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Journal of Ophthalmology

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https://www.readbyqxmd.com/read/29785304/application-of-25-mhz-b-scan-ultrasonography-to-determine-the-integrity-of-the-posterior-capsule-in-posterior-polar-cataract
#1
Yawen Guo, Chengzhe Lu, Bin Wu, Jianmin Gao, Jun Li, Xiaoyong Yuan, Xin Tang
Purpose: To report the application of 25 MHz B-scan ultrasonography (MHzB) to determine the integrity of the posterior capsule (PC) in posterior polar cataract (PPC). Methods: Patients with whom PPC was clinically diagnosed using slit lamp microscopy who underwent 25 MHzB before phacoemulsification were retrospectively reviewed. The status of the PC was determined by 25 MHzB before phacoemulsification and confirmed during cataract surgery. Results: In total, 21 eyes in 14 clinically diagnosed PPC patients were enrolled in this study...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785303/ocular-manifestations-of-biopsy-proven-pulmonary-sarcoidosis-in-korea
#2
Seung Yong Choi, Jae Hoon Lee, Jae-Yon Won, Jeong Ah Shin, Young-Hoon Park
Purpose: To investigate the clinical features and ocular manifestations of biopsy-proven pulmonary sarcoidosis in Korea. Methods: 55 patients diagnosed with pulmonary sarcoidosis by bronchoscopic or excisional biopsy were included. By retrospective clinical chart review, we investigated features of uveitis, ocular and systemic treatments, visual acuity, angiotensin-converting enzyme level, chest radiography, and pulmonary function tests. Clinical features were analyzed by presence of uveitis, site of biopsy, and first manifested sign of sarcoidosis...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785302/comparisons-of-visual-and-surgical-outcomes-after-reuse-or-replacement-of-dislocated-in-the-bag-intraocular-lens
#3
Takayuki Baba, Tomohiro Nizawa, Toshiyuki Oshitari, Shuichi Yamamoto
Purpose: To compare the visual and surgical outcomes after a reuse or a replacement of a dislocated in-the-bag intraocular lens (IOL). Methods: This was a retrospective, nonrandomized case series at a single ophthalmological institution. Cases with an in-the-bag dislocation of an IOL were treated by pars plana vitrectomy and the reuse or the replacement of the IOL. The lens was held by intrascleral fixation of the haptics of the IOL under both conditions. The same dislocated IOL was reused in 6 eyes (group A) or it was replaced with another IOL in the other 9 eyes (group B)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785301/impact-of-baseline-central-retinal-thickness-on-outcomes-in-the-vivid-dme-and-vista-dme-studies
#4
Edoardo Midena, Mark Gillies, Todd A Katz, Carola Metzig, Chengxing Lu, Yuichiro Ogura
Purpose: To report the impact of baseline central retinal thickness (CRT) on outcomes in patients with diabetic macular edema (DME) in VIVID-DME and VISTA-DME. Methods: Post hoc analyses of two randomized controlled trials in which 862 DME patients were randomized 1 : 1 : 1 to treatment with intravitreal aflibercept 2.0 mg every 4 weeks (2q4), intravitreal aflibercept 2.0 mg every 8 weeks after five initial monthly doses (2q8), or macular laser photocoagulation at baseline and as needed...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785300/corneal-stability-following-hyperopic-lasik-with-advanced-laser-ablation-profiles-analyzed-by-a-light-propagation-study
#5
Almutez M Gharaibeh, Asier Villanueva, David Mas, Julian Espinosa, Jorge L Alió
Purpose: To assess anterior corneal surface stability 12 months following hyperopic LASIK correction with a light propagation algorithm. Setting: Vissum Instituto Oftalmológico de Alicante, Universidad Miguel Hernández, Alicante, Spain. Methods: This retrospective consecutive observational study includes 37 eyes of 37 patients treated with 6th-generation excimer laser platform (Schwind Amaris). Hyperopic LASIK was performed in all of them by the same surgeon (JLA) and completed 12-month follow-up...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29780638/molecular-genetics-of-pigment-dispersion-syndrome-and-pigmentary-glaucoma-new-insights-into-mechanisms
#6
REVIEW
Adrian A Lahola-Chomiak, Michael A Walter
We explore the ideas and advances surrounding the genetic basis of pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG). As PG is the leading cause of nontraumatic blindness in young adults and current tailored interventions have proven ineffective, a better understanding of the underlying causes of PDS, PG, and their relationship is essential. Despite PDS being a subclinical disease, a large proportion of patients progress to PG with associated vision loss. Decades of research have supported a genetic component both for PDS and conversion to PG...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29765780/outcomes-and-complications-of-scleral-fixated-intraocular-lens-combined-with-ahmed-tube-surgery
#7
Nikhel Sachdev, Maria Cecilia Aquino, Seng Chee Loon, Yiong Huak Chan, Paul Chew, Victor Koh
Background: To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes. Design: This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at Singapore's National University Hospital. Participants underwent an Ahmed tube surgery, together with transscleral suture-fixated posterior chamber intraocular lens...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29765779/effect-of-timing-of-initial-cataract-surgery-compliance-to-amblyopia-therapy-on-outcomes-of-secondary-intraocular-lens-implantation-in-chinese-children-a-retrospective-case-series
#8
Liuyang Li, Yan Wang, Caihong Xue
Purpose: As a secondary analysis, we reassess the association of initial congenital cataract surgery times, compliance to amblyopia therapy, and visual outcomes for a long-term follow-up in a secondary IOL implantation. Methods: Retrospective review of records of all infants with congenital cataracts who underwent secondary IOL implantation in the Eye and ENT Hospital of Fudan University from January 1, 2001, to December 31, 2007, and the minimum follow-up period was 5 years...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750124/a-small-disc-area-is-a-risk-factor-for-visual-field-loss-progression-in-primary-open-angle-glaucoma-the-glaucoma-stereo-analysis-study
#9
Yasushi Kitaoka, Masaki Tanito, Yu Yokoyama, Koji Nitta, Maki Katai, Kazuko Omodaka, Toru Nakazawa
Purpose: The Glaucoma Stereo Analysis Study, a cross-sectional multicenter collaborative study, used a stereo fundus camera (nonmyd WX) to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients. We compared the associations of each parameter between the visual field loss progression group and no-progression group. Methods: The study included 187 eyes of 187 patients with primary open-angle glaucoma or normal-tension glaucoma. We divided the mean deviation (MD) slope values of all patients into the progression group (<-0...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750123/visual-subfield-progression-in-glaucoma-subtypes
#10
Wei-Wen Su, Shian-Sen Hsieh, Shih-Tsung Cheng, Cheng-Wen Su, Wei-Chi Wu, Henry Shen-Lih Chen
Purpose: To investigate visual field progression pattern and factors associated with progression in patients with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and chronic angle-closure glaucoma (CACG). Methods: The raw data of the 30-2 Humphrey Field Analyzer from glaucoma patients with definite visual field progression were processed with pointwise linear regression (PLR) analysis. The rate of change of retinal threshold sensitivity in the ten glaucoma hemifield test (GHT) zones, the upper and the lower hemifields, and the whole field was evaluated and was correlated with patients' basic demographic data...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750122/analysis-of-visual-field-defects-obtained-with-semiautomated-kinetic-perimetry-in-patients-with-leber-hereditary-optic-neuropathy
#11
Katarzyna Nowomiejska, Agnieszka Kiszka, Edyta Koman-Wierdak, Katarzyna Tonska, Ryszard Maciejewski, Anselm G Jünemann, Robert Rejdak
Purpose: To analyse visual field (VF) defects obtained using semiautomated kinetic perimetry (SKP) in patients suffering from Leber hereditary optic neuropathy (LHON). Methods: Twenty-two eyes of eleven consecutive LHON male patients with confirmed mitochondrial 11778G>A DNA mutation were prospectively examined with the V4e stimulus of SKP in both eyes. The mean time after the onset of LHON was one year. The area of obtained isopters was measured in square degrees (deg2 )...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750121/-in-vivo-confocal-microscopic-observations-of-vortex-keratopathy-in-patients-with-amiodarone-induced-keratopathy-and-fabry-disease
#12
Yasuhito Ikegawa, Atsushi Shiraishi, Yasuhito Hayashi, Akiyoshi Ogimoto, Yuichi Ohashi
Purpose: To compare the morphology of two types of vortex keratopathy: amiodarone-induced keratopathy and the Fabry disease-associated keratopathy. Patients and Methods: Eight patients who were receiving oral amiodarone therapy and 3 patients with Fabry disease, a mother and her 2 daughters, were examined by slit-lamp biomicroscopy and in vivo confocal microscopy (IVCM) regularly. Results: Amiodarone-induced keratopathy developed in 7 of the 8 patients, and it was detected as early as 7 days by IVCM and 14 days by slit-lamp biomicroscopy...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750120/changing-trends-in-eye-related-complaints-presenting-to-the-emergency-department-in-beirut-lebanon-over-15-years
#13
Haytham I Salti, Carl-Joe Mehanna, Bachir Abiad, Nicola Ghazi, Samih Raad, Anita Barikian, Randa Haddad, Adnan Ashkar, Elie Harmouche, Elie Zaghrini, Afif Mufarrij
Objective: To report the 15-year trend in ophthalmic presentations to the emergency department (ED) at the only medical center in Lebanon that provides 24-hour ophthalmologic care. Methods: Retrospective review of 1967 patients presenting to the ED with eye-related complaints between September 1997 and August 1998 and between September 2012 and August 2013. Diagnoses were classified into 4 categories according to the International Society of Ocular Trauma and include penetrating eye injuries, nonpenetrating eye trauma, nontraumatic ophthalmic emergencies, and nontraumatic, nonurgent ophthalmic conditions...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29736282/biomaterial-influence-on-intraocular-lens-performance-an-overview
#14
REVIEW
Cari Pérez-Vives
There is strong evidence that the IOL material is the factor having the greatest impact on posterior capsule opacification (PCO), anterior capsule opacification (ACO) development, and glistening formation after cataract surgery, even though there are other IOL features-such as haptic material and design and edge and optic design-that also have some influence. We reviewed the published literature describing the adverse events that are mainly related to the intraocular lens (IOL) material, such as PCO, ACO, and the subsequent capsule contraction, as well as glistening formation...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29736281/association-of-optic-neuritis-with-cyp4f2-gene-single-nucleotide-polymorphism-and-il-17a-concentration
#15
Mantas Banevicius, Alvita Vilkeviciute, Brigita Glebauskiene, Loresa Kriauciuniene, Rasa Liutkeviciene
Background: The aetiology and pathophysiology of optic neuritis (ON) is not absolutely clear but genetic and inflammatory factors may be also involved in its development. The aim of the present study was to determine the influence of single nucleotide polymorphism (SNP) of CYP4F2 (rs1558139) and serum levels of IL-17A on ON development. Materials and Methods: Forty patients with ON and 164 control subjects were evaluated. Patients were divided by gender, also ON patients were divided into two subgroups: ON with and without multiple sclerosis (MS)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29736280/the-effect-of-perioperative-fluid-management-on-intraocular-pressure-during-gynecologic-laparoscopic-pelvic-surgery
#16
Izakson Alexander, Sindawi Ahmad, Ben Shachar Inbar, Pikkel Joseph
Purpose: Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body positions throughout the procedure, and to compare fluctuations of IOP during the perioperative period according to two fluid management protocols. Methods: Thirty women scheduled to undergo elective gynecologic laparoscopic pelvic surgery were randomly allocated to receive a liberal or restrictive fluid management protocol...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29736279/phenotypic-progression-of-stargardt-disease-in-a-large-consanguineous-tunisian-family-harboring-new-abca4-mutations
#17
Yousra Falfoul, Imen Habibi, Ahmed Turki, Ahmed Chebil, Asma Hassairi, Daniel F Schorderet, Leila El Matri
To assess the progression of Stargardt (STGD) disease over nine years in two branches of a large consanguineous Tunisian family. Initially, different phenotypes were observed with clinical intra- and interfamilial variations. At presentation, four different retinal phenotypes were observed. In phenotype 1, bull's eye maculopathy and slight alteration of photopic responses in full-field electroretinography were observed in the youngest child. In phenotype 2, macular atrophy and yellow white were observed in two brothers...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29725542/macular-integrity-assessment-and-fixation-analysis-in-chronic-central-serous-chorioretinopathy
#18
Joanna Dolar-Szczasny, Anna Święch-Zubilewicz, Jerzy Mackiewicz
Purpose: To investigate retinal sensitivity characteristics associated with morphologic changes in the eyes exhibiting chronic central serous chorioretinopathy (CSC), using macular integrity assessment (MAIA) microperimetry. Methods: A retrospective, cross-sectional, observational study was constructed. The eyes of patients classified as chronic CSC, according to the onset of subjective symptoms with serous retinal detachment, as confirmed by optical coherence tomography examination, were included in the study...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29713526/long-term-functional-and-anatomical-outcome-after-descemet-stripping-automated-endothelial-keratoplasty-a-prospective-single-center-study
#19
Jeroen van Rooij, Angela Engel, Lies Remeijer, Hugo van Cleijnenbreugel, René Wubbels
Purpose: To investigate the long-term anatomical and functional outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: Prospective follow-up of 114 eyes (95 subjects) after DSAEK for endothelial dysfunction. Measurements included best spectacle-corrected visual acuity (BSCVA), straylight, endothelial cell density (ECD), and graft thickness. Results: The mean follow-up time was 5.1 ± 1.5 years. Four grafts ultimately failed (after 5 to 7 years)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29713525/efficacy-of-osthole-in-management-of-hypoperfused-retina
#20
Ran Du, Zhao-Yang Meng, Jia-Lin Wang, Yan-Ling Wang
Purpose: To determine the effect of osthole on the retina in a chronic cerebral hypoperfusion (CCH) rat model and to investigate its therapeutic activity. Methods: Seventy-two rats were randomly allocated into 6 groups. CCH was induced by permanent bilateral common carotid artery occlusion (BCCAO) in five groups. Sham surgery was performed without occlusion of the artery in the sixth group (control group). Animals were administered with saline (model group), osthole (osthole-IG group), aspirin (aspirin group), or ginaton (ginaton group); the osthole-PI group was performed with peribulbar injection of osthole...
2018: Journal of Ophthalmology
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