Yamada, Naoki Matsumura, Junichi Shindoh, Hiroki Sunagawa, Takeshi Gocho, Hiroshi Hasegawa, Toshiki Rikiyama, Naohiro Sata, Nobuyasu Kano, Seigo Kitano, Hiromi Tokumura, Yuichi Yamashita, Goro Watanabe, Kunitoshi Nakagawa, Taizo Kimura, Tatsuo Yamakawa, Go Wakabayashi, Itaru Endo, Masaru Miyazaki, Masakazu Yamamoto
BACKGROUND: Generally, surgeons' perceptions of surgical safety are based on experience and institutional policy. Our recent pilot survey demonstrated that the acceptable duration of surgery and criteria for open conversion during laparoscopic cholecystectomy (LC) vary among workplaces. METHODS: A web-based survey was distributed to 554 expert LC surgeons in Japan, Korea, and Taiwan. The questionnaire covered LC experience, safety measures and recognition of landmarks, decision-making regarding conversion to open/partial cholecystectomy and the implications of this decision...
December 26, 2016: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28297162/issue-information-ifa
#15
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28181419/anterior-approach-for-right-hepatectomy-with-hanging-maneuver-for%C3%A2-hepatocellular-carcinoma-a-multi-institutional-propensity-score-matching-study
#16
Toru Beppu, Katsunori Imai, Koji Okuda, Susumu Eguchi, Kenji Kitahara, Nobuhiko Taniai, Shinichi Ueno, Ken Shirabe, Masayuki Ohta, Kazuhiro Kondo, Atsushi Nanashima, Tomoaki Noritomi, Masayuki Shiraishi, Yuko Takami, Kohji Okamoto, Ken Kikuchi, Hideo Baba, Hikaru Fujioka
BACKGROUND: This multi-institutional study aimed to assess the benefits of anterior approach for right hepatectomy with hanging maneuver (ARH-HM) for hepatocellular carcinoma (HCC) compared with conventional right hepatectomy (CRH). METHODS: From January 2000 to December 2012, 306 patients with HCC ≥5 cm were divided into two groups: ARH-HM (n = 104) and CRH (n = 202). RESULTS: After one-to-one propensity score-matched analysis, 72 ARH-HM and 72 CRH patients presented comparable background factors...
March 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28064462/value-of-apparent-diffusion-coefficient-prior-to-neoadjuvant-therapy-is-a-predictor-of-histologic-response-in-patients-with-borderline-resectable-pancreatic-carcinoma
#17
Ken-Ichi Okada, Seiko Hirono, Manabu Kawai, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Fumiyoshi Kojima, Hiroki Yamaue
BACKGROUND: The parameters to predict histological response to neoadjuvant therapy remain controversial in borderline resectable pancreatic carcinoma (BRPC). METHODS: Twenty-four patients who underwent diffusion-weighted magnetic resonance imaging (DW-MRI) prior to expected neoadjuvant chemo/chemoradiotherapy and surgery were reviewed retrospectively. Analyses for correlation between percent tumor cell destruction and the following was performed to investigate the parameter and cut off value: tumor size, whole tumor apparent diffusion coefficient (ADC) value of DW-MRI, maximum standardized uptake value of (18) F-fluorodeoxyglucose positron emission tomography, carbohydrate antigen 19-9, and their change ratios...
March 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28064441/analysis-of-the-origin-of-anaplastic-pancreatic-cancer-and-the-mechanism-of-its-dedifferentiation
#18
Kotaro Miura, Kenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Kohei Nishio, Naoki Kametani, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: We researched the origin and progression of anaplastic pancreatic cancer (APC) from the viewpoints of cell lineage, epithelial-mesenchymal transition (EMT) and cancer stem-like cells (CSC). METHODS: Using specimens from patients with APC and differentiated pancreatic ductal adenocarcinoma (PDAC), expression of sex-determining region Y-box 9 (SOX9), E-cadherin, vimentin, ZEB1, Snail, N-cadherin, CD24 and CD44 was estimated using immunohistochemistry. RESULTS: Almost all cases were positive for SOX9 expression...
March 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28054751/prevention-of-pancreatic-fistula-using-polyethylene-glycolic-acid-mesh-reinforcement-around-pancreatojejunostomy-the-propensity-score-matched-analysis
#19
Jae Seung Kang, Youngmin Han, Hongbeom Kim, Wooil Kwon, Sun-Whe Kim, Jin-Young Jang
BACKGROUND: Several small-scale studies have shown that wrapping polyethylene glycolic acid (PGA) mesh around the anastomotic site reinforced pancreaticojejunostomy following pancreatoduodenectomy (PD) with favorable outcomes. This study investigated the efficacy of PGA mesh for reducing postoperative pancreatic fistula (POPF) and evaluated other risk factors for POPF. METHODS: This study enrolled 464 consecutive patients who underwent PD performed by one surgeon between 2006 and 2015, including a PGA group of 281 patients (60...
March 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28054747/bilobar-versus-unilobar-multiple-colorectal-liver-metastases-a-propensity-score-analysis-of-surgical-outcomes-and-recurrence-patterns
#20
Yasuyuki Fukami, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Takamasa Takahashi, Shunsuke Onoe, Masahito Uji, Kenji Wakai
BACKGROUND: Bilobar multiple colorectal liver metastases (MCLM) are often considered incurable or associated with a poor prognosis even after R0 resection. This study was designed to compare the long-term outcomes and recurrence patterns after one-stage resection in patients with bilobar versus unilobar MCLM. METHODS: The records of patients undergoing parenchymal-sparing intent hepatectomy between 1994 and 2015 were reviewed. Survival and recurrence patterns were analyzed by propensity score matching...
March 2017: Journal of Hepato-biliary-pancreatic Sciences
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