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Journal of Ophthalmology

Dandan Wang, Xiaoyu Yu, Zhangliang Li, Xixia Ding, Hengli Lian, Jianyang Mao, Yinying Zhao, Yun-E Zhao
Purpose: To evaluate the effect of anterior capsule polishing in patients with high myopia after cataract surgery. Setting: The Eye Hospital of Wenzhou Medical University, Zhejiang, China. Design: Prospective study. Methods: High myopic patients with a bilateral cataract who underwent phacoemulsification with 360° anterior capsular polishing in one eye and without polishing in the contralateral eye were recruited. The following parameters were recorded at 1, 3, and 6 months postoperatively, including the area and diameter of the anterior capsule opening (area and D), IOL tilt and decentration, refraction, and postoperative aqueous depth (PAD)...
2018: Journal of Ophthalmology
Zhi Chen, Jiaqi Zhou, Feng Xue, Xingtao Zhou, Xiaomei Qu
Purpose: To investigate the change in corneal toricity and associated refractive astigmatism after discontinuation of long-term orthokeratology (ortho-k) lens wear. Methods: This study investigated 136 subjects aged between 6 and 14 (9.1 ± 1.5) years old at the commencement of ortho-k treatment, who had been undergoing overnight ortho-k treatment for 24 to 72 (37.4 ± 11.9) months. Corneal refractive power and manifest refraction were measured and compared before ortho-k and 1 month after discontinuation of ortho-k lens wear...
2018: Journal of Ophthalmology
Vincenza Bonfiglio, Mario D Toro, Antonio Longo, Teresio Avitabile, Robert Rejdak, Katarzyna Nowomiejska, Tomasz Choragiewicz, Andrea Russo, Matteo Fallico, Agnieszka Kaminska, Elina Ortisi, Stefano Zenoni, Michele Reibaldi
Purpose: To evaluate the effects of a modification of the traditional 25-gauge pars plana vitrectomy technique in the treatment of uncomplicated macula-on rhegmatogenous retinal detachment (RRD) with intermediate retinal break(s) and marked vitreous traction in the phakic eye. Methods: Prospective, noncomparative, and interventional case series. All consecutive phakic eyes with primary uncomplicated macula-on RRD with intermediate retinal break(s) and marked vitreous traction, with at least 1 year of postoperative follow-up, were enrolled...
2018: Journal of Ophthalmology
Xiaolin Qi, Miaolin Wang, Xiaofeng Li, Yanni Jia, Suxia Li, Weiyun Shi, Hua Gao
Purpose: To observe clinical characteristics and treatment outcomes of new onset herpes simplex keratitis (HSK) after keratoplasty. Methods: Among 1,443 patients (1,443 eyes) who underwent keratoplasty (excluding cases of primary HSK) in Shandong Eye Hospital, 17 patients suffered postoperative HSK. The clinical manifestations, treatment regimens, and prognoses of the patients were evaluated. Results: The incidence of new onset HSK after keratoplasty was 1...
2018: Journal of Ophthalmology
Jianqing Li, Jiayi Xu, Yiyi Chen, Jiaju Zhang, Yihong Cao, Peirong Lu
Purpose: Intravitreal antivascular endothelial growth factor (anti-VEGF) therapy has been widely used for the treatment of neovascularization (NV) secondary to age-related macular degeneration (AMD). This study aimed to compare the efficacy among different subtypes of neovascular age-related macular degeneration (nAMD). Methods: PubMed, Embase, and the Cochrane Library were searched for eligible studies. We performed meta-analysis using Review Manager 5.3 and Stata/SE 12...
2018: Journal of Ophthalmology
Alper Ağca, İhsan Çakır, Beril Tülü Aygün, Dilek Yaşa, Yusuf Yıldırım, Burçin Kepez Yıldız, Ahmet Demirok
Purpose: To report long-term visual and refractive results of small-incision lenticule extraction (SMILE) in treatment of high myopia. Materials and Methods: Medical records of patients who underwent SMILE for surgical correction of myopia or myopic astigmatism were retrospectively reviewed. Only patients with a preoperative spherical equivalent of subjective manifest refraction (SE) ≥ 6 D and a postoperative follow-up of 5 years were included in the study. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and SE were analyzed preoperatively and at 1-, 3-, and 5-year postoperative periods...
2018: Journal of Ophthalmology
Yvan Jamilloux, Aude Taleb, Audrey De Parisot, Laurent Pérard, Carole Burillon, Christiane Broussolle, Laurent Kodjikian, Pascal Sève
Purpose: To describe patients with new onset sarcoid uveitis occurring after an ophthalmic procedure and compare them with patients with sarcoid uveitis without ocular procedure. Methods: Retrospective analysis of case records from patients with postophthalmic procedure sarcoid uveitis seen at our institution between April 2004 and October 2016. Patients with a previous history of uveitis were not included. Each patient was randomly matched with four controls from our incident cohort of new onset sarcoid uveitis without ophthalmic procedure...
2018: Journal of Ophthalmology
Chul Hee Lee, Min Woo Lee, Eun Young Choi, Suk Ho Byeon, Sung Soo Kim, Hyoung Jun Koh, Sung Chul Lee, Min Kim
Purpose: To compare changes in the retinal layer thickness and visual outcomes in patients undergoing epiretinal membrane (ERM) surgery with or without internal limiting membrane (ILM) peeling. Methods: Seventy-six eyes of 76 patients who underwent ERM surgery from January 2013 to March 2015 at the Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea, were analyzed. While ERM removal with ILM peeling was performed in ILM peeling (P) group ( n =39), ILM peeling was not performed in non-ILM peeling (NP) group ( n =37)...
2018: Journal of Ophthalmology
Wei-Ran Niu, Chun-Qiong Dong, Xi Zhang, Yi-Fan Feng, Fei Yuan
Purpose: To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods: In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowding value (defined as lens thickness (LT); central corneal thickness (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis was performed to identify risk factors for AAC...
2018: Journal of Ophthalmology
Chao Xue, Yaoqi Xiang, Min Shen, Di Wu, Yan Wang
Purpose: To investigate the anisotropic characteristics of the normal human corneal stroma using fresh corneal tissue. Methods: Sixty-four corneal specimens extracted from stromal lenticules were included in this study. The specimens were cut in the temporal-nasal (horizontal) or superior-inferior (vertical) direction. Strip specimens were subjected to uniaxial tensile testing. The tensile properties of the specimens were measured and compared in the two directions...
2018: Journal of Ophthalmology
Mingyu Shi, Liwei Ma, Jinsong Zhang, Qichang Yan
Background: The purpose of this observational case series study was to investigate the role of 25 MHz ultrasound biomicroscopy (UBM) in detecting subluxated lenses and compare it with 50 MHz UBM. Methods: 45 patients (49 eyes) with suspected subluxation of the lens and 20 normal volunteers (40 eyes) were included. Different cross-sectional images of the lens position were captured in axial and longitudinal scanning modes using 25 and 50 MHz UBM. The main outcome measurements included the linear distance between the lens equator and ciliary process, the difference value (D-value) between the same cross section of the above bilateral linear distance in the normal and the subluxated subjects, the diagnostic accuracy, and the testing times obtained with 25 and 50 MHz UBM...
2018: Journal of Ophthalmology
Hao-Chen Guo, Wan-Qing Jin, An-Peng Pan, Qin-Mei Wang, Jia Qu, A-Yong Yu
Purpose: To assess the changes and the diurnal variation of visual quality after orthokeratology in myopic children. Methods: Forty-four eyes of 22 subjects with a mean age of 10.55 ± 1.53 years (8 to 14 years) were enrolled in this prospective study. Their spherical equivalent ranged from -1.25 to -4.25 diopters (D) and astigmatism was less than 1.00 D. Parameters including corneal curvature, ocular objective scatter index (OSI), the modulation transfer function (MTF), root mean square of ocular and corneal wavefront aberrations, and contrast sensitivity function (CSF) were measured before and at two time points during the same day after 1 month of orthokeratology...
2018: Journal of Ophthalmology
Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego
Objectives: To evaluate efficacy and safety of an aflibercept treat-and-extend (TAE) regimen in patients with macular oedema (MO) secondary to central retinal vein occlusion (CRVO). Design Setting and Patients: Phase IV, prospective, open-label, single-arm trial in 11 Spanish hospitals. Treatment-naïve patients with <6 month diagnosis of MO secondary to CRVO and best-corrected visual acuity (BCVA) of 73-24 ETDRS letters were included between 23 January 2015 and 17 March 2016...
2018: Journal of Ophthalmology
Marcella Nebbioso, Marta Sacchetti, Guia Bianchi, Anna Maria Zicari, Marzia Duse, Paola Del Regno, Alessandro Lambiase
Background: Vernal keratoconjunctivitis (VKC) is a rare ocular surface inflammatory disease that affects mainly boys in the first decade of life. Clinical observations show that it generally regresses spontaneously with the onset of puberty, but therapeutic measures must be taken before then to control the course of the disease. Purpose: To evaluate the role of the lacrimal mucous component in VKC patients and compare tear ferning test (TFT) modifications, MUC5AC levels in tears, and density of conjunctival goblet cells to clinical characteristics before and after treatment with cyclosporine A (CY) in eye drops...
2018: Journal of Ophthalmology
Xiaoying Xu, Taixiang Liu, Haixiang Li
Objective: This study aims at investigating the effects and molecular mechanism of riboflavin-ultraviolet-A-induced cross-linking (corneal collagen cross-linking, CXL) on corneal neovascularization (CNV) in a rabbit alkali burn model. Methods: A total of 60 rabbits were injured with alkali burns to induce CNV in the right eye and were randomly divided into six groups: Group A-injury and no treatment; Groups B, C, and D-CXL treatment for 30 min, 15 min, and 45 min administered immediately after injury, respectively; and Groups E and F-CXL treatment for 30 min administered 1 day and 3 days after injury, respectively...
2018: Journal of Ophthalmology
Alessio Martucci, Nicola Toschi, Massimo Cesareo, Clarissa Giannini, Giulio Pocobelli, Francesco Garaci, Raffaele Mancino, Carlo Nucci
Introduction: To evaluate the sectorial thickness of single retinal layers and optic nerve using spectral domain optic coherence tomography (SD-OCT) and highlight the parameters with the best diagnostic accuracy in distinguishing between normal and glaucoma subjects at different stages of the disease. Material and Methods: For this cross-sectional study, 25 glaucomatous (49 eyes) and 18 age-matched healthy subjects (35 eyes) underwent a complete ophthalmologic examination including visual field testing...
2018: Journal of Ophthalmology
LakshmiPriya Rangaraju, Xuejuan Jiang, J Jason McAnany, Michael R Tan, Justin Wanek, Norman P Blair, Jennifer I Lim, Mahnaz Shahidi
Purpose: Diabetes is known to cause alterations in retinal microvasculature and tissue that progressively lead to visual impairment. Optical coherence tomography (OCT) is useful for assessment of total retinal thickening due to diabetic macular edema (DME). In the current study, we determined associations between visual acuity (VA) and retinal layer thickness, reflectance, and interface disruption derived from enface OCT images in subjects with and without DME. Materials and Methods: Best corrected VA was measured and high-density OCT volume scans were acquired in 149 diabetic subjects...
2018: Journal of Ophthalmology
Sherine S Wahba, Maged M Roshdy, Ramy R Fikry, Mona K Abdellatif, Abdulrahman M Abodarahim
Purpose: To investigate the correlation between decentration index (index of height decentration, IHD) automatically calculated by the Pentacam HR software and the manually calculated inferior minus superior (I-S) value. Setting: Al Watany Eye Hospital, Cairo, Egypt. Methods: In a retrospective study, history taking, clinical examination, and rotating Scheimpflug camera scanning (by Oculyzer II equivalent to Pentacam HR) were done to 128 eyes: 82 normal, 24 forme fruste keratoconus FFKC (apparently normal cornea with evident keratoconus in the fellow eye), and 22 keratoconus (KC)...
2018: Journal of Ophthalmology
Chieh-Hung Yen, Shu-Ya Wu, Yi-Lin Liao
Purpose: To report six cases of Klebsiella pneumoniae orbital cellulitis without preceding endophthalmitis. Method: Retrospective chart review. Results: We reported four females and two males admitted to our hospital for Klebsiella pneumoniae orbital cellulitis proven by computed tomographies and bacterial cultures from May 1995 to March 2017. Proptosis, conjunctival congestion, and chemosis and limitation of ocular motility were present in all six patients...
2018: Journal of Ophthalmology
Birgit Weingessel, Kata Miháltz, Andreas Gleiss, Florian Sulzbacher, Christopher Schütze, Pia V Vécsei-Marlovits
Purpose: Long-term follow-up of patients with diabetic macular edema (DME) treated with intravitreal antivascular endothelial growth factor (anti-VEGF) combined focal laser and identification of prognostic morphological characteristics. Methods: Prospective clinical trial (50 treatment-naive eyes) with DME randomized 1 : 1 receiving intravitreal ranibizumab (0.5 mg/0.05 ml) and prompt grid laser compared with ranibizumab and deferred laser. Morphological characteristics potentially relevant for prognosis were assessed at baseline, month 6, month 9, and years 1, 2, 3, 4, and 5 of follow-up...
2018: Journal of Ophthalmology
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