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Journal of Investigative and Clinical Dentistry

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https://www.readbyqxmd.com/read/28631896/boric-acid-gel-as-local-drug-delivery-in-the-treatment-of-class-ii-furcation-defects-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#1
Sandeep Singhal, Avani Raju Pradeep, Dharmendra Kanoriya, Shruti Garg, Vibhuti Garg
AIM: Boric acid (BA) exhibits antibacterial, anti-inflammatory, as well as osteoblastic, activity. The aim of the present study was to explore the efficacy of 0.75% BA gel as a local drug-delivery system in adjunct to scaling and root planing (SRP) for the treatment of class II furcation defects in comparison with placebo gel. METHODS: A total of 48 mandibular class II furcation defects were randomized and treated with either 0.75% BA gel or placebo gel. Clinical parameters were recorded at baseline, 3 months, and 6 months, while radiographic parameters were recorded at baseline and 6 months...
June 20, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28631891/no-detectable-human-herpesvirus-8-oral-shedding-in-seronegative-healthy-immunocompetent-individuals-from-non-endemic-regions-for-kaposi-s-sarcoma-a-pilot-study
#2
Tânia R Tozetto-Mendoza, Laura M Sumita, Michelle Palmieri, Mariana Ornaghi, Alan M do Canto, Paulo H Braz-Silva
AIM: Saliva can play an important role in human herpesvirus-8 (HHV-8) transmission in endemic regions for Kaposi's sarcoma (KS). Little is known about HHV-8 oral shedding in immunocompetent individuals from non-endemic regions for KS. METHODS: We conducted a prospective study of HHV-8 salivary excretion among 59 healthy, immunocompetent individuals from São Paulo, Brazil, followed up weekly for 4 months, resulting in 16 saliva samples from each participant. Antibodies to HHV-8 latency-associated nuclear antigen (LANA) and lytic-phase antigens were investigated with immunofluorescence assays (IFA)...
June 20, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28631885/reliability-and-validity-of-fluorecam-for-white-spot-lesion-detection-an-in-vitro-study
#3
Moufida Abufarwa, Amal Noureldin, Phillip M Campbell, Peter H Buschang
AIM: In the present study, we tested the reliability and validity of a new light fluorescence device, the FluoreCam. METHODS: Twenty-five human teeth were sectioned mesiodistally into halves. Group 1 (n=30) included specimens with either sound enamel or natural white-spot lesions (WSL). Group 2 (n=20) included specimens with sound enamel used to create artificial WSL. Using the FluoreCam, baseline scans of enamel surfaces were obtained under standardized conditions...
June 20, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28608463/effect-of-etching-on-bonding-of-a-self-etch-adhesive-to-dentine-affected-by-amelogenesis-imperfecta
#4
Don Jeevanie Epasinghe, Cynthia Kar Yung Yiu
AIM: Dentine affected by amelogenesis imperfecta (AI) is histologically altered due to loss of hypoplastic enamel and becomes hypermineralized. In the present study, we examined the effect of additional acid etching on microtensile bond strength of a self-etch adhesive to AI-affected dentine. METHODS: Flat coronal dentine obtained from extracted AI-affected and non-carious permanent molars were allocated to two groups: (a) Clearfil SE Bond (control); and (b) Clearfil SE Bond and additional etching with 34% phosphoric acid for 15 seconds...
June 13, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28544729/comparative-study-of-two-chemical-protocols-for-creating-white-spot-lesions-an-in-vitro-fluorecam-evaluation
#5
Moufida Abufarwa, Amal Noureldin, Phillip M Campbell, Peter H Buschang
AIM: The aim of the present study was to compare the effectiveness and practicality of two commonly-used protocols for white spot lesion creation. METHODS: Sound posterior human teeth were sectioned into halves and randomly allocated into two groups (n=20). Using the FluoreCam system, the enamel surfaces were imaged under standardized conditions, and baseline data (area, intensity, and impact) were recorded. Specimens were covered with an acid-resistant polish, leaving a 2×6-mm enamel window...
May 23, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28544653/minimally-invasive-dental-anesthesia-patients-preferences-and-analysis-of-the-willingness-to-pay-index
#6
Dino Re, Massimo Del Fabbro, Lorena Karanxha, Gabriele Augusti, Davide Augusti, Sabrine Fessi, Silvio Taschieri
AIM: The aim of the present prospective study was to evaluate the impact of a computer-controlled anesthesia on patients' comfort and to investigate, through the willingness-to-pay (WTP) index, and patients' acceptance of this new technology. METHODS: Fifty patients undergoing a class I or II restorative procedure were enrolled. A computer-controlled device for anesthetic delivery was utilized, and a questionnaire on the level of discomfort and WTP was given to all patients...
May 23, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28497901/risk-factors-of-periodontal-disease-in-vietnamese-patients
#7
Thuy A V Pham, Thoai Q Kieu, Lan T Q Ngo
AIM: The aim of the present study was to assess the association of periodontitis with dental and smoking behaviors, self-perception of oral status, dental knowledge, and obesity in Vietnamese patients. METHODS: A cross-sectional study was conducted on 367 adults who first visited the Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Information on demographic characteristics, dental and smoking behaviors, self-perception of oral status, dental knowledge, and nutritional status was investigated by a self-administered questionnaire...
May 12, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28480637/photodynamic-treatment-outcomes-of-potentially-malignant-lesions-and-malignancies-of-the-head-and-neck-region-a-systematic-review
#8
Shailesh M Gondivkar, Amol Ramchandra Gadbail, Manjari G Choudhary, Priyanka R Vedpathak, Manoj S Likhitkar
AIM: The aim of the present study was to systematically review the efficacy of photodynamic therapy (PDT) in the management of oral potentially-malignant disorders (PMDS) and head and neck squamous cell carcinoma (HNSCC). METHODS: From 1985 to 2015, PubMed/Medline, Google Scholar, EMBASE, and ISI Web of Knowledge were searched using different combinations of the following key words: PDT, oral precancer, leukoplakia, erythroplakia, erythroleukoplakia, verrucous hyperplasia, oral submucous fibrosis, and HNSCC...
May 8, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28474492/vertical-root-fractures-in-endodontically-treated-teeth-a%C3%A2-retrospective-analysis-of-possible-risk-factors
#9
Claudia García-Guerrero, Claudia Parra-Junco, Sara Quijano-Guauque, Nicolás Molano, Gerardo A Pineda, Dairo J Marín-Zuluaga
AIM: The prevalence of vertical root fractures (VRF) ranges from 2% to 20%, and is associated with endodontically-treated teeth (ETT). The aim of the present study was to analyze clinically and radiographically, at different intervals of time, some of the risk factors present in ETT that developed VRF. METHODS: A classification model according to time measured the follow-up period of three groups. A match was made for times of occurrence (cases) and follow up (controls)...
May 5, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28474437/clinical-efficacy-of-subgingivally-delivered-0-75-boric-acid-gel-as-an-adjunct-to-mechanotherapy-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#10
Dharmendra Kanoriya, Sandeep Singhal, Vibhuti Garg, Avani R Pradeep, Shruti Garg, Amit Kumar
AIM: Borinic acid quinoline esters are a recently-identified class of new antibacterial and anti-inflammatory compounds known to inhibit osteoclastic bone resorption. They have proposed to have osteostimulative properties by causing osteoblast differentiation in vivo and in vitro. The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of the subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic parameters, and compare this method with SRP plus placebo gel alone in chronic periodontitis (CP) patients...
May 5, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28419770/pilot-survey-of-the-health-of-massachusetts-dentists
#11
Romesh P Nalliah, Alan Budd, Veerasathpurush Allareddy
AIM: Dentistry is a career that is very rewarding because of the direct opportunity to deliver essential health services to patients in need. Dentistry is also very demanding; mentally, physically, and even emotionally. Little is known about the health of dentists and how it compares to the health of the general population. The aim of the present study was to report on the general health and health practices of dentists in Massachusetts. METHODS: A medical health and health practices survey was developed from the Delaware Valley Community Health Center and customized...
April 16, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28393469/gingival-profiles-in-a-select-asian-cohort-a-pilot-study
#12
Wan Zhen Lee, Marianne M A Ong, Alvin B-K Yeo
AIM: The aim of the present study was to determine the facial gingival profiles of teeth with a healthy periodontium in an Asian population. METHODS: A total of 51 patients with a healthy periodontium were examined. Gingival thickness (GT) and gingival width (GW) were assessed at the maxillary and mandibular incisors to the first molars. GT was measured by transgingival probing (GT-TGP), and probe visibility through the marginal gingiva (GT-TRAN) was assessed. Results between groups (anterior and posterior, tooth types) were analyzed using one-way analysis of variance and t-test...
April 10, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28387048/genetic-basis-of-dentigerous-cysts-associated-with-supernumerary-teeth-a-narrative-review
#13
REVIEW
Robert P Anthonappa, Manikandan Ekambaram, Chaturi N G Neboda, Nigel M King, Abu-Bakr M Rabie
In the present study, we sought to: (a) analyze the p53 gene status in dentigerous cysts (DC) associated with supernumerary teeth (ST) in a pair of siblings with ST, of whom one developed a DC; and (b) conduct a narrative review of the literature on ST associated with DC. Blood samples were obtained, and the isolated DNA was used to amplify exons 4-8 of the p53 gene using specific primers, and subsequently sequenced. No mutations were identified in the coding regions of the p53 gene. A review of the literature revealed a prevalence of DC associated with ST to be as high as 13...
April 6, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28386989/predictors-of-oral-health-related-quality-of-life-in-iranian-adolescents-a-prospective-study
#14
Amir H Pakpour, Chung-Ying Lin, Santhosh Kumar, Bengt Fridlund, Henrik Jansson
AIM: In the present study, we evaluated the direct and mediating (indirect) effects of clinical oral conditions, dental anxiety, sense of coherence (SOC), and socioeconomic variables on oral health-related quality of life (OHRQoL) and general health-related quality of life (GHRQoL) in Iranian adolescents. METHODS: A longitudinal design was used with a sample of 1052 (694 males, mean age=15.05 years) schoolchildren from Qazvin, Iran. Each participant completed a background information sheet and the following scales at baseline: Modified Dental Anxiety Scale, SOC, PedsQL 4...
April 6, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28371484/awareness-of-risk-of-cross-infection-and-infection-control-measures-among-patients-attending-university-dental-hospital-peradeniya-sri-lanka
#15
Dilini Ratnayake, Sumudu Medawela, Ruwan Jayasinghe, Sumedha Jayathilake, Dileep de Silva, Mohaideen Sitheeque
AIM: The aim of the present study was to assess awareness of the risk of cross-infection and infection-control measures practiced in dental clinics for patients attending the outpatient dental department (OPD) at University Dental Hospital, Peradeniya, Sri Lanka. METHODS: A descriptive cross-sectional study was carried out among 427 patients who attended the OPD clinics at University Dental Hospital. An interviewer-administered questionnaire was used to collect data, and chi-squared-test of association was applied where appropriate...
March 31, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/26997329/tooth-enamel-properties-and-morphology-after-microabrasion-an-in-situ-study
#16
Núbia Inocencya Pavesi Pini, Débora Alves Nunes Leite Lima, Renato Herman Sundfeld, Gláucia Maria Bovi Ambrosano, Flavio Henrique Baggio Aguiar, José Roberto Lovadino
AIM: This study evaluated the effect of saliva on enamel after microabrasion with different microabrasive compounds under in situ conditions. METHODS: Enamel/dentin blocks (16 mm(2) ) from bovine incisors were divided into nine groups (n = 19): one control group (no treatment), four groups treated with microabrasion using 35% phosphoric acid (H3 PO4 ) + pumice, and the last four groups treated with microabrasion using 6.6% hydrochloric acid (HCl) + silica. The treated groups were subdivided according to the in situ regimen: without salivary exposure, 1 h, 24 h, or 7 days of saliva exposure...
May 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/26991690/cellular-cannibalism-in-giant-cells-of-central-giant-cell-granuloma-of-jaw-bones-and-giant-cell-tumors-of-long-bones
#17
Gargi S Sarode, Sachin C Sarode, Shailesh Gawande, Snehal Patil, Rahul Anand, Shankar Gouda Patil, Prakash Patil
AIM: The aim of the present study was to investigate the relationship of central giant cell granuloma (CGCG) and giant cell tumor of long bones (GCT) with respect to cannibalistic giant cells (GCs). METHOD: Sixteen cases each of CGCG and GCT were histopathologically analyzed for cannibalistic GCs. One hundred GCs were examined in each section, and the number of cannibalistic GCs was expressed in percentage. RESULTS: Cannibalistic GCs were seen in all cases of CGCG and GCT (100%)...
May 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/26991538/denture-induced-stomatitis-and-associated-factors-in-a-group-of-patients-attending-a-university-dental-hospital-in-sri-lanka
#18
Indika P Thilakumara, Jayalath A M S Jayatilake, Ranjith W Pallegama, Arjuna N B Ellepola
AIM: The aim of the present study was to investigate factors associated with denture-induced stomatitis (DIS) among denture wearers and their oral and hand carriage of Candida. METHODS: Sociodemographics and denture and oral hygiene practices were investigated using an interviewer-administered questionnaire in denture wearers with DIS (n = 60) and without DIS (n = 60) selected using a convenience sampling of patients attending the Department of Prosthetic Dentistry, University of Peradeniya, Sri Lanka...
May 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/26988864/subgingivally-delivered-1-2-atorvastatin-in-the-treatment-of-chronic-periodontitis-among-smokers-a-randomized-controlled-clinical-trial
#19
Minal Kumari, Santosh S Martande, Avani R Pradeep
AIM: Statins are known to have a beneficial effect in the treatment of chronic periodontitis (CP). The current study was designed to investigate the effectiveness of a 1.2% atorvastatin (ATV) local drug delivery system as an adjunct to scaling and root planing (SRP) in the treatment of intrabony defects (IBD) in CP among smokers. METHODS: Seventy-one smokers with CP were categorized into two treatment groups: SRP + 1.2% ATV gel and SRP + placebo gel. Clinical parameters, modified sulcus bleeding index, probing depth, and clinical attachment level were recorded at baseline before SRP and at 3, 6, and 9 months...
May 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/26840561/antifibrotic-effect-of-centella-asiatica-linn-and-asiatic-acid-on-arecoline-induced-fibrosis-in-human-buccal-fibroblasts
#20
Pooja Narain Adtani, Malathi Narasimhan, Alan M Punnoose, Himavanth Reddy Kambalachenu
AIM: The aim of the present study was to investigate the in vitro antifibrogenic effects of Centella asiatica Linn (CA) and its bioactive triterpene aglycone asiatic acid (AA) on arecoline-induced fibrosis in primary human buccal fibroblasts (HBF). METHODS: An ethanolic extract of CA was prepared, and AA was purchased commercially. High-performance thin-layer chromatography (HPTLC) was performed to quantify AA in the CA extract; colorimetric assay (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) was performed to determine an half-maximal inhibitory concentration...
May 2017: Journal of Investigative and Clinical Dentistry
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