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Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28815090/effects-of-the-rho-kinase-inhibitor-y-27632-on-extraocular-muscle-surgery-in-rabbits
#1
Ji-Sun Moon, Hyun Kyung Kim, Sun Young Shin
PURPOSE: To evaluate the effect of the Rho-kinase inhibitor Y-27632 on postoperative inflammation and adhesion following extraocular muscle surgery in rabbits. METHODS: The superior rectus muscle reinsertion was performed on both eyes of 8 New Zealand white rabbits. After reinsertion, the rabbits received subconjunctival injections of the Rho-kinase inhibitor and saline on each eye. To assess acute and late inflammatory changes, Ki-67, CD11β+, and F4/80 were evaluated and the sites of muscle reattachment were evaluated for a postoperative adhesion score and histopathologically for collagen formation...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28815089/risk-assessment-for-corneal-ectasia-following-photorefractive-keratectomy
#2
Nir Sorkin, Igor Kaiserman, Yuval Domniz, Tzahi Sela, Gur Munzer, David Varssano
PURPOSE: To analyze the risk factors associated with a series of ectasia cases following photorefractive keratectomy (PRK) and all published cases. METHODS: In a retrospective study on post-PRK ectasia patients, 9 eyes of 7 patients were included, in addition to 20 eyes of 13 patients from the literature. Risk of post-PRK ectasia was calculated using the ectasia risk score system (ERSS) for laser in situ keratomileusis (LASIK) patients. The percent tissue altered (PTA) was also evaluated...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28815088/use-of-anti-vegf-agents-in-glaucoma-surgery
#3
REVIEW
Mark Slabaugh, Sarwat Salim
A number of antivascular endothelial growth factor agents are currently available to treat various ocular conditions. These agents have similar, but distinct, biologic qualities and have been explored in the management of neovascular glaucoma and in glaucoma surgery. Several different delivery methods are described, and because these medications are routinely given as intraocular injections, some benefits over traditional antifibrotic medications when used in glaucoma surgery are noted. These agents effectively induce regression of anterior segment neovascularization and facilitate initial surgical management of neovascular glaucoma, but the long-term outcome of this condition remains dependent on definitive management of the underlying process...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28815087/ocular-and-systemic-risk-factors-of-different-morphologies-of-scotoma-in-patients-with-normal-tension-glaucoma
#4
Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Urszula Łukasik, Tomasz Żarnowski
THE AIM: The aim of this study was to assess general and ocular profiles of patients with single-localisation changes in visual field. MATERIAL AND METHODS: The study group consisted of 215 Caucasian patients with normal-tension glaucoma with scotoma on single localisation or with preperimetric glaucoma. During regular follow-up visits, ophthalmic examination was carried out and medical history was recorded. The results of the visual field were allocated as paracentral scotomas, arcuate scotomas, peripheral defects, or hemispheric defects...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811936/real-life-management-of-patients-with-retinal-vein-occlusion-using-i-macula-web-platform
#5
Massimo Nicolò, Monica Bonetto, Raffaella Rosa, Donatella Musetti, Maria Musolino, Carlo Enrico Traverso, Mauro Giacomini
AIM: Real-life evaluation in the management of patients affected by macular edema secondary to retinal vein occlusion. MATERIAL AND METHODS: A retrospective, observational study using the I-Macula Web platform. RESULTS: Thirty-five patients (37 eyes; 15 females and 20 male) affected by RVO were analysed. At 12 months, there was a statistically significant improvement of best-corrected visual acuity (p = 0.0235) and central macular thickness (p < 0...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811935/pars-plana-vitrectomy-with-internal-limiting-membrane-peeling-in-traumatic-macular-hole-14-perfluoropropane-c3f8-versus-silicone-oil-tamponade
#6
Ashraf Bor'i, Mahmoud A Al-Aswad, Ahmed Abdelwahab Saad, Dina Hamada, Ashraf Mahrous
PURPOSE: To evaluate the outcome of 23 G PPV and ILM peeling with 14% C3F8 compared with silicone oil tamponade in cases of TMHs without spontaneous closure. METHODS: A retrospective comparative study included 33 eyes with TMHs; 7 eyes healed spontaneously, and the remaining 26 eyes have been treated with PPV and ILM peeling. Silicone oil was used as a tamponade for children or adults who refused to adopt face-down position (10 cases). In all other cases (16 cases), 14% C3F8 was used...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811934/the-estimates-of-retinal-ganglion-cell-counts-performed-better-than-isolated-structure-and-functional-tests-for-glaucoma-diagnosis
#7
Bruno L B Esporcatte, Andrea C Kara-José, Luiz Alberto S Melo, Luciano M Pinto, Ivan M Tavares
PURPOSE: To evaluate the diagnostic accuracy of retinal ganglion cell (RGC) counts as estimated by combining data from standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT). METHODS: Healthy individuals and glaucoma patients were included in this cross-sectional study. All eyes underwent 24-2 SITA SAP and structural imaging tests. RGC count estimates were obtained using a previously described algorithm, which combines estimates of RGC numbers from SAP sensitivity thresholds and SD-OCT retinal nerve fiber layer (RNFL) average thickness...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28808586/quality-of-vision-after-deep-anterior-lamellar-keratoplasty-fluid-dissection-compared-to-penetrating-keratoplasty-for-the-treatment-of-keratoconus
#8
Islam Mahmoud Hamdi, Momen Mahmoud Hamdi
PURPOSE: To compare the visual quality of patients with keratoconus who underwent penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) with fluid dissection. DESIGN: Cross-sectional, observational study. METHODS: Twelve eyes that underwent PKP (PKP group) were compared to 24 eyes that underwent DALK (DALK group) after complete removal of sutures and stability of refraction. Visual, refractive, corneal topographic, corneal aberrometry, and ocular aberrometry parameters were compared for both groups...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28804648/inhibition-of-rho-kinase-induces-antioxidative-molecules-and-suppresses-reactive-oxidative-species-in-trabecular-meshwork-cells
#9
Tomokazu Fujimoto, Toshihiro Inoue, Saori Ohira, Nanako Awai-Kasaoka, Takanori Kameda, Miyuki Inoue-Mochita, Hidenobu Tanihara
PURPOSE: To investigate the effect of rho kinase inhibitors on oxidative stress in trabecular meshwork (TM) cells. METHODS: TM cells were isolated from the eyes of cynomolgus monkeys. Y-27632 and menadione were used to inhibit rho kinase and induce production of reactive oxygen species (ROS), respectively. The cynomolgus monkey array and 12,613 probes were used in DNA microarray analysis, and the affected genes were categorized using gene ontology analysis. The mRNA levels of the target genes were confirmed by real-time RT-PCR...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28804647/y-split-recession-of-the-medial-rectus-muscle-as-a-secondary-and-or-unilateral-procedure-in-the-treatment-of-esotropia-with-distance-near-disparity
#10
Monika Wipf, Siegfried Priglinger, Anja Palmowski-Wolfe
INTRODUCTION: In esotropia with larger angles > near than at distance, splitting of the medial rectus muscle has been suggested as a treatment option. Previous reports of bilateral medial rectus Y-splitting as a first intervention showed a reduction of the distance/near disparity with fewer side effects compared to posterior fixation surgery. We address whether a medial rectus Y-splitting as a secondary and/or a unilateral procedure also reduce distance/near disparity. MATERIALS AND METHODS: We retrospectively reviewed the charts of four patients undergoing Y-split recession as a second and/or unilateral surgery...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28804646/glaucoma-quality-of-life
#11
EDITORIAL
Antonio Maria Fea, Fritz Hengerer, Carlo Lavia, Leon Au
No abstract text is available yet for this article.
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28804645/risk-factors-affecting-the-severity-of-full-term-neonatal-retinal-hemorrhage
#12
Zhang Yanli, Zhao Qi, Lin Yu, Guo Haike
OBJECTIVE: The purpose of this study was to explore the underlying clinical factors associated with the degree of retinal hemorrhage (RH) in full-term newborns. METHODS: A total of 3054 full-term infants were included in this study. Eye examinations were performed with RetCamIII within one week of birth for all infants. Maternal, obstetric, and neonatal parameters were compared between newborns with RH and controls. The RH group was divided into three sections (I, II, and III) based on the degree of RH...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28791181/results-of-endoscopic-dacryocystorhinostomy-under-local-anesthesia-with-minimal-sedation
#13
Woong Chul Choi, Ji-Sun Paik, Sang Hee Doh
PURPOSE: We evaluated the tolerability and efficacy of endoscopic dacryocystorhinostomy (Endo-DCR) in patients treated in the leaning position and under local anesthesia with minimal sedation (LAS). STUDY DESIGN: Questionnaire to determine subjective success of Endo-DCR. METHODS: From May 2013 to August 2014, a total of 95 eyes with epiphora presented to the Myoung Eye Plastic Surgery Clinic in Seoul, Korea, and were treated with Endo-DCR under LAS...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28791180/the-influence-of-lunar-phases-on-complications-in-cataract-surgery-an-analysis-of-16-965-patients
#14
Eva-Maria Faschinger, Pia Veronika Vécsei-Marlovits, Dieter Franz Rabensteiner, Birgit Weingessel
PURPOSE: Popular beliefs exert an impact of lunar phases on elective surgery. The aim of our study was to evaluate potential correlations between complications in cataract surgery and the phases of the moon during its passage through the zodiac and Fridays that fall on the 13th. METHODS: Patients with complications during cataract surgery were extracted retrospectively from the clinical database from 2010 to 2014. The dates of surgeries were viewed in relation to the phase and the position of the moon (sign of the zodiac)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28785483/peripheral-ulcerative-keratitis-associated-with-autoimmune-disease-pathogenesis-and-treatment
#15
REVIEW
Yan Cao, Wensong Zhang, Jie Wu, Hong Zhang, Hongyan Zhou
Peripheral ulcerative keratitis (PUK) is type of crescent-shaped inflammatory damage that occurs in the limbal region of the cornea. PUK is always combined with an epithelial defect and the destruction of the peripheral corneal stroma. PUK may have a connection to systemic conditions, such as long-standing rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Wegener granulomatosis (WG), relapsing polychondritis, classic polyarteritis nodosa and its variants, microscopic polyangiitis, and Churg-Strauss syndrome...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28785482/vitreous-substitutes-old-and-new-materials-in-vitreoretinal-surgery
#16
REVIEW
Camilla Alovisi, Claudio Panico, Ugo de Sanctis, Chiara M Eandi
Recent developments in vitreoretinal surgery have increased the need for suitable vitreous substitutes. A successful substitute should maintain all the physical and biochemical properties of the original vitreous, be easy to manipulate, and be long lasting. Substitutes can be gaseous or liquid, both of which have associated advantages and disadvantages related to their physical properties and use. Furthermore, new surgical techniques with smaller vitreoretinal instruments have driven the use of more viscous substitutes...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28785481/exclusive-use-of-air-as-gas-tamponade-in-rhegmatogenous-retinal-detachment
#17
Kang Yeun Pak, Seok Jae Lee, Han Jo Kwon, Sung Who Park, Ik Soo Byon, Ji Eun Lee
PURPOSE: To investigate outcomes of vitrectomy for rhegmatogenous retinal detachment (RRD) using air exclusively as the gas tamponade. METHODS: This retrospective, interventional, consecutive case series involved reviewing medical records of patients that underwent vitrectomy and gas tamponade for RRD between January 2013 and December 2015. Patients whose eyes were treated exclusively with air tamponade since July 2014 were assigned to the air group, while those treated with heterogeneous gas agents before June 2014 were assigned to the control group...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28781891/vascular-occlusions-following-ocular-surgical-procedures-a-clinical-observation-of-vascular-complications-after-ocular-surgery
#18
Charlotte Fischer, Anne Bruggemann, Annette Hager, Josep Callizo Planas, Johann Roider, Hans Hoerauf
BACKGROUND: Ocular vascular occlusions following intraocular procedures are a rare complication. We report a case series of patients with retinal vascular occlusions or anterior ischemic optic neuropathy (AION) after anterior and posterior segment surgery and demonstrate possible risk factors. METHODS: Observational case series. RESULTS: In ten patients, vascular occlusions were observed within ten weeks after intraocular surgery: branch retinal arterial occlusion (BRAO) (n = 2), central retinal artery occlusion (CRAO) (n = 2), central retinal vein occlusion (CRVO) (n = 1), branch retinal vein occlusion (BRVO) (n = 1), anterior ischemic optic neuropathy (AION) (n = 3), and combined central artery and vein occlusion (n = 1)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28770109/ocular-adverse-effects-of-intravitreal-bevacizumab-are-potentiated-by-intermittent-hypoxia-in-a-rat-model-of-oxygen-induced-retinopathy
#19
Jeffrey J Tan, Charles L Cai, Eric M Shrier, Lois McNally, Douglas R Lazzaro, Jacob V Aranda, Kay D Beharry
Intravitreal bevacizumab (Avastin) use in preterm infants with retinopathy of prematurity is associated with severe neurological disabilities, suggesting vascular leakage. We examined the hypothesis that intermittent hypoxia (IH) potentiates intravitreal Avastin leakage. Neonatal rats at birth were exposed to IH from birth (P0)-P14. At P14, the time of eye opening in rats, a single dose of Avastin (0.125 mg) was injected intravitreally into the left eye. Animals were placed in room air (RA) until P23 or P45 for recovery (IHR)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28770108/the-combination-of-ketorolac-with-local-anesthesia-for-pain-control-in-day-care-retinal-detachment-surgery-a-randomized-controlled-trial
#20
Xiaohong Chen, Bingqian Liu, Xiaoling Liang, Jiaqing Li, Tao Li, Yonghao Li, Xiling Yu, Cancan Lyu, Xiujuan Zhao, Silvia Tanumiharjo, Chenjin Jin, Lin Lu
This study aims to evaluate the efficacy of ketorolac with local anesthesia compared to local anesthesia alone for perioperative pain control in day care retinal detachment surgery. The randomized controlled trial included 59 eyes of 59 participants for retinal detachment surgery who were randomly assigned (1 : 1) into the ketorolac (K) group and control (C) group. All participants underwent conventional local anesthesia while patients in the K group received an extra administration of preoperative ketorolac...
2017: Journal of Ophthalmology
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