journal
MENU ▼
Read by QxMD icon Read
search

Journal of Tropical Medicine

journal
https://www.readbyqxmd.com/read/29138642/observation-of-blood-donor-recipient-malaria-parasitaemia-patterns-in-a-malaria-endemic-region
#1
Jamilu Abdullahi Faruk, Gboye Olufemi Ogunrinde, Aisha Indo Mamman
Background: Asymptomatic malaria parasitaemia has been documented in donor blood in West Africa. However, donated blood is not routinely screened for malaria parasites (MPs). The present study therefore aimed to document the frequency of blood transfusion-induced donor-recipient malaria parasitaemia patterns, in children receiving blood transfusion in a tertiary health-centre. Methodology: A cross-sectional, observational study involving 140 children receiving blood transfusion was carried out...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29138641/naturally-acquired-antibody-responses-to-a-synthetic-malaria-antigen-as202-11
#2
Rebeka Nazareth, Pius Horumpende, Tolbert Sonda, Arnold Ndaro, Edson Mollel, Eliakim Paul, Emmanuel Athanase, Jaffu Chilongola
Background: A major challenge to malaria vaccine development is identification of protective epitopes and respective protective immune responses. Objective: To characterize naturally acquired Immunoglobulin G (IgG) responses to the synthetic peptide AS202.11, a malaria vaccine candidate. Methodology: This community based cross-sectional study enrolled 320 participants aged 1 year and above. Demographic information was recorded through interviews...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29138640/prevalence-of-soil-transmitted-helminthiases-and-schistosomiasis-in-preschool-age-children-in-mwea-division-kirinyaga-south-district-kirinyaga-county-and-their-potential-effect-on-physical-growth
#3
Stephen Sifuna Wefwafwa Sakari, Amos K Mbugua, Gerald M Mkoji
Intestinal parasitic infections can significantly contribute to the burden of disease, may cause nutritional and energetic stress, and negatively impact the quality of life in low income countries of the world. This cross-sectional study done in Mwea irrigation scheme, in Kirinyaga, central Kenya, assessed the public health significance of soil-transmitted helminthiases (STH), schistosomiasis, and other intestinal parasitic infections, among 361 preschool age children (PSAC) through fecal examination, by measuring anthropometric indices, and through their parents/guardians, by obtaining sociodemographic information...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29123551/discovery-of-antimalarial-drugs-from-streptomycetes-metabolites-using-a-metabolomic-approach
#4
REVIEW
Siti Junaidah Ahmad, Mohd Badrin Hanizam Abdul Rahim, Syarul Nataqain Baharum, Mohd Shukri Baba, Noraziah Mohamad Zin
Natural products continue to play an important role as a source of biologically active substances for the development of new drug. Streptomyces, Gram-positive bacteria which are widely distributed in nature, are one of the most popular sources of natural antibiotics. Recently, by using a bioassay-guided fractionation, an antimalarial compound, Gancidin-W, has been discovered from these bacteria. However, this classical method in identifying potentially novel bioactive compounds from the natural products requires considerable effort and is a time-consuming process...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28828009/liver-fibrosis-and-hepatitis-b-coinfection-among-art-na%C3%A3-ve-hiv-infected-patients-at-a-tertiary-level-hospital-in-northwestern-tanzania-a-cross-sectional-study
#5
Semvua B Kilonzo, Daniel W Gunda, Flora Kashasha, Bonaventura C Mpondo
BACKGROUND: Liver fibrosis which is a common complication of chronic hepatitis B infection is rarely diagnosed in low-resource countries due to limited capacity to perform biopsy studies. Data on the utilization of noninvasive techniques which are feasible for diagnosis of liver fibrosis in these settings among HIV-infected patients is scarce. The objective of this study was to establish the magnitude of liver fibrosis by using both aspartate-aminotransferase-to-platelets ratio and fibrosis-4 scores with associated hepatitis B coinfection among antiretroviral therapy naïve HIV-infected patients...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28808447/predictors-for-mortality-among-multidrug-resistant-tuberculosis-patients-in-tanzania
#6
Edson W Mollel, Jaffu O Chilongola
PROBLEM: Factors related to MDRTB mortality in Tanzania have not been adequately explored and reported. OBJECTIVES: To determine demographic, clinical, radiographic, and laboratory factors associated with MDRTB mortality in a Tanzanian TB Referral Hospital. METHODOLOGY: This was a cross-sectional study with 193 participants. Demographic, clinical, laboratory, and radiological data were collected, and their associations with mortality among MDRTB patients were determined...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28740517/dengue-virus-ns1-protein-as-a-diagnostic-marker-commercially-available-elisa-and-comparison-to-qrt-pcr-and-serological-diagnostic-assays-currently-used-by-the-state-of-florida
#7
Jason H Ambrose, Shamala Devi Sekaran, Azliyati Azizan
BACKGROUND: The proper management of patients infected with dengue virus requires early detection. Here, real-time molecular assays have proven useful but have limitations, whereas ELISAs that detect antibodies are still favored but results are obtained too late to be of clinical value. The production of DENV NS1 peaks early during infection and its detection can combine the advantages of both diagnostic approaches. METHODS: This study compared assays currently used for detecting DENV infection at the Florida Department of Health including anti-DENV IgM and IgG ELISAs as well as qRT-PCR, against a commercially available DENV NS1 ELISA...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28717366/interrelationship-between-climatic-ecologic-social-and-cultural-determinants-affecting-dengue-emergence-and-transmission-in-puerto-rico-and-their-implications-for-zika-response
#8
REVIEW
Angela Matysiak, Amira Roess
OBJECTIVE: The global resurgence of dengue has been attributed to rapid population growth, urban expansion, increased air travel, globalization, and climate change. Dengue is now endemic in Puerto Rico. Puerto Rico is at risk for Zika, another emerging arbovirus. The interrelationship between climatic, ecological, social, and cultural factors that affect dengue and other arboviruses' transmission is understudied. DESIGN: The objective of this systematic review is to examine the interrelationship between climatic, ecological, social, and cultural factors on dengue transmission in Puerto Rico and to draw lessons for Zika response...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28694828/prevalence-and-risk-factors-of-delayed-sputum-conversion-among-patients-treated-for-smear-positive-ptb-in-northwestern-rural-tanzania-a-retrospective-cohort-study
#9
Daniel W Gunda, Igembe Nkandala, Godfrey A Kavishe, Semvua B Kilonzo, Rodrick Kabangila, Bonaventura C Mpondo
INTRODUCTION: Smear positive TB carries high morbidity and mortality. The TB treatment aims at sputum conversion by two months of antituberculous. Patients who delay sputum conversion remain potentially infectious, with risk of treatment failure, drug resistance, and mortality. Little is known about the magnitude of this problem in our setting. This study was designed to determine the prevalence and risk factors of delayed sputum conversion in northwestern rural part of Tanzania. METHODS: This was a retrospective cohort study involving smear positive TB patients at Sengerema DDH in 2015...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28634494/antiviral-activity-of-fridericia-formosa-bureau-l-g-lohmann-bignoniaceae-extracts-and-constituents
#10
Geraldo Célio Brandão, Erna G Kroon, José D Souza Filho, Alaíde Braga Oliveira
A phytochemical study of Fridericia formosa (Bignoniaceae) ethanol extracts of leaves, stems, and fruits was guided by in vitro assays against vaccinia virus Western Reserve (VACV-WR), human herpes virus 1 (HSV-1), murine encephalomyocarditis virus (EMCV), and dengue virus type 2 (DENV-2) by the MTT method. All the ethanol extracts were active against DENV-2, HSV-1, and VACV-WR with best results for the fruits extract against DENV-2 (SI > 38.2). For VACV-WR and HSV-1, EC50 values > 200 μg mL(-1) were determined, while no inhibition of the cytopathic effect was observed with EMCV...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28630631/urinalysis-and-clinical-correlations-in-patients-with-p-vivax-or-p-falciparum-malaria-from-colombia
#11
Alberto Tobón-Castaño, Sebastián Barrera Escobar, Cecilia Giraldo Castro
BACKGROUND: Urinalysis is a poorly reviewed diagnostic tool in malaria patients; its application can show the presence of severe malaria. METHODS: Urinalysis was performed in a total of 620 patients diagnosed with malaria by thick blood smear; complications were classified according to WHO major criteria for severity and minor criteria according to the Colombian malaria guideline. RESULTS: Severe or moderate clinical complications were diagnosed in 31...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28588624/distribution-of-parasites-detected-in-stool-samples-of-patients-in-le-dantec-university-hospital-of-dakar-senegal-from-2011-to-2015
#12
Khadim Diongue, Mouhamadou Ndiaye, Mame Cheikh Seck, Mamadou Alpha Diallo, Yaye Dié Ndiaye, Aïda Sadikh Badiane, Daouda Ndiaye
To identify the parasites responsible for intestinal parasitic infections diagnosed at Le Dantec University Hospital of Dakar, distribution of parasites detected in stool samples of patients was studied. From 2011 to 2015, 2578 patients were included in the study. A direct examination and Ritchie technique were performed as parasite search techniques. In total, 408 samples were positive showing 440 intestinal parasites; this corresponds to prevalence of 15.8%. Parasites were detected in monoparasitism (85.7%) and multiparasitism (14...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28567060/analysing-the-influence-of-health-insurance-status-on-peoples-health-seeking-behaviour-in-rural-ghana
#13
Benedict Osei Asibey, Seth Agyemang
This paper examines the influence of health insurance status on healthcare use in rural Ghana using 286 sampled respondents from four rural communities in the Bekwai Municipality. Data were obtained using structured interview and Pearson's Chi square and bivariate regressions were used to analyse data. The results show low healthcare utilization among study participants, with most respondents having irregular use (43.5%) or rare use (43.3%). Respondents with health insurance utilized healthcare more than those without health insurance, the results being statistically significant (df = 4; n = 283, p = 0...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28458694/submicroscopic-and-asymptomatic-congenital-infection-by-plasmodium-vivax-or-p-falciparum-in-colombia-37-cases-with-placental-histopathology-and-cytokine-profile-in-maternal-and-placental-blood
#14
Olga María Agudelo-García, Eliana María Arango-Flórez, Jaime Carmona-Fonseca
Problem. Congenital plasmodial infection (CPI) is a rare event, which has been little studied in Colombia. Objective. To measure the frequency of CPI and to describe the immune and histological characteristics in maternal blood and placentas when CPI occurs. Methodology. A cross-sectional study was carried out in northwest Colombia. A sample size of 39 unit analysis (a unit of analysis corresponds to the cord, placenta, and peripheral blood of a pregnant woman) was calculated using epidemiological and statistical parameters...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28392806/epidemiological-characteristics-of-dengue-disease-in-latin-america-and-in-the-caribbean-a-systematic-review-of-the-literature
#15
REVIEW
Jaime Rafael Torres, Tomás Agustín Orduna, Maricela Piña-Pozas, Daniela Vázquez-Vega, Elsa Sarti
Dengue, an important mosquito-borne virus transmitted mainly by Aedes aegypti, is a major public health issue in Latin America and the Caribbean. National epidemiological surveillance systems, usually based on passive detection of symptomatic cases, while underestimating the true burden of dengue disease, can provide valuable insight into disease trends and excess reporting and potential outbreaks. We carried out a systematic review of the literature to characterize the recent epidemiology of dengue disease in Latin America and the English-speaking and Hispanic Caribbean Islands...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28386286/a-thermostabilized-one-step-pcr-assay-for-simultaneous-detection-of-klebsiella-pneumoniae-and-haemophilus-influenzae
#16
Nur Amalina Khazani, Nik Zuraina Nik Mohd Noor, Chan Yean Yean, Habsah Hasan, Siti Suraiya, Suharni Mohamad
Klebsiella pneumoniae and Haemophilus influenzae are two common pathogens associated with respiratory tract infections. The identification of these pathogens using conventional molecular diagnostic tests requires trained personnel, cold-chain transportation, and storage-dependance, which does not render them user-friendly. The aim of this study was to develop a thermostabilized, cold-chain-free, one-step multiplex PCR for simultaneous detection of K. pneumoniae and H. influenzae. The multiplex PCR assay was designed to amplify the php gene of K...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28348602/incidence-and-predictors-of-antiretroviral-treatment-modification-in-hiv-infected-adults-a-brazilian-historical-cohort-from-2001-to-2010
#17
Letícia Penna Braga, Cássia Cristina Pinto Mendicino, Edna Afonso Reis, Ricardo Andrade Carmo, Cristiane Menezes de Pádua
This study estimated the incidence of and time to first antiretroviral therapy (ART) modification. This longitudinal analysis comprised a sample of 236 patients from three HIV/AIDS referral centers in Belo Horizonte, Brazil-part of a major historical cohort. Inclusion criteria were as follows: having been treatment-naive patient ≥18 years old who initiated ART between 2001 and 2005 in these three referral centers. The main endpoint was time to first ART modification. Patients were followed up for five years, covering the period 2001-2010, during which time Pearson's chi-square test was performed to compare ART modification between groups...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28348601/diversity-of-leptospira-spp-in-rats-and-environment-from-urban-areas-of-sarawak-malaysia
#18
Chai Fung Pui, Lesley Maurice Bilung, Kasing Apun, Lela Su'ut
Various prevalence studies on Leptospira in animals and humans, as well as environmental samples, had been conducted worldwide, including Malaysia. However, limited studies have been documented on the presence of pathogenic, intermediate, and saprophytic Leptospira in selected animals and environments. This study was therefore conducted to detect Leptospira spp. in rats, soil, and water from urban areas of Sarawak using the polymerase chain reaction (PCR) method. A total of 107 rats, 292 soil samples, and 324 water samples were collected from April 2014 to February 2015...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28331496/nitazoxanide-in-acute-rotavirus-diarrhea-a-randomized-control-trial-from-a-developing-country
#19
Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, Rashmi Ranjan Das
Background. Acute diarrhea is one of the leading causes of childhood mortality, with rotavirus being an important pathogen. Nitazoxanide, an antiparasitic agent, has been shown to inhibit rotavirus. Objective. This double-blind, randomized trial was designed to study the role of nitazoxanide in acute rotavirus diarrhea. Methods. Of 174 children (12 months to 5 years) with acute diarrhea, 50 rotavirus positive cases were randomized. The intervention group received syrup nitazoxanide twice daily (100 mg in 12-47 months, 200 mg in ≥4 yr) for 3 days along with standard treatment of diarrhea...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28321260/loop-mediated-isothermal-amplification-test-for-trypanosoma-gambiense-group-1-with-stem-primers-a-molecular-xenomonitoring-test-for-sleeping-sickness
#20
Zablon K Njiru, Cecilia K Mbae, Gitonga N Mburugu
The World Health Organization has targeted Human African Trypanosomiasis (HAT) for elimination by 2020 with zero incidence by 2030. To achieve and sustain this goal, accurate and easy-to-deploy diagnostic tests for Gambian trypanosomiasis which accounts for over 98% of reported cases will play a crucial role. Most needed will be tools for surveillance of pathogen in vectors (xenomonitoring) since population screening tests are readily available. The development of new tests is expensive and takes a long time while incremental improvement of existing technologies that have potential for xenomonitoring may offer a shorter pathway to tools for HAT surveillance...
2017: Journal of Tropical Medicine
journal
journal
42866
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"