journal
MENU ▼
Read by QxMD icon Read
search

Journal of Ophthalmology

journal
https://www.readbyqxmd.com/read/29147580/molecular-age-related-changes-in-the-anterior-segment-of-the-eye
#1
REVIEW
Luis Fernando Hernandez-Zimbron, Rosario Gulias-Cañizo, María F Golzarri, Blanca Elizabeth Martínez-Báez, Hugo Quiroz-Mercado, Roberto Gonzalez-Salinas
Purpose: To examine the current knowledge about the age-related processes in the anterior segment of the eye at a biological, clinical, and molecular level. Methods: We reviewed the available published literature that addresses the aging process of the anterior segment of the eye and its associated molecular and physiological events. We performed a search on PubMed, CINAHL, and Embase using the MeSH terms "eye," "anterior segment," and "age." We generated searches to account for synonyms of these keywords and MESH headings as follows: (1) "Eye" AND "ageing process" OR "anterior segment ageing" and (2) "Anterior segment" AND "ageing process" OR "anterior segment" AND "molecular changes" AND "age...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29138695/risk-factors-of-malignant-glaucoma-occurrence-after-glaucoma-surgery
#2
Karolina Krix-Jachym, Tomasz Żarnowski, Marek Rękas
Purpose: The aim of this study was twofold: first, to evaluate the predisposing factors for occurrence of malignant glaucoma and second, to compare frequency of malignant glaucoma depending on the type of primary glaucoma surgery. Methods: Retrospective analysis was performed in 1689 consecutive patients who underwent glaucoma surgery alone or combined with phacoemulsification. Data collected included the type of surgery, width of the filtration angle, presence or absence of malignant glaucoma in the postoperative period, and time from the primary surgery to malignant glaucoma occurrence...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29138694/impact-of-topically-administered-steroids-antibiotics-and-sodium-hyaluronate-on-bleb-related-infection-onset-the-japan-glaucoma-society-survey-of-bleb-related-infection-report-4
#3
Hideto Sagara, Tetsuya Yamamoto, Kimihiro Imaizumi, Tetsuju Sekiryu
Purpose: To investigate the impact of topically administered ophthalmic medications on the onset and severity of bleb-related infections. Methods: Data obtained from 104 eyes of 104 patients with bleb-related infections were analyzed. We assigned an infection stage to each eye (stage 1-4) and analyzed the onset severity. Results: Steroids and antibiotics were routinely administered to 13 (12.5%) and 42 (40.4%) eyes, respectively. The median stage of steroid-administered eyes was 3 versus 1 for eyes without steroid administration (P = 0...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29129998/changes-in-retinal-and-choroidal-vascular-blood-flow-after-oral-sildenafil-an-optical-coherence-tomography-angiography-study
#4
David Berrones, Guillermo Salcedo-Villanueva, Virgilio Morales-Cantón, Raul Velez-Montoya
Purpose: To describe changes in the retina and choroidal flow by optical coherence tomography angiography (OCT-A) after a single dose of oral sildenafil. Method: A case-control study. Patients in the study group received 50 mg of oral sildenafil. Patients in the control group received a sham pill. Retinal and choroidal images were obtained at baseline (before pill ingestion) and 1 hour after ingestion. Central macular and choroidal thickness, choroidal and outer retina flow, and the retinal and choroidal vascular density were compared using a Mann-Whitney U test...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29119022/bruch-s-membrane-opening-minimum-rim-width-measurement-with-sd-oct-a-method-to-correct-for-the-opening-size-of-bruch-s-membrane
#5
Robert Kromer, Martin Stephan Spitzer
A precise evaluation of the retinal nerve fiber layer thickness (RNFLT) is key for diagnosing and monitoring glaucoma. The Bruch's membrane opening minimum rim width (BMO-MRW) has been proposed as a reproducible assessment of the optic nerve. The BMO-MRW measures the minimum distance from the BMO to the internal limiting membrane. We propose an approach to correct the BMO-MRW using the BMO size for increased accuracy in interindividual comparisons in future studies. Eighty-one healthy patients received SPECTRALIS spectral domain optical coherence tomography measurements for the peripapillary RNFLT and BMO-MRW...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29119021/comparison-between-the-correlations-of-retinal-nerve-fiber-layer-thickness-measured-by-spectral-domain-optical-coherence-tomography-and-visual-field-defects-in-standard-automated-white-on-white-perimetry-versus-pulsar-perimetry
#6
Maged Alnawaiseh, Lisann Hömberg, Nicole Eter, Verena Prokosch
Purpose: To compare the structure-function relationships between retinal nerve fiber layer thickness (RNFLT) and visual field defects measured either by standard automated perimetry (SAP) or by Pulsar perimetry (PP). Materials and Methods: 263 eyes of 143 patients were prospectively included. Depending on the RNFLT, patients were assigned to the glaucoma group (group A: RNFL score 3-6) or the control group (group B: RNFL score 0-2). Structure-function relationships between RNFLT and mean sensitivity (MS) measured by SAP and PP were analyzed...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29109868/visual-quality-assessment-of-posterior-capsule-opacification-using-optical-quality-analysis-system-oqas
#7
Hui Zhang, Jing Wang
Objective: To evaluate intraocular scattering in eyes with posterior capsule opacification by means of an objective scatter index (OSI) obtained from double-pass images of optical quality assessment system (OQAS TM II) and to determine the indication for laser capsulotomy when patients report visual disturbances without decreased visual acuity. Methods: In this prospective, observational, and nonconsecutive case series study, a total of 32 eyes of 29 patients are diagnosed with posterior capsule opacification after age-associated cataract were analyzed...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29109867/clinical-profile-of-unilateral-proptosis-in-a-tertiary-care-centre
#8
Susan Dsouza, Pooja Kandula, Gurudutt Kamath, Manjunath Kamath
Proptosis, the forward protrusion of the eyeball, is a common manifestation of a wide variety of diseases inside the orbit and its spaces. Its diagnosis is usually a combined effort of the ophthalmologist, otolaryngologist, neurosurgeon, and radiologist. A clinical study of twenty-five cases with unilateral proptosis were studied in different age groups over a period of about 3 years under different headings like distribution, clinical features, radiological features, histopathological aspects, management, and outcomes of diseases...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29109866/correlation-between-choroidal-neovascularization-shown-by-oct-angiography-and-choroidal-thickness-in-patients-with-chronic-central-serous-chorioretinopathy
#9
Joanna Gołębiewska, Joanna Brydak-Godowska, Joanna Moneta-Wielgoś, Monika Turczyńska, Dariusz Kęcik, Wojciech Hautz
Purpose: To assess the occurrence of choroidal neovascularization (CNV) secondary to chronic central serous chorioretinopathy (CSCR) using optical coherence tomography angiography (OCTA) and correlate these findings with choroidal thickness (CT). Materials and Methods: This retrospective study included 25 consecutive patients (43 eyes), mean age 48.12 ± 7.8 years, diagnosed with persistent CSCR. All patients underwent a complete ophthalmic examination, fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography, and OCTA...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29109865/om-101-decreases-the-fibrotic-response-associated-with-proliferative-vitreoretinopathy
#10
Zeev Dvashi, Keren Ben-Yaakov, Tamir Weinberg, Yoel Greenwald, Ayala Pollack
Purpose: This study aimed to investigate the effect of OM-101 on the fibrotic response occurring in proliferative vitreoretinopathy (PVR) in an animal model. Methods: Antifibrotic effect of OM-101 was investigated in vivo. As control, eight weeks old c57black mice underwent intravitreal injection with Hepes (group A) or dispase (0.3 units), to induce retinal detachment (RD) and PVR. The dispase-injected mice were randomly divided into two groups B and C (N = 25 mice); in group C, the eyes were treated with intravitreal injection of OM-101 (3 μl), and group B with PBS, as a control...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29104804/new-objective-refraction-metric-based-on-sphere-fitting-to-the-wavefront
#11
Mateusz Jaskulski, Andreí Martínez-Finkelshtein, Norberto López-Gil
Purpose: To develop an objective refraction formula based on the ocular wavefront error (WFE) expressed in terms of Zernike coefficients and pupil radius, which would be an accurate predictor of subjective spherical equivalent (SE) for different pupil sizes. Methods: A sphere is fitted to the ocular wavefront at the center and at a variable distance, t. The optimal fitting distance, topt, is obtained empirically from a dataset of 308 eyes as a function of objective refraction pupil radius, r0, and used to define the formula of a new wavefront refraction metric (MTR)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29104803/the-impact-of-adherence-and-instillation-proficiency-of-topical-glaucoma-medications-on-intraocular-pressure
#12
Tesfay Mehari Atey, Workineh Shibeshi, Abeba T Giorgis, Solomon Weldegebreal Asgedom
Background: The possible sequel of poorly controlled intraocular pressure (IOP) includes treatment failure, unnecessary medication use, and economic burden on patients with glaucoma. Objective: To assess the impact of adherence and instillation technique on IOP control. Methods: A cross-sectional study was conducted on 359 glaucoma patients in Menelik II Hospital from June 1 to July 31, 2015. After conducting a Q-Q analysis, multiple binary logistic analyses, linear regression analyses, and two-tailed paired t-test were conducted to compare IOP in the baseline versus current measurements...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098085/the-protective-effects-of-%C3%AE-b-crystallin-on-ischemia-reperfusion-injury-in-the-rat-retina
#13
Huan Yan, Yanli Peng, Wei Huang, Liyan Gong, Li Li
To investigate whether αB-crystallin protects against acute retinal ischemic reperfusion injury (I/R) and elucidate the potential antioxidant mechanisms. Retinal I/R injury was made by elevating the intraocular pressure (IOP) 110 mmHg for 60 min, and αB-crystallin (1 × 10(-5) g/L) or vehicle solution was administered intravitreously immediately after I/R injury. The animal was sacrificed 24 h, 1 w, and 1 m after the I/R injury. The retina damage was detected by hematoxylin and eosin (HE) staining and electroretinography (ERG)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098084/influence-of-overnight-orthokeratology-on-corneal-surface-shape-and-optical-quality
#14
Yuan Sun, Lin Wang, Jing Gao, Mei Yang, Qi Zhao
Purpose: To investigate the changes of corneal surface shape and optical quality during orthokeratology. Methods: 49 eyes of 26 patients (10.63 ± 2.02 years old) who underwent overnight orthokeratology for myopia were prospectively examined. The corneal surface shape parameters, including surface regularity index (SRI) and surface asymmetry index (SAI), were attained with an OPD-III SCAN. The higher-order aberrations and higher-order Strehl ratios were calculated under a 3 mm pupil diameter before orthokeratology, 1 month, 3 months, and 6 months after orthokeratology...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098083/an-analysis-of-3-year-outcomes-following-canaloplasty-for-the-treatment-of-open-angle-glaucoma
#15
Mahmoud A Khaimi, Justin D Dvorak, Kai Ding
Purpose: To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. Setting: University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. Design: Nonrandomized single-center retrospective chart review. Methods: Adult open-angle glaucoma eyes underwent canaloplasty or combined cataract-canaloplasty surgery. A tensioning suture was placed into Schlemm's canal in all eyes...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098082/inherited-retinal-degeneration-genetics-disease-characterization-and-outcome-measures
#16
EDITORIAL
Naheed W Khan, Benedetto Falsini, Mineo Kondo, Anthony G Robson
No abstract text is available yet for this article.
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098081/reduced-expression-of-vamp8-in-lacrimal-gland-affected-by-chronic-graft-versus-host-disease
#17
Masaki Fukui, Yoko Ogawa, Shin Mukai, Mizuka Kamoi, Teru Asato, Yutaka Kawakami, Kazuo Tsubota
Purpose: To investigate whether the SNARE protein vesicle-associated membrane protein 8 (VAMP8) was implicated in the development of chronic ocular graft-versus-host disease (GVHD). Methods: Firstly, the chronic GVHD (cGVHD) and Sjögren's syndrome (SS)-impaired lacrimal gland (LG) tissue sections from humans for diagnostic purpose were evaluated for VAMP8 expression by histopathology and immunohistochemistry. Next, serial changes of tear secretion and VAMP8 expression at both protein and mRNA level of LG in an animal cGVHD model compared with the syngeneic control...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29093970/two-year-outcome-of-aflibercept-in-patients-with-pigment-epithelial-detachment-due-to-neovascular-age-related-macular-degeneration-namd-refractory-to-ranibizumab
#18
Thi Ha Chau Tran, Stéphane Dumas, Florence Coscas
Purpose: To evaluate the response of intravitreal aflibercept injection (IAI) in eyes with detachment of retinal pigment epithelium (DEP) secondary to nAMD refractory to monthly ranibizumab. Patients and Methods: This is a retrospective, multicenter study. All patients received 3 IAI then treated as needed every 4 weeks for 12 months. During the second year, the eyes were treated with a treat- and-extend regimen. Results: Forty-four eyes were included...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29085673/analysis-of-factors-associated-with-the-ocular-features-of-congenital-cataract-children-in-the-shanghai-pediatric-cataract-study
#19
Wenwen He, Ting Sun, Jin Yang, Guoyou Qin, Zhenyu Wu, Xiangjia Zhu, Yi Lu
PURPOSE: To investigate the ocular features of children with congenital cataract in a tertiary referral eye center in East China. METHODS: We retrospectively reviewed the clinical data of congenital cataract children who underwent cataract surgery between April 2009 and April 2014 at the Eye and ENT Hospital of Fudan University and identified factors associated with the axial length (AXL) and corneal curvature (K value). RESULTS: We included 493 children, 210 with unilateral and 283 with bilateral cataract...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29085672/steeper-iris-conicity-is-related-to-a-shallower-anterior-chamber-the-gutenberg-health-study
#20
Alexander K Schuster, Norbert Pfeiffer, Stefan Nickels, Andreas Schulz, Philipp S Wild, Maria Blettner, Karl Lackner, Manfred E Beutel, Thomas Münzel, Urs Vossmerbaeumer
PURPOSE: To report the distribution of iris conicity (steepness of the iris cone), investigate associated factors, and test whether pseudophakia allows the iris to sink back. METHODS: A population-based cross-sectional study was carried out. Ophthalmological examination including objective refraction, biometry, noncontact tonometry, and Scheimpflug imaging (Pentacam®, Oculus) was performed including automated measurement of iris conicity. 3708 phakic subjects, 144 subjects with bilateral and 39 subjects with unilateral pseudophakia were included...
2017: Journal of Ophthalmology
journal
journal
42867
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"