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https://www.readbyqxmd.com/read/29610596/catecholaminergic-polymorphic-ventricular-tachycardia-looking-to-the-future
#1
Andreea Elena Velcea, Calin Siliste, Dragos Vinereanu
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inheritable cardiac disorder, characterized by polymorphic ventricular tachycardia (PVT) or bidirectional ventricular tachycardia, triggered by adrenergic stress, and manifested most frequently as syncope or sudden cardiac death. The disease has a heterogeneous genetic basis, with mutations in the genes encoding the ryanodine and calsequestrin channels accounting for the majority of cases. The diagnosis of CPVT is established in individuals with polymorphic ventricular premature beats, PVT or bidirectional ventricular tachycardia documented during exercise or adrenergic stress, who have a structurally normal heart and normal resting ECG...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610595/the-basic-steps-of-evolution-of-brain-surgery
#2
Alexandrina Nikova, Theodossios Birbilis
Objective and conclusion: Neurosurgery is probably the most constantly developing specialty of all times. Its dimension is enormous and its history, Ancient. The evolution of neurosurgery from the Mayan and Egyptian periods to the Renaissance and the 21st century was the result of many physicians and patients whose experiences lead to the revolution of modernization. Today, the field of neurosurgery is continuously expanding, aiming to introduce knowledge and technologies that could provide a new futuristic wave of medicine...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610594/tyrosine-kinase-inhibitors-treatment-in-advanced-malignant-melanoma
#3
Andrei Popescu, Rodica Maricela Anghel
Objective: To put in perspective recent advances in the treatment of malignant melanoma with novel tyrosine-kinase inhibitors. Methods: We reviewed the largest trials that support the treatment with tyrosine-kinase inhibitors (TKIs) in cutaneous malignant melanoma, the base of the current guideline recommendations. Conclusions: Mitogen-activated protein-kinase (MAPK) pathway inhibition via modern TKIs is a major breakthrough in the treatment of melanoma, with a very high benefit for patients with disease harboring BRAF-gene mutations, in terms of rates of response and survival...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610593/immunological-evaluation-of-surgical-stress-in-liver-resections
#4
Alexandru Munteanu, Gabriel Samasca, Iulia Lupan, Cornel Iancu
Surgery has its origins in caring for patients suffering from injury or infection. In the last decade, a huge amount of published data has been describing a wide range of conditions resulting from trauma or infection, from minor, local reactions to a surgical operation and leading to a systemic stress response, systemic inflammatory response and finally to multiple organ failure. Our aim was to highlight the main immunological aspects of liver resections. There are many types of liver resections, ranging from small, isolated resections for benign diseases (e...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610592/predominant-upper-limb-chronic-demyelinating-polyneuropathy-associated-with-hbv-infection
#5
Ioan-Cristian Lupescu, Adriana Octaviana Dulamea
Chronic inflammatory demyelinating polyneuropathy is an acquired, presumably immune-mediated peripheral neuropathy, characterized by symmetric sensory-motor involvement. Although most often idiopathic, it has been described in association with several disorders, sometimes improving under treatment. We present the case of a 57-year-old male who was admitted to hospital for paresthesias and muscle weakness affecting both upper limbs, initially only the hands, but with worsening and ascending progression during the last three years...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610591/does-phantom-tumor-really-exist
#6
Dan-Nicolae Tesloianu, Mihaela Chioarta, Dana Corduneanu, Andreea-Mihaela Ignat, Antoniu Octavian Petris, Anda Tesloianu
Localized interlobar effusion in congestive heart failure (known as phantom tumor or vanishing tumor of the lung) is an uncommon entity. We report a case of a 61-year-old man who presented to the Emergency Departament with a two week history of dyspnoea, palpitations, dry cough and intermitent anterior chest pain. A posteroanterior chest radiography showed a nodular mass in the medium third of the right hemithorax suggestive of a pulmonary tumor. With this supposition of diagnosis, the patient was admitted to the Pneumology Departament for further investigations...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610590/effects-of-appropriate-nutrition-training-in-small-groups-on-laboratory-parameters-in-hemodialysis-patients-from-iran
#7
Nader Aghakhani, Seyyedeh Leila Hoseini, Kourosh Kamali, Davoud Vahabzadeh
Introduction: Adherence to appropriate nutrition and fluid intake is one of the essential parts of chronic renal failure treatment for achieving the desirable results among the patients with hemodialysis. Among various training methods, the "small groups' method", as an advanced method, can be performed by nurses in achieving desirable therapeutic results. The present study was aimed to investigate the effect of appropriate nutrition training in small groups on laboratory parameters in hemodialysis patients...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610589/a-statistical-assessment-of-information-knowledge-and-attitudes-of-medical-students-regarding-contraception-use
#8
Anca A Simionescu, Alexandra Horobet, Lucian Belascu
Objective: To evaluate how contraception use is linked to information, knowledge and attitudes towards family planning and contraception of medical students. Methods: This is a voluntary cross-sectional study using an anonymous questionnaire applied to 62 medical students. The questionnaire had the following main structure: characteristics of the studied population, information on contraception, knowledge about contraception methods, attitudes regarding family planning and contraception, and contraception use...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610588/plasma-prolactin-and-total-lipid-levels-and-subsequent-risk-of-breast-cancer-in-pre-and-postmenopausal-women-experience-from-an-indian-rural-centre
#9
Nidhi Gupta, Gautam Mendiratta, Rikki Singal, N S Sharma
Aims and objectives: 1) To analyze serum lipid and prolactin levels in breast cancer patients and normal subjects; 2) to correlate those levels with risk and prognostic factors. Material and Methods: The present study was performed in the Department of Surgery, MMIMSR, Mullana, Ambala, from 2013 to 2014, at a rural centre. The study group comprised 40 patients with carcinoma of the breast who underwent surgery and the control group included 10 patients who underwent surgery for reasons other than carcinoma of the breast...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610587/high-resolution-melting-curve-analysis-for-rapid-detection-of-streptomycin-and-ethambutol-resistance-in-mycobacterium-tuberculosis
#10
Faranak Rezaei, Mehri Haeili, Abbasali Imani Fooladi, Mohammad Mehdi Feizabadi
Objectives: Development of molecular techniques for rapid detection of drug resistant tuberculosis allows for the prompt initiation of appropriate anti-TB treatment. We aimed to assess high-resolution melting (HRM) analysis for the detection of rpsL, rrs and embB mutations to identify streptomycin and ethambutol resistance in Mycobacterium tuberculosis. Material and Methods: A total of 76 clinical isolates of M. tuberculosis including 25 SM-R, 21 EB-R and 30 drug susceptible - determined by the proportion method of drug susceptibility testing (DST) - were analyzed by HRM analysis, and the results were confirmed using DNA sequencing...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610586/analysis-of-interleukin-17-mrna-level-in-the-urinary-cells-of-kidney-transplant-recipients-with-stable-function
#11
Morteza Bagheri, Ali Taghizadeh-Afshari, Saeed Abkhiz, Isa Abdi-Rad, Mohammadreza Mohammadi-Fallah, Mansour Alizadeh, Saeed Sadeghzadeh
Objectives: Kidney transplantation supports patients with end-stage kidney diseases. Many factors control the allograft function in kidney transplant recipients. Interleukin-17 (IL-17) can be used as a non-invasive diagnostic biomarker of rejection. The aim of this study was to evaluate the expression of IL-17 mRNA in urinary cells of kidney transplant recipients with stable function. Material and Methods: A total of 40 renal transplant recipients who were admitted for surgery and 30 healthy controls were enrolled in the study...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610585/pulmonary-diffusion-capacity-for-carbon-monoxide-dlco-in-indonesian-patients-with-end-stage-renal-disease
#12
Taruli Loura Batubara, Faisal Yunus, Ratnawati, Yassir, Fariz Nurwidya
Objectives: End-stage renal disease affects all systems in human including the respiratory system. This study aimed to discover the lung diffusion capacity of carbon monoxide (DLCO) in chronic hemodialysis patients and to establish its relation to several demographic and clinical factors as well as spirometry parameters. Material and Methods: This was a cross-sectional study among chronic hemodialysis patients aged .18 years, clinically stable in the last four weeks, without prior history of lung and cardiac disorder...
December 2017: Mædica
https://www.readbyqxmd.com/read/29610584/justice-came-to-hypertension-or-did-it
#13
EDITORIAL
Mircea Cinteza
No abstract text is available yet for this article.
December 2017: Mædica
https://www.readbyqxmd.com/read/29218070/radiographic-evaluation-of-alignment-following-tka-a-systematic-review
#14
Serban Dragosloveanu, Bogdan Cretu, Stefan Cristea, Cristian Stoica, Calin Dragosloveanu
Postoperative assessment is of paramount importance in primary total knee arthroplasty. A thorough postoperative analysis helps the surgeon anticipate any postoperative potential issues and correlate the preoperative planning with the postoperative result, and provides better understanding of the importance of surgical principles of primary total knee arthroplasty. In addition, postoperative analysis helps the surgeon understand surgical errors and improve future outcomes. Standard radiographs, with a known magnification, should be obtained for postoperative total knee arthroplasty evaluation...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218069/down-syndrome-genetics-and-cardiogenetics
#15
Vasilica Plaiasu
During the last years, Down syndrome has been the focus of special attention. Down syndrome is a genetic disorder characterized by distinct physical features and some degree of cognitive disability. Patients with Down syndrome also present many other congenital anomalies. The mapping for phenotypes to specific regions of chromosome 21 permits to identify which genes (or small regions) contribute to the phenotypic features of Down syndrome and thus, to understand its pathogenesis. Mainly there are three cytogenetic forms of Down syndrome: free trisomy 21, mosaic trisomy 21 and robertsonian translocation trisomy 21...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218068/prostheses-used-in-laparoscopic-inguinal-hernia-repair-biocompatibility-postoperative-complications-and-quality-of-life-review-of-the-literature
#16
Alexandra Florina Trandafir, Dorin Eugen Popa, Danut Vasile
INTRODUCTION: There is a continuous concern about meshes used in laparoscopic inguinal hernia repair, which mainly relates to their biocompatibility and ability to decrease postoperative complications and recurrence rate; in other words, efforts are made to find the "ideal" prosthesis. OBJECTIVES: To evaluate different prostheses used in laparoscopic inguinal hernia repair in terms of biocompatibility, postoperative complications, recurrence rate and quality of life, so that all the features could lead us to the "ideal" mesh...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218067/perceived-age-and-life-style-the-specific-contributions-of-seven-factors-involved-in-health-and-beauty
#17
Victor Gabriel Clatici, Daniel Racoceanu, Claude Dalle, Cristiana Voicu, Lucia Tomas-Aragones, Servando E Marron, Uwe Wollina, Simona Fica
OBJECTIVES: The skin is a dynamic, visible organ, showing the most obvious signs of aging. The mechanisms of extrinsic aging, most of them presented in this paper, are currently well known and also the only ones that can be counteracted. Therefore, the transition of this knowledge in the general population is of the most importance, in order to introduce healthy aging strategies, to prevent the development of chronic or malignant diseases and psychological burden related to old age. MATERIALS AND METHODS: A thorough review of the literature has been performed in order to identify the main factors involved in skin health and aging...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218066/arterial-stiffness-and-hypertension-which-comes-first
#18
Monica Ecobici, Claudiu Stoicescu
Arterial hypertension is one of the traditional risk factors involved in the development of cardiovascular events, while arterial stiffness is an independent predictor of cardiovascular disease in patients with hypertension. It seems that the risk factors involved in the pathology of uncontrolled hypertension are similar to those that contribute to the development of arterial stiffness. After evidence showed that arterial stiffness is an independent prognostic factor for the occurrence of cardiovascular events in patients with arterial hypertension, the importance of assessing arterial stiffness was recognized in a document drafted by the European Society of Hypertension in 2007...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218065/acute-myocardial-injury-in-a-child-with-duchenne-muscular-dystrophy-pulse-steroid-therapy
#19
Eliza Cinteza, Claudiu Stoicescu, Niculina Butoianu, Mihaela Balgradean, Alin Nicolescu, Matthias Angrés
Heart implication in Duchenne muscular dystrophy usually is present in the form of dilated cardiomyopathy, manifested as heart failure and arrhythmias. To delay progression, including heart deterioration, prednisone is recommended as preventive treatment. We report the case of an 11-year-old boy diagnosed with Duchenne muscular dystrophy at the age of seven, who was on preventive treatment with oral prednisone (0.75 mg/kg/day) and beta blocker (metoprolol, 1 mg/kg/day). Suddenly, the patient presented acute chest pain, vomiting and sweating...
September 2017: Mædica
https://www.readbyqxmd.com/read/29218064/non-diabetic-hyperglycemia-and-some-of-its-correlates-in-icu-hospitalized-patients-receiving-enteral-nutrition
#20
Mohammad Amin Valizadeh Hasanloei, Zahra Vahdat Shariatpanahi, Davoud Vahabzadeh, Zakaria Vahabzadeh, Leila Nasiri, Ali Shargh
Introduction: Hyperglycemia is a common occurrence in critically ill patients, and its prevalence in patients receiving nutritional support is much higher than in other patients. The non-diabetic form is associated with more undesirable outcomes. This study was performed to determine the prevalence of non-diabetic hyperglycemia and its correlates in patients receiving enteral nutrition. Material and Methods: This cross-sectional study was performed between March and December 2015...
September 2017: Mædica
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