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Journal of Parasitology Research

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https://www.readbyqxmd.com/read/30013798/development-and-evaluation-of-a-loop-mediated-isothermal-amplification-assay-for-diagnosis-of-schistosoma-mansoni-infection-in-faecal-samples
#1
Ibrahim N Mwangi, Eric L Agola, Robert M Mugambi, Esther A Shiraho, Gerald M Mkoji
Human intestinal schistosomiasis is caused by the blood fluke, Schistosoma mansoni. With intensified efforts to control schistosomiasis by mass drug administration using praziquantel (PZQ), there is an urgent need to have accessible, quality-assured diagnostic tests for case detection and disease surveillance and for monitoring efficacy of treatment and other interventions. Current diagnostic tools are limited by suboptimal sensitivity, slow turn-around-time, affordability, and inability to distinguish current from past infections...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/30009046/synergetic-effects-of-plasmodium-hookworm-and-schistosoma-mansoni-infections-on-hemoglobin-level-among-febrile-school-age-children-in-jawe-worda-northwest-ethiopia
#2
Tadesse Hailu, Mulat Yimer, Wondemagegn Mulu, Bayeh Abera
Plasmodium coinfection with hookworm and/or Schistosoma mansoni has detrimental effects on human's hemoglobin level. This study aimed to determine the effects of plasmodium, hookworm, and S. mansoni infections on hemoglobin level among febrile school age children in Northwest Ethiopia. A cross-sectional study was conducted from April 2016 to August 2016. Plasmodium and helminths infections were detected using Giemsa stain and formol-ether concentration techniques, respectively. Hemoglobin level was determined using Hemocue method...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29977614/effect-of-phenotypic-screening-of-extracts-and-fractions-of-erythrophleum-ivorense-leaf-and-stem-bark-on-immature-and-adult-stages-of-schistosoma-mansoni
#3
Gertrude Kyere-Davies, Christian Agyare, Yaw Duah Boakye, Brian M Suzuki, Conor R Caffrey
Schistosomiasis is a disease caused by a flatworm parasite that infects people in tropical and subtropical regions of Sub-Saharan Africa, South America, China, and Southeast Asia. The reliance on just one drug for current treatment emphasizes the need for new chemotherapeutic strategies. The aim of this study was to determine the phenotypic effects of extracts and fractions of leaf and stem bark of Erythrophleum ivorense (family Euphorbiaceae), a tree that grows in tropical parts of Africa, on two developmental stages of Schistosoma mansoni , namely, postinfective larvae (schistosomula or somules) and adults...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29862062/knowledge-attitude-and-beliefs-of-communities-and-health-staff-about-echinococcus-granulosus-infection-in-selected-pastoral-and-agropastoral-regions-of-uganda
#4
Emmanuel Othieno, Michael Ocaido, Ezekiel Mupere, Leonard Omadang, Peter Oba, Andrew Livex Okwi
A descriptive cross-sectional survey was done to determine knowledge, attitudes, and beliefs of the communities and health workers about cystic echinococcosis (CE) in pastoral region of Northeastern (NE) and agropastoral regions of Eastern (E) and Central (C) Uganda. Overall a total of 1310 participants were interviewed. Community respondents from NE region were more aware of CE infection than those from Eastern (OR 4.85; CI: 3.60-6.60; p < 0.001) and Central (OR 5.73; CI: 4.22-7.82; p < 0.001) regions...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29854422/prevalence-of-toxoplasma-gondii-neospora-caninum-and-sarcocystis-species-dna-in-the-heart-and-breast-muscles-of-rock-pigeons-columbia-livia
#5
Muhammad Mudasser Nazir, Muhammad Mazhar Ayaz, Atif Nisar Ahmed, Azhar Maqbool, Kamran Ashraf, Muhammad Oneeb, Ghulam Yasin, Atta Subhani, Muhammad Asif Ali, Noman Nazir, Muhammad Afzal Sajid
Little is known about the prevalence of protozoan parasites in the muscles of rock pigeons (Columbia livia) . The muscles from 54 (heart from 45 and breast from 54) rock pigeons were examined for DNA of Toxoplasma gondii , Neospora caninum, and Sarcocystis species using PCR. Twenty-four were female and 30 were males. The birds were part of flocks of pigeons housed at the tombs of saints in Lahore, Pakistan. Birds that died or were euthanized due to poor health were submitted for necropsy at the Department of Parasitology, University of Veterinary and Animal Sciences, Lahore, Pakistan, where DNA isolations and PCR were conducted...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29770229/sensitivity-of-different-cattle-breeds-to-the-infestation-of-cattle-ticks-amblyomma-variegatum-rhipicephalus-microplus-and-hyalomma-spp-on-the-natural-pastures-of-opkara-farm-benin
#6
Roland Eric Yessinou, Camus Adoligbe, Yao Akpo, Justin Adinci, Issaka Youssao Abdou Karim, Souaïbou Farougou
A study was carried out on the Opkara (Benin) cattle farm on 64 cattle of four different breeds (16 individuals per breed) from June to December 2016. During this study, three tick species were found in different numbers, Amblyomma variegatum (732), Rhipicephalus microplus (8079), and Hyalomma spp. (208), with parasitic intensity of 11.90, 126.23, and 3.25, respectively. The interracial comparison of the tick infestation between the cattle showed a significant difference ( P < 0.001). However, Girolando was more infested than all the cattle breeds...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29692928/a-novel-application-of-an-anthelmintic-mixture-for-use-against-gastrointestinal-parasites-of-red-deer-cervus-elaphus
#7
P L Hughes
A mixture of proprietary anthelmintics delivering 0.5 mg/kg moxidectin, 9.06 mg/kg oxfendazole, 15 mg/kg levamisole, and 0.08 mg/kg selenium on bodyweight basis per os to red deer is investigated. On a deer farm with a history of parasite problems, six weaner red deer were treated orally with a 50/50 mixture of Exodus Pour-On and Oxfen C Plus (Ex/Ox) at a dose rate of 1 ml/5 kg bodyweight. Six herd mates were untreated. Eleven days later abomasal worm counts for the untreated deer revealed an arithmetic mean burden of 2,566 Ostertagia -type worms and 300 Trichostrongylus axei ...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29666698/prevalence-of-intestinal-parasites-and-associated-factors-among-pulmonary-tuberculosis-suspected-patients-attending-university-of-gondar-hospital-gondar-northwest-ethiopia
#8
Yalewayker Tegegne, Tadelo Wondmagegn, Ligabaw Worku, Ayalew Jejaw Zeleke
Introduction: Intestinal parasitic infections are among the major public health problems in developing countries. Hence, it is significant to explore coinfection with intestinal parasites and pulmonary tuberculosis because coinfection increases the complexity of control and prevention of pulmonary tuberculosis and parasitic diseases. Objective: To assess the prevalence of intestinal parasites among pulmonary tuberculosis suspected patients. Method: Institutional based cross-sectional study was conducted at University of Gondar Hospital from March to May, 2017...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29610679/low-il-6-il-10-and-tnf-%C3%AE-and-high-il-13-cytokine-levels-are-associated-with-severe-hepatic-fibrosis-in-schistosoma-mansoni-chronically-exposed-individuals
#9
Mable M Mutengo, Takafira Mduluza, Paul Kelly, James C L Mwansa, Geoffrey Kwenda, Patrick Musonda, James Chipeta
Several studies have attributed the etiopathogenesis of chronic Schistosoma mansoni related hepatic fibrosis to unregulated immune responses against trapped parasite ova in the host. However, there is limited data on immune profiles associated with varying degrees of the disease in a population under chronic exposure to the parasite. We therefore investigated the role of selected T-helper (Th)1, Th2, and Th17 cytokines in relation to hepatic fibrosis severity among individuals resident in a hyper- Schistosoma mansoni endemic region of Western Zambia...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29593896/enteroparasites-in-riverside-settlements-in-the-pantanal-wetlands-ecosystem
#10
Patrícia Vieira da Silva, Lucimare Dos Santos Maciel, Ludiele Souza Castro, Paula Guerra Murat, Minoru German Higa Junior, Patrícia Honorato Zerlotti, Ana Rita Coimbra Motta-Castro, Elenir Rose Jardim Cury Pontes, Maria Elizabeth Cavalheiros Dorval
Background: Intestinal parasites are a major source of health problems in developing countries, where socioeconomic, cultural, and environmental conditions contribute in maintaining the biological cycles of various parasites and facilitating their spread. The objective of this study, conducted in Corumbá, Mato Grosso do Sul state, Brazil, was to investigate the occurrence of intestinal parasites in riverside communities in the South Pantanal wetlands and conduct educational interventions focused on health and environmental preservation...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29593895/cross-sectional-serological-survey-of-human-fascioliasis-in-canutama-municipality-in-western-amazon-brazil
#11
Marcel Gonçalves Maciel, Walter Dos Santos Lima, Francisco Lazaro Moreira de Almeida, Leila Inês Aguiar Raposo Câmara Coelho, Guilherme Alfredo Novelino Araújo, Mariana Gomes Lima, Luiz Henrique Gonçalves Maciel, Cíntia Aparecida de Jesus Pereira, Thaís Costa da Silva Maciel, Jorge Augusto de Oliveira Guerra, Rosa Amélia Gonçalves Santana, Maria das Graças Vale Barbosa Guerra
Background: Fascioliasis is an important parasitic disease. In the northern region of Brazil, a human parasite infection has been reported through a coprological survey. Eggs of Fasciola hepatica were found in fecal samples of 11 individuals. Knowledge of the infection in animals or the presence of snails is necessary to address the possibility of the parasite cycle occurrence in that region. The aim of this study was to describe the transmission of human fascioliasis in Canutama, Amazonas, in Western Amazonia, Brazil...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29568648/barriers-to-diagnosis-access-for-chagas-disease-in-colombia
#12
Mario Javier Olivera, Julián Felipe Porras Villamil, Christian Camilo Toquica Gahona, Jorge Martín Rodríguez Hernández
Chagas disease is the leading cause of nonischemic cardiomyopathy in Latin America. Timely access to diagnosis and trypanocidal treatment and preventive tools for millions of infected people continues to be a challenge. The purpose of this study was to identify potential barriers for the diagnosis of Chagas disease in Colombia from the perspective of healthcare providers. Using a simultaneous mixed-methods study design, we analyzed trends in access to screening and diagnosis for Chagas disease in Colombia and assessed the national barriers to access...
2018: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29410911/performance-of-laboratory-professionals-working-on-malaria-microscopy-in-tigray-north-ethiopia
#13
Megbaru Alemu, Desalegn Tadesse, Tesfaye Hailu, Wondemagegn Mulu, Awoke Derbie, Tadesse Hailu, Bayeh Abera
Background: Microscopic analysis of stained blood smear is the most suitable method of malaria diagnosis. However, gaps were observed among clinical laboratory professionals in microscopic diagnosis of malaria. Methods: A cross-sectional study was conducted in December 2015 among 46 laboratory professionals. Data was collected via on-site assessment and panel testing. The slide panel testing was composed of positive and negative slides. The kappa score was used to estimate the agreement between participants and reference reader...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29391947/-in-vivo-antimalarial-activity-of-the-solvent-fractions-of-fruit-rind-and-root-of-carica-papaya-linn-caricaceae-against-plasmodium-berghei-in-mice
#14
Gemechu Zeleke, Dereje Kebebe, Eshetu Mulisa, Fanta Gashe
Background: Currently, antimalarial drug resistance poses a serious challenge. This stresses the need for newer antimalarial compounds. Carica papaya is used traditionally and showed in vitro antimalarial activity. This study attempted to evaluate in vivo antimalarial activity of C. papaya in mice. Methods: In vivo antimalarial activity of solvent fractions of the plant was carried out against early P. berghei infection in mice. Parasitemia, temperature, PCV, and body weight of mice were recorded...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29379651/intra-abdominal-hydatid-cyst-sociodemographics-clinical-profiles-and-outcomes-of-patients-operated-on-at-a-tertiary-hospital-in-addis-ababa-ethiopia
#15
Engida Abebe, Temesgen Kassa, Mahteme Bekele, Ayelign Tsehay
Background: Hydatid cyst is caused by the tapeworm Echinococcus granulosus . The abdomen, specifically the liver, is the most common site affected. Objective: Determine the presentation patterns, types of surgical management, and outcomes of patients operated for intra-abdominal hydatid cyst (IAHC). Methodology: A retrospective descriptive study of patients admitted and operated for IAHC from September 1, 2011, to August 31, 2015. Results: Forty-two patients whose age ranged from 10 to 65 (mean of 37 years) were operated on...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29362672/frequency-of-toxocariasis-among-patients-clinically-suspected-to-have-visceral-toxocariasis-a-retrospective-descriptive-study-in-sri-lanka
#16
Devika Iddawela, Kiruthiha Ehambaram, Dhilma Atapattu, Kalyani Pethiyagoda, Lakmalee Bandara
Introduction: Human toxocariasis is caused by several species of the nematode Toxocara . Two common clinical syndromes are ocular and visceral larva migrans. Objectives: To determine the Toxocara antibody positivity in clinically suspected VLM patients and to describe demographic factors and clinical manifestations of seropositive patients. Methods: 522 clinically suspected patients were studied between 1993 and 2014. Relevant data was gathered from referral letters...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29318036/-cysticercus-fasciolaris-in-brown-rats-rattus-norvegicus-in-grenada-west-indies
#17
Ravindra Sharma, Keshaw Tiwari, Kristen Birmingham, Elan Armstrong, Andrea Montanez, Reneka Guy, Yvette Sepulveda, Veronica Mapp-Alexander, Claude DeAllie
Cat is the definitive host of Taenia taeniaeformis (T. taeniaeformis). Cysticercus fasciolaris (C. fasciolaris), the larval stage of T . taeniaeformis, develops in small rodents which act as intermediate host. The aim of this study was to estimate the prevalence of C. fasciolaris in brown rats (Rattus norvegicus) in the densely human populated parishes, St. George's and St. David's of Grenada, West Indies. One hundred and seventy rats were trapped near the residential areas from May to July, 2017 and examined for C...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29250439/the-effect-of-deworming-using-triple-dose-albendazole-on-nutritional-status-of-children-in-perobatang-village-southwest-sumba-indonesia
#18
Saleha Sungkar, Asri S Ridwan, Gladys Kusumowidagdo
High prevalence of STH leads to malnutrition, anemia, cognitive impairment, and growth disorders. Triple-dose albendazole 400 mg is a broad-spectrum anthelminthic; however, its effectiveness varies in every region. This study aims to determine the benefits of deworming using triple-dose albendazole on children's nutritional status in Perobatang Village, Southwest Sumba, Indonesia. This pre-post study was conducted in July 2016 and January 2017. Children aged 1-15 years were asked to collect stool for diagnosis of STH infection (Kato-Katz method), were measured for anthropometry status to obtain the nutritional status, and took albendazole 400 mg for three consecutive days...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29238615/profile-of-geohelminth-eggs-cysts-and-oocysts-of-protozoans-contaminating-the-soils-of-ten-primary-schools-in-dschang-west-cameroon
#19
Vanessa Rosine Nkouayep, Blandine Ngatou Tchakounté, Josué Wabo Poné
Helminthiasis and protozoans infections have been recognized as an important public health problem. The aim of the present study was to screen soil samples collected from 10 primary schools in the city of Dschang for the presence of soil-transmitted helminth eggs, cysts, and oocysts of protozoans. A total of 400 soil samples were collected around latrines, at playgrounds, and behind classrooms in each school. These samples were examined using the sucrose flotation method. From the result obtained, an overall contamination rate of 7...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29225962/tlr-specific-immune-responses-against-helminth-infections
#20
REVIEW
Sivaprakasam Rajasekaran, Rajamanickam Anuradha, Ramalingam Bethunaickan
Despite marked improvement in the quality of lives across the globe, more than 2 million individuals in socioeconomically disadvantaged environments remain infected by helminth (worm) parasites. Owing to the longevity of the worms and paucity of immunologic controls, these parasites survive for long periods within the bloodstream, lymphatics, and gastrointestinal tract resulting in pathologic conditions such as anemia, cirrhosis, and lymphatic filariasis. Despite infection, an asymptomatic state may be maintained by the host immunoregulatory environment, which involves multiple levels of regulatory cells and cytokines; a breakdown of this regulation is observed in pathological disease...
2017: Journal of Parasitology Research
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