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Journal of Parasitology Research

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https://www.readbyqxmd.com/read/30225138/inhibitory-activity-and-docking-analysis-of-antimalarial-agents-from-stemona-sp-toward-ferredoxin-nadp-reductase-from-malaria-parasites
#1
Pratiwi Pudjiastuti, Ni Nyoman T Puspaningsih, Imam Siswanto, Much Z Fanani, Yoko K Ariga, Toshiharu Hase, Satyajit D Sarker, Lutfun Nahar
Ferredoxin-NADP+ reductases (FNRs, EC 1.18.1.2) were found in the plastids of Plasmodium and have been considered as a target for the development of new antimalarial agents. Croomine, epi -croomine, tuberostemonine, javastemonine A, and isoprotostemonine are isolated alkaloids from the roots of Stemona sp. and their inhibitory effect on FNRs from Plasmodium falciparum (Pf FNR) was investigated. Croomine showed the highest level of inhibition (33.9%) of electron transfer from Pf FNR to Pf Fd, while tuberstemonine displayed the highest level of inhibition (55...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30147947/prevalence-of-intestinal-parasitic-infections-among-patients-of-king-fahd-medical-city-in-riyadh-region-saudi-arabia-a-5-year-retrospective-study
#2
Omar S O Amer, Esam S Al-Malki, Mohamed I Waly, Abdulaziz AlAgeel, Mahmoud Y Lubbad
This study is a retrospective analysis of the recorded intestinal parasitic infections for in- and outpatients visiting King Fahd Medical City, Riyadh, Saudi Arabia, from 2013 to 2017. In this study, a total of 5987 in- and outpatient were examined for intestinal parasitic infection. 30 patients out of 5987 were infected with 6 species of intestinal parasites with prevalence rate 0.5%. These parasites were Entamoeba histolytica (P = 0.27%), Cryptosporidium sp. (P = 0.1%), Giardia lamblia (P = 0.07%), Trichuris trichiura (P = 0...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30112194/-clups-a-new-culture-medium-for-the-axenic-growth-of-entamoeba-histolytica
#3
F Gonzalez-Salazar, I Meester, F J Guzmán De La Garza, L H De La Garza-Salinas, A Sampayo-Reyes, J N Garza-Gonzalez, O Monsivais-Diaz, B A Barba-Dávila, M E Hernández-García, J Vargas-Villarreal
Amebiasis remains a major health problem in Mexico. Therefore, the search for better culture media and low-cost diagnostic and therapeutic tools is fundamental. We present a new culture medium for Entamoeba histolytica which allows the microbe to preserve its virulence factors and ability to induce hepatic abscesses in animal models. The novel CLUPS medium is an improved version of the PEHPS medium, previously designed in our laboratory. The main difference is the substitution of raw beef liver in PEHPS by raw beef lung in the CLUPS medium...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30057801/the-search-for-an-efficient-black-fly-trap-for-xenomonitoring-of-onchocerciasis
#4
REVIEW
Kenneth B Otabil, Samuel F Gyasi, Esi Awuah, Daniels Obeng-Ofori, Mario A Rodríguez-Pérez, Charles R Katholi, Thomas R Unnasch
Onchocerciasis is a neglected tropical disease that has plagued mankind for decades with pathologies that involve the eyes and the skin. The WHO and the global health community have earmarked the disease for global elimination by 2045. However, as control programmes shift focus from reduction of the burden of the disease to elimination, new tools and strategies may be needed to meet targets. Monitoring Onchocerca volvulus larvae in the black fly vectors is an important tool needed to monitor disease dynamics and certify elimination...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30050688/larvicidal-effectiveness-of-azolla-pinnata-against-aedes-aegypti-diptera-culicidae-with-its-effects-on-larval-morphology-and-visualization-of-behavioural-response
#5
Nor Shaida Husna Zulkrnin, Nurul Nadiah Rozhan, Nur Amanina Zulkfili, Nik Raihan Nik Yusoff, Mohd Sukhairi Mat Rasat, Nor Hakimin Abdullah, Muhammad Iqbal Ahmad, Rajiv Ravi, Intan H Ishak, Mohamad Faiz Mohd Amin
Dengue is vector-borne diseases with 390 million infections per year extending over 120 countries of the world. Aedes aegypti (L.) (Diptera: Culicidae) is a primary vector for dengue viral infections for humans. Current focus on application of natural product against mosquito vectors has been the main priority for research due to its eco-safety. The extensive use of chemical insecticides has led to severe health problems, environmental pollution, toxic hazards to human and nontarget species, and development of insecticide resistance on mosquitoes...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30013798/development-and-evaluation-of-a-loop-mediated-isothermal-amplification-assay-for-diagnosis-of-schistosoma-mansoni-infection-in-faecal-samples
#6
Ibrahim N Mwangi, Eric L Agola, Robert M Mugambi, Esther A Shiraho, Gerald M Mkoji
Human intestinal schistosomiasis is caused by the blood fluke, Schistosoma mansoni. With intensified efforts to control schistosomiasis by mass drug administration using praziquantel (PZQ), there is an urgent need to have accessible, quality-assured diagnostic tests for case detection and disease surveillance and for monitoring efficacy of treatment and other interventions. Current diagnostic tools are limited by suboptimal sensitivity, slow turn-around-time, affordability, and inability to distinguish current from past infections...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30009046/synergetic-effects-of-plasmodium-hookworm-and-schistosoma-mansoni-infections-on-hemoglobin-level-among-febrile-school-age-children-in-jawe-worda-northwest-ethiopia
#7
Tadesse Hailu, Mulat Yimer, Wondemagegn Mulu, Bayeh Abera
Plasmodium coinfection with hookworm and/or Schistosoma mansoni has detrimental effects on human's hemoglobin level. This study aimed to determine the effects of plasmodium, hookworm, and S. mansoni infections on hemoglobin level among febrile school age children in Northwest Ethiopia. A cross-sectional study was conducted from April 2016 to August 2016. Plasmodium and helminths infections were detected using Giemsa stain and formol-ether concentration techniques, respectively. Hemoglobin level was determined using Hemocue method...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29977614/effect-of-phenotypic-screening-of-extracts-and-fractions-of-erythrophleum-ivorense-leaf-and-stem-bark-on-immature-and-adult-stages-of-schistosoma-mansoni
#8
Gertrude Kyere-Davies, Christian Agyare, Yaw Duah Boakye, Brian M Suzuki, Conor R Caffrey
Schistosomiasis is a disease caused by a flatworm parasite that infects people in tropical and subtropical regions of Sub-Saharan Africa, South America, China, and Southeast Asia. The reliance on just one drug for current treatment emphasizes the need for new chemotherapeutic strategies. The aim of this study was to determine the phenotypic effects of extracts and fractions of leaf and stem bark of Erythrophleum ivorense (family Euphorbiaceae), a tree that grows in tropical parts of Africa, on two developmental stages of Schistosoma mansoni , namely, postinfective larvae (schistosomula or somules) and adults...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29862062/knowledge-attitude-and-beliefs-of-communities-and-health-staff-about-echinococcus-granulosus-infection-in-selected-pastoral-and-agropastoral-regions-of-uganda
#9
Emmanuel Othieno, Michael Ocaido, Ezekiel Mupere, Leonard Omadang, Peter Oba, Andrew Livex Okwi
A descriptive cross-sectional survey was done to determine knowledge, attitudes, and beliefs of the communities and health workers about cystic echinococcosis (CE) in pastoral region of Northeastern (NE) and agropastoral regions of Eastern (E) and Central (C) Uganda. Overall a total of 1310 participants were interviewed. Community respondents from NE region were more aware of CE infection than those from Eastern (OR 4.85; CI: 3.60-6.60; p < 0.001) and Central (OR 5.73; CI: 4.22-7.82; p < 0.001) regions...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29854422/prevalence-of-toxoplasma-gondii-neospora-caninum-and-sarcocystis-species-dna-in-the-heart-and-breast-muscles-of-rock-pigeons-columbia-livia
#10
Muhammad Mudasser Nazir, Muhammad Mazhar Ayaz, Atif Nisar Ahmed, Azhar Maqbool, Kamran Ashraf, Muhammad Oneeb, Ghulam Yasin, Atta Subhani, Muhammad Asif Ali, Noman Nazir, Muhammad Afzal Sajid
Little is known about the prevalence of protozoan parasites in the muscles of rock pigeons (Columbia livia) . The muscles from 54 (heart from 45 and breast from 54) rock pigeons were examined for DNA of Toxoplasma gondii , Neospora caninum, and Sarcocystis species using PCR. Twenty-four were female and 30 were males. The birds were part of flocks of pigeons housed at the tombs of saints in Lahore, Pakistan. Birds that died or were euthanized due to poor health were submitted for necropsy at the Department of Parasitology, University of Veterinary and Animal Sciences, Lahore, Pakistan, where DNA isolations and PCR were conducted...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29770229/sensitivity-of-different-cattle-breeds-to-the-infestation-of-cattle-ticks-amblyomma-variegatum-rhipicephalus-microplus-and-hyalomma-spp-on-the-natural-pastures-of-opkara-farm-benin
#11
Roland Eric Yessinou, Camus Adoligbe, Yao Akpo, Justin Adinci, Issaka Youssao Abdou Karim, Souaïbou Farougou
A study was carried out on the Opkara (Benin) cattle farm on 64 cattle of four different breeds (16 individuals per breed) from June to December 2016. During this study, three tick species were found in different numbers, Amblyomma variegatum (732), Rhipicephalus microplus (8079), and Hyalomma spp. (208), with parasitic intensity of 11.90, 126.23, and 3.25, respectively. The interracial comparison of the tick infestation between the cattle showed a significant difference ( P < 0.001). However, Girolando was more infested than all the cattle breeds...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29692928/a-novel-application-of-an-anthelmintic-mixture-for-use-against-gastrointestinal-parasites-of-red-deer-cervus-elaphus
#12
P L Hughes
A mixture of proprietary anthelmintics delivering 0.5 mg/kg moxidectin, 9.06 mg/kg oxfendazole, 15 mg/kg levamisole, and 0.08 mg/kg selenium on bodyweight basis per os to red deer is investigated. On a deer farm with a history of parasite problems, six weaner red deer were treated orally with a 50/50 mixture of Exodus Pour-On and Oxfen C Plus (Ex/Ox) at a dose rate of 1 ml/5 kg bodyweight. Six herd mates were untreated. Eleven days later abomasal worm counts for the untreated deer revealed an arithmetic mean burden of 2,566 Ostertagia -type worms and 300 Trichostrongylus axei ...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29666698/prevalence-of-intestinal-parasites-and-associated-factors-among-pulmonary-tuberculosis-suspected-patients-attending-university-of-gondar-hospital-gondar-northwest-ethiopia
#13
Yalewayker Tegegne, Tadelo Wondmagegn, Ligabaw Worku, Ayalew Jejaw Zeleke
Introduction: Intestinal parasitic infections are among the major public health problems in developing countries. Hence, it is significant to explore coinfection with intestinal parasites and pulmonary tuberculosis because coinfection increases the complexity of control and prevention of pulmonary tuberculosis and parasitic diseases. Objective: To assess the prevalence of intestinal parasites among pulmonary tuberculosis suspected patients. Method: Institutional based cross-sectional study was conducted at University of Gondar Hospital from March to May, 2017...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29610679/low-il-6-il-10-and-tnf-%C3%AE-and-high-il-13-cytokine-levels-are-associated-with-severe-hepatic-fibrosis-in-schistosoma-mansoni-chronically-exposed-individuals
#14
Mable M Mutengo, Takafira Mduluza, Paul Kelly, James C L Mwansa, Geoffrey Kwenda, Patrick Musonda, James Chipeta
Several studies have attributed the etiopathogenesis of chronic Schistosoma mansoni related hepatic fibrosis to unregulated immune responses against trapped parasite ova in the host. However, there is limited data on immune profiles associated with varying degrees of the disease in a population under chronic exposure to the parasite. We therefore investigated the role of selected T-helper (Th)1, Th2, and Th17 cytokines in relation to hepatic fibrosis severity among individuals resident in a hyper- Schistosoma mansoni endemic region of Western Zambia...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29593896/enteroparasites-in-riverside-settlements-in-the-pantanal-wetlands-ecosystem
#15
Patrícia Vieira da Silva, Lucimare Dos Santos Maciel, Ludiele Souza Castro, Paula Guerra Murat, Minoru German Higa Junior, Patrícia Honorato Zerlotti, Ana Rita Coimbra Motta-Castro, Elenir Rose Jardim Cury Pontes, Maria Elizabeth Cavalheiros Dorval
Background: Intestinal parasites are a major source of health problems in developing countries, where socioeconomic, cultural, and environmental conditions contribute in maintaining the biological cycles of various parasites and facilitating their spread. The objective of this study, conducted in Corumbá, Mato Grosso do Sul state, Brazil, was to investigate the occurrence of intestinal parasites in riverside communities in the South Pantanal wetlands and conduct educational interventions focused on health and environmental preservation...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29593895/cross-sectional-serological-survey-of-human-fascioliasis-in-canutama-municipality-in-western-amazon-brazil
#16
Marcel Gonçalves Maciel, Walter Dos Santos Lima, Francisco Lazaro Moreira de Almeida, Leila Inês Aguiar Raposo Câmara Coelho, Guilherme Alfredo Novelino Araújo, Mariana Gomes Lima, Luiz Henrique Gonçalves Maciel, Cíntia Aparecida de Jesus Pereira, Thaís Costa da Silva Maciel, Jorge Augusto de Oliveira Guerra, Rosa Amélia Gonçalves Santana, Maria das Graças Vale Barbosa Guerra
Background: Fascioliasis is an important parasitic disease. In the northern region of Brazil, a human parasite infection has been reported through a coprological survey. Eggs of Fasciola hepatica were found in fecal samples of 11 individuals. Knowledge of the infection in animals or the presence of snails is necessary to address the possibility of the parasite cycle occurrence in that region. The aim of this study was to describe the transmission of human fascioliasis in Canutama, Amazonas, in Western Amazonia, Brazil...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29568648/barriers-to-diagnosis-access-for-chagas-disease-in-colombia
#17
Mario Javier Olivera, Julián Felipe Porras Villamil, Christian Camilo Toquica Gahona, Jorge Martín Rodríguez Hernández
Chagas disease is the leading cause of nonischemic cardiomyopathy in Latin America. Timely access to diagnosis and trypanocidal treatment and preventive tools for millions of infected people continues to be a challenge. The purpose of this study was to identify potential barriers for the diagnosis of Chagas disease in Colombia from the perspective of healthcare providers. Using a simultaneous mixed-methods study design, we analyzed trends in access to screening and diagnosis for Chagas disease in Colombia and assessed the national barriers to access...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29410911/performance-of-laboratory-professionals-working-on-malaria-microscopy-in-tigray-north-ethiopia
#18
Megbaru Alemu, Desalegn Tadesse, Tesfaye Hailu, Wondemagegn Mulu, Awoke Derbie, Tadesse Hailu, Bayeh Abera
Background: Microscopic analysis of stained blood smear is the most suitable method of malaria diagnosis. However, gaps were observed among clinical laboratory professionals in microscopic diagnosis of malaria. Methods: A cross-sectional study was conducted in December 2015 among 46 laboratory professionals. Data was collected via on-site assessment and panel testing. The slide panel testing was composed of positive and negative slides. The kappa score was used to estimate the agreement between participants and reference reader...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29391947/-in-vivo-antimalarial-activity-of-the-solvent-fractions-of-fruit-rind-and-root-of-carica-papaya-linn-caricaceae-against-plasmodium-berghei-in-mice
#19
Gemechu Zeleke, Dereje Kebebe, Eshetu Mulisa, Fanta Gashe
Background: Currently, antimalarial drug resistance poses a serious challenge. This stresses the need for newer antimalarial compounds. Carica papaya is used traditionally and showed in vitro antimalarial activity. This study attempted to evaluate in vivo antimalarial activity of C. papaya in mice. Methods: In vivo antimalarial activity of solvent fractions of the plant was carried out against early P. berghei infection in mice. Parasitemia, temperature, PCV, and body weight of mice were recorded...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29379651/intra-abdominal-hydatid-cyst-sociodemographics-clinical-profiles-and-outcomes-of-patients-operated-on-at-a-tertiary-hospital-in-addis-ababa-ethiopia
#20
Engida Abebe, Temesgen Kassa, Mahteme Bekele, Ayelign Tsehay
Background: Hydatid cyst is caused by the tapeworm Echinococcus granulosus . The abdomen, specifically the liver, is the most common site affected. Objective: Determine the presentation patterns, types of surgical management, and outcomes of patients operated for intra-abdominal hydatid cyst (IAHC). Methodology: A retrospective descriptive study of patients admitted and operated for IAHC from September 1, 2011, to August 31, 2015. Results: Forty-two patients whose age ranged from 10 to 65 (mean of 37 years) were operated on...
2017: Journal of Parasitology Research
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