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Journal of Nutrition and Metabolism

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https://www.readbyqxmd.com/read/28097021/downregulation-of-pgc-1%C3%AE-prevents-the-beneficial-effect-of-eet-heme-oxygenase-1-on-mitochondrial-integrity-and-associated-metabolic-function-in-obese-mice
#1
Shailendra P Singh, Lars Bellner, Luca Vanella, Jian Cao, John R Falck, Attallah Kappas, Nader G Abraham
Background/Objectives. Obesity and metabolic syndrome and associated adiposity are a systemic condition characterized by increased mitochondrial dysfunction, inflammation, and inhibition of antioxidant genes, HO-1, and EETs levels. We postulate that EETs attenuate adiposity by stimulating mitochondrial function and induction of HO-1 via activation of PGC-1α in adipose and hepatic tissue. Methods. Cultured murine adipocytes and mice fed a high fat (HF) diet were used to assess the functional relationship among EETs, PGC-1α, HO-1, and mitochondrial signaling using an EET-agonist (EET-A) and PGC-1α-deficient cells and mice using lentiviral PGC-1α(sh)...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28083148/effects-of-exercise-training-under-hyperbaric-oxygen-on-oxidative-stress-markers-and-endurance-performance-in-young-soccer-players-a-pilot-study
#2
Carlos Burgos, Carlos Henríquez-Olguín, David Cristóbal Andrade, Rodrigo Ramírez-Campillo, Oscar F Araneda, Allan White, Hugo Cerda-Kohler
The aim of the present study was to determine the effects of three weeks of hyperbaric oxygen (HBO2) training on oxidative stress markers and endurance performance in young soccer players. Participants (18.6 ± 1.6 years) were randomized into hyperbaric-hyperoxic (HH) training (n = 6) and normobaric normoxic (NN) training (n = 6) groups. Immediately before and after the 5th, 10th, and 15th training sessions, plasma oxidative stress markers (lipid hydroperoxides and uric acid), plasma antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid [TROLOX]), arterial blood gases, acid-base balance, bases excess (BE), and blood lactate analyses were performed...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28053781/potential-benefits-of-jujube-zizyphus-lotus-l-bioactive-compounds-for-nutrition-and-health
#3
REVIEW
Souleymane Abdoul-Azize
Zizyphus lotus, belonging to the Rhamnaceae family, is a deciduous shrub which generally grows in arid and semiarid regions of the globe. In traditional medicine, Z. lotus is used as antidiabetes, sedative, bronchitis, and antidiarrhea by local populations. Recently, several scientific reports for health benefit and nutritional potential of bioactive compounds from this jujube have been reported. This plant is rich in polyphenols, cyclopeptide alkaloids, dammarane saponins, vitamins, minerals, amino acids, and polyunsaturated fatty acids...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28050282/effect-of-the-lipoxygenase-inhibitor-baicalein-on-muscles-in-ovariectomized-rats
#4
D Saul, J H Kling, R L Kosinsky, D B Hoffmann, M Komrakova, M Wicke, B Menger, S Sehmisch
Sarcopenia, a loss of muscle mass accompanying osteoporosis, leads to falls and fall-related injuries. Baicalein, as a phytochemical agent, has an antioxidative and anti-inflammatory effect in muscle. In this study, sixty-one female Sprague Dawley rats were divided into five groups: four groups were ovariectomized (OVX) and one control group was nonovariectomized (NON-OVX). Eight weeks after ovariectomy, three disparate concentrations (1 mg/kg body weight (BW), 10 mg/kg BW, and 100 mg/kg BW) of baicalein were applied subcutaneously daily in three OVX groups...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28050281/ghanaians-might-be-at-risk-of-inadequate-dietary-intake-of-potassium
#5
David Oscar Yawson, Michael Osei Adu, Benjamin Ason, Frederick Ato Armah, Emmanuel Boateng, Reggie Quansah
Adequate dietary intake of potassium (K) helps fight noncommunicable diseases (NCDs), mainly hypertension and cardiovascular diseases. This paper (i) estimated the K intake of Ghanaian population using food supply and food composition data and (ii) compared this estimate with the WHO recommended requirement for K in order to assess if there is a risk of inadequate K intake. Food supply data (1961-2011) was obtained from the FAO Food Balance Sheet (FBS) to derive trends in food and K supply. The average food supply in the FBS for 2010 and 2011 was used in assessing the risk of inadequate dietary intake of K...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28050280/evaluation-of-the-anti-inflammatory-effect-of-locally-delivered-vitamin-c-in-the-treatment-of-persistent-gingival-inflammation-clinical-and-histopathological-study
#6
Nermin M Yussif, Manar A Abdul Aziz, Ahmed R Abdel Rahman
Objective. The purpose of this study is to investigate the role and efficiency of the locally injected vitamin C in the treatment of persistent gingival inflammation. Design. Twenty adult patients with persistent chronic gingival inflammation were included in this study. The same dose of sterile vitamin C was injected in gingival tissues after the completion of phase I therapy. Gingival biopsies were taken after total resolution of inflammation. The specimens were examined histologically, using H&E stain. Results...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27957339/gender-and-racial-differences-in-the-cardiovascular-risk-factors-among-overweight-and-obese-rural-adults-kuching-and-samarahan-division-sarawak-malaysia
#7
Whye Lian Cheah, Ching Thon Chang, Helmy Hazmi, Wan Manan Wan Muda
Objective. This study aimed to determine whether gender and ethnic differences had an effect on cardiovascular risk factors in overweight and obese rural adults in Sarawak. Design and Setting. This was a cross-sectional study conducted in rural communities in Kuching and Samarahan division, Malaysia. Data was obtained using a set of questionnaire (sociodemographic data and physical activity), measurement of blood pressure, height, weight (body mass index, BMI), body fat percentage, fasting blood sugar, and lipid profile from three ethnic groups-Iban, Malay, and Bidayuh...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27872757/sports-nutrition-knowledge-among-mid-major-division-i-university-student-athletes
#8
Ashley Andrews, Janet R Wojcik, Joni M Boyd, Charles J Bowers
Competitive athletes have goals to optimize performance and to maintain healthy body composition. Sports nutrition is a component of training programs often overlooked by student-athletes and their coaches. The purpose of this study was to examine student-athletes' sports nutrition knowledge across sex, class level, team, and completion of prior nutrition coursework. Participants included 123 mid-major Division I university student-athletes (47 females and 76 males) from baseball, softball, men's soccer, track and field, and tennis...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27840740/serum-metabolomic-response-to-long-term-supplementation-with-all-rac-%C3%AE-tocopheryl-acetate-in-a-randomized-controlled-trial
#9
Alison M Mondul, Steven C Moore, Stephanie J Weinstein, Anne M Evans, Edward D Karoly, Satu Männistö, Joshua N Sampson, Demetrius Albanes
Background. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study, a randomized controlled cancer prevention trial, showed a 32% reduction in prostate cancer incidence in response to vitamin E supplementation. Two other trials were not confirmatory, however. Objective. We compared the change in serum metabolome of the ATBC Study participants randomized to receive vitamin E to those who were not by randomly selecting 50 men from each of the intervention groups (50 mg/day all-rac-α-tocopheryl acetate (ATA), 20 mg/day β-carotene, both, placebo)...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27818793/transient-decrease-in-circulatory-testosterone-and-homocysteine-precedes-the-development-of-metabolic-syndrome-features-in-fructose-fed-sprague-dawley-rats
#10
Anil Sakamuri, Sujatha Pitla, Uday Kumar Putcha, Sugeedha Jayapal, Sailaja Pothana, Sai Santosh Vadakattu, Nagabhushan Reddy Konapalli, Siva Sankara Vara Prasad Sakamuri, Ahamed Ibrahim
Background. Increased fructose consumption is linked to the development of metabolic syndrome (MS). Here we investigated the time course of development of MS features in high-fructose-fed Sprague Dawley rats along with circulatory testosterone and homocysteine levels. Methods. Rats were divided into control and experimental groups and fed with diets containing 54.5% starch and fructose, respectively, for 4, 12, and 24 weeks. Plasma testosterone and homocysteine levels were measured along with insulin, glucose, and lipids...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27807480/a-high-protein-diet-has-no-harmful-effects-a-one-year-crossover-study-in-resistance-trained-males
#11
Jose Antonio, Anya Ellerbroek, Tobin Silver, Leonel Vargas, Armando Tamayo, Richard Buehn, Corey A Peacock
The purpose of this investigation was to determine the effects of a high protein diet over a one-year period. Fourteen healthy resistance-trained men completed the study (mean ± SD; age 26.3 ± 3.9 yr; height 178.5 ± 8.4 cm; and average years of training 8.9 ± 3.4 yr). In a randomized crossover design, subjects consumed their habitual or normal diet for 2 months and 4 months and alternated that with a higher protein diet (>3 g/kg/d) for 2 months and 4 months. Thus, on average, each subject was on their normal diet for 6 months and a higher protein diet for 6 months...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27774317/malnutrition-the-importance-of-identification-documentation-and-coding-in-the-acute-care-setting
#12
Jane Kellett, Greg Kyle, Catherine Itsiopoulos, Mark Naunton, Narelle Luff
Malnutrition is a significant issue in the hospital setting. This cross-sectional, observational study determined the prevalence of malnutrition amongst 189 adult inpatients in a teaching hospital using the Patient-Generated Subjective Global Assessment tool and compared data to control groups for coding of malnutrition to determine the estimated unclaimed financial reimbursement associated with this comorbidity. Fifty-three percent of inpatients were classified as malnourished. Significant associations were found between malnutrition and increasing age, decreasing body mass index, and increased length of stay...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27774316/effect-of-treatment-with-salsalate-menhaden-oil-combination-of-salsalate-and-menhaden-oil-or-resolvin-d1-of-c57bl-6j-type-1-diabetic-mouse-on-neuropathic-endpoints
#13
Matthew S Yorek, Lawrence J Coppey, Hanna Shevalye, Alexander Obrosov, Randy H Kardon, Mark A Yorek
Aims. In this study a streptozotocin induced type 1 diabetes mouse model was used to assess the effectiveness of salsalate, menhaden oil, the combination of salsalate and menhaden oil, or resolvin D1 on neuropathic endpoints. Materials and Methods. Changes in body weight, blood glucose, serum markers for triglycerides, free fatty acids, cholesterol, and resolvin D1, motor and sensory nerve conduction velocities and thermal sensitivity were assessed, as well as performing in vivo confocal microscopy of subepithelial corneal nerves and immunohistochemistry of nerves in the cornea and foot pad...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27738523/exercising-in-the-fasted-state-reduced-24-hour-energy-intake-in-active-male-adults
#14
Jessica L Bachman, Ronald W Deitrick, Angela R Hillman
The effect of fasting prior to morning exercise on 24-hour energy intake was examined using a randomized, counterbalanced design. Participants (12 active, white males, 20.8 ± 3.0 years old, VO2max: 59.1 ± 5.7 mL/kg/min) fasted (NoBK) or received breakfast (BK) and then ran for 60 minutes at 60%  VO2max. All food was weighed and measured for 24 hours. Measures of blood glucose and hunger were collected at 5 time points. Respiratory quotient (RQ) was measured during exercise. Generalized linear mixed models and paired sample t-tests examined differences between the conditions...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27703806/schoolchildren-with-learning-difficulties-have-low-iron-status-and-high-anemia-prevalence
#15
F P N Arcanjo, C P C Arcanjo, P R Santos
Background. In developing countries there is high prevalence of iron deficiency anemia, which reduces cognitive performance, work performance, and endurance; it also causes learning difficulties and negative impact on development for infant population. Methods. The study concerns a case-control study; data was collected from an appropriate sample consisting of schoolchildren aged 8 years. The sample was divided into two subgroups: those with deficient initial reading skills (DIRS) (case) and those without (control)...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27630772/novel-form-of-curcumin-improves-endothelial-function-in-young-healthy-individuals-a-double-blind-placebo-controlled-study
#16
Jonathan M Oliver, Lee Stoner, David S Rowlands, Aaron R Caldwell, Elizabeth Sanders, Andreas Kreutzer, Joel B Mitchell, Martin Purpura, Ralf Jäger
Curcumin, a turmeric extract, may protect against cardiovascular diseases by enhancing endothelial function. In this randomized controlled double-blind parallel prospective study, fifty-nine healthy adults were assigned to placebo, 50 mg (50 mg), or 200 mg (200 mg) curcumin, for 8 weeks. The higher curcumin (200 mg) supplementation produced a dose-mediated improvement in endothelial function measured by flow-mediated dilation (FMD). The outcome was a clinically substantial 3.0% increase (90% CI 0...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27595018/nutrition-from-bench-to-bedside
#17
EDITORIAL
Naim A Khan, Azeddine Ibrahimi, Aziz Hichami, Najat Mokhtar
No abstract text is available yet for this article.
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27429803/effects-of-a-multispecies-probiotic-mixture-on-glycemic-control-and-inflammatory-status-in-women-with-gestational-diabetes-a-randomized-controlled-clinical-trial
#18
Sadegh Jafarnejad, Sadaf Saremi, Farzan Jafarnejad, Arman Arab
Objective. This trial aims to examine the effects of a Probiotic Mixture (VSL#3) on glycemic status and inflammatory markers, in women with GDM. Materials and Methods. Over a period of 8 weeks, 82 women with gestational diabetes were randomly assigned to either an intervention group (n = 41) which were given VSL#3 capsule or to a control group which were given placebo capsule (n = 41). Fasting plasma glucose, homeostatic model assessment of insulin resistance, glycosylated hemoglobin, high-sensitivity C-reactive protein, tumor necrosis factor-α, interleukin-6, Interferon gamma, and interleukin-10 were measured before and after the intervention...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27429802/effects-of-dietary-strawberry-supplementation-on-antioxidant-biomarkers-in-obese-adults-with-above-optimal-serum-lipids
#19
Arpita Basu, Stacy Morris, Angel Nguyen, Nancy M Betts, Dongxu Fu, Timothy J Lyons
Berries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [n = 60; age: 49 ± 10 years; BMI: 36 ± 5 kg/m(2) (mean ± SD)] with abdominal adiposity and elevated serum lipids. Participants were randomized to one of the following arms: low dose strawberry (25 g/day FDS), low dose control beverage (LD-C), high dose strawberry (50 g/d FDS), and high dose control beverage (HD-C) for 12 weeks...
2016: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/27413547/increased-gustatory-response-score-in-obesity-and-association-levels-with-il-6-and-leptin
#20
Nesrine Remla, Zeyneb Hadjidj, Kamel Ghezzaz, Soraya Moulessehoul, Mourad Aribi
Background. The aim of this study was to investigate the relationship between the circulating IL-6 and leptin levels with taste alteration in young obese patients. Methods. A retrospective case-control study was conducted in thirty obese patients and thirty age- and sex-matched healthy controls. Results. Circulating levels of IL-6 and leptin were significantly increased in obese patients than in controls. However, catalase and ORAC levels were significantly decreased in obese patients compared to controls. Additionally, obese participants had high scores for the detection of fats (gustatory response scores [GRS]; p < 0...
2016: Journal of Nutrition and Metabolism
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