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Journal of Investigative and Clinical Dentistry

Haruka Kon, Hiroshi Kobayashi, Naoki Sakurai, Kiyoshi Watanabe, Yoshiro Yamaga, Takahiro Ono
AIM: The aim of the present study was to clarify differences between personal computer (PC)/mobile device combination and PC-only user patterns. We analyzed access frequency and time spent on a complete denture preclinical website in order to maximize website effectiveness. METHODS: Fourth-year undergraduate students (N=41) in the preclinical complete denture laboratory course were invited to participate in this survey during the final week of the course to track login data...
November 15, 2016: Journal of Investigative and Clinical Dentistry
Sunil Babu Kotha, Ravikumar Ramakrishnaiah, Darshan Devang Divakar, Sree Lalita Celur, Saad Qasim, Jukka P Matinlinna
AIM: The aim of the present study was to evaluate the effect of chemical disinfection, autoclave, and microwave sterilization on some of the key properties of elastomers. METHODS: Five polyvinylsiloxane elastomeric impression materials were evaluated. Forty samples were fabricated from each material. The samples were randomly selected and assigned to four experimental groups with 50 samples each: group I, control; group II,chemical disinfection; group III, autoclave sterilization; and group IV, microwave sterilization...
October 26, 2016: Journal of Investigative and Clinical Dentistry
D Sharathkumar Sanketh, Samuel Raj Srinivasan, Shankargouda Patil, Kannan Ranganathan
AIM: In the present study, we simulated clinical scenarios by explicitly describing the history and clinical and histological features of hypothetical patients presenting with oral lichen planus (OLP), oral lichenoid lesion, and epithelial dysplasia in a self-designed questionnaire. By doing so, we aimed to elicit a diagnosis from oral pathologists and trainees, analyze their responses, appraise issues, and propose solutions regarding the diagnosis of OLP. METHODS: The questionnaire was distributed to 100 oral pathologists and trainees in South India...
October 26, 2016: Journal of Investigative and Clinical Dentistry
Stefano Corbella, Roberto Weinstein, Luca Francetti, Silvio Taschieri, Massimo Del Fabbro
The aim of the present study was to systematically review the existing literature on periodontal regenerative procedures in individuals affected by aggressive periodontitis (AgP). An electronic and manual search was performed using an ad hoc prepared search string. All types of study designs were considered acceptable for inclusion. Data about treated patients, baseline clinical parameters, type of surgery, and outcomes were extracted and recorded. A narrative evaluation of the results was performed. After the article-selection process, a total of 22 full-texts were included in the qualitative synthesis...
October 25, 2016: Journal of Investigative and Clinical Dentistry
Ratilal Lalloo, Geetesh Solanki, Khabiso Ramphoma, Neil G Myburgh
AIM: In the present study, we assessed the patterns and types of antibiotics prescribed following tooth extractions, and the alignment of these practices with the evidence available. METHODS: The study used health insurance claim data from South African dental practitioners for 2013, analyzing the antibiotic prescribing patterns around tooth extractions, separately for four event types: exposed (simple) tooth extractions in: (a) healthy patients and (b) patients with chronic conditions; and impacted tooth extractions in (c) healthy patients and (d) patients with a chronic condition...
October 24, 2016: Journal of Investigative and Clinical Dentistry
Fawad Javed, Changyong Feng, Dorota T Kopycka-Kedzierawski
The aim was to systemically review the incidence of early childhood caries (ECC). The addressed focused question was "What is the reported incidence of ECC?" Indexed databases were searched using various key words. Five studies were included and processed for data extraction. All studies were prospective and two studies were randomized clinical trials. The number of participants ranged between 96 and 1275 children. Two studies reported the mean age of children, that ranged between 1.8 and 2.5 years (range 0...
September 29, 2016: Journal of Investigative and Clinical Dentistry
Josh D Silvertown, Bonny P Y Wong, Stephen H Abrams, Koneswaran S Sivagurunathan, Sapna M Mathews, Bennett T Amaechi
AIM: The aim of the present study was to investigate the ability of operators using The Canary System and DIAGNOdent to detect natural pit and fissure caries under four commonly-used opaque dental sealants. METHODS: Mixed sound and carious pits/fissures (N = 105) selected from 40 human teeth were randomly assigned (10 teeth/group) to one of four opaque sealant groups (Delton, Embrace WetBond, Helioseal F, UltraSeal XT Plus). Selected pits/fissures sites on occlusal surfaces were scanned with The Canary System and DIAGNOdent, sealed, re-scanned, and subjected to polarized light microscopy to confirm whether the scanned regions were sound or carious...
September 26, 2016: Journal of Investigative and Clinical Dentistry
Emi Inada, Issei Saitoh, Naoko Kubota, Miki Soda, Kazunari Matsueda, Tomoya Murakami, Tadashi Sawami, Akiko Kagoshima, Youichi Yamasaki, Masahiro Sato
AIM: The aim of the present study was to prove that primary cells enriched with stem cells are more easily reprogrammed to generate induced pluripotent stem (iPS) cells than those with scarce numbers of stem cells. METHODS: We surveyed the alkaline phosphatase (ALP) activity in five primarily-isolated human deciduous teeth-derived dental pulp cells (HDDPC) with cytochemical staining to examine the possible presence of stem cells. Next, the expression of stemness-specific factors, such as OCT(Octumer-binding transcription factor)3/4, NANOG, SOX2(SRY (sex determining region Y)-box 2), CD90, muscle segment homeodomain homeobox (MSX) 1, and MSX2, was assessed with a reverse transcription polymerase chain reaction method...
September 18, 2016: Journal of Investigative and Clinical Dentistry
Pilana Vithanage Kalani Shihanika Hettiarachchi, Ruvini Manjula Hettiarachchi, Ruwan Duminda Jayasinghe, Mohaideen Sitheeque
AIM: Oral lichen planus (OLP) is a common, chronic inflammatory disease of the oral mucosa. Although several studies have shown the efficacy of different treatment modalities, a definitive cure has not yet been established. The present trial compares the effectiveness of topically-applied clobetasol and tacrolimus in the symptomatic management of OLP. METHODS: A randomized, comparative, double-blind study with 68 patients (43 females, 25 males; mean age: 46.76 years) was undertaken...
September 15, 2016: Journal of Investigative and Clinical Dentistry
Shankargouda Patil, Saman Warnakulasuriya, Thirumal Raj, D S Sanketh, Roopa S Rao
OBJECTIVE: Exophytic oral verrucous hyperplasia (OVH) is a new entity described by an expert working group from South Asia. First reported in Taiwan, there are no reports so far from an Indian population. The aim was to use the microscopic features described by the expert group to differentiate OVH from other oral verruco-papillary lesions in an Indian archive. MATERIALS AND METHODS: In a retrospective multicentre study, using pathology archives, 188 verruco-papillary lesions were retrieved from pathology archives...
November 2016: Journal of Investigative and Clinical Dentistry
Hooman Sadrhaghighi, Afsaneh Zarghami, Shahrzad Sadrhaghighi, Mahsa Eskandarinezhad
AIM: In the present study, we sought to assess the esthetic perception and level of acceptability of variations in smile components, including dental midline, buccal corridor, vertical lip thickness, and the golden ratio, by orthodontists, general dentists, dental students, artists, and laypersons. METHODS: An attractive female smile was digitally manipulated with regard to four smile components: dental midline, buccal corridor, vertical lip thickness, and the golden ratio...
September 3, 2016: Journal of Investigative and Clinical Dentistry
Romesh P Nalliah, Michael S Forman, Sydnee E Chavis, Peggy Timothé
PURPOSE: The Commission of Dental Accreditation (CODA) does not set minimum standards for clock hours of training in Dental and Clinical sciences. The purpose of this evaluation was to compare United States (US) dental schools for variability in clock hours. The current paper utilizes the American Dental Association's survey of clock hours of all US dental schools which is publicly available data. Clock hours survey from 2010 to 2011 was utilized and the analysis tool, JMP, was utilized to visualize and report variability...
August 4, 2016: Journal of Investigative and Clinical Dentistry
Vaishnavi Sivasankar, Kannan Ranganathan
AIM: Dental pulp stem cells (DPSCs) in permanent teeth and stem cells from human exfoliated deciduous (SHED) teeth are unique sources of mesenchymal stem cells. The aim of this study was to compare the growth characteristics and morphology of DPSCs and SHED and their immuno-phenotype using CD73 and CD146 in the 1st, 3rd, and 5th passage of cell culture. METHODS: Growth characteristics, morphology, and colony forming efficiency were assessed for SHED and DPSCs. Immunocytochemistry and flow cytometry using CD146 and CD73 was performed for SHED and DPSCs in the 1st, 3rd and 5th passage of culture...
August 2016: Journal of Investigative and Clinical Dentistry
Luís Silva Monteiro, Saman Warnakulasuriya, Suzana Cadilhe, Duarte Sousa, Pedro Ferreira Trancoso, Luís Antunes, Filomena Salazar, José Júlio Pacheco
OBJECTIVE: To assess the awareness and knowledge on oral cancer in a general population of Oporto city, in Portugal. METHODS: Face-to-face interviews were performed with 1116 individuals, resident in the city of Oporto. Participants' socio-demographic information, lifestyle habits and awareness, knowledge and beliefs on oral cancer were ascertained. RESULTS: Breast cancer was the most mentioned being as heard of (69.8%), while oral cancer was one of the least heard of (23...
August 2016: Journal of Investigative and Clinical Dentistry
Abdul-Aziz Al-Sawai, Hussein Labib
The purpose of this systematic literature review was to compare the clinical performance between conventionally- (delayed) and immediately-loaded implants. A literature search of studies published between 1995 and 2012 was performed using several electronic databases and the following key words: "immediate loading", "dental implants", "immediate function", "early loading", "oral implants", "immediate restoration", and "systematic review" was performed. The electronic search was supplemented with hand-searching in dental journals and cross-referencing within the selected articles...
August 2016: Journal of Investigative and Clinical Dentistry
D S Sanketh, Shankargouda Patil, Roopa S Rao
OBJECTIVE: To determine the frequency of Candida in oral squamous cell carcinoma (OSCC) using Calcofluor White (CFW) fluorescent stain and to evaluate the association of the same in different grades of OSCC. METHODS: One hundred archival formalin fixed paraffin embedded tissues of diagnosed cases of OSCC were retrieved. The samples comprised of 81, 18 and 1 case of well, moderately, and poorly differentiated squamous cell carcinomas (WSCC, MSCC, PSCC) respectively...
August 2016: Journal of Investigative and Clinical Dentistry
Rabab A Ghanem, Mohammad Z Nassani, Kusai Baroudi, Amany Abdel Fattah
OBJECTIVE: The aim of this study was to compare the linear horizontal dimensional accuracy of the stone casts obtained from four different direct transfer implant impression techniques compared with an acrylic master model. METHODS: An acrylic resin master model with four implants was fabricated. Four impression techniques were used with squared transfer impression copings. These were nonsplinted transfer copings, splinted transfer copings, airborne particle-abraded transfer copings coated with impression adhesive, and transfer copings with unilateral acrylic extension...
August 2016: Journal of Investigative and Clinical Dentistry
Amy Wai-Yee Wong, Shinan Zhang, Cheng-Fei Zhang, Chun-Hung Chu
AIM: To study the preference of practice for single- and multiple-visit endodontic treatment by Hong Kong endodontists and general dental practitioners (GDPs), and to investigate their reasons for choosing single- or multiple-visit treatment in their practice. METHOD: An anonymous questionnaire was mailed to all 16 registered endodontists and 800 randomly selected GDPs in Hong Kong to explore their preference and reasons for selecting single- or multiple-visit endodontic treatment for their patients...
August 2016: Journal of Investigative and Clinical Dentistry
Prasanna Neelakantan, Pallavi Reddy, James L Gutmann
OBJECTIVE: To evaluate and compare the cyclic fatigue of a rotary (One Shape) and reciprocating (Reciproc) single file system in a simulated S-shaped canal in static and dynamic models. METHODS: The instruments (n = 50 per instrument) were tested in a custom-made device under static (n = 25) and dynamic loads (n = 25) to determine the number of cycles to fracture (NCF). The length of the fractured segments was also measured. Cyclic fatigue data were analyzed by one-way analysis of variance and Tukey honestly significantly different tests, while the data recorded for the fractured fragment lengths were compared using Student's t-test with the level of significance set at 0...
August 2016: Journal of Investigative and Clinical Dentistry
Swetha Paulose, Vishwanath Rangdhol, Ramasamy Ramesh, Siccandar Ali Jeelani, Sivakumar Brooklyin
AIM: To quantify the level of serum malondialdehyde and extent of DNA damage using comet assay in patients with oral submucous fibrosis (SMF) in comparison to normal individuals and to correlate the extent of DNA damage with MDA levels. METHODS: Study included 30 cases of SMF (n = 30) and equal number of healthy volunteers. Serum malondialdehyde was measured using the thiobarbituric-trichloroacetitic acid (TBA-TCA) method. Comet assay was used to assess the DNA damage...
August 2016: Journal of Investigative and Clinical Dentistry
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