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Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28546876/self-monitoring-symptoms-in-glaucoma-a-feasibility-study-of-a-web-based-diary-tool
#1
Leanne McDonald, Fiona C Glen, Deanna J Taylor, David P Crabb
Purpose. Glaucoma patients annually spend only a few hours in an eye clinic but spend more than 5000 waking hours engaged in everything else. We propose that patients could self-monitor changes in visual symptoms providing valuable between clinic information; we test the hypothesis that this is feasible using a web-based diary tool. Methods. Ten glaucoma patients with a range of visual field loss took part in an eight-week pilot study. After completing a series of baseline tests, volunteers were prompted to monitor symptoms every three days and complete a diary about their vision during daily life using a bespoke web-based diary tool...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28540083/additive-intraocular-pressure-lowering-effects-of-ripasudil-with-glaucoma-therapeutic-agents-in-rabbits-and-monkeys
#2
Yoshio Kaneko, Masayuki Ohta, Tomoyuki Isobe, Yuto Nakamura, Ken Mizuno
Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, is developed for the treatment of glaucoma and ocular hypertension. Topical administration of ripasudil decreases intraocular pressure (IOP) by increasing conventional outflow through the trabeculae to Schlemm's canal, which is different from existing agents that suppress aqueous humor production or promote uveoscleral outflow. In this study, we demonstrated that ripasudil significantly lowered IOP in combined regimens with other glaucoma therapeutic agents in rabbits and monkeys...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28540082/a-meta-analysis-comparing-postoperative-complications-and-outcomes-of-femtosecond-laser-assisted-cataract-surgery-versus-conventional-phacoemulsification-for-cataract
#3
REVIEW
Zi Ye, Zhaohui Li, Shouzhi He
Objective. This meta-analysis aimed to compare the outcomes and postoperative complications between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification cataract surgery (CPCS). Methods. Bibliographic databases, including PubMed, Embase, and Cochrane library, were systematically searched for references on or before September 2015 regarding the outcomes and complications by FLACS or CPCS. Data on corneal endothelial cell loss, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive outcomes, and postoperative complications were retrieved...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28540081/a-system-review-and-meta-analysis-of-canaloplasty-outcomes-in-glaucoma-treatment-in-comparison-with-trabeculectomy
#4
REVIEW
Bing Zhang, Jie Kang, Xiaoming Chen
Purpose. This system review studied the efficiency and safety of canaloplasty (CP) and compared the outcomes between CP and trabeculectomy (TE). Methods. Literatures were searched in PubMed and EMBASE. The meta-analysis was conducted on the postoperative outcomes in CP and then on the differences of outcomes between CP and TE. Results. In the meta-analysis, IOP decreased by 9.94 (95% CI 8.42 to 11.45) mmHg with an average AGM reduction of 2.11 (95% CI 1.80 to 2.42) one year after CP. The IOP reduction was significantly higher after TE than after CP, with an average difference of 3...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28512581/refractive-lens-exchange-combined-with-primary-posterior-vitrectorhexis-in-highly-myopic-patients
#5
Tarek A Mohamed, Wael Soliman, Dalia M El Sebaity, Ahmed M Fathalla
Purpose. To evaluate efficacy and safety of primary vitrectorhexis for posterior capsulotomy in highly myopic patients undergoing refractive lens exchange. Methods. The study is a prospective nonrandomized interventional study. The study comprised 60 eyes of 60 myopic patients. All patients underwent refractive lens exchange (RLE) and foldable IOL implantation combined with primary posterior capsulotomy. We used a 23-gauge vitrectomy probe for the creation of the posterior capsule opening. We followed the patients for one year...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28512580/high-intensity-focused-ultrasound-circular-cyclocoagulation-in-glaucoma-a-step-forward-for-cyclodestruction
#6
REVIEW
Rodolfo Mastropasqua, Vincenzo Fasanella, Alessandra Mastropasqua, Marco Ciancaglini, Luca Agnifili
The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect relationship. These drawbacks limited the application of cyclodestructive procedures almost exclusively to refractory glaucoma. High-intensity focused ultrasound (HIFU), proposed in the early 1980s and later abandoned because of the complexity and side effects of the procedure, was recently reconsidered in a new approach to destroy the ciliary body...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28512579/the-impact-of-electronic-reading-devices-on-reading-speed-and-comfort-in-patients-with-decreased-vision
#7
Henry L Feng, Daniel B Roth, Howard F Fine, Jonathan L Prenner, Kunjal K Modi, William J Feuer
Background/Aims. To evaluate the impact of back-illuminated and nonilluminated electronic reading devices on reading speed and comfort in patients with decreased vision. Methods. A prospective study involving a convenience sample of 167 patients at a single retina practice from January 2011 to December 2012. Participants were asked to read five different excerpts on five different media in a randomly assigned order. Media included a printed book at 12-point font (12PF), iPad2 at 12PF, iPad2 at 18-point font (18PF), Kindle2 at 12PF, and Kindle2 at 18PF...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28512578/safety-and-efficacy-of-microinvasive-glaucoma-surgery
#8
REVIEW
David Z Chen, Chelvin C A Sng
Microinvasive glaucoma surgery (MIGS) is emerging as a new therapeutic option for glaucoma patients who wish to reduce their medication burden and avoid the postoperative complications of conventional glaucoma filtration surgery. These devices differ in terms of their efficacy and safety profile. Schlemm's canal devices have the most favorable safety profile at the compromise of modest efficacy, while subconjunctival and suprachoroidal devices are potentially more effective at lowering the intraocular pressure at the expense of a higher rate of complications...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491473/clinical-analysis-of-ocular-parameters-contributing-to-intraoperative-pain-during-standard-phacoemulsification
#9
Yong Koo Kang, Myung Jun Kim, Hong Kyun Kim, Bo Young Chun
Purpose. To study the correlation between ocular parameters and subjective pain that patients perceived during phacoemulsification. Methods. Medical records of 142 patients who underwent standard phacoemulsification under topical anesthesia between March and August 2016 were retrospectively reviewed. The pain during phacoemulsification and 1 h after surgery was assessed and compared using a visual analog scale. In addition, demographic data, preoperative biometric parameters, and intraoperative surgical parameters were recorded...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491472/the-effect-of-corneal-refractive-surgery-on-glaucoma
#10
REVIEW
Vassilios Kozobolis, Aristeidis Konstantinidis, Haris Sideroudi, G Labiris
Laser-assisted refractive procedures have become very popular in the last two decades. As a result, a "generation" of patients with altered corneal properties is emerging. These patients will require both cataract extraction and glaucoma follow-up in the future. Since the glaucoma examination largely depends on the corneal properties, the reshaped postrefractive surgery cornea poses a challenge in the diagnosis, follow-up, and management of the glaucomatous patient. In order to overcome this problem, every patient who is planned to undergo corneal refractive surgery must have a thorough glaucoma examination in order for the ophthalmologist to be able to monitor their patients for possible glaucoma development and/or progression...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491471/a-novel-three-dimensional-vector-analysis-of-axial-globe-position-in-thyroid-eye-disease
#11
Jie Guo, Jiang Qian, Yifei Yuan, Rui Zhang, Wenhu Huang
Purpose. To define a three-dimensional (3D) vector method to describe the axial globe position in thyroid eye disease (TED). Methods. CT data from 59 patients with TED were collected and 3D images were reconstructed. A reference coordinate system was established, and the coordinates of the corneal apex and the eyeball center were calculated to obtain the globe vector [Formula: see text]. The measurement reliability was evaluated. The parameters of [Formula: see text] were analyzed and compared with the results of two-dimensional (2D) CT measurement, Hertel exophthalmometry, and strabismus tests...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491470/effect-of-active-and-passive-smoking-on-retinal-nerve-fibre-layer-and-ganglion-cell-complex
#12
Amany Abd El-Fattah El-Shazly, Yousra Ahmed Thabet Farweez, Lamia Salah Elewa, Yasser Abdelmageuid Elzankalony, Botheina Ahmed Thabet Farweez
Aim. To evaluate the possible structural and functional changes in the retinal nerve fibre layer (RNFL) and the ganglion cell complex (GCC) of chronic smokers and compare them with those of passive healthy smokers using spectral domain optical coherence tomography (SD-OCT) and pattern electroretinogram (PERG). Materials and Methods. We include 80 active chronic smokers and 80 age- and sex-matched healthy passive smokers. After a full ophthalmological examination, SD-OCT and PERG were tested for all participants...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491469/novel-diagnostic-and-therapeutic-methods-in-ocular-surface-and-corneal-diseases
#13
EDITORIAL
Anna K Nowinska, László Módis, Robert Koprowski, Jesús Merayo-Lloves
No abstract text is available yet for this article.
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491468/recurrence-of-retinopathy-of-prematurity-in-zone-ii-stage-3-after-ranibizumab-treatment-a-retrospective-study
#14
Qinrui Hu, Yujing Bai, Xiaoli Chen, Lvzhen Huang, Yi Chen, Xiaoxin Li
Objective. To determine the prevalence and risk factors for the recurrence of retinopathy of prematurity (ROP) in Zone II Stage 3+ after ranibizumab treatment. Methods. This was a retrospective, nonrandomized, noncontrolled study that excluded Zone I and aggressive posterior ROP (APROP) cases. Infants who developed Zone II Stage 3 ROP with plus disease and underwent initial intravitreal injection of ranibizumab (IVR) were recruited. Patients were divided into 2 groups based on the outcome after initial ranibizumab treatment: recurrence of ROP or favorable outcome...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491467/association-between-asymptomatic-unilateral-internal-carotid-artery-stenosis-and-electrophysiological-function-of-the-retina-and-optic-nerve
#15
Anna Machalińska, Aleksandra Kowalska-Budek, Miłosz Piotr Kawa, Arkadiusz Kazimierczak, Krzysztof Safranow, Marta Kirkiewicz, Grażyna Wilk, Wojciech Lubiński, Piotr Gutowski, Bogusław Machaliński
Purpose. This study was designed to assess retinal and optic nerve bioelectrical function in patients with unilateral asymptomatic but hemodynamically significant internal carotid artery stenosis (ICAS). Methods. Forty-two subjects with a diagnosis of unilateral ICAS and 34 controls were analyzed. Full-field electroretinogram (ERG), pattern electroretinogram (PERG), and pattern visual-evoked potentials, as well as optical coherence tomography and ophthalmological examination, were performed. Data analysis included eyes ipsilateral to ICAS (EIS) and eyes contralateral to ICAS (ECS)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28491466/changes-in-retinal-function-and-cellular-remodeling-following-experimental-retinal-detachment-in-a-rabbit-model
#16
Tilda Barliya, Ron Ofri, Shai Sandalon, Dov Weinberger, Tami Livnat
Purpose. To explore functional electroretinographic (ERG) changes and associated cellular remodeling following experimental retinal detachment in a rabbit model. Methods. Retinal detachment was created in ten rabbits by injecting 0.1 ml balanced salt solution under the retina. Fundus imaging was performed 0, 3, 7, 14, and 21 days postoperatively. ERGs were recorded pre- and 7 and 21 days postoperatively. Eyes were harvested on day 21 and evaluated immunohistochemically (IHC) for remodeling of second- and third-order neurons...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28484649/short-term-clinical-results-of-ab-interno-trabeculotomy-using-the-trabectome-with-or-without-cataract-surgery-for-open-angle-glaucoma-patients-of-high-intraocular-pressure
#17
Handan Akil, Vikas Chopra, Alex S Huang, Ramya Swamy, Brian A Francis
Purpose. To assess the safety and efficacy of Trabectome procedure in patients with preoperative intraocular pressure (IOP) of 30 mmHg or higher. Methods. All patients who had underwent Trabectome stand-alone or Trabectome combined with phacoemulsification were included. Survival analysis was performed by using Kaplan-Meier, and success was defined as IOP ≤ 21 mmHg, 20% or more IOP reduction from baseline for any two consecutive visits after 3 months, and no secondary glaucoma surgery. Results. A total of 49 cases were included with an average age of 66 (range: 13-91)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28484648/the-effectiveness-of-pre-and-postoperative-infliximab-in-controlling-beh%C3%A3-et-s-disease-posterior-uveitis-in-patients-undergoing-vitrectomy-a-preliminary-study
#18
Hossam El Din Mohamed Khalil, Heba A El Gendy, Hala Ahmed Raafat, Hazem Effat Haroun, Tamer Atef Gheita, Hossam Mahmoud Bakir
Purpose. To evaluate the short-term effectiveness of infliximab in controlling ocular manifestations in Behçet's Disease (BD) patients candidate for pars plana vitrectomy, if given in a regimen before and after the planned procedure. Patients and Methods. 30 eyes of 27 adult male BD patients with a mean age of 35.56 yrs presented with refractory posterior uveitis not responding to immunosuppressive drugs and candidate for vitrectomy were included. Infliximab was given in a dose of 5 mg/kg intravenous infusion once every two weeks for 3 treatment sessions before the intended vitrectomy followed by 3 treatment sessions at two-week intervals, after vitrectomy...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28484647/optimal-keratoplasty-for-the-correction-of-presbyopia-and-hypermetropia
#19
Daniele Veritti, Valentina Sarao, Paolo Lanzetta
Purpose. To evaluate prospectively the safety and efficacy of optimal keratoplasty for the correction of hyperopia and presbyopia. Methods. Consecutive patients undergoing bilateral optimal keratoplasty for refractive presbyopic and hypermetropic corrections were enrolled. Each patient received a complete ophthalmologic examination at baseline, 1 hour, 1 day, 1 week, 1 month, 3 months, and 6 months after treatment. Results. The study included 40 consecutive eyes of 20 patients. All patients reached the 6-month follow-up...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28484646/patient-preferences-with-regard-to-laser-versus-intravitreal-injections-in-the-treatment-of-diabetic-macular-edema
#20
Lauren Mason, Jason N Crosson, John O Mason, Gerald McGwin
Purpose. To identify treatment preferences of patients with diabetic macular edema (DME) having undergone laser and intravitreal injections. Methods. Patients with DME who received lasers and injections were surveyed, measuring preferences toward specific treatments. 66/210 diabetic patients met the criteria for our survey assessing preference for lasers and/or injections, incorporating demographics and treatment preference questions. Outcome measures included treatment preference (laser or injections), how often patients are willing to be treated, and how much vision they will sacrifice to avoid being treated every month...
2017: Journal of Ophthalmology
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