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Middle East African Journal of Ophthalmology

Jerry A Shields, Carol L Shields, Sara E Lally, Tatyana Milman, Ralph C Eagle
An 8-year-old girl was referred for an amelanotic iris tumor believed to have enlarged slightly over 3 months, suspicious for juvenile xanthogranuloma (JXG). The affected right eye had a lightly pigmented, vascular iris mass measuring 6 mm in basal dimension and 2 mm in thickness. There were no feeder vessels, seeding, inflammatory cells, or cutaneous abnormalities. Diagnostic fine needle aspiration biopsy (FNAB) was performed, revealing spindle B melanoma cells that were immunoreactive for melanocytic markers HMB45 and Melan-A...
April 2018: Middle East African Journal of Ophthalmology
Justin D Pennington, R Joel Welch, Sara E Lally, Jerry A Shields, Ralph C Eagle, Carol L Shields
Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Molecular analysis revealed the absence of the PAX3/FOXO1 fusion gene, indicating favorable prognosis...
April 2018: Middle East African Journal of Ophthalmology
Meredith A Spencer, R Joel Welch, Carol L Shields
Over recent years, hand-held optical coherence tomography (HH-OCT) has become critical for retinoblastoma diagnosis and management. We report precise HH-OCT findings in a case of sub-millimeter retinoblastoma treated with foveal-sparing indocyanine green-enhanced transpupillary thermotherapy (ICG-TTT). A 2-month-old Caucasian female with bilateral Group B retinoblastoma showed two recurrent macular tumors in the right eye, demonstrating 88 μm and 37 μm of growth to 344 μm and 413 μm in thickness, respectively, on HH-OCT...
April 2018: Middle East African Journal of Ophthalmology
Tahra AlMahmoud, Sean Quinlan-Davidson, Gregory R Pond, Jean Deschênes
PURPOSE: The purpose of this study is to report on treatment outcomes for medium-sized choroidal melanoma treated with Ruthenium-106 (Ru-106) plaque brachytherapy. METHODS: A retrospective case series of 28 patients received Ru-106 brachytherapy treatment for choroidal melanoma. The prescribed tumor dose was 85 Gy to a depth of 5 mm. RESULTS: Median follow-up was 31.2 months. At 12 and 24-month postirradiation, the best corrected visual acuity ≥20/70 (LogMar ≥-0...
April 2018: Middle East African Journal of Ophthalmology
Manar Al Wohaib, Reem Al Ahmadi, Dalal Al Essa, Azza Maktabbi, Rajiv Khandekar, Eman Al Sharif, Hind Al Katan, Silvana Artioli Schellini, Osama Al Shaikh
PURPOSE: Data on basal cell carcinoma (BCC) from the Middle East are deficient. We present the features and management outcomes for BCC over the last 36 years in Saudi Arabia. SUBJECTS AND METHODS: This retrospective chart review included BCC patients diagnosed and treated at Saudi Arabia between 1980 and 2016. Data were collected on patient demographics, clinical and histopathological characteristics of the lesions, management, and follow-up. RESULTS: One hundred and twenty-six patients with BCC were included in this study...
April 2018: Middle East African Journal of Ophthalmology
Victoria M L Cohen, Efthymia Pavlidou, Joanna DaCosta, Amit K Arora, Teressa Szyszko, Mandeep S Sagoo, Peter Szlosarek
PURPOSE: The purpose of this study was to report the results of staging primary uveal melanoma with whole-body (18) fluorodeoxyglucose (FDG) positron-emission tomography/computed tomography (PET/CT) and abdominal ultrasound. MATERIALS AND METHODS: From January 2012, patients with uveal melanoma over 4 mm in thickness were staged with FDG PET/CT and abdominal ultrasound. RESULTS: Over 2 years, 108 patients with medium-to-large melanoma underwent dual imaging...
April 2018: Middle East African Journal of Ophthalmology
Carol L Shields, R Joel Welch, Kunal Malik, Luis A Acaba-Berrocal, Evan B Selzer, Jennifer H Newman, Eileen L Mayro, Alexandru B Constantinescu, Meredith A Spencer, Mark P McGarrey, Austen N Knapp, Alexander E Graf, Alex J Altman, Sean P Considine, Jerry A Shields
PURPOSE: The purpose of this study is to evaluate patients with uveal metastasis based on primary tumor site. METHODS: Retrospective analysis from Wills Eye Hospital, Philadelphia, PA, USA, for uveal metastasis clinical features and outcomes based on the primary tumor site. RESULTS: There were 2214 uveal metastases diagnosed in 1111 consecutive patients. The demographics included mean age of 60 years (median 61 years), Caucasian race (88%), and female gender (64%)...
April 2018: Middle East African Journal of Ophthalmology
Yağmur Seda Yeşiltaş, Ahmet Kaan Gündüz
Idiopathic orbital inflammation (IOI) is a benign inflammatory condition usually confined to the orbit but extraorbital extension can also occur. IOI has been classified into categories including anterior, diffuse, posterior or apical, myositis, and dacryoadenitis. Other rare types of IOI include periscleritis, perineuritis, and focal mass. Diagnosis is based on careful history, clinical findings, computed tomography, and magnetic resonance imaging findings. An orbital biopsy is usually done for accessible orbital lesions such as dacryoadenitis...
April 2018: Middle East African Journal of Ophthalmology
Hany S Hamza, Abdelrahman M Elhusseiny
Uveal melanoma is the most common intraocular malignant tumor, with the choroid being the most common site. Management of choroidal melanoma has evolved greatly over the past years. In the past, the conventional method of treatment was enucleation of the affected eye with a debate regarding the effect of enucleation to promote or prevent metastasis. However, nowadays, there are many therapeutic options available including plaque radiotherapy, proton beam radiotherapy, argon laser photocoagulation, transpupillary thermotherapy, stereotactic radiotherapy using gamma knife, enucleation, and surgical resection of the tumor whether through transscleral approach "Exoresection" or less commonly through internal resection approach "Endoresection...
April 2018: Middle East African Journal of Ophthalmology
Richard Cutler Allen
Incidental orbital masses that are asymptomatic and appear benign are often observed without surgical intervention unless there is a clinical or radiographic change in the mass. There is a burgeoning population of cancer patients with incidental masses that have been detected while under surveillance for metastasis. This population of patients is growing due to a number of reasons, including more extensive imaging, an aging population, and more effective cancer treatments. Closer scrutiny should be applied to these patients, due to the possibility of the mass being an orbital metastasis...
April 2018: Middle East African Journal of Ophthalmology
Ahmet Kaan Gündüz
No abstract text is available yet for this article.
April 2018: Middle East African Journal of Ophthalmology
Sirous Nekooei, Mahsa Sardabi, Mohammad Etezad Razavi, Amirhossein Nekooei, Mohammad Yaser Kiarudi
Orbital floor fractures alone or in conjunction with other facial skeletal fractures are the most commonly encountered midfacial fractures. The technological advances in 3-dimensional (3D) printing allow the physical prototyping of 3D models, so creates an accurate representation of the patient's specific anatomy. A 56-year-old Caucasian man with severe hypoglobus and enophthalmos with an extensive blowout fracture was scheduled for reconstruction. First, 3D physical models were created based on the computed tomography scan datasets from patient...
January 2018: Middle East African Journal of Ophthalmology
Abdulrahman AlDarrab, Rizwan Malik
Aniridia-associated glaucoma is often refractory to medical treatment. Glaucoma drainage device surgery is often considered after failed angle surgery. However, the potential complications of tube surgery in young children are not negligible. The failure rate of conventional trabeculectomy may be high and can require close and multiple postoperative follow-up visits. Here, we describe a child with aniridia who achieved good short-term results with deep sclerectomy. A 14-month-old girl was referred to our unit following bilateral trabeculotomies for aniridia-associated glaucoma and persistent uncontrolled intraocular pressure (IOP) in both eyes...
January 2018: Middle East African Journal of Ophthalmology
Ved Prakash Gupta, Isha Chaudhari
Palmoplantar keratodermas (PPKs) are a rare heterogeneous group of disorders characterized by abnormal thickening of the skin of palms and soles. Ocular manifestations reported with palmer planter keratosis include scleral melanosis, macular deposits, and congenital cataract. We report, for the first time, a case of bilateral keratoconus in a patient with PPK.
January 2018: Middle East African Journal of Ophthalmology
Aliyah Hadi Alameri, Donald Ural Stone
Exposure of the suture after transscleral suture fixation of posterior chamber intraocular lenses is a known late complication that typically requires intervention. Patch grafts of sclera, cornea, or pericardium have been described. We describe a novel autologous scleral flap to cover an exposed 10-0 polypropylene suture. This technique requires no exogenous graft material and avoids the risks of intraocular manipulation of the lens. Every effort should be made to avoid external exposure of the suture, but in cases that develop suture erosion, an autologous scleral flap may be a useful intervention...
January 2018: Middle East African Journal of Ophthalmology
Hosien Shahdadi, Mohammad Naim Aminifard, Abbas Balouchi, Hosein Rafiemanesh, Jasem Allahyari
PURPOSE: Cataract is the leading cause of blindness and the second cause of low vision in the world. In the world, Asia has the highest number of blind population. The aim of the present systematic review and meta-analysis was to assess the frequency of clinical cataracts in Iran. MATERIALS AND METHODS: The frequency of clinical cataract was defined based on the international criteria and the measured outcome of the disease. Study selection, data extraction, and quality assessment were performed by two independent reviewers...
January 2018: Middle East African Journal of Ophthalmology
Naser Owji, Alireza Zareifard
PURPOSE: The purpose of this study was to evaluate the changes of conjunctival bacterial flora 1 year after successful dacryocystorhinostomy (DCR). METHODS: Seventy-two consecutive adult patients with successful DCR were enrolled in this study. We obtained conjunctival cultures from the operated eyes, fellow eyes, and nasal mucosa of the operated side 1 year after the operation. After the period of incubation, further evaluation was performed using standard laboratory techniques...
January 2018: Middle East African Journal of Ophthalmology
Sarat A Badmus, Ayotunde I Ajaiyeoba, Bernice O Adegbehingbe, Oluwatoyin H Onakpoya, Adenike O Adeoye, Sanyaolu A Ameye
PURPOSE: The study aimed at determining the relationship between refraction and anthropometric measurements and the relationship between the level of education and refractive status in a Nigerian young adult population. MATERIALS AND METHODS: Healthy volunteers from the students and staff of a teaching hospital in South-Western Nigeria were studied. Demographic profiles including participants' highest educational status, parental educational level, and the age at first formal school enrollment were documented...
January 2018: Middle East African Journal of Ophthalmology
Basel Turki Baarah, Raed Ali Shatnawi, Ahmed Essa Khatatbeh
PURPOSE: To report the causes of permanent severe visual impairment and blindness among Jordanian blind people. MATERIALS AND METHODS: This study was conducted on 1422 legally blind or worse vision people of all ages who attended the ophthalmic division of a medical committee for evaluation of disabled persons from July 2013 through November 2014. They were divided into two age groups: adult group (998 cases) and childhood group (<16 years, 424 cases). Patients presented reports from their ophthalmologists detailing their eye examination including best-corrected visual acuity, slit-lamp examinations, and if applicable, intraocular pressure, dilated ophthalmoscopy, and visual field and the primary cause of visual impairment...
January 2018: Middle East African Journal of Ophthalmology
Rupak Roy, Kumar Saurabh, Chinmayi Vyas, Kaustubh Deshmukh, Preeti Sharma, Dhileesh P Chandrasekharan, Aditya Bansal
AIM: This study aims to study normative choroidal thickness (CT) and Haller's and Sattler's layers thickness in normal Indian eyes. MATERIALS AND METHODS: The choroidal imaging of 73 eyes of 43 healthy Indian individuals was done using enhanced depth imaging feature of spectralis optical coherence tomography. Rraster scan protocol centered at fovea was used for imaging separately by two observers. CT was defined as the length of the perpendicular line drown from the outer border of hypereflective RPE-Bruch's complex to inner margin of choroidoscleral junction...
January 2018: Middle East African Journal of Ophthalmology
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