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Journal of Ophthalmology

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https://www.readbyqxmd.com/read/27895937/medical-management-of-glaucoma-in-the-21st-century-from-a-canadian-perspective
#1
REVIEW
Paul Harasymowycz, Catherine Birt, Patrick Gooi, Lisa Heckler, Cindy Hutnik, Delan Jinapriya, Lesya Shuba, David Yan, Radmila Day
Glaucoma is a medical term describing a group of progressive optic neuropathies characterized by degeneration of retinal ganglion cells and retinal nerve fibre layer and resulting in changes in the optic nerve head. Glaucoma is a leading cause of irreversible vision loss worldwide. With the aging population it is expected that the prevalence of glaucoma will continue to increase. Despite recent advances in imaging and visual field testing techniques that allow establishment of earlier diagnosis and treatment initiation, significant numbers of glaucoma patients are undiagnosed and present late in the course of their disease...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27891250/diabetic-macular-ischemia-diagnosis-comparison-between-optical-coherence-tomography-angiography-and-fluorescein-angiography
#2
Jose Mauricio Botto de Barros Garcia, Talita Toledo Lima, Ricardo Noguera Louzada, Alessandra Thome Rassi, David Leonardo Cruvinel Isaac, Marcos Avila
Purpose. To compare fluorescein angiography (FA) and optical coherence tomography angiography (OCTA) images of foveal avascular zone (FAZ) in patients with diabetic retinopathy (DR) with and without diabetic macular ischemia (DMI). Methods. The Wilcoxon signed-rank test was used to compare area measurements and p values of <0.05 were considered statistically significant. FA and OCTA images were independently graded by 2 observers that reached agreement regarding quantitative DMI according established protocols...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27885338/effects-of-intravitreal-ranibizumab-injection-on-chinese-patients-with-wet-age-related-macular-degeneration-5-year-follow-up-results
#3
Yingyi Lu, Jianfeng Huang, Jing Zhao, Xiaobing Yu, Li Long, Hong Dai
Purpose. To observe the effect of intravitreal ranibizumab injection on wet age-related macular degeneration (wAMD) over 5 years in Chinese patients. Methods. Thirty-seven patients who were diagnosed with wAMD in our hospital from June 2007 to June 2014 were retrospectively reviewed. The PRN regimen and the treatment and extend regimen were applied. Best corrected visual acuity (BCVA), number of ranibizumab injections, and changes in the choroidal neovascularization (CNV) lesion over 5 years were analyzed. Results...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27885337/the-nonmydriatic-fundus-camera-in-diabetic-retinopathy-screening-a-cost-effective-study-with-evaluation-for-future-large-scale-application
#4
Giuseppe Scarpa, Francesca Urban, Stela Vujosevic, Michele Tessarin, Giovanni Gallo, Annalisa Visentin, Emanuela Foglia, Lucrezia Ferrario, Edoardo Midena
Aims. The study aimed to present the experience of a screening programme for early detection of diabetic retinopathy (DR) using a nonmydriatic fundus camera, evaluating the feasibility in terms of validity, resources absorption, and future advantages of a potential application, in an Italian local health authority. Methods. Diabetic patients living in the town of Ponzano, Veneto Region (Northern Italy), were invited to be enrolled in the screening programme. The "no prevention strategy" with the inclusion of the estimation of blindness related costs was compared with screening costs in order to evaluate a future extensive and feasible implementation of the procedure, through a budget impact approach...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27882245/ocular-biocompatibility-of-poly-n-isopropylacrylamide-pnipam
#5
Luiz H Lima, Yael Morales, Thiago Cabral
Purpose. To study the safety of intravitreal injections of poly-N-isopropylacrylamide (pNIPAM) tissue adhesive in rabbit eyes. Methods. Twelve study rabbits received an intravitreal injection of 0.1 mL 50% pNIPAM in the right eye. Follow-up examinations included color fundus photography, fundus fluorescein angiography (FA), optical coherence tomography (OCT), and electroretinography (ERG). Subsequent to the last follow-up assessment, the rabbits were sacrificed and histopathological study on the scleral incision sites was performed...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27882244/evaluation-of-peripapillary-nerve-fiber-layer-after-dexamethasone-implantation-ozurdex-in-branch-retinal-vein-occlusions
#6
Muhammed Nurullah Bulut, Yusuf Özertürk, Ümit Çallı, Güzide Akçay, Ulviye Kıvrak, Kezban Bulut
Purpose. To evaluate the peripapillary retinal nerve fiber layer (RNFL) thicknesses of patients treated with intravitreal Ozurdex implant due to branch retinal vein occlusion (BRVO) related macular edema (ME). Methods. Thirty-three eyes of 33 patients treated with Ozurdex implant due to ME associated with BRVO were included in the study. Ophthalmic examinations including determination of best corrected visual acuity (BCVA), measurement of intraocular pressure (IOP), and central macular thickness (CMT) and peripapillary RNFL assessment with optical coherence tomography (OCT) were performed before the injection of Ozurdex implant and during the 6-month follow-up period after the injection...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27882243/glaukos-istent-inject%C3%A2-trabecular-micro-bypass-implantation-associated-with-cataract-surgery-in-patients-with-coexisting-cataract-and-open-angle-glaucoma-or-ocular-hypertension-a-long-term-study
#7
Pedro Arriola-Villalobos, Jose Maria Martinez-de-la-Casa, David Diaz-Valle, Laura Morales-Fernandez, Cristina Fernandez-Perez, Julian Garcia-Feijoo
Purpose. To evaluate the long-term efficacy and safety of the iStent inject device (Glaukos Corporation, Laguna Hills, CA) combined with phacoemulsification in patients with coexistent cataract and open-angle glaucoma or ocular hypertension (OHT). Methods. A prospective, uncontrolled, nonrandomized, interventional case series study was conducted in patients with both mild or moderate open-angle glaucoma or OHT and cataract. Patients underwent cataract surgery along with the implant of two iStent inject devices...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27872755/changes-in-anterior-segment-morphology-of-iris-bombe-before-and-after-laser-peripheral-iridotomy-in-patients-with-uveitic-secondary-glaucoma
#8
Wakako Ikegawa, Takashi Suzuki, Koji Namiguchi, Shiro Mizoue, Atsushi Shiraishi, Yuichi Ohashi
Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27872754/evaluation-of-contrast-sensitivity-chromatic-vision-and-reading-ability-in-patients-with-primary-open-angle-glaucoma
#9
Maria P Bambo, Blanca Ferrandez, Noemi Güerri, Isabel Fuertes, Beatriz Cameo, Vicente Polo, Jose M Larrosa, Elena Garcia-Martin
Purpose. To compare contrast sensitivity, acquired color vision deficiency, and reading ability in patients with glaucoma at different stages of the disease and to establish correlations between visual field parameters and visual function scores. Methods. This prospective cross-sectional study included 121 glaucoma patients. Subjects with a diagnosis of chronic open angle glaucoma were recruited and classified according to Hodapp-Parrish-Anderson criteria. Patients with severe visual field defects were excluded because they were older, which could bias the interpretation of visual function tests...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27867660/corneal-aberrations-contrast-sensitivity-and-light-distortion-in-orthokeratology-patients-1-year-results
#10
Elena Santolaria-Sanz, Alejandro Cerviño, José M González-Méijome
Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. Results. LD showed an increase after the first night (p < 0...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27867659/ganglion-cell-inner-plexiform-layer-peripapillary-retinal-nerve-fiber-layer-and-macular-thickness-in-eyes-with-myopic-%C3%AE-zone-parapapillary-atrophy
#11
Jin-Woo Kwon, Jin A Choi, Jung-Sub Kim, Tae Yoon La
Purpose. To assess the correlations of myopic β-zone parapapillary atrophy (β-PPA) with the optic nerve head (ONH) and retina. Methods. We selected 27 myopic patients who showed prominent β-PPA in one eye and no β-PPA in the other eye. We studied their macula, macular ganglion cell-inner plexiform layer (mGCIPL), peripapillary retinal nerve fiber layer (pRNFL) thickness, and ONH parameters using optical coherence tomography. Results. The average of five out of six sectors and minimum values of mGCIPL thicknesses in eyes with prominent β-PPA discs were significantly less than those of the control eyes...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27867658/man-versus-machine-software-training-for-surgeons-an-objective-evaluation-of-human-and-computer-based-training-tools-for-cataract-surgical-performance
#12
Nizar Din, Phillip Smith, Krisztina Emeriewen, Anant Sharma, Simon Jones, James Wawrzynski, Hongying Tang, Paul Sullivan, Silvestro Caputo, George M Saleh
This study aimed to address two queries: firstly, the relationship between two cataract surgical feedback tools for training, one human and one software based, and, secondly, evaluating microscope control during phacoemulsification using the software. Videos of surgeons with varying experience were enrolled and independently scored with the validated PhacoTrack motion capture software and the Objective Structured Assessment of Cataract Surgical Skill (OSACCS) human scoring tool. Microscope centration and path length travelled were also evaluated with the PhacoTrack software...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27867657/method-of-quantifying-size-of-retinal-hemorrhages-in-eyes-with-branch-retinal-vein-occlusion-using-14-square-grid-interrater-and-intrarater-reliability
#13
Yuko Takashima, Masahiko Sugimoto, Kumiko Kato, Maki Kozawa, Kengo Ikesugi, Hisashi Matsubara, Mineo Kondo
Purpose. To describe a method of quantifying the size of the retinal hemorrhages in branch retinal vein occlusion (BRVO) and to determine the interrater and intrarater reliabilities of these measurements. Methods. Thirty-five fundus photographs from 35 consecutive eyes with BRVO were studied. The fundus images were analyzed with Power-Point® software, and a grid of 14 squares was laid over the fundus image. Raters were asked to judge the percentage of each of the 14 squares that was covered by the hemorrhages, and the average of the 14 squares was taken to be the relative size of the retinal hemorrhage...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27847644/relationship-among-corneal-biomechanics-anterior-segment-parameters-and-geometric-corneal-parameters
#14
Sadık Görkem Çevik, Sertaç Argun Kıvanç, Berna Akova-Budak, Mediha Tok-Çevik
Purpose. To investigate the relationship between corneal biomechanical parameters, anterior segment parameters, and geometric corneal parameters in a healthy Caucasian group. Methods. This retrospective study included the healthy eyes with best corrected visual acuity of at least 20/40 of 122 Caucasian subjects. The anterior segment parameters and geometric corneal parameters such as corneal volume, central corneal thickness, horizontal and vertical corneal radii, anterior and posterior steep, and flat keratometric values were measured with a Scheimpflug camera...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27843644/effect-of-three-dimensional-printed-personalized-moisture-chamber-spectacles-on-the-periocular-humidity
#15
Chan Hee Moon, Jae Yong Kim, Myoung Joon Kim, Hungwon Tchah, Byeong Gak Lim, Jin Kwon Chung
Purpose. To assess the effect of three-dimensional (3D) printed personalized moisture chamber spectacles (PMCS) on the periocular humidity. Methods. Facial computed tomography (CT) scanning was conducted on 10 normal subjects. PMCS was designed based on volume rendered CT images and produced using a 3D printer. Periocular humidity of PMCS and commercially available uniformed moisture chamber spectacles (UMCS) were measured for 30 minutes via microhydrometer. Results. The mean ambient humidity was 15.76 ± 1...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27843643/changing-clinical-presentation-current-knowledge-attitude-practice-and-current-vision-related-quality-of-life-in-self-reported-type-2-diabetes-patients-with-retinopathy-in-eastern-india-the-lvpei-eye-and-diabetes-study
#16
Taraprasad Das, Batriti Wallang, Preeti Semwal, Soumyava Basu, Tapas R Padhi, Mohd Hasnat Ali
Purpose. To document the changing clinical presentation of diabetic retinopathy (DR) over a decade, the current knowledge-attitude-practice (KAP) of known type 2 diabetes mellitus (DM) patients, and the current vision related quality of life (VR-QOL) of patients with DR in a tertiary eye care center in Eastern India. Methods. Two hundred and forty patients with known type-2 DM were evaluated. The evaluation included status of DR (n = 240), KAP (n = 232), and VR-QOL (n = 75). International classification of DR was used in the study...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27840739/optical-coherence-tomography-as-a-biomarker-for-diagnosis-progression-and-prognosis-of-neurodegenerative-diseases
#17
REVIEW
Maria Satue, Javier Obis, Maria J Rodrigo, Sofia Otin, Maria I Fuertes, Elisa Vilades, Hector Gracia, Jose R Ara, Raquel Alarcia, Vicente Polo, Jose M Larrosa, Luis E Pablo, Elena Garcia-Martin
Neurodegenerative diseases present a current challenge for accurate diagnosis and for providing precise prognostic information. Developing imaging biomarkers for multiple sclerosis (MS), Parkinson disease (PD), and Alzheimer's disease (AD) will improve the clinical management of these patients and may be useful for monitoring treatment effectiveness. Recent research using optical coherence tomography (OCT) has demonstrated that parameters provided by this technology may be used as potential biomarkers for MS, PD, and AD...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27840738/an-experimental-study-on-botulinum-toxin-type-a-for-the-treatment-of-excessive-secretion-after-submandibular-gland-transplantation-in-rabbits
#18
Shang Xie, Hui Xu, Bo Lin, Kan Wang, Xiao-Feng Shan, Zhi-Gang Cai
Objectives. To investigate whether botulinum toxin type A (BTXA) could control excessive secretion after submandibular gland (SMG) transplantation in rabbits and its possible mechanisms. Methods. A new SMG transplantation model was established in rabbit. 30 successfully constructed models were randomly assigned to five groups including control group and four experimental groups. Secretion outputs were used to analyze the effect of BTXA injection on excessive secretion. Hematoxylin and eosin (HE) staining, transmission electron microscopy (TEM), Western blot, and immunofluorescence were performed to analyze its possible mechanisms...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830086/active-pedicle-epithelial-flap-transposition-combined-with-amniotic-membrane-transplantation-for-treatment-of-nonhealing-corneal-ulcers
#19
Ting Zhang, Yuexin Wang, Yanni Jia, Dongle Liu, Suxia Li, Weiyun Shi, Hua Gao
Introduction. The objective was to evaluate the efficacy of active pedicle epithelial flap transposition combined with amniotic membrane transplantation (AMT) in treating nonhealing corneal ulcers. Material and Methods. Eleven patients (11 eyes) with nonhealing corneal ulcer who underwent the combined surgery were included. Postoperatively, ulcer healing time was detected by corneal fluorescein staining. Visual acuity, intraocular pressure, surgical complications, and recurrence were recorded. Corneal status was inspected by the laser scanning confocal microscopy and anterior segment optical coherence tomography (AS-OCT)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830085/response-to-comment-on-choroidal-thickness-in-patients-with-mild-cognitive-impairment-and-alzheimer-s-type-dementia
#20
COMMENT
Mehmet Bulut, Aylin Yaman, Muhammet Kazim Erol, Fatma Kurtuluş, Devrim Toslak, Berna Doğan, Deniz Turgut Çoban, Ebru Kaya Başar
No abstract text is available yet for this article.
2016: Journal of Ophthalmology
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