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Journal of Nutrition and Metabolism

Shiferaw Abeway, Bereket Gebremichael, Rajalakshmi Murugan, Masresha Assefa, Yohannes Mehretie Adinew
Background: Stunting reflects chronic undernutrition during the most critical periods of growth and development in early life. The study was aimed at assessing the magnitude of stunting and associated factors among children aged 6-59 month in central Ethiopia. Methods: A community-based cross-sectional study was conducted among 410 children aged between 6 and 59 months. Systematic random sampling technique was employed to select study participants. Interviewer-administered structured questionnaire was used to collect data...
2018: Journal of Nutrition and Metabolism
Tona Zema Diddana, Gezahegn Nigusse Kelkay, Amanuel Nana Dola, Abinet Arega Sadore
Background: In Ethiopia, poor dietary practice among pregnant women ranges from 39.3 to 66.1%. Limited nutritional knowledge and wrong perception towards dietary behaviours were underlying factors. Hence, this study was aimed to determine the effect of nutrition education based on Health Belief Model on nutritional knowledge and dietary practice of pregnant women in Dissie town, northeast Ethiopia, 2017 GC. Methods: Community-based cluster randomized control trial was employed...
2018: Journal of Nutrition and Metabolism
Anne Clark, Deirdre Deverell, Emma Corcoran, Margaret Macauley, Nicola Newcombe, Peter Branagan, Aoife Coughlan, Eimear Daly, Aoibhin Moore Heslin, Ellen Crushell, Joanne Hughes, Ina Knerr, Ahmad Monavari
The Metabolic Dietetic Team in the National Centre for Inherited Metabolic Disorders (NCIMD) in Ireland deals with approximately 120 weekly phenylalanine (Phe) levels for both adults and children. A review of 500 Phe levels highlighted that 52% of the results were within the target range. Collaboration between information and communication technologies (ICT) departments, metabolic laboratory, and metabolic dietitians enabled the development of the PKU texting system. Following a successful pilot study, the system was then offered to all PKU patients aged over 2 years...
2018: Journal of Nutrition and Metabolism
Tom L Broderick, Frank A Cusimano, Chelsea Carlson, Jeganathan Ramesh Babu
We determined whether one single bout of exercise stimulates carnitine biosynthesis and carnitine uptake in liver and heart. Free carnitine (FC) in plasma was assayed using acetyltransferase and [14 C]acetyl-CoA in Swiss Webster mice after 1 hour of moderate-intensity treadmill running or 4 hours and 8 hours into recovery. Liver and heart were removed under the same conditions for measurement of carnitine biosynthesis enzymes (liver butyrobetaine hydroxylase, γ-BBH; heart trimethyllysine dioxygenase, TMLD), organic cation transporter-2 (OCTN2, carnitine transporter), and liver peroxisome proliferator-activated receptor-alpha (PPAR α , transcription factor for γ -BBH and OCTN2 synthesis)...
2018: Journal of Nutrition and Metabolism
David Larbi Simpong, Yaw Asante Awuku, Kenneth Kwame Kye-Amoah, Martin Tangnaa Morna, Prince Adoba, Stephen Kofi Anin, Patrick Adu
Background: Iodine deficiency causes maternal hypothyroidism which can lead to growth, cognitive, and psychomotor deficit in neonates, infants, and children. This study examined the iodine status of pregnant women in a periurban setting in Ghana. Methods: This longitudinal study recruited 125 pregnant women by purposeful convenience sampling from the antenatal clinic of the Sefwi Wiawso municipal hospital in Ghana. Urinary iodine concentration (UIC) was estimated by the ammonium persulfate method at an estimated gestational age (EGA) of 11, 20, and 32 weeks...
2018: Journal of Nutrition and Metabolism
Cliff J D C Harvey, Grant M Schofield, Micalla Williden, Joseph A McQuillan
Medium chain triglycerides (MCTs) are ketogenic and might reduce adverse effects of keto-induction and improve time to ketosis and the tolerability of very low carbohydrate diets. This study investigates whether MCT supplementation improves time to nutritional ketosis (NK), mood, and symptoms of keto-induction. We compared changes in beta-hydroxybutyrate (BOHB), blood glucose, symptoms of keto-induction, and mood disturbance, in 28 healthy adults prescribed a ketogenic diet, randomised to receive either 30 ml of MCT, or sunflower oil as a control, three times per day, for 20 days...
2018: Journal of Nutrition and Metabolism
Jay T Sutliffe, Mary Jo Carnot, Joel H Fuhrman, Chloe A Sutliffe, Julia C Scheid
Background: Worksite dietary interventions show substantial potential for improving employee health and well-being. The aim of this pilot study was to determine the effect of a worksite nutrition intervention on improving well-being. Methods: Thirty-five university employees participated in a 6-week nutrition intervention. The dietary protocol emphasized the daily consumption of greens, beans/legumes, a variety of other vegetables, fruits, nuts, seeds, and whole grains, referred to as a micronutrient-dense, plant-rich diet...
2018: Journal of Nutrition and Metabolism
John Georges, Matthew H Sharp, Ryan P Lowery, Jacob M Wilson, Martin Purpura, Troy A Hornberger, Flint Harding, James H Johnson, David M Peele, Ralf Jäger
Introduction: Krill oil supplementation has been shown to improve postexercise immune function; however, its effect on muscle hypertrophy is currently unknown. Therefore, the aim of present study was to investigate the ability of krill oil to stimulate mTOR signaling and its ability to augment resistance training-induced changes in body composition and performance. Methods: C2 C12 myoblasts cells were stimulated with krill oil or soy-derived phosphatidylcholine (S-PC), and then, the ratio of P-p70-389 to total p70 was used as readout for mTOR signaling...
2018: Journal of Nutrition and Metabolism
César Estrada-Reyes, Patricia Tlatempa-Sotelo, Roxana Valdés-Ramos, María Cabañas-Armesilla, Rafael Manjarrez-Montes-de-Oca
Background: Nowadays, the term "physical fitness" has evolved from sports performance to health status, and it has been considered a strong predictor of cardiovascular disease. In this sense, test batteries have been developed to evaluate physical fitness such as the ALPHA-FIT battery. On the other hand, the analysis of dietary patterns has emerged as an alternative method to study the relationship between diet and chronic noncommunicable diseases. However, the association between dietary patterns and the physical fitness level has not been evaluated in both adults and adolescents...
2018: Journal of Nutrition and Metabolism
Ivi R Back, Rosana R Oliveira, Eraldo S Silva, Sonia S Marcon
Objective: To estimate which risk factors (sociodemographic, lifestyle, and health conditions) are associated with overweight and obesity in Japanese-Brazilians. Methods: This was a cross-sectional study carried out with Japanese-Brazilians living in the southern region of Brazil. Data were collected between March and December of 2016 through a household survey addressing sociodemographic characteristics, lifestyle, and health conditions. Data were analyzed by means of logistic regression considering 95% level of significance...
2018: Journal of Nutrition and Metabolism
Jaraspong Uaariyapanichkul, Sirinuch Chomtho, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Santi Punnahitananda, Pannee Chinjarernpan, Orapa Suteerojntrakool
Background: Age, race, and analytic method influence levels of blood amino acids, of which reference intervals are required for the diagnosis and management of inherited metabolic disorders. Objectives: To establish age-specific reference intervals for blood amino acids in Thai pediatric population measured by liquid chromatography tandem mass spectrometry (LC-MS/MS). Methods: A cross-sectional study of 277 healthy children from birth to 12 years was conducted...
2018: Journal of Nutrition and Metabolism
Tobias Fischer, Ulrike Och, Ira Klawon, Tim Och, Marianne Grüneberg, Manfred Fobker, Ursula Bordewick-Dell, Thorsten Marquardt
Background: Ketone body therapy and supplementation are of high interest for several medical and nutritional fields. The intake of ketone bodies is often discussed in relation to rare metabolic diseases, such as multiple acyl-CoA dehydrogenase deficiency (MADD), that have no alternatives for treatment. Case reports showed positive results of therapy using ketone bodies. The number of ketone body salts offered on the wellness market is increasing steadily. More information on the kinetics of intake, safety, and tolerance of these products is needed...
2018: Journal of Nutrition and Metabolism
Amina Bouziani, Naima Saeid, Hasnae Benkirane, Latifa Qandoussi, Youness Taboz, Asmaa El Hamdouchi, Khalid El Kari, Mohammed El Mzibri, Hassan Aguenaou
Calcium is an important mineral playing a vital role to maintain bone health. Calcium intake is considered as one of the most important determinants to assess the calcium status and to evaluate the calcium deficiency in the human body. Our study aims at estimating calcium intake in a sample of children and adolescent to be used in the global strategy to reduce calcium deficiency disorders in Morocco. Thus, 131 children and adolescents were recruited from public schools at Rabat and its regions in the framework of a descriptive cross-sectional study...
2018: Journal of Nutrition and Metabolism
Prasanna Mithra, Bhaskaran Unnikrishnan, Rekha Thapar, Nithin Kumar, Sharana Hegde, Anjali Mangaldas Kamat, Vaman Kulkarni, Ramesh Holla, B B Darshan, Kanchan Tanuj, Vasudev Guddattu, Avinash Kumar
Background: Consumption of snacks in between the regular meals is a poor snacking behaviour. It is an established risk factor for several lifestyle-related disorders and has long-term effects among the younger individuals. Objectives: To study the snacking behaviour and to assess their determinants among college-going students. Methods: This cross-sectional study was conducted among 865 college-going students in Mangaluru. Data were collected using a pretested pro forma that was coded and analyzed using Statistical Package for Social Sciences (SPSS) version 11...
2018: Journal of Nutrition and Metabolism
Franco Cavaleri, Emran Bashar
The low-carbohydrate high-fat diet (LCHFD), also known as the ketogenic diet, has cycled in and out of popularity for decades as a therapeutic program to treat metabolic syndrome, weight mismanagement, and drug-resistant disorders as complex as epilepsy, cancer, dementia, and depression. Despite the benefits of this diet, health care professionals still question its safety due to the elevated serum ketones it induces and the limited dietary fiber. To compound the controversy, patient compliance with the program is poor due to the restrictive nature of the diet and symptoms related to energy deficit and gastrointestinal adversity during the introductory and energy substrate transition phase of the diet...
2018: Journal of Nutrition and Metabolism
Carlos Alfredo Galindo Martín, Reyna Del Carmen Ubeda Zelaya, Enrique Monares Zepeda, Octavio Augusto Lescas Méndez
Malnutrition (undernutrition) encompasses low intake or uptake, loss of fat mass, and muscle wasting and is associated with worse outcomes. Ultrasound has been introduced in the intensive care unit as a tool to assess muscle mass. The aim of the present study is to explore the relation between initial muscle mass and mortality in adult patients admitted to the intensive care unit. Methods . Rectus femoris and vastus intermedius thicknesses were measured by B-mode ultrasound in adult patients at admission, along with demographic characteristics, illness severity, comorbidities, biochemical variables, treatments, and in-hospital mortality as main outcomes...
2018: Journal of Nutrition and Metabolism
David E Andrich, Lilya Melbouci, Ya Ou, Jean-Philippe Leduc-Gaudet, François Chabot, François Lalonde, Fábio Santos Lira, Bruce D Gaylinn, Gilles Gouspillou, Gawiyou Danialou, Alain-Steve Comtois, David H St-Pierre
Information regarding the early effects of obesogenic diets on feeding patterns and behaviors is limited. To improve knowledge regarding the etiology of obesity, young male Wistar rats were submitted to high-fat (HFD) or regular chow diets (RCDs) for 14 days. Various metabolic parameters were continuously measured using metabolic chambers. Total weight gain was similar between groups, but heavier visceral fat depots and reduced weight of livers were found in HFD rats. Total calorie intake was increased while individual feeding bouts were shorter and of higher calorie intake in response to HFD...
2018: Journal of Nutrition and Metabolism
Dereje Yohannes Teferi, Gudina Egata Atomssa, Tefera Chane Mekonnen
Background: This study aimed to assess the prevalence of malnutrition and associated factors among school adolescents in Wolaita Sodo town, Southern Ethiopia. Methods: A school-based cross-sectional study was conducted from May 18-June 10, 2015. A multistage sampling was used to select a random sample of 690 adolescents from selected schools. Data on sociodemographic information were collected by using an interviewer-administered questionnaire, and anthropometric measurements were made by using a digital Seca scale and height measuring board by trained data collectors...
2018: Journal of Nutrition and Metabolism
Samuel Smith, Isaac Okai, Chrissie Stansie Abaidoo, Emmanuel Acheampong
ABO blood group and body mass index (BMI) have individually been appraised as risk factors for certain diseases. From statistical perspective, it may be important to examine the relationship between the ABO blood antigen and BMI. This cross-sectional study involved 412 participants aged 18 to 46 at the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. Weight and height of participants were measured for BMI calculation; blood group determination was done using antisera. Blood group O was the most prevalent (51...
2018: Journal of Nutrition and Metabolism
María Ximena Silveyra, María Luciana Lanteri, Rocío Belén Damiano, Adriana Balbina Andreu
Potatoes ( Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal, and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp. tuberosum (Summerside), and three S. tuberosum spp. andigena (landraces Moradita, Waicha, and Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh...
2018: Journal of Nutrition and Metabolism
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