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Journal of Tropical Medicine

Maria A Loroño-Pino, Ana Uitz-Mena, Claudia M Carrillo-Solís, Rocío J Zapata-Gil, Dora M Camas-Tec, Lourdes G Talavera-Aguilar, Rosa C Cetina-Trejo, Luis F Flores-Flores, María C Puc-Tinal, Clara Caamal-Jiménez, Guadalupe Reyes-Solís, Julián E García-Rejón, Karla Saavedra-Rodriguez, Lars Eisen, Thomas J Keefe, William C Black Iv, Barry J Beaty
Dengue, chikungunya, yellow fever, and Zika viruses transmitted by Aedes aegypti mosquitoes are major public health threats in the tropical and subtropical world. In México, construction of large tracts of "fraccionamientos" high density housing to accommodate population growth and urbanization has provided fertile ground for Ae. aegypti -transmitted viruses. We investigated the utility of pyrethroid-treated window curtains to reduce both the abundance of Ae. aegypti and to prevent dengue virus (DENV) transmission in fraccionamiento housing...
2018: Journal of Tropical Medicine
James Osei-Yeboah, Sylvester Yao Lokpo, Francis Abeku Ussher, Verner Ndudiri Orish, Abdul-Wahab Mawuko Hamid, Mavis Puopelle Dakorah, Tibemponi Ntoni, Emmanuel Agbeko Nani, Felix Ayroe, Daniel Adigbli
The study was aimed at comparing the estimation of the burden and trends (2012-2016) of Human Immunodeficiency Virus (HIV) and Syphilis infections by the national Sentinel Survey vis-à-vis the use of population-based studies at a single urban site (Municipal Hospital) in Ho, the Volta Region of Ghana. Using blood donors as a proxy of the asymptomatic adult population, a retrospective analysis of secondary data on HIV and Syphilis testing was conducted using Ho Municipal Hospital's archives comprising 4,180 prospective blood donors...
2018: Journal of Tropical Medicine
Gaspar Peniche-Lara, Bertha Jimenez-Delgadillo, Claudia Munoz-Zanzi, María Cárdenas-Marrufo, Carlos Pérez-Osorio, Juan Arias-León
In the state of Yucatan, Mexico, rickettsiosis has become a common vector-borne disease in the general population. Ectoparasite species such as Rhipicephalus sanguineus and Amblyomma mixtum have been identified as Rickettsia vectors in Yucatan by studies focused on the wild animal population in rural areas. There have been studies that have tried to determine the presence of Rickettsia species in ectoparasites collected in Yucatan, but these studies did not include marginalized areas, where living in close contact with domestic and peridomestic animals that carry ectoparasites is a high-risk factor for acquiring rickettsial infection or many other vector-borne diseases...
2018: Journal of Tropical Medicine
Surang Leelawat, Kawin Leelawat
Background: Hydnocarpus anthelminthicus is primarily used as a traditional medicine for the treatment of leprosy. Previous studies demonstrated that the clinical course of leprosy and the susceptibility to mycobacteria are recognized by the immune response of the host. The current study aims to investigate the effect of H. anthelminthicus seed oil and extracts on the secretion of cytokines from PBMCs involved in immune regulation. Methods: PBMCs from healthy volunteers were cultured and treated with LPS and H...
2018: Journal of Tropical Medicine
Gertrude Namale, Onesmus Kamacooko, Alison Kinengyere, Laetitia Yperzeele, Patrick Cras, Edward Ddumba, Janet Seeley, Robert Newton
Introduction: In sub-Saharan Africa (SSA), there is a significant burden of ischemic stroke (IS) and hemorrhagic stroke (HS), although data on risk factors for each type are sparse. In this systematic review we attempt to characterize the risk factors. Methods: We systematically reviewed (PubMed, EMBASE, WHOLIS, Google Scholar, Wiley online, and the Cochrane Central Register of Controlled Trials (CENTRAL)) case-control studies and case series from 1980 to 2016 that reported risk factors for IS and/or HS in SSA...
2018: Journal of Tropical Medicine
Grace Frimpong, Kwabena Ofori-Kwakye, Noble Kuntworbe, Kwame Ohene Buabeng, Yaa Asantewaa Osei, Mariam El Boakye-Gyasi, Ofosua Adi-Dako
The quality of 68 samples of 15 different essential children's medicines sold in licensed medicine outlets in the Ashanti Region, Ghana, was evaluated. Thirty-two (47.1%) of the medicines were imported, mainly from India (65.6%) and the United Kingdom (28.1%), while 36 (52.9%) were locally manufactured. The quality of the medicines was assessed using content of active pharmaceutical ingredient (API), pH, and microbial limit tests, and the results were compared with pharmacopoeial standards. Twenty-six (38.2%) of the samples studied passed the official content of API test while 42 (61...
2018: Journal of Tropical Medicine
Roland Nnaemeka Okoro, Muslim Olakunle Jamiu
In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to evaluate prescribers' adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotics at a tertiary hospital in Nigeria...
2018: Journal of Tropical Medicine
Akram Layegh Gigloo, Bahador Sarkari, Zahra Rezaei, Gholam Reza Hatam, Mohammad Hassan Davami
The current study aimed to evaluate the seroprevalence of visceral leishmaniasis in asymptomatic healthy children in a rural area of Fars province, Southern Iran. Blood samples were taken from 617 asymptomatic healthy children and serum samples along with buffy coat were separated from the blood. The serum samples were assessed for antibodies against Leishmania infantum by an indirect ELISA and the buffy coats were tested for the presence of L. infantum DNA by molecular method. Of the 617 recruited children, 297 (48...
2018: Journal of Tropical Medicine
Jose Figueredo-Silva, Joaquim Norões, Gerusa Dreyer
Background: In endemic areas, lymphangiectasia is the fundamental alteration to live Wuchereria bancrofti adult worms which, in adult males, are usually found in the lymphatic vessels of the spermatic cord; accordingly, hydrocele/filaricele is the most common clinical manifestation of bancroftian filariasis. The pathogenic role of the lymphatic endothelial cells (LECs) and the status of mesothelial cells (MCs) samples of the parietal layer (PL) of the tunica vaginalis testis were examined...
2018: Journal of Tropical Medicine
Babamale Olarewaju Abdulkareem, Kolawole Olasunkanmi Habeeb, Abdulganiyu Kazeem, Abdulkareem Olaitan Adam, Ugbomoiko Uade Samuel
Urogenital schistosomiasis is a chronic parasitic disease that causes severe morbidity among schoolchildren in many poor-resource communities in Nigeria. We investigated the prevalence, intensity, and risk factors of the infection in three communities of Kwara State to ascertain the current status of the disease. Of the 724 urine samples screened, using filtration method, 332 (45.6%) school-aged children were infected with average intensity and mean population eggs load of 127.9 eggs/10 ml of urine and 0...
2018: Journal of Tropical Medicine
Muh Taslim, A A Arsunan, Hasanuddin Ishak, Sudirman Nasir, Andi Nilawati Usman
The objective of this research was to investigate serotype diversity pattern of dengue hemorrhagic fever virus by using real-time-polymerase chain reaction (RT-PCR) method. It was an explorative laboratory research in endemic dengue fever area in South Sulawesi Province, Indonesia, that is, Makassar municipality and Maros and Gowa region. Serological examination was carried out using real-time-polymerase chain reaction (RT-PCR) method to determine the serotype of dengue virus. The data showed that, of 30 patients, 20 patients (66...
2018: Journal of Tropical Medicine
Sri Novianty, Yazid Dimyati, Syahril Pasaribu, Ayodhia Pitaloka Pasaribu
Background: Disease burden from soil-transmitted helminthiasis (STH) is mainly attributed to its chronic and insidious impact on health and quality of life. Strategy recommended by World Health Organization (WHO) to control it was previously focused on school-aged children, but now preschool-aged children are involved. This study was intended to determine STH infection risk factors in preschool children. Methods: A cross-sectional study was conducted in Suka Village, North Sumatera, Indonesia, from October to December 2016...
2018: Journal of Tropical Medicine
M N Wogu, F O Nduka
The World Health Organization's policy on laboratory test of all suspected malaria cases before treatment has not yielded significant effects in several rural areas of Sub-Saharan Africa due to inadequate diagnostic infrastructure, leading to high morbidity and mortality rates. A cross-sectional randomized study was conducted to evaluate the validity of clinical malaria diagnosis through comparison with microscopy and rapid diagnostic test kits (RDTs) using 1000 consenting outpatients of a tertiary hospital in Nigeria...
2018: Journal of Tropical Medicine
Sashini D Perera, Uthpala A Jayawardena, Chanika D Jayasinghe
Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue. Though, E. hirta has been extensively investigated for numerous bioactivities, limited studies have been conducted on the antidengue activity. Thus, the present study provides a comprehensive review of studies conducted on the antidengue activity of E. hirta . A systematic literature survey was carried out in scientific databases, PubMed®, Scopus, and Google Scholar, for research carried on the antidengue activity of E...
2018: Journal of Tropical Medicine
Timothy S Mamba, Cecilia K Mbae, Johnson Kinyua, Erastus Mulinge, Gitonga Nkanata Mburugu, Zablon K Njiru
Background. Cryptosporidium is a protozoan parasite and a major cause of diarrhea in children and immunocompromised patients. Current diagnostic methods for cryptosporidiosis such as microscopy have low sensitivity while techniques such as PCR indicate higher sensitivity levels but are seldom used in developing countries due to their associated cost. A loop-mediated isothermal amplification (LAMP) technique, a method with shorter time to result and with equal or higher sensitivity compared to PCR, has been developed and applied in the detection of Cryptosporidium species...
2018: Journal of Tropical Medicine
Teguh Hari Sucipto, Tomohiro Kotaki, Kris Cahyo Mulyatno, Siti Churrotin, Amaliah Labiqah, Soegeng Soegijanto, Masanori Kameoka
Dengue virus (DENV) infection is a major health issue in tropical and subtropical areas. Indonesia is one of the biggest dengue endemic countries in the world. In the present study, the phylogenetic analysis of DENV in Bangkalan, Madura Island, Indonesia, was performed in order to obtain a clearer understanding of its dynamics in this country. A total of 359 blood samples from dengue-suspected patients were collected between 2012 and 2014. Serotyping was conducted using a multiplex Reverse Transcriptase-Polymerase Chain Reaction and a phylogenetic analysis of E gene sequences was performed using the Bayesian Markov chain Monte Carlo (MCMC) method...
2018: Journal of Tropical Medicine
Yos Adi Prakoso, Kurniasih
The aim of this study is to explore the effect of topical application of Aloe vera on skin wound healing. Thirty-six male Sprague-Dawley rats weighing 150-200 grams were divided into four groups. All groups were anesthetized, shaved, and exposed to round full-thickness punch biopsy on the back: group I (control); group II (treated with 1% Aloe vera cream); group III (treated with 2% Aloe vera cream); and group IV (treated with madecassol®). The treatments were given once a day. Macroscopic and microscopic examination were observed at 5, 10, and 15 days after skin biopsy...
2018: Journal of Tropical Medicine
Semvua B Kilonzo, Daniel W Gunda, Bonaventura C T Mpondo, Fatma A Bakshi, Hyasinta Jaka
Hepatitis B is one of the most common infectious diseases in the world with high prevalence in most of sub-Saharan Africa countries. The complexity in its diagnosis and treatment poses a significant management challenge in the resource-limited settings including Tanzania, where most of the tests and drugs are either unavailable or unaffordable. This mini review aims at demonstrating the current status of the disease in the country and discussing the concomitant challenges in diagnosis, treatment, and prevention...
2018: Journal of Tropical Medicine
Sahle Asfaw, Fikre Enquselassie, Yifokire Tefera, Muluken Gizaw, Samson Wakuma, Messay Woldemariam
Background: Chronic respiratory symptoms including chronic cough, chronic phlegm, wheezing, shortness of breath, and chest pain are manifestations of respiratory problems which are mainly evolved as a result of occupational exposures. This study aims to assess determinants of chronic respiratory symptoms among pharmaceutical factory workers. Methods: A case control study was carried out among 453 pharmaceutical factory workers with 151 cases and 302 controls. Data was collected using pretested and structured questionnaire...
2018: Journal of Tropical Medicine
Jones Asafo Akowuah, Peter Agyei-Baffour, Dadson Awunyo-Vitor
Access to quality healthcare still remains a major challenge in the efforts at reversing maternal morbidity and mortality. Despite the availability of established maternal health interventions, the health of the expectant mother and the unborn child remains poor due to low utilisation of interventions. The study examined the socioeconomic determinants of antenatal care utilisation in peri-urban Ghana using pregnant women who are in their third trimester. Two-stage sampling technique was used to sample 200 pregnant women who were in their third trimester from the District Health Information Management System software...
2018: Journal of Tropical Medicine
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