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Journal of Hepato-biliary-pancreatic Sciences

Keiko Sasaki, Simon Tan
No abstract text is available yet for this article.
May 22, 2018: Journal of Hepato-biliary-pancreatic Sciences
Koki Maeda, Goro Honda, Masanao Kurata, Yuki Homma, Manami Doi, Jun Yamamoto, Yusuke Ome
BACKGROUND: In our process of standardizing laparoscopic right hemihepatectomy (Lap-RH), we found several advantages of the laparoscopic caudate lobe first approach by utilizing a unique laparoscopic caudodorsal view. METHODS: Between April 2012 and October 2017, 21 patients underwent pure Lap-RH at our hospital. The mean patient age was 62 years (range, 36-75 years), and there were more male than female patients (66.7%). Of 21 patients, 11 had hepatocellular carcinoma, 8 had metastatic tumor, and the other 2 had focal nodular hyperplasia and refractory liver abscess...
May 17, 2018: Journal of Hepato-biliary-pancreatic Sciences
Kiyotsugu Iede, Akimasa Nakao, Kenji Oshima, Ryota Suzuki, Hironori Yamada, Yukiko Oshima, Hironobu Kobayashi, Yasunori Kimura
PURPOSE: Early ligation of the inferior pancreatoduodenal artery has been advocated to reduce blood loss during pancreatoduodenectomy. However, the impact of early ligation of the dorsal pancreatic artery (DPA) remains unclear. This study was performed to investigate the clinical implications of early ligation of the DPA. METHODS: From October 2014 to April 2017, 34 consecutive patients underwent pancreatoduodenectomy using a mesenteric approach. The patients were divided into the early DPA ligation group (n = 15) and late DPA ligation group (n = 19)...
May 10, 2018: Journal of Hepato-biliary-pancreatic Sciences
Chien-Hui Wu, Te-Wei Ho, Jin-Ming Wu, Ting-Chun Kuo, Ching-Yao Yang, Fei-Pei Lai, Yu-Wen Tien
BACKGROUND: The rate of preoperative biliary drainage for pancreaticoduodenectomy has been increasing despite most recent evidence that favors avoiding it. Only a few studies have focused on late surgical complications - biliary stricture after pancreaticoduodenectomy and have produced only inconclusive results. We evaluate the role of preoperative biliary drainage in formation of biliary stricture after pancreaticoduodenectomy. METHODS: The Taiwan National Health Insurance Program is a mandatory health care plan covers nearly the entire population of 23-million in this country...
May 7, 2018: Journal of Hepato-biliary-pancreatic Sciences
Manabu Kawai, Satoshi Hirano, Hiroki Yamaue
"Artery-first approach" for pancreaticoduodenectomy (PD) has gained recognition and has spread worldwide since Weitz et al. first used the term in 2010.1 , Division of the pancreatic head from the superior mesenteric artery (SMA) is traditionally performed during the final step of PD. Artery-first approach, however, has both oncological impact and better surgical technique; resectability can be determined early before committing an irreversible step during PD and blood loss may be reduced by early closure of blood flow into the pancreatic head...
April 17, 2018: Journal of Hepato-biliary-pancreatic Sciences
Seiki Tashiro, Hidenori Miyake, Kazuhito Rokutan
Heat shock proteins (HSPs) are rapidly synthesized into cells in response to various types of physical or chemical insults and induce potent resistance to the stressors. A stress-inducible HSP70 is not expressed in normal conditions, but once HSP70 is excessively induced under various environmental stresses, HSP70-expressing cells can survive even under lethal conditions. In this review, we focused on the potential role of HSPs particularly HSP70 in liver surgery. A non-toxic HSP70 inducer, geranylgeranylacetone (GGA), has been introduced to exert a potent cytoprotective action against liver injury after ischemia/reperfusion, massive hepatectomy and liver transplantation in animal experiments...
April 15, 2018: Journal of Hepato-biliary-pancreatic Sciences
Tomoaki Yoh, Etsuro Hatano, Satoru Seo, Hiroaki Terajima, Yoichiro Uchida, Kojiro Taura, Kentaro Yasuchika, Shinji Uemoto
BACKGROUND: Imaging study cannot identify patients with potential low-risk for LN metastasis in intrahepatic cholangiocarcinoma (ICC). The purpose of this study was to identify a low-risk group for lymph node (LN) metastasis in ICC using preoperatively available factors. METHODS: Data from 127 consecutive patients, who underwent curative intent surgery for ICC at Kyoto University Hospital and Kitano Hospital between 2002 and 2016, were retrospectively analyzed. By using only preoperative data, multiple linear regression model for predicting LN metastasis was developed...
April 14, 2018: Journal of Hepato-biliary-pancreatic Sciences
Takeshi Saito, Keita Terui, Tetsuya Mitsunaga, Mitsuyuki Nakata, Shugo Komatsu, Hideo Yoshida
BACKGROUND: Among biliary atresia (BA) patients undergoing revision following failed portoenterostomy, long-term native liver survival (NLS), physical condition, and indications for revision were explored. METHODS: From 1977-2015, 33 of 95 BA patients (35%) at our institution underwent revision. Ten- and 20-year NLS rates (NLSRs) and biochemical statuses of 20-year-old native liver survivors were compared between post-portoenterostomy BA patients with and without history of revision...
March 25, 2018: Journal of Hepato-biliary-pancreatic Sciences
Hiroaki Shimizu, Takao Itoi, Keiji Sano
This review traces the historical development of percutaneous transhepatic biliary interventions for the management of biliary disorder. Furthermore, several landmark achievements in the process of the establishment of percutaneous transhepatic cholangiography (PTC) and percutaneous transhepatic biliary drainage (PTBD) are discussed.Visualization of the biliary tract by puncturing the gallbladder percutaneously was first reported by Burckhardt and Muller in 1921 [1]. Thereafter, Huard and Du-Xuan-Hop succeeded in PTC by puncture of the intrahepatic bile duct in two patients with obstructive jaundice in 1937 [2]...
March 24, 2018: Journal of Hepato-biliary-pancreatic Sciences
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Journal of Hepato-biliary-pancreatic Sciences
Junji Furuse, Junji Shibahara, Masanori Sugiyama
While surgery currently remains the only potentially curative treatment available for pancreatic cancer, only 20% to 30% of patients have resectable disease at diagnosis. Recently, with the introduction of intensive chemotherapy regimens such as oxaliplatin, irinotecan, fluorouracil plus leucovorin (FOLFIRINOX) and gemcitabine plus nab-paclitaxel, for the treatment of unresectable pancreatic cancer, the antitumor activity and overall survival in patients with pancreatic cancer have dramatically improved. These advances in intensive chemotherapy have led to the possibility of conversion of unresectable disease to resectable disease, and it has been reported that more than 20% of pancreatic cancer patients with unresectable locally advanced disease at diagnosis undergo successful conversion surgery after FOLFIRINOX therapy...
May 2018: Journal of Hepato-biliary-pancreatic Sciences
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Journal of Hepato-biliary-pancreatic Sciences
Sang-Hyun Kang, Shin Hwang, Young-Joo Lee, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Sung-Gyu Lee
BACKGROUND: Several important changes were made to the 8th edition of the American Joint Committee on Cancer (AJCC) tumor staging system for intrahepatic cholangiocarcinoma (ICC). We assessed the prognostic impact of this new tumor staging system compared to the 7th edition. METHODS: A retrospective single-institution study was performed with 626 patients who underwent R0 resection for ICC over 20-year period. RESULTS: Anatomical resection and concurrent bile duct resection were performed in 571 (91...
April 2018: Journal of Hepato-biliary-pancreatic Sciences
Kensuke Kubota, Terumi Kamisawa, Kenji Hirano, Yoshiki Hirooka, Kazushige Uchida, Tsukasa Ikeura, Hideyuki Shiomi, Hirotaka Ohara, Kyoko Shimizu, Norikazu Arakura, Atsushi Kanno, Junichi Sakagami, Takao Itoi, Tetsuhide Ito, Toshiharu Ueki, Takayoshi Nishino, Kazuo Inui, Nobumasa Mizuno, Hitoshi Yoshida, Masanori Sugiyama, Eisuke Iwasaki, Atsushi Irisawa, Kazuichi Okazaki, Shigeyuki Kawa, Toru Shimosegawa, Yoshifumi Takeyama, Tsutomu Chiba
BACKGROUND: Sporadic autoimmune pancreatitis (AIP) cases showing remission without steroid treatment have been reported, however, the clinical course of these patients has not been clarified. This study sought to clarify the clinical course in AIP patients with hesitation for steroid treatment. METHODS: We collected clinical data for AIP patients from high-volume centers in Japan. Data for AIP patients with and those without steroid treatment (steroid treatment vs...
April 2018: Journal of Hepato-biliary-pancreatic Sciences
Shinjiro Kobayashi, Kohei Segami, Hiroyuki Hoshino, Kazunari Nakahara, Masafumi Katayama, Satoshi Koizumi, Takehito Otsubo
BACKGROUND: Enhanced recovery after surgery (ERAS) protocols are beneficial for pancreatoduodenectomy (PD). Our aim was to evaluate risk factors associated with ERAS protocol failure after PD. METHODS: Clinical variables of 187 patients managed using ERAS protocols between April 2011 and April 2017, including non-early recovery (non-ER) patients, with complications or requiring a hospital stay ≥15 days, and early recovery (ER) patients, were compared. A physical aging (PA) score was devised to predict postoperative risks...
April 2018: Journal of Hepato-biliary-pancreatic Sciences
Jun Sakata, Tomoki Ebata, Toshifumi Wakai
No abstract text is available yet for this article.
April 2018: Journal of Hepato-biliary-pancreatic Sciences
Michele Pisano, Fabio Cesare Campanile
No abstract text is available yet for this article.
March 2018: Journal of Hepato-biliary-pancreatic Sciences
Akihisa Kato, Itaru Naitoh, Katsuyuki Miyabe, Kazuki Hayashi, Hiromu Kondo, Michihiro Yoshida, Hiroyuki Kato, Toshiya Kuno, Satoru Takahashi, Takashi Joh
BACKGROUND: Fluorescence in situ hybridization (FISH) of cytology specimens has been used to diagnose biliary strictures. However, the usefulness of FISH for differentiating between cholangiocarcinoma (CCA) and IgG4-related sclerosing cholangitis (IgG4-SC) has not been evaluated in forceps biopsy specimens. METHODS: We retrospectively reviewed 74 specimens obtained by transpapillary forceps biopsy between 2008 and 2015 from 49 consecutive patients with CCA and 25 with IgG4-SC...
March 2018: Journal of Hepato-biliary-pancreatic Sciences
Itaru Endo, Masamichi Yokoe
No abstract text is available yet for this article.
March 2018: Journal of Hepato-biliary-pancreatic Sciences
Lili Zhu, Lei Wang, Fei Cao, Peng Liu, Haidong Bao, Yumei Yan, Xin Dong, Dong Wang, Zhongyu Wang, Peng Gong
BACKGROUND: The purpose of the present study was to investigate the effect and potential mechanism of chlorogenic acid (CA) on liver injury induced by cholestasis in a rat model of bile duct ligation (BDL). METHODS: Rats received vehicle or CA (20, 50, or 100 mg/kg per day) orally for 3 days. On the 4th day, the rats underwent sham or BDL surgery, and were orally administrated vehicle or CA for 3 or 7 days. mRNA and protein expression levels were evaluated by qRT-PCR and western blot...
March 2018: Journal of Hepato-biliary-pancreatic Sciences
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